lactic acid has been researched along with chitosan in 523 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 4 (0.76) | 18.2507 |
2000's | 144 (27.53) | 29.6817 |
2010's | 343 (65.58) | 24.3611 |
2020's | 32 (6.12) | 2.80 |
Authors | Studies |
---|---|
Cohen, A; Maysinger, D; Mittal, S | 1 |
Liu, L; Song, Y; Xiong, M | 1 |
Frèche, M; Hatim, Z; Lacout, JL; Leroux, L | 1 |
Bégin, A; Van Calsteren, MR | 1 |
Kawashima, Y; Kuno, Y; Takeuchi, H; Yamamoto, H | 1 |
Kubis, AA; Małolepsza-Jarmołowska, K | 1 |
Hayashi, K; Ito, M; Kondo, Y; Nakatani, A | 1 |
Kawashima, Y; Takeuchi, H; Yamamoto, H | 1 |
Dyrset, N; Klinkenberg, G; Lystad, KQ | 1 |
Alonso, MJ; Calvo, P; Sánchez, A; Tobío, M; Vila, A | 1 |
Heimrath, J; Hirnle, G; Hirnle, L; Kłósek, A; Małolepsza-Jarmołowska, K; Woytoń, J | 1 |
Cai, K; Li, X; Li, Z; Yang, Z; Yao, K | 1 |
Cai, K; Li, F; Li, X; Liu, W; Xie, H; Yang, Z; Yao, K | 1 |
Shen, J; Wu, J; Zhang, M; Zhu, A | 1 |
Gao, C; Gong, Y; Ji, J; Ma, Z; Shen, J | 1 |
Conti, B; Genta, I; Modena, T; Pavanetto, F; Perugini, P | 1 |
Oh, SH | 1 |
Cui, YL; Liu, WG; Ma, DM; Qi, AD; Wang, H; Wang, XH; Yao, KD | 1 |
Nechaeva, E | 1 |
Bretzel, RG; Elçin, AE; Elçin, YM; Linn, T | 1 |
Ding, PT; Gao, P; Li, YJ; Pan, Y; Xu, H; Zheng, JM | 1 |
Ding, S; Li, L; Zhou, C | 1 |
Ho, MH; Hou, LT; Hsieh, HJ; Hsien, TY; Kuo, PY; Lai, JY; Wang, DM | 1 |
Cui, FZ; Feng, QL; Li, DP; Song, XH; Wang, WJ; Wang, XH; Xu, YX | 1 |
Chang, J; Chen, J; Ding, Z; Gao, S; Kang, ET; Zhang, J | 1 |
Bretzel, RG; Elçin, AE; Elçin, YM; Erb, D; Kidszun, A; Linn, T; Schneider, D | 1 |
Hu, KA; Liu, Y; Tian, F | 1 |
Park, SI; Zhao, Y | 1 |
Bodmer, D; Kissel, T; Weidenauer, U | 1 |
Aksungur, P; Iskit, AB; Senel, S; Squier, CA; Sungur, A; Unal, S | 1 |
Hellermann, G; Lockey, RF; Mohapatra, SS; Ravi Kumar, M | 1 |
Gao, JQ; Liang, WQ; Zhang, YP; Zheng, CH | 1 |
Gong, Y; Huang, C; Li, J; Li, P; Xie, G; Zhu, J | 1 |
Kawashima, Y; Kuno, Y; Sugimoto, S; Takeuchi, H; Yamamoto, H | 1 |
Dai, C; Wang, B; Zhao, H | 1 |
Gander, B; Luzardo-Alvarez, A; Merkle, HP | 1 |
Chen, WP; Chung, TW; Lee, CP; Liu, DZ; Wang, YC; Wu, SL | 1 |
Cao, Y; Cui, L; Liu, H; Mei, D; Yao, F; Yao, K; Zhou, Y | 1 |
Gupta, S; Jaganathan, KS; Jain, A; Prabakaran, D; Rao, YU; Singh, P; Vyas, SP | 1 |
Chen, D; Huang, C; Li, J; Li, Q; Xie, G; Zhu, J | 1 |
Chan-Park, MB; Zhu, AP | 1 |
Liang, WQ; Yu, HY; Zheng, CH | 1 |
Huang, CC; Huang, YC; Huang, YY; Liu, HC | 1 |
Bok, YB; Kum, KY; Lee, CY; Lee, DY; Spångberg, LS | 1 |
Funakoshi, T; Harada, K; Iwasaki, N; Majima, T; Minami, A; Nishimura, S; Sawaguchi, N; Shimode, K; Suenaga, N | 1 |
Altieri, C; Del Nobile, MA; Scrocco, C; Sinigaglia, M | 1 |
Guo, F; Huang, BY; Jian, XC; Pan, GF; Peng, JY; Xiong, CD; Xu, CJ | 1 |
Co, CC; Ho, CC; Yang, IH | 1 |
Goraltchouk, A; Morshead, CM; Scanga, V; Shoichet, MS | 1 |
Ellenberger, S; Fischer, S; Foerg, C; Gander, B; Merkle, HP | 1 |
Jaganathan, KS; Vyas, SP | 1 |
Gao, JQ; Liang, WQ; Wang, Y; Xu, DH; Zheng, CH | 1 |
Atilla Hincal, A; Calis, S; Samdancioglu, S; Sumnu, M | 1 |
Depan, D; Kumar, AP; Singh, RP | 2 |
Cooper-White, JJ; Croll, TI; O'Connor, AJ; Stevens, GW | 1 |
Abdel-Fattah, WI; Jiang, T; Laurencin, CT | 1 |
Liu, Y; Pang, J; Su, L; Wu, B; Wu, H; Yang, T; Zhao, H | 1 |
Borchert, HH; Lorenzen, DR; Siebenbrodt, I; Wischke, C; Zimmermann, J | 1 |
Madihally, SV; Moshfeghian, A; Tillman, J | 1 |
Chen, HL; Gao, JQ; Han, G; Liang, WQ; Sun, XY | 1 |
Gao, QP; Guo, F; Jian, XC; Peng, JY; Wu, YF; Xu, CJ | 1 |
Małolepsza-Jarmołowska, K | 1 |
de Saja, JA; Mano, JF; Prabaharan, M; Rodriguez-Perez, MA | 1 |
Apirakaramwong, A; Ngawhirunpat, T; Opanasopit, P; Rojanarata, T; Weecharangsan, W | 1 |
Jiao, Y; Liu, Z; Zhou, C | 1 |
Hirnle, L; Hirnle, P; Kubis, AA; Małolepsza-Jarmołowska, K | 1 |
Italia, JL; Ravi Kumar, MN; Sharma, G; Sonaje, K; Tikoo, K | 1 |
Duan, B; Li, X; Wu, L; Yao, K; Yuan, X; Zhang, Y | 1 |
Bonferoni, MC; Caramella, C; Giunchedi, P; Rossi, S; Sandri, G; Scalia, S | 1 |
Chen, KS; Huang, CC; Huang, YC; Huang, YY | 1 |
Lee, ES; Na, K; Park, IS; Park, KH | 1 |
Cui, X; Li, CM; Yu, S; Zang, J | 1 |
Cheepsunthorn, P; Chuenjitbuntaworn, B; Pavasant, P; Sangsanoh, P; Supaphol, P; Suwantong, O; Waleetorncheepsawat, S; Weeranantanapan, O; Wutticharoenmongkol, P | 1 |
Chen, J; Hou, C; Hu, D; Hu, Z; Li, H; Liu, M; Pan, Y; Tian, B; Wang, J; Yin, X; Zhang, Y; Zhao, J | 1 |
Guan, XP; Liao, KR; Mai, KC; Quan, DP | 1 |
Nie, H; Wang, CH | 1 |
Cai, K; Li, X; Qu, Y; Yang, Z; Yao, K | 1 |
Hsu, SH; Lu, PS; Ni, HC; Su, CH | 1 |
Duan, B; Hu, Z; Li, X; Wang, M; Wu, L; Yao, K; Yuan, X; Zhang, Y | 1 |
Jiao, Y; Liu, Z; Zhang, Z; Zhou, C | 1 |
Lee, JY; Lee, MC; Lee, SH; Lee, SJ; Lee, SY; Park, YJ; Shim, IK | 1 |
Cai, K; Hu, Y; Wang, Y; Yang, L | 1 |
Alpar, HO; Cevher, E; Pandit, S; Somavarapu, S; Zariwala, MG | 1 |
Budhian, A; Siegel, SJ; Winey, KI | 1 |
Lehr, CM; Nafee, N; Schaefer, UF; Schneider, M; Taetz, S | 1 |
Guo, F; Xian, X; Xu, C | 1 |
Bhattarai, N; Chou, SH; Ramay, HR; Zhang, M | 1 |
Kawashima, Y; Tahara, K; Takeuchi, H; Yamamoto, H | 1 |
Huang, DH; Jiang, W; Li, H; Liu, J; Sheng, J; Shun, HM; Tian, EJ; Yuan, XB; Yuan, XY; Yuan, YB | 1 |
Chung, TW; Tsai, WJ; Wang, SS | 1 |
Cho, BC; Choi, JH; Chung, HY; Jeon, YH; Kim, TK; Sung, JK | 1 |
Antimisiaris, SG; Dracopoulos, V; Fadda, AM; Manca, ML; Mourtas, S | 1 |
Kawashima, Y; Sakai, T; Tahara, K; Takeuchi, H; Yamamoto, H | 1 |
Campbell, GR; Campbell, JH; Cao, Y; Cooper-White, JJ; Croll, T; Martin, D; Rolfe, BE; Zhang, B | 1 |
Andersen, MØ; Besenbacher, F; Bünger, C; Foss, M; Howard, KA; Kjems, J; Nygaard, JV | 1 |
Lawrence, BJ; Lin, HK; Maase, EL; Madihally, SV | 1 |
Cao, X; Wan, Y; Wang, S; Wu, Q; Zhang, S | 1 |
Araújo, AB; Ferreira, JM; Lemos, AF | 1 |
Gao, J; Li, H; Meng, X; Qu, L; Wang, J; Wen, G | 1 |
Cho, KS; Choi, SH; Jung, UW; Kim, CK; Kim, CS; Lee, YK; Song, KY | 1 |
Choi, JH; Joung, YK; Park, KD; Park, KM | 1 |
Du, LQ; Li, MC; Pang, KP; Wang, SG; Wu, XY | 1 |
Cevher, E; Chen, S; Katas, H; Osamuyimen, AA; Oya Alpar, H | 1 |
Jaafari, MR; Malaekeh-Nikouei, B; Sajadi Tabassi, SA | 1 |
Espuelas, MS; Gamazo, C; Gómez, S; Irache, JM; San Román, B; Tsapis, N | 1 |
Lee, LY; Nie, H; Tong, H; Wang, CH | 1 |
Larsen, G; Leonov, AP; Noriega, S; Skotak, M; Subramanian, A | 1 |
Gemeinhart, RA; Guo, C | 1 |
Nayak, B; Panda, AK; Ray, AR; Ray, P | 1 |
Chung, CP; Ku, Y; Lee, JY; Lee, SJ; Nam, SH; Park, JB; Park, YJ; Rhee, SH; Shim, IK | 1 |
Gu, B; Li, QF; Liu, K; Shen, GX; Xie, F | 1 |
Chen, H; Liu, L; Yuan, P; Zhang, Q | 1 |
Cheng, G; Chung, SJ; Cui, F; Kim, DD; Kim, IW; Shim, CK; Shim, WS; Yang, R; Yang, SG | 1 |
Cheng, X; Peng, L; Shi, S; Wang, J; Zhang, W; Zhang, Y | 1 |
Jin, L; Liu, L; Wang, X; Xiong, Z; Yan, Y; Zhang, R | 1 |
Baldes, C; Beisner, J; Huwer, H; Klotz, U; Lehr, CM; Mürdter, TE; Nafee, N; Piotrowska, K; Schaefer, UF; Schneider, M; Taetz, S | 1 |
Bonferoni, MC; Caramella, C; Ferrari, F; Marciello, M; Rossi, S; Sandri, G | 1 |
Gao, C; Lao, L; Tan, H; Wu, J | 1 |
Kim, BS; Kim, CS; Lee, KM | 1 |
Antimisiaris, SG; Fadda, AM; Loy, G; Manca, ML; Zaru, M | 1 |
Ignatova, M; Manolova, N; Markova, N; Rashkov, I | 1 |
Cui, Z; Jiang, B; Liu, T; Ma, X; Song, K; Zhu, Y | 1 |
Iyer, P; Madihally, SV; Mirani, RD; Pratt, J | 1 |
Chou, NK; Chung, TW; Wang, SS | 1 |
Feng, Q; Guo, X; Niu, X; Wang, M; Zheng, Q | 1 |
Cheng, G; Chung, SJ; Cui, FD; Han, X; Jin, QR; Kim, DD; Shim, CK; Shim, WS; Yang, R | 1 |
Li, H; Li, S; Li, X; Wu, L; Yuan, X; Zhang, Y | 1 |
Ma, T; Zhao, F; Zhu, A | 1 |
Cai, X; Chen, W; Hu, J; Shen, X; Tong, H; Yan, J | 1 |
Hasirci, N; Hasirci, V; Reis, RL; Tuzlakoglu, K; Yilgor, P | 1 |
Martínez-Castellanos, G; Pelayo-Zaldívar, C; Pérez-Flores, LJ; Sepúlveda-Sánchez, JD; Shirai, K | 1 |
Chen, G; Gao, JQ; He, CX; Liu, L; Xu, DH; Xu, JY; Yan, M; Zhang, FJ; Zheng, CH | 1 |
Lehr, CM; Nafee, N; Schaefer, UF; Schneider, M | 1 |
He, CL; Hu, W; Huang, ZM; Meng, SY | 1 |
Burt, H; Ghahary, A; Jackson, J; Rahmani-Neishaboor, E | 1 |
Burrows, JL; French, E; Learoyd, TP; Seville, PC | 1 |
Chen, H; Gao, F; Jiang, Q; Liu, L; Wang, Y; Yang, W; Yang, X; Zhang, Q | 1 |
Li, S; Wan, T; Xu, H; Yan, Y | 1 |
Csaba, N; Fischer, S; Gander, B; Groettrup, M; Merkle, HP; Mueller, M; Schlosser, E | 1 |
Gao, C; Hu, X; Tan, H; Zhang, N; Zhou, J | 1 |
Hirashima, N; Kawashima, Y; Sakai, T; Tahara, K; Takeuchi, H; Yamamoto, H | 2 |
Cartmell, SH; El Haj, AJ; Jones, GL; Marshall, MJ; Motta, A | 1 |
Feng, Q; Liu, W; She, Z | 1 |
Gao, C; Huang, D; Tan, H; Wu, J | 1 |
Abdel-Fattah, WI; Jiang, T; Khan, Y; Laurencin, CT; Nair, LS | 1 |
Almeida, AJ; Alpar, HO; Florindo, HF; Gonçalves, LM; Pandit, S | 1 |
Delie, F; Gaumet, M; Gurny, R | 1 |
Corrigan, OI; De Sousa Menezes, F; Endter, S; Li, X; Medina, C; Radomski, A; Radomski, MW; Tajber, L | 1 |
Jiang, TY; Sun, CS; Wang, CY; Wang, SL; Wang, ZH; Wang, ZY | 1 |
Lou, T; Peng, W; Song, G; Wang, X | 1 |
Chen, F; He, C; Ikada, Y; Mo, X; Su, Y; Wang, H | 1 |
Chen, SJ; Huang, RN; Lin, CC; Tseng, CS; Tuan, WC | 1 |
Gao, HX; Li, MJ; Wang, TW; Wu, Y | 1 |
Hirashima, N; Kawashima, Y; Tahara, K; Yamamoto, H | 1 |
Liang, W; Zheng, C | 1 |
Goyal, AK; Jain, AK; Mangal, S; Mishra, N; Pawar, D; Tiwari, S; Vaidya, B; Vyas, SP | 1 |
Chung, YI; Kim, JC; Kim, K; Kim, YH; Kwon, IC; Lee, SY; Tae, G | 1 |
Bari, ML; Inatsu, Y; Juneja, V; Kawamoto, S; Kitagawa, T; Nei, D | 1 |
Chantawongvuti, R; Jaturapiree, P; Muangnapoh, C; Veerajetbodithat, J | 1 |
Dong, NG; Hu, P; Qiu, XF; Shi, JW; Su, W; Sun, ZQ | 1 |
Kawashima, Y; Li, D; Takeuchi, H; Yamamoto, H | 1 |
Bormann, KH; Carvalho, C; Gellrich, NC; Haberstroh, K; Kaps, C; Kuschnierz, J; Mülhaupt, R; Ritter, K; Sittinger, M | 1 |
Gu, H; Kotadia, NK; Li, J; Shah, BA; Wu, Z; Yuan, X | 1 |
Furukawa, S; Kawashima, Y; Tahara, K; Yamamoto, H | 1 |
Du, YZ; Hu, FQ; Wang, L; Yuan, H; Zhou, JP; Zhou, YY | 1 |
Ahmad, S; Gellert, P; Johnston, BF; Mackay, SP; Schatzlein, AG; Sengupta, D; Uchegbu, IF | 1 |
Cormack, R; Gultepe, E; Jost, E; Levy, CO; Makrigiorgos, GM; Nagesha, D; Singh, S; Sridhar, S; Tada, DB | 1 |
Dong, S; Huang, Y; Liang, W; Zheng, C; Zheng, X | 1 |
Bolden, G; Chinta, DM; Dash, S; Graves, RA; Hazari, S; Kishore, V; Mandal, TK; Pamujula, S | 1 |
Augustijns, P; Bal, S; Bouwstra, J; Broere, F; Hagenaars, N; Jiskoot, W; Kaijzel, E; Keijzer, C; Löwik, C; Mallants, R; Que, I; Slütter, B; van Eden, W | 1 |
Abulencia, JP; Chaieb, S; Fredericks, LP; Griffon, DJ; Ragetly, GR | 1 |
Ding, F; Gu, X; Hu, W; Liu, J; Tang, X; Wu, J; Yang, Y; Zhu, Q | 1 |
Anbu, J; Anilbabu, B; Nirmala, L; Ravichandran, V; Shanmugarajan, TS; Siva, L; Sivakumar, SM; Sukumaran, N; Swarnalakshmi, R | 1 |
Bouwstra, JA; Gander, B; Henriksen-Lacey, M; Jiskoot, W; Johansen, P; Kündig, TM; Mohanan, D; Perrie, Y; Slütter, B | 1 |
Chen, NL; Jin, YQ; Shen, H; Shen, ZL; Wang, YC; Zhang, PH; Zhang, ZF | 1 |
Kai, H; Madhukar, KS; Qin, L; Wang, X; Yan, Y; Zhang, R | 1 |
Choi, SW; Xia, Y; Zhang, Y | 1 |
Booysen, LI; Kalombo, L; Katata, L; Ramalapa, B; Semete, B; Swai, H; Venter, JD; Verschoor, JA | 1 |
Bando, Y; Kawashima, Y; Morishita, R; Samura, S; Tahara, K; Tsuji, K; Tsujimoto, H; Tsukada, Y; Yamamoto, H | 1 |
Ahmad, FJ; Akhter, S; Jain, GK; Jayabalan, N; Khar, RK; Pathan, SA; Talegaonkar, S | 1 |
El-Sherbiny, IM; Selvam, P; Smyth, HD | 1 |
Kuo, YC; Yeh, CF | 1 |
Blackwood, K; Huang, H; MacNeil, S; Xie, D | 1 |
Grabnar, PA; Kristl, J | 1 |
Kelly, JG; Keohane, K; Kerrigan, SW; Kirby, BP; Lyons, P; Ramtoola, Z | 1 |
Boey, F; Venkatraman, SS; Xia, Y | 1 |
Boey, F; Heng, BC; Prawirasatya, M; Venkatraman, SS; Xia, Y | 1 |
Bilensoy, E; Calis, S; Capan, Y; Cirpanli, Y; Erdogar, N; Gegu, C; Launay, M; Leturgez, T; Ozturk, K; Yerlikaya, F | 1 |
Bhattarai, N; Cooper, A; Kievit, FM; Rossol, M; Zhang, M | 1 |
Chakravarthi, SS; Robinson, DH | 1 |
Hu, Y; Jin, J; Kompella, UB; Ma, JX; Park, K; Tyagi, P; Xu, X; Zheng, Z; Zhou, KK | 1 |
Deng, Y; Fu, J; He, N; Jin, S; Wang, D; Wang, H; Wang, T; Yang, W | 1 |
Carvalho, AJ; Grande, R | 1 |
Casettari, L; Castagnino, E; Howdle, SM; Illum, L; Lewis, A; Stolnik, S | 1 |
Li, S; Xu, H; Yan, Y | 1 |
Jiang, T; Li, YL; Luo, LL; Ruan, CG; Wang, GX; Yin, TY | 1 |
Antikainen, O; Cervera, MF; de la Paz, N; Fundora, J; Hatanpää, T; Heinämäki, J; López, O; Maunu, SL; Nogueira, A; Virtanen, T; Yliruusi, J | 1 |
Han, CM; Hu, XL; Li, QY; Sun, HF; Wang, XG; You, CG; Zhang, LP; Zheng, YR | 1 |
Chang, R; Chen, Z; Li, Z | 1 |
Li, B; Li, L; Li, X; Zhao, M; Zhou, C | 1 |
Peng, M; Ren, H; Xu, Y; Zeng, C; Zeng, P | 1 |
Astete, C; Leonardi, C; Morgan, T; Murugeshu, A; Sabliov, CM | 1 |
Lipner, J; Liu, W; Sung, HW; Thomopoulos, S; Xia, Y; Xie, J; Yeh, YC | 1 |
Kim, WJ; Namgung, R; Singha, K | 1 |
Abdolghaffari, AH; Abdollahi, M; Atyabi, F; Baeeri, M; Baghaei, A; Dinarvand, R; Fazeli, MR; Jamalifar, H; Mahbod, M; Mahdaviani, P; Mohammadirad, A; Saadatzadeh, A | 1 |
Ammon-Treiber, S; Dong, M; Friedel, G; Griese, EU; Klotz, U; Lehr, CM; Loretz, B; Mürdter, TE; Nafee, N; Philippi, C; Schaefer, UF | 1 |
Chiono, V; Ciardelli, G; Gentile, P; Matsiko, A; Montevecchi, FM; Nandagiri, VK; Ramtoola, Z; Tonda-Turo, C | 1 |
Bárzana, E; David, L; Garnica-Gonzalez, M; Gimeno, M; Pacheco, N; Shirai, K; Trombotto, S | 1 |
Franco, RA; Lee, BT; Nguyen, TH | 1 |
Chen, XG; Cheng, XJ; Kong, M; Li, J; Li, JJ; Liu, WF | 1 |
Atkins, GJ; Aw, MS; Findlay, DM; Gulati, K; Losic, D; Ramakrishnan, S | 1 |
Kreuter, J; Selzer, T; Wieber, A | 1 |
Ding, F; Gu, X; Gu, Y; Hu, N; Liu, J; Liu, Y; Xue, C; Yang, Y | 1 |
Parveen, S; Sahoo, SK | 1 |
Hirashima, N; Kawashima, Y; Tadokoro, S; Tahara, K; Yamamoto, H | 1 |
Broere, F; Jiskoot, W; Keijzer, C; Slütter, B; van der Zee, R; van Eden, W | 1 |
Han, CM; Li, QY; Wang, XG; You, CG; Zhang, LP; Zheng, YR | 1 |
Ji, L; Li, F; Zhu, A | 1 |
Fang, Y; Jiang, S; Lü, J; Pan, L; Wang, G; Wang, Y; Zhang, Y; Zhang, Z; Zhou, P | 1 |
Fattal, E; Gueutin, C; Hillaireau, H; Le Droumaguet, B; Mura, S; Nicolas, J; Tsapis, N; Zanna, S | 1 |
Mahapatro, A; Singh, DK | 1 |
Chang, NJ; Issariyakul, N; Jhung, YR; Yao, CK; Yeh, ML | 1 |
El-Sherbiny, IM; Smyth, HD | 1 |
Go, DP; Gras, SL; Hung, A; O'Connor, AJ | 1 |
Cao, QR; Chen, D; Chen, L; Cui, J; Zhu, L | 1 |
Bi, Y; Cao, D; Sun, J; Sun, M; Zhang, X; Zheng, A | 1 |
Holzwarth, JM; Liu, X; Ma, PX | 1 |
Gao, C; Han, C; Hu, X; Li, Q; Ma, L; Sun, H; Wang, X; You, C; Zheng, Y | 1 |
Cho, DW; Kang, HW | 1 |
Chang, J; Han, J; Ji, W; Liao, Z; Niu, R; Wang, H; Wang, X; Wu, B; Yu, M; Zhang, F; Zhang, H; Zhao, P | 1 |
Amoozgar, Z; Lin, Q; Park, J; Yeo, Y | 1 |
Hirashima, N; Kawashima, Y; Tadokoro, S; Tahara, K | 1 |
Schwendeman, SP; Zhang, Y | 1 |
Ammon-Treiber, S; Dong, M; Lehr, CM; Loretz, B; Mürdter, TE; Philippi, C; Schaefer, UF; Schwab, M | 1 |
Cametti, C; Chronopoulou, L; Cutonilli, A; Dentini, M; Palocci, C | 1 |
Chen, XG; Cheng, XJ; Dang, QF; Kong, M; Li, J; Wei, YN; Zhou, X | 1 |
Cheow, WS; Hadinoto, K; Yang, Y | 1 |
Everaert, A; Hermans, K; Ludwig, A; Van den Plas, D; Weyenberg, W | 1 |
Baldassari, S; Cafaggi, S; Caviglioli, G; Gaglianone, N; Parodi, B; Russo, E; Schito, AM | 1 |
Kawashima, Y; Kurashima, H; Takeuchi, H; Tsujimoto, H; Yamamoto, H; Yang, M; Yokoyama, T | 1 |
Duarte, AR; Gomes, ME; Mano, JF; Popa, EG; Reis, RL; Santo, VE | 1 |
Babensee, JE; Park, J | 1 |
Chennazhi, KP; Jayakumar, R; Nair, SV; Sathish, D; Shalumon, KT; Tamura, H | 1 |
Amarnath, K; Jeevitha, D | 1 |
Kim, JS; Lee, JY; Lee, SH; Nam, YS; Oh, MH; Park, TG | 1 |
Brayden, DJ; Coco, R; Jérôme, C; Plapied, L; Pourcelle, V; Préat, V; Schneider, YJ | 1 |
Bonfield, W; Edirisinghe, M; Enayati, M; Stride, E | 1 |
Gurtler, JB; Jin, T | 1 |
Baraldi, C; Belletti, D; Forni, F; Gamberini, MC; Ruozi, B; Tosi, G; Vandelli, MA | 1 |
Chen, F; Li, Y; Nie, J; Yang, D | 1 |
Hu, Q; Jiang, Z; Li, Y; Liu, M; Wang, Z; Zhang, K; Zhao, Q; Zhuang, P | 1 |
Pack, DW; Wang, CH; Xia, Y; Xu, Q | 1 |
Lai, J; Lin, J; Lin, W; Wu, C; Xu, S | 1 |
Bai, S; Hao, J; Lai, L; Nyiawung, D; Silber, A; Yang, T | 1 |
Li, AD; Li, L; Ma, JY; Sun, ZZ; Xu, XX; Zheng, W; Zheng, YF; Zhou, HM; Zhou, M | 1 |
Cametti, C; Chronopoulou, L; Dentini, M; Devirgiliis, LC; Giardi, MF; Massimi, M; Palocci, C | 1 |
An, Y; Chen, XG; Kong, M; Li, J; Liu, Y; Ma, FK | 1 |
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Chen, G; Huang, J; Li, Z; Liu, Y; Ren, J; Wang, G; Wu, X | 1 |
Ajduković, JJ; Ignjatović, NL; Kojić, VV; Marković, SB; Penov-Gaši, KM; Uskoković, DP | 1 |
Anderski, J; Langer, K; Mahlert, L; Mulac, D | 1 |
Al-Rjoub, MF; Augsburger, JJ; Banerjee, RK; Donnell, AM; Kaval, N; Manna, S | 1 |
Ahmad, N; Ahmad, R; Alam, MA; Jalees Ahmad, F; Umar, S | 1 |
Braekmans, K; Chiesa, E; Colzani, B; Conti, B; Dorati, R; Genta, I; Modena, T; Pisani, S | 1 |
Alomrani, AH; Ashour, AE; Badran, MM; Harisa, GI; Kumar, A; Yassin, AE | 1 |
Fan, Q; Feng, N; Huang, P; Jiang, Z; Li, Z; Liang, J; Liu, J; Liu, Y; Wang, Z; Yan, F | 1 |
Biehl, A; De Rossi, C; Koch, M; Lehr, CM; Loretz, B; Murgia, X; Yasar, H | 1 |
Hinestroza, JP; Potiyaraj, P; Promphet, N; Rattanawaleedirojn, P; Rodthongkum, N; Siralertmukul, K; Soatthiyanon, N; Thanawattano, C | 1 |
Haddadi, T; Najafi, MA; Rahnama, M; Ramezani, F | 1 |
Coimbra, JSDR; de Alvarenga, ES; de Oliveira, EB; Guimarães, LM; Perim, RB; Soares, LS; Teixeira, AVNC | 1 |
Aldrian, A; Beer, B; Guebitz, GM; Herrero Acero, E; Russmayer, H; Skopek, L; Steiger, MG; Vecchiato, S | 1 |
Amini, M; Arefian, E; Atyabi, F; Dinarvand, R; Gholami, M; Mottaghitalab, F; Rastegari, A | 1 |
Atyabi, F; Azizi, G; Ghalamfarsa, G; Hassannia, H; Hojjat-Farsangi, M; Jadidi-Niaragh, F; Masjedi, A; Mirshafiey, A; Namdar, A; Nikkhoo, A; Rastegari, A; Soleimanpour, H | 1 |
Ahmadi, A; Atyabi, F; Ghalamfarsa, G; Ghani, S; Hassannia, H; Heydarzadeh Asl, S; Hojjat-Farsangi, M; Irandoust, M; Jadidi-Niaragh, F; Karoon Kiani, F; Malakotikhah, F; Masjedi, A; Nabi Afjadi, M; Namdar, A | 1 |
He, J; Hu, X; Li, Q; Liao, Y; Lu, J; Xiao, J; Xiong, C; Yong, X | 1 |
Abbasvali, M; Bonyadian, M; Dini, H; Fallah, AA; Soleimani, M | 1 |
Hyun, H; Jo, G; Jung, JS; Lee, S; Yang, DH | 1 |
Ahmadi, A; Boroumand-Noughabi, S; Hassannia, H; Heydari, M; Hojjat-Farsangi, M; Izadi, S; Jadidi-Niaragh, F; Karoon Kiani, F; Keramati, MR; Masjedi, A; Mohammadi, H; Sadat Eshaghi, F; Salimifard, S; Shahdadnejad, K | 1 |
Hou, W; Li, Y; Lu, W; Ren, J; Wang, B; Wang, H | 1 |
De Schryver, M; Delputte, PL; Elbrink, K; Kiekens, F; Van Hees, S | 1 |
Gregory, H; Phillips, JB | 1 |
Ahmad, MW; Ahmad, MY; Cha, H; Chae, KS; Chang, Y; Ghazanfari, A; Ho, SL; Lee, GH; Liu, S; Marasini, S; Tegafaw, T; Yue, H | 1 |
Akbaba, S; Atila, D; Keskin, D; Tezcaner, A; Tezcaner, T | 1 |
Antoniewska, A; Cazón, P; Rutkowska, J; Vázquez, M | 1 |
Liu, J; Shi, Q; Tao, H; Xie, X; Yao, J; Zhi, H | 1 |
Chen, YZ; Li, MY; Li, WY; Liu, RJ; Wang, BN; Yang, L | 1 |
Al-Nemrawi, NK; Altawabeyeh, RM; Darweesh, RS | 1 |
Abbaszadeh-Goudarzi, K; Ahmadi, M; Ansari Dezfouli, E; Chalajour, H; Ebrahimi, F; Gholizadeh Navashenaq, J; Hashemi, V; Hassannia, H; Hojjat-Farsangi, M; Izadi, S; Jadidi-Niaragh, F; Karoon Kiani, F; Karpisheh, V; Mahmoud Salehi Khesht, A; Mohammadi, M; Mortazavi Bulus, M; Nasr Esfahani, M; Shahmohammadi Farid, S; Soleimani, A | 1 |
Alassaif, ER; Alassaif, FR; Dhanapal, J; Kaushik, AK | 1 |
Bahador, A; Keshavarz Valian, N; Pourhajibagher, M | 1 |
Asal, HA; El-Hagrasy, MA; Shoueir, KR; Toson, EA | 1 |
Gao, C; Gao, Y; Liu, Y; Ma, Y; Wu, Y | 1 |
Alves, GDSG; Araujo, HC; Dos Santos Oliveira, M; Monteiro, DR; Morato, DN; Pessan, JP; Ramírez Carmona, W; Sato, C | 1 |
Han, Z; Jia, L; Li, N; Liu, Y; Liu, Z; Ma, H; Nwafor, EO; Pan, H; Pan, W; Pang, X; Tian, B; Zhao, Z; Zhu, S | 1 |
Galeeva, AI; Galyametdinov, YG; Selivanova, NM | 1 |
Han, C; Pan, X; Wang, X; Wu, P; You, C | 1 |
Karaś, M; Kazimierczak, W; Kordowska-Wiater, M; Kowalczyk, D; Skrzypek, T | 1 |
Li, D; Li, H; Li, W; Wang, K; Yu, Y | 1 |
Li, Y; Lin, W; Liu, Z; Lv, Z; Pan, Y; Ren, X; Wang, H; Wang, W; Yao, Q; Yu, H; Yuan, H; Zuo, Y | 1 |
Barati Naeeni, N; Ghafaripour, H; Homayouni Tabrizi, M; Karimi, E | 1 |
Chakim, Z; Foroglou, N; Kapoukranidou, D; Karagkiozaki, V; Logothetidis, S; Poulios, C; Zarampoukas, T | 1 |
Agturk, G; Cakmak, HY; Cakmak, Z; Ege, H; Ege, ZR; Enguven, G; Gunduz, O; Sarmis, A; Yilmaz, S; Yontem, FD | 1 |
Chen, G; He, K; Li, H; Luo, P; Wen, L; Xia, L; Xiao, W; Xie, S; Yu, C; Zhang, M; Zhang, Z; Zhou, Z | 1 |
Augustin, E; Banach-Kopeć, A; Kulesza, J; Mania, S; Staszczyk, K; Tylingo, R | 1 |
Antonsen, S; Aprilia, WR; Cuong, NC; Eijsink, VGH; Jitprasertwong, P; Khamphio, M; Lorentzen, SB; Luesukprasert, K; Maneedaeng, A; Min, TT; Soem, CN; Teeranitayatarn, K; Tuveng, TR; Yamabhai, M | 1 |
13 review(s) available for lactic acid and chitosan
Article | Year |
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Mucoadhesive nanoparticulate systems for peptide drug delivery.
