lactic acid has been researched along with deoxyglucose in 196 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 36 (18.37) | 18.7374 |
| 1990's | 51 (26.02) | 18.2507 |
| 2000's | 61 (31.12) | 29.6817 |
| 2010's | 39 (19.90) | 24.3611 |
| 2020's | 9 (4.59) | 2.80 |
| Authors | Studies |
|---|---|
| Mrus, JM; Nguyêñ, VT; Russell, RR; Taegtmeyer, H | 1 |
| denHollander, JA; Friedmann, G; Heindel, W; Heiss, WD; Herholz, K; Kugel, H; Luyten, PR; Pietrzyk, U; Voges, J | 1 |
| Barrett, E; Frederick, B; Gore, JC; Laughlin, M; Majumdar, S; Zahler, R | 1 |
| Greenberg, JH; Hamar, J; Harris, V; Reivich, M; Welsh, FA | 1 |
| Chayoth, R; Field, CJ; Marliss, EB; Montambault, M | 1 |
| Chugani, HT; Hovda, DA; Phelps, ME; Villablanca, JR; Xu, WF | 1 |
| Nguyêñ, VT; Schneider, CA; Taegtmeyer, H | 1 |
| Hospod, FE; Newman, GC; Schissel, SL | 1 |
| Foot, E; Leighton, B | 1 |
| Barron, JT; Kopp, SJ; Messer, JV; Tow, JP | 1 |
| Kainulainen, H; Ruskoaho, H; Takala, TE; Virtanen, P | 1 |
| Hatfaludy, S; Shansky, J; Vandenburgh, HH | 1 |
| Fujiwara, T; Horikoshi, H; Ushiyama, I; Yoshioka, S; Yoshioka, T | 1 |
| Brodie, D; Bünger, R; Stiegler, H; Swindall, B; Walter, G; Zdunek, D | 1 |
| Kuschinsky, W; Schröck, H | 1 |
| Bashan, N; Hagai, Y; Moses, SW; Potashnik, R | 1 |
| Caputo, A; Carapella, CM; Del Carlo, C; Fanciulli, M; Floridi, A; Giorno, S; Paggi, MG; Silvestrini, B; Zupi, G | 1 |
| Hospod, FE; Newman, GC; Wu, P | 1 |
| Korf, J; Kuhr, WG | 1 |
| Cozzi, PJ; Davis, HR; Glagov, S; Lyon, RT; Sylora, J; Zarins, CK | 1 |
| Hakomori, S; Okada, Y; Radin, NS | 1 |
| Challiss, RA; Leighton, B; Lozeman, FJ; Newsholme, EA | 1 |
| Lanks, KW | 1 |
| Barrio, JR; Hoffman, EJ; Huang, SC; Krivokapich, J; Nissenson, C; Phelps, ME; Williams, BA | 1 |
| Hazel, JR; Sidell, BD | 1 |
| Allen, DG; Pirolo, JS | 1 |
| Coetzee, WA; Opie, LH | 1 |
| Miller, LP; Oldendorf, WH; Villeneuve, JB | 1 |
| Diribe, CO; Warhurst, DC | 1 |
| Greenberg, JH; Harris, VA; O'Flynn, R; Reivich, M; Tanaka, K; Welsh, FA | 1 |
| Chen, KS; Lardy, HA | 1 |
| Giger, U; Meyer, UA | 1 |
| Bowen-Pope, DF; Rubin, H | 1 |
| Belur, E; Dluz, SM; Goodman, MN; McElaney, MA; Ruderman, NB | 1 |
| Hansen, IL; Kerr, DS; Levy, MM | 1 |
| Dills, SS; Seno, S | 1 |
| Opie, LH; Saman, S | 1 |
| Ford, SA; Jones, AR | 1 |
| Johansen, T | 1 |
| Yamanishi, K | 1 |
| Hassinen, IE; Ruskoaho, HJ; Takala, TE | 1 |
| Fried, SK; Lavau, M; Pi-Sunyer, FX | 1 |
| Allsopp, D; Bailey, PJ; Higgins, TJ | 2 |
| Allsopp, D; Bailey, PJ; D'Souza, ED; Higgins, TJ | 1 |
| Kopsidas, G; MacPhee, DG | 1 |
| Fürnsinn, C; Leighton, B; Radda, GK; Sanderson, AL | 1 |
| Go, KG; Heesters, MA; Kamman, RL; Mooyaart, EL; Paans, AM; Pruim, J; Vaalburg, W | 1 |
| Kunievsky, B; Pretsky, J; Yavin, E | 1 |
| Arcuri, E; Barbieri, R; Fanciulli, M; Floridi, A; Pulselli, R | 1 |
| Adachi, K; Cruz, NF; Dienel, GA; Sokoloff, L | 1 |
| Krukenkamp, IB; Levitsky, S; Malikin, L; McCully, JD; Myrmel, T | 1 |
| Donovan, CM; Sumida, KD | 1 |
| Bergman, J; Heinonen, OJ; Knuuti, MJ; Nuutila, P; Ruotsalainen, U; Solin, O; Teräs, M; Voipio-Pulkki, LM; Wegelius, U; Yki-Järvinen, H | 1 |
| Budohoski, L; Challiss, RA; Dubaniewicz, A; Langfort, J; Newsholme, EA | 1 |
| Franchi, A; Newell, K; Pouysségur, J; Tannock, I | 1 |
| Hunter, ES; Tugman, JA | 1 |
| Benington, JH; Swanson, RA | 1 |
| Avogaro, A; Crepaldi, C; del Prato, S; Miola, M; Pavan, P; Tiengo, A; Valerio, A | 1 |
| Böttcher, U; Eblenkamp, M; Fischer, Y; Jüngling, E; Kammermeier, H; Rösen, P; Thomas, J | 1 |
| Bevan, S; Dimitriadis, G; Krause, U; Leighton, B; Newsholme, EA; Parry-Billings, M; Piva, T; Sasson, S; Wegener, G; Young, M | 1 |
| Desplanches, D; Dubaniewicz, A; Langfort, J; Mayet-Sornay, MH; Zernicka, E | 1 |
| Bashan, N; Demshchak, E; Khamaisi, M; Potashnik, R; Rudich, A; Tirosh, A; Tritschler, H; Wessel, K | 1 |
| Abumrad, NN; Molina, PE; Williams, P | 1 |
| Fujibayashi, Y; Ishii, Y; Sadato, N; Tsuchida, T; Waki, A; Yokoyama, A; Yonekura, Y | 1 |
| Bruni, P; Farnararo, M; Meacci, E; Romiti, E; Vasta, V | 1 |
| Alger, JR; Bonavita, S; Di Chiro, G; Duyn, JH; Lundbom, N; Raman, R; Tedeschi, G | 1 |
| Dréau, D; Foster, M; Morton, DS; Sonnenfeld, G; Swiggett, JP | 1 |
| Lazarus, DD; Moldawer, LL; Trimble, LA | 1 |
| Guérin, M; Manon, S | 1 |
| Kadiata, MM; Kirk, O; Ladrière, L; Malaisse, WJ | 1 |
| Charron, MJ; Galuska, D; Ryder, JW; Stenbit, AE; Tsao, TS; Zierath, JR | 1 |
| Dréau, D; Foster, M; Fowler, N; Morton, DS; Sonnenfeld, G | 1 |
| Hertz, L; Juurlink, BH; Marrif, H; Newman, GC; Peng, L; Swanson, RA | 1 |
| Miller, JJ; Payne, RS; Rigor, BM; Schurr, A | 1 |
| Goucham, AY; Nicolaïdis, S | 1 |
| Beisswenger, PJ; Howell, SK; Lal, S; Szwergold, BS; Touchette, AD | 1 |
| Halestrap, AP; Kerr, PM; Suleiman, MS | 1 |
| Ceddia, RB; Curi, R; William, WN | 1 |
| Bassetto, F; Fabris, R; Federspil, G; Girard, J; Leturque, A; Lombardi, AM; Serra, R; Vettor, R | 1 |
| Adrian, TE; Li, J | 1 |
| Galbo, H; Hellsten, Y; Ihlemann, J; Ploug, T | 2 |
| Briski, KP | 1 |
| Bou-Hanna, C; Jarry, A; Laboisse, CL; Le Goffe, C; Vallette, G | 1 |
| Ishihara, H; Urban, JP | 1 |
| Enevoldsen, LH; Fluckey, JD; Galbo, H; Stallknecht, B | 1 |
| Armstrong, VL; Clulow, J; Jones, RC; Murdoch, RN | 1 |
| Hardin, CD; Lloyd, PG; Sturek, M | 1 |
| Borderie, D; Ekindjian, OG; Hernvann, A; Le Marechal, H | 1 |
| Adachi, T; Arakawa, K; Ikezawa, K; Kano-Ishihara, T; Matsumoto, T; Oku, A; Saito, A; Tsuda, K; Ueta, K; Yasuda, K | 1 |
| Benham, CD; Cater, HL; Sundstrom, LE | 1 |
| Brito, MN; Brito, NA; Kettelhut, IC; Migliorini, RH; Timo-Iaria, C | 1 |
| Fujibayashi, Y; Sadato, N; Waki, A; Yano, R; Yonekura, Y; Yoshimoto, M | 1 |
| Jahan, I; Ng, R; Thornalley, PJ | 1 |
| Anai, M; Arakawa, K; Asano, T; Fujita, T; Funaki, M; Kano-Ishihara, T; Kikuchi, M; Nawano, M; Oka, Y; Oku, A; Saito, A; Ueta, K; Umebayashi, I | 1 |
| Hu, YP; Lampidis, TJ; Liu, H; Priebe, W; Savaraj, N | 1 |
| Gloe, T; Hoffmann, A; Pohl, U | 1 |
| Galbo, H; Ihlemann, J; Ploug, T | 1 |
| Adhikari, JS; Bauch, T; Chandana, S; Dwarkanath, BS; Jain, V; Muller, WU; Streffer, C; Zolzer, F | 1 |
| Geschwind, JF; Ko, YH; Pedersen, PL | 1 |
| Kakinuma, Y; Katoh, S; Mitsui, Y; Miyauchi, T; Suzuki, T; Yuki, K | 1 |
| Bongard, RD; Dawson, CA; Kettenhofen, NJ; Merker, MP; Okamoto, Y | 1 |
| Smoak, IW | 1 |
| Choi, JJ; Choi, JW; Kim, HC; Kim, HS; Kim, WK; Ko, KH; Lee, JC; Lee, SJ; Ryu, JR; Shin, CY | 1 |
| Campbell, SE; Febbraio, MA | 1 |
| Chan, BS; Endo, S; Kanai, N; Schuster, VL | 1 |
| Alvarez, J; Azhar, J; Buczek, M; Lust, WD; Ratcheson, RA; Selman, WR; Zhou, Y | 1 |
| Lampidis, TJ; Liu, H; Priebe, W; Savaraj, N | 1 |
| Magistretti, PJ; Pellerin, L | 1 |
| Burckhart, MF; Coles, JA; Drouhault, D; Martiel, JL; Véga, C | 1 |
| Bonvento, G; Chatton, JY; Magistretti, PJ; Pellerin, L; Steiner, P; Tanaka, K; Voutsinos-Porche, B; Welker, E | 1 |
| Cohen, DM; Quast, MJ; Wei, J | 1 |
| Chatton, JY; Magistretti, PJ; Pellerin, L | 1 |
| Han, YY; Reynolds, IJ; Vergun, O | 1 |
| Bikopoulos, GJ; Ceddia, RB; Hilliker, AJ; Sweeney, G | 1 |
| Casson, RJ; Chidlow, G; Osborne, NN; Wood, JP | 1 |
| Clow, KA; Driedzic, WR; MacCormack, TJ; Rodnick, KJ | 1 |
| Amico, MC; Mattioli, F; Memoli, A; Muller, A; Romanelli, L; Savini, G | 1 |
| Bünger, R; Chung, SJ; Kang, YH; Lee, SH; Lee, YJ; Park, HS | 1 |
| Alakhov, VY; Batrakova, EV; Kabanov, AV; Li, S; Li, Y; Miller, DW; Persidsky, Y; Vinogradov, SV; Zhang, Y | 1 |
| Lampidis, TJ; Liu, H; Maher, JC; Priebe, W; Savaraj, N | 1 |
| De, S; Miller, DW; Robinson, DH | 1 |
| Aasum, E; Edgley, A; Furler, SM; Larsen, T; Ljung, B; Oakes, ND; Severson, D; Thalén, P | 1 |
| Fokt, I; Ginalski, K; Krishan, A; Kurtoglu, M; Lampidis, TJ; Lesyng, B; Liu, H; Maher, JC; Priebe, W; Rudnicki, WR; Sheft, V; Szymanski, S | 1 |
| Gozal, D; Gozal, E; R Sachleben, L; Véga, C | 1 |
| Battu, CE; da Silveira, CK; de Souza, CG; de Souza, DO; Gonçalves, CA; Gravina, FS; Kawano, C; Leszczinski, DN; Londero, LG; Muller, AP; Perry, ML; Rotta, LN; Schweigert, ID | 1 |
| Coe, I; Eguchi, M; Palanivel, R; Shuralyova, I; Sweeney, G | 1 |
| Arya, MB; Chandna, S; Dwarakanath, BS; Khaitan, D | 1 |
| Driedzic, WR; MacCormack, TJ | 1 |
| Beesley, AH; Boag, JM; Cummings, AJ; de Klerk, NH; Firth, MJ; Ford, J; Freitas, JR; Hoffmann, K; Kees, UR | 1 |
| Kurtoglu, M; Lampidis, TJ; Maher, JC; Savaraj, N; Wangpaichitr, M | 1 |
| Mobasheri, A; Platt, N; Shakibaei, M; Thorpe, C | 1 |
| Hendrikse, AS; Hunter, AJ; Renan, MJ | 1 |
| Baar, K; Babraj, JA; Cuthbertson, DJ; Green, KA; Hardie, DG; Leese, GP; Mustard, KJ; Rennie, MJ; Sutherland, C; Thomason-Hughes, M; Towler, MC; Wackerhage, H | 1 |
| Arik, E; Türkel, S | 1 |
| Charles, PE; Comte, R; Dufour, J; Dunn-Siegrist, I; Pugin, J; Tissières, P | 1 |
| Gao, Z; Liu, D; Liu, Z; Ye, J; Yin, J | 1 |
| Damon, TL; Erlichman, JS; Hart, M; Hewitt, A; Kurascz, J; Leiter, JC; Li, A | 1 |
| Angulo, C; Brauchi, S; Castro, MA; Concha, II; Nualart, F | 1 |
| Burdakov, D; Fugger, L; González, JA; Jensen, LT | 1 |
| Polakof, S; Soengas, JL | 1 |
| Bongard, RD; Krenz, GS; Lindemer, BJ; Merker, MP | 1 |
| Bak, LK; Ring, A; Schousboe, A; Sonnewald, U; Waagepetersen, HS; Walls, AB | 1 |
| Håberg, AK; Qu, H; Sonnewald, U | 1 |
