Compounds > lactic acid

lactic acid and efavirenz

lactic acid has been researched along with efavirenz in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (22.22)29.6817
2010's7 (77.78)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Bastow, B; Glesby, MJ; Gulick, RM; Kuritzkes, DR; Meyer, WA; Ribaudo, HJ; Shikuma, CM; Tashima, KT; Webb, N; Yang, Y1
Belgum, T; Christensen, K; Dash, A; Destache, CJ; Sharma, A; Shibata, A1
del Mar Gutiérrez, M; Díaz-Delfín, J; Domingo, JC; Domingo, P; Gallego-Escuredo, JM; Giralt, M; Gracia Mateo, M; Villarroya, F1
Belshan, M; Date, AA; Destache, CJ; Goede, M; La Bruzzo, K; Sanford, B; Shibata, A1
Belshan, M; Date, AA; Destache, CJ; Goede, M; McMullen, E; Pham, A; Sanford, B; Shibata, A; Zhou, Y1
Ball, C; Chaowanachan, T; Krogstad, E; Woodrow, KA1
Arend, C; Dringen, R; Rother, A; Stolte, S1
Araújo, F; Barreiros, L; Cunha-Reis, C; das Neves, J; Ferreira, D; Machado, A; Nunes, R; Sarmento, B; Seabra, V; Segundo, MA1

Trials

1 trial(s) available for lactic acid and efavirenz

ArticleYear
Metabolic effects of protease inhibitor-sparing antiretroviral regimens given as initial treatment of HIV-1 Infection (AIDS Clinical Trials Group Study A5095).
    Journal of acquired immune deficiency syndromes (1999), 2007, Apr-15, Volume: 44, Issue:5

    Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; Blood Glucose; Body Composition; Cyclopropanes; Dideoxynucleosides; Double-Blind Method; Female; HIV Infections; HIV-1; Humans; Insulin Resistance; Lactic Acid; Lamivudine; Lipids; Male; Reverse Transcriptase Inhibitors; Zidovudine

2007

Other Studies

8 other study(ies) available for lactic acid and efavirenz

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Combination antiretroviral drugs in PLGA nanoparticle for HIV-1.
    BMC infectious diseases, 2009, Dec-09, Volume: 9

    Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Cyclopropanes; Drug Carriers; Drug Combinations; Drug Compounding; HIV Infections; Humans; Lactic Acid; Lopinavir; Macrophages; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Pyrimidinones; Ritonavir

2009
Effects of nevirapine and efavirenz on human adipocyte differentiation, gene expression, and release of adipokines and cytokines.
    Antiviral research, 2011, Volume: 91, Issue:2

    Topics: Adipocytes; Adipogenesis; Adipokines; Alkynes; Anti-Retroviral Agents; Benzoxazines; CCAAT-Enhancer-Binding Protein-alpha; Cell Survival; Cells, Cultured; Cyclopropanes; Cytokines; Down-Regulation; Gene Expression; Hepatocyte Growth Factor; Humans; Lactic Acid; Microbial Sensitivity Tests; Nevirapine; Plasminogen Activator Inhibitor 1; PPAR gamma; RNA-Directed DNA Polymerase; Sterol Regulatory Element Binding Protein 1

2011
Development and evaluation of a thermosensitive vaginal gel containing raltegravir+efavirenz loaded nanoparticles for HIV prophylaxis.
    Antiviral research, 2012, Volume: 96, Issue:3

    Topics: Alkynes; Anti-HIV Agents; Benzoxazines; Chromatography, High Pressure Liquid; Cyclopropanes; Drug Carriers; Drug Evaluation, Preclinical; Gels; HeLa Cells; HIV Infections; HIV-1; Humans; Lactic Acid; Microbial Sensitivity Tests; Nanoparticles; Phagocytosis; Poloxamer; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Pyrrolidinones; Raltegravir Potassium; Temperature; Time Factors

2012
Polymeric nanoparticles containing combination antiretroviral drugs for HIV type 1 treatment.
    AIDS research and human retroviruses, 2013, Volume: 29, Issue:5

    Topics: Alkynes; Anti-HIV Agents; Benzoxazines; CD4-Positive T-Lymphocytes; Cell Line; Cell Survival; Cyclopropanes; Drug Therapy, Combination; HeLa Cells; HIV Infections; HIV-1; Humans; Lactic Acid; Lopinavir; Microscopy, Confocal; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Subcellular Fractions; U937 Cells

2013
Drug synergy of tenofovir and nanoparticle-based antiretrovirals for HIV prophylaxis.
    PloS one, 2013, Volume: 8, Issue:4

    Topics: Adenine; Alkynes; Animals; Anti-HIV Agents; Benzoxazines; Cell Line; Cervix Uteri; Chemistry, Pharmaceutical; Cyclopropanes; Delayed-Action Preparations; Drug Carriers; Drug Synergism; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Inhibitory Concentration 50; Lactic Acid; Macaca; Models, Biological; Nanoparticles; Organophosphonates; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Saquinavir; Spectroscopy, Fourier Transform Infrared; Tenofovir; Tissue Culture Techniques

2013
Consequences of a Chronic Exposure of Cultured Brain Astrocytes to the Anti-Retroviral Drug Efavirenz and its Primary Metabolite 8-Hydroxy Efavirenz.
    Neurochemical research, 2016, Volume: 41, Issue:12

    Topics: Alkynes; Animals; Animals, Newborn; Anti-HIV Agents; Astrocytes; Benzoxazines; Brain; Cell Survival; Cells, Cultured; Cyclopropanes; Glucose; Lactic Acid; Rats, Wistar; Reverse Transcriptase Inhibitors; Stereoisomerism

2016
Nanoparticles-in-film for the combined vaginal delivery of anti-HIV microbicide drugs.
    Journal of controlled release : official journal of the Controlled Release Society, 2016, 12-10, Volume: 243

    Topics: Administration, Intravaginal; Alkynes; Animals; Anti-HIV Agents; Benzoxazines; Chemistry, Pharmaceutical; Cyclopropanes; Drug Carriers; Drug Combinations; Drug Delivery Systems; Female; Lactic Acid; Mice; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Tenofovir; Tissue Distribution

2016