Compounds > lactic acid

lactic acid and cyclosporine

lactic acid has been researched along with cyclosporine in 73 studies

Research

Studies (73)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's11 (15.07)18.2507
2000's25 (34.25)29.6817
2010's36 (49.32)24.3611
2020's1 (1.37)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Andrade, J; Bedoya, FJ; Conde, M; Santa Maria, C; Sobrino, F1
Conde, M; Gualberto, A; Sobrino, F1
Bedrossian, J; Eugène, M; Huneau, JF; Idatte, JM; Le Moyec, L; Pruna, A; Tomé, D1
Herman, B; Imberti, R; Lemasters, JJ; Nieminen, AL1
Apel, A; Cheng, YL; Chiu, R; Oh, C; Rootman, D; Saville, B1
Breitbart, H; Gruberger, M; Rubinstein, S1
Conde, M; Montaño, R; Moreno-Aurioles, VR; Ramirez, R; Sanchez-Madrid, F; Sanchez-Mateos, P; Sobrino, F1
Bouvet, JP; Giuliano, A; Marone, G; Patella, V1
Arimori, K; Nakano, H; Urata, T1
Aberturas, MR; Berges, L; Chacón, M; Guzmán, M; Molpeceres, J1
Capeans Tomé, C; Cuevas Alvarez, J; de Rojas Silva, MV; Lamas Díaz, MJ; Rodríguez-Ares, MT; Sánchez-Salorio, M; Vila Jato, JL1
Bal-Price, A; Brown, GC1
Aberturas, MR; Guzmán, M; Molpeceres, J; Saez, A1
Alonso, MJ; Calvo, P; Dellacherie, E; Gref, R; Quellec, P; Sanchez, A1
Koo, J; Kwon, S; Lee, S1
Bei, J; Shi, W; Wang, S; Wang, Z; Xie, L1
Wang, J; Zhang, Q1
Basu, S; Liu, XL; Nozari, A; Ronquist, G; Rubertsson, S; Wiklund, L1
Craig, DQ; Passerini, N1
Choi, K; Chung, DS; Kim, SH; Lee, WK; Park, JS; Park, JY; Suh, H; Yang, CW; Yang, EH1
Chee, SP; Lam, KW; Tan, D; Theng, JT; Ti, SE; Zhou, L1
Hao, YL; Ichimaru, A; Jiang, HL; Li, Y; Liu, JH; Yamamoto, K; Yasuda, H; Zhang, JX; Zhu, KJ1
De, S; Miller, DW; Robinson, DH1
He, Y; Liu, YL; Ma, ZZ; Wang, JC; Zhang, Q; Zhu, XA1
He, Y; Liu, Y; Lu, W; Ma, Z; Wang, J; Zhang, Q; Zhang, X; Zhu, X1
Jaafari, MR; Malaekeh-Nikouei, B; Sajadi Tabassi, SA2
Italia, JL; Ravi Kumar, MN; Sharma, G; Sonaje, K; Tikoo, K1
Bhardwaj, V; Italia, JL; Kumar, MN; Sharma, G; Sonaje, K; Tikoo, K1
Bullock, R; Gilman, C; Kunene, N; Mazzeo, A; Samuelson, R; Young, HF1
Bhardwaj, V; Bhatt, DK; Italia, JL; Kumar, MN; Tikoo, K1
Fernández, MA; González, M; Perazzo, JC; Prendes, MG; Savino, EA; Torresín, E; Varela, A1
Aten, J; de Boer, OJ; de Waart, DR; Hajji, N; Krediet, RT; Kunne, C; van Westrhenen, R1
Chaw, CS; Yeung, E1
Bei, J; Wang, S; Zhang, H1
Donovan, D; Evancho-Chapman, MM; Kanjickal, D; Lopina, S; Schmidt, S1
Habib, MJ; Khan, MA; Rahman, Z; Zidan, AS2
Jiang, W; Li, XR; Sun, HM; Tian, EJ; Wang, YQ; Yuan, JQ; Yuan, XB; Zhang, SX1
Hasenkam, JM; Kroyer, R; Lie, RH; Nielsen, TT; Sloth, E; Stoettrup, N1
Ankola, DD; Battisti, A; Kumar, MN; Solaro, R1
Fukata, N; Fukui, T; Koyabu, M; Kusuda, T; Matsushita, M; Miyoshi, H; Nishio, A; Okazaki, K; Tabata, Y; Uchida, K1
Hermans, K; Ludwig, A; Weyenberg, W1
Chudickova, M; Holan, V; Juklickova, M; Krulova, M; Kubinova, S; Michalek, J; Munzarova, M; Sirc, J; Svobodova, E; Sykova, E; Trosan, P; Zajicova, A1
Arpagaus, C; Douroumis, D; Jadhav, UY; Makne, S; Schafroth, N1
Aksungur, P; Demirbilek, M; Denkbaş, EB; Unlü, N1
Everaert, A; Hermans, K; Ludwig, A; Van den Plas, D; Weyenberg, W1
Bigam, DL; Brocks, DR; Chaudhary, H; Cheung, PY; Gill, RS; Lee, TF; Liu, JQ1
Balaskas, K; Eperon, S; Guex-Crosier, Y; Gurny, R; Rodriguez-Aller, M1
Caicco, MJ; Cooke, MJ; Morshead, CM; Shoichet, MS; Tuladhar, A; Wang, Y1
Bullock, MR; Gajavelli, S; Mazzeo, AT; Yokobori, S1
Hermans, K; Ludwig, A; Schreurs, E; Van Den Plas, D; Weyenberg, W1
Brennan, D; Galvin, P; Griffin, BT; Keohane, K1
Dutescu, RM; Merkel, OM; Panfil, C; Schrage, N1
Imura, H; Nitta, T; Shirakawa, M1
Cho, DW; Choi, YJ; Jang, J; Shim, JH; Song, TH1
Akter, S; Baik, HH; Beloor, J; Choi, TG; Ha, J; Jo, A; Jyothi, KR; Kang, I; Kim, JH; Kim, SS; Lee, SK; Maeng, CH; Nguyen, MN1
Dong, Z; Lei, Y; Li, T; Liu, L; Peng, X1
Morshead, CM; Shoichet, MS; Tuladhar, A1
Goyal, R; Kohn, J; Macri, L1
Bhardwaj, V; Ganju, L; Nehra, S; Saraswat, D1
de Almeida, FP; Fialho, SL; Jorge, R; Messias, A; Ribeiro, JA; Saliba, JB; Silva-Cunha, A; Siqueira, RC1
Egashira, K; Funamoto, D; Ikeda, G; Ishikita, A; Matoba, T; Nagaoka, K; Nakano, K; Nakano, Y; Sunagawa, K1
Bozdağ Pehlivan, S; Çakmak, HB; Çalamak, S; Kaffashi, A; Palaska, E; Ulubayram, K; Ünlü, N; Yavuz, B1
Dai, Z; Hong, J; Liu, X; Sun, J; Sun, X; Yu, X1
Ban, DX; Chang, J; Cheng, SZ; Feng, SQ; Gao, SJ; Liu, Y; Ning, GZ; Wang, HJ; Wang, LL1
Arora, M; Ganugula, R; Kumar, MN; Saini, P1
Arruebo, M; Larrea, A; Miana, M; Ortiz de Solorzano, I; Sebastian, V; Uson, L1
Arruebo, M; Benkirane-Jessel, N; Ferrandon, A; Idoux-Gillet, Y; Kuchler-Bopp, S; Larrea, A; Petry, L; Schwinté, P; Sebastian, V1
Carreras, JJ; Draheim, C; Garrigues, TM; Giner, E; Giner, R; Hansen, S; Lehr, CM; Melero, A; Peris, JE; Recio, MC; Talens-Visconti, R1
Bae, J; Im, E; Jung, Y; Kim, MS; Lee, BL; Moon, HR; Naeem, M; Oshi, MA; Yoo, JW1
Han, C; Jiang, YH; Li, W; Liu, Y1