| Devaskar, SU; Ehninger, D; Fung, C; Sankar, R; Shin, BC; Shin, D; Silva, A; Thamotharan, S; Zhao, Y | 1 |
| Avall-Lundqvist, E; Hernlund, E; Hjerpe, E; Shoshan, M | 1 |
| Cigorraga, SB; Galardo, MN; Meroni, SB; Pellizzari, EH; Riera, MF | 1 |
| Ding, Y; Fodstad, O; Khong, HT; Liu, H; Tan, M; Yu, D; Zhao, YH; Zhou, M | 1 |
| Baverel, G; Dubourg, L; Knouzy, B; Michoudet, C | 1 |
| Andreesen, R; Gottfried, E; Hartmannsgruber, G; Kreutz, M; Kunz-Schughart, LA; Peter, K; Peuker, A; Reichle, A; Rogenhofer, S; Waibel, H; Wehrstein, M | 1 |
| Goto, M; Gotou, M; Hanamura, I; Hiramatsu, A; Imai, N; Imamura, A; Mihara, H; Miwa, H; Mizuno, S; Nitta, M; Shikami, M; Suganuma, K; Takahashi, M; Wakabayashi, M; Watarai, M; Yamamoto, H | 1 |
| Ambrósio, AF; Carvalho, RA; Cristóvão, AJ; Duarte, JM; Garrido, MJ; Santiago, AR | 1 |
| Davis-Malesevich, M; Fokt, I; Frederick, MJ; Myers, JN; Ow, TJ; Pickering, CR; Priebe, W; Sandulache, VC; Zhou, G | 1 |
| Mannowetz, N; Wandernoth, PM; Wennemuth, G | 1 |
| Barros, LF; Deitmer, JW; Gutiérrez, R; Jakoby, P; Ruminot, I; Schmidt, E | 1 |
| Arunan, V; Beloueche-Babari, M; Eykyn, TR; Falck Miniotis, M; Leach, MO; Marais, R; Workman, P | 1 |
| Futscher, BW; Klimecki, WT; Pacheco, S; Severson, P; Zhao, F | 1 |
| Chen, JJ; Fang, ZG; Lin, DJ; Liu, LL; Liu, Q; Long, ZJ; Wang, LX; Wang, SW; Xu, DF; Yan, M; Zheng, FM | 1 |
| Hoffmann, C; Jaeckel, M; Lewerenz, J; Methner, A; Noack, R; Pfeiffer, A; Pouya, A; Schacht, T; Schäfer, MK; Schweiger, S; Winter, J | 1 |
| Brenneman, R; Kurtoglu, M; Lampidis, TJ; Liu, H; Sullivan, EJ | 1 |
| Teitell, MA; TeSlaa, T | 1 |
| Birnbaumer, L; Lutas, A; Yellen, G | 1 |
| Chaudhuri, AD; Choi, DC; Junn, E; Kabaria, S; Mouradian, MM | 1 |
| Chen, J; Dai, Y; Jia, L; Jiang, Z; Li, Y; Lin, L; Lu, Y; Ou, M; Shao, J; Wang, J; Xiang, L; Yang, X | 1 |
| Baker, AF; Carbajal, L; Gill, A; Hanke, NT; Malm, SW | 1 |
| Cheng, SP; Chuang, JH; Lin, LL; Shieh, DB; Wang, PW; Wang, SY; Wei, YH | 1 |
| Bradley, EA; Genders, AJ; Keske, MA; Rattigan, S; Richards, SM; Zhang, L | 1 |
| Beleza, RO; Cunha, RA; Köfalvi, A; Lemos, C; Marques, JM; Pinheiro, BS; Rial, D; Rodrigues, RJ | 1 |
| Cao, N; Deng, J; Du, G; Duan, Y; Geng, S; Guo, Z; Lin, H; Ma, X; Meng, M; Zheng, Y | 1 |
| Hitoe, S; Matsuda, H; Nakamura, S; Shimoda, H; Takeda, S; Toda, K | 1 |
| Choi, SC; Croker, BP; Kanda, N; Morel, L; Xu, Z; Yin, Y; Zeumer, L | 1 |
| Fei, Q; Li, J; Sun, Y; Wang, F; Zhang, C; Zhang, D; Zhu, C | 1 |
| Baud, MO; Magistretti, PJ; Nguyen, A; Parafita, J; Petit, JM | 1 |
| Davies, KP; Deng, GG; Wang, Y | 1 |
| Clow, KA; Driedzic, WR; Gendron, RL; Hall, JR; Paradis, H; Ralhan, A; Short, CE | 1 |
| Dang, CV; Hajjar, S; Ishida, Y; Le, AD; Shi, H; Tang, X; Xu, Q; Zhang, Q | 1 |
| Fan, M; Ha, T; Kalbfleisch, J; Kao, R; Li, C; Liu, L; Ma, H; Tu, F; Wang, R; Wang, X; Williams, D; Xu, J; Yu, K; Zhang, X; Zheng, Z | 1 |
| Kitamura, J; Morishima, H; Shinohara, Y; Takahashi, N; Takahashi, T; Washio, J | 1 |
| Alsady, M; Baumgarten, R; Bekkenkamp-Grovenstein, M; Carmone, C; de Groot, T; Deen, PMT; Engelke, U; Korstanje, R; Kortenoeven, MLA; Neijman, K; Wevers, R | 1 |
| Burger, MC; Eriksson, JA; Hartel, I; Harter, PN; Mittelbronn, M; Rieger, J; Steinbach, JP; Urban, H; von Renesse, J; Wanka, C | 1 |
| Bi, H; Li, Q; Ma, J; Nie, F; Pan, B; Qin, Z; Xie, X; Zhao, R | 1 |
| Elhammali, AE; Floberg, JM; Huang, X; McCormick, ML; Patti, GJ; Rashmi, R; Schwarz, JK; Spitz, DR | 1 |
| Dzeja, PD; Folmes, CD; Herrmann, J; Jeon, R; Jiang, X; Lerman, A; Vuckovic, I; Wang, F; Zhang, S | 1 |
| Brennan, D; Deuchar, GA; Holmes, WM; Macrae, IM; Santosh, C; Shaw, M | 1 |
| Chan, O; Farhat, R; Fisher, SJ; Knight, N; Sejling, AS; Su, G | 1 |
| Bhatt, AN; Chawla, AS; Dwarakanath, BS; Pandey, S; Roy, BG; Saluja, D; Singh, S | 1 |
| Jia, J; Jiang, X; Li, L; Ma, J; Peng, G; Tang, H; Wu, Z; Xu, M; Xu, X; Yao, J; Yao, K | 1 |
| Wu, X; Yan, Z; Zhang, J; Zhao, M | 1 |
| Christofi, M; Forrester, JV; Klaska, IP; Kuffova, L; Le Sommer, S; Mölzer, C | 1 |
| Adam, S; Böhm, C; Böttcher, M; Faas, M; Hofmann, J; Krishnacoumar, B; Krönke, G; Mougiakakos, D; Müller, DIH; Schett, G; Scholtysek, C; Sonnewald, U; Stoll, C; Taubmann, J | 1 |
| Chen, H; Gu, J; Li, T; Liu, K; Liu, M; Tan, C; Xiao, X; Zhang, H | 1 |
| Fink, K; Kreft, M; Vardjan, N; Velebit, J; Zorec, R | 1 |
| Hostiuc, M; Hostiuc, S; Negoi, I | 1 |
| Chen, X; Han, L; Hu, Z; Li, C; Li, X; Liu, J; Wu, T; Zhao, W; Zhou, J | 1 |
| Cheng, X; Geng, YN; Hu, Y; Ruan, QQ; Shi, ZB; Zhao, M; Zhu, LL | 1 |
2 review(s) available for lactic acid and deoxyglucose
| Article | Year |
|---|---|
Techniques to monitor glycolysis.
Topics: 4-Chloro-7-nitrobenzofurazan; Biochemistry; Carbon Radioisotopes; Deoxyglucose; Enzymes; Fluorodeoxyglucose F18; Glucose; Glycolysis; Hexokinase; Humans; Lactic Acid; Phosphofructokinases; Pyruvate Kinase; Water | 2014 |
Markers of hyperglycemia in the vitreous humor. A systematic review and meta-analysis.
Topics: 3-Hydroxybutyric Acid; Biomarkers; Deoxyglucose; Forensic Medicine; Fructosamine; Glucose; Humans; Hyperglycemia; Lactic Acid; Postmortem Changes; Vitreous Body | 2021 |
2 trial(s) available for lactic acid and deoxyglucose
| Article | Year |
|---|---|
Metformin reduces systemic methylglyoxal levels in type 2 diabetes.
Topics: Adult; Aged; Deoxyglucose; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Female; Humans; Hypoglycemic Agents; Insulin; Lactic Acid; Male; Metformin; Middle Aged; Osmolar Concentration; Pyruvaldehyde; Sulfonylurea Compounds; Treatment Outcome | 1999 |
5-aminoimidazole-4-carboxamide 1-beta-D-ribofuranoside acutely stimulates skeletal muscle 2-deoxyglucose uptake in healthy men.
Topics: Adult; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Biopsy; Blood Glucose; Deoxyglucose; Glycogen; Health; Hormones; Humans; Insulin; Isoenzymes; Lactic Acid; Male; Multienzyme Complexes; Muscle, Skeletal; Protein Serine-Threonine Kinases; Ribonucleosides; Time Factors | 2007 |
192 other study(ies) available for lactic acid and deoxyglucose
| Article | Year |
|---|---|
Fasting and lactate unmask insulin responsiveness in the isolated working rat heart.
Topics: Animals; Deoxyglucose; Fasting; Fluorodeoxyglucose F18; Glucose; Glycogen; Heart; In Vitro Techniques; Insulin; Lactates; Lactic Acid; Male; Myocardial Contraction; Myocardium; Perfusion; Rats; Rats, Sprague-Dawley; Time Factors | 1992 |
In vivo imaging of glucose consumption and lactate concentration in human gliomas.
Topics: Adult; Brain Neoplasms; Deoxyglucose; Female; Fluorodeoxyglucose F18; Glioma; Glucose; Glycolysis; Humans; Lactates; Lactic Acid; Magnetic Resonance Imaging; Male; Middle Aged; Prognosis; Tomography, Emission-Computed | 1992 |
NMR determination of myocardial pH in vivo: separation of tissue inorganic phosphate from blood 2,3-DPG.
Topics: 2,3-Diphosphoglycerate; Animals; Bicarbonates; Deoxyglucose; Diphosphoglyceric Acids; Glycerophosphates; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Models, Cardiovascular; Models, Structural; Myocardium; Phosphates; Phosphocreatine; Phosphorus; Rats; Rats, Inbred Strains; Sodium; Sodium Bicarbonate | 1991 |
Effect of ischemia and reperfusion on lambda of the lumped constant of the [14C]deoxyglucose technique.
Topics: Adenosine Triphosphate; Algorithms; Animals; Brain Ischemia; Carbon Radioisotopes; Cats; Cerebrovascular Circulation; Deoxyglucose; Glucose; Lactates; Lactic Acid; Male; Phosphocreatine | 1992 |
Enhanced 2-deoxy-D-glucose uptake and metabolism in splenocytes from diabetic and diabetes-prone BB rats. Further evidence to support prior in vivo activation.
Topics: Animals; Carbon Dioxide; Deoxyglucose; Diabetes Mellitus, Experimental; Female; Glucose; Lactates; Lactic Acid; Male; Mitogens; Pyruvates; Rats; Spleen | 1991 |
Metabolic maturation of the brain: a study of local cerebral glucose utilization in the developing cat.
Topics: 3-Hydroxybutyric Acid; Aging; Animals; Animals, Newborn; Autoradiography; Blood Glucose; Brain; Cats; Deoxyglucose; Glucose; Hydroxybutyrates; Kinetics; Lactates; Lactic Acid; Telencephalon | 1991 |
Feeding and fasting determine postischemic glucose utilization in isolated working rat hearts.
Topics: Animals; Coronary Disease; Deoxyglucose; Eating; Fasting; Fluorodeoxyglucose F18; Glucose; Heart; In Vitro Techniques; Lactates; Lactic Acid; Male; Myocardium; Rats; Rats, Inbred Strains; Reperfusion; Triglycerides | 1991 |
Ischemic brain slice glucose utilization: effects of slice thickness, acidosis, and K+.
Topics: Animals; Brain; Buffers; Deoxyglucose; Glucose; Glycolysis; Hydrogen-Ion Concentration; Ischemic Attack, Transient; Kinetics; Lactates; Lactic Acid; Male; Phosphorylation; Potassium; Rats; Rats, Inbred Strains | 1991 |
The effects of amylin on carbohydrate metabolism in skeletal muscle in vitro and in vivo.
Topics: Amyloid; Animals; Biological Transport; Carbohydrate Metabolism; Deoxyglucose; Glucose; Glycogen; Insulin; Islet Amyloid Polypeptide; Kinetics; Lactates; Lactic Acid; Male; Muscles; Oxidation-Reduction; Phosphorylation; Rats; Rats, Inbred Strains | 1990 |
Effects of altering carbohydrate metabolism on energy status and contractile function of vascular smooth muscle.