Topics: Animals; Biocompatible Materials; Chitin; Chitosan; Colloids; Drug Carriers; Gastric Mucosa; Guinea Pigs; Intestinal Absorption; Lactic Acid; Liposomes; Male; Nebulizers and Vaporizers; Peptides; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rats | 2001 |
Development of oral microencapsulated forms for delivering viral vaccines.
Topics: Adjuvants, Immunologic; Administration, Oral; Animals; Capsules; Chitin; Chitosan; Drug Compounding; Humans; Immunity, Mucosal; Lactic Acid; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Viral Vaccines | 2002 |
Nanoparticle-mediated gene delivery: state of the art.
Topics: Animals; Chitosan; DNA, Recombinant; Drug Administration Routes; Endocytosis; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Humans; Lactic Acid; Lipids; Mice; Mice, Inbred BALB C; Nanostructures; Organ Specificity; Polyethyleneimine; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polylysine; Polymers; Silicon Dioxide; Transfection | 2004 |
[Development of gene delivery system using PLGA nanospheres].
Topics: Cells, Cultured; Chitosan; Diffusion; Emulsions; Gene Transfer Techniques; Genetic Vectors; Humans; Lactic Acid; Nanoparticles; Nanospheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Solvents | 2007 |
Polymers in small-interfering RNA delivery.
Topics: Cellulose; Chitosan; Cyclodextrins; Dendrimers; Gene Silencing; Gene Transfer Techniques; Genetic Vectors; Humans; Lactic Acid; Nanoparticles; Nanotubes, Carbon; Peptides; Polyethyleneimine; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; RNA, Small Interfering; Transfection | 2011 |
Biodegradable nanoparticles are excellent vehicle for site directed in-vivo delivery of drugs and vaccines.
Topics: Chitosan; Cyanoacrylates; Gelatin; Humans; Lactic Acid; Nanocapsules; Neoplasms; Particle Size; Pharmaceutical Vehicles; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Vaccines | 2011 |
Functionalized synthetic biodegradable polymer scaffolds for tissue engineering.
Topics: Apatites; Biomarkers; Biomimetic Materials; Carboxylic Acids; Cells, Cultured; Chitosan; Extracellular Matrix; Gelatin; Gene Expression; Humans; Lactic Acid; Microscopy, Electron, Scanning; Phosphates; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Surface Properties; Tissue Engineering | 2012 |
Overview of the preparation of organic polymeric nanoparticles for drug delivery based on gelatine, chitosan, poly(d,l-lactide-co-glycolic acid) and polyalkylcyanoacrylate.
Topics: Animals; Chitosan; Cyanoacrylates; Drug Delivery Systems; Gelatin; Lactic Acid; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers | 2014 |
Biomaterial scaffolds used for the regeneration of spinal cord injury (SCI).
Topics: Alginates; Animals; Apoptosis; Axons; Biocompatible Materials; Chitosan; Collagen; Disease Models, Animal; Drug Delivery Systems; Fibrin; Humans; Hyaluronic Acid; Inflammation; Lactic Acid; Materials Testing; Peptides; Polyesters; Polymers; Sepharose; Spinal Cord; Spinal Cord Injuries; Spinal Cord Regeneration; Stem Cells; Tissue Engineering; Tissue Scaffolds | 2014 |
Microencapsulation of protein drugs for drug delivery: strategy, preparation, and applications.
Topics: Animals; Biocompatible Materials; Capsules; Chitosan; Drug Carriers; Drug Compounding; Equipment Design; Humans; Lactic Acid; Microspheres; Particle Size; Peptides; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Protein Stability; Recombinant Proteins; Surface Properties | 2014 |
Polymer-based nanoparticles for oral insulin delivery: Revisited approaches.
Topics: Administration, Oral; Alginates; Chitosan; Dextrans; Drug Carriers; Drug Delivery Systems; Humans; Hyaluronic Acid; Insulin; Lactic Acid; Nanoparticles; Polyamines; Polyesters; Polyglutamic Acid; Polymers | 2015 |
Fabrication and Handling of 3D Scaffolds Based on Polymers and Decellularized Tissues.
Topics: Bone and Bones; Cartilage, Articular; Cell Culture Techniques; Cell Survival; Cells, Immobilized; Chitosan; Extracellular Matrix; Fibrin Tissue Adhesive; Humans; Imaging, Three-Dimensional; Lactic Acid; Microscopy, Confocal; Polyglycolic Acid; Polyhydroxyethyl Methacrylate; Polylactic Acid-Polyglycolic Acid Copolymer; Stem Cells; Tissue Engineering; Tissue Scaffolds | 2017 |
Materials for peripheral nerve repair constructs: Natural proteins or synthetic polymers?
Topics: Animals; Biocompatible Materials; Chitosan; Collagen; Humans; Lactic Acid; Nerve Regeneration; Peripheral Nerve Injuries; Peripheral Nerves; Polyesters; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Tissue Scaffolds | 2021 |
4 trial(s) available for lactic acid and chitosan
Article | Year |
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Chitosan delivery systems for the treatment of oral mucositis: in vitro and in vivo studies.
Topics: Adult; Animals; Antifungal Agents; Biological Availability; Body Weight; Chitosan; Cricetinae; Cross-Over Studies; Drug Delivery Systems; Drug Therapy, Combination; Fluorouracil; Gels; Histocytochemistry; Humans; Lactic Acid; Male; Mesocricetus; Mouth Mucosa; Nystatin; Polyphosphates; Saliva; Stomatitis; Survival Rate; Treatment Outcome; Water | 2004 |
Alginate-chitosan-PLGA composite microspheres induce both innate and adaptive immune response through parenteral immunization in fish.
Topics: Adaptive Immunity; Aeromonas hydrophila; Alginates; Animals; Antibodies, Bacterial; Chitosan; Cyprinidae; Fish Diseases; Glucuronic Acid; Gram-Negative Bacterial Infections; Hexuronic Acids; Immunity, Innate; Lactic Acid; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Voltage-Dependent Anion Channels | 2013 |
PEG-functionalized microparticles selectively target inflamed mucosa in inflammatory bowel disease.
Topics: Administration, Oral; Adult; Case-Control Studies; Chitosan; Colitis, Ulcerative; Crohn Disease; Drug Carriers; Drug Delivery Systems; Female; Humans; Intestinal Mucosa; Lactic Acid; Male; Microspheres; Nanoparticles; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2013 |
A Novel Method for Preparing Surface-Modified Fluocinolone Acetonide Loaded PLGA Nanoparticles for Ocular Use: In Vitro and In Vivo Evaluations.
Topics: Administration, Ophthalmic; Animals; Chitosan; Cross-Over Studies; Delayed-Action Preparations; Drug Carriers; Eye; Fluocinolone Acetonide; Lactic Acid; Male; Nanoparticles; Particle Size; Poloxamer; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rabbits | 2016 |
506 other study(ies) available for lactic acid and chitosan
Article | Year |
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In vitro effects of brain derived neurotrophic factor released from microspheres.
Topics: Animals; Biocompatible Materials; Brain-Derived Neurotrophic Factor; Cell Survival; Cells, Cultured; Chick Embryo; Chitin; Chitosan; Drug Compounding; Ganglia, Spinal; Kinetics; Lactic Acid; Mesencephalon; Nerve Tissue Proteins; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Retina | 1994 |
[An experimental study of prevention of peridural adhesion following laminectomy].
Topics: Animals; Chitin; Chitosan; Dura Mater; Female; Gelatin Sponge, Absorbable; Lactic Acid; Laminectomy; Male; Polyesters; Polymers; Rabbits; Random Allocation; Tissue Adhesions | 1998 |
Effects of various adjuvants (lactic acid, glycerol, and chitosan) on the injectability of a calcium phosphate cement.
Topics: Adjuvants, Pharmaceutic; Bone Cements; Bone Substitutes; Calcium Phosphates; Chitin; Chitosan; Compressive Strength; Glycerol; Injections; Lactic Acid; Materials Testing; Microscopy, Electron, Scanning; Spectrophotometry, Infrared; Stress, Mechanical; X-Ray Diffraction | 1999 |
Antimicrobial films produced from chitosan.
Topics: Acetic Acid; Anti-Infective Agents; Chitin; Chitosan; Chlorides; Citric Acid; Food Preservatives; Formates; Hydrogen-Ion Concentration; Ions; Lactic Acid; Osmolar Concentration; Polymers; Solutions; Temperature; Viscosity | 1999 |
Mucoadhesive DL-lactide/glycolide copolymer nanospheres coated with chitosan to improve oral delivery of elcatonin.
Topics: Acrylic Resins; Administration, Oral; Alginates; Animals; Biocompatible Materials; Calcitonin; Calcium; Chelating Agents; Chitin; Chitosan; Delayed-Action Preparations; Digestive System Physiological Phenomena; Drug Delivery Systems; Fluorescein-5-isothiocyanate; Glucuronic Acid; Hexuronic Acids; In Vitro Techniques; Intubation; Lactic Acid; Male; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rats; Rats, Wistar; Tablets, Enteric-Coated; Time Factors | 2000 |
Studies on gynaecological hydrophilic lactic acid preparations. Part 3: Effects of chitosan on the properties of methylcellulose gels.
Topics: Adhesiveness; Administration, Intravaginal; Chitin; Chitosan; Gels; Hydrogen-Ion Concentration; Lactic Acid; Methylcellulose; Ointments; Pharmaceutic Aids; Viscosity | 2000 |
Low molecular weight chitosan prevents the progression of low dose streptozotocin-induced slowly progressive diabetes mellitus in mice.
Topics: Administration, Oral; Animals; Blood Glucose; Chitin; Chitosan; Diabetes Mellitus, Experimental; Disease Progression; Dose-Response Relationship, Drug; Glucosamine; Lactic Acid; Male; Mice; Mice, Inbred ICR; Molecular Weight; Substance Withdrawal Syndrome | 2000 |
Cell release from alginate immobilized Lactococcus lactis ssp. lactis in chitosan and alginate coated beads.
Topics: Alginates; Animals; Cattle; Chitin; Chitosan; Female; Fermentation; Food Handling; Glucuronic Acid; Hexuronic Acids; Hydrogen-Ion Concentration; Kinetics; Lactic Acid; Lactococcus lactis; Microspheres; Milk | 2001 |
Design of biodegradable particles for protein delivery.
Topics: Animals; Biodegradation, Environmental; Chitin; Chitosan; Drug Delivery Systems; Drug Design; Lactic Acid; Male; Mice; Mice, Inbred BALB C; Polyesters; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Proteins | 2002 |
[Application of 2% clindamycin cream in the treatment of bacterial vaginosis and valuation of methylcellulose gel containing the complex of Chitosan F and PVP k-90 with lactic acid as carrier for intravaginally adhbited medicines in the cases of pregnanci
Topics: Administration, Intravaginal; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Chitin; Chitosan; Clindamycin; Female; Gels; Humans; Lactic Acid; Methylcellulose; Obstetric Labor, Premature; Ointments; Pharmaceutic Aids; Povidone; Pregnancy; Pregnancy Complications, Infectious; Treatment Outcome; Vaginosis, Bacterial | 2001 |
Rat osteoblast functions on the o-carboxymethyl chitosan-modified poly(D,L-lactic acid) surface.
Topics: Alkaline Phosphatase; Animals; Cell Adhesion; Cell Differentiation; Cell Division; Chitin; Chitosan; Coated Materials, Biocompatible; Lactic Acid; Materials Testing; Osteoblasts; Polyesters; Polymers; Rats; Spectrum Analysis; Surface Properties | 2001 |
Modulation of osteoblast function using poly(D,L-lactic acid) surfaces modified with alkylation derivative of chitosan.
Topics: Alkaline Phosphatase; Animals; Animals, Newborn; Biocompatible Materials; Cell Division; Cell Survival; Cells, Cultured; Chitin; Chitosan; Coloring Agents; Kinetics; Lactic Acid; Membranes, Artificial; Microscopy, Electron, Scanning; Osteoblasts; Oxygen; Polyesters; Polymers; Rats; Skull; Tetrazolium Salts; Thiazoles; Time Factors; Water | 2002 |
Covalent immobilization of chitosan/heparin complex with a photosensitive hetero-bifunctional crosslinking reagent on PLA surface.
Topics: Animals; Azides; Biocompatible Materials; Cell Adhesion; Cells, Cultured; Chitin; Chitosan; Cross-Linking Reagents; Dose-Response Relationship, Drug; Electrolytes; Fibroblasts; Heparin; Lactic Acid; Mice; Models, Chemical; Platelet Activation; Polyesters; Polymers; Spectroscopy, Fourier Transform Infrared; Ultraviolet Rays | 2002 |
Immobilization of natural macromolecules on poly-L-lactic acid membrane surface in order to improve its cytocompatibility.
Topics: Animals; Cell Adhesion; Cell Division; Cells, Cultured; Chitin; Chitosan; Chondrocytes; Coated Materials, Biocompatible; Collagen; Gelatin; In Vitro Techniques; Lactic Acid; Macromolecular Substances; Materials Testing; Microscopy, Electron, Scanning; Polyesters; Polymers; Polymethyl Methacrylate; Rabbits; Surface Properties; Tetrazolium Salts; Thiazoles | 2002 |
Periodontal delivery of ipriflavone: new chitosan/PLGA film delivery system for a lipophilic drug.
Topics: Chitin; Chitosan; Drug Delivery Systems; Isoflavones; Lactic Acid; Lipids; Periodontal Pocket; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Solubility | 2003 |
Stimulation of gamma-aminobutyric acid synthesis activity in brown rice by a chitosan/glutamic acid germination solution and calcium/calmodulin.
Topics: Calcium; Calmodulin; Chitin; Chitosan; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Germination; Glutamate Decarboxylase; Glutamic Acid; Lactic Acid; Seeds; Water | 2003 |
Biomimetic surface modification of poly(L-lactic acid) with chitosan and its effects on articular chondrocytes in vitro.
Topics: Animals; Biocompatible Materials; Bromodeoxyuridine; Cartilage, Articular; Cattle; Cell Adhesion; Cell Division; Cell Survival; Chitin; Chitosan; Chondrocytes; Collagen; Coloring Agents; DNA; Enzyme-Linked Immunosorbent Assay; Glycosaminoglycans; In Vitro Techniques; Lactic Acid; Microscopy, Electron, Scanning; Nitrogen; Polyesters; Polymers; Surface Properties; Tetrazolium Salts; Thiazoles; Time Factors; Water | 2003 |
Pancreatic islet culture and transplantation using chitosan and PLGA scaffolds.
Topics: Animals; Chitin; Chitosan; Islets of Langerhans; Islets of Langerhans Transplantation; Lactic Acid; Male; Organ Culture Techniques; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rats; Rats, Wistar | 2003 |
[Enhancement of gastrointestinal absorption of chitosan-coated insulin-loaded poly (lactic-co-glycolic acid) nanoparticles].
Topics: Animals; Blood Glucose; Chitin; Chitosan; Diabetes Mellitus, Experimental; Drug Carriers; Drug Delivery Systems; Hypoglycemic Agents; Insulin; Intestinal Absorption; Lactic Acid; Male; Nanotechnology; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Random Allocation; Rats; Rats, Wistar | 2003 |
[Preparation and biological evaluation of PLA/chitosan composite materials].
Topics: Animals; Biocompatible Materials; Cell Adhesion; Cells, Cultured; Chitin; Chitosan; Female; Guinea Pigs; Lactic Acid; Male; Materials Testing; Polyesters; Polymers; Rabbits | 2003 |
Preparation of porous scaffolds by using freeze-extraction and freeze-gelation methods.
Topics: Alginates; Animals; Biocompatible Materials; Cell Adhesion; Cell Culture Techniques; Cell Division; Cell Line; Chitin; Chitosan; Crystallization; Freezing; Gels; Glucuronic Acid; Hexuronic Acids; Lactic Acid; Osteoblasts; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Porosity; Rats; Surface Properties; Tissue Engineering | 2004 |
Covalent immobilization of chitosan and heparin on PLGA surface.
Topics: Animals; Biocompatible Materials; Cell Adhesion; Cell Division; Cells, Cultured; Chitin; Chitosan; Heparin; Hepatocytes; Lactic Acid; Male; Platelet Adhesiveness; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rats; Surface Properties | 2003 |
Immobilization of chitosan onto poly-L-lactic acid film surface by plasma graft polymerization to control the morphology of fibroblast and liver cells.
Topics: Adsorption; Animals; Cell Differentiation; Cell Line; Cell Size; Chitin; Chitosan; Coated Materials, Biocompatible; Crystallization; Fibroblasts; Hepatocytes; Hot Temperature; Humans; Lactic Acid; Materials Testing; Mice; Molecular Conformation; Polyesters; Polymers; Surface Properties; Tissue Engineering | 2004 |
Polymers for induction of revascularization in the rat fascial flap: application of vascular endothelial growth factor and pancreatic islet cells.
Topics: Animals; Cell Line; Chitin; Chitosan; Fascia; Humans; Hypoxia; Immunohistochemistry; Insulin; Islets of Langerhans Transplantation; Lactic Acid; Microspheres; Neovascularization, Physiologic; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rats; Recombinant Proteins; Tissue Engineering; Vascular Endothelial Growth Factor A | 2003 |
Synthesis and characterization of a brush-like copolymer of polylactide grafted onto chitosan.
Topics: Biocompatible Materials; Calorimetry, Differential Scanning; Chitin; Chitosan; Lactic Acid; Magnetic Resonance Spectroscopy; Polyesters; Polymers; Scattering, Radiation; Spectroscopy, Fourier Transform Infrared; Temperature; Transition Temperature; X-Rays | 2004 |
Incorporation of a high concentration of mineral or vitamin into chitosan-based films.
Topics: Calcium Gluconate; Chemical Phenomena; Chemistry, Physical; Chitin; Chitosan; Food Packaging; Food, Fortified; Lactic Acid; Mechanics; Minerals; Permeability; Rheology; Thermodynamics; Vitamin E | 2004 |
Microencapsulation of hydrophilic drug substances using biodegradable polyesters. Part II: Implants allowing controlled drug release--a feasibility study using bisphosphonates.
Topics: Adjuvants, Pharmaceutic; Anti-Inflammatory Agents; Biocompatible Materials; Biodegradation, Environmental; Chitin; Chitosan; Diphosphonates; Drug Compounding; Drug Implants; Feasibility Studies; Lactic Acid; Microscopy, Electron, Scanning; Microspheres; Pamidronate; Polyesters; Polyglycolic Acid; Sucrose; Surface Properties | 2004 |
A protein delivery system: biodegradable alginate-chitosan-poly(lactic-co-glycolic acid) composite microspheres.
Topics: Alginates; Body Fluids; Chitin; Chitosan; Contraceptive Agents; Diffusion; Glucuronic Acid; Hexuronic Acids; Lactic Acid; Materials Testing; Microspheres; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Proteins; Serum Albumin, Bovine | 2004 |
[A comparative study on two different absorbable intramedullary nails in treating metacarpal and phalanx fractures].
Topics: Adolescent; Adult; Bone Nails; Chitosan; Female; Follow-Up Studies; Fracture Fixation, Intramedullary; Fracture Healing; Fractures, Bone; Humans; Lactic Acid; Male; Metacarpus; Polyesters; Polymers | 2004 |
Surface-modified PLGA nanosphere with chitosan improved pulmonary delivery of calcitonin by mucoadhesion and opening of the intercellular tight junctions.
Topics: Absorption; Adhesiveness; Administration, Inhalation; Aerosols; Animals; Calcitonin; Chemical Phenomena; Chemistry, Physical; Chitosan; Drug Delivery Systems; Emulsions; Guinea Pigs; Lactic Acid; Lung; Male; Microspheres; Molecular Weight; Mucous Membrane; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Surface Properties; Tight Junctions | 2005 |
Microencapsulation peptide and protein drugs delivery system.
Topics: Alginates; Capsules; Chitosan; Drug Carriers; Drug Delivery Systems; Glucuronic Acid; Hexuronic Acids; Lactic Acid; Peptides; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Proteins; Zinc | 2005 |
Responses of cultured macrophages to microspheres.
Topics: Animals; Cell Line; Cells, Cultured; Chitosan; Drug Delivery Systems; Lactic Acid; Lipopolysaccharides; Macrophages; Mice; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Tumor Necrosis Factor-alpha | 2005 |
Effects of alginate coated on PLGA microspheres for delivery tetracycline hydrochloride to periodontal pockets.
Topics: Alginates; Anti-Bacterial Agents; Biocompatible Materials; Chitosan; Drug Carriers; Drug Compounding; Glucuronic Acid; Hexuronic Acids; Humans; Lactic Acid; Microscopy, Electron, Scanning; Microspheres; Particle Size; Periodontal Pocket; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Surface Properties; Tetracycline | 2004 |
Porous poly (DL-lactic acid) modified chitosan-gelatin scaffolds for tissue engineering.
Topics: Absorption; Biocompatible Materials; Cell Adhesion; Cell Culture Techniques; Cell Movement; Cell Proliferation; Cells, Cultured; Chitosan; Elasticity; Fibroblasts; Gelatin; Humans; Lactic Acid; Materials Testing; Polyesters; Polymers; Tensile Strength; Tissue Engineering; Water | 2005 |
Development of a single dose tetanus toxoid formulation based on polymeric microspheres: a comparative study of poly(D,L-lactic-co-glycolic acid) versus chitosan microspheres.
Topics: Animals; Chemistry, Pharmaceutical; Chitosan; Dose-Response Relationship, Drug; Drug Administration Schedule; Guinea Pigs; Lactic Acid; Male; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Tetanus Toxoid | 2005 |
[Clinical study of phalange fractures treated by absorbable intramedullary nail in replantation of severed finger].
Topics: Absorbable Implants; Adolescent; Adult; Bone Nails; Chitosan; Female; Finger Injuries; Finger Phalanges; Follow-Up Studies; Fracture Fixation, Intramedullary; Humans; Lactic Acid; Male; Polymers; Replantation; Treatment Outcome; Young Adult | 2005 |
Cell viability of chitosan-containing semi-interpenetrated hydrogels based on PCL-PEG-PCL diacrylate macromer.
Topics: Acrylates; Animals; Biocompatible Materials; Cell Proliferation; Cell Survival; Cells, Cultured; Chitosan; Coloring Agents; Drug Delivery Systems; Fibroblasts; Hot Temperature; Hydrogel, Polyethylene Glycol Dimethacrylate; Hydrogels; Lactic Acid; Light; Mice; NIH 3T3 Cells; Nitrogen; Polyesters; Polyethylene Glycols; Polyglycolic Acid; Polymers; Polystyrenes; Spectrometry, X-Ray Emission; Spectroscopy, Fourier Transform Infrared; Temperature; Tetrazolium Salts; Thiazoles; Time Factors; Ultraviolet Rays; Water | 2005 |
[Preparation of alginate-chitosan-poly (lactic-co-glycolic acid) composite microsphere and its regulation of protein release].