Reviews

1 review(s) available for lactic acid and cyclosporine

ArticleYear
Mitochondrial neuroprotection in traumatic brain injury: rationale and therapeutic strategies.
    CNS & neurological disorders drug targets, 2014, Volume: 13, Issue:4

    Topics: Animals; Brain Injuries; Cyclosporine; Humans; Lactic Acid; Mitochondria; Neuroprotective Agents; Randomized Controlled Trials as Topic

2014

Other Studies

72 other study(ies) available for lactic acid and cyclosporine

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Inhibitory effect of cyclosporin A and FK506 on nitric oxide production by cultured macrophages. Evidence of a direct effect on nitric oxide synthase activity.
    Immunology, 1995, Volume: 84, Issue:3

    Topics: Amino Acid Oxidoreductases; Animals; Cells, Cultured; Cyclosporine; Dose-Response Relationship, Drug; Kinetics; Lactates; Lactic Acid; Macrophages, Peritoneal; Male; Mice; Mice, Inbred Strains; Nitric Oxide; Nitric Oxide Synthase; Pentose Phosphate Pathway; Tacrolimus

1995
Cyclosporin A antagonizes phenylephrine, oxytocin and angiotensin effects on glucose metabolism in rat thymus lymphocytes.
    Biochimica et biophysica acta, 1994, Mar-31, Volume: 1221, Issue:2

    Topics: Adenosine Triphosphate; Angiotensin II; Animals; Calcimycin; Cyclosporine; Dose-Response Relationship, Drug; Fructosediphosphates; Glucose; Glycolysis; Lactates; Lactic Acid; Lymphocytes; Male; Oxytocin; Phenylephrine; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate; Thymus Gland

1994
Proton nuclear magnetic resonance spectroscopy of urine and plasma in renal transplantation follow-up.
    Nephron, 1993, Volume: 65, Issue:3

    Topics: Alanine; Biomarkers; Blood Chemical Analysis; Citrates; Citric Acid; Creatinine; Cyclosporine; Dimethylamines; Graft Rejection; Humans; Kidney; Kidney Function Tests; Kidney Transplantation; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Methylamines; Urine

1993
Mitochondrial and glycolytic dysfunction in lethal injury to hepatocytes by t-butylhydroperoxide: protection by fructose, cyclosporin A and trifluoperazine.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 265, Issue:1

    Topics: Adenosine Triphosphate; Animals; Cell Survival; Cells, Cultured; Cyclosporine; Fructose; Glycolysis; Intracellular Membranes; Lactates; Lactic Acid; Liver; Male; Membrane Potentials; Mitochondria, Liver; Oligomycins; Oxidative Phosphorylation; Peroxides; Pyruvates; Pyruvic Acid; Rats; Rats, Sprague-Dawley; tert-Butylhydroperoxide; Trifluoperazine

1993
A subconjunctival degradable implant for cyclosporine delivery in corneal transplant therapy.
    Current eye research, 1995, Volume: 14, Issue:8

    Topics: Animals; Anterior Eye Segment; Biocompatible Materials; Biodegradation, Environmental; Conjunctiva; Cornea; Corneal Transplantation; Cyclosporine; Drug Delivery Systems; Drug Implants; Graft Rejection; Graft Survival; Lactic Acid; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rabbits

1995
Calcium efflux mechanism in sperm mitochondria.
    Biochimica et biophysica acta, 1996, Jun-13, Volume: 1312, Issue:2