Topics: Adenosine Triphosphate; Animals; Carbohydrate Metabolism; Carotid Arteries; Chemical Phenomena; Chemistry, Physical; Deoxyglucose; Energy Metabolism; Glucose; Glycogen; Hydrogen-Ion Concentration; Iodoacetates; Iodoacetic Acid; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Muscle Contraction; Muscle, Smooth, Vascular; Phosphates; Phosphocreatine; Potassium Chloride; Swine | 1989 |
Training increases cardiac glucose uptake during rest and exercise in rats.
Topics: Animals; Blood Glucose; Blood Pressure; Deoxyglucose; Fatty Acids, Nonesterified; Glucose; Heart Rate; Lactates; Lactic Acid; Male; Myocardium; Physical Conditioning, Animal; Physical Exertion; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Rest; Tissue Distribution | 1989 |
Metabolic alterations induced in cultured skeletal muscle by stretch-relaxation activity.
Topics: Animals; Cells, Cultured; Chick Embryo; Cycloheximide; Deoxy Sugars; Deoxyglucose; Electrophysiology; Kinetics; Lactates; Lactic Acid; Muscle Contraction; Muscle Proteins; Muscles; Physical Stimulation | 1989 |
Characterization of new oral antidiabetic agent CS-045. Studies in KK and ob/ob mice and Zucker fatty rats.
Topics: Adipose Tissue; Animals; Benzopyrans; Blood Glucose; Chromans; Deoxyglucose; Diabetes Mellitus, Experimental; Fatty Acids, Nonesterified; Hypoglycemic Agents; Insulin; Insulin Resistance; Ketone Bodies; Lactates; Lactic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Obesity; Rats; Rats, Inbred Strains; Rats, Zucker; Receptor, Insulin; Thiazoles; Thiazolidinediones; Triglycerides; Troglitazone | 1988 |
Pyruvate attenuation of hypoxia damage in isolated working guinea-pig heart.
Topics: Animals; Carbon Dioxide; Cardiomyopathies; Deoxyglucose; Fatty Acids; Glucose; Guinea Pigs; Heart; Hemodynamics; Hydrogen-Ion Concentration; Hypoxia; In Vitro Techniques; Lactates; Lactic Acid; Male; Oxygen; Perfusion; Phosphates; Purine Nucleosides; Pyruvates; Ribose; Veins | 1986 |
Cerebral blood flow, glucose use, and CSF ionic regulation in potassium-depleted rats.
Topics: Acid-Base Equilibrium; Animals; Brain; Carbon Dioxide; Cerebrovascular Circulation; Deoxyglucose; Glucose; Hydrogen-Ion Concentration; Ions; Lactates; Lactic Acid; Male; Potassium Deficiency; Rats; Rats, Inbred Strains | 1988 |
Impaired carbohydrate metabolism of polymorphonuclear leukocytes in glycogen storage disease Ib.
Topics: Adenosine Triphosphate; Adolescent; Carbohydrate Metabolism; Child, Preschool; Deoxyglucose; Glucose; Glucosephosphate Dehydrogenase; Glycogen Storage Disease Type I; Glycolysis; Hexokinase; Humans; Lactates; Lactic Acid; Neutrophils; Osmotic Fragility; Pentose Phosphate Pathway; Phosphogluconate Dehydrogenase; Phosphorylation | 1988 |
Effect of lonidamine on human malignant gliomas: biochemical studies.
Topics: Astrocytoma; Deoxy Sugars; Deoxyglucose; Glycolysis; Hexokinase; Humans; Indazoles; Lactates; Lactic Acid; Pyrazoles; Tumor Cells, Cultured | 1988 |
Thick brain slices model the ischemic penumbra.
Topics: Animals; Body Water; Brain; Brain Ischemia; Deoxyglucose; Disease Models, Animal; Histological Techniques; In Vitro Techniques; Lactates; Lactic Acid; Microscopy, Electron | 1988 |
Extracellular lactic acid as an indicator of brain metabolism: continuous on-line measurement in conscious, freely moving rats with intrastriatal dialysis.
Topics: 2,4-Dinitrophenol; Animals; Brain; Corpus Striatum; Deoxyglucose; Dialysis; Dinitrophenols; Electron Transport; Electroshock; Extracellular Space; Glycolysis; Kainic Acid; Lactates; Lactic Acid; Male; Rats; Rats, Inbred Strains; Tetrodotoxin | 1988 |
Aortic wall metabolism in relation to susceptibility and resistance to experimental atherosclerosis.
Topics: Animals; Aorta; Aortic Coarctation; Aortic Diseases; Arteriosclerosis; Blood Pressure; Deoxyglucose; Diet, Atherogenic; Disease Susceptibility; DNA; Lactates; Lactic Acid; Oxygen Consumption; Rabbits | 1988 |
Phenotypic changes in 3T3 cells associated with the change of sphingolipid synthesis by a ceramide analog, 2-decanoylamino-3-morpholino-1-phenylpropanol (compound RV538).
Topics: Animals; Biological Transport; Cell Division; Cell Line; Ceramides; Deoxyglucose; Gangliosides; Lactates; Lactic Acid; Mice; Morpholines; Phenotype; Sphingolipids; Sphingomyelins | 1988 |
Effects of the beta-adrenoceptor agonist isoprenaline on insulin-sensitivity in soleus muscle of the rat.
Topics: 3-O-Methylglucose; Animals; Deoxyglucose; Glucose; Glucose-6-Phosphate; Glucosephosphates; Glycogen; In Vitro Techniques; Insulin; Isoproterenol; Lactates; Lactic Acid; Male; Methylglucosides; Muscles; Phosphorylation; Rats; Rats, Inbred Strains | 1986 |
Studies on the mechanism by which glutamine and heat shock increase lactate synthesis by L929 cells in the presence of insulin.
Topics: 3-O-Methylglucose; Aminooxyacetic Acid; Cell Line; Deoxyglucose; Glutamine; Glycolysis; Hot Temperature; Insulin; Kinetics; Lactates; Lactic Acid; Methylglucosides; Pyruvates; Pyruvic Acid; Transaminases | 1986 |
Measurement of glucose and 2-deoxy-2-[18F]fluoro-D-glucose transport and phosphorylation rates in myocardium using dual-tracer kinetic experiments.
Topics: Animals; Biological Transport; Deoxy Sugars; Deoxyglucose; Fluorodeoxyglucose F18; Glucose; Heart Septum; Hypoxia; Kinetics; Lactates; Lactic Acid; Myocardium; Phosphorylation; Rabbits | 1987 |
Temperature affects the diffusion of small molecules through cytosol of fish muscle.
Topics: Adenosine Triphosphate; Adenylyl Imidodiphosphate; Animals; Calcium; Cytosol; Deoxy Sugars; Deoxyglucose; Kinetics; Lactates; Lactic Acid; Muscles; Perches; Perciformes; Temperature; Viscosity | 1987 |
Assessment of techniques for preventing glycolysis in cardiac muscle.
Topics: Animals; Deoxyglucose; Ferrets; Glucose; Glycogen; Glycolysis; Heart; Iodoacetates; Iodoacetic Acid; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Myocardium; Organ Culture Techniques; Perfusion | 1986 |
Effects of components of ischemia and metabolic inhibition on delayed afterdepolarizations in guinea pig papillary muscle.
Topics: Acidosis; Action Potentials; Animals; Coronary Disease; Cyanides; Deoxyglucose; Guinea Pigs; Heart Conduction System; Hypoxia; In Vitro Techniques; Iodoacetates; Iodoacetic Acid; Lactates; Lactic Acid; Membrane Potentials; Myocardial Contraction; Papillary Muscles; Potassium | 1987 |
Pretreatment with 3-O-methyl-D-glucose or 2-deoxy-D-glucose attenuates the post-mortem rise in rat brain lactate.
Topics: 3-O-Methylglucose; Animals; Brain Chemistry; Deoxy Sugars; Deoxyglucose; Injections, Intravenous; Lactates; Lactic Acid; Methylglucosides; Methylglycosides; Postmortem Changes; Premedication; Rats; Rats, Inbred Strains | 1986 |
A study of the uptake of chloroquine in malaria-infected erythrocytes. High and low affinity uptake and the influence of glucose and its analogues.
Topics: 3-O-Methylglucose; Animals; Binding Sites; Chloroquine; Deoxyglucose; Erythrocytes; Glucose; Lactates; Lactic Acid; Malaria; Methylglucosides; Mice; Plasmodium berghei; Stereoisomerism; Time Factors | 1985 |
Regional alterations in glucose consumption and metabolite levels during postischemic recovery in cat brain.
Topics: Adenosine Triphosphate; Animals; Blood Glucose; Brain; Brain Ischemia; Carbon Dioxide; Cats; Deoxyglucose; Female; Glucose; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Male; Oxygen; Phosphates | 1985 |
Multiple requirements for glycogen synthesis by hepatocytes isolated from fasted rats.
Topics: Amino Acids, Branched-Chain; Animals; Cycloheximide; Deoxyglucose; Dihydroxyacetone; Fasting; Glucose; In Vitro Techniques; Kinetics; Lactates; Lactic Acid; Liver; Liver Glycogen; Male; Puromycin; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1985 |
Induction of delta-aminolevulinate synthase and cytochrome P-450 hemoproteins in hepatocyte culture. Effect of glucose and hormones.
Topics: 3-O-Methylglucose; 5-Aminolevulinate Synthetase; Animals; Bucladesine; Cells, Cultured; Chick Embryo; Cytochrome P-450 Enzyme System; Deoxyglucose; Enzyme Induction; Fructose; Glucagon; Glucose; Glycerol; Insulin; Kinetics; Lactates; Lactic Acid; Liver; Methylglucosides | 1981 |
Growth stimulatory precipitates of Ca2+ and pyrophosphate.
Topics: Animals; Biological Transport; Calcium Pyrophosphate; Cell Division; Cell Membrane; Cell Membrane Permeability; Chemical Precipitation; Choline; Deoxyglucose; Diphosphates; Extracellular Space; Kinetics; Lactates; Lactic Acid; Mice; Mitogens; Proteins; Solubility; Uridine | 1983 |
Glucose uptake and insulin sensitivity in rat muscle: changes during 3-96 weeks of age.
Topics: Aging; Animals; Biological Transport; Deoxyglucose; Dose-Response Relationship, Drug; Glucose; Glycolysis; In Vitro Techniques; Insulin; Lactates; Lactic Acid; Male; Muscles; Rats; Rats, Inbred Strains | 1983 |
Differential diagnosis of hypoglycemia in children by responses to fasting and 2-deoxyglucose.
Topics: 3-Hydroxybutyric Acid; Adolescent; Adult; Alanine; Blood Glucose; Child; Child, Preschool; Deoxy Sugars; Deoxyglucose; Diagnosis, Differential; Epinephrine; Fasting; Fatty Acids, Nonesterified; Female; Glucagon; Growth Hormone; Humans; Hydrocortisone; Hydroxybutyrates; Hypoglycemia; Infant; Insulin; Lactates; Lactic Acid; Male | 1983 |
Regulation of hexitol catabolism in Streptococcus mutans.
Topics: Biological Transport; Deoxy Sugars; Deoxyglucose; Enzyme Induction; Escherichia coli Proteins; Glucose; Lactates; Lactic Acid; Mannitol; Monosaccharide Transport Proteins; Phosphoenolpyruvate Sugar Phosphotransferase System; Sorbitol; Streptococcus mutans; Sugar Alcohol Dehydrogenases | 1983 |
Mechanism of reduction of action potential duration of ventricular myocardium by exogenous lactate.
Topics: Action Potentials; Animals; Coronary Disease; Deoxyglucose; Glucose; Glycogen; Glycolysis; Guinea Pigs; Lactates; Lactic Acid; Mannitol; Papillary Muscles | 1984 |
The action of (S)-alpha-chlorohydrin and 6-chloro-6-deoxyglucose on the metabolism of guinea pig spermatozoa.
Topics: alpha-Chlorohydrin; Animals; Chlorohydrins; Deoxy Sugars; Deoxyglucose; Fructose; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycolysis; Guinea Pigs; In Vitro Techniques; Lactates; Lactic Acid; Male; Spermatozoa; Stereoisomerism | 1984 |
Estimation of the rate of energy production of rat mast cells in vitro.
Topics: Adenosine Triphosphate; Animals; Antimycin A; Deoxyglucose; Energy Metabolism; In Vitro Techniques; Kinetics; Lactates; Lactic Acid; Male; Mast Cells; Oxidation-Reduction; Rats; Rats, Inbred Strains | 1983 |
Effects of valinomycin on hexose transport and cellular ATP pools in mouse fibroblasts.
Topics: 2,4-Dinitrophenol; 3-O-Methylglucose; Adenosine Triphosphate; Animals; Biological Transport, Active; Cells, Cultured; Deoxy Sugars; Deoxyglucose; Dinitrophenols; Fibroblasts; Iodoacetates; Iodoacetic Acid; Kinetics; Lactates; Lactic Acid; Methylglucosides; Methylglycosides; Mice; Potassium; Valinomycin | 1984 |
Transmural distribution of cardiac glucose uptake in rat during physical exercise.
Topics: Animals; Blood Glucose; Deoxyglucose; Fatty Acids, Nonesterified; Glucose; Glycogen; Heart Ventricles; Hemodynamics; Kinetics; Lactates; Lactic Acid; Male; Myocardium; Physical Exertion; Rats; Rats, Inbred Strains; Swimming; Tissue Distribution | 1983 |
Variations of glucose metabolism by fat cells from three adipose depots of the rat.
Topics: Adipose Tissue; Animals; Biological Transport, Active; Deoxyglucose; Epididymis; Glucose; Kinetics; Lactates; Lactic Acid; Lipolysis; Male; Organ Specificity; Peritoneum; Rats; Rats, Inbred Strains; Skin | 1982 |
Interrelationship between cellular metabolic status and susceptibility of heart cells to attack by phospholipase.