Topics: Alginates; Chitosan; Drug Delivery Systems; Lactic Acid; Microspheres; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Serum Albumin, Bovine | 2005 |
Manufacture of porous polymer nerve conduits through a lyophilizing and wire-heating process.
Topics: Absorbable Implants; Axons; Biocompatible Materials; Chitosan; Chromium; Freeze Drying; Guided Tissue Regeneration; Hot Temperature; Inflammation; Lactic Acid; Microscopy, Electron, Scanning; Nerve Regeneration; Nerve Tissue; Nickel; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Prostheses and Implants; Tissue Engineering | 2005 |
The sustaining effect of three polymers on the release of chlorhexidine from a controlled release drug device for root canal disinfection.
Topics: Analysis of Variance; Anti-Infective Agents, Local; Chitosan; Chlorhexidine; Coated Materials, Biocompatible; Delayed-Action Preparations; Lactic Acid; Materials Testing; Microscopy, Electron, Scanning; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Polymethyl Methacrylate; Porosity; Root Canal Irrigants; Spectrophotometry, Ultraviolet; Surface Properties | 2005 |
Application of tissue engineering techniques for rotator cuff regeneration using a chitosan-based hyaluronan hybrid fiber scaffold.
Topics: Animals; Biocompatible Materials; Cells, Cultured; Chitosan; Collagen Type I; Feasibility Studies; Female; Fibroblasts; Hyaluronic Acid; Lactic Acid; Polyesters; Polymers; Rabbits; Regeneration; Rotator Cuff; Tensile Strength; Tissue Engineering | 2005 |
Use of chitosan to prolong mozzarella cheese shelf life.
Topics: Anti-Infective Agents; Cheese; Chitosan; Colony Count, Microbial; Enterobacteriaceae; Food Preservatives; Lactic Acid; Lactobacillus; Solutions; Time Factors | 2005 |
[Effects of astragalus polysaccharides-chitosan/polylactic acid composite material on biological behavior of canine bone marrow stromal cells cultured in vitro].
Topics: Animals; Astragalus propinquus; Bone Marrow Cells; Cell Proliferation; Cells, Cultured; Chitosan; Collagen Type I; Dogs; Drugs, Chinese Herbal; Extracellular Matrix; Female; Lactic Acid; Male; Osteocalcin; Polyesters; Polymers; Polysaccharides; Stromal Cells; Tissue Engineering | 2005 |
Spatially controlled co-culture of neurons and glial cells.
Topics: Animals; Biocompatible Materials; Cell Line, Tumor; Chitosan; Coculture Techniques; Humans; Lactic Acid; Neuroglia; Neurons; PC12 Cells; Polyesters; Polyethylene Glycols; Polyethyleneimine; Polymers; Polymethacrylic Acids; Rats | 2005 |
Incorporation of protein-eluting microspheres into biodegradable nerve guidance channels for controlled release.
Topics: Algorithms; Chitin; Chitosan; Delayed-Action Preparations; Drug Compounding; Drug Delivery Systems; Epidermal Growth Factor; Lactic Acid; Microspheres; Nerve Regeneration; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Proteins; Recombinant Proteins; Serum Albumin, Bovine | 2006 |
One-step preparation of polyelectrolyte-coated PLGA microparticles and their functionalization with model ligands.
Topics: Biocompatible Materials; Biodegradation, Environmental; Biotin; Chemistry, Pharmaceutical; Chitosan; Electrolytes; Fluorescamine; Lactic Acid; Ligands; Microscopy, Confocal; Microscopy, Electron, Scanning; Molecular Weight; Nanostructures; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Spectrometry, X-Ray Emission; Static Electricity; Technology, Pharmaceutical | 2006 |
Strong systemic and mucosal immune responses to surface-modified PLGA microspheres containing recombinant hepatitis B antigen administered intranasally.
Topics: Administration, Intranasal; Animals; Chitosan; Delayed-Action Preparations; Drug Carriers; Drug Stability; Female; Hepatitis B Antibodies; Hepatitis B Surface Antigens; Hepatitis B Vaccines; Immunity, Mucosal; Immunoglobulin A, Secretory; In Vitro Techniques; Interferon-gamma; Interleukin-2; Lactic Acid; Mice; Mice, Inbred BALB C; Microscopy, Electron, Scanning; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Surface Properties | 2006 |
Biodegradable and complexed microspheres used for sustained delivery and activity protection of SOD.
Topics: Alginates; Biocompatible Materials; Biodegradation, Environmental; Chitosan; Drug Delivery Systems; Glucuronic Acid; Hexuronic Acids; Lactic Acid; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Superoxide Dismutase | 2006 |
Formulation and in vitro evaluation of bisphosphonate loaded microspheres for implantation in osteolysis.
Topics: Alendronate; Bone Density Conservation Agents; Chemistry, Pharmaceutical; Chitosan; Drug Implants; Emulsions; Lactic Acid; Microspheres; Osteolysis; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Solubility; Solvents; Surface Properties | 2006 |
Preparation and characterization of novel hybrid of chitosan-g-lactic acid and montmorillonite.
Topics: Bentonite; Biocompatible Materials; Carbohydrate Conformation; Carbohydrate Sequence; Chitosan; Lactic Acid; Magnetic Resonance Spectroscopy; Nanostructures; Silicon; Sodium; Spectroscopy, Fourier Transform Infrared; Thermodynamics; X-Ray Diffraction | 2006 |
A blank slate? Layer-by-layer deposition of hyaluronic acid and chitosan onto various surfaces.
Topics: 3T3 Cells; Animals; Cell Nucleus; Chitosan; Cross-Linking Reagents; Crystallization; Cytoskeleton; Hyaluronic Acid; Indicators and Reagents; Kinetics; Lactic Acid; Mice; Microscopy, Fluorescence; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Quartz; Surface Properties | 2006 |
In vitro evaluation of chitosan/poly(lactic acid-glycolic acid) sintered microsphere scaffolds for bone tissue engineering.
Topics: 3T3 Cells; Alkaline Phosphatase; Animals; Biocompatible Materials; Chitosan; Lactic Acid; Mice; Microscopy, Electron, Scanning; Microspheres; Osteoblasts; Osteocalcin; Osteopontin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Reproducibility of Results; Sialoglycoproteins; Tissue Engineering | 2006 |
Protective immunity in rats by intranasal immunization with Streptococcus mutans glucan-binding protein D encapsulated into chitosan-coated poly(lactic-co-glycolic acid) microspheres.
Topics: Administration, Intranasal; Animals; Carrier Proteins; Chitosan; Enzyme-Linked Immunosorbent Assay; Kinetics; Lactic Acid; Lectins; Male; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rats; Rats, Sprague-Dawley; Saliva; Streptococcus mutans; Surface Properties | 2006 |
Stable cationic microparticles for enhanced model antigen delivery to dendritic cells.
Topics: Antigens; Antigens, CD; CD83 Antigen; Cells, Cultured; Cetrimonium; Cetrimonium Compounds; Chitosan; DEAE-Dextran; Dendritic Cells; Drug Delivery Systems; Excipients; Humans; Immunoglobulins; Lactic Acid; Membrane Glycoproteins; Particle Size; Phagocytosis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Surface Properties | 2006 |
Characterization of emulsified chitosan-PLGA matrices formed using controlled-rate freezing and lyophilization technique.
Topics: Biocompatible Materials; Cell Culture Techniques; Chitosan; Dimyristoylphosphatidylcholine; Drug Delivery Systems; Freeze Drying; Freezing; Green Fluorescent Proteins; Lactic Acid; Models, Statistical; Muramidase; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Porosity; Solvents; Temperature; Tissue Engineering | 2006 |
[Preparation and release behavior of chitosan scaffolds encapsulating proteins loaded in PLGA microspheres].
Topics: Chitosan; Drug Carriers; Freeze Drying; Lactic Acid; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Serum Albumin, Bovine; Tissue Engineering | 2006 |
[Effects of astragalus polysaccharides-chitosan/polylactic acid scaffolds and bone marrow stem cells on repairing supra-alveolar periodontal defects in dogs].
Topics: Alveolar Bone Loss; Animals; Astragalus propinquus; Bone Marrow Cells; Bone Regeneration; Chitosan; Dogs; Drugs, Chinese Herbal; Lactic Acid; Osteogenesis; Polyesters; Polymers; Stem Cells; Tissue Engineering | 2006 |
Studies on gynaecological hydrophilic lactic acid preparations, Part 7: use of chitosan as lactic acid carrier in intravaginal tablets (globuli vaginales).
Topics: Adhesives; Administration, Intravaginal; Chemistry, Pharmaceutical; Chitosan; Drug Carriers; Gelatin; Gels; Hydrogen-Ion Concentration; Lactic Acid; Methylcellulose; Pharmaceutic Aids; Tablets; Temperature; Viscosity | 2006 |
Preparation and characterization of poly(L-lactic acid)-chitosan hybrid scaffolds with drug release capability.
Topics: Biocompatible Materials; Biomechanical Phenomena; Chitosan; Humans; Infusion Pumps, Implantable; Ketoprofen; Lactic Acid; Materials Testing; Microscopy, Electron, Scanning; Polyesters; Polymers; Tissue Engineering; Water | 2007 |
Chitosan lactate as a nonviral gene delivery vector in COS-1 cells.
Topics: Animals; Cell Survival; Chitosan; Chlorocebus aethiops; COS Cells; DNA; Gene Transfer Techniques; Genetic Vectors; Lactic Acid; Polyethyleneimine; Transfection | 2006 |
Fabrication and characterization of PLLA-chitosan hybrid scaffolds with improved cell compatibility.
Topics: Animals; Biocompatible Materials; Bone Substitutes; Cell Adhesion; Cell Culture Techniques; Cell Proliferation; Cells, Cultured; Chitosan; Lactic Acid; Materials Testing; Osteoblasts; Polyesters; Polymers; Porosity; Rats; Rats, Sprague-Dawley | 2007 |
[Acute, hemorrhagic, overgrowing vaginal inflammation caused by Streptococcus agalacitae--case study].
Topics: Acute Disease; Administration, Intravaginal; Anti-Bacterial Agents; Chitosan; Female; Humans; Inflammation; Lactic Acid; Middle Aged; Streptococcal Infections; Streptococcus agalactiae; Treatment Outcome; Vaginal Discharge; Vaginosis, Bacterial | 2006 |
Biodegradable in situ gelling system for subcutaneous administration of ellagic acid and ellagic acid loaded nanoparticles: evaluation of their antioxidant potential against cyclosporine induced nephrotoxicity in rats.
Topics: Animals; Antioxidants; Biological Availability; Chitosan; Cyclosporine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Ellagic Acid; Ethanolamines; Gels; Glycerol; Immunosuppressive Agents; Kidney; Kinetics; Lactic Acid; Male; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Propylene Glycol; Rats; Rats, Sprague-Dawley; Solvents; Temperature; Water | 2007 |
Degradation of electrospun PLGA-chitosan/PVA membranes and their cytocompatibility in vitro.
Topics: Biocompatible Materials; Cell Adhesion; Cell Proliferation; Cells, Cultured; Chitosan; Fibroblasts; Humans; Lactic Acid; Materials Testing; Membranes, Artificial; Microscopy, Electron, Scanning; Nanostructures; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Polyvinyl Alcohol; Surface Properties | 2007 |
Chitosan gels for the vaginal delivery of lactic acid: relevance of formulation parameters to mucoadhesion and release mechanisms.
Topics: Adhesiveness; Administration, Intravaginal; Animals; Chitosan; Drug Carriers; Drug Compounding; Drug Stability; Elasticity; Female; In Vitro Techniques; Lactic Acid; Materials Testing; Mucous Membrane; Swine; Tensile Strength; Vagina; Vaginal Creams, Foams, and Jellies; Viscosity | 2006 |
Surface modification and characterization of chitosan or PLGA membrane with laminin by chemical and oxygen plasma treatment for neural regeneration.
Topics: Animals; Biocompatible Materials; Cell Adhesion; Cell Proliferation; Cells, Cultured; Chitosan; Female; Lactic Acid; Laminin; Materials Testing; Nerve Regeneration; Oxygen; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rats; Rats, Wistar; Schwann Cells; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Surface Properties; Tissue Engineering; X-Rays | 2007 |
Glycol chitosan as a stabilizer for protein encapsulated into poly(lactide-co-glycolide) microparticle.
Topics: Animals; Chitosan; Foreign-Body Reaction; Lactic Acid; Male; Materials Testing; Microspheres; Muramidase; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Proteins; Rats; Rats, Sprague-Dawley; Solubility | 2007 |
Highly sensitive lactate biosensor by engineering chitosan/PVI-Os/CNT/LOD network nanocomposite.
Topics: Biosensing Techniques; Chitosan; Electrochemistry; Imidazoles; Lactic Acid; Microscopy, Electron, Scanning; Mixed Function Oxygenases; Nanocomposites; Nanotubes, Carbon; Polyvinyls; Sensitivity and Specificity | 2007 |
In vitro biocompatibility of schwann cells on surfaces of biocompatible polymeric electrospun fibrous and solution-cast film scaffolds.
Topics: Animals; Biocompatible Materials; Cell Culture Techniques; Cell Line, Tumor; Chitosan; Hydroxybutyrates; Lactic Acid; Materials Testing; Polyesters; Polymers; Prohibitins; Rats; Schwann Cells; Solutions; Surface Properties | 2007 |
Preparation, characterization and transfection efficiency of cationic PEGylated PLA nanoparticles as gene delivery systems.
Topics: Animals; Cations; Cell Line; Cell Line, Tumor; Cell Survival; Chitosan; Chlorocebus aethiops; Coated Materials, Biocompatible; COS Cells; DNA; Dose-Response Relationship, Drug; Gastric Mucosa; Gene Transfer Techniques; Genes, Reporter; Green Fluorescent Proteins; Hepatocytes; Humans; Intestinal Absorption; Lactic Acid; Luciferases; Mice; Mice, Inbred BALB C; Nanoparticles; Particle Size; Plasmids; Polyesters; Polyethylene Glycols; Polymers; Transfection | 2007 |
Preparation and characterization of cationic chitosan-modified poly(D,L-lactide-co-glycolide) copolymer nanospheres as DNA carriers.
Topics: Biocompatible Materials; Cations; Chitosan; Diffusion; DNA; Drug Compounding; Lactic Acid; Materials Testing; Nanospheres; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Porosity | 2008 |
Fabrication and characterization of PLGA/HAp composite scaffolds for delivery of BMP-2 plasmid DNA.
Topics: Biocompatible Materials; Bone Marrow Cells; Bone Morphogenetic Protein 2; Bone Morphogenetic Proteins; Bone Regeneration; Cell Adhesion; Cell Survival; Cells, Cultured; Chitosan; DNA; Durapatite; Humans; Lactic Acid; Nanostructures; Nucleic Acid Conformation; Plasmids; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Solubility; Stem Cells; Surface Properties; Time Factors; Tissue Engineering; Transfection; Transforming Growth Factor beta | 2007 |
Histological study of surface modified three dimensional poly (D, L-lactic acid) scaffolds with chitosan in vivo.
Topics: Absorbable Implants; Animals; Bone Regeneration; Chitosan; Lactic Acid; Materials Testing; Osseointegration; Osteocalcin; Polyesters; Polymers; Rabbits; Surface Properties; Time Factors; Tissue Scaffolds | 2007 |
Fabrication and evaluation of microgrooved polymers as peripheral nerve conduits.
Topics: Actins; Animals; Animals, Newborn; Biocompatible Materials; Biodegradation, Environmental; Brain-Derived Neurotrophic Factor; Cell Adhesion; Cell Culture Techniques; Cells, Cultured; Chitosan; Cytoskeleton; Dimethylpolysiloxanes; Feasibility Studies; Fluorescent Antibody Technique, Indirect; Gene Expression; Glioma; Lactic Acid; Male; Nerve Growth Factor; Peripheral Nerves; Polyesters; Polymers; Rats; Rats, Sprague-Dawley; S100 Proteins; Schwann Cells; Sciatic Nerve; Silicon; Time Factors; Vinculin | 2007 |
Hybrid nanofibrous membranes of PLGA/chitosan fabricated via an electrospinning array.
Topics: Biocompatible Materials; Cells, Cultured; Chitosan; Embryo, Mammalian; Fibroblasts; Humans; Lactic Acid; Materials Testing; Membranes, Artificial; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Skin; Tissue Engineering; Tissue Scaffolds | 2007 |
Surface modification of poly(L-lactic acid) by entrapment of chitosan and its derivatives to promote osteoblasts-like compatibility.
Topics: Alkaline Phosphatase; Animals; Cell Adhesion; Cell Cycle; Cell Proliferation; Cells, Cultured; Chitosan; Lactic Acid; Osteoblasts; Polyesters; Polymers; Rats; Rats, Sprague-Dawley; Surface Properties | 2007 |
Homogeneous chitosan-PLGA composite fibrous scaffolds for tissue regeneration.
Topics: Animals; Biocompatible Materials; Calorimetry, Differential Scanning; Cattle; Cell Proliferation; Cells, Cultured; Chitosan; Chondrocytes; Collagen Type II; Gene Expression Regulation; Lactic Acid; Microscopy, Electron, Scanning; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Temperature; Tissue Engineering; Water | 2008 |
Build up of multilayered thin films with chitosan/DNA pairs on poly(D,L-lactic acid) films: physical chemistry and sustained release behavior.
Topics: Chemical Phenomena; Chemistry, Physical; Chitosan; Delayed-Action Preparations; DNA; Drug Compounding; Drug Delivery Systems; Lactic Acid; Microscopy, Atomic Force; Muramidase; Polyesters; Polymers; Spectrometry, X-Ray Emission; Spectroscopy, Fourier Transform Infrared; Surface Properties | 2008 |
Enhancement of immune response of HBsAg loaded poly (L-lactic acid) microspheres against hepatitis B through incorporation of alum and chitosan.
Topics: Aluminum Hydroxide; Animals; Capsules; Cells, Cultured; Chitosan; Cytokines; Drug Carriers; Hepatitis B; Hepatitis B Surface Antigens; Immunoglobulin G; Lactic Acid; Membrane Potentials; Mice; Microscopy, Electron, Scanning; Microspheres; Polyesters; Polymers; Solubility; Spleen | 2007 |
Controlling the in vitro release profiles for a system of haloperidol-loaded PLGA nanoparticles.
Topics: Chitosan; Gelatin; Haloperidol; Hydrophobic and Hydrophilic Interactions; Lactic Acid; Models, Chemical; Nanoparticles; Particle Size; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Surface Properties | 2008 |
Chitosan-coated PLGA nanoparticles for DNA/RNA delivery: effect of the formulation parameters on complexation and transfection of antisense oligonucleotides.
Topics: Cell Line, Tumor; Chitosan; Coated Materials, Biocompatible; Crystallization; DNA; Drug Carriers; Drug Compounding; Humans; Lactic Acid; Lung Neoplasms; Materials Testing; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; RNA, Antisense; Transfection | 2007 |
[An experimental study on effect of astragalus polysaccharides on chitosan/polylactic acid scaffolds for repairing alveolar bone defects in dogs].
Topics: Alveolar Bone Loss; Animals; Astragalus propinquus; Biocompatible Materials; Bone Marrow Cells; Cell Proliferation; Cells, Cultured; Chitosan; Dogs; Drugs, Chinese Herbal; Guided Tissue Regeneration, Periodontal; Lactic Acid; Male; Polyesters; Polymers; Stromal Cells; Tissue Engineering; Tissue Scaffolds | 2007 |
Chitosan and lactic acid-grafted chitosan nanoparticles as carriers for prolonged drug delivery.
Topics: Chitosan; Delayed-Action Preparations; Diffusion; Drug Carriers; Lactic Acid; Materials Testing; Nanoparticles; Particle Size; Pharmaceutical Preparations; Serum Albumin, Bovine | 2006 |
Preparation of rapamycin-loaded chitosan/PLA nanoparticles for immunosuppression in corneal transplantation.
Topics: Administration, Topical; Animals; Chemistry, Pharmaceutical; Chitosan; Cholesterol; Corneal Transplantation; Drug Carriers; Electrochemistry; Immunosuppressive Agents; Isotope Labeling; Lactic Acid; Microscopy, Electron, Scanning; Nanoparticles; Ophthalmic Solutions; Polyesters; Polymers; Rabbits; Radionuclide Imaging; Radiopharmaceuticals; Sirolimus; Solubility; Technetium Tc 99m Pentetate | 2008 |
Accelerating thrombolysis with chitosan-coated plasminogen activators encapsulated in poly-(lactide-co-glycolide) (PLGA) nanoparticles.
Topics: Animals; Blood Coagulation; Cattle; Chitosan; Fibrinolytic Agents; Humans; Lactic Acid; Microscopy, Electron, Transmission; Nanoparticles; Plasminogen Activators; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers | 2008 |
Different effects of PLGA and chitosan scaffolds on human cartilage tissue engineering.
Topics: Animals; Biocompatible Materials; Chitosan; Chondrocytes; Chondrogenesis; Collagen Type II; Ear Cartilage; Humans; Lactic Acid; Male; Mice; Mice, Nude; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Tissue Engineering; Tissue Scaffolds | 2007 |
PLGA, chitosan or chitosan-coated PLGA microparticles for alveolar delivery? A comparative study of particle stability during nebulization.
Topics: Adhesiveness; Administration, Inhalation; Antibiotics, Antitubercular; Cell Line; Chemical Phenomena; Chemistry, Physical; Chitosan; Diffusion; Drug Compounding; Drug Delivery Systems; Drug Stability; Electrochemistry; Emulsions; Humans; Lactic Acid; Microscopy, Electron, Scanning; Microspheres; Molecular Weight; Mucins; Mucous Membrane; Nebulizers and Vaporizers; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Pulmonary Alveoli; Rifampin; Solvents; Tetrazolium Salts; Thiazoles | 2008 |
Establishing chitosan coated PLGA nanosphere platform loaded with wide variety of nucleic acid by complexation with cationic compound for gene delivery.
Topics: Chitosan; Delayed-Action Preparations; Diffusion; DNA; Emulsions; Fatty Acids, Monounsaturated; Gene Transfer Techniques; Lactic Acid; Nanospheres; Oligonucleotides, Antisense; Plasmids; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Quaternary Ammonium Compounds; RNA, Small Interfering; Solubility; Solvents | 2008 |
Engineering tissue tubes using novel multilayered scaffolds in the rat peritoneal cavity.
Topics: Animals; Chitosan; Coated Materials, Biocompatible; Collagen; Collagen Type I; Collagen Type III; Drug Combinations; Elastin; Implants, Experimental; Lactic Acid; Laminin; Materials Testing; Microscopy, Electron, Scanning; Peritoneal Cavity; Polyesters; Polymers; Proteoglycans; Rats; Rats, Wistar; Surface Properties; Tissue Engineering; Tissue Scaffolds | 2008 |
Investigation of particle-functionalized tissue engineering scaffolds using X-ray tomographic microscopy.
Topics: Absorptiometry, Photon; Biocompatible Materials; Chitosan; Cluster Analysis; Lactic Acid; Materials Testing; Microscopy, Electron, Scanning; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Surface Properties; Tissue Engineering; Tissue Scaffolds | 2008 |
Multilayer composite scaffolds with mechanical properties similar to small intestinal submucosa.
Topics: Animals; Cell Adhesion; Cells, Cultured; Chitosan; Diffusion; Intestinal Mucosa; Intestine, Small; Lactic Acid; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Microscopy, Electron, Scanning; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Porosity; Stress, Mechanical; Tensile Strength; Urea | 2009 |
Fibrous poly(chitosan-g-DL-lactic acid) scaffolds prepared via electro-wet-spinning.
Topics: Animals; Cell Proliferation; Chitosan; Fibroblasts; Lactic Acid; Male; Materials Testing; Microscopy, Electron, Scanning; Polyesters; Porosity; Rabbits; Spectrophotometry, Infrared; Tensile Strength; Tissue Scaffolds; Wettability | 2008 |
Rheological, microstructural, and in vitro characterization of hybrid chitosan-polylactic acid/hydroxyapatite composites.
Topics: Biocompatible Materials; Body Fluids; Chitosan; Cross-Linking Reagents; Durapatite; Elasticity; Iridoid Glycosides; Iridoids; Lactic Acid; Materials Testing; Microscopy, Electron, Scanning; Polyesters; Polymers; Porosity; Rheology; Surface Properties; Tissue Scaffolds; Viscosity | 2009 |
Preparation and biological properties of PLLA/beta-TCP composites reinforced by chitosan fibers.
Topics: Body Fluids; Bone Substitutes; Calcium Phosphates; Chitosan; Compressive Strength; Elasticity; Lactic Acid; Materials Testing; Polyesters; Polymers; Porosity; Stress, Mechanical; Surface Properties; Tensile Strength | 2008 |
Effects of a chitosan membrane coated with polylactic and polyglycolic acid on bone regeneration in a rat calvarial defect.
Topics: Animals; Bone Regeneration; Bone Substitutes; Chitosan; Coated Materials, Biocompatible; Lactic Acid; Male; Materials Testing; Membranes, Artificial; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rats; Rats, Sprague-Dawley; Skull; Skull Fractures; Treatment Outcome | 2007 |
PLGA microparticle-embedded thermosensitive hydrogels for sustained release of hydrophobic drugs.
Topics: Capsules; Chitosan; Delayed-Action Preparations; Diffusion; Hot Temperature; Hydrophobic and Hydrophilic Interactions; Lactic Acid; Materials Testing; Particle Size; Pharmaceutical Preparations; Poloxamer; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2007 |
Effect of different biomedical membranes on alkali-burned cornea.
Topics: Animals; Burns, Chemical; Chitosan; Collagen; Corneal Diseases; Disease Models, Animal; Epithelium, Corneal; Eye Burns; Lactic Acid; Membranes, Artificial; Polyesters; Polymers; Rabbits; Sodium Hydroxide; Wound Healing | 2008 |
Effect of preparative variables on small interfering RNA loaded Poly(D,L-lactide-co-glycolide)-chitosan submicron particles prepared by emulsification diffusion method.
Topics: Chitosan; Diffusion; Drug Carriers; Emulsions; Freeze Drying; Lactic Acid; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; RNA, Small Interfering | 2008 |
Preparation, characterization, and mucoadhesive properties of chitosan-coated microspheres encapsulated with cyclosporine A.
Topics: Adhesiveness; Cell Proliferation; Chemistry, Pharmaceutical; Chitosan; Chromatography, High Pressure Liquid; Cyclosporine; Drug Carriers; Drug Compounding; Humans; Immunosuppressive Agents; In Vitro Techniques; Lactic Acid; Microscopy, Electron, Scanning; Microspheres; Mucins; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solubility; Surface Properties; T-Lymphocytes | 2008 |
Co-encapsulation of an antigen and CpG oligonucleotides into PLGA microparticles by TROMS technology.
Topics: Adjuvants, Immunologic; Animals; Antibodies; Antibody Formation; Antigens; Cells, Cultured; Chemistry, Pharmaceutical; Chitosan; Dendritic Cells; Drug Carriers; Female; Immunity, Cellular; Injections, Intradermal; Interferon-gamma; Interleukin-4; Lactic Acid; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Oligodeoxyribonucleotides; Ovalbumin; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solubility; Technology, Pharmaceutical; Th1 Cells; Time Factors; Vaccines | 2008 |
PLGA/chitosan composites from a combination of spray drying and supercritical fluid foaming techniques: new carriers for DNA delivery.
Topics: Buffers; Cell Adhesion; Cell Survival; Cells, Cultured; Chitosan; Desiccation; DNA; Drug Carriers; Escherichia coli; Fibroblasts; Gene Transfer Techniques; Humans; Hydrogen-Ion Concentration; Lactic Acid; Luciferases; Microscopy, Electron, Scanning; Molecular Weight; Phosphates; Plasmids; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Porosity; Powders; Sodium Chloride; Time Factors; Tissue Engineering; Transfection; X-Ray Diffraction | 2008 |
Biocompatible and biodegradable ultrafine fibrillar scaffold materials for tissue engineering by facile grafting of L-lactide onto chitosan.
Topics: Biocompatible Materials; Cell Line; Cell Survival; Chitosan; Drug Delivery Systems; Fibroblasts; Humans; Lactic Acid; Tissue Engineering | 2008 |
Understanding the adsorption mechanism of chitosan onto poly(lactide-co-glycolide) particles.
Topics: Adsorption; Chitosan; Drug Delivery Systems; Lactic Acid; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Static Electricity | 2008 |
Formulation, characterization and evaluation of rotavirus encapsulated PLA and PLGA particles for oral vaccination.