    Topics: Adenosine Diphosphate; Animals; Atractyloside; Calcium; Calcium Channels; Calcium-Binding Proteins; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cyclosporine; Digitonin; Lactates; Lactic Acid; Male; Mersalyl; Mitochondria; Mitochondrial ADP, ATP Translocases; Phosphates; Ruthenium Red; Sheep; Spermatozoa; Uncoupling Agents

1996
Anti-CD69 antibodies enhance phorbol-dependent glucose metabolism and Ca2+ levels in human thymocytes. Antagonist effect of cyclosporin A.
    Journal of leukocyte biology, 1996, Volume: 60, Issue:2

    Topics: Antibodies, Monoclonal; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Calcium; Cyclosporine; Diglycerides; Drug Interactions; Fructosediphosphates; Glucose; Glycolysis; Humans; Immunosuppressive Agents; Lactates; Lactic Acid; Lectins, C-Type; Pyruvates; Pyruvic Acid; Signal Transduction; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Thymus Gland; Tritium

1996
Endogenous superallergen protein Fv induces IL-4 secretion from human Fc epsilon RI+ cells through interaction with the VH3 region of IgE.
    Journal of immunology (Baltimore, Md. : 1950), 1998, Nov-15, Volume: 161, Issue:10

    Topics: Adult; Allergens; Antibodies, Anti-Idiotypic; Basophils; Cyclosporine; Histamine Release; Humans; Immunoglobulin E; Immunoglobulin Heavy Chains; Immunoglobulin M; Immunoglobulin Variable Region; Interleukin-4; Kinetics; Lactic Acid; Lung; Lymphokines; Mast Cells; Myeloma Proteins; Receptors, IgE; RNA, Messenger; Sialoglycoproteins; Superantigens; Tacrolimus

1998
Modification of release rates of cyclosporin A from polyl(L-lactic acid) microspheres by fatty acid esters and in-vivo evaluation of the microspheres.
    Journal of controlled release : official journal of the Controlled Release Society, 1999, Mar-29, Volume: 58, Issue:2

    Topics: Animals; Arthritis, Experimental; Body Weight; Cyclosporine; Drug Delivery Systems; Fatty Acids; Hindlimb; Immunosuppressive Agents; Lactic Acid; Male; Microspheres; Particle Size; Polyesters; Polymers; Rats; Rats, Wistar

1999
Stability and freeze-drying of cyclosporine loaded poly(D,L lactide-glycolide) carriers.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 1999, Volume: 8, Issue:2

    Topics: Calorimetry, Differential Scanning; Chromatography, Gel; Cyclosporine; Drug Carriers; Drug Compounding; Drug Stability; Freeze Drying; Immunosuppressive Agents; Lactic Acid; Microspheres; Molecular Weight; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers

1999
Efficacy of subconjunctival cyclosporin-containing microspheres on keratoplasty rejection in the rabbit.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 1999, Volume: 237, Issue:10

    Topics: Animals; Aqueous Humor; Biocompatible Materials; Conjunctiva; Cornea; Corneal Transplantation; Cyclosporine; Disease Models, Animal; Drug Delivery Systems; Graft Rejection; Graft Survival; Immunosuppressive Agents; Injections; Lactic Acid; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rabbits; Radioimmunoassay; Treatment Outcome

1999
Nitric-oxide-induced necrosis and apoptosis in PC12 cells mediated by mitochondria.
    Journal of neurochemistry, 2000, Volume: 75, Issue:4

    Topics: Adenosine Triphosphate; Animals; Apoptosis; Azides; Caspase Inhibitors; Caspases; Cell Respiration; Cyclosporine; Cytochrome c Group; Cytosol; Enzyme Inhibitors; Glucose; Lactic Acid; Membrane Potentials; Methacrylates; Mitochondria; Necrosis; Nitric Oxide; Nitric Oxide Donors; Oxygen Consumption; PC12 Cells; Rats; Thiazoles

2000
Freeze-drying of polycaprolactone and poly(D,L-lactic-glycolic) nanoparticles induce minor particle size changes affecting the oral pharmacokinetics of loaded drugs.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2000, Volume: 50, Issue:3

    Topics: Administration, Oral; Animals; Biocompatible Materials; Biological Availability; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Cryoprotective Agents; Cyclosporine; Drug Carriers; Drug Stability; Entropy; Freeze Drying; Immunosuppressive Agents; Lactic Acid; Male; Particle Size; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rats; Rats, Wistar; Tissue Distribution

2000
Development and characterization of CyA-loaded poly(lactic acid)-poly(ethylene glycol)PEG micro- and nanoparticles. Comparison with conventional PLA particulate carriers.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2001, Volume: 51, Issue:2

    Topics: Cyclosporine; Diffusion; Drug Carriers; Drug Compounding; Humans; Immunosuppressive Agents; Lactates; Lactic Acid; Microscopy, Electron; Microspheres; Particle Size; Polyesters; Polyethylene Glycols; Polymers; Time Factors; Water

2001
Clinical spectrum of reversible posterior leukoencephalopathy syndrome.
    Pediatric neurology, 2001, Volume: 24, Issue:5

    Topics: Adolescent; Adult; Blood-Brain Barrier; Brain Edema; Child; Child, Preschool; Cyclosporine; Diagnosis, Differential; Female; Follow-Up Studies; Hemosiderin; Humans; Lactic Acid; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Neurologic Examination; Occipital Lobe; Parietal Lobe; Remission, Spontaneous; Risk Factors; Syndrome

2001
Prolongation of corneal allograft survival using cyclosporine in a polylactide-co-glycolide polymer.
    Cornea, 2001, Volume: 20, Issue:7