Topics: Adenosine Triphosphate; Animals; Antimetabolites; Cells, Cultured; Deoxyglucose; Energy Metabolism; Glycolysis; Heart; Lactates; Lactic Acid; Mitochondria; Myocardium; Oxygen Consumption; Phospholipases; Rats; Type C Phospholipases | 1982 |
The relationship between glycolysis, fatty acid metabolism and membrane integrity in neonatal myocytes.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Cell Membrane; Cells, Cultured; Deoxyglucose; Fatty Acids; Glycolysis; Iodoacetates; Iodoacetic Acid; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Myocardium; Oxidation-Reduction; Oxygen; Rats | 1981 |
The influence of ATP depletion on the action of phospholipase C on cardiac myocyte membrane phospholipids.
Topics: Adenosine Triphosphate; Animals; Cells, Cultured; Deoxyglucose; L-Lactate Dehydrogenase; Lactates; Lactic Acid; Membrane Lipids; Myocardium; Phospholipases; Phospholipids; Rats; Type C Phospholipases | 1981 |
Mutagenesis by 9-aminoacridine in Salmonella typhimurium: inhibition by glucose and other PTS class A carbon sources.
Topics: Aminacrine; Arabinose; Deoxyglucose; Glucose; Glycerol; Lactates; Lactic Acid; Methylglucosides; Mutagenesis; Phosphoenolpyruvate Sugar Phosphotransferase System; Salmonella typhimurium; Verapamil | 1994 |
Effects of glucosamine on insulin-stimulated glucose metabolism in rat soleus muscle.
Topics: Animals; Biological Transport; Deoxyglucose; Glucosamine; Glucose; Glycogen; Glycolysis; Insulin; Lactates; Lactic Acid; Male; Muscle, Skeletal; Phosphorylation; Radioligand Assay; Rats; Rats, Wistar; Stimulation, Chemical | 1995 |
Localised proton spectroscopy and spectroscopic imaging in cerebral gliomas, with comparison to positron emission tomography.
Topics: Aspartic Acid; Brain; Brain Chemistry; Brain Edema; Carbon Radioisotopes; Creatine; Deoxyglucose; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Glioma; Humans; Lactates; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Phosphorylcholine; Supratentorial Neoplasms; Tomography, Emission-Computed; Tyrosine | 1995 |
Transient rise of glucose uptake in the fetal rat brain after brief episodes of intrauterine ischemia.
Topics: Adenosine Triphosphate; Animals; Brain; Brain Chemistry; Brain Ischemia; Deoxyglucose; Energy Metabolism; Female; Glucose; Glycolysis; Kinetics; Lactates; Lactic Acid; Phosphocreatine; Placental Circulation; Pregnancy; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar; Reperfusion | 1994 |
Effect of the local anesthetic bupivacaine on the energy metabolism of Ehrlich ascites tumor cells.
Topics: Adenosine Triphosphate; Animals; Bupivacaine; Carcinoma, Ehrlich Tumor; Deoxyglucose; Electron Transport; Energy Metabolism; Glycolysis; Hexokinase; Lactates; Lactic Acid; Male; Mice; Mitochondria; NADP; Neoplasm Proteins; Oligomycins; Ouabain; Oxygen Consumption; Proton-Translocating ATPases; Tumor Cells, Cultured | 1994 |
Labeling of metabolic pools by [6-14C]glucose during K(+)-induced stimulation of glucose utilization in rat brain.
Topics: Animals; Autoradiography; Brain; Carbon Radioisotopes; Cerebral Cortex; Chromatography, High Pressure Liquid; Deoxyglucose; Glucose; Lactates; Lactic Acid; Male; Potassium; Potassium Chloride; Rats; Rats, Sprague-Dawley; Tissue Distribution | 1995 |
Heat-shock protein 70 mRNA is induced by anaerobic metabolism in rat hearts.
Topics: Anaerobiosis; Animals; Blotting, Northern; Creatine Kinase; Deoxyglucose; Gene Expression; HSP70 Heat-Shock Proteins; Lactates; Lactic Acid; Male; Myocardial Reperfusion Injury; Myocardium; Perfusion; Rats; Rats, Sprague-Dawley; RNA, Messenger; Time Factors | 1994 |
Endurance training fails to inhibit skeletal muscle glucose uptake during exercise.
Topics: Animals; Blood Glucose; Body Weight; Deoxyglucose; Female; Glucose; Glycogen; Lactates; Lactic Acid; Muscles; Physical Conditioning, Animal; Physical Endurance; Physical Exertion; Rats; Rats, Wistar | 1994 |
Different alterations in the insulin-stimulated glucose uptake in the athlete's heart and skeletal muscle.
Topics: Adult; Blood Glucose; Deoxyglucose; Echocardiography; Fluorodeoxyglucose F18; Glucose Clamp Technique; Heart; Humans; Insulin; Lactates; Lactic Acid; Male; Muscles; Myocardium; Physical Endurance; Sports; Tomography, Emission-Computed | 1994 |
Exercise-induced improvement in the sensitivity of the rat soleus muscle to insulin is reversed by chloroadenosine--the adenosine receptor agonist.
Topics: 2-Chloroadenosine; Animals; Deoxyglucose; Glucose; Glycogen; Glycolysis; Insulin; Lactates; Lactic Acid; Male; Muscles; Phosphorylation; Physical Conditioning, Animal; Rats; Rats, Wistar; Receptors, Purinergic | 1993 |
Studies with glycolysis-deficient cells suggest that production of lactic acid is not the only cause of tumor acidity.
Topics: Aerobiosis; Anaerobiosis; Animals; Biological Transport; Cell Division; Cell Line, Transformed; Cell Survival; Deoxyglucose; Genes, ras; Genetic Variation; Glycolysis; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Mice; Mice, Nude; Neoplasms, Experimental; Selection, Genetic | 1993 |
Inhibitors of glycolytic metabolism affect neurulation-staged mouse conceptuses in vitro.
Topics: Adenosine Triphosphate; Animals; Antimetabolites; Deoxyglucose; Embryo, Mammalian; Female; Glycolysis; Iodoacetates; Iodoacetic Acid; Lactates; Lactic Acid; Male; Mice; Mice, Inbred ICR; Nervous System; Neural Tube Defects; Organ Culture Techniques; Pregnancy; Tissue Distribution | 1995 |
Astrocyte glucose metabolism under normal and pathological conditions in vitro.
Topics: Acidosis; Adenosine Triphosphate; Animals; Astrocytes; Azides; Deoxyglucose; Drug Synergism; Glucose; Glycolysis; Hypoxia; Lactic Acid; Rats; Rats, Sprague-Dawley; Reference Values; Time Factors | 1996 |
Ethanol impairs insulin-mediated glucose uptake by an indirect mechanism.
Topics: Adult; Deoxyglucose; Diabetes Mellitus, Type 2; Ethanol; Fatty Acids, Nonesterified; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Forearm; Glucose; Humans; Insulin; Lactic Acid; Male; Middle Aged; Muscles; Osmolar Concentration; Reference Values; Triglycerides | 1996 |
Glucose transport and glucose transporter GLUT4 are regulated by product(s) of intermediary metabolism in cardiomyocytes.
Topics: 3-Hydroxybutyric Acid; 3-O-Methylglucose; Animals; Biological Transport; Cells, Cultured; Deoxyglucose; Diabetes Mellitus, Experimental; Energy Metabolism; Enzyme Inhibitors; Glucose; Glucose Transporter Type 1; Glucose Transporter Type 4; Hydroxybutyrates; Insulin; Lactic Acid; Monosaccharide Transport Proteins; Muscle Proteins; Myocardium; Phenylephrine; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Rats, Wistar; Substrate Specificity; Transaminases | 1997 |
Effects of glucocorticoid excess on the sensitivity of glucose transport and metabolism to insulin in rat skeletal muscle.
Topics: 3-O-Methylglucose; Animals; Blotting, Western; Deoxyglucose; Dexamethasone; Fructosediphosphates; Glucocorticoids; Glucose; Glucose Transporter Type 4; Glucose-6-Phosphate; Glycogen; Hexokinase; Insulin; Lactic Acid; Male; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Phosphorylation; Rats; Rats, Wistar | 1997 |
Effects of acute and chronic hindlimb suspension on sensitivity and responsiveness to insulin in the rat soleus muscle.
Topics: Animals; Deoxyglucose; Female; Glycogen; Hindlimb Suspension; Insulin; Lactic Acid; Muscle, Skeletal; Rats; Rats, Wistar | 1997 |
Lipoic acid reduces glycemia and increases muscle GLUT4 content in streptozotocin-diabetic rats.
Topics: Animals; Blood Glucose; Deoxyglucose; Diabetes Mellitus, Experimental; Glucose Transporter Type 4; In Vitro Techniques; Insulin; Lactic Acid; Male; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Rats; Rats, Sprague-Dawley; RNA, Messenger; Thioctic Acid | 1997 |
Histaminergic contribution to the metabolic effects of neuroglucopenia.
Topics: Alanine; Animals; Blood Glucose; Brain; Catecholamines; Deoxyglucose; Dogs; Female; Gluconeogenesis; Glucose; Glycerol; Histamine; Hormones; Injections, Intraventricular; Kinetics; Lactic Acid; Liver; Male | 1997 |
Effects of antitumor agents on 3H-2-deoxyglucose uptake in tumor cells and their relationship with the main targets of the antitumor agents.
Topics: 2,4-Dinitrophenol; Adenocarcinoma; Adenosine Triphosphate; Antineoplastic Agents; Cisplatin; Deoxyglucose; Doxorubicin; Drug Interactions; Guanosine; Humans; Iodoacetates; Iodoacetic Acid; Lactic Acid; Time Factors; Tumor Cells, Cultured | 1997 |
Sphingomyelinase increases 2-deoxyglucose uptake and glucose metabolism of human platelets.
Topics: Biological Transport; Blood Platelets; Deoxyglucose; Diffusion; Glycolysis; Humans; Kinetics; Lactic Acid; Sphingomyelin Phosphodiesterase; Thrombin | 1997 |
Increased choline signal coinciding with malignant degeneration of cerebral gliomas: a serial proton magnetic resonance spectroscopy imaging study.
Topics: Adult; Aged; Aspartic Acid; Biomarkers, Tumor; Biopsy; Brain Neoplasms; Cell Transformation, Neoplastic; Choline; Creatine; Deoxyglucose; Disease Progression; Female; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Follow-Up Studies; Glioma; Humans; Hydrogen; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neoplasm Recurrence, Local; Phosphocreatine; Prognosis; Protons; Radiopharmaceuticals; Tomography, Emission-Computed | 1997 |
Immune alterations in male and female mice after 2-deoxy-D-glucose administration.
Topics: Adjuvants, Immunologic; Animals; Antimetabolites; Blood Glucose; Cell Division; Cytokines; Deoxyglucose; Female; Flow Cytometry; Hormones; Immunity; Lactic Acid; Lymphocyte Activation; Lymphocyte Count; Lymphocytes; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA | 1997 |
The metabolic effects of pokeweed mitogen in mice.
Topics: Animals; B-Lymphocytes; Blood Glucose; Cell Line; Cytokines; Deoxyglucose; Diabetes Mellitus, Type 2; Eating; Insulin; Lactic Acid; Lipids; Male; Mice; Mice, Inbred Strains; Mice, SCID; Muscles; Obesity; Pokeweed Mitogens; T-Lymphocytes; Weight Loss | 1998 |
Investigation of the yeast mitochondrial unselective channel in intact and permeabilized spheroplasts.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Membrane Permeability; Cell Respiration; Deoxyglucose; Ion Channels; Lactic Acid; Mitochondria; NAD; Nystatin; Phosphates; Saccharomyces cerevisiae; Sorbitol; Spheroplasts; Triethyltin Compounds | 1998 |
Stimulation by hexose esters of lactate production by rat erythrocytes: insensitivity to 3-O-methyl-D-glucose and inhibition by 2-deoxy-D-glucose and its tetraacetic ester.
Topics: 3-O-Methylglucose; Animals; Deoxyglucose; Erythrocytes; Esters; Female; Galactose; Glucose; Hexoses; Lactic Acid; Mannoheptulose; Mannose; Rats; Rats, Wistar | 1998 |
Restoration of hypoxia-stimulated glucose uptake in GLUT4-deficient muscles by muscle-specific GLUT4 transgenic complementation.
Topics: Adenosine Triphosphate; Animals; Deoxyglucose; Female; Genetic Complementation Test; Glucose Transporter Type 4; Hypoxia; Lactic Acid; Male; Mice; Mice, Transgenic; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Myosin Light Chains; Phosphocreatine | 1998 |
Effects of 2-deoxy-D-glucose administration on immune parameters in mice.
Topics: Animals; Antimetabolites; B-Lymphocytes; Blood Glucose; Corticosterone; Deoxyglucose; Female; Lactic Acid; Lymphocyte Activation; Lymphocyte Subsets; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Spleen; T-Lymphocytes; Thymus Gland | 1998 |
Can experimental conditions explain the discrepancy over glutamate stimulation of aerobic glycolysis?
Topics: Aerobiosis; Animals; Astrocytes; Cells, Cultured; Culture Media; Deoxyglucose; Dose-Response Relationship, Drug; Glucose; Glucose-6-Phosphate; Glutamic Acid; Glycolysis; Lactic Acid; Mice; Osmolar Concentration; Rats | 1998 |
An increase in lactate output by brain tissue serves to meet the energy needs of glutamate-activated neurons.
Topics: Animals; Deoxyglucose; Energy Metabolism; Glutamic Acid; Glycolysis; Hippocampus; In Vitro Techniques; Lactic Acid; Male; Neurons; Rats; Rats, Sprague-Dawley | 1999 |
Feeding enhances extracellular lactate of local origin in the rostromedial hypothalamus but not in the cerebellum.
Topics: Animals; Blood Glucose; Cerebellum; Deoxyglucose; Eating; Extracellular Space; Glucose; Lactic Acid; Male; Microdialysis; Paraventricular Hypothalamic Nucleus; Postprandial Period; Rats; Rats, Wistar; Time Factors; Ventromedial Hypothalamic Nucleus | 1999 |
Reversal of permeability transition during recovery of hearts from ischemia and its enhancement by pyruvate.