Topics: Administration, Oral; Animals; Cattle; Chemistry, Pharmaceutical; Chitosan; Circular Dichroism; Drug Compounding; Lactic Acid; Particle Size; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rotavirus; Serum Albumin, Bovine; Vaccination; Vaccines | 2009 |
Chitosan/poly(L-lactic acid) multilayered membrane for guided tissue regeneration.
Topics: Animals; Biocompatible Materials; Cell Adhesion; Chitosan; Drug Carriers; Epithelial Cells; Guided Tissue Regeneration; Lactic Acid; Membranes, Artificial; Osteoblasts; Osteogenesis; Polyesters; Polymers; Rats | 2009 |
In vitro and in vivo evaluation of a biodegradable chitosan-PLA composite peripheral nerve guide conduit material.
Topics: Absorbable Implants; Animals; Biocompatible Materials; Chitosan; Elasticity; Lactic Acid; Male; Nerve Regeneration; Polyesters; Polymers; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Tensile Strength | 2008 |
The study of improved controlled release of vincristine sulfate from collagen-chitosan complex film.
Topics: Absorbable Implants; Analysis of Variance; Antineoplastic Agents, Phytogenic; Calorimetry, Differential Scanning; Chitosan; Collagen; Collagenases; Drug Implants; Emulsions; Lactic Acid; Microscopy, Electron, Scanning; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Porosity; Surface Properties; Tensile Strength; Time Factors; Vincristine | 2008 |
Lung-specific delivery of paclitaxel by chitosan-modified PLGA nanoparticles via transient formation of microaggregates.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; Chitosan; Coumarins; Lactic Acid; Lung; Lung Neoplasms; Male; Mice; Nanoparticles; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Surface Properties; Thiazoles | 2009 |
RhBMP-2 microspheres-loaded chitosan/collagen scaffold enhanced osseointegration: an experiment in dog.
Topics: Animals; Biocompatible Materials; Bone Morphogenetic Protein 2; Chitosan; Collagen; Dental Implantation, Endosseous; Dogs; Humans; Lactic Acid; Male; Materials Testing; Microscopy, Electron, Scanning; Microspheres; Osseointegration; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Recombinant Proteins; Tissue Scaffolds | 2009 |
Multinozzle low-temperature deposition system for construction of gradient tissue engineering scaffolds.
Topics: Biocompatible Materials; Chitosan; Collagen; Equipment Design; Freeze Drying; Gelatin; Lactic Acid; Materials Testing; Microscopy, Electron, Scanning; Models, Theoretical; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Surface Properties; Temperature; Tissue Engineering; Tissue Scaffolds | 2009 |
The influence of chitosan content in cationic chitosan/PLGA nanoparticles on the delivery efficiency of antisense 2'-O-methyl-RNA directed against telomerase in lung cancer cells.
Topics: Base Sequence; Cations; Cell Line, Tumor; Chitosan; Chromatography, Gel; Chromatography, High Pressure Liquid; DNA Primers; Humans; Lactic Acid; Lung Neoplasms; Microscopy, Confocal; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymerase Chain Reaction; RNA, Antisense; Telomerase | 2009 |
Chitosan ascorbate: a chitosan salt with improved penetration enhancement properties.
Topics: Absorption; Adhesiveness; Adjuvants, Pharmaceutic; Animals; Ascorbic Acid; Caco-2 Cells; Cell Survival; Chitosan; Dextrans; Elasticity; Electric Impedance; Fluorescein-5-isothiocyanate; Humans; Lactic Acid; Mouth Mucosa; Swine; Tight Junctions; Viscosity | 2008 |
Gelatin/chitosan/hyaluronan scaffold integrated with PLGA microspheres for cartilage tissue engineering.
Topics: Animals; Biocompatible Materials; Cartilage; Cell Proliferation; Chitosan; Chondrocytes; Compressive Strength; Gelatin; Hyaluronic Acid; Lactic Acid; Microspheres; Models, Biological; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Porosity; Rabbits; Tissue Engineering | 2009 |
The intracellular uptake ability of chitosan-coated Poly (D,L-lactide-co-glycolide) nanoparticles.
Topics: Adhesives; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Chitosan; Delayed-Action Preparations; Electrochemistry; Excipients; Humans; Lactic Acid; Microscopy, Electron, Scanning; Nanoparticles; Paclitaxel; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2008 |
Cell proliferation and controlled drug release studies of nanohybrids based on chitosan-g-lactic acid and montmorillonite.
Topics: Bentonite; Biocompatible Materials; Cell Proliferation; Chitosan; Drug Delivery Systems; HL-60 Cells; Humans; Ibuprofen; Lactic Acid; Nanostructures; Nanotechnology; Stress, Mechanical; Tensile Strength; Tissue Engineering; X-Ray Diffraction | 2009 |
Release of rifampicin from chitosan, PLGA and chitosan-coated PLGA microparticles.
Topics: Chitosan; Drug Carriers; Drug Delivery Systems; Drug Stability; Kinetics; Lactic Acid; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rifampin | 2008 |
Electrospun non-woven nanofibrous hybrid mats based on chitosan and PLA for wound-dressing applications.
Topics: Bacterial Adhesion; Bandages; Biocompatible Materials; Chitosan; Electrochemical Techniques; Escherichia coli; Lactic Acid; Materials Testing; Molecular Structure; Nanostructures; Polyesters; Polymers; Staphylococcus aureus; Surface Properties; Wound Healing | 2009 |
Collagen-chitosan polymer as a scaffold for the proliferation of human adipose tissue-derived stem cells.
Topics: Absorbable Implants; Adipose Tissue; Antigens, CD; Biocompatible Materials; Cell Differentiation; Cell Proliferation; Cells, Cultured; Chitosan; Collagen; Cross-Linking Reagents; Glucose; Humans; Lactic Acid; Materials Testing; Microscopy, Electron, Scanning; Stem Cells; Tissue Scaffolds | 2009 |
The stress relaxation characteristics of composite matrices etched to produce nanoscale surface features.
Topics: Biocompatible Materials; Biomechanical Phenomena; Chitosan; Lactic Acid; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Stress, Mechanical | 2009 |
The t-PA-encapsulated PLGA nanoparticles shelled with CS or CS-GRGD alter both permeation through and dissolving patterns of blood clots compared with t-PA solution: an in vitro thrombolysis study.
Topics: Animals; Blood Coagulation; Cattle; Chitosan; Drug Delivery Systems; Humans; In Vitro Techniques; Lactic Acid; Nanoparticles; Nanotechnology; Oligopeptides; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Recombinant Proteins; Spectroscopy, Fourier Transform Infrared; Thrombolytic Therapy; Tissue Plasminogen Activator | 2009 |
Porous nano-HA/collagen/PLLA scaffold containing chitosan microspheres for controlled delivery of synthetic peptide derived from BMP-2.
Topics: Alkaline Phosphatase; Animals; Bone Morphogenetic Protein 2; Cells, Cultured; Chitosan; Collagen; Compressive Strength; Delayed-Action Preparations; Durapatite; Hydrolysis; Lactic Acid; Mesenchymal Stem Cells; Microspheres; Polyesters; Polymers; Porosity; Rabbits; Tissue Engineering; Tissue Scaffolds | 2009 |
Enhanced electrostatic interaction between chitosan-modified PLGA nanoparticle and tumor.
Topics: Animals; Cell Line, Tumor; Cell Survival; Chitosan; Coumarins; Drug Carriers; Humans; Hydrogen-Ion Concentration; Lactic Acid; Lung; Lung Neoplasms; Male; Mice; Mice, Inbred Strains; Microscopy, Confocal; Nanoparticles; Neoplasm Transplantation; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Static Electricity; Thiazoles; Xenograft Model Antitumor Assays | 2009 |
Composite fibrous membranes of PLGA and chitosan prepared by coelectrospinning and coaxial electrospinning.
Topics: Biocompatible Materials; Buffers; Cell Adhesion; Cell Proliferation; Cell Survival; Chitosan; Electrochemistry; Fibroblasts; Humans; Lactic Acid; Membranes, Artificial; Microscopy, Electron, Scanning; Phosphates; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solutions; Tensile Strength; Water | 2010 |
Photo-initiated grafting of gelatin/N-maleic acyl-chitosan to enhance endothelial cell adhesion, proliferation and function on PLA surface.
Topics: Adsorption; Biomimetic Materials; Cell Adhesion; Cell Proliferation; Cell Survival; Cells, Cultured; Chitosan; Endothelial Cells; Gelatin; Humans; Lactic Acid; Light; Materials Testing; Photochemistry; Polyesters; Polymers; Tissue Engineering | 2009 |
Preparation and characterization of homogeneous chitosan-polylactic acid/hydroxyapatite nanocomposite for bone tissue engineering and evaluation of its mechanical properties.
Topics: Bone Substitutes; Chitosan; Compressive Strength; Crystallization; Durapatite; Elastic Modulus; Lactic Acid; Materials Testing; Nanostructures; Particle Size; Polyesters; Polymers; Porosity; Surface Properties; Tissue Engineering | 2009 |
Incorporation of a sequential BMP-2/BMP-7 delivery system into chitosan-based scaffolds for bone tissue engineering.
Topics: Animals; Biocompatible Materials; Bone Morphogenetic Protein 2; Bone Morphogenetic Protein 7; Cell Proliferation; Cell Survival; Cells, Cultured; Chitosan; Lactic Acid; Male; Mesenchymal Stem Cells; Microscopy, Electron, Scanning; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Tissue Engineering; X-Ray Microtomography | 2009 |
Effect of Lactobacillus plantarum and chitosan in the reduction of browning of pericarp Rambutan (Nephelium lappaceum).
Topics: Biofilms; Chitosan; Colony Count, Microbial; Desiccation; Food Preservation; Food Preservatives; Fruit; Humidity; Lactic Acid; Lactobacillus plantarum; Maillard Reaction; Sapindaceae; Temperature | 2009 |
Composite microspheres induce the sustained release and the control of the initial release of water soluble drugs.
Topics: Alginates; Capsules; Cefazolin; Chitosan; Delayed-Action Preparations; Excipients; Lactic Acid; Microscopy, Electron, Scanning; Microspheres; Particle Size; Pharmaceutical Preparations; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solubility; Water | 2009 |
Relevance of the colloidal stability of chitosan/PLGA nanoparticles on their cytotoxicity profile.
Topics: Adenosine Triphosphate; Animals; Cell Line; Cell Survival; Chitosan; Colloids; Culture Media; Dose-Response Relationship, Drug; Drug Carriers; Drug Stability; Electric Impedance; Electrochemical Techniques; Glycolates; Humans; Hydrogen-Ion Concentration; Lactic Acid; Materials Testing; Microscopy, Atomic Force; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Serum; Surface Properties | 2009 |
Fabrication and characterization of chitosan coated braided PLLA wire using aligned electrospun fibers.
Topics: Animals; Biocompatible Materials; Chitosan; Electronics; Equipment Design; Erythrocytes; Hemolysis; Hemostasis; Humans; Hydrogen-Ion Concentration; Kinetics; Lactic Acid; Materials Testing; Mice; Microscopy, Electron, Scanning; Platelet Adhesiveness; Polyesters; Polymers; Regeneration; Stress, Mechanical; Tensile Strength; Time Factors; Water; Wound Healing; X-Rays | 2009 |
Composite hydrogel formulations of stratifin to control MMP-1 expression in dermal fibroblasts.
Topics: 14-3-3 Proteins; Biomarkers, Tumor; Chitosan; Exonucleases; Exoribonucleases; Fibroblasts; Humans; Hydrogels; Lactic Acid; Matrix Metalloproteinase 1; Neoplasm Proteins; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Recombinant Proteins; Skin | 2009 |
Sustained delivery of salbutamol and beclometasone from spray-dried double emulsions.
Topics: Adrenergic beta-Agonists; Albuterol; Anti-Asthmatic Agents; Beclomethasone; Chitosan; Delayed-Action Preparations; Emulsions; Lactic Acid; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solubility | 2010 |
Surface modification of mitoxantrone-loaded PLGA nanospheres with chitosan.
Topics: Chitosan; Drug Delivery Systems; Elements; Glycolates; Lactic Acid; Mitoxantrone; Nanospheres; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Surface Properties | 2009 |
Degradation properties of the electrostatic assembly PDLLA/CS/CHS nerve conduit.
Topics: Animals; Chitosan; Lactic Acid; Peripheral Nerves; Prostheses and Implants; Rats; Rats, Sprague-Dawley; Regeneration | 2009 |
Concomitant delivery of a CTL-restricted peptide antigen and CpG ODN by PLGA microparticles induces cellular immune response.
Topics: Animals; Capsules; Chitosan; Female; Interferon-gamma; Lactic Acid; Ligands; Mice; Mice, Inbred C57BL; Oligodeoxyribonucleotides; Ovalbumin; Peptide Fragments; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Protamines; T-Lymphocytes, Cytotoxic; Toll-Like Receptors | 2009 |
Preparation and properties of an injectable scaffold of poly(lactic-co-glycolic acid) microparticles/chitosan hydrogel.
Topics: Animals; Biocompatible Materials; Cell Adhesion; Cell Proliferation; Cells, Cultured; Chitosan; Chondrocytes; Hydrogel, Polyethylene Glycol Dimethacrylate; Injections; Lactic Acid; Materials Testing; Microspheres; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rabbits; Tissue Engineering | 2008 |
Improved cellular uptake of chitosan-modified PLGA nanospheres by A549 cells.
Topics: Adenocarcinoma; Biological Transport, Active; Cell Line, Tumor; Cell Survival; Chemistry, Pharmaceutical; Chitosan; Clathrin; Coated Pits, Cell-Membrane; Dose-Response Relationship, Drug; Drug Carriers; Endocytosis; Humans; Hypertonic Solutions; Kinetics; Lactic Acid; Lung Neoplasms; Microscopy, Confocal; Nanospheres; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Spectrometry, Fluorescence; Surface Properties; Technology, Pharmaceutical; Temperature | 2009 |
Osteoblast: osteoclast co-cultures on silk fibroin, chitosan and PLLA films.
Topics: Animals; Biocompatible Materials; Chitosan; Coculture Techniques; Fibroins; Lactic Acid; Materials Testing; Mice; Osteoblasts; Osteoclasts; Polyesters; Polymers; Tissue Engineering | 2009 |
Self-assembly model, hepatocytes attachment and inflammatory response for silk fibroin/chitosan scaffolds.
Topics: Animals; Chitosan; Female; Fibroins; Hepatocytes; Lactic Acid; Polyesters; Polymers; Porosity; Rats; Rats, Sprague-Dawley; Silk; Tensile Strength; Tissue Engineering | 2009 |
The design of biodegradable microcarriers for induced cell aggregation.
Topics: Amines; Animals; Biocompatible Materials; Cell Aggregation; Cell Count; Cell Proliferation; Cell Shape; Cell Survival; Chitosan; Chondrocytes; Hydrolysis; Lactic Acid; Lactose; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Microspheres; Polyesters; Polymers; Rabbits; Surface Properties; Time Factors | 2010 |
Functionalization of chitosan/poly(lactic acid-glycolic acid) sintered microsphere scaffolds via surface heparinization for bone tissue engineering.
Topics: Adsorption; Alkaline Phosphatase; Animals; Bone and Bones; Cell Proliferation; Cell Survival; Chitosan; Compressive Strength; Heparin; Immobilized Proteins; Lactic Acid; Mice; Microscopy, Electron, Scanning; Microspheres; Osteoblasts; Osteocalcin; Photoelectron Spectroscopy; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Porosity; Solubility; Surface Properties; Tissue Engineering; Tissue Scaffolds | 2010 |
Surface modified polymeric nanoparticles for immunisation against equine strangles.
Topics: Adsorption; Alginates; Animals; Bacterial Proteins; Buffers; Cell Wall; Chitosan; Delayed-Action Preparations; Glucuronic Acid; Hexuronic Acids; Horses; Lactic Acid; Magnetic Resonance Spectroscopy; Nanoparticles; Particle Size; Polyesters; Polymers; Polyvinyl Alcohol; Respiratory Tract Infections; Solvents; Static Electricity; Streptococcal Infections; Streptococcal Vaccines; Streptococcus equi | 2010 |
Interaction of biodegradable nanoparticles with intestinal cells: the effect of surface hydrophilicity.
Topics: Biocompatible Materials; Caco-2 Cells; Carbocyanines; Cell Survival; Chitosan; Fluorescent Dyes; Humans; Intestinal Mucosa; Intracellular Space; Lactic Acid; Microscopy, Confocal; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Static Electricity; Surface Properties | 2010 |
Platelet compatibility of PLGA, chitosan and PLGA-chitosan nanoparticles.
Topics: Blood Platelets; Chitosan; Collagen; Drug Carriers; Flow Cytometry; Humans; Integrin beta3; Lactic Acid; Magnetic Resonance Spectroscopy; Microscopy, Electron, Scanning; Nanoparticles; Nanotechnology; P-Selectin; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Platelet-Rich Plasma; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers | 2009 |
Trimethylated chitosan-conjugated PLGA nanoparticles for the delivery of drugs to the brain.
Topics: Animals; Brain; Chitosan; Drug Carriers; Lactic Acid; Metabolic Clearance Rate; Methylation; Mice; Mice, Transgenic; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Tissue Distribution | 2010 |
Fabrication of nano-fibrous PLLA scaffold reinforced with chitosan fibers.
Topics: Chitosan; Lactic Acid; Materials Testing; Microscopy, Electron, Scanning; Nanotechnology; Polyesters; Polymers; Porosity; Tissue Engineering; Tissue Scaffolds | 2009 |
Biocompatibility, alignment degree and mechanical properties of an electrospun chitosan-P(LLA-CL) fibrous scaffold.
Topics: Biocompatible Materials; Caproates; Chitosan; Lactic Acid; Lactones; Materials Testing; Polymers; Tissue Engineering; Tissue Scaffolds | 2009 |
Effect of recombinant galectin-1 on the growth of immortal rat chondrocyte on chitosan-coated PLGA scaffold.
Topics: Animals; Cartilage; Cell Adhesion; Cell Aggregation; Cell Movement; Chitosan; Chondrocytes; Galectin 1; Lactic Acid; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Recombinant Proteins; Thiogalactosides; Tissue Engineering; Tissue Scaffolds; Water | 2010 |
[Preparation and drug release property of paclitaxel nanoparticles].
Topics: Antineoplastic Agents, Phytogenic; Chitosan; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Drug Delivery Systems; Lactic Acid; Nanoparticles; Paclitaxel; Particle Size; Polyesters; Polymers | 2009 |
Chitosan-modified poly(D,L-lactide-co-glycolide) nanospheres for improving siRNA delivery and gene-silencing effects.
Topics: Cell Culture Techniques; Cell Line, Tumor; Chitosan; Drug Carriers; Drug Compounding; Gene Silencing; Humans; Lactic Acid; Luciferases, Firefly; Microscopy, Confocal; Microscopy, Electron, Scanning; Nanospheres; Particle Size; Plasmids; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; RNA, Small Interfering; Surface Properties; Transfection | 2010 |
A one-step modified method to reduce the burst initial release from PLGA microspheres.
Topics: Alginates; Biocompatible Materials; Chemistry, Pharmaceutical; Chitosan; Dentin-Bonding Agents; Drug Carriers; Drug Compounding; Drug Delivery Systems; Excipients; Glucuronic Acid; Hexuronic Acids; Lactic Acid; Methacrylates; Microspheres; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Porosity; Serum Albumin, Bovine; Solubility; Surface Properties | 2010 |
Evaluation of mucoadhesive PLGA microparticles for nasal immunization.
Topics: Administration, Intranasal; Animals; Chemistry, Pharmaceutical; Chitosan; Drug Carriers; Electrochemistry; Enzyme-Linked Immunosorbent Assay; Excipients; Female; Hepatitis B Surface Antigens; Immunoglobulin A; Immunoglobulin G; Lactic Acid; Mice; Mice, Inbred BALB C; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Mucins; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Tissue Adhesives; Vaccines | 2010 |
The effect of surface functionalization of PLGA nanoparticles by heparin- or chitosan-conjugated Pluronic on tumor targeting.
Topics: Animals; Cell Line, Tumor; Cell Survival; Chitosan; Drug Carriers; Heparin; Lactic Acid; Mice; Mice, Nude; Nanoparticles; Neoplasms; NIH 3T3 Cells; Poloxamer; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Surface Properties | 2010 |
Effectiveness of acidified sodium chlorite and other sanitizers to control Escherichia coli O157:H7 on tomato surfaces.
Topics: Anti-Bacterial Agents; Chemical Phenomena; Chitosan; Chlorides; Colony Count, Microbial; Disinfection; Escherichia coli O157; Foodborne Diseases; Fruit; Humans; Hydrogen-Ion Concentration; Lactic Acid; Phytic Acid; Pigmentation; Quality Control; Solanum lycopersicum; Surface Properties; Taste | 2010 |
Immobilization of Lactobacillus salivarius ATCC 11741 on loofa sponge coated with chitosan for lactic acid fermentation.
Topics: Cells, Immobilized; Chitosan; Fermentation; Industrial Microbiology; Lactic Acid; Lactobacillus | 2010 |
[Controlled release of siRNA nanoparticles loaded in a novel external stent prepared by emulsion electrospinning attenuates neointima hyperplasia in vein grafts].
Topics: Animals; Chitosan; Female; Graft Occlusion, Vascular; Hyperplasia; Lactic Acid; Male; Materials Testing; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Stents; Tunica Intima; Veins | 2009 |
A novel method for modifying AFM probe to investigate the interaction between biomaterial polymers (chitosan-coated PLGA) and mucin film.
Topics: Adhesiveness; Chitosan; Drug Carriers; Hydrophobic and Hydrophilic Interactions; Lactic Acid; Microscopy, Atomic Force; Mucins; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2010 |
Bone repair by cell-seeded 3D-bioplotted composite scaffolds made of collagen treated tricalciumphosphate or tricalciumphosphate-chitosan-collagen hydrogel or PLGA in ovine critical-sized calvarial defects.
Topics: Absorbable Implants; Animals; Bone Regeneration; Calcium Phosphates; Chitosan; Collagen; Disease Models, Animal; Female; Glycolates; Hydrogels; Lactic Acid; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Sheep; Skull; Time Factors; Tissue Scaffolds | 2010 |
The development and mechanism studies of cationic chitosan-modified biodegradable PLGA nanoparticles for efficient siRNA drug delivery.
Topics: Cell Line; Cell Survival; Chitosan; Drug Delivery Systems; Humans; Lactic Acid; Models, Biological; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; RNA, Small Interfering | 2010 |
Hybrid-modified poly(D,L-lactide-co-glycolide) nanospheres for a novel cellular drug delivery system.
Topics: Biocompatible Materials; Cell Culture Techniques; Cell Line, Tumor; Cell Survival; Chitosan; DNA; Drug Carriers; Drug Compounding; Gene Transfer Techniques; Humans; Lactic Acid; Luciferases; Nanospheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polylysine; Polysorbates; Surface Properties | 2010 |
Preparation and pharmacodynamics of stearic acid and poly (lactic-co-glycolic acid) grafted chitosan oligosaccharide micelles for 10-hydroxycamptothecin.
Topics: Antineoplastic Agents, Phytogenic; Biological Transport; Camptothecin; Carbodiimides; Cell Survival; Chemistry, Pharmaceutical; Chitosan; Dose-Response Relationship, Drug; Drug Carriers; Drug Compounding; Drug Stability; Hep G2 Cells; Humans; Hydrophobic and Hydrophilic Interactions; Kinetics; Lactic Acid; Magnetic Resonance Spectroscopy; Micelles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solubility; Stearic Acids; Technology, Pharmaceutical | 2010 |
In silico modelling of drug-polymer interactions for pharmaceutical formulations.
Topics: Biological Availability; Chemistry, Pharmaceutical; Chitosan; Dosage Forms; Excipients; Hydrophobic and Hydrophilic Interactions; Lactic Acid; Micelles; Microspheres; Molecular Dynamics Simulation; Pharmaceutical Preparations; Polymers | 2010 |
Chitosan film containing poly(D,L-lactic-co-glycolic acid) nanoparticles: a platform for localized dual-drug release.
Topics: Chitosan; Drug Compounding; Drug Delivery Systems; Drug Stability; Fluoresceins; Gold; Hydrophobic and Hydrophilic Interactions; Lactic Acid; Nanoparticles; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Surface Properties | 2010 |
Alginate-chitosan-PLGA composite microspheres enabling single-shot hepatitis B vaccination.
Topics: Alginates; Animals; Chitosan; Enzyme-Linked Immunosorbent Assay; Glucuronic Acid; Hepatitis Antibodies; Hepatitis B Vaccines; Hexuronic Acids; Lactic Acid; Mice; Microscopy, Electron, Scanning; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2010 |
Preparation and in-vitro/in-vivo evaluation of surface-modified poly (lactide-co-glycolide) fluorescent nanoparticles.
Topics: Animals; Biological Transport; Breast Neoplasms; Cell Line, Tumor; Chitosan; Coumarins; Drug Carriers; Female; Flow Cytometry; Fluorescence; Lactic Acid; Mice; Mice, Inbred BALB C; Microscopy, Electron, Scanning; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Spectrometry, Fluorescence; Surface Properties; Technology, Pharmaceutical; Thiazoles; Tissue Distribution | 2010 |
Nasal vaccination with N-trimethyl chitosan and PLGA based nanoparticles: nanoparticle characteristics determine quality and strength of the antibody response in mice against the encapsulated antigen.
Topics: Administration, Intranasal; Animals; Antibody Formation; Cells, Cultured; Chitosan; Dendritic Cells; Drug Carriers; Female; Humans; Immunoglobulin A, Secretory; Immunoglobulin G; Lactic Acid; Mice; Mice, Inbred BALB C; Nanoparticles; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Vaccination | 2010 |
A comparative study of seeding techniques and three-dimensional matrices for mesenchymal cell attachment.
Topics: Animals; Calcium Phosphates; Cell Adhesion; Cell Culture Techniques; Cell Line; Cell Survival; Chitosan; DNA; Kinetics; Lactic Acid; Mesenchymal Stem Cells; Mice; Polyesters; Polyglycolic Acid; Polymers; Tissue Scaffolds; Water | 2011 |
Use of tissue-engineered nerve grafts consisting of a chitosan/poly(lactic-co-glycolic acid)-based scaffold included with bone marrow mesenchymal cells for bridging 50-mm dog sciatic nerve gaps.
Topics: Animals; Bone Marrow Cells; Chitosan; Dogs; Immunohistochemistry; Lactic Acid; Mesenchymal Stem Cells; Microscopy; Microscopy, Electron, Transmission; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Tissue Engineering; Tissue Scaffolds | 2010 |
Immunopotentiation of hepatitis B vaccine using biodegradable polymers as an adjuvant.
Topics: Adjuvants, Immunologic; Animals; Chitosan; Delayed-Action Preparations; Glycolates; Hepatitis B Antibodies; Hepatitis B Surface Antigens; Hepatitis B Vaccines; Lactic Acid; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rats; Rats, Wistar | 2010 |
Administration routes affect the quality of immune responses: A cross-sectional evaluation of particulate antigen-delivery systems.
Topics: Adjuvants, Immunologic; Animals; Cells, Cultured; Chemistry, Pharmaceutical; Chitosan; Drug Administration Routes; Drug Carriers; Drug Delivery Systems; Female; Immunoglobulin G; Interferon-gamma; Kinetics; Lactic Acid; Liposomes; Mice; Mice, Inbred BALB C; Nanoparticles; Ovalbumin; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solubility; Spleen; Th1 Cells; Th2 Cells; Time Factors; Vaccines | 2010 |
Ciliary neurotrophic factor-coated polylactic-polyglycolic acid chitosan nerve conduit promotes peripheral nerve regeneration in canine tibial nerve defect repair.
Topics: Animals; Chitosan; Ciliary Neurotrophic Factor; Coated Materials, Biocompatible; Dogs; Guided Tissue Regeneration; Lactic Acid; Materials Testing; Nerve Regeneration; Peripheral Nerves; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Tibial Nerve | 2010 |
Fabrication of a two-level tumor bone repair biomaterial based on a rapid prototyping technique.
Topics: Absorption; Bone Neoplasms; Bone Substitutes; Calcium Phosphates; Chitosan; Computer-Aided Design; Giant Cell Tumor of Bone; Humans; Lactic Acid; Microscopy, Electron, Scanning; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Porosity; Tissue Engineering; Tissue Scaffolds | 2009 |
A temperature-sensitive drug release system based on phase-change materials.
Topics: Chitosan; Delayed-Action Preparations; Dextrans; Fatty Alcohols; Fluorescein-5-isothiocyanate; Gelatin; Lactic Acid; Phase Transition; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Temperature | 2010 |
In vivo uptake and acute immune response to orally administered chitosan and PEG coated PLGA nanoparticles.