    Topics: Animals; Anterior Chamber; Aqueous Humor; Biological Availability; Cornea; Cyclosporine; Drug Delivery Systems; Female; Graft Survival; Keratoplasty, Penetrating; Lactic Acid; Male; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rats; Rats, Sprague-Dawley; Rats, Wistar; Transplantation, Homologous

2001
Uptake of cyclosporine A loaded colloidal drug carriers by mouse peritoneal macrophages in vitro.
    Acta pharmacologica Sinica, 2001, Volume: 22, Issue:1

    Topics: Animals; Capsules; Cell Separation; Cyclosporine; Drug Carriers; Emulsions; Female; Immunosuppressive Agents; Lactic Acid; Macrophages, Peritoneal; Male; Mice; Microspheres; Nanotechnology; Polyesters; Polymers

2001
Neurological outcome after experimental cardiopulmonary resuscitation: a result of delayed and potentially treatable neuronal injury?
    Acta anaesthesiologica Scandinavica, 2002, Volume: 46, Issue:5

    Topics: Angioplasty, Balloon, Coronary; Animals; Cardiopulmonary Resuscitation; Cerebrovascular Circulation; Cyclosporine; Dinoprost; Epinephrine; Free Radical Scavengers; Heart Arrest; Hypoxanthine; Lactic Acid; Nervous System Diseases; Saline Solution, Hypertonic; Swine; Treatment Outcome; Vasoconstrictor Agents; Vasopressins; Xanthine

2002
Characterization of ciclosporin A loaded poly (D,L lactide-co-glycolide) microspheres using modulated temperature differential scanning calorimetry.
    The Journal of pharmacy and pharmacology, 2002, Volume: 54, Issue:7

    Topics: Biocompatible Materials; Chemical Phenomena; Chemistry, Pharmaceutical; Chemistry, Physical; Cyclosporine; Delayed-Action Preparations; Drug Carriers; Drug Stability; Immunosuppressive Agents; Lactic Acid; Microscopy, Electron, Scanning; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Temperature

2002
Investigation of the factors influencing the release rates of cyclosporin A-loaded micro- and nanoparticles prepared by high-pressure homogenizer.
    Journal of controlled release : official journal of the Controlled Release Society, 2002, Dec-05, Volume: 84, Issue:3

    Topics: Cyclosporine; Drug Compounding; Kinetics; Lactic Acid; Microscopy, Electron, Scanning; Microspheres; Myristates; Nanotechnology; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Pressure; Solubility; Time Factors

2002
Pharmacokinetic and toxicity study of an intraocular cyclosporine DDS in the anterior segment of rabbit eyes.
    Investigative ophthalmology & visual science, 2003, Volume: 44, Issue:11

    Topics: Absorbable Implants; Animals; Anterior Eye Segment; Aqueous Humor; Biocompatible Materials; Biological Availability; Chromatography, High Pressure Liquid; Cornea; Cyclosporine; Drug Delivery Systems; Immunosuppressive Agents; Lactic Acid; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Prospective Studies; Rabbits; Safety

2003
In vitro and in vivo studies of cyclosporin A-loaded microspheres based on copolymers of lactide and epsilon-caprolactone: comparison with conventional PLGA microspheres.
    International journal of pharmaceutics, 2005, May-13, Volume: 295, Issue:1-2

    Topics: Animals; Cyclosporine; Lactic Acid; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rats; Rats, Wistar

2005
Effect of particle size of nanospheres and microspheres on the cellular-association and cytotoxicity of paclitaxel in 4T1 cells.
    Pharmaceutical research, 2005, Volume: 22, Issue:5

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; Boron Compounds; Brain; Cattle; Cell Line, Tumor; Cell Survival; Chemistry, Pharmaceutical; Cyclosporine; Deoxyglucose; Drug Screening Assays, Antitumor; Endocytosis; Endothelium, Vascular; Etoposide; Lactic Acid; Microspheres; Nanotubes; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers

2005
Therapeutic and toxicological evaluations of cyclosporine a microspheres as a treatment vehicle for uveitis in rabbits.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2006, Volume: 22, Issue:2

    Topics: Animals; Aqueous Humor; Biocompatible Materials; Cyclosporine; Disease Models, Animal; Drug Carriers; Electroretinography; Eye; Immunosuppressive Agents; Injections; Lactic Acid; Leukocyte Count; Leukocytes; Microspheres; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rabbits; Solubility; Uveitis

2006
Cyclosporine-loaded microspheres for treatment of uveitis: in vitro characterization and in vivo pharmacokinetic study.
    Investigative ophthalmology & visual science, 2006, Volume: 47, Issue:9

    Topics: Animals; Biocompatible Materials; Chromatography, High Pressure Liquid; Cyclosporine; Drug Carriers; Immunosuppressive Agents; Lactic Acid; Microscopy, Electron, Scanning; Microscopy, Phase-Contrast; Microspheres; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rabbits; Surface Properties; Uveitis; Vitreous Body

2006
The effect of different grades of PLGA on characteristics of microspheres encapsulated with cyclosporine A.
    Current drug delivery, 2006, Volume: 3, Issue:4

    Topics: Calorimetry, Differential Scanning; Capsules; Cyclosporine; Drug Carriers; Drug Compounding; Lactic Acid; Microscopy, Electron, Scanning; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Solubility; Spectrophotometry, Infrared

2006
Biodegradable in situ gelling system for subcutaneous administration of ellagic acid and ellagic acid loaded nanoparticles: evaluation of their antioxidant potential against cyclosporine induced nephrotoxicity in rats.
    Journal of controlled release : official journal of the Controlled Release Society, 2007, Mar-12, Volume: 118, Issue:1