Topics: Adenine Nucleotides; Animals; Capillary Permeability; Deoxyglucose; Hydrogen-Ion Concentration; In Vitro Techniques; Lactic Acid; Male; Mitochondria, Heart; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Osmolar Concentration; Pyruvic Acid; Rats; Rats, Wistar | 1999 |
Comparing effects of leptin and insulin on glucose metabolism in skeletal muscle: evidence for an effect of leptin on glucose uptake and decarboxylation.
Topics: Animals; Decarboxylation; Deoxyglucose; Glucose; Glycogen; Insulin; Lactic Acid; Leptin; Male; Muscle, Skeletal; Proteins; Rats; Rats, Wistar | 1999 |
Hyperlactatemia reduces muscle glucose uptake and GLUT-4 mRNA while increasing (E1alpha)PDH gene expression in rat.
Topics: Animals; Blood Glucose; Deoxyglucose; Gene Expression; Glucose; Glucose Clamp Technique; Glucose Transporter Type 4; Insulin; Insulin Resistance; Lactic Acid; Male; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Pyruvate Dehydrogenase Complex; Rats; Rats, Zucker; RNA, Messenger; Tritium | 1999 |
A factor from pancreatic and colonic cancer cells stimulates glucose uptake and lactate production in myoblasts.
Topics: Animals; Biological Factors; Cell Line; Colonic Neoplasms; Culture Media, Conditioned; Cycloheximide; Cytochalasin B; Deoxyglucose; Dose-Response Relationship, Drug; Endopeptidase K; Glucose; Glucose Transporter Type 4; Humans; Insulin; Lactic Acid; Molecular Weight; Monokines; Monosaccharide Transport Proteins; Muscle Proteins; Muscles; Pancreatic Neoplasms; Rats; Somatomedins; Tumor Cells, Cultured | 1999 |
Effect of tension on contraction-induced glucose transport in rat skeletal muscle.
Topics: Adenosine Triphosphate; Animals; Biological Transport; Cyclic AMP-Dependent Protein Kinases; Deoxyglucose; Electric Stimulation; Glucose; Glycogen; Lactic Acid; Male; Muscle Contraction; Muscle, Skeletal; Rats; Rats, Wistar | 1999 |
Intraventricular lactate infusion attenuates the transactivational effects of the glucose antimetabolite, 2-deoxy-D-glucose, on hypothalamic vasopressinergic neurons.
Topics: Animals; Deoxyglucose; Dose-Response Relationship, Drug; Glucose; Injections, Intraventricular; Lactic Acid; Male; Neurons; Paraventricular Hypothalamic Nucleus; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Supraoptic Nucleus; Vasopressins | 1999 |
The in vitro manipulation of carbohydrate metabolism: a new strategy for deciphering the cellular defence mechanisms against nitric oxide attack.
Topics: Adenosine Triphosphate; Carbohydrate Metabolism; Cell Survival; Culture Media; Deoxyglucose; Epithelial Cells; Galactose; Glucose; Glutathione; HT29 Cells; Humans; Lactic Acid; Nitric Oxide; Nitroso Compounds; Oligomycins; Pyruvic Acid; S-Nitrosoglutathione; Tyrosine | 1999 |
Effects of low oxygen concentrations and metabolic inhibitors on proteoglycan and protein synthesis rates in the intervertebral disc.
Topics: 2,4-Dinitrophenol; Animals; Cattle; Deoxyglucose; Intervertebral Disc; Lactic Acid; Oxygen; Oxygen Consumption; Proline; Protein Biosynthesis; Proteoglycans; Sulfates | 1999 |
Effect of exercise training on in vivo insulin-stimulated glucose uptake in intra-abdominal adipose tissue in rats.
Topics: Abdomen; Adipose Tissue; Animals; Blood Glucose; Body Water; Deoxyglucose; Female; Glucose; Insulin; Lactic Acid; Microdialysis; Physical Conditioning, Animal; Rats; Rats, Wistar; Regional Blood Flow | 2000 |
Relationship between motility and oxygen consumption of sperm from the cauda epididymides of the rat.
Topics: Acetates; Animals; Bucladesine; Deoxyglucose; Epididymis; Glucose; Kinetics; Lactic Acid; Male; Oxygen Consumption; Pyruvic Acid; Rats; Rats, Wistar; Sperm Motility; Spermatozoa | 1999 |
Examining glucose transport in single vascular smooth muscle cells with a fluorescent glucose analog.
Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Carotid Arteries; Cell Nucleus; Deoxyglucose; Fluorescent Dyes; Glucose; Image Processing, Computer-Assisted; Lactic Acid; Microscopy, Fluorescence; Muscle, Smooth, Vascular; Swine | 1999 |
Nitric oxide modifies glycolytic pathways in cultured human synoviocytes.
Topics: Cell Survival; Cells, Cultured; Deoxyglucose; Dose-Response Relationship, Drug; Glucose; Glyceraldehyde-3-Phosphate Dehydrogenases; Glycolysis; Hemoglobins; Humans; Lactic Acid; Nitric Oxide; Nitrites; Nitroprusside; Osteoarthritis; Penicillamine; S-Nitroso-N-Acetylpenicillamine; Synovial Membrane; Tritium | 2000 |
Effect of stimulation frequency on contraction-induced glucose transport in rat skeletal muscle.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adenylate Kinase; Animals; Biological Transport; Deoxyglucose; Electric Stimulation; Glucose; Glycogen; In Vitro Techniques; Inosine Monophosphate; Lactic Acid; Male; Muscle Contraction; Muscle, Skeletal; Phosphocreatine; Rats; Rats, Wistar; Reaction Time | 2000 |
Correction of hyperglycemia and insulin sensitivity by T-1095, an inhibitor of renal Na+-glucose cotransporters, in streptozotocin-induced diabetic rats.
Topics: Animals; Carbonates; Deoxyglucose; Diabetes Mellitus, Experimental; Glucosides; Hyperglycemia; Hypoglycemic Agents; In Vitro Techniques; Insulin Resistance; Lactic Acid; Male; Monosaccharide Transport Proteins; Muscle, Skeletal; Rats | 2000 |
Neuroprotective role of monocarboxylate transport during glucose deprivation in slice cultures of rat hippocampus.
Topics: Action Potentials; Animals; Anion Transport Proteins; Carrier Proteins; Cell Survival; Coumaric Acids; Deoxyglucose; Drug Combinations; Electrophysiology; Energy Metabolism; Glucose; Hippocampus; In Vitro Techniques; Lactic Acid; Neuroglia; Neurons; Rats; Rats, Wistar | 2001 |
Centrally injected atropine reduces hyperglycemia caused by 2-DG or immobilization stress in awake rats.
Topics: Animals; Antimetabolites; Atropine; Blood Glucose; Deoxyglucose; Hyperglycemia; Immobilization; Injections, Intraventricular; Lactic Acid; Male; Muscarinic Antagonists; Rats; Rats, Wistar; Stress, Psychological | 2001 |
Dynamic changes in glucose metabolism accompanying the expression of the neural phenotype after differentiation in PC12 cells.
Topics: Animals; Deoxyglucose; Fibroblasts; Glucose; Hexokinase; Humans; L-Lactate Dehydrogenase; Lactic Acid; Neurons; Oxidative Phosphorylation; PC12 Cells; Phenotype; Rats; Tumor Cells, Cultured | 2001 |
Suppression of the accumulation of triosephosphates and increased formation of methylglyoxal in human red blood cells during hyperglycaemia by thiamine in vitro.
Topics: Deoxyglucose; Diabetes Complications; Diabetes Mellitus; Erythrocytes; Glucose; Glycolysis; Humans; Hyperglycemia; Lactic Acid; Pentosephosphates; Pyruvaldehyde; Pyruvic Acid; Sugar Phosphates; Thiamine; Transketolase; Trioses | 2001 |
Inhibitory effect of hyperglycemia on insulin-induced Akt/protein kinase B activation in skeletal muscle.
Topics: Animals; Biological Transport; Deoxyglucose; Diabetes Mellitus, Experimental; Enzyme Activation; Glucose; Glucose Transporter Type 4; Hyperglycemia; Insulin; Intracellular Membranes; Lactic Acid; Male; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Oxidation-Reduction; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction | 2001 |
Hypersensitization of tumor cells to glycolytic inhibitors.
Topics: Anaerobiosis; Antimycin A; Culture Media; Deoxyglucose; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Enzyme Inhibitors; Glucose; Glycolysis; Growth Inhibitors; Humans; Lactic Acid; Oligomycins; Osteosarcoma; Oxamic Acid; Oxidative Phosphorylation; Rhodamine 123; Rotenone; Tumor Cells, Cultured; Uncoupling Agents | 2001 |
Hypoxia-induced upregulation of eNOS gene expression is redox-sensitive: a comparison between hypoxia and inhibitors of cell metabolism.
Topics: Animals; Antimetabolites; Cell Hypoxia; Cells, Cultured; Dactinomycin; Deoxyglucose; Dinitrophenols; Endothelium, Vascular; Humans; Immunoblotting; Lactic Acid; Niacin; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nucleic Acid Synthesis Inhibitors; Oxidation-Reduction; Oxygen; Promoter Regions, Genetic; Proto-Oncogene Proteins c-jun; RNA, Messenger; Rotenone; Swine; Transcription Factor AP-1; Uncoupling Agents; Up-Regulation | 2001 |
Effect of force development on contraction induced glucose transport in fast twitch rat muscle.
Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animals; Biological Transport; Deoxyglucose; Electric Stimulation; Glycogen; Lactic Acid; Male; Multienzyme Complexes; Muscle Contraction; Muscle Fibers, Fast-Twitch; Muscle, Skeletal; Protein Kinases; Protein Serine-Threonine Kinases; Rats; Rats, Wistar; Reaction Time | 2001 |
Heterogeneity in 2-deoxy-D-glucose-induced modifications in energetics and radiation responses of human tumor cell lines.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Carcinoma, Squamous Cell; Deoxyglucose; DNA Damage; DNA Repair; Energy Metabolism; Glioma; Glucose; Humans; Lactic Acid; Melanoma; Micronucleus Tests; Neoplasms; Radiation Dosage; Radiobiology; Tumor Cells, Cultured | 2001 |
Glucose catabolism in the rabbit VX2 tumor model for liver cancer: characterization and targeting hexokinase.
Topics: Animals; Antimetabolites; Antineoplastic Agents; Cell Survival; Deoxyglucose; Drug Delivery Systems; Enzyme Inhibitors; Glucose; Glycolysis; Hexokinase; Kinetics; Lactic Acid; Liver; Liver Neoplasms, Experimental; Phenotype; Pyruvates; Rabbits | 2001 |
Endothelin-1 stimulates cardiomyocyte injury during mitochondrial dysfunction in culture.
Topics: Animals; Buffers; Cell Survival; Cells, Cultured; Deoxyglucose; Endothelin-1; Heart; Hydrogen-Ion Concentration; Lactic Acid; Mitochondria; Rats; Rats, Sprague-Dawley; Rotenone | 2001 |
Intracellular redox status affects transplasma membrane electron transport in pulmonary arterial endothelial cells.
Topics: Animals; Cattle; Cell Membrane; Cells, Cultured; Deoxyglucose; Electron Transport; Endothelium, Vascular; Intracellular Membranes; Iodoacetates; Lactic Acid; NAD; Oxidation-Reduction; Pulmonary Artery | 2002 |
Tolbutamide alters glucose transport and metabolism in the embryonic mouse heart.
Topics: Animals; Culture Techniques; Deoxyglucose; Endoplasmic Reticulum Chaperone BiP; Female; Gene Expression; Glucose; Glucose Transporter Type 1; Glycolysis; Heart; Hexokinase; HSP70 Heat-Shock Proteins; Isotope Labeling; Lactic Acid; Male; Membrane Proteins; Mice; Monosaccharide Transport Proteins; RNA, Messenger; Teratogens; Tolbutamide | 2002 |
Glucose deprivation decreases nitric oxide production via NADPH depletion in immunostimulated rat primary astrocytes.
Topics: Adjuvants, Immunologic; Animals; Animals, Newborn; Astrocytes; Biopterins; Cell Death; Cells, Cultured; Central Nervous System; Deoxyglucose; Down-Regulation; Glucose; Glutathione; Interferon-gamma; Lactic Acid; Lipopolysaccharides; NADP; Neurodegenerative Diseases; Nitric Oxide; Nitric Oxide Synthase; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 2002 |
Effect of the ovarian hormones on GLUT4 expression and contraction-stimulated glucose uptake.
Topics: Animals; Deoxyglucose; Estradiol; Female; Glucose; Glucose Transporter Type 4; Glycogen; Insulin; Lactic Acid; Monosaccharide Transport Proteins; Muscle Contraction; Muscle Proteins; Muscle, Skeletal; Ovariectomy; Physical Exertion; Progesterone; Rats; Rats, Sprague-Dawley | 2002 |
Identification of lactate as a driving force for prostanoid transport by prostaglandin transporter PGT.
Topics: Antiporters; Biological Transport; Deoxyglucose; Dinoprostone; DNA-Binding Proteins; Dose-Response Relationship, Drug; Gene Expression; Glucose; Glutamine; Glycolysis; HeLa Cells; Humans; Lactic Acid; Organic Anion Transporters; Oxidative Phosphorylation; Prostaglandins; Transfection | 2002 |
Delayed changes in regional brain energy metabolism following cerebral concussion in rats.
Topics: Adenosine Triphosphate; Animals; Antimetabolites; Blood Glucose; Blood Pressure; Body Temperature; Brain Chemistry; Brain Concussion; Cerebral Cortex; Deoxyglucose; Energy Metabolism; Glucose; Glycogen; Hematocrit; Kinetics; Lactic Acid; Male; Oxygen; Phosphocreatine; Rats; Rats, Sprague-Dawley | 2002 |
Hypoxia increases tumor cell sensitivity to glycolytic inhibitors: a strategy for solid tumor therapy (Model C).