Topics: Administration, Oral; Animals; Chitosan; Cytokines; Drug Delivery Systems; Female; Lactic Acid; Lipopolysaccharides; Mice; Mice, Inbred BALB C; Nanoparticles; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2010 |
Oral nuclear factor-κB decoy oligonucleotides delivery system with chitosan modified poly(D,L-lactide-co-glycolide) nanospheres for inflammatory bowel disease.
Topics: Animals; Chitosan; Drug Carriers; Inflammatory Bowel Diseases; Lactic Acid; Male; Nanospheres; NF-kappa B; Oligonucleotides; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Wistar | 2011 |
Microscopic and spectroscopic evaluation of novel PLGA-chitosan Nanoplexes as an ocular delivery system.
Topics: Animals; Chitosan; Drug Delivery Systems; Eye; Fluorescent Dyes; Humans; Lactic Acid; Materials Testing; Microscopy, Confocal; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Nanoparticles; Nanotechnology; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rabbits; Rhodamines; Spectrophotometry; Time Factors | 2011 |
Swellable hydrogel particles for controlled release pulmonary administration using propellant-driven metered dose inhalers.
Topics: Administration, Inhalation; Aerosol Propellants; Anti-Inflammatory Agents, Non-Steroidal; Chitosan; Curcumin; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Drug Stability; Hydrocarbons, Fluorinated; Hydrogels; Lactic Acid; Lung; Metered Dose Inhalers; Microspheres; Nanoparticles; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2011 |
Effect of surface-modified collagen on the adhesion, biocompatibility and differentiation of bone marrow stromal cells in poly(lactide-co-glycolide)/chitosan scaffolds.
Topics: Animals; Biocompatible Materials; Bone Marrow Cells; Cell Adhesion; Cell Differentiation; Chitosan; Collagen; Lactic Acid; Male; Nerve Growth Factor; Neurons; Osteoblasts; Osteogenesis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Stromal Cells; Surface Properties; Tissue Engineering | 2011 |
A novel route for the production of chitosan/poly(lactide-co-glycolide) graft copolymers for electrospinning.
Topics: Biocompatible Materials; Chitosan; Electrochemistry; Lactic Acid; Materials Testing; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rotation | 2010 |
Physicochemical characterization of protein-loaded pectin-chitosan nanoparticles prepared by polyelectrolyte complexation.
Topics: Chitosan; Chromatography, High Pressure Liquid; Electrochemistry; Electrolytes; Excipients; Lactic Acid; Nanoparticles; Ovalbumin; Pectins; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Proteins; Solvents; Ultrasonics | 2010 |
Investigation of the interaction of biodegradable micro- and nanoparticulate drug delivery systems with platelets.
Topics: Chitosan; Drug Carriers; Drug Delivery Systems; Humans; In Vitro Techniques; Lactic Acid; Microspheres; Nanoparticles; Particle Size; Platelet Aggregation; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solvents | 2011 |
Surface modification of poly(L-lactic acid) with biomolecules to promote endothelialization.
Topics: Biopolymers; Cell Adhesion; Cells, Cultured; Chitosan; Endothelial Cells; Gelatin; Humans; Lactic Acid; Polyesters; Polymers; Surface Properties | 2010 |
Seeding density matters: extensive intercellular contact masks the surface dependence of endothelial cell-biomaterial interactions.
Topics: Biocompatible Materials; Cell Adhesion; Cell Proliferation; Chitosan; Endothelial Cells; Gelatin; Humans; Lactic Acid; Materials Testing; Microscopy, Fluorescence; Polyesters; Polymers; Surface Properties; Time Factors | 2011 |
Comparative evaluation of in vitro parameters of tamoxifen citrate loaded poly(lactide-co-glycolide), poly(epsilon-caprolactone) and chitosan nanoparticles.
Topics: Biological Availability; Chitosan; Chromatography, High Pressure Liquid; Drug Compounding; Drug Delivery Systems; Electrochemistry; Estrogen Antagonists; Excipients; Lactic Acid; Microscopy, Electron, Scanning; Nanoparticles; Particle Size; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Tamoxifen | 2010 |
Electrospinning of chitosan derivative nanofibers with structural stability in an aqueous environment.
Topics: Animals; Biocompatible Materials; Cell Line; Cell Proliferation; Cell Survival; Chitosan; Humans; Lactic Acid; Nanofibers; Nanotechnology; Schwann Cells; Tissue Scaffolds; Water | 2011 |
Enhanced cellular association of paclitaxel delivered in chitosan-PLGA particles.
Topics: Adhesiveness; Animals; Antineoplastic Agents, Phytogenic; Boron Compounds; Cell Line, Tumor; Chitosan; Drug Carriers; Female; Inhibitory Concentration 50; Lactic Acid; Mammary Neoplasms, Animal; Mice; Microscopy, Confocal; Microspheres; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2011 |
Anti-inflammatory and antiangiogenic effects of nanoparticle-mediated delivery of a natural angiogenic inhibitor.
Topics: Angiogenesis Inhibitors; Animals; Anti-Inflammatory Agents; Blotting, Western; Capillary Permeability; Chemokine CCL2; Chitosan; Choroidal Neovascularization; Drug Delivery Systems; Enzyme-Linked Immunosorbent Assay; Fluorescein Angiography; Intercellular Adhesion Molecule-1; Intravitreal Injections; Lactic Acid; Male; Nanoparticles; Peptide Fragments; Plasminogen; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Inbred BN; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2011 |
High entrapment efficiency of chitosan/polylactic acid/tripolyphotspate nanosized microcapsules for rapamycin by an emulsion-evaporation approach.
Topics: Capsules; Chitosan; Drug Delivery Systems; Emulsions; Lactic Acid; Nanocapsules; Polyesters; Polymers; Polyphosphates; Sirolimus; Volatilization | 2010 |
Compatible ternary blends of chitosan/poly(vinyl alcohol)/poly(lactic acid) produced by oil-in-water emulsion processing.
Topics: Calorimetry, Differential Scanning; Chitosan; Emulsions; Lactic Acid; Microscopy, Electron, Scanning; Oils; Polyesters; Polymers; Polyvinyl Alcohol; Spectroscopy, Fourier Transform Infrared | 2011 |
Improvements in transfection efficiency with chitosan modified poly(DL-lactide-co-glycolide) nanospheres prepared by the emulsion solvent diffusion method, for gene delivery.
Topics: Cell Line, Tumor; Chitosan; Diffusion; Emulsions; Humans; Lactic Acid; Nanospheres; Plasmids; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solvents; Transfection | 2011 |
Surface characterisation of bioadhesive PLGA/chitosan microparticles produced by supercritical fluid technology.
Topics: Adhesiveness; Animals; Biocompatible Materials; Chitosan; Chromatography, Supercritical Fluid; Humans; Lactic Acid; Microscopy, Electron, Scanning; Mucins; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Surface Properties | 2011 |
PDLLA/chondroitin sulfate/chitosan/NGF conduits for peripheral nerve regeneration.
Topics: Animals; Biocompatible Materials; Chitosan; Chondroitin Sulfates; Lactic Acid; Materials Testing; Nerve Growth Factor; Nerve Regeneration; Neural Conduction; Peripheral Nerves; Polyesters; Polymers; Prostheses and Implants; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Spectroscopy, Fourier Transform Infrared; Tissue Scaffolds | 2011 |
Layer-by-layer assembly of chitosan and platelet monoclonal antibody to improve biocompatibility and release character of PLLA coated stent.
Topics: Antibodies, Monoclonal; Blood Platelets; Buffers; Cell Line; Cell Membrane; Cell Movement; Cell Shape; Chitosan; Coated Materials, Biocompatible; Endothelial Cells; Fluorescence; Humans; Hydrogen-Ion Concentration; Lactic Acid; Materials Testing; Partial Thromboplastin Time; Perfusion; Platelet Adhesiveness; Platelet Aggregation; Polyesters; Polymers; Stents | 2011 |
Effects of spray drying on physicochemical properties of chitosan acid salts.
Topics: Acetic Acid; Animals; Chemistry, Pharmaceutical; Chitosan; Lactic Acid; Palinuridae; Particle Size; Salts | 2011 |
[Design and biological evaluation of poly-lactic-co-glycolic acid (PLGA) mesh/collagen-chitosan hybrid scaffold (CCS) as a dermal substitute].
Topics: Animals; Cells, Cultured; Chitosan; Collagen; Extracellular Matrix; Lactic Acid; Male; Materials Testing; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Prosthesis Design; Rats; Rats, Sprague-Dawley; Regeneration; Skin, Artificial; Tissue Engineering; Tissue Scaffolds | 2011 |
[PLA-O-CMC nanoparticles: HGF loading and delivery behaviors in vitro].
Topics: Chitosan; Drug Carriers; Hepatocyte Growth Factor; Lactic Acid; Nanoparticles; Oxygen; Polyesters; Polymers | 2011 |
Three-dimensional honeycomb-patterned chitosan/poly(L-lactic acid) scaffolds with improved mechanical and cell compatibility.
Topics: 3T3 Cells; Animals; Cell Adhesion; Cell Proliferation; Cell Survival; Chitosan; Elastic Modulus; Extracellular Matrix; Fibroblasts; Lactic Acid; Materials Testing; Mice; Polyesters; Polymers; Porosity; Stress, Mechanical; Tissue Scaffolds | 2011 |
Chitosan-modified poly(D,L-lactide-co-glycolide) nanospheres for plasmid DNA delivery and HBV gene-silencing.
Topics: Cell Survival; Chitosan; DNA; Drug Carriers; Electrophoresis, Agar Gel; Gene Silencing; Gene Transfer Techniques; Hep G2 Cells; Hepatitis B virus; Humans; Lactic Acid; Microscopy, Confocal; Microscopy, Electron, Transmission; Nanoparticles; Particle Size; Plasmids; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Surface Properties; Transfection | 2011 |
Chitosan/PLGA particles for controlled release of α-tocopherol in the GI tract via oral administration.
Topics: Administration, Oral; alpha-Tocopherol; Animals; Chitosan; Gastrointestinal Tract; Hydrogen-Ion Concentration; In Vitro Techniques; Lactic Acid; Microscopy, Electron, Transmission; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rabbits | 2011 |
Enhancing the stiffness of electrospun nanofiber scaffolds with a controlled surface coating and mineralization.
Topics: Chitosan; Durapatite; Electrochemistry; Heparin; Lactic Acid; Nanofibers; Nanotechnology; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Surface Properties | 2011 |
Biochemical and pathological evidences on the benefit of a new biodegradable nanoparticles of probiotic extract in murine colitis.
Topics: Animals; Chitosan; Colitis; Cytokines; Dexamethasone; Disease Models, Animal; Dose-Response Relationship, Drug; Freeze Drying; Inflammation Mediators; Lactic Acid; Lipid Peroxidation; Male; Nanoparticles; Pilot Projects; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Probiotics; Rats; Rats, Wistar; Trinitrobenzenesulfonic Acid | 2012 |
Tissue slice model of human lung cancer to investigate telomerase inhibition by nanoparticle delivery of antisense 2'-O-methyl-RNA.
Topics: Carcinoma, Non-Small-Cell Lung; Chitosan; Humans; Lactic Acid; Lung Neoplasms; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; RNA, Antisense; Telomerase; Tissue Culture Techniques | 2011 |
Incorporation of PLGA nanoparticles into porous chitosan-gelatin scaffolds: influence on the physical properties and cell behavior.
Topics: Cell Adhesion; Cell Differentiation; Cell Line; Cell Survival; Chitosan; Compressive Strength; Gelatin; Humans; Lactic Acid; Nanoparticles; Osteoblasts; Osteogenesis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Porosity; Tissue Scaffolds | 2011 |
Structural characterization of chitin and chitosan obtained by biological and chemical methods.
Topics: Acids; Alkalies; Animals; Bioreactors; Chitin; Chitosan; Crystallography, X-Ray; Fermentation; Hydrogen-Ion Concentration; Industrial Microbiology; Lactic Acid; Lactobacillus plantarum; Penaeidae; Waste Products; Xanthophylls | 2011 |
Preparation and characterization of electrospun PCL/PLGA membranes and chitosan/gelatin hydrogels for skin bioengineering applications.
Topics: Biocompatible Materials; Cell Adhesion; Cell Proliferation; Chitosan; Fibroblasts; Gelatin; Humans; Hydrogels; Lactic Acid; Microscopy, Electron, Scanning; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Skin; Stress, Mechanical; Time Factors; Tissue Engineering | 2011 |
A facile method for preparing biodegradable chitosan derivatives with low grafting degree of poly(lactic acid).
Topics: Biocompatible Materials; Biodegradation, Environmental; Carbodiimides; Chitosan; Humans; Hydrophobic and Hydrophilic Interactions; Lactic Acid; Magnetic Resonance Spectroscopy; Polyesters; Polymers; Solubility; Spectroscopy, Fourier Transform Infrared; Tissue Engineering; Trypsin | 2011 |
Biocompatible polymer coating of titania nanotube arrays for improved drug elution and osteoblast adhesion.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cell Adhesion; Cells, Cultured; Chitosan; Coated Materials, Biocompatible; Drug Carriers; Drug Delivery Systems; Humans; Indomethacin; Lactic Acid; Materials Testing; Nanotubes; Osteoblasts; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Surface Properties; Titanium | 2012 |
Characterisation and stability studies of a hydrophilic decapeptide in different adjuvant drug delivery systems: a comparative study of PLGA nanoparticles versus chitosan-dextran sulphate microparticles versus DOTAP-liposomes.
Topics: Adjuvants, Pharmaceutic; Chitosan; Dextran Sulfate; Drug Stability; Fatty Acids, Monounsaturated; Freeze Drying; Hydrophobic and Hydrophilic Interactions; Lactic Acid; Liposomes; Nanoparticles; Oligopeptides; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Quaternary Ammonium Compounds | 2011 |
Joint use of a chitosan/PLGA scaffold and MSCs to bridge an extra large gap in dog sciatic nerve.
Topics: Animals; Biocompatible Materials; Bone Marrow; Chitosan; Dogs; Lactic Acid; Mesenchymal Stem Cell Transplantation; Nerve Regeneration; Peripheral Nerve Injuries; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Sciatic Nerve; Tissue Engineering; Tissue Scaffolds; Tissue Transplantation; Wound Healing | 2012 |
Long circulating chitosan/PEG blended PLGA nanoparticle for tumor drug delivery.
Topics: Adsorption; Animals; Antineoplastic Agents; Biological Transport; Capsules; Cattle; Cell Line, Tumor; Chitosan; Drug Carriers; Drug Stability; Female; Humans; Hydrophobic and Hydrophilic Interactions; Lactic Acid; Macrophages; Mice; Molecular Weight; Nanoparticles; Paclitaxel; Phagocytosis; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Serum Albumin, Bovine | 2011 |
The suppression of IgE-mediated histamine release from mast cells following exocytic exclusion of biodegradable polymeric nanoparticles.
Topics: Animals; Blotting, Western; Cell Line, Tumor; Chitosan; Exocytosis; Histamine; Immunoglobulin E; Lactic Acid; Male; Mast Cells; Mice; Mice, Inbred C57BL; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats | 2012 |
PLGA, PLGA-TMC and TMC-TPP nanoparticles differentially modulate the outcome of nasal vaccination by inducing tolerance or enhancing humoral immunity.
Topics: Administration, Intranasal; Antibody Formation; CD4-Positive T-Lymphocytes; Cell Proliferation; Chitosan; Hypersensitivity, Delayed; Lactic Acid; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polyphosphates; Vaccines | 2011 |
[Vascularization of poly-lactic-co-glycolic acid knitted mesh/collagen-chitosan hybrid scaffold].
Topics: Animals; Biocompatible Materials; Chitosan; Collagen; Lactic Acid; Male; Materials Testing; Neovascularization, Physiologic; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Tissue Engineering; Tissue Scaffolds | 2011 |
Poly(lactic acid)/N-maleoylchitosan core-shell capsules: preparation and drug release properties.
Topics: Chitosan; Lactic Acid; Microscopy; Particle Size; Polyesters; Polymers | 2012 |
Intranasal delivery of cationic PLGA nano/microparticles-loaded FMDV DNA vaccine encoding IL-6 elicited protective immunity against FMDV challenge.
Topics: Adjuvants, Immunologic; Administration, Intranasal; Animals; Antibodies, Neutralizing; Capsid Proteins; Cattle; Chitosan; Cytokines; Dendritic Cells; Drug Carriers; Female; Foot-and-Mouth Disease Virus; Guinea Pigs; Immunoglobulin A, Secretory; Immunoglobulin G; Interleukin-6; Lactic Acid; Microtechnology; Mucous Membrane; Nanoparticles; Plasmids; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; T-Lymphocytes; Transcriptome; Vaccines, DNA; Viral Vaccines | 2011 |
Influence of surface charge on the potential toxicity of PLGA nanoparticles towards Calu-3 cells.
Topics: Bronchi; Cell Line; Cell Survival; Chitosan; Humans; Interleukin-6; Interleukin-8; Lactic Acid; Microscopy, Confocal; Nanoparticles; Poloxamer; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polyvinyl Alcohol; Rhodamines; Static Electricity; Surface Properties | 2011 |
Synergistic stimuli by hydrodynamic pressure and hydrophilic coating on PLGA scaffolds for extracellular matrix synthesis of engineered cartilage.
Topics: Animals; Cartilage; Cell Proliferation; Cell Survival; Chitosan; Chondrocytes; Coated Materials, Biocompatible; Extracellular Matrix; Hyaluronic Acid; Hydrodynamics; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Knee Joint; Lactic Acid; Materials Testing; Physical Stimulation; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Porosity; Pressure; Surface Properties; Swine; Tissue Engineering; Tissue Scaffolds; Water | 2012 |
Controlled release pulmonary administration of curcumin using swellable biocompatible microparticles.
Topics: Administration, Inhalation; Aerosols; Animals; Biocompatible Materials; Cell Culture Techniques; Chitosan; Curcumin; Delayed-Action Preparations; Drug Carriers; Hydrogels; Lactic Acid; Lung; Macrophages, Alveolar; Mice; Microspheres; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Powders; Tumor Necrosis Factor-alpha | 2012 |
Use of a short peptide as a building block in the layer-by-layer assembly of biomolecules on polymeric surfaces.
Topics: Adsorption; alpha-MSH; Chitosan; Humans; Hyaluronic Acid; Hydrophobic and Hydrophilic Interactions; Lactic Acid; Lipids; Models, Molecular; Molecular Dynamics Simulation; Molecular Weight; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Protein Conformation; Protein Structure, Secondary; Static Electricity; Surface Properties | 2012 |
Preparation and evaluation of mannose receptor mediated macrophage targeting delivery system.
Topics: Animals; Cell Line; Chemistry, Pharmaceutical; Chitosan; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Flow Cytometry; Kinetics; Lactic Acid; Lectins, C-Type; Macrophages; Magnetic Resonance Spectroscopy; Mannose; Mannose Receptor; Mannose-Binding Lectins; Mice; Microscopy, Confocal; Nanoparticles; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Receptors, Cell Surface; Solubility; Spectrometry, Fluorescence; Technology, Pharmaceutical | 2011 |
Preparation and characterization of insulin-loaded bioadhesive PLGA nanoparticles for oral administration.
Topics: Adhesiveness; Administration, Oral; Animals; Biological Availability; Caco-2 Cells; Cations; Cell Line, Tumor; Chemical Phenomena; Chemistry, Pharmaceutical; Chitosan; Drug Carriers; Drug Delivery Systems; Humans; Insulin; Lactic Acid; Male; Mice; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley | 2012 |
Fabrication and characterization of poly(L-lactide-co-glycolide) knitted mesh-reinforced collagen-chitosan hybrid scaffolds for dermal tissue engineering.
Topics: Animals; Cattle; Chitosan; Collagen; Freeze Drying; Lactic Acid; Male; Materials Testing; Mechanical Phenomena; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymerase Chain Reaction; Rats; Skin; Tissue Engineering; Tissue Scaffolds | 2012 |
Development of an indirect stereolithography technology for scaffold fabrication with a wide range of biomaterial selectivity.
Topics: Alginates; Biocompatible Materials; Cells, Cultured; Chitosan; Equipment Design; Glucuronic Acid; Hexuronic Acids; Humans; Imaging, Three-Dimensional; Lactic Acid; Magnetic Resonance Spectroscopy; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Porosity; Tissue Engineering; Tissue Scaffolds | 2012 |
Paclitaxel loaded folic acid targeted nanoparticles of mixed lipid-shell and polymer-core: in vitro and in vivo evaluation.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Chemistry, Pharmaceutical; Chitosan; Drug Carriers; Drug Compounding; Drug Delivery Systems; Female; Folic Acid; HeLa Cells; Humans; Lactic Acid; Lipids; Mice; Mice, SCID; Nanoparticles; Paclitaxel; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Tissue Distribution | 2012 |
Low molecular-weight chitosan as a pH-sensitive stealth coating for tumor-specific drug delivery.
Topics: Cell Line, Tumor; Cell Survival; Chitosan; Drug Carriers; Humans; Hydrogen-Ion Concentration; Lactic Acid; Microscopy, Confocal; Molecular Structure; Molecular Weight; Nanoparticles; Paclitaxel; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2012 |
Endocytosis-like uptake of surface-modified drug nanocarriers into giant unilamellar vesicles.
Topics: Chemistry, Physical; Chitosan; Drug Carriers; Endocytosis; Lactic Acid; Microscopy, Confocal; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polysorbates; Surface Properties; Unilamellar Liposomes | 2012 |
Minimizing acylation of peptides in PLGA microspheres.
Topics: Acylation; Animals; Calcitonin; Cations, Divalent; Chitosan; Drug Carriers; Drug Stability; Excipients; Glucose; Humans; Lactic Acid; Octreotide; Parathyroid Hormone; Peptides; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Salts | 2012 |
Pulmonary delivery and tissue distribution of aerosolized antisense 2'-O-Methyl RNA containing nanoplexes in the isolated perfused and ventilated rat lung.
Topics: Aerosols; Animals; Chitosan; Lactic Acid; Lung; Male; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Wistar; RNA, Antisense; Tissue Distribution | 2012 |
PLGA-based nanoparticles: effect of chitosan in the aggregate stabilization. A dielectric relaxation spectroscopy study.
Topics: Chitosan; Drug Delivery Systems; Lactic Acid; Nanoparticles; Nanotechnology; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2012 |
Preparation of biocompatible chitosan grafted poly(lactic acid) nanoparticles.
Topics: Biocompatible Materials; Cell Line; Chitosan; Hemolysis; Humans; Lactic Acid; Nanoparticles; Polyesters; Polymers | 2012 |
Dry powder inhaler formulation of lipid-polymer hybrid nanoparticles via electrostatically-driven nanoparticle assembly onto microscale carrier particles.
Topics: Adsorption; Aerosols; Chitosan; Cross-Linking Reagents; Dextran Sulfate; Drug Carriers; Drug Compounding; Dry Powder Inhalers; Excipients; Glycine max; Lactic Acid; Lecithins; Nanocomposites; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polyphosphates; Static Electricity; Technology, Pharmaceutical | 2012 |
Full factorial design, physicochemical characterisation and biological assessment of cyclosporine A loaded cationic nanoparticles.
Topics: Animals; Cations; Chitosan; Cyclosporine; Drug Carriers; Drug Compounding; Emulsions; Epithelial Cells; Humans; Immunosuppressive Agents; Jurkat Cells; Lactic Acid; Mucus; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solvents; Static Electricity; Swine; Tears | 2012 |
A chitosan lactate/poloxamer 407-based matrix containing Eudragit RS microparticles for vaginal delivery of econazole: design and in vitro evaluation.
Topics: Acrylic Resins; Adhesiveness; Administration, Intravaginal; Antifungal Agents; Calorimetry, Differential Scanning; Candida albicans; Chitosan; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Econazole; Emulsions; Lactic Acid; Microspheres; Poloxamer; Time Factors | 2013 |
Design and evaluation of inhalable chitosan-modified poly (DL-lactic-co-glycolic acid) nanocomposite particles.
Topics: Absorption; Administration, Inhalation; Animals; Calcitonin; Chemistry, Pharmaceutical; Chitosan; Hypocalcemia; Lactic Acid; Lung; Male; Nanocomposites; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Powders; Rats; Rats, Wistar; Technology, Pharmaceutical | 2012 |
Enhancement of osteogenic differentiation of human adipose derived stem cells by the controlled release of platelet lysates from hybrid scaffolds produced by supercritical fluid foaming.
Topics: Adipose Tissue; Adult; Alkaline Phosphatase; Blood Platelets; Cell Proliferation; Cells, Cultured; Chitosan; Chondroitin Sulfates; Core Binding Factor Alpha 1 Subunit; Delayed-Action Preparations; Female; Gene Expression Regulation, Developmental; Humans; Lactic Acid; Middle Aged; Nanoparticles; Osteoblasts; Osteocalcin; Osteogenesis; Platelet-Derived Growth Factor; Polyesters; Polymers; Stem Cells; Tissue Engineering; Tissue Scaffolds | 2012 |
Differential functional effects of biomaterials on dendritic cell maturation.
Topics: Apoptosis; Biocompatible Materials; Cell Adhesion; Cell Differentiation; Cell Movement; Cell Proliferation; Cell Shape; Chitosan; Cytokines; Dendritic Cells; Endocytosis; Flow Cytometry; Fluorescence; Histocompatibility Antigens Class II; Humans; Hyaluronic Acid; Inflammation Mediators; Lactic Acid; Lipopolysaccharides; Photoelectron Spectroscopy; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Receptors, Cell Surface; Sepharose; Surface Properties; T-Lymphocytes; Transcription Factor RelA | 2012 |
Fabrication of aligned poly(lactic acid)-chitosan nanofibers by novel parallel blade collector method for skin tissue engineering.
Topics: Cells, Cultured; Chitosan; Equipment Design; Equipment Failure Analysis; Fibroblasts; Humans; Lactic Acid; Materials Testing; Molecular Conformation; Nanostructures; Nanotechnology; Particle Size; Polyesters; Polymers; Skin; Surface Properties; Tissue Engineering; Tissue Scaffolds | 2012 |
Chitosan/PLA nanoparticles as a novel carrier for the delivery of anthraquinone: synthesis, characterization and in vitro cytotoxicity evaluation.
Topics: Annexin A5; Anthraquinones; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Chitosan; DNA Fragmentation; DNA, Neoplasm; Drug Carriers; Drug Compounding; Drug Delivery Systems; Electrophoresis, Agar Gel; Humans; Lactic Acid; Membrane Potential, Mitochondrial; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Nanoparticles; Necrosis; Particle Size; Polyesters; Polymers; Tetrazolium Salts; Thiazoles | 2013 |
Prolonged gene silencing by siRNA/chitosan-g-deoxycholic acid polyplexes loaded within biodegradable polymer nanoparticles.
Topics: Biological Transport; Cell Line, Tumor; Cell Survival; Chitosan; Deoxycholic Acid; Gene Silencing; Green Fluorescent Proteins; Humans; Lactic Acid; Nanoparticles; Oligosaccharides; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; RNA, Small Interfering; Transfection | 2012 |
Drug delivery to inflamed colon by nanoparticles: comparison of different strategies.
Topics: Animals; Caco-2 Cells; Chitosan; Colitis; Cytokines; Dextran Sulfate; Drug Carriers; Ethylene Oxide; Female; Humans; Inflammatory Bowel Diseases; Intestinal Absorption; Lactic Acid; Lactones; Mannose; Mice; Mice, Inbred C57BL; Nanoparticles; Ovalbumin; Polyethylene Glycols; Polyglactin 910; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymethacrylic Acids | 2013 |
Modification of the release characteristics of estradiol encapsulated in PLGA particles via surface coating.
Topics: Chemistry, Pharmaceutical; Chitosan; Coated Materials, Biocompatible; Delayed-Action Preparations; Drug Carriers; Drug Compounding; Estradiol; Gelatin; Kinetics; Lactic Acid; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solubility; Surface Properties; Technology, Pharmaceutical | 2012 |
Inactivation of salmonella on tomato stem scars by edible chitosan and organic Acid coatings.
Topics: Acetic Acid; Anti-Bacterial Agents; Chitosan; Colony Count, Microbial; Consumer Product Safety; Dose-Response Relationship, Drug; Food Contamination; Food Preservation; Humans; Lactic Acid; Levulinic Acids; Plant Stems; Salmonella; Salmonella Food Poisoning; Solanum lycopersicum | 2012 |
Chemico-physical investigation of tenofovir loaded polymeric nanoparticles.
Topics: Adenine; Anti-HIV Agents; Chitosan; Drug Carriers; Lactic Acid; Nanoparticles; Organophosphonates; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Tenofovir | 2012 |
Electrospun poly(lactic acid)/chitosan core-shell structure nanofibers from homogeneous solution.
Topics: Animals; Cell Adhesion; Cells, Cultured; Chitosan; Cross-Linking Reagents; Electrochemistry; Fibroblasts; Lactic Acid; Membranes, Artificial; Mice; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Nanofibers; Polyesters; Polymers; Spectroscopy, Fourier Transform Infrared; Tissue Engineering; X-Ray Diffraction | 2012 |
One-pot synthesis of chitosan-g-(PEO-PLLA-PEO) via "click" chemistry and "SET-NRC" reaction.