    Topics: Animals; Antioxidants; Biological Availability; Chitosan; Cyclosporine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Ellagic Acid; Ethanolamines; Gels; Glycerol; Immunosuppressive Agents; Kidney; Kinetics; Lactic Acid; Male; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Propylene Glycol; Rats; Rats, Sprague-Dawley; Solvents; Temperature; Water

2007
Development of biodegradable nanoparticles for oral delivery of ellagic acid and evaluation of their antioxidant efficacy against cyclosporine A-induced nephrotoxicity in rats.
    Pharmaceutical research, 2007, Volume: 24, Issue:5

    Topics: Administration, Oral; Animals; Antioxidants; Biocompatible Materials; Biological Availability; Cyclosporine; Diffusion; Drug Compounding; Ellagic Acid; Immunosuppressive Agents; Kidney Diseases; Lactic Acid; Male; Microscopy, Polarization; Nanoparticles; Permeability; Polyesters; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Polyvinyl Alcohol; Rats; Rats, Sprague-Dawley; Treatment Outcome

2007
Synthes Award For Resident Research On Craniofacial And Brain Injury: effect of cyclosporin A, topiramate, or 100% oxygen as proposed "neuroprotective" therapies on the neurochemical analytes in patients with severe traumatic brain injury.
    Clinical neurosurgery, 2006, Volume: 53

    Topics: Adult; Awards and Prizes; Brain Injuries; Case-Control Studies; Cohort Studies; Cyclosporine; Fructose; Glucose; Glutamic Acid; Humans; Lactic Acid; Microdialysis; Neuroprotective Agents; Oxygen Inhalation Therapy; Pyruvic Acid; Topiramate

2006
PLGA nanoparticles for oral delivery of cyclosporine: nephrotoxicity and pharmacokinetic studies in comparison to Sandimmune Neoral.
    Journal of controlled release : official journal of the Controlled Release Society, 2007, Jun-04, Volume: 119, Issue:2

    Topics: Administration, Oral; Animals; Cyclosporine; Drug Delivery Systems; Kidney; Lactic Acid; Male; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rats; Rats, Sprague-Dawley

2007
Protection of ischaemic-reperfused rat heart by dimethylamiloride is associated with inhibition of mitochondrial permeability transition.
    Clinical and experimental pharmacology & physiology, 2008, Volume: 35, Issue:2

    Topics: Amiloride; Animals; Cardiovascular Agents; Cell Survival; Cyclosporine; Female; Glycolysis; In Vitro Techniques; Lactic Acid; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Membranes; Mitochondrial Permeability Transition Pore; Myocardial Reperfusion Injury; Myocytes, Cardiac; Perfusion; Permeability; Rats; Rats, Wistar; Sodium-Hydrogen Exchangers; Time Factors; Ventricular Function, Left; Ventricular Pressure

2008
Cyclosporin A induces peritoneal fibrosis and angiogenesis during chronic peritoneal exposure to a glucose-based, lactate-buffered dialysis solution in the rat.
    Blood purification, 2007, Volume: 25, Issue:5-6

    Topics: Animals; Cyclosporine; Fibrosis; Glucose; Hemodialysis Solutions; Lactic Acid; Male; Neovascularization, Pathologic; Peritoneal Dialysis; Peritoneal Diseases; Rats; Rats, Wistar

2007
Preparation, characterization, and mucoadhesive properties of chitosan-coated microspheres encapsulated with cyclosporine A.
    Drug development and industrial pharmacy, 2008, Volume: 34, Issue:5

    Topics: Adhesiveness; Cell Proliferation; Chemistry, Pharmaceutical; Chitosan; Chromatography, High Pressure Liquid; Cyclosporine; Drug Carriers; Drug Compounding; Humans; Immunosuppressive Agents; In Vitro Techniques; Lactic Acid; Microscopy, Electron, Scanning; Microspheres; Mucins; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solubility; Surface Properties; T-Lymphocytes

2008
Ciclosporin-loaded poly(lactide) microparticles: effect of TPGS.
    Journal of microencapsulation, 2009, Volume: 26, Issue:1

    Topics: Cyclosporine; Drug Carriers; Lactic Acid; Microspheres; Plasticizers; Polyesters; Polyethylene Glycols; Polymers; Solvents; Vitamin E

2009
Multi-morphological biodegradable PLGE nanoparticles and their drug release behavior.
    Biomaterials, 2009, Volume: 30, Issue:1

    Topics: Biocompatible Materials; Biodegradation, Environmental; Cyclosporine; Drug Delivery Systems; Lactic Acid; Molecular Weight; Nanoparticles; Nanotubes; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Spectrum Analysis; Time Factors

2009
Sustained local drug delivery from a novel polymeric ring to inhibit intimal hyperplasia.
    Journal of biomedical materials research. Part A, 2010, Volume: 93, Issue:2

    Topics: Absorbable Implants; Animals; Biocompatible Materials; Blood Vessels; Compressive Strength; Cyclosporine; Dogs; Drug Delivery Systems; Humans; Hyperplasia; Immunosuppressive Agents; Lactic Acid; Materials Testing; Microspheres; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Swine; Tunica Intima

2010
Spectral and spatial characterization of protein loaded PLGA nanoparticles.
    Journal of pharmaceutical sciences, 2010, Volume: 99, Issue:3

    Topics: Chemistry, Pharmaceutical; Cyclosporine; Drug Carriers; Drug Compounding; Emulsifying Agents; Lactic Acid; Models, Statistical; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Proteins; Solvents; Spectroscopy, Near-Infrared; Technology, Pharmaceutical

2010
[Combined rapamycin eye drop in nanometer vector and poly (lactic acid) wafers of cyclosporine A effectively prevents high-risk corneal allograft rejection in rabbits].
    [Zhonghua yan ke za zhi] Chinese journal of ophthalmology, 2009, Volume: 45, Issue:6

    Topics: Animals; Corneal Transplantation; Cyclosporine; Drug Delivery Systems; Graft Rejection; Immunosuppressive Agents; Lactic Acid; Nanoparticles; Polyesters; Polymers; Rabbits; Sirolimus

2009
Understanding the quality of protein loaded PLGA nanoparticles variability by Plackett-Burman design.
    International journal of pharmaceutics, 2010, Apr-15, Volume: 389, Issue:1-2

    Topics: Chemistry, Pharmaceutical; Cyclosporine; Delayed-Action Preparations; Diffusion; Drug Carriers; Emulsions; Excipients; Immunosuppressive Agents; Lactic Acid; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solubility; Solvents; Time Factors

2010
Post-conditioning with cyclosporine A fails to reduce the infarct size in an in vivo porcine model.
    Acta anaesthesiologica Scandinavica, 2010, Volume: 54, Issue:7

    Topics: Animals; Biomarkers; Coronary Circulation; Cyclosporine; Hemodynamics; Immunosuppressive Agents; Lactic Acid; Microdialysis; Myocardial Infarction; Myocardial Reperfusion Injury; Swine; Ventricular Fibrillation

2010
Nanoparticles made of multi-block copolymer of lactic acid and ethylene glycol containing periodic side-chain carboxyl groups for oral delivery of cyclosporine A.
    Journal of the Royal Society, Interface, 2010, Aug-06, Volume: 7 Suppl 4

    Topics: Animals; Biological Availability; Cyclosporine; Dosage Forms; Emulsions; Ethylene Glycol; Lactic Acid; Male; Molecular Weight; Nanoparticles; Particle Size; Polyglactin 910; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rats; Rats, Sprague-Dawley

2010
The effective therapy of cyclosporine A with drug delivery system in experimental colitis.
    Journal of drug targeting, 2011, Volume: 19, Issue:6

    Topics: Administration, Oral; Animals; Biocompatible Materials; Cell Line; Colitis; Cyclosporine; Cytokines; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Gene Expression; Immunosuppressive Agents; Lactic Acid; Macrophages; Mice; Mice, Inbred C57BL; Microspheres; Polyesters; Polymers; Tissue Distribution

2011
The effect of HPβCD on Cyclosporine A in-vitro release from PLGA nanoparticles.
    Journal of controlled release : official journal of the Controlled Release Society, 2010, Nov-20, Volume: 148, Issue:1

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; beta-Cyclodextrins; Cyclosporine; Lactic Acid; Magnetic Resonance Spectroscopy; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solubility

2010
Cyclosporine A-loaded and stem cell-seeded electrospun nanofibers for cell-based therapy and local immunosuppression.
    Journal of controlled release : official journal of the Controlled Release Society, 2011, Dec-20, Volume: 156, Issue:3

    Topics: Animals; Cell Proliferation; Cells, Cultured; Cyclosporine; Cytokines; Drug Carriers; Immunosuppressive Agents; Lactic Acid; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Nanofibers; Polyesters; Polymers; Skin Transplantation; T-Lymphocytes

2011
Nano and microparticle engineering of water insoluble drugs using a novel spray-drying process.
    Colloids and surfaces. B, Biointerfaces, 2012, Feb-01, Volume: 90

    Topics: Biocompatible Materials; Chemistry, Pharmaceutical; Cyclosporine; Delayed-Action Preparations; Desiccation; Dexamethasone; Drug Carriers; Drug Compounding; Hydrophobic and Hydrophilic Interactions; Kinetics; Lactic Acid; Molecular Weight; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Powders; Solubility; Solutions; Temperature; Water

2012
Comparative evaluation of cyclosporine A/HPβCD-incorporated PLGA nanoparticles for development of effective ocular preparations.
    Journal of microencapsulation, 2012, Volume: 29, Issue:6

    Topics: Administration, Ophthalmic; Animals; Cell Line; Cyclodextrins; Cyclosporine; Delayed-Action Preparations; Drug Evaluation, Preclinical; Lactic Acid; Mice; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solubility

2012
Full factorial design, physicochemical characterisation and biological assessment of cyclosporine A loaded cationic nanoparticles.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2012, Volume: 82, Issue:1

    Topics: Animals; Cations; Chitosan; Cyclosporine; Drug Carriers; Drug Compounding; Emulsions; Epithelial Cells; Humans; Immunosuppressive Agents; Jurkat Cells; Lactic Acid; Mucus; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solvents; Static Electricity; Swine; Tears

2012
Cyclosporine treatment reduces oxygen free radical generation and oxidative stress in the brain of hypoxia-reoxygenated newborn piglets.
    PloS one, 2012, Volume: 7, Issue:7

    Topics: Animals; Animals, Newborn; Blood Pressure; Carotid Arteries; Cerebral Cortex; Cyclosporine; Cytochromes c; Glutathione; Heart Rate; Hydrogen Peroxide; Hypoxia-Ischemia, Brain; Lactic Acid; Neuroprotective Agents; Oxidative Stress; Reactive Oxygen Species; Regional Blood Flow; Sus scrofa

2012
A new drug delivery system inhibits uveitis in an animal model after cataract surgery.
    International journal of pharmaceutics, 2013, Feb-25, Volume: 443, Issue:1-2

    Topics: Animals; Anti-Inflammatory Agents; Biocompatible Materials; Cataract Extraction; Cyclosporine; Disease Models, Animal; Drug Carriers; Drug Combinations; Drug Delivery Systems; Female; Lactic Acid; Lens Implantation, Intraocular; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rabbits; Triamcinolone Acetonide; Uveitis

2013
A hydrogel composite system for sustained epi-cortical delivery of Cyclosporin A to the brain for treatment of stroke.
    Journal of controlled release : official journal of the Controlled Release Society, 2013, Mar-28, Volume: 166, Issue:3

    Topics: Animals; Brain; Chromatography, Liquid; Cyclosporine; Delayed-Action Preparations; Drug Delivery Systems; Hyaluronic Acid; Hydrogels; Lactic Acid; Methylcellulose; Mice; Mice, Inbred C57BL; Microscopy, Electron, Scanning; Microspheres; Models, Biological; Neural Stem Cells; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solubility; Stroke; Surface Properties; Tandem Mass Spectrometry; Time Factors

2013
Cytotoxicity and anti-inflammatory activity of cyclosporine A loaded PLGA nanoparticles for ocular use.
    Die Pharmazie, 2014, Volume: 69, Issue:1

    Topics: Carcinogens; Cell Survival; Chromatography, High Pressure Liquid; Cyclosporine; Electrochemistry; Excipients; Freeze Drying; Humans; Interleukin-2; Jurkat Cells; Lactic Acid; Magnetic Resonance Spectroscopy; Nanoparticles; Ophthalmic Solutions; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Protective Agents; Solubility

2014
Silicon microfluidic flow focusing devices for the production of size-controlled PLGA based drug loaded microparticles.
    International journal of pharmaceutics, 2014, Jun-05, Volume: 467, Issue:1-2

    Topics: Chemistry, Pharmaceutical; Cyclosporine; Delayed-Action Preparations; Drug Carriers; Kinetics; Lactic Acid; Microfluidic Analytical Techniques; Particle Size; Polyethylene Glycols; Polyglactin 910; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Porosity; Silicon; Solubility; Surface Properties; Technology, Pharmaceutical

2014
Semifluorinated alkanes as a liquid drug carrier system for topical ocular drug delivery.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2014, Volume: 88, Issue:1

    Topics: Administration, Topical; Alkanes; Animals; Castor Oil; Cornea; Cyclosporine; Drug Carriers; Eye; Eye Diseases; Fluorescein; Fluorine; Glucose; Inflammation; Kinetics; Lactic Acid; Lipids; Rabbits; Solvents

2014
Propofol protects the immature rabbit heart against ischemia and reperfusion injury: impact on functional recovery and histopathological changes.
    BioMed research international, 2014, Volume: 2014

    Topics: Animals; Cyclosporine; Heart; Hemodynamics; Lactic Acid; Myocardium; Propofol; Protective Agents; Rabbits; Reperfusion Injury

2014
3D-Printed Drug/Cell Carrier Enabling Effective Release of Cyclosporin A for Xenogeneic Cell-Based Therapy.
    Cell transplantation, 2015, Volume: 24, Issue:12

    Topics: Animals; Cells, Cultured; Cyclosporine; Cytokines; Drug Carriers; Fibroblasts; Humans; Hydrogel, Polyethylene Glycol Dimethacrylate; Immunosuppressive Agents; Lactic Acid; Lung; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Printing, Three-Dimensional; Spleen; Transplantation, Heterologous

2015
Liver-targeted cyclosporine A-encapsulated poly (lactic-co-glycolic) acid nanoparticles inhibit hepatitis C virus replication.
    International journal of nanomedicine, 2015, Volume: 10

    Topics: Animals; Antiviral Agents; Cyclosporine; Disease Models, Animal; Hepacivirus; Hepatitis C; Lactic Acid; Liver; Mice; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Virus Replication

2015
Beneficial effect of cyclosporine A on traumatic hemorrhagic shock.
    The Journal of surgical research, 2015, May-15, Volume: 195, Issue:2

    Topics: Animals; Cyclosporine; Cytokines; Female; Hemodynamics; Hydrogen-Ion Concentration; Kidney; Lactic Acid; Liver; Male; Mitochondria; Protein Kinase C; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Shock, Hemorrhagic; Shock, Traumatic

2015
Circumventing the blood-brain barrier: Local delivery of cyclosporin A stimulates stem cells in stroke-injured rat brain.
    Journal of controlled release : official journal of the Controlled Release Society, 2015, Oct-10, Volume: 215

    Topics: Animals; Blood-Brain Barrier; Brain Infarction; Cell Count; Cyclosporine; Drug Compounding; Drug Delivery Systems; Hyaluronic Acid; Hydrogels; Immunosuppressive Agents; Lactic Acid; Lateral Ventricles; Male; Methylcellulose; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Long-Evans; Stem Cells; Stroke

2015
Formulation Strategy for the Delivery of Cyclosporine A: Comparison of Two Polymeric Nanospheres.
    Scientific reports, 2015, Aug-13, Volume: 5

    Topics: Chemistry, Pharmaceutical; Cyclosporine; Delayed-Action Preparations; Drug Stability; Emulsions; Hydrophobic and Hydrophilic Interactions; Kinetics; Lactic Acid; Nanocapsules; Nanospheres; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solubility; Solutions; X-Ray Diffraction

2015
Nanocurcumin Prevents Hypoxia Induced Stress in Primary Human Ventricular Cardiomyocytes by Maintaining Mitochondrial Homeostasis.
    PloS one, 2015, Volume: 10, Issue:9

    Topics: AMP-Activated Protein Kinases; Antioxidants; Cell Hypoxia; Cells, Cultured; Curcumin; Cyclosporine; Glucose; Glucose Transporter Type 1; Glucose Transporter Type 2; Heart Ventricles; Histone Acetyltransferases; Homeostasis; Humans; Lactic Acid; Membrane Potential, Mitochondrial; Mitochondria; Myocytes, Cardiac; Tumor Suppressor Protein p53

2015
In vivo release and retinal toxicity of cyclosporine-loaded intravitreal device.
    Documenta ophthalmologica. Advances in ophthalmology, 2015, Volume: 131, Issue:3

    Topics: Absorbable Implants; Animals; Chromatography, High Pressure Liquid; Cyclosporine; Drug Carriers; Drug Implants; Electroretinography; Immunosuppressive Agents; Lactic Acid; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rabbits; Retina; Vitreous Body

2015
Nanoparticle-Mediated Targeting of Cyclosporine A Enhances Cardioprotection Against Ischemia-Reperfusion Injury Through Inhibition of Mitochondrial Permeability Transition Pore Opening.
    Scientific reports, 2016, Feb-10, Volume: 6

    Topics: Animals; bcl-2-Associated X Protein; Cardiotonic Agents; Cells, Cultured; Cyclosporine; Cytochromes c; Disease Models, Animal; Drug Carriers; Hydrogen Peroxide; Lactic Acid; Male; Mice; Mice, Inbred C57BL; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Myocardial Reperfusion Injury; Myocytes, Cardiac; Nanoparticles; Oxidative Stress; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Ventricular Remodeling

2016
In vivo tissue distribution and efficacy studies for cyclosporin A loaded nano-decorated subconjunctival implants.
    Drug delivery, 2016, Volume: 23, Issue:9

    Topics: Absorbable Implants; Animals; Chemistry, Pharmaceutical; Cornea; Cyclosporine; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Lactic Acid; Male; Mice; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Tissue Distribution

2016
Development of a novel CsA-PLGA drug delivery system based on a glaucoma drainage device for the prevention of postoperative fibrosis.
    Materials science & engineering. C, Materials for biological applications, 2016, Sep-01, Volume: 66

    Topics: Animals; Cell Survival; Cells, Cultured; Chromatography, High Pressure Liquid; Cyclosporine; Drainage; Drug Carriers; Drug Liberation; Eye; Fibroblasts; Fibrosis; Fluorescein Angiography; Glaucoma; Immunohistochemistry; Intraocular Pressure; Lactic Acid; Microscopy, Electron, Scanning; Neovascularization, Physiologic; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rabbits; Thermogravimetry

2016
New approach to treating spinal cord injury using PEG-TAT-modified, cyclosporine-A-loaded PLGA/polymeric liposomes.
    Journal of drug targeting, 2017, Volume: 25, Issue:1

    Topics: Animals; Cyclosporine; Drug Carriers; Drug Liberation; Female; GAP-43 Protein; Gene Expression; Gene Products, tat; Lactic Acid; Liposomes; Nanoparticles; Nerve Regeneration; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats, Wistar; Spinal Cord; Spinal Cord Injuries

2017
The Next Generation Non-competitive Active Polyester Nanosystems for Transferrin Receptor-mediated Peroral Transport Utilizing Gambogic Acid as a Ligand.
    Scientific reports, 2016, 07-08, Volume: 6

    Topics: Administration, Oral; Animals; Biocompatible Materials; Biological Transport, Active; Caco-2 Cells; Cell-Free System; Cyclosporine; Humans; Intestines; Lactic Acid; Ligands; Male; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Receptors, Transferrin

2016
Continuous synthesis of drug-loaded nanoparticles using microchannel emulsification and numerical modeling: effect of passive mixing.
    International journal of nanomedicine, 2016, Volume: 11

    Topics: Computer Simulation; Cyclosporine; Emulsions; Hydrodynamics; Lactic Acid; Microfluidics; Nanoparticles; Numerical Analysis, Computer-Assisted; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer

2016
Promoting bioengineered tooth innervation using nanostructured and hybrid scaffolds.
    Acta biomaterialia, 2017, 03-01, Volume: 50

    Topics: Animals; Bioengineering; Cyclosporine; Dental Implants; Lactic Acid; Mice, Inbred ICR; Nanostructures; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Tissue Scaffolds; Tooth

2017
Targeted delivery of Cyclosporine A by polymeric nanocarriers improves the therapy of inflammatory bowel disease in a relevant mouse model.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2017, Volume: 119

    Topics: Administration, Oral; Animals; Biological Availability; Colon; Cyclosporine; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Inflammatory Bowel Diseases; Intestinal Mucosa; Lactic Acid; Mice; Mice, Inbred BALB C; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers

2017
Colon-targeted delivery of cyclosporine A using dual-functional Eudragit
    International journal of nanomedicine, 2018, Volume: 13

    Topics: Administration, Oral; Animals; Body Weight; Colitis; Colon; Cyclosporine; Cytokines; Drug Carriers; Drug Delivery Systems; Drug Liberation; Hydrogen-Ion Concentration; Immunosuppressive Agents; Inflammation Mediators; Lactic Acid; Macrophages; Methylmethacrylates; Mice, Inbred ICR; Nanoparticles; Particle Size; Peroxidase; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Treatment Outcome

2018
Astragalus membranaceus and Salvia miltiorrhiza ameliorates cyclosporin A-induced chronic nephrotoxicity through the "gut-kidney axis".
    Journal of ethnopharmacology, 2021, Apr-06, Volume: 269

    Topics: Animals; Astragalus propinquus; Butyric Acid; Colon; Cyclosporine; Drugs, Chinese Herbal; Endoplasmic Reticulum Stress; Fatty Acids; Fecal Microbiota Transplantation; Gastrointestinal Microbiome; Gene Expression Profiling; Gene Expression Regulation; Lactic Acid; Male; Medicine, Chinese Traditional; Mice, Inbred C57BL; MicroRNAs; Oxidative Stress; Receptors, Cell Surface; Renal Insufficiency, Chronic; RNA, Messenger; Salvia miltiorrhiza

2021