Topics: Antimetabolites; Cell Division; Cell Hypoxia; Deoxyglucose; Humans; Insect Repellents; Lactic Acid; Organic Chemicals; Oxygen; Tumor Cells, Cultured | 2002 |
How to balance the brain energy budget while spending glucose differently.
Topics: Adult; Animals; Brain; Deoxyglucose; Energy Metabolism; Glucose; Humans; Lactic Acid; Vagus Nerve | 2003 |
Uptake of locally applied deoxyglucose, glucose and lactate by axons and Schwann cells of rat vagus nerve.
Topics: Animals; Axons; Carbon Radioisotopes; Cinnamates; Deoxyglucose; Gap Junctions; Glucose; Lactic Acid; Male; Rats; Rats, Wistar; Schwann Cells; Tetrodotoxin; Vagus Nerve | 2003 |
Glial glutamate transporters mediate a functional metabolic crosstalk between neurons and astrocytes in the mouse developing cortex.
Topics: Amino Acid Transport System X-AG; Animals; Animals, Newborn; Aspartic Acid; Astrocytes; Blotting, Western; Cells, Cultured; Cerebral Cortex; Deoxyglucose; Efferent Pathways; Excitatory Amino Acid Transporter 2; Glycolysis; Immunohistochemistry; Lactic Acid; Mice; Mice, Inbred C57BL; Mice, Knockout; Neuroglia; Neurons; Physical Stimulation; Receptor Cross-Talk; Somatosensory Cortex; Synapses; Vibrissae | 2003 |
Effects of 2-deoxy-d-glucose on focal cerebral ischemia in hyperglycemic rats.
Topics: Animals; Antimetabolites; Aspartic Acid; Deoxyglucose; Hyperglycemia; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Protons; Rats; Rats, Sprague-Dawley | 2003 |
GABA uptake into astrocytes is not associated with significant metabolic cost: implications for brain imaging of inhibitory transmission.
Topics: Animals; Astrocytes; Biological Transport, Active; Brain; Cells, Cultured; Deoxyglucose; gamma-Aminobutyric Acid; Glutamic Acid; Intracellular Fluid; Lactic Acid; Magnesium; Mice; Nipecotic Acids; Pyridines; Sodium; Sodium-Potassium-Exchanging ATPase; Synaptic Transmission | 2003 |
Glucose deprivation produces a prolonged increase in sensitivity to glutamate in cultured rat cortical neurons.
Topics: Adenosine Triphosphate; Animals; Calcium; Cells, Cultured; Cerebral Cortex; Deoxyglucose; Dose-Response Relationship, Drug; Drug Resistance; Glucose; Glutamic Acid; Glycolysis; Lactic Acid; Mitochondria; Neurons; Oligomycins; Oxidative Phosphorylation; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Uncoupling Agents | 2003 |
Insulin stimulates glucose metabolism via the pentose phosphate pathway in Drosophila Kc cells.
Topics: 6-Aminonicotinamide; Animals; Carbon Dioxide; Carbon Radioisotopes; Cell Line; Deoxyglucose; Drosophila melanogaster; Glucose; Glycogen; Insulin; Lactic Acid; Pentose Phosphate Pathway; Tritium | 2003 |
The effect of hyperglycemia on experimental retinal ischemia.
Topics: Animals; Blood Glucose; Cyclophilins; Deoxyglucose; Diabetes Mellitus, Experimental; Electroretinography; Glucose; Hyperglycemia; Isotonic Solutions; Lactic Acid; Male; Rats; Rats, Wistar; Reperfusion Injury; Retina; Retinal Diseases; Retinal Vessels; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thy-1 Antigens; Vitreous Body | 2004 |
The regulation and importance of glucose uptake in the isolated Atlantic cod heart: rate-limiting steps and effects of hypoxia.
Topics: Analysis of Variance; Animals; Biological Transport, Active; Cytochalasin B; Deoxyglucose; Fishes; Glucose; Glucose-6-Phosphate; Glycogen; Heart; Hypoxia; Lactic Acid; Mannitol; Myocardium; Phlorhizin; Sodium; Time Factors | 2004 |
Effects of insulin-induced acute hypoglycemia and normoglycemic hyperinsulinemia on the retinal uptake and ocular metabolism of glucose in rabbits.
Topics: Animals; Biotransformation; Blood Glucose; Choroid; Deoxyglucose; Eye; Glucose; Glucose Clamp Technique; Hyperinsulinism; Hypoglycemia; Hypoglycemic Agents; Insulin; Lactic Acid; Male; Rabbits; Retina; Vitreous Body | 2004 |
Pyruvate protection against endothelial cytotoxicity induced by blockade of glucose uptake.
Topics: Animals; Antioxidants; Apoptosis; Cattle; Cell Survival; Cells, Cultured; Cytoprotection; Cytosol; Deoxyglucose; Dose-Response Relationship, Drug; Endothelium, Vascular; Glucose; Glutathione; Kinetics; Lactic Acid; Lipid Peroxidation; Pulmonary Artery; Pyruvic Acid; Thiobarbituric Acid Reactive Substances | 2004 |
Effects of pluronic P85 on GLUT1 and MCT1 transporters in the blood-brain barrier.
Topics: Animals; Antimetabolites; Blood-Brain Barrier; Blotting, Western; Cell Separation; Cells, Cultured; Deoxyglucose; Endothelium, Vascular; Excipients; Extracellular Space; Female; Glucose Transporter Type 1; Humans; Immunohistochemistry; Lactic Acid; Mice; Mice, Inbred C57BL; Monocarboxylic Acid Transporters; Monosaccharide Transport Proteins; Poloxalene; Symporters | 2004 |
Differential sensitivity to 2-deoxy-D-glucose between two pancreatic cell lines correlates with GLUT-1 expression.
Topics: Antimetabolites; Biomarkers, Tumor; Cell Line, Tumor; Deoxyglucose; Drug Resistance, Neoplasm; Excitatory Amino Acid Transporter 2; Glycolysis; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Lactic Acid; Mitochondria; Pancreatic Neoplasms | 2005 |
Effect of particle size of nanospheres and microspheres on the cellular-association and cytotoxicity of paclitaxel in 4T1 cells.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; Boron Compounds; Brain; Cattle; Cell Line, Tumor; Cell Survival; Chemistry, Pharmaceutical; Cyclosporine; Deoxyglucose; Drug Screening Assays, Antitumor; Endocytosis; Endothelium, Vascular; Etoposide; Lactic Acid; Microspheres; Nanotubes; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers | 2005 |
Cardiac metabolism in mice: tracer method developments and in vivo application revealing profound metabolic inflexibility in diabetes.
Topics: Animals; Blood Glucose; Body Weight; Butyrates; Carbon Radioisotopes; Deoxyglucose; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Genotype; Heart; Insulin; Lactic Acid; Mice; Mice, Inbred C57BL; Mice, Obese; Myocardium; Organ Size; Oxidation-Reduction; Receptors, Cell Surface; Receptors, Leptin; Triglycerides; Tritium | 2006 |
Efficacy of 2-halogen substituted D-glucose analogs in blocking glycolysis and killing "hypoxic tumor cells".
Topics: Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Cell Survival; Deoxyglucose; Drug Design; Fluorodeoxyglucose F18; Glucose-6-Phosphate; Glycolysis; Halogens; Hexokinase; Humans; Lactic Acid; Models, Molecular; Quantitative Structure-Activity Relationship; Thermodynamics | 2006 |
Differential metabolic adaptation to acute and long-term hypoxia in rat primary cortical astrocytes.
Topics: Adaptation, Physiological; Animals; Animals, Newborn; Astrocytes; Blotting, Western; Cell Hypoxia; Cell Size; Cell Survival; Cells, Cultured; Cerebral Cortex; Deoxyglucose; Glial Fibrillary Acidic Protein; Glucose; Immunohistochemistry; Lactic Acid; Phosphorylation; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Tritium | 2006 |
Effect of 2-deoxy-D-glucose on aminoacids metabolism in rats' cerebral cortex slices.
Topics: Animals; Carbon Dioxide; Carbon Radioisotopes; Cerebral Cortex; Deoxyglucose; Glucose; Glycine; In Vitro Techniques; Lactic Acid; Leucine; Lipids; Phosphorylation; Protein Biosynthesis; Rats; Rats, Wistar | 2006 |
Distinct effects of short- and long-term leptin treatment on glucose and fatty acid uptake and metabolism in HL-1 cardiomyocytes.
Topics: Animals; Carrier Proteins; CD36 Antigens; Cell Line; Deoxyglucose; Fatty Acid Transport Proteins; Fatty Acids; Glucose; Glycogen; Hypoglycemic Agents; Immunoblotting; Insulin; Lactic Acid; Leptin; Mice; Myocytes, Cardiac; Oxidation-Reduction; Receptors, Leptin; Recombinant Proteins; Tetrazolium Salts; Thiazoles | 2006 |
Differential mechanisms of radiosensitization by 2-deoxy-D-glucose in the monolayers and multicellular spheroids of a human glioma cell line.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Chromosome Aberrations; Cytochromes c; Deoxyglucose; DNA Repair; Glioma; Glucose; Humans; Lactic Acid; Mice; Proto-Oncogene Proteins c-bcl-2; Radiation-Sensitizing Agents; Reactive Oxygen Species; Spheroids, Cellular | 2006 |
The impact of hypoxia on in vivo glucose uptake in a hypoglycemic fish, Myoxocephalus scorpius.
Topics: Adenosine; Animals; Atropine; Blood Glucose; Brain Chemistry; Carbohydrate Metabolism; Cardiac Output; Deoxyglucose; Extracellular Fluid; Fishes; Glucose; Glucose-6-Phosphate; Heart Rate; Hypoxia; Lactic Acid; Muscarinic Antagonists; Phosphorylation; Purinergic P1 Receptor Antagonists; Theophylline; Tissue Distribution | 2007 |
Altered glucose metabolism in childhood pre-B acute lymphoblastic leukaemia.
Topics: Antigens, CD34; B-Lymphocytes; Cell Line, Tumor; Child; Citric Acid Cycle; Deoxyglucose; Gene Expression Profiling; Gene Expression Regulation, Leukemic; Glucose; Glucose Transporter Type 1; Glycolysis; Humans; Lactic Acid; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma; Precursor Cell Lymphoblastic Leukemia-Lymphoma; RNA, Messenger; Up-Regulation | 2006 |
Hypoxia-inducible factor-1 confers resistance to the glycolytic inhibitor 2-deoxy-D-glucose.
Topics: Adenosine Triphosphate; Antimetabolites; Apoptosis; Carcinoma, Hepatocellular; Cell Hypoxia; Deoxyglucose; Drug Resistance, Neoplasm; Glucose-6-Phosphate Isomerase; Glycolysis; HeLa Cells; Hexokinase; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immunoblotting; Lactic Acid; Liver Neoplasms; Plasmids; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transfection | 2007 |
Regulation of 2-deoxy-D-glucose transport, lactate metabolism, and MMP-2 secretion by the hypoxia mimetic cobalt chloride in articular chondrocytes.
Topics: Animals; Biological Transport, Active; Cartilage, Articular; Cells, Cultured; Chondrocytes; Cobalt; Deoxyglucose; Horses; Hypoxia; Lactic Acid; Matrix Metalloproteinase 2; Molecular Mimicry | 2006 |
Can radiation-induced apoptosis be modulated by inhibitors of energy metabolism?
Topics: Adenosine Triphosphate; Apoptosis; Deoxyglucose; Dose-Response Relationship, Radiation; Energy Metabolism; Enzyme Inhibitors; Glucose; Glycolysis; Humans; Lactic Acid; Luciferases; Radiation; Sodium Azide; Time Factors; U937 Cells | 2007 |
Glucose signaling controls the transcription of retrotransposon Ty2-917 in Saccharomyces cerevisiae.
Topics: Deoxyglucose; DNA-Binding Proteins; Ethanol; Fungal Proteins; Gene Deletion; Gene Expression Regulation, Fungal; Glucose; Glycerol; Lactic Acid; Retroelements; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction; Transcription Factors; Transcription, Genetic | 2007 |
Cyclic stretch of human lung cells induces an acidification and promotes bacterial growth.
Topics: Acidosis; Acidosis, Lactic; Antimetabolites; Cell Line; Cell Survival; Colony Count, Microbial; Culture Media, Conditioned; Cyclic AMP; Deoxyglucose; Dose-Response Relationship, Drug; Epithelial Cells; Escherichia coli K12; Formazans; Glucose; Humans; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Models, Biological; Ouabain; Oxamic Acid; Pneumonia, Ventilator-Associated; Pulmonary Alveoli; Respiration, Artificial; Sodium-Potassium-Exchanging ATPase; Stress, Mechanical; Time Factors | 2008 |
Berberine improves glucose metabolism through induction of glycolysis.
Topics: 3T3-L1 Cells; Adenosine Monophosphate; Adenosine Triphosphate; Adipocytes; AMP-Activated Protein Kinases; Animals; Berberine; Deoxyglucose; Diabetes Mellitus, Type 2; Drugs, Chinese Herbal; Glucose; Glucose Intolerance; Glycolysis; Insulin Resistance; Lactic Acid; Male; Mice; Mitochondria; Multienzyme Complexes; Obesity; Oxygen Consumption; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Rats, Wistar | 2008 |
Inhibition of monocarboxylate transporter 2 in the retrotrapezoid nucleus in rats: a test of the astrocyte-neuron lactate-shuttle hypothesis.
Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Astrocytes; Chemoreceptor Cells; Coumaric Acids; Deoxyglucose; Extracellular Fluid; Female; Hydrogen-Ion Concentration; In Vitro Techniques; Intracellular Membranes; Lactic Acid; Male; Medulla Oblongata; Models, Neurological; Monocarboxylic Acid Transporters; Neurons; Rats; Rats, Sprague-Dawley; Respiration | 2008 |
Ascorbic acid participates in a general mechanism for concerted glucose transport inhibition and lactate transport stimulation.
Topics: Animals; Ascorbic Acid; Biological Transport; Cell Line; Deoxyglucose; Epithelial Cells; Glucose; Glucose Transporter Type 1; Glucose Transporter Type 3; Hexokinase; Humans; Kinetics; Lactic Acid; Neurons; Organic Anion Transporters, Sodium-Dependent; Phosphorylation; Rats; Rats, Wistar; RNA, Messenger; Sodium-Coupled Vitamin C Transporters; Symporters | 2008 |
Metabolism-independent sugar sensing in central orexin neurons.
Topics: Acetylglucosamine; Alloxan; Animals; Carbohydrates; Deoxyglucose; Energy Metabolism; Fructose; Galactose; Glucosamine; Green Fluorescent Proteins; Hypothalamic Area, Lateral; Intracellular Signaling Peptides and Proteins; Lactic Acid; Mannose; Membrane Potentials; Methylglucosides; Mice; Mice, Transgenic; Neurons; Neuropeptides; Orexins; Patch-Clamp Techniques; Tolbutamide | 2008 |
Differential effects of in vivo and in vitro lactate treatments on liver carbohydrate metabolism of rainbow trout.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amino Acids; Animals; Blood Glucose; Carbohydrate Metabolism; Cinnamates; Deoxyglucose; Dichloroacetic Acid; Dose-Response Relationship, Drug; Glucokinase; Glycogen; Injections, Intraperitoneal; Lactate Dehydrogenases; Lactic Acid; Liver; Oncorhynchus mykiss; Sodium Chloride; Time Factors | 2008 |
Preferential utilization of NADPH as the endogenous electron donor for NAD(P)H:quinone oxidoreductase 1 (NQO1) in intact pulmonary arterial endothelial cells.
Topics: Androsterone; Animals; Cattle; Cells, Cultured; Cytosol; Deoxyglucose; Endothelial Cells; Glycolysis; Iodoacetates; Lactic Acid; NAD(P)H Dehydrogenase (Quinone); NADP; Oxidation-Reduction; Pulmonary Artery; Substrate Specificity | 2009 |
Neuronal glucose but not lactate utilization is positively correlated with NMDA-induced neurotransmission and fluctuations in cytosolic Ca2+ levels.
Topics: Animals; Antimetabolites; Aspartic Acid; Calcium; Calcium Signaling; Cells, Cultured; Cerebellum; Cytosol; Deoxyglucose; Excitatory Amino Acid Agonists; Glucose; Lactic Acid; Malates; Mice; N-Methylaspartate; Neurons; Neurotransmitter Agents; Synaptic Transmission | 2009 |
Acute changes in intermediary metabolism in cerebellum and contralateral hemisphere following middle cerebral artery occlusion in rat.
Topics: Acetates; Acute Disease; Amino Acids; Animals; Arterial Occlusive Diseases; Astrocytes; Brain Chemistry; Brain Ischemia; Cerebellum; Cerebral Cortex; Chromatography, High Pressure Liquid; Deoxyglucose; Electrophysiology; Functional Laterality; Glucose; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Middle Cerebral Artery; Neurotransmitter Agents; Rats; Rats, Wistar | 2009 |
Neuronal glucose transporter isoform 3 deficient mice demonstrate features of autism spectrum disorders.
Topics: Animals; Animals, Newborn; Behavior, Animal; Brain; Cell Adhesion Molecules, Neuronal; Child; Child Development Disorders, Pervasive; Deoxyglucose; Disease Models, Animal; Glucose Transporter Type 1; Glucose Transporter Type 3; Humans; Lactic Acid; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Monocarboxylic Acid Transporters; Nerve Tissue Proteins; Seizures; Vocalization, Animal | 2010 |
Ovarian carcinoma cells with low levels of beta-F1-ATPase are sensitive to combined platinum and 2-deoxy-D-glucose treatment.
Topics: Antimetabolites; Antineoplastic Agents; Apoptosis; Blotting, Western; Carboplatin; Cell Proliferation; Cisplatin; Deoxyglucose; Drug Resistance, Neoplasm; Drug Synergism; Female; Humans; Lactic Acid; Mitochondrial Proton-Translocating ATPases; Ovarian Neoplasms; Tumor Cells, Cultured | 2009 |
Molecular mechanisms involved in Sertoli cell adaptation to glucose deprivation.
Topics: Adaptation, Physiological; Animals; Blotting, Northern; Blotting, Western; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Deoxyglucose; Extracellular Space; Glucose; Glucose Transport Proteins, Facilitative; Glucose Transporter Type 1; Glucose Transporter Type 3; Lactic Acid; Male; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Rats; Rats, Sprague-Dawley; Sertoli Cells; Signal Transduction | 2009 |
Upregulation of lactate dehydrogenase A by ErbB2 through heat shock factor 1 promotes breast cancer cell glycolysis and growth.
Topics: Animals; Biological Transport; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Deoxyglucose; DNA-Binding Proteins; Down-Regulation; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glucose; Glycolysis; Heat Shock Transcription Factors; Humans; Isoenzymes; L-Lactate Dehydrogenase; Lactate Dehydrogenase 5; Lactic Acid; Oxamic Acid; Oxygen; Receptor, ErbB-2; RNA, Small Interfering; Transcription Factors; Transcriptional Activation; Up-Regulation | 2009 |
Ifosfamide metabolite chloroacetaldehyde inhibits cell proliferation and glucose metabolism without decreasing cellular ATP content in human breast cancer cells MCF-7.
Topics: Acetaldehyde; Adenosine Triphosphate; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Cell Survival; Deoxyglucose; Female; Glucose; Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating); Glycolysis; Hexokinase; Humans; Ifosfamide; Lactic Acid; Osmolar Concentration; Pyruvate Kinase | 2010 |
Pioglitazone modulates tumor cell metabolism and proliferation in multicellular tumor spheroids.
Topics: Cell Line, Tumor; Cell Proliferation; Chromans; Deoxyglucose; Humans; Hydrogen-Ion Concentration; Hypoglycemic Agents; Lactic Acid; Male; Pioglitazone; PPAR gamma; Prostatic Neoplasms; Spheroids, Cellular; Thiazolidinediones; Troglitazone | 2011 |
Energy metabolism of leukemia cells: glycolysis versus oxidative phosphorylation.
Topics: Antimetabolites; Cell Line, Tumor; Cell Proliferation; Deoxyglucose; Drug Resistance, Neoplasm; Energy Metabolism; Glucose; Glycolysis; HL-60 Cells; Humans; Lactic Acid; Leukemia; Oligomycins; Oxidative Phosphorylation; Uncoupling Agents | 2010 |
Evaluation of the impact of diabetes on retinal metabolites by NMR spectroscopy.
Topics: Animals; Blood Glucose; Deoxyglucose; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Glucose; Glycolysis; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Rats; Rats, Wistar; Retina | 2010 |
Glucose, not glutamine, is the dominant energy source required for proliferation and survival of head and neck squamous carcinoma cells.
Topics: Adenosine Triphosphate; Carcinoma; Carcinoma, Squamous Cell; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Chromatography, Liquid; Deoxyglucose; Disease Progression; Genes, p53; Glucose; Glutamine; Head and Neck Neoplasms; Humans; Lactic Acid; Mass Spectrometry; Metabolomics; Metformin; Neoplasms, Squamous Cell; Squamous Cell Carcinoma of Head and Neck; Treatment Outcome; Tumor Suppressor Protein p53 | 2011 |
Glucose is a pH-dependent motor for sperm beat frequency during early activation.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Carbonic Anhydrases; Cyclic AMP-Dependent Protein Kinases; Deoxyglucose; Energy Metabolism; Glucose; Hydrogen-Ion Concentration; Lactic Acid; Male; Methylamines; Mice; Mitochondria; NAD; NADP; Propionates; Pyruvic Acid; Sperm Motility; Spermatozoa; Succinic Acid | 2012 |
Higher transport and metabolism of glucose in astrocytes compared with neurons: a multiphoton study of hippocampal and cerebellar tissue slices.
Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Astrocytes; Biological Transport, Active; Biosensing Techniques; Blotting, Western; Cells, Cultured; Cerebellum; Deoxyglucose; Fluorescent Dyes; Glucose; Glucose Transporter Type 1; Glucose Transporter Type 3; Hippocampus; In Vitro Techniques; Lactic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Models, Statistical; Nerve Tissue Proteins; Neuroglia; Neurons | 2014 |
MEK1/2 inhibition decreases lactate in BRAF-driven human cancer cells.
Topics: Animals; Antineoplastic Agents; Benzamides; Benzimidazoles; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Deoxyglucose; Diphenylamine; Female; Gene Knockdown Techniques; Glucose; Hexokinase; Humans; Lactic Acid; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Melanoma; Mice; Mutation, Missense; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-myc; RNA, Small Interfering; Tumor Burden; Xenograft Model Antitumor Assays | 2013 |
Arsenic exposure induces the Warburg effect in cultured human cells.
Topics: Arsenites; Cell Line; Cells, Cultured; Deoxyglucose; Epithelial Cells; Extracellular Space; Gene Expression; Glycolysis; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Intracellular Space; Lactic Acid; Lung; Sodium Compounds | 2013 |
Inhibition of mTOR pathway sensitizes acute myeloid leukemia cells to aurora inhibitors by suppression of glycolytic metabolism.
Topics: Adaptor Proteins, Signal Transducing; Antineoplastic Agents; Aurora Kinases; Benzamides; Cell Line, Tumor; Deoxyglucose; Gene Expression Regulation, Neoplastic; Glucose; Glycolysis; HL-60 Cells; Humans; Indoles; Lactic Acid; Leukemia, Myeloid, Acute; Piperazines; Polyploidy; Purines; Quinazolines; Sequestosome-1 Protein; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases; U937 Cells | 2013 |
Mitochondrial function and energy metabolism in neuronal HT22 cells resistant to oxidative stress.
Topics: Animals; Calcium; Cell Count; Cell Death; Cell Respiration; Deoxyglucose; Drug Resistance; Energy Metabolism; Glucosephosphate Dehydrogenase; Glutamic Acid; Glutathione; Hexokinase; Hippocampus; Lactic Acid; Mechanistic Target of Rapamycin Complex 1; Mice; Mitochondria; Multiprotein Complexes; Neurons; Oligomycins; Oxidative Stress; Oxygen Consumption; Superoxides; TOR Serine-Threonine Kinases | 2014 |
Targeting cisplatin-resistant human tumor cells with metabolic inhibitors.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cisplatin; Deoxyglucose; Drug Resistance, Neoplasm; Female; Glycolysis; Hexokinase; Humans; Lactic Acid; Lung Neoplasms; Ovarian Neoplasms; RNA, Small Interfering; Transfection | 2014 |
Metabolism regulates the spontaneous firing of substantia nigra pars reticulata neurons via KATP and nonselective cation channels.
Topics: 3-Hydroxybutyric Acid; Action Potentials; Animals; Deoxyglucose; Female; GABAergic Neurons; Glycolysis; Iodoacetic Acid; KATP Channels; Lactic Acid; Male; Mice; Neurons; Pars Reticulata; Transient Receptor Potential Channels | 2014 |
MicroRNA-7 Promotes Glycolysis to Protect against 1-Methyl-4-phenylpyridinium-induced Cell Death.
Topics: 1-Methyl-4-phenylpyridinium; Adenosine Triphosphate; Animals; Cell Death; Cell Differentiation; Cell Line, Tumor; Cell Survival; Deoxyglucose; Glucose; Glucose Transporter Type 3; Glycolysis; HEK293 Cells; Humans; Lactic Acid; Mice; Mice, Inbred C57BL; MicroRNAs; Mitochondria; Neurons; Oxidative Phosphorylation; Oxygen; Parkinson Disease; Phosphorylation; Transcription Factor RelA | 2015 |
Synergism of ursolic acid derivative US597 with 2-deoxy-D-glucose to preferentially induce tumor cell death by dual-targeting of apoptosis and glycolysis.
Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Deoxyglucose; Drug Synergism; Female; G1 Phase Cell Cycle Checkpoints; Glucokinase; Glycolysis; HeLa Cells; Hep G2 Cells; Hexokinase; Humans; Lactic Acid; Liver Neoplasms; Membrane Potential, Mitochondrial; Mice; Neoplasm Transplantation; Triterpenes; Ursolic Acid | 2014 |
The anti-tumor efficacy of 2-deoxyglucose and D-allose are enhanced with p38 inhibition in pancreatic and ovarian cell lines.
Topics: Antineoplastic Agents; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Deoxyglucose; Dose-Response Relationship, Drug; Female; Genes, Reporter; Glucose; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Imidazoles; Lactic Acid; Ovarian Neoplasms; p38 Mitogen-Activated Protein Kinases; Pancreatic Neoplasms; Poly(ADP-ribose) Polymerases; Pyridines; Transcription, Genetic | 2015 |
2-Deoxy-d-Glucose Can Complement Doxorubicin and Sorafenib to Suppress the Growth of Papillary Thyroid Carcinoma Cells.
Topics: Adenosine Triphosphate; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Deoxyglucose; Dose-Response Relationship, Drug; Doxorubicin; Drug Combinations; Drug Synergism; Gene Expression; Glycolysis; Humans; Lactic Acid; Mutation; Niacinamide; Oxygen Consumption; Phenylurea Compounds; Proto-Oncogene Proteins B-raf; Sorafenib; Thyroid Gland | 2015 |
Enhancement of insulin-mediated rat muscle glucose uptake and microvascular perfusion by 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside.
Topics: Aminoimidazole Carboxamide; Animals; Blood Flow Velocity; Contrast Media; Deoxyglucose; Femoral Artery; Glucose Clamp Technique; Hindlimb; Hypoglycemic Agents; Insulin; Lactic Acid; Male; Microbubbles; Microcirculation; Microvessels; Muscle Fibers, Fast-Twitch; Muscle Fibers, Slow-Twitch; Muscle, Skeletal; Nitric Oxide Synthase; Rats, Wistar; Regional Blood Flow; Ribonucleotides; Time Factors; Ultrasonography | 2015 |
Adenosine A2B receptor activation stimulates glucose uptake in the mouse forebrain.
Topics: 4-Chloro-7-nitrobenzofurazan; Adenosine A2 Receptor Agonists; Animals; Astrocytes; Cells, Cultured; Deoxyglucose; Glucose; Hippocampus; In Vitro Techniques; Lactic Acid; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Prosencephalon; Receptor, Adenosine A2B | 2015 |
Lasting glycolytic stress governs susceptibility to urethane-induced lung carcinogenesis in vivo and in vitro.
Topics: Animals; Carcinogenesis; Carcinogens; Cell Line, Tumor; Deoxyglucose; Disease Models, Animal; Disease Susceptibility; DNA Damage; Electron Transport Complex IV; Female; Glycolysis; Humans; Lactic Acid; Lung; Lung Neoplasms; Metformin; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred ICR; Monocarboxylic Acid Transporters; Multienzyme Complexes; NADH, NADPH Oxidoreductases; Pyruvic Acid; Reactive Oxygen Species; Stress, Physiological; Symporters; Urethane | 2016 |
Enhancement of energy production by black ginger extract containing polymethoxy flavonoids in myocytes through improving glucose, lactic acid and lipid metabolism.
Topics: AMP-Activated Protein Kinases; Animals; Cell Line; Deoxyglucose; Energy Metabolism; Flavonoids; Glucose; Glucose Transporter Type 4; Lactic Acid; Lipid Metabolism; Lipolysis; Mice; Muscle, Skeletal; Obesity; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Phytotherapy; Plant Extracts; PPAR gamma; Thailand; Transcription Factors; Zingiber officinale; Zingiberaceae | 2016 |
Glucose Oxidation Is Critical for CD4+ T Cell Activation in a Mouse Model of Systemic Lupus Erythematosus.
Topics: Animals; Autoimmunity; CD4-Positive T-Lymphocytes; Cells, Cultured; Deoxyglucose; Dichloroacetic Acid; Disease Models, Animal; Energy Metabolism; Glucose; Interferon-gamma; Interleukin-17; Lactic Acid; Lupus Erythematosus, Systemic; Lymphocyte Activation; Metformin; Mice; Mice, Inbred C57BL; Mice, Transgenic; Oxidation-Reduction; Oxidative Phosphorylation; Oxygen Consumption; Pyruvic Acid | 2016 |
2-Deoxyglucose Reverses the Promoting Effect of Insulin on Colorectal Cancer Cells In Vitro.
Topics: Adenosine Triphosphate; Apoptosis; Cell Cycle; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Deoxyglucose; Flow Cytometry; Glycolysis; HCT116 Cells; Hexoses; Humans; Insulin; Lactic Acid; Neoplasm Invasiveness | 2016 |
Sleep fragmentation alters brain energy metabolism without modifying hippocampal electrophysiological response to novelty exposure.
Topics: Animals; Brain; Deoxyglucose; Disease Models, Animal; Electroencephalography; Energy Metabolism; Exploratory Behavior; Glycogen; Hippocampus; Lactic Acid; Male; Mice; Sleep; Sleep Deprivation; Time Factors | 2016 |
Novel insights into development of diabetic bladder disorder provided by metabolomic analysis of the rat nondiabetic and diabetic detrusor and urothelial layer.
Topics: Amino Acids, Branched-Chain; Animals; Bile Acids and Salts; Case-Control Studies; Citric Acid Cycle; Deoxyglucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Glucose; Glycation End Products, Advanced; Glycolysis; Hydroxybutyrates; Lactic Acid; Lipid Metabolism; Male; Metabolomics; Muscle, Smooth; Oxidation-Reduction; Oxidative Stress; Pentose Phosphate Pathway; Polymers; Prostaglandins; Rats; Rats, Inbred F344; Sorbitol; Urinary Bladder; Urinary Bladder Diseases; Urothelium | 2016 |
High rates of glucose utilization in the gas gland of Atlantic cod (Gadus morhua) are supported by GLUT1 and HK1b.
Topics: Animal Structures; Animals; Cell Separation; Cytochalasin B; Deoxyglucose; Erythrocytes; Gadus morhua; Gases; Glucose; Glucose Transporter Type 1; Hexokinase; Immunohistochemistry; Lactic Acid; Molecular Weight; Protein Transport; RNA, Messenger | 2016 |
EGF induces epithelial-mesenchymal transition and cancer stem-like cell properties in human oral cancer cells via promoting Warburg effect.
Topics: Aldehyde Dehydrogenase 1 Family; Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; CD24 Antigen; Cell Line, Tumor; Deoxyglucose; Dose-Response Relationship, Drug; Epidermal Growth Factor; Epithelial-Mesenchymal Transition; ErbB Receptors; Female; Glycolysis; Head and Neck Neoplasms; Humans; Hyaluronan Receptors; Hypoxia-Inducible Factor 1, alpha Subunit; Isoenzymes; Lactic Acid; Mice, Inbred BALB C; Mice, Nude; Mouth Neoplasms; Neoplastic Stem Cells; Phenotype; Phosphatidylinositol 3-Kinase; Polycomb Repressive Complex 1; Retinal Dehydrogenase; Signal Transduction; Squamous Cell Carcinoma of Head and Neck; Time Factors; Xenograft Model Antitumor Assays | 2017 |
Enhanced Glycolytic Metabolism Contributes to Cardiac Dysfunction in Polymicrobial Sepsis.
Topics: Animals; Cardiomyopathies; Cytokines; Deoxyglucose; Disease Models, Animal; Glycolysis; Heart; Hexokinase; Lactic Acid; Male; Mice; Mice, Inbred C57BL; Myocardium; Sepsis; Survival Analysis | 2017 |
Real-time monitoring system for evaluating the acid-producing activity of oral squamous cell carcinoma cells at different environmental pH.
Topics: Acids; Ammonia; Antimetabolites; Carcinoma, Squamous Cell; Cell Line; Cell Line, Tumor; Deoxyglucose; Glucose; Glutamic Acid; Glutamine; Humans; Hydrogen-Ion Concentration; Lactic Acid; Monitoring, Physiologic; Mouth Neoplasms | 2017 |
Lithium induces aerobic glycolysis and glutaminolysis in collecting duct principal cells.
Topics: Acetazolamide; Animals; Antimanic Agents; Aquaporin 2; Carbonic Anhydrase Inhibitors; Carbonic Anhydrase IX; Carbonic Anhydrases; Cell Line; Deoxyglucose; Diabetes Insipidus, Nephrogenic; Epithelial Sodium Channels; Female; Glutamine; Glycolysis; Kidney Tubules, Collecting; Lactic Acid; Lithium Chloride; Male; Mice; Mice, Inbred C57BL; Mice, Knockout | 2018 |
Suppression of oxidative phosphorylation confers resistance against bevacizumab in experimental glioma.
Topics: Animals; Antimetabolites; Antineoplastic Agents, Immunological; Bevacizumab; Brain Neoplasms; Cell Death; Cell Line, Tumor; Deoxyglucose; Drug Resistance, Neoplasm; Female; Gene Expression; Glioma; Glycolysis; Humans; Lactic Acid; Mice; Oxidative Phosphorylation; Oxygen Consumption; Xenograft Model Antitumor Assays | 2018 |
Metabolic reprogramming in keloid fibroblasts: Aerobic glycolysis and a novel therapeutic strategy.
Topics: Cell Proliferation; Cells, Cultured; Deoxyglucose; Fibroblasts; Gene Expression Regulation; Glucose; Glycolysis; Humans; Keloid; Lactic Acid; Oxygen Consumption; Skin | 2018 |
Radioresistant Cervical Cancers Are Sensitive to Inhibition of Glycolysis and Redox Metabolism.
Topics: Animals; Auranofin; Buthionine Sulfoximine; Cell Death; Cell Line, Tumor; Citric Acid Cycle; Deoxyglucose; Female; Glutathione; Glycolysis; Humans; Lactic Acid; Mice, Nude; Oxidation-Reduction; Radiation Tolerance; Reactive Oxygen Species; Thioredoxins; Uterine Cervical Neoplasms; Xenograft Model Antitumor Assays | 2018 |
Interferon Gamma Induces Reversible Metabolic Reprogramming of M1 Macrophages to Sustain Cell Viability and Pro-Inflammatory Activity.
Topics: Adenosine Triphosphate; Animals; Cell Differentiation; Cell Survival; Chemokines; Citric Acid Cycle; Deoxyglucose; Female; Galactose; Glycolysis; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Interferon-gamma; Janus Kinases; Lactic Acid; Macrophage Activation; Macrophages; Metabolome; Mice; Mitochondria; Nitric Oxide; Proto-Oncogene Proteins c-akt; Pyruvic Acid; RAW 264.7 Cells; Reactive Oxygen Species; Signal Transduction; STAT1 Transcription Factor | 2018 |
Perfluorocarbon Enhanced Glasgow Oxygen Level Dependent (GOLD) Magnetic Resonance Metabolic Imaging Identifies the Penumbra Following Acute Ischemic Stroke.
Topics: Animals; Autoradiography; Brain; Brain Ischemia; Brain Mapping; Carbon Radioisotopes; Contrast Media; Deoxyglucose; Disease Models, Animal; Fluorocarbons; Glucose; Humans; Hyperoxia; Infarction, Middle Cerebral Artery; Lactic Acid; Magnetic Resonance Imaging; Male; Oxygen; Rats; Rats, Sprague-Dawley; Stroke | 2018 |
Carvedilol prevents counterregulatory failure and impaired hypoglycaemia awareness in non-diabetic recurrently hypoglycaemic rats.
Topics: Adrenergic beta-1 Receptor Antagonists; Animals; Blood Glucose; Body Weight; Carvedilol; Catheterization; Deoxyglucose; Disease Models, Animal; Glucose Clamp Technique; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Insulin; Lactic Acid; Male; Rats; Rats, Sprague-Dawley; Recurrence; Time Factors; Ventromedial Hypothalamic Nucleus | 2019 |
Dietary 2-deoxy-D-glucose impairs tumour growth and metastasis by inhibiting angiogenesis.
Topics: Adenosine Diphosphate; Adenosine Triphosphate; Angiogenesis Inhibitors; Animals; Antimetabolites; Carcinoma, Lewis Lung; Cell Proliferation; Cell Survival; Deoxyglucose; Glucose; Glycolysis; Human Umbilical Vein Endothelial Cells; Humans; Lactic Acid; Lung Neoplasms; Mice; Neoplasm Metastasis; Neovascularization, Pathologic; Radiation, Ionizing; Vascular Endothelial Growth Factor A | 2019 |
Human herpesvirus 6A promotes glycolysis in infected T cells by activation of mTOR signaling.
Topics: Cell Line; Deoxyglucose; DNA Replication; DNA, Viral; Glucose; Glycolysis; Herpesvirus 6, Human; Humans; Lactic Acid; Mechanistic Target of Rapamycin Complex 1; Proto-Oncogene Proteins c-akt; Roseolovirus Infections; Signal Transduction; T-Lymphocytes; TOR Serine-Threonine Kinases; Viral Proteins; Virion | 2020 |
Lactic acid accumulation under heat stress related to accelerated glycolysis and mitochondrial dysfunction inhibits the mycelial growth of Pleurotus ostreatus.
Topics: Antimetabolites; Deoxyglucose; Glycolysis; Heat-Shock Response; Hot Temperature; Lactic Acid; Mitochondria; Mycelium; Pleurotus; Reactive Oxygen Species | 2020 |
Low-dose 2-deoxy glucose stabilises tolerogenic dendritic cells and generates potent in vivo immunosuppressive effects.
Topics: Animals; Antigens, Bacterial; Autoimmune Diseases; B7-2 Antigen; Bone Marrow Cells; CD4-Positive T-Lymphocytes; Cell Proliferation; Dendritic Cells; Deoxyglucose; Glycolysis; Histocompatibility Antigens Class II; Immunosuppressive Agents; Interleukin-10; Lactic Acid; Mice; Mice, Inbred C57BL; Oxidative Phosphorylation; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction | 2021 |
Metabolic reprogramming of osteoclasts represents a therapeutic target during the treatment of osteoporosis.
Topics: Animals; Antimetabolites; Bone Resorption; Cells, Cultured; Deoxyglucose; Female; Glycolysis; Lactic Acid; Mice; Mice, Inbred C57BL; Osteoclasts; Osteoporosis; Oxygen | 2020 |
Inhibition of aerobic glycolysis alleviates sepsis‑induced acute kidney injury by promoting lactate/Sirtuin 3/AMPK‑regulated autophagy.
Topics: Acute Kidney Injury; AMP-Activated Protein Kinases; Animals; Autophagy; Deoxyglucose; Glycolysis; Lactic Acid; Male; Mice; Mice, Inbred BALB C; Sepsis; Sirtuin 3 | 2021 |
Noradrenaline-induced l-lactate production requires d-glucose entry and transit through the glycogen shunt in single-cultured rat astrocytes.
Topics: Animals; Animals, Newborn; Arabinose; Astrocytes; Brain; Citric Acid Cycle; Deoxyglucose; Energy Metabolism; Fluorescence Resonance Energy Transfer; Glucose; Glycogen; Imino Furanoses; Lactic Acid; Nitro Compounds; Norepinephrine; Oxidative Phosphorylation; Primary Cell Culture; Propionates; Rats; Rats, Wistar; Sugar Alcohols; Transfection | 2021 |
Terazosin Stimulates Pgk1 to Remedy Gastrointestinal Disorders.
Topics: Apoptosis; Caco-2 Cells; Cell Survival; Colitis; Cytokines; Deoxyglucose; Dextran Sulfate; Gastric Mucosa; Gastrointestinal Diseases; Glucose; Humans; Hydrogen Peroxide; Inflammation Mediators; Lactic Acid; Malondialdehyde; Models, Biological; Peroxidase; Phosphoglycerate Kinase; Prazosin; Pyroptosis; Stomach Ulcer; Superoxide Dismutase | 2021 |
[Effects of blocking lactate production by 2-DG on hypoxic injury of HT22 neurons and its mechanisms].
Topics: Apoptosis; Deoxyglucose; Humans; Hypoxia; Lactic Acid; Neurons; Oxidative Stress; Reactive Oxygen Species; Superoxide Dismutase | 2022 |