Topics: Biocompatible Materials; Chitosan; Click Chemistry; Lactic Acid; Magnetic Resonance Spectroscopy; Morphinans; Polyesters; Polymers | 2012 |
Monodisperse double-walled microspheres loaded with chitosan-p53 nanoparticles and doxorubicin for combined gene therapy and chemotherapy.
Topics: Antibiotics, Antineoplastic; Chitosan; DNA; Doxorubicin; Drug Carriers; Drug Delivery Systems; Genetic Therapy; Lactic Acid; Microspheres; Nanoparticles; Plasmids; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Tumor Suppressor Protein p53 | 2012 |
[Preparation and biocompatibility of a novel biomimetic osteochondral scaffold: collagen-chitosan/nano-hydroxyapatite-collagen-polylactic acid].
Topics: Animals; Biocompatible Materials; Cell Proliferation; Cells, Cultured; Chitosan; Collagen; Durapatite; Female; Lactic Acid; Male; Materials Testing; Mesenchymal Stem Cells; Mice; Microscopy, Electron, Scanning; Polyesters; Polymers; Rabbits; Tissue Engineering; Tissue Scaffolds; Toxicity Tests, Acute | 2012 |
Comparative studies on chitosan and polylactic-co-glycolic acid incorporated nanoparticles of low molecular weight heparin.
Topics: Cell Line; Cell Survival; Chitosan; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Emulsions; Epithelial Cells; Feasibility Studies; Heparin, Low-Molecular-Weight; Humans; Lactic Acid; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2012 |
Electrospun Chitosan-graft-PLGA nanofibres with significantly enhanced hydrophilicity and improved mechanical property.
Topics: Chitosan; Hydrophobic and Hydrophilic Interactions; Lactic Acid; Nanofibers; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2013 |
Chitosan-coated PLGA nanoparticles: a sustained drug release strategy for cell cultures.
Topics: Animals; Cell Culture Techniques; Cell Proliferation; Cells, Cultured; Chitosan; Coated Materials, Biocompatible; Cytochrome P-450 CYP3A; Delayed-Action Preparations; Dexamethasone; Endocytosis; Enzyme Induction; Fibroblasts; Hepatocytes; Humans; Lactic Acid; Mice; Nanoparticles; Osmosis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Static Electricity; Time Factors | 2013 |
Preparation and hydrolytic erosion of differently structured PLGA nanoparticles with chitosan modification.
Topics: Chitosan; Hydrogen-Ion Concentration; Hydrolysis; Lactic Acid; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Water | 2013 |
In vitro degradation and drug release of a biodegradable tissue adhesive based on functionalized 1,2-ethylene glycol bis(dilactic acid) and chitosan.
Topics: Chitosan; Chromatography, High Pressure Liquid; Ethylene Glycol; In Vitro Techniques; Lactic Acid; Microbial Sensitivity Tests; Microscopy, Electron, Scanning; Spectroscopy, Fourier Transform Infrared; Tensile Strength; Tissue Adhesives | 2013 |
Improvement of therapeutic efficacy of PLGA nanoformulation of siRNA targeting anti-apoptotic Bcl-2 through chitosan coating.
Topics: Animals; Cell Line, Tumor; Cell Survival; Chitosan; Female; Gene Silencing; Genes, bcl-2; Humans; Lactic Acid; Male; Mice; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Proto-Oncogene Proteins c-bcl-2; RNA, Small Interfering; Tumor Burden; Xenograft Model Antitumor Assays | 2013 |
Chitosan rate of uptake in HEK293 cells is influenced by soluble versus microparticle state and enhanced by serum-induced cell metabolism and lactate-based media acidification.
Topics: Carbohydrate Conformation; Chitosan; Culture Media; Fluorescent Dyes; HEK293 Cells; Humans; Hydrogen-Ion Concentration; Lactic Acid; Light; Microscopy, Confocal; Microscopy, Fluorescence; Particle Size; Rhodamines; Scattering, Radiation; Serum; Solubility; Spectroscopy, Fourier Transform Infrared | 2013 |
Multilayered hierarchical capsules providing cell adhesion sites.
Topics: Alginates; Animals; Biocompatible Materials; Capsules; Cell Adhesion; Cell Proliferation; Cell Survival; Cells, Cultured; Cells, Immobilized; Chitosan; Glucuronic Acid; Hexuronic Acids; L Cells; Lactic Acid; Mice; Particle Size; Polyesters; Polylysine; Polymers | 2013 |
Comparison of PLGA and lecithin/chitosan nanoparticles for dermal targeting of betamethasone valerate.
Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents; Betamethasone Valerate; Chemistry, Pharmaceutical; Chitosan; Dermis; Drug Delivery Systems; Epidermis; Lactic Acid; Lecithins; Male; Nanoparticles; Particle Size; Permeability; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Wistar; Skin Absorption | 2013 |
Chitosan-modified PLGA nanoparticles with versatile surface for improved drug delivery.
Topics: Antimetabolites, Antineoplastic; Chemistry, Pharmaceutical; Chitosan; Delayed-Action Preparations; Drug Carriers; Fluorouracil; Hydrogen-Ion Concentration; Kinetics; Lactic Acid; Nanoparticles; Nanotechnology; Photoelectron Spectroscopy; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solubility; Spectroscopy, Fourier Transform Infrared; Surface Properties; Technology, Pharmaceutical | 2013 |
In vitro analysis regarding the safety of components used in a film-based therapeutic system loaded with meglumine antimoniate and its activity toward Leishmania major experimental infections: a preliminary study.
Topics: Antiprotozoal Agents; Cell Line; Cell Survival; Chitosan; Cicatrix; Drug Carriers; Excipients; Fibroblasts; Humans; Immunomodulation; Interleukins; Lactic Acid; Leishmania major; Leishmaniasis, Cutaneous; Macrophages; Meglumine; Meglumine Antimoniate; Organometallic Compounds; Pilot Projects; Povidone; Wound Healing | 2013 |
Spray-dried chitosan microparticles for cellular delivery of an antigenic protein: physico-chemical properties and cellular uptake by dendritic cells and macrophages.
Topics: Animals; Antigens; Cell Survival; Cells, Cultured; Chitosan; Dendritic Cells; Drug Delivery Systems; Hydrogen-Ion Concentration; Lactic Acid; Macrophages; Mice; Microspheres; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Proteins; Serum Albumin, Bovine | 2013 |
Poly (lactic acid)-chitosan-collagen composite nanofibers as substrates for blood outgrowth endothelial cells.
Topics: Animals; Blood Cells; Cell Adhesion; Cell Culture Techniques; Cell Proliferation; Cell Shape; Cell Survival; Cells, Cultured; Chitosan; Collagen; Culture Media; Endothelial Cells; Lactic Acid; Nanofibers; Nitric Oxide Synthase Type III; Polyesters; Polymers; Rats; Regenerative Medicine; Spectroscopy, Fourier Transform Infrared; Tissue Scaffolds | 2013 |
Fabrication and characterization of heparin-grafted poly-L-lactic acid-chitosan core-shell nanofibers scaffold for vascular gasket.
Topics: Biocompatible Materials; Blood Coagulation Tests; Blood Vessel Prosthesis; Carbohydrate Sequence; Cell Line; Cell Survival; Chitosan; Electrochemical Techniques; Heparin; Humans; Lactic Acid; Molecular Sequence Data; Nanofibers; Polyesters; Polymers; Surface Properties; Tissue Scaffolds | 2013 |
Synergistic effects of lactic acid and sodium dodecyl sulfate to decontaminate Escherichia coli O157:H7 on cattle hide sections.
Topics: Acetic Acid; Animals; Anti-Bacterial Agents; Cattle; Chitosan; Colony Count, Microbial; Decontamination; Drug Synergism; Escherichia coli O157; Lactic Acid; Skin; Sodium Dodecyl Sulfate | 2013 |
The roles of knitted mesh-reinforced collagen-chitosan hybrid scaffold in the one-step repair of full-thickness skin defects in rats.
Topics: Animals; Bandages; Chitosan; Collagen Type I; Equipment Design; Equipment Failure Analysis; Lactic Acid; Male; Materials Testing; Nanofibers; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Skin; Skin, Artificial; Tissue Scaffolds; Treatment Outcome; Wounds, Penetrating | 2013 |
Rapidly stopping hemorrhage by enhancing blood clotting at an opened wound using chitosan/polylactic acid/polycaprolactone wound dressing device.
Topics: Anti-Bacterial Agents; Bacterial Infections; Bandages; Blood Coagulation; Chitosan; Doxycycline; Drug Carriers; Equipment Design; Hemostatics; Humans; Lactic Acid; Polyesters; Polymers; Postoperative Hemorrhage; Sodium Glutamate; Surgical Wound Infection; Treatment Outcome; Wound Closure Techniques | 2013 |
Preparation, characterization, and in vitro and in vivo investigation of chitosan-coated poly (d,l-lactide-co-glycolide) nanoparticles for intestinal delivery of exendin-4.
Topics: Amiloride; Animals; Cell Survival; Chitosan; Chlorpromazine; Dogs; Drug Carriers; Exenatide; Intestinal Absorption; Lactic Acid; Madin Darby Canine Kidney Cells; Male; Models, Biological; Nanoparticles; Particle Size; Peptides; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Wistar; Spectrometry, Fluorescence; Venoms | 2013 |
Ultrasound-modulated shape memory and payload release effects in a biodegradable cylindrical rod made of chitosan-functionalized PLGA microspheres.
Topics: Biocompatible Materials; Chitosan; Lactic Acid; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Ultrasonics | 2013 |
Effects of chemically modified nanostructured PLGA on functioning of lung and breast cancer cells.
Topics: Alginates; Analysis of Variance; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Chitosan; Female; Glucuronic Acid; Hexuronic Acids; Humans; Lactic Acid; Lung Neoplasms; Nanostructures; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Surface Properties | 2013 |
Shear thinning three-dimensional colloidal assemblies of chitosan and poly(lactic acid) nanoparticles.
Topics: Chitosan; Colloids; Lactic Acid; Nanoparticles; Particle Size; Polyesters; Polymers; Surface Properties | 2013 |
Mechanisms of chitosan-coated poly(lactic-co-glycolic acid) nanoparticles for improving oral absorption of 7-ethyl-10-hydroxycamptothecin.
Topics: Absorption; Animals; Caco-2 Cells; Calorimetry, Differential Scanning; Camptothecin; Cell Death; Chitosan; Coated Materials, Biocompatible; Coumarins; Enterocytes; HT29 Cells; Humans; Intestines; Irinotecan; Kinetics; Lactic Acid; Male; Nanoparticles; Particle Size; Perfusion; Permeability; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Rhodamine 123; Spectroscopy, Fourier Transform Infrared; Static Electricity; X-Ray Diffraction | 2013 |
Toxicity of surface-modified PLGA nanoparticles toward lung alveolar epithelial cells.
Topics: Cell Line, Tumor; Cell Survival; Chitosan; Cytokines; Epithelial Cells; Humans; L-Lactate Dehydrogenase; Lactic Acid; Nanoparticles; Poloxamer; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polyvinyl Alcohol; Pulmonary Alveoli; Surface Properties | 2013 |
siRNA-chitosan complexes in poly(lactic-co-glycolic acid) nanoparticles for the silencing of aquaporin-1 in cancer cells.
Topics: Aquaporin 1; Chitosan; HeLa Cells; Humans; Lactic Acid; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; RNA, Small Interfering | 2013 |
Polysaccharide-modified scaffolds for controlled lentivirus delivery in vitro and after spinal cord injury.
Topics: Animals; Chitosan; Female; Gene Transfer Techniques; Genetic Therapy; HEK293 Cells; Heparin; Humans; Hyaluronic Acid; Lactic Acid; Lentivirus; Luciferases; Mice; Mice, Inbred C57BL; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Spinal Cord Injuries; Tissue Scaffolds | 2013 |
Fabrication and evaluation of a sustained-release chitosan-based scaffold embedded with PLGA microspheres.
Topics: Animals; Cattle; Chitosan; Delayed-Action Preparations; Diffusion; Drug Delivery Systems; Lactic Acid; Microscopy, Electron, Scanning; Microspheres; Neural Stem Cells; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Porosity; Serum Albumin, Bovine; Tissue Scaffolds; Water | 2013 |
Functionalization of 3D scaffolds with protein-releasing biomaterials for intracellular delivery.
Topics: Animals; Bacterial Proteins; Biocompatible Materials; Cells, Cultured; Chitosan; Escherichia coli; Fibroblasts; HeLa Cells; Humans; Inclusion Bodies; Lactic Acid; Mice; NIH 3T3 Cells; Polyesters; Polymers; Tissue Scaffolds | 2013 |
Development and characterization of surface modified PLGA nanoparticles for nasal vaccine delivery: effect of mucoadhesive coating on antigen uptake and immune adjuvant activity.
Topics: Adjuvants, Immunologic; Administration, Intranasal; Animals; Chitosan; Drug Delivery Systems; Excipients; Female; Hepatitis B Surface Antigens; Hepatitis B Vaccines; Humans; Immunity, Mucosal; Lactic Acid; Male; Mice; Mice, Inbred BALB C; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rabbits; Tissue Distribution | 2013 |
Poly(lactic-co-glycolic) acid/nanohydroxyapatite scaffold containing chitosan microspheres with adrenomedullin delivery for modulation activity of osteoblasts and vascular endothelial cells.
Topics: Adrenomedullin; Biocompatible Materials; Chitosan; Drug Delivery Systems; Endothelial Cells; Human Umbilical Vein Endothelial Cells; Humans; Lactic Acid; Microspheres; Osteoblasts; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Porosity; Tissue Engineering | 2013 |
Fabrication of nano-fibrous poly(L-lactic acid) scaffold reinforced by surface modified chitosan micro-fiber.
Topics: Absorption; Biocompatible Materials; Biomechanical Phenomena; Cell Line; Chitosan; Lactic Acid; Materials Testing; Nanofibers; Polyesters; Polymers; Porosity; Proteins; Spectroscopy, Fourier Transform Infrared; Surface Properties; Tissue Engineering; Tissue Scaffolds | 2013 |
Inhalable DNase I microparticles engineered with biologically active excipients.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Administration, Inhalation; Aerosols; Animals; Chitosan; Cystic Fibrosis; Delayed-Action Preparations; Deoxyribonuclease I; Dextrans; Drug Carriers; Drug Delivery Systems; Epithelial Cells; Excipients; Lactic Acid; Macrophages; Mice; Mucus; Ovalbumin; Polyglutamic Acid; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Powders; Viscosity | 2013 |
Preparation and drug release mechanism of CTS-TAX-NP-MSCs drug delivery system.
Topics: Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Cell Line, Tumor; Cell Movement; Chitosan; Drug Compounding; Drug Delivery Systems; Humans; Lactic Acid; Mesenchymal Stem Cells; Mice; Multidrug Resistance-Associated Proteins; Nanoparticles; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley | 2013 |
Biomedical applications of immobilized enzymes: an update.
Topics: Animals; Biocatalysis; Chitosan; Dipeptidases; Drug Compounding; Enzymes, Immobilized; Humans; Lactic Acid; Liposomes; Nanocapsules; Nanomedicine; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Superoxide Dismutase | 2013 |
N-lauroyl chitosan surface-modified PLGA nanoparticles as carrier for adriamycin to overcome cancer drug resistance.
Topics: Breast Neoplasms; Cell Line, Tumor; Chitosan; Doxorubicin; Drug Carriers; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Lactic Acid; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2014 |
Long-acting inhalable chitosan-coated poly(lactic-co-glycolic acid) nanoparticles containing hydrophobically modified exendin-4 for treating type 2 diabetes.
Topics: Administration, Inhalation; Adsorption; Analysis of Variance; Animals; Blood Glucose; Cell Line; Cell Survival; Chitosan; Diabetes Mellitus, Type 2; Drug Carriers; Exenatide; Humans; Hydrophobic and Hydrophilic Interactions; Lactic Acid; Male; Mice; Mice, Inbred C57BL; Nanoparticles; Peptides; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Surface Properties; Venoms | 2013 |
Formation and characterization of chitosan-polylacticacid-polyethylene glycol-gelatin nanoparticles: a novel biosystem for controlled drug delivery.
Topics: Chitosan; Delayed-Action Preparations; Drug Carriers; Gelatin; Lactic Acid; Mycobacterium smegmatis; Nanoparticles; Particle Size; Polyesters; Polyethylene Glycols; Polymers; Rifampin; Solvents; Volatilization | 2013 |
The properties of antimicrobial films derived from poly(lactic acid)/starch/chitosan blended matrix.
Topics: Anti-Infective Agents; Chitosan; Food Packaging; Hydrophobic and Hydrophilic Interactions; Lactic Acid; Polyesters; Polymers; Starch; Temperature; Tensile Strength | 2013 |
Coaxially electrospun core/shell structured poly(L-lactide) acid/chitosan nanofibers for potential drug carrier in tissue engineering.
Topics: Biocompatible Materials; Cell Survival; Chitosan; Electrochemistry; Feasibility Studies; Lactic Acid; Materials Testing; Nanocapsules; Particle Size; Polyesters; Polymers; Rotation | 2013 |
Poly(L-glutamic acid)/chitosan polyelectrolyte complex porous microspheres as cell microcarriers for cartilage regeneration.
Topics: Animals; Cartilage; Chitosan; Electrolytes; Fluorescence; Lactic Acid; Mice; Microscopy, Electron, Scanning; Microspheres; Polyglutamic Acid; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Porosity; Regeneration; Static Electricity; Tissue Scaffolds | 2014 |
Surface modification of PLLA nano-scaffolds with laminin multilayer by LbL assembly for enhancing neurite outgrowth.
Topics: Animals; Cell Differentiation; Cell Proliferation; Cell Survival; Cerebellum; Chitosan; Coated Materials, Biocompatible; Electrochemical Techniques; Embryo, Mammalian; Ganglia, Spinal; Lactic Acid; Laminin; Mice; Nanofibers; Neural Stem Cells; Neurites; Polyesters; Polymers; Rats; Rats, Sprague-Dawley; Static Electricity; Tissue Engineering; Tissue Scaffolds | 2013 |
Advanced cardiovascular stent coated with nanofiber.
Topics: Cell Proliferation; Cells, Cultured; Chemistry, Pharmaceutical; Chitosan; Coronary Restenosis; Drug Carriers; Drug-Eluting Stents; Estradiol; Humans; Hydrogen Peroxide; Lactic Acid; Nanofibers; Nanoparticles; Nitric Oxide; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Polymethacrylic Acids; Propanols; Reactive Oxygen Species | 2013 |
Enhanced anti-topoisomerase II activity by mucoadhesive 4-CBS-chitosan/poly (lactic acid) nanoparticles.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Chitosan; Delayed-Action Preparations; DNA Topoisomerases, Type II; Doxorubicin; Drug Carriers; Drug Compounding; Fibroblasts; Humans; Inhibitory Concentration 50; Lactic Acid; Microscopy, Electron, Scanning; Nanoparticles; Organ Specificity; Particle Size; Plasmids; Polyesters; Polymers; Sulfonamides | 2013 |
Brain pharmacokinetics of neurotoxin-loaded PLA nanoparticles modified with chitosan after intranasal administration in awake rats.
Topics: Administration, Intranasal; Analgesics, Non-Narcotic; Animals; Biological Availability; Blood-Brain Barrier; Chitosan; Cobra Neurotoxin Proteins; Drug Compounding; Drug Delivery Systems; Fluorescent Dyes; Half-Life; Lactic Acid; Male; Microdialysis; Nanoparticles; Neurons; Periaqueductal Gray; Polyesters; Polymers; Random Allocation; Rats; Rats, Sprague-Dawley; Surface Properties; Tissue Distribution | 2013 |
Adrenomedullin delivery in microsphere-scaffold composite for remodeling of the alveolar bone following tooth extraction: an experimental study in the rat.
Topics: Adrenomedullin; Animals; Biocompatible Materials; Bone Density; Bone Remodeling; Chitosan; Drug Carriers; Durapatite; Humans; Kinetics; Lactic Acid; Male; Microspheres; Nanostructures; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Wistar; Temperature; Tissue Scaffolds; Tooth Extraction | 2013 |
A predictive model for assessment of decontamination effects of lactic acid and chitosan used in combination on Vibrio parahaemolyticus in shrimps.
Topics: Animals; Chitosan; Colony Count, Microbial; Food Contamination; Food Microbiology; Food Quality; Lactic Acid; Models, Theoretical; Seafood; Shellfish; Vibrio parahaemolyticus | 2013 |
A sulfuric-lactic acid process for efficient purification of fungal chitosan with intact molecular weight.
Topics: Cell Wall; Chitosan; Glucosamine; Lactic Acid; Rhizopus; Sulfuric Acids | 2014 |
Impact of 3-D printed PLA- and chitosan-based scaffolds on human monocyte/macrophage responses: unraveling the effect of 3-D structures on inflammation.
Topics: Actins; Cell Shape; Cells, Cultured; Chitosan; Cytokines; Humans; Inflammation; Lactic Acid; Macrophages; Microscopy, Electron, Scanning; Monocytes; Polyesters; Polymers; Staining and Labeling; Tissue Scaffolds | 2014 |
Ultrasound-triggered regulation of blood glucose levels using injectable nano-network.
Topics: Alginates; Animals; Blood Glucose; Chitosan; Diabetes Mellitus, Experimental; Drug Carriers; Glucuronic Acid; Hexuronic Acids; Hypoglycemic Agents; Insulin; Lactic Acid; Male; Mice; Mice, Inbred C57BL; Nanostructures; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Ultrasonic Therapy | 2014 |
Development of chitosan and polylactic acid based methotrexate intravitreal micro-implants to treat primary intraocular lymphoma: an in vitro study.
Topics: Absorption, Physicochemical; Animals; Capsules; Chitosan; Diffusion; Drug Implants; Humans; In Vitro Techniques; Intraocular Lymphoma; Intravitreal Injections; Lactic Acid; Materials Testing; Methotrexate; Polyesters; Polymers; Treatment Outcome | 2014 |
Multimodal nanoparticles that provide immunomodulation and intracellular drug delivery for infectious diseases.
Topics: Chitosan; Cytokines; Drug Delivery Systems; Female; Humans; Immunologic Factors; Lactic Acid; Male; Monocytes; Mycobacterium tuberculosis; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Tuberculosis | 2014 |
Targeted oral delivery of BmpB vaccine using porous PLGA microparticles coated with M cell homing peptide-coupled chitosan.
Topics: Administration, Oral; Animals; Bacterial Outer Membrane Proteins; Bacterial Vaccines; Chitosan; Female; Lactic Acid; Lipoproteins; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred BALB C; Microscopy, Electron, Scanning; Microspheres; Peptides; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2014 |
Chitosan-zinc chelate improves intestinal structure and mucosal function and decreases apoptosis in ileal mucosal epithelial cells in weaned pigs.
Topics: Amine Oxidase (Copper-Containing); Animals; Apoptosis; Biological Availability; Chelating Agents; Chitosan; Diet; Dietary Supplements; Endotoxins; Epithelial Cells; Ileum; Immunoglobulin A, Secretory; In Situ Nick-End Labeling; Intestinal Mucosa; Intestine, Small; Lactic Acid; Male; Mucus; Swine; Weaning; Zinc | 2014 |
Nose-to-brain delivery: evaluation of polymeric nanoparticles on olfactory ensheathing cells uptake.
Topics: Administration, Intranasal; Animals; Blood-Brain Barrier; Brain; Chemistry, Pharmaceutical; Chitosan; Drug Delivery Systems; Fluorescent Dyes; Lactic Acid; Microscopy, Confocal; Microscopy, Electron, Scanning; Molecular Weight; Nanoparticles; Nasal Mucosa; Olfactory Mucosa; Particle Size; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rats; Rhodamines; Suspensions | 2014 |
Inhalable microspheres embedding chitosan-coated PLGA nanoparticles for 2-methoxyestradiol.
Topics: 2-Methoxyestradiol; Administration, Inhalation; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Chitosan; Drug Carriers; Drug Compounding; Drug Liberation; Estradiol; Humans; Lactic Acid; Lung; Microspheres; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Surface Properties; Tissue Distribution | 2014 |
[Preparation of microspheres of superoxide dismutase and their activities].
Topics: Alginates; Chitosan; Delayed-Action Preparations; Glucuronic Acid; Hexuronic Acids; Lactic Acid; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Superoxide Dismutase | 2013 |
Quantification of nanoparticle uptake into hair follicles in pig ear and human forearm.
Topics: Administration, Cutaneous; Animals; Chitosan; Drug Carriers; Ear; Female; Fluorescent Dyes; Forearm; Hair Follicle; Humans; Lactic Acid; Male; Nanoparticles; Particle Size; Phospholipids; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Skin Absorption; Surface Properties; Swine | 2014 |
Hierarchical structure and physicochemical properties of plasticized chitosan.
Topics: Calorimetry, Differential Scanning; Chitosan; Glycerol; Lactic Acid; Microscopy, Electron, Scanning; Plasticizers; Spectroscopy, Fourier Transform Infrared; Water; X-Ray Diffraction | 2014 |
Role of HGF-loaded nanoparticles in treating rat acute hepatic failure.
Topics: Animals; Biomarkers; Cells, Cultured; Chemistry, Pharmaceutical; Chitosan; Delayed-Action Preparations; Disease Models, Animal; Drug Carriers; Female; Hepatocyte Growth Factor; Hepatocytes; Injections, Intraperitoneal; Injections, Intravenous; Ki-67 Antigen; Lactic Acid; Liver Failure, Acute; Liver Regeneration; Male; Mitotic Index; Nanoparticles; Polyesters; Polymers; Rats; Rats, Sprague-Dawley; Time Factors | 2013 |
[Transport of PLGA nanoparticles across Caco-2/HT29-MTX co-cultured cells].
Topics: Biological Transport; Caco-2 Cells; Chitosan; Coated Materials, Biocompatible; Coculture Techniques; Drug Carriers; Furans; Heterocyclic Compounds, 2-Ring; HT29 Cells; Humans; Lactic Acid; Nanoparticles; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Zonula Occludens-1 Protein | 2013 |
Construction and evaluation of Fe₃O₄-based PLGA nanoparticles carrying rtPA used in the detection of thrombosis and in targeted thrombolysis.
Topics: Animals; Chitosan; Drug Carriers; Drug Delivery Systems; Fibrinolytic Agents; Humans; Lactic Acid; Magnetic Resonance Imaging; Magnetite Nanoparticles; Peptides, Cyclic; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Thrombosis; Tissue Plasminogen Activator | 2014 |
An amperometric uric acid biosensor based on chitosan-carbon nanotubes electrospun nanofiber on silver nanoparticles.
Topics: Ascorbic Acid; Biosensing Techniques; Buffers; Catalysis; Chitosan; Electrochemistry; Electrodes; Enzymes, Immobilized; Glucose; Hydrogen-Ion Concentration; Lactic Acid; Limit of Detection; Metal Nanoparticles; Nanofibers; Nanotubes, Carbon; Oxygen; Silver; Urate Oxidase; Uric Acid; Urine | 2014 |
Enhanced humoral and cell-mediated immune responses generated by cationic polymer-coated PLA microspheres with adsorbed HBsAg.
Topics: Adsorption; Animals; Cations; Chemistry, Pharmaceutical; Chitosan; Drug Delivery Systems; Female; Hepatitis B Surface Antigens; Immunity, Cellular; Immunity, Humoral; Interleukins; Lactic Acid; Mice; Mice, Inbred BALB C; Microspheres; Polyesters; Polyethyleneimine; Polymers; Tumor Necrosis Factor-alpha | 2014 |
Bi-layer scaffold of chitosan/PCL-nanofibrous mat and PLLA-microporous disc for skin tissue engineering.
Topics: Bandages; Cell Proliferation; Cell Survival; Cells, Cultured; Chitosan; Equipment Design; Equipment Failure Analysis; Humans; Lactic Acid; Materials Testing; Nanofibers; Particle Size; Polyesters; Polymers; Porosity; Skin; Skin, Artificial; Surface Properties; Tissue Engineering; Tissue Scaffolds | 2014 |
Chitosan-coated electrospun PLA fibers for rapid mineralization of calcium phosphate.
Topics: Alkaline Phosphatase; Calcium Phosphates; Cell Adhesion; Cell Line; Cell Proliferation; Chitosan; Coated Materials, Biocompatible; Crystallization; Durapatite; Enzyme Assays; Humans; Lactic Acid; Minerals; Nanofibers; Osteoblasts; Polyesters; Polymers; Spectrometry, X-Ray Emission; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Tissue Engineering; X-Ray Diffraction | 2014 |
Poly(lactic acid) nanoparticles coated with combined WGA and water-soluble chitosan for mucosal delivery of β-galactosidase.
Topics: Administration, Oral; Adsorption; Animals; beta-Galactosidase; Chitosan; Drug Carriers; Drug Delivery Systems; Drug Stability; Excipients; Half-Life; Intestinal Mucosa; Intestine, Small; Lactic Acid; Nanoparticles; Particle Size; Polyesters; Polymers; Rats; Rats, Wistar; Suspensions; Water; Wheat Germ Agglutinins | 2014 |
Improved antitumor activity and reduced cardiotoxicity of epirubicin using hepatocyte-targeted nanoparticles combined with tocotrienols against hepatocellular carcinoma in mice.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cardiotoxicity; Cell Survival; Chitosan; Disease Models, Animal; Drug Delivery Systems; Epirubicin; Glutathione; Heart; Hep G2 Cells; Hepatocytes; Humans; Lactic Acid; Lipid Peroxidation; Liver; Liver Neoplasms; Mice; Nanoparticles; Neovascularization, Pathologic; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Superoxide Dismutase; Tocotrienols; Tumor Suppressor Protein p53 | 2014 |
Biodegradable polyester-based microcarriers with modified surface tailored for tissue engineering.
Topics: Animals; Biocompatible Materials; Cell Adhesion; Cell Line; Cell Proliferation; Cell Survival; Chitosan; Emulsions; Fibroblasts; Lactic Acid; Materials Testing; Methacrylates; Mice; Microscopy, Electron, Scanning; Microspheres; Nylons; Polyesters; Polymers; Solubility; Spectrum Analysis, Raman; Surface Properties; Tissue Engineering | 2015 |
PLA/chitosan/keratin composites for biomedical applications.
Topics: Biocompatible Materials; Cell Line; Cell Survival; Chitosan; Elastic Modulus; Hardness; Humans; Keratins; Lactic Acid; Polyesters; Polymers; Surface Properties; Tensile Strength | 2014 |
Preparation and in vitro evaluation of thienorphine-loaded PLGA nanoparticles.
Topics: Administration, Oral; Animals; Biological Availability; Buprenorphine; Caco-2 Cells; Chemistry, Pharmaceutical; Chitosan; Drug Carriers; Drug Delivery Systems; Excipients; Humans; Lactic Acid; Male; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Wistar | 2016 |
Influence of the acid type in the production of chitosan films reinforced with bacterial nanocellulose.
Topics: Acetic Acid; Cellulose; Chitosan; Food Packaging; Gluconacetobacter; Lactic Acid; Nanostructures | 2014 |
Physicochemical features and transfection properties of chitosan/poloxamer 188/poly(D,L-lactide-co-glycolide) nanoplexes.
Topics: Chitosan; DNA; Emulsions; HeLa Cells; Humans; Lactic Acid; Nanocapsules; Nanocomposites; Poloxamer; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Transfection | 2014 |
Chitosan coated polylactic acid nanoparticle-mediated combinatorial delivery of cisplatin and siRNA/Plasmid DNA chemosensitizes cisplatin-resistant human ovarian cancer cells.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Chitosan; Cisplatin; Drug Delivery Systems; Drug Resistance, Neoplasm; Female; Fluorescamine; Humans; Inhibitory Concentration 50; Lactic Acid; Nanomedicine; Nanoparticles; Ovarian Neoplasms; Particle Size; Plasmids; Polyesters; Polymers; Proteasome Endopeptidase Complex; RNA-Binding Proteins; RNA, Small Interfering | 2014 |
Synthesis and characterization of poly(lactic-co-glycolic) acid nanoparticles-loaded chitosan/bioactive glass scaffolds as a localized delivery system in the bone defects.
Topics: Animals; Bone and Bones; Chitosan; Glass; Humans; Lactic Acid; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Tissue Engineering; Tissue Scaffolds | 2014 |
Simple control of surface topography of gold nanoshells by a surfactant-less seeded-growth method.
Topics: Chitosan; Gold; Lactic Acid; Nanoshells; Particle Size; Poloxamer; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Surface Properties | 2014 |
Double-effective chitosan scaffold-PLGA nanoparticle system for brain tumour therapy: in vitro study.
Topics: Antimetabolites, Antineoplastic; Brain Neoplasms; Cell Line, Tumor; Chitosan; Drug Carriers; Fluorouracil; Glioblastoma; Human Umbilical Vein Endothelial Cells; Humans; Lactic Acid; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2014 |
Development and characterization of GRGDSPC-modified poly(lactide-co-glycolide acid) porous microspheres incorporated with protein-loaded chitosan microspheres for bone tissue engineering.
Topics: Bone Development; Cell Adhesion; Chitosan; Humans; Lactic Acid; Microscopy, Electron, Scanning; Microspheres; Oligopeptides; Osteoblasts; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Porosity; Proteins; Thermogravimetry; Tissue Engineering | 2014 |
Enhanced osteogenesis of bone morphology protein-2 in 2-N,6-O-sulfated chitosan immobilized PLGA scaffolds.
Topics: Animals; Bone Morphogenetic Protein 2; Cell Adhesion; Cell Line; Chitosan; Lactic Acid; Mice; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Osteogenesis; Photoelectron Spectroscopy; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Recombinant Proteins; Static Electricity | 2014 |
Amphiphilic chitosan-grafted-functionalized polylactic acid based nanoparticles as a delivery system for doxorubicin and temozolomide co-therapy.
Topics: Chitosan; Dacarbazine; Doxorubicin; Drug Delivery Systems; Humans; Lactic Acid; Male; Molecular Structure; Nanoparticles; Particle Size; Polyesters; Polymers; Surface Properties; Surface-Active Agents; Temozolomide; Temperature | 2014 |
Efficient nanoparticle-mediated needle-free transcutaneous vaccination via hair follicles requires adjuvantation.
Topics: Adjuvants, Immunologic; Administration, Cutaneous; Animals; Antigens; Cell Proliferation; Chitosan; Cytokines; Drug Carriers; Female; Immunity, Humoral; Lactic Acid; Mice; Mice, Inbred C57BL; Nanomedicine; Nanoparticles; Needles; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; T-Lymphocytes; Vaccination | 2015 |
Effect of chitosan concentration on PLGA microcapsules for controlled release and stability of resveratrol.
Topics: Capsules; Chitosan; Delayed-Action Preparations; Drug Delivery Systems; Humans; Lactic Acid; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Resveratrol; Stilbenes | 2015 |
Characterization of a co-electrospun scaffold of HLC/CS/PLA for vascular tissue engineering.
Topics: Biomimetic Materials; Blood Vessels; Chitosan; Collagen Type I; Electroplating; Equipment Failure Analysis; Extracellular Matrix; Feasibility Studies; Humans; Lactic Acid; Materials Testing; Polyesters; Polymers; Prosthesis Design; Tissue Engineering; Tissue Scaffolds; Vascular Grafting | 2014 |
Engineering of Δ9-tetrahydrocannabinol delivery systems based on surface modified-PLGA nanoplatforms.
Topics: Chitosan; Dronabinol; Drug Carriers; Lactic Acid; Nanoparticles; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2014 |
Potential avoidance of adverse analgesic effects using a biologically "smart" hydrogel capable of controlled bupivacaine release.
Topics: Anesthetics, Local; Animals; Bupivacaine; Cell Line; Chemistry, Pharmaceutical; Chitosan; Delayed-Action Preparations; Drug Carriers; Hydrogels; Hydrogen-Ion Concentration; Inflammation Mediators; Kinetics; Lactic Acid; Macrophages; Mice; Particle Size; Phagocytosis; Poloxamer; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solubility; Technology, Pharmaceutical | 2014 |
Poly (lactic acid)/chitosan fiber mats: investigation of effects of the support on lipase immobilization.
Topics: Chitosan; Enzymes, Immobilized; Lactic Acid; Lipase; Nanofibers; Polyesters; Polymers; Surface Properties; Tensile Strength; Tissue Engineering | 2015 |
Effect of the physicochemical properties of pure or chitosan-coated poly(L-lactic acid)scaffolds on the chondrogenic differentiation of mesenchymal stem cells from osteoarthritic patients.
Topics: Adsorption; Cell Differentiation; Cell Proliferation; Cell Survival; Cellular Microenvironment; Chitosan; Chondrocytes; Chondrogenesis; Coated Materials, Biocompatible; Humans; Lactic Acid; Mesenchymal Stem Cells; Osteoarthritis; Polyesters; Polymers; Tissue Scaffolds | 2015 |
Toxic effects of aflatoxin B1 on embryonic development of zebrafish (Danio rerio): potential activity of piceatannol encapsulated chitosan/poly (lactic acid) nanoparticles.
Topics: Aflatoxin B1; Animals; Chitosan; Drug Carriers; Embryonic Development; Heart Rate; Lactic Acid; Nanoparticles; Particle Size; Polyesters; Polymers; Stilbenes; Zebrafish | 2015 |
Chitosan-coated poly(lactic-co-glycolic) acid nanoparticles as an efficient delivery system for Newcastle disease virus DNA vaccine.
Topics: Animals; Chickens; Chitosan; DNA, Viral; Drug Carriers; Immunoglobulin A; Lactic Acid; Lymphocytes; Nanoparticles; Newcastle Disease; Newcastle disease virus; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Tears; Vaccines, DNA | 2014 |
Chitosan-poly (lactide-co-glycolide) (CS-PLGA) nanoparticles containing metformin HCl: preparation and in vitro evaluation.
Topics: Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Chitosan; Lactic Acid; Metformin; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solubility; Spectroscopy, Fourier Transform Infrared | 2014 |
Evaluation of polymeric nanoparticle formulations by effective imaging and quantitation of cellular uptake for controlled delivery of doxorubicin.
Topics: 3T3 Cells; Animals; Cell Line; Cell Line, Tumor; Chitosan; Doxorubicin; Drug Carriers; Drug Delivery Systems; Humans; Hydrophobic and Hydrophilic Interactions; Lactic Acid; Magnetics; Mice; Microscopy, Confocal; Microscopy, Electron, Scanning; Microspheres; Nanoparticles; Nanotechnology; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Quantum Dots; Rats; Solubility; Surface Properties; Theranostic Nanomedicine; Water | 2015 |
Ferulic acid-coupled chitosan: thermal stability and utilization as an antioxidant for biodegradable active packaging film.
Topics: Antioxidants; Biphenyl Compounds; Chitosan; Coumaric Acids; Food Packaging; Glycerol; Hot Temperature; Lactic Acid; Oxygen; Picrates; Polyesters; Polymers; Starch; Tensile Strength; Water; X-Ray Diffraction | 2015 |
Surface coating mediates the toxicity of polymeric nanoparticles towards human-like macrophages.
Topics: Cell Survival; Chitosan; Excipients; Humans; Lactic Acid; Macrophages; Nanoparticles; Poloxamer; Polyglycolic Acid; Polyvinyl Alcohol | 2015 |
Biodistribution of PLGA and PLGA/chitosan nanoparticles after repeat-dose oral delivery in F344 rats for 7 days.
Topics: Administration, Oral; Animals; Chemistry, Pharmaceutical; Chitosan; Drug Administration Schedule; Drug Carriers; Fluorescent Dyes; Intestinal Absorption; Lactic Acid; Male; Nanotechnology; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats, Inbred F344; Rhodamines; Surface Properties; Technology, Pharmaceutical; Tissue Distribution | 2014 |
Poly(lactic acid)/chitosan hybrid nanoparticles for controlled release of anticancer drug.
Topics: Antineoplastic Agents; Chitosan; Delayed-Action Preparations; Lactic Acid; Microscopy, Electron, Scanning; Nanoparticles; Polyesters; Polymers | 2015 |
Induction of mucosal immune responses and protection of cattle against direct-contact challenge by intranasal delivery with foot-and-mouth disease virus antigen mediated by nanoparticles.
Topics: Administration, Intranasal; Animals; Antibodies, Viral; Antigens, Viral; Cattle; Cell Proliferation; Chitosan; Foot-and-Mouth Disease; Foot-and-Mouth Disease Virus; Immunity, Mucosal; Immunoglobulin G; Lactic Acid; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; T-Lymphocytes; Trehalose; Viral Vaccines | 2014 |
Comparison of sorafenib-loaded poly (lactic/glycolic) acid and DPPC liposome nanoparticles in the in vitro treatment of renal cell carcinoma.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Antineoplastic Agents; Carcinoma, Renal Cell; Cell Line, Tumor; Chemistry, Pharmaceutical; Chitosan; Dose-Response Relationship, Drug; Drug Carriers; Humans; Hydrophobic and Hydrophilic Interactions; Kidney Neoplasms; Kinetics; Lactic Acid; Liposomes; Nanoparticles; Nanotechnology; Niacinamide; Phenylurea Compounds; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solubility; Sorafenib; Technology, Pharmaceutical | 2015 |
Nanobiocomposite of poly(lactide-co-glycolide)/chitosan electrospun scaffold can promote proliferation and transdifferentiation of Schwann-like cells from human adipose-derived stem cells.
Topics: Adipose Tissue; Biocompatible Materials; Cell Differentiation; Cell Proliferation; Chitosan; Humans; Lactic Acid; Nanocomposites; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Schwann Cells; Stem Cells | 2015 |
Cellular uptake, antioxidant and antiproliferative activity of entrapped α-tocopherol and γ-tocotrienol in poly (lactic-co-glycolic) acid (PLGA) and chitosan covered PLGA nanoparticles (PLGA-Chi).
Topics: alpha-Tocopherol; Antineoplastic Agents; Antioxidants; Caco-2 Cells; Cell Line, Tumor; Cell Proliferation; Chitosan; Chromans; Humans; Lactic Acid; Nanoparticles; Neoplasms; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Vitamin E | 2015 |
Nanoparticle diffusion within intestinal mucus: Three-dimensional response analysis dissecting the impact of particle surface charge, size and heterogeneity across polyelectrolyte, pegylated and viral particles.
Topics: Acrylic Resins; Animals; Biological Transport; Chitosan; Diffusion; Electrolytes; Jejunum; Lactic Acid; Microscopy, Atomic Force; Mucus; Nanoparticles; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rheology; Surface Properties; Swine; Virion | 2015 |
Knockdown of STAT3 expression in SKOV3 cells by biodegradable siRNA-PLGA/CSO conjugate micelles.
Topics: Apoptosis; Biocompatible Materials; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chitosan; Gene Knockdown Techniques; Humans; Lactic Acid; Micelles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Proton Magnetic Resonance Spectroscopy; Real-Time Polymerase Chain Reaction; RNA, Small Interfering; STAT3 Transcription Factor; Static Electricity; Transfection | 2015 |
Evaluation of nanoformulated therapeutics in an ex-vivo bovine corneal irritation model.
Topics: Animals; Burns, Chemical; Cattle; Chitosan; Cornea; Eye Burns; Inhibitor of Apoptosis Proteins; Lactic Acid; Lactoferrin; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Sodium Hydroxide | 2015 |
Patterned substrates fabricated by a controlled freezing approach and biocompatibility evaluation by stem cells.
Topics: Biocompatible Materials; Chitosan; Freezing; Lactic Acid; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Spectroscopy, Fourier Transform Infrared; Stem Cells | 2015 |
Inverse micellar sugar glass (IMSG) nanoparticles for transfollicular vaccination.
Topics: Adjuvants, Immunologic; Administration, Intranasal; Animals; Antigens; Carbohydrates; Chitosan; Drug Carriers; Female; Hair Follicle; Immunity, Cellular; Immunity, Humoral; Injections, Intradermal; Lactic Acid; Mice, Inbred C57BL; Micelles; Nanoparticles; Ovalbumin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Vaccination | 2015 |
Biodegradable chitosan and polylactic acid-based intraocular micro-implant for sustained release of methotrexate into vitreous: analysis of pharmacokinetics and toxicity in rabbit eyes.
Topics: Absorbable Implants; Animals; Antimetabolites, Antineoplastic; Biocompatible Materials; Chitosan; Drug Delivery Systems; Drug Implants; Intravitreal Injections; Lactic Acid; Methotrexate; Models, Animal; Polyesters; Polymers; Rabbits; Retina; Vitreous Body | 2015 |
In vitro and in vivo evaluation of Δ⁹-tetrahidrocannabinol/PLGA nanoparticles for cancer chemotherapy.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Cell Survival; Chemistry, Pharmaceutical; Chitosan; Dronabinol; Drug Compounding; Drug Screening Assays, Antitumor; Humans; Lactic Acid; Materials Testing; Mice; Mice, Inbred C57BL; Nanoparticles; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Xenograft Model Antitumor Assays | 2015 |
Enhancement of VEGF-Mediated Angiogenesis by 2-N,6-O-Sulfated Chitosan-Coated Hierarchical PLGA Scaffolds.
Topics: Capillaries; Cell Adhesion; Cell Proliferation; Cell Shape; Cell Survival; Chitosan; Coated Materials, Biocompatible; Human Umbilical Vein Endothelial Cells; Humans; Intracellular Space; Lactic Acid; Microspheres; Neovascularization, Physiologic; Nitric Oxide; Photoelectron Spectroscopy; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Porosity; Protein Binding; Tissue Scaffolds; Vascular Endothelial Growth Factor A | 2015 |
Poly(d,l-lactide-co-glycolide)-chitosan composite particles for the treatment of lung cancer.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Chitosan; Drug Carriers; Drug Synergism; Humans; Lactic Acid; Lung Neoplasms; Nanocomposites; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Topotecan | 2015 |
Cytotoxicity and intracellular fate of PLGA and chitosan-coated PLGA nanoparticles in Madin-Darby bovine kidney (MDBK) and human colorectal adenocarcinoma (Colo 205) cells.
Topics: Animals; Cattle; Cell Death; Cell Line, Tumor; Chitosan; Endocytosis; Flow Cytometry; Humans; Intracellular Space; Kinetics; Lactic Acid; Microscopy, Fluorescence; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Static Electricity; Surface-Active Agents | 2015 |
N-trimethyl chitosan chloride-coated PLGA nanoparticles overcoming multiple barriers to oral insulin absorption.
Topics: Administration, Oral; Animals; Chitosan; Diabetes Mellitus, Experimental; Drug Carriers; Drug Delivery Systems; Humans; Insulin; Lactic Acid; Male; Mice; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Wistar | 2015 |
Effect of molecular weight reduction by gamma irradiation on chitosan film properties.
Topics: Chitosan; Food Packaging; Gamma Rays; Lactic Acid; Molecular Weight; Permeability; Polysorbates; Solubility; Steam; Tensile Strength | 2015 |
Repair of rat cranial bone defect by using bone morphogenetic protein-2-related peptide combined with microspheres composed of polylactic acid/polyglycolic acid copolymer and chitosan.
Topics: Animals; Bone Morphogenetic Protein 2; Bone Substitutes; Capsules; Chitosan; Delayed-Action Preparations; Fracture Healing; Lactic Acid; Polyesters; Polyglycolic Acid; Polymers; Rats; Rats, Sprague-Dawley; Skull Fractures; Treatment Outcome | 2015 |
Nimesulide-loaded nanoparticles for the potential coadjuvant treatment of prostate cancer.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Calorimetry, Differential Scanning; Cell Line, Tumor; Cell Survival; Chitosan; Drug Carriers; Drug Liberation; Humans; Lactic Acid; Male; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Prostatic Neoplasms; Spectroscopy, Fourier Transform Infrared; Sulfonamides | 2015 |
Chitooligosaccharides as novel ingredients of fermented foods.
Topics: Animals; Bioreactors; Chitin; Chitosan; Decapoda; Dietary Supplements; Digestion; Fatty Acids; Hydrolysis; Lactic Acid; Lactobacillaceae; Linoleic Acids, Conjugated; Lipid Metabolism; Nutritive Value; Oligosaccharides; Yogurt | 2015 |
Influence of Parathyroid Hormone-Loaded PLGA Nanoparticles in Porous Scaffolds for Bone Regeneration.
Topics: Bone Regeneration; Calcification, Physiologic; Cell Survival; Chitosan; Drug Liberation; Gelatin; Humans; Lactic Acid; Nanoparticles; Osteoblasts; Parathyroid Hormone; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Porosity; Tissue Scaffolds | 2015 |
Hyaluronic acid-decorated dual responsive nanoparticles of Pluronic F127, PLGA, and chitosan for targeted co-delivery of doxorubicin and irinotecan to eliminate cancer stem-like cells.
Topics: Animals; Antineoplastic Agents; Camptothecin; Cell Line, Tumor; Chitosan; Doxorubicin; Drug Delivery Systems; Drug Liberation; Drug Resistance, Neoplasm; Endocytosis; Humans; Hyaluronic Acid; Hydrogen-Ion Concentration; Intracellular Space; Irinotecan; Lactic Acid; Male; Mice, Nude; Nanoparticles; Neoplastic Stem Cells; Poloxamer; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Spheroids, Cellular; Tissue Distribution | 2015 |
Engineering vascularized soft tissue flaps in an animal model using human adipose-derived stem cells and VEGF+PLGA/PEG microspheres on a collagen-chitosan scaffold with a flow-through vascular pedicle.
Topics: Adipocytes; Animals; Aorta; Cell Proliferation; Cell Survival; Chitosan; Collagen; Culture Media, Conditioned; Female; Green Fluorescent Proteins; Humans; Immunohistochemistry; Lactic Acid; Macrophages; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Microspheres; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Nude; Silicones; Stem Cells; Surgical Flaps; Tissue Engineering; Tissue Scaffolds; Vascular Endothelial Growth Factor A | 2015 |
Chitosan grafted low molecular weight polylactic acid for protein encapsulation and burst effect reduction.
Topics: Chitosan; Delayed-Action Preparations; Hydrogen-Ion Concentration; Lactic Acid; Molecular Weight; Nanoparticles; Polyesters; Polymers; Serum Albumin, Bovine; Solubility; Spectroscopy, Fourier Transform Infrared | 2015 |
Preferential tumor accumulation and desirable interstitial penetration of poly(lactic-co-glycolic acid) nanoparticles with dual coating of chitosan oligosaccharide and polyethylene glycol-poly(D,L-lactic acid).
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Chitosan; Female; Humans; Lactic Acid; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Oligosaccharides; Polyesters; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Xenograft Model Antitumor Assays | 2016 |
Microspheres prepared with different co-polymers of poly(lactic-glycolic acid) (PLGA) or with chitosan cause distinct effects on macrophages.
Topics: Chitosan; Lactic Acid; Macrophages; Microscopy, Electron, Scanning; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers | 2015 |
[Preparation and evaluation of risperidone-loaded microsphere/sucrose acetate isobutyrate in situ forming complex depot with double diffusion barriers].
Topics: Chitosan; Drug Carriers; Lactic Acid; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Risperidone; Sucrose; Technology, Pharmaceutical | 2015 |
Assessment of the enhancement of PLGA nanoparticle uptake by dendritic cells through the addition of natural receptor ligands and monoclonal antibody.
Topics: Animals; Antibodies, Monoclonal; Antigens, CD; Cattle; Cells, Cultured; Chitosan; Dendritic Cells; Humans; Lactic Acid; Lectins, C-Type; Ligands; Mannans; Minor Histocompatibility Antigens; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Receptors, Cell Surface; Vaccines | 2015 |
Co-Delivery of Atorvastatin Nanocrystals in PLGA based in situ Gel for Anti-Hyperlipidemic Efficacy.
Topics: Anticholesteremic Agents; Atorvastatin; Chemistry, Pharmaceutical; Chitosan; Drug Carriers; Drug Liberation; Gels; Hyperlipidemias; Lactic Acid; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solvents; Surface Properties; X-Ray Diffraction | 2016 |
Bone regeneration by nanohydroxyapatite/chitosan/poly(lactide-co-glycolide) scaffolds seeded with human umbilical cord mesenchymal stem cells in the calvarial defects of the nude mice.
Topics: Animals; Bone Regeneration; Chitosan; Cord Blood Stem Cell Transplantation; Durapatite; Equipment Failure Analysis; Humans; Lactic Acid; Male; Mesenchymal Stem Cell Transplantation; Mice; Mice, Nude; Nanocomposites; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Prosthesis Design; Skull Fractures; Tissue Scaffolds; Treatment Outcome | 2015 |
Chitosan-coated poly(lactic-co-glycolic acid) perfluorooctyl bromide nanoparticles for cell labeling in (19)F magnetic resonance imaging.
Topics: Animals; Cell Line; Chitosan; Fluorine-19 Magnetic Resonance Imaging; Fluorocarbons; Humans; Hydrocarbons, Brominated; Lactic Acid; Macrophages; Mesenchymal Stem Cells; Mice; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2016 |
Composite chitosan/alginate hydrogel for controlled release of deferoxamine: A system to potentially treat iron dysregulation diseases.
Topics: Alginates; Chemistry, Pharmaceutical; Chitosan; Deferoxamine; Delayed-Action Preparations; Drug Carriers; Drug Liberation; Glucuronic Acid; Hexuronic Acids; Hydrogels; Iron; Lactic Acid; Metabolic Diseases; Microspheres; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Porosity; Viscosity | 2016 |
Compared in vivo toxicity in mice of lung delivered biodegradable and non-biodegradable nanoparticles.
Topics: Administration, Inhalation; Aerosols; Animals; Bronchoalveolar Lavage; Chitosan; Inflammation Mediators; Lactic Acid; Lung; Mice; Nanoparticles; Poloxamer; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polystyrenes; Polyvinyl Alcohol; Tissue Distribution; Titanium | 2016 |
Electrochemical lactate biosensor based upon chitosan/carbon nanotubes modified screen-printed graphite electrodes for the determination of lactate in embryonic cell cultures.
Topics: Biosensing Techniques; Cells, Cultured; Chitosan; Conductometry; Electric Conductivity; Embryonic Stem Cells; Enzymes, Immobilized; Equipment Design; Equipment Failure Analysis; Graphite; Humans; Lactic Acid; Mixed Function Oxygenases; Nanotubes, Carbon; Photography | 2016 |
Delivery of miR-34a by chitosan/PLGA nanoplexes for the anticancer treatment of multiple myeloma.
Topics: Animals; Antineoplastic Agents; Chitosan; Drug Carriers; Humans; Lactic Acid; Mice; Mice, Inbred NOD; Mice, SCID; MicroRNAs; Multiple Myeloma; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Xenograft Model Antitumor Assays | 2015 |
Surface modification of PLGA nanoparticles with biotinylated chitosan for the sustained in vitro release and the enhanced cytotoxicity of epirubicin.
Topics: Animals; Antibiotics, Antineoplastic; Biotinylation; Breast Neoplasms; Carbocyanines; Cell Survival; Chitosan; Endocytosis; Epirubicin; Humans; Kinetics; Lactic Acid; MCF-7 Cells; Mice, Nude; Microscopy, Confocal; Microscopy, Electron, Scanning; Nanoparticles; Particle Size; Photoelectron Spectroscopy; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Surface Properties; Xenograft Model Antitumor Assays | 2016 |
Release behavior of tetracycline hydrochloride loaded chitosan/poly(lactic acid) antimicrobial nanofibrous membranes.
Topics: Chitosan; Delayed-Action Preparations; Lactic Acid; Membranes, Artificial; Nanofibers; Polyesters; Polymers; Staphylococcus aureus; Tetracycline | 2016 |
Synthesis of doxorubicin-PLGA loaded chitosan stabilized (Mn, Zn)Fe2O4 nanoparticles: Biological activity and pH-responsive drug release.
Topics: Chitosan; Delayed-Action Preparations; Doxorubicin; Ferrosoferric Oxide; HeLa Cells; Humans; Hydrogen-Ion Concentration; Lactic Acid; Manganese; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Zinc | 2016 |
PLGA/DPPC/trimethylchitosan spray-dried microparticles for the nasal delivery of ropinirole hydrochloride: in vitro, ex vivo and cytocompatibility assessment.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Administration, Intranasal; Animals; Antiparkinson Agents; Cell Line; Cell Survival; Chitosan; Drug Carriers; Humans; Indoles; Lactic Acid; Nasal Mucosa; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Sheep | 2016 |
Thermodynamic Insights and Conceptual Design of Skin-Sensitive Chitosan Coated Ceramide/PLGA Nanodrug for Regeneration of Stratum Corneum on Atopic Dermatitis.
Topics: Animals; Animals, Newborn; Cell Survival; Cells, Cultured; Ceramides; Chemokine CCL2; Chitosan; Dermatitis, Atopic; Dermatologic Agents; Drug Design; Fibroblasts; Gene Expression; Immunohistochemistry; Lactic Acid; Microscopy, Electron; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats, Sprague-Dawley; Regeneration; Reverse Transcriptase Polymerase Chain Reaction; Skin Absorption; Thermodynamics; Tumor Necrosis Factor-alpha | 2015 |
Polyurethane membrane/knitted mesh-reinforced collagen-chitosan bilayer dermal substitute for the repair of full-thickness skin defects via a two-step procedure.
Topics: Animals; Biocompatible Materials; Biomechanical Phenomena; Cattle; Chitosan; Collagen; Lactic Acid; Male; Membranes, Artificial; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polyurethanes; Rats; Rats, Sprague-Dawley; Skin; Skin, Artificial; Tissue Engineering | 2016 |
Chitosan-PLGA polymer blends as coatings for hydroxyapatite nanoparticles and their effect on antimicrobial properties, osteoconductivity and regeneration of osseous tissues.
Topics: Animals; Anti-Infective Agents; Biocompatible Materials; Bone Regeneration; Cell Line; Chitosan; Durapatite; Lactic Acid; Microbial Sensitivity Tests; Microscopy, Electron, Scanning; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers | 2016 |
Nanoparticle transport across in vitro olfactory cell monolayers.
Topics: Administration, Intranasal; Animals; Biological Transport; Blood-Brain Barrier; Brain; Cell-Penetrating Peptides; Chemistry, Pharmaceutical; Chitosan; Drug Delivery Systems; Female; Lactic Acid; Lipids; Nanoparticles; Nasal Mucosa; Olfactory Mucosa; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rats; Rats, Wistar | 2016 |
Downregulation of CD73 in 4T1 breast cancer cells through siRNA-loaded chitosan-lactate nanoparticles.
Topics: 5'-Nucleotidase; Animals; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Chitosan; Down-Regulation; Female; Flow Cytometry; Gene Expression; Lactic Acid; Mice; Nanoparticles; Real-Time Polymerase Chain Reaction; RNA, Small Interfering | 2016 |
Controlled-release of tetracycline and lovastatin by poly(D,L-lactide-co-glycolide acid)-chitosan nanoparticles enhances periodontal regeneration in dogs.
Topics: Alkaline Phosphatase; Animals; Anti-Bacterial Agents; Bacteria; Bone Regeneration; Chitosan; Delayed-Action Preparations; Dogs; Drug Carriers; Lactic Acid; Lovastatin; Male; Microscopy, Electron, Transmission; Nanoparticles; Osteoblasts; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Tetracycline | 2016 |
Treatment of bleomycin-induced pulmonary fibrosis by inhaled tacrolimus-loaded chitosan-coated poly(lactic-co-glycolic acid) nanoparticles.
Topics: Administration, Inhalation; Aerosols; Animals; Bleomycin; Chitosan; Collagen; Hydroxyproline; Imaging, Three-Dimensional; Lactic Acid; Lung; Male; Mice, Inbred C57BL; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Pulmonary Fibrosis; Static Electricity; Surface Properties; Tacrolimus; X-Ray Diffraction | 2016 |
Bioactive PLGA-curcumin microparticle-embedded chitosan scaffold: in vitro and in vivo evaluation.
Topics: Animals; Chitosan; Chlorocebus aethiops; Curcumin; Lactic Acid; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Staphylococcus aureus; Tissue Scaffolds; Vero Cells; Wound Healing | 2017 |
A blue fluorescent labeling technique utilizing micro- and nanoparticles for tracking in LIVE/DEAD® stained pathogenic biofilms of Staphylococcus aureus and Burkholderia cepacia.
Topics: Acetates; Biofilms; Burkholderia cepacia; Chitosan; Coumarins; Fluorescent Dyes; Lactic Acid; Microscopy, Confocal; Nanoparticles; Organic Chemicals; Polyesters; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Propidium; Staphylococcus aureus | 2016 |
Core-Shell Chitosan Microcapsules for Programmed Sequential Drug Release.
Topics: Capsules; Chitosan; Drug Liberation; Lactic Acid; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2016 |
Inhibition of Listeria monocytogenes in Fresh Cheese Using Chitosan-Grafted Lactic Acid Packaging.
Topics: Cheese; Chitin; Chitosan; Food Microbiology; Food Packaging; Humans; Lactic Acid; Listeria monocytogenes | 2016 |
A microscopy method for scanning transmission electron microscopy imaging of the antibacterial activity of polymeric nanoparticles on a biofilm with an ionic liquid.
Topics: Anti-Bacterial Agents; Biofilms; Chitosan; Ionic Liquids; Lactic Acid; Microscopy, Electron, Scanning Transmission; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Staphylococcus epidermidis | 2017 |
Improved mucoadhesion and cell uptake of chitosan and chitosan oligosaccharide surface-modified polymer nanoparticles for mucosal delivery of proteins.
Topics: Cell Survival; Chitosan; Delayed-Action Preparations; Drug Carriers; Drug Liberation; Humans; Lactic Acid; Mucous Membrane; Nanoparticles; Oligosaccharides; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Proteins; Serum Albumin, Bovine | 2016 |
Morphological study of efficacy of clarithromycin-loaded nanocarriers for treatment of biofilm infection disease.
Topics: Anti-Bacterial Agents; Biofilms; Chitosan; Clarithromycin; Colony Count, Microbial; Drug Carriers; Lactic Acid; Micelles; Microbial Viability; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Static Electricity | 2017 |
Enhancing insulin oral absorption by using mucoadhesive nanoparticles loaded with LMWP-linked insulin conjugates.
Topics: Adhesiveness; Administration, Oral; Animals; Blood Glucose; Cell Line, Tumor; Cell-Penetrating Peptides; Chitosan; Diabetes Mellitus, Experimental; Drug Liberation; Humans; Hypoglycemic Agents; Insulin; Intestinal Absorption; Intestinal Mucosa; Lactic Acid; Male; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Protamines; Rats, Wistar | 2016 |
Nanofiber mats composed of a chitosan-poly(d,l-lactic-co-glycolic acid)-poly(ethylene oxide) blend as a postoperative anti-adhesion agent.
Topics: Animals; Chitosan; Humans; Lactic Acid; Membranes, Artificial; Nanofibers; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Tissue Adhesions | 2017 |
PLGA Microparticles Entrapping Chitosan-Based Nanoparticles for the Ocular Delivery of Ranibizumab.
Topics: Acetylcysteine; Cell Line; Cell Movement; Cell Survival; Chitosan; Drug Delivery Systems; Human Umbilical Vein Endothelial Cells; Humans; Hyaluronic Acid; Lactic Acid; Macular Degeneration; Magnetic Resonance Spectroscopy; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polyphosphates; Ranibizumab; Spectroscopy, Fourier Transform Infrared | 2016 |
CS/PAA@TPGS/PLGA nanoparticles with intracellular pH-sensitive sequential release for delivering drug to the nucleus of MDR cells.
Topics: Acrylic Resins; Autophagy; Cell Line; Cell Nucleus; Chitosan; Drug Delivery Systems; Humans; Hydrogen-Ion Concentration; Lactic Acid; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2016 |
Injectable PLGA/Hydroxyapatite/Chitosan Microcapsules Produced by Supercritical Emulsion Extraction Technology: An In Vitro Study on Teriparatide/Gentamicin Controlled Release.
Topics: Bone Density Conservation Agents; Capsules; Chitosan; Chromatography, Supercritical Fluid; Delayed-Action Preparations; Durapatite; Emulsions; Excipients; Gentamicins; Kinetics; Lactic Acid; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Protein Synthesis Inhibitors; Solubility; Teriparatide | 2016 |
Biodistribution and toxicity of orally administered poly (lactic-co-glycolic) acid nanoparticles to F344 rats for 21 days.
Topics: Administration, Oral; Alanine Transaminase; Alkaline Phosphatase; Animals; Chitosan; Drug Carriers; Humans; Lactic Acid; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats, Inbred F344; Surface Properties; Tissue Distribution; Toxicity Tests, Subacute | 2016 |
Toxicity, pharmacokinetics, and in vivo efficacy of biotinylated chitosan surface-modified PLGA nanoparticles for tumor therapy.
Topics: Animals; Biotinylation; Chitosan; Drug Delivery Systems; Female; Lactic Acid; Mice; Neoplasms, Experimental; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Wistar | 2017 |
Transient aggregation of chitosan-modified poly(d,l-lactic-co-glycolic) acid nanoparticles in the blood stream and improved lung targeting efficiency.
Topics: Animals; Chitosan; Female; Humans; Lactic Acid; Lung; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Surface Properties; Tissue Distribution | 2016 |
Thyrotropin-Releasing Hormone Loaded and Chitosan Engineered Polymeric Nanoparticles: Towards Effective Delivery of Neuropeptides.
Topics: Absorption, Physicochemical; Chitosan; Delayed-Action Preparations; Diffusion; Drug Compounding; Lactic Acid; Nanocapsules; Neuropeptides; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Thyrotropin-Releasing Hormone | 2016 |
Transplantation of Mesenchymal Stem Cells for Acute Spinal Cord Injury in Rats: Comparative Study between Intralesional Injection and Scaffold Based Transplantation.
Topics: Animals; Bone Marrow Cells; Brain-Derived Neurotrophic Factor; Cell Differentiation; Cells, Cultured; Chitosan; Immunophenotyping; Injections, Intralesional; Lactic Acid; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Microscopy, Fluorescence; Nerve Growth Factors; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Recovery of Function; Spinal Cord; Spinal Cord Injuries; Tissue Scaffolds; Transplantation, Homologous | 2016 |
Pulmonary pharmacokinetics of levofloxacin in rats after aerosolization of immediate-release chitosan or sustained-release PLGA microspheres.
Topics: Administration, Inhalation; Aerosols; Animals; Anti-Bacterial Agents; Chitosan; Delayed-Action Preparations; Lactic Acid; Levofloxacin; Male; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats, Sprague-Dawley | 2016 |
Poly(D,L-Lactide-Co-Glycolide) Tubes With Multifilament Chitosan Yarn or Chitosan Sponge Core in Nerve Regeneration.
Topics: Animals; Chitosan; Guided Tissue Regeneration; Lactic Acid; Male; Nerve Regeneration; Outcome Assessment, Health Care; Peripheral Nerve Injuries; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Wistar; Sciatic Nerve; Tissue Scaffolds | 2016 |
Blow-spun chitosan/PEG/PLGA nanofibers as a novel tissue engineering scaffold with antibacterial properties.
Topics: Animals; Anti-Bacterial Agents; Cell Proliferation; Cells, Cultured; Chitosan; Epithelial Cells; Keratins; Lactic Acid; Microbial Sensitivity Tests; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Nanofibers; Polyesters; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polystyrenes; Rats; Streptococcus mutans; Temperature; Thermogravimetry; Tissue Engineering; Tissue Scaffolds | 2016 |
Surface-functionalized, pH-responsive poly(lactic-co-glycolic acid)-based microparticles for intranasal vaccine delivery: Effect of surface modification with chitosan and mannan.
Topics: Administration, Intranasal; Animals; Antigens; Chitosan; Drug Carriers; Drug Delivery Systems; Emulsions; Endosomes; Female; Glycols; Hepatitis B Surface Antigens; Hydrogen-Ion Concentration; Lactic Acid; Lysosomes; Macrophages; Macrophages, Peritoneal; Mannans; Mice; Microspheres; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Surface Properties; Vaccines | 2016 |
Effect of PEG and water-soluble chitosan coating on moxifloxacin-loaded PLGA long-circulating nanoparticles.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Chitosan; Drug Carriers; Drug Liberation; Fluoroquinolones; Lactic Acid; Male; Microscopy, Electron, Transmission; Moxifloxacin; Nanoparticles; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats, Wistar; Solubility; Tissue Distribution; Topoisomerase II Inhibitors; Water | 2017 |
Chitosan-modified PLGA polymeric nanocarriers with better delivery potential for tamoxifen.
Topics: Administration, Topical; Animals; Breast Neoplasms; Chitosan; Drug Carriers; Female; Humans; Lactic Acid; MCF-7 Cells; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Skin Absorption; Tamoxifen | 2016 |
Magnetic core-shell hybrid nanoparticles for receptor targeted anti-cancer therapy and magnetic resonance imaging.
Topics: Antineoplastic Agents; Carbodiimides; Cell Line, Tumor; Chitosan; Contrast Media; Cross-Linking Reagents; Docetaxel; Drug Compounding; Drug Liberation; Epithelial Cells; Ferric Compounds; Folate Receptor 1; Folic Acid; Gene Expression; Humans; Hydrogen-Ion Concentration; Kinetics; Lactic Acid; Magnetic Resonance Imaging; Magnetite Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Taxoids | 2017 |
Chitosan-coated PLGA nanoparticles of bevacizumab as novel drug delivery to target retina: optimization, characterization, and in vitro toxicity evaluation.
Topics: Adhesiveness; Animals; Bevacizumab; Chickens; Chitosan; Drug Carriers; Drug Liberation; Lactic Acid; Materials Testing; Mucous Membrane; Nanoparticles; Particle Size; Permeability; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Retina; Swine | 2017 |
Chitosan/nHAC/PLGA microsphere vehicle for sustained release of rhBMP-2 and its derived synthetic oligopeptide for bone regeneration.
Topics: Animals; Bone Morphogenetic Protein 2; Bone Regeneration; Cell Line; Chitosan; Collagen; Delayed-Action Preparations; Durapatite; Humans; Lactic Acid; Male; Mice; Microspheres; Osteoblasts; Osteogenesis; Peptides; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Skull; Transforming Growth Factor beta | 2017 |
Raloxifene microsphere-embedded collagen/chitosan/β-tricalcium phosphate scaffold for effective bone tissue engineering.
Topics: Animals; Bone Density Conservation Agents; Calcium Phosphates; Cell Line; Cell Survival; Chitosan; Collagen; Lactic Acid; Mice; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Tissue Engineering; Tissue Scaffolds | 2017 |
CD73 specific siRNA loaded chitosan lactate nanoparticles potentiate the antitumor effect of a dendritic cell vaccine in 4T1 breast cancer bearing mice.
Topics: 5'-Nucleotidase; Animals; Breast; Breast Neoplasms; Cancer Vaccines; Cell Line, Tumor; Chitosan; Dendritic Cells; Female; Genetic Therapy; Immunotherapy; Lactic Acid; Mice; Mice, Inbred BALB C; Nanoparticles; RNA, Small Interfering; RNAi Therapeutics | 2017 |
Sequential delivery of chlorhexidine acetate and bFGF from PLGA-glycol chitosan core-shell microspheres.
Topics: 3T3 Cells; Animals; Anti-Bacterial Agents; Biocompatible Materials; Cell Proliferation; Chitosan; Chlorhexidine; Drug Delivery Systems; Fibroblast Growth Factor 2; Glycols; Lactic Acid; Mice; Microscopy, Electron, Scanning; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Wound Healing | 2017 |
Enhancing the in vitro anticancer activity of albendazole incorporated into chitosan-coated PLGA nanoparticles.
Topics: Albendazole; Cell Survival; Chitosan; Drug Carriers; Lactic Acid; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2017 |
Evaluation of Magnetic Nanoparticle-Labeled Chondrocytes Cultivated on a Type II Collagen-Chitosan/Poly(Lactic-co-Glycolic) Acid Biphasic Scaffold.
Topics: Animals; Cells, Cultured; Chitosan; Chondrocytes; Chondrogenesis; Collagen Type II; Lactic Acid; Magnetite Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rabbits; Tissue Engineering; Tissue Scaffolds | 2017 |
Chitosan-based water-propelled micromotors with strong antibacterial activity.
Topics: Alginates; Anti-Bacterial Agents; Biocompatible Materials; Chitosan; Drinking Water; Escherichia coli; Glucuronic Acid; Hexuronic Acids; Lactic Acid; Magnesium; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Water; Water Purification | 2017 |
Lactate Detection in Tumor Cell Cultures Using Organic Transistor Circuits.
Topics: Animals; Biosensing Techniques; Calibration; Cattle; Cell Culture Techniques; Chitosan; Electric Impedance; Electrochemical Techniques; Equipment Design; Ferrous Compounds; Humans; Lactic Acid; Leukocytes, Mononuclear; Metallocenes; Mixed Function Oxygenases; Neoplasms; Polystyrenes; Sensitivity and Specificity; Serum Albumin, Bovine; Thiophenes; Transistors, Electronic | 2017 |
Effect of chitosan and SO
Topics: Acetic Acid; Acetobacter; Anti-Infective Agents; Chitosan; Ethanol; Food Microbiology; Lactic Acid; Sulfur Dioxide; Wine | 2017 |
Nano-carrier mediated co-delivery of methyl prednisolone and minocycline for improved post-traumatic spinal cord injury conditions in rats.
Topics: Albumins; Animals; Anti-Inflammatory Agents; Astrocytes; Behavior, Animal; Cell Survival; Chitosan; Drug Carriers; Drug Combinations; Drug Delivery Systems; Female; Lactic Acid; Methylprednisolone; Minocycline; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries | 2017 |
Assessment of penetration potential of pH responsive double walled biodegradable nanogels coated with eucalyptus oil for the controlled delivery of 5-fluorouracil: In vitro and ex vivo studies.
Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Cell Line; Cell Survival; Chitosan; Delayed-Action Preparations; Drug Liberation; Eucalyptus; Fluorouracil; Gels; Hemolysis; Humans; Hydrogen-Ion Concentration; Lactic Acid; Nanostructures; Plant Oils; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Skin; Skin Absorption; Swine | 2017 |
Thermogelling chitosan lactate hydrogel improves functional recovery after a C2 spinal cord hemisection in rat.
Topics: Animals; Cell Line; Chitosan; Hydrogels; Lactic Acid; Male; Mice; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries | 2017 |
Reconstruction of Large-scale Defects with a Novel Hybrid Scaffold Made from Poly(L-lactic acid)/Nanohydroxyapatite/Alendronate-loaded Chitosan Microsphere: in vitro and in vivo Studies.
Topics: Alendronate; Animals; Bone Regeneration; Bone Substitutes; Cells, Cultured; Chitosan; Drug Delivery Systems; Durapatite; In Vitro Techniques; Lactic Acid; Microspheres; Osteogenesis; Rabbits; Tissue Engineering; Tissue Scaffolds | 2017 |
Co-delivery nanoparticles with characteristics of intracellular precision release drugs for overcoming multidrug resistance.
Topics: Alginates; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Chitosan; Doxorubicin; Drug Carriers; Drug Delivery Systems; Drug Liberation; Drug Resistance, Multiple; Emulsions; Glucuronic Acid; Hexuronic Acids; Humans; Lactic Acid; Mice, Nude; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Vincristine; Vitamin E; Xenograft Model Antitumor Assays | 2017 |
Chitosan-modified PLGA nanoparticles tagged with 5TR1 aptamer for in vivo tumor-targeted drug delivery.
Topics: Adsorption; Animals; Antibiotics, Antineoplastic; Aptamers, Nucleotide; Cell Survival; Chitosan; CHO Cells; Colonic Neoplasms; Cricetulus; Drug Carriers; Drug Compounding; Drug Liberation; Epirubicin; Female; Humans; Lactic Acid; MCF-7 Cells; Mice, Inbred BALB C; Mucin-1; Nanomedicine; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solubility; Surface Properties; Technology, Pharmaceutical; Time Factors; Tumor Burden | 2017 |
Doxorubicin-loaded poly (lactic-co-glycolic acid) nanoparticles coated with chitosan/alginate by layer by layer technology for antitumor applications.
Topics: Alginates; Animals; Antineoplastic Agents; Chitosan; Doxorubicin; Drug Delivery Systems; Drug Liberation; Drug Screening Assays, Antitumor; Glucuronic Acid; Hexuronic Acids; Hydrogen-Ion Concentration; Lactic Acid; Male; Mice; Microscopy, Atomic Force; Microscopy, Electron, Transmission; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; X-Ray Diffraction | 2017 |
The generation of compartmentalized nanoparticles containing siRNA and cisplatin using a multi-needle electrohydrodynamic strategy.
Topics: Chitosan; Cisplatin; Drug Carriers; Lactic Acid; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; RNA, Small Interfering | 2017 |
Protective efficacy of cationic-PLGA microspheres loaded with DNA vaccine encoding the sip gene of Streptococcus agalactiae in tilapia.
Topics: Animals; Bacterial Vaccines; Chitosan; Fish Diseases; Genes, Bacterial; Immunity, Innate; Immunogenicity, Vaccine; Lactic Acid; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Random Allocation; Streptococcal Infections; Streptococcus agalactiae; Tilapia; Tissue Distribution; Vaccines, DNA | 2017 |
Novel Superparamagnetic Microdevices Based on Magnetized PLGA/PLA Microparticles Obtained by Supercritical Fluid Emulsion and Coating by Carboxybetaine-Functionalized Chitosan Allowing the Tuneable Release of Therapeutics.
Topics: Betaine; Chitosan; Delayed-Action Preparations; Drug Liberation; Emulsions; Fluorescent Dyes; Lactic Acid; Magnetic Fields; Magnetite Nanoparticles; Magnets; Particle Size; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2017 |
Surface biofunctionalization of three-dimensional porous poly(lactic acid) scaffold using chitosan/OGP coating for bone tissue engineering.
Topics: Bone and Bones; Chitosan; Lactic Acid; Polyesters; Porosity; Tissue Engineering; Tissue Scaffolds | 2017 |
Preparation of poly(lactic-co-glycolic acid) and chitosan composite nanocarriers via electrostatic self assembly for oral delivery of insulin.
Topics: Administration, Oral; Animals; Chitosan; Diabetes Mellitus, Experimental; Drug Carriers; Insulin; Lactic Acid; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats | 2017 |
In vitro and in vivo assessment of lactic acid-modified chitosan scaffolds for potential treatment of full-thickness burns.
Topics: Animals; Biocompatible Materials; Burns; Cells, Cultured; Chitosan; Fibroblasts; Humans; Lactic Acid; Male; Mice; Mice, Nude; Skin; Tissue Scaffolds; Wound Healing | 2017 |
Oleanolic-bioenhancer coloaded chitosan modified nanocarriers attenuate breast cancer cells by multimode mechanism and preserve female fertility.
Topics: Animals; Antineoplastic Agents; Apoptosis; Caspases; Chitosan; Drug Carriers; Drug Liberation; Enzyme Activation; Female; Fertility; Humans; Lactic Acid; Mice; Nanoparticles; Oleanolic Acid; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats | 2017 |
Sequential IGF-1 and BMP-6 releasing chitosan/alginate/PLGA hybrid scaffolds for periodontal regeneration.
Topics: Alginates; Biocompatible Materials; Bone Morphogenetic Protein 6; Cell Proliferation; Chitosan; Gene Expression Regulation; Glucuronic Acid; Hexuronic Acids; Insulin-Like Growth Factor I; Lactic Acid; Microspheres; Minerals; Periodontium; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Regeneration; Tissue Scaffolds | 2017 |
Bioconversion of shrimp waste Penaeus merguiensis using lactic acid fermentation: An alternative procedure for chemical extraction of chitin and chitosan.
Topics: Animals; Chitin; Chitosan; Fermentation; Lactic Acid; Penaeidae; Pseudomonas aeruginosa; Waste Products | 2017 |
Chitosan whisker grafted with oligo(lactic acid) nanoparticles via a green synthesis pathway: Potential as a transdermal drug delivery system.
Topics: Administration, Cutaneous; Anesthetics, Local; Cell Line; Chitosan; Drug Carriers; Drug Delivery Systems; Green Chemistry Technology; Humans; Lactic Acid; Lidocaine; Nanoparticles; Skin Absorption | 2017 |
A dual-application poly (dl-lactic-co-glycolic) acid (PLGA)-chitosan composite scaffold for potential use in bone tissue engineering.
Topics: Biocompatible Materials; Bone and Bones; Bone Morphogenetic Protein 2; Calcification, Physiologic; Cell Proliferation; Chitosan; Humans; Injections; Kinetics; Lactic Acid; Mesenchymal Stem Cells; Microspheres; Osteocalcin; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Serum Albumin, Bovine; Tissue Engineering; Tissue Scaffolds | 2017 |
Modulation of periodontitis progression using pH-responsive nanosphere encapsulating metronidazole or N-phenacylthialzolium bromide.
Topics: Animals; Anti-Infective Agents; Chitosan; Disease Models, Animal; Disease Progression; Lactic Acid; Metronidazole; Nanospheres; Periodontitis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats, Sprague-Dawley; Thiazoles | 2018 |
A novel vehicle for local protein delivery to the inner ear: injectable and biodegradable thermosensitive hydrogel loaded with PLGA nanoparticles.
Topics: Animals; Chitosan; Drug Delivery Systems; Ear, Inner; Excipients; Glycerophosphates; Guinea Pigs; Hydrogel, Polyethylene Glycol Dimethacrylate; Interferon alpha-2; Interferon-alpha; Lactic Acid; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Recombinant Proteins | 2018 |
Irinotecan and 5-fluorouracil-co-loaded, hyaluronic acid-modified layer-by-layer nanoparticles for targeted gastric carcinoma therapy.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cell Line, Tumor; Chemistry, Pharmaceutical; Chitosan; Drug Carriers; Drug Delivery Systems; Fluorouracil; Humans; Hyaluronic Acid; Irinotecan; Lactic Acid; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Stomach Neoplasms | 2017 |
Co-delivery of polyinosinic:polycytidylic acid and flagellin by poly(lactic-
Topics: Administration, Intranasal; Animals; Chitosan; Drug Carriers; Drug Synergism; Female; Flagellin; Hepatitis B Surface Antigens; Interferon-gamma; Interleukin-10; Interleukin-12; Lactic Acid; Macrophages; Microspheres; Poly I-C; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats, Sprague-Dawley | 2017 |
Fabrication of Antimicrobial Peptide-Loaded PLGA/Chitosan Composite Microspheres for Long-Acting Bacterial Resistance.
Topics: Anti-Infective Agents; Antimicrobial Cationic Peptides; Bacteria; Biocompatible Materials; Chitosan; Circular Dichroism; Drug Compounding; Drug Delivery Systems; Drug Liberation; Drug Resistance, Bacterial; Drug Stability; Lactic Acid; Microspheres; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2017 |
Iontophoretic transdermal delivery using chitosan-coated PLGA nanoparticles for positively charged drugs.
Topics: Administration, Cutaneous; Animals; Chitosan; Drug Delivery Systems; Hair Follicle; Hydrophobic and Hydrophilic Interactions; Iontophoresis; Lactic Acid; Male; Nanoparticles; Particle Size; Pharmaceutical Preparations; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats, Sprague-Dawley; Skin; Surface Properties | 2017 |
Surface-modified PLGA nanoparticles with chitosan for oral delivery of tolbutamide.
Topics: Administration, Oral; Animals; Blood Glucose; Cell Survival; Chitosan; Diabetes Mellitus, Experimental; Drug Liberation; Hep G2 Cells; Humans; Hypoglycemic Agents; Lactic Acid; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats, Sprague-Dawley; Surface Properties; Tolbutamide | 2018 |
Nature derived scaffolds for tissue engineering applications: Design and fabrication of a composite scaffold incorporating chitosan-g-d,l-lactic acid and cellulose nanocrystals from Lactuca sativa L. cv green leaf.
Topics: Animals; Cell Line; Chitosan; Fibroblasts; Lactic Acid; Lactuca; Mice; Nanoparticles; Plant Leaves; Tissue Engineering; Tissue Scaffolds | 2018 |
Injectable deferoxamine nanoparticles loaded chitosan-hyaluronic acid coacervate hydrogel for therapeutic angiogenesis.
Topics: Animals; Cells, Cultured; Chitosan; Deferoxamine; Delayed-Action Preparations; Drug Liberation; Human Umbilical Vein Endothelial Cells; Humans; Hyaluronic Acid; Hydrogel, Polyethylene Glycol Dimethacrylate; Injections; Lactic Acid; Mice, Inbred BALB C; Nanoparticles; Neovascularization, Physiologic; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2018 |
Multi-tubule conduit-filler constructs loaded with gradient-distributed growth factors for neural tissue engineering applications.
Topics: Animals; Biocompatible Materials; Chitosan; Compressive Strength; Fibroins; Gels; Glycerophosphates; Lactic Acid; Microscopy, Electron, Scanning; Muramidase; Nerve Growth Factor; PC12 Cells; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Porosity; Rats; Stress, Mechanical; Temperature; Tissue Engineering | 2018 |
Small molecule delivery to solid tumors with chitosan-coated PLGA particles: A lesson learned from comparative imaging.
Topics: Animals; Cell Line, Tumor; Chitosan; Drug Carriers; Female; Humans; Lactic Acid; Magnetic Resonance Imaging; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Neoplasms; Optical Imaging; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Whole Body Imaging | 2017 |
Glycol chitosan assisted in situ reduction of gold on polymeric template for anti-cancer theranostics.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Chitosan; Female; Gold; Humans; Hyperthermia, Induced; Lactic Acid; MCF-7 Cells; Mice; Nanoshells; Oxidation-Reduction; Photochemotherapy; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Theranostic Nanomedicine | 2018 |
Chitosan-Coated Poly(lactic-co-glycolic acid)-Diiodinated boron-Dipyrromethene Nanoparticles Improve Tumor Selectivity and Stealth Properties in Photodynamic Cancer Therapy.
Topics: Animals; Antineoplastic Agents; Boron Compounds; Cell Line, Tumor; Cell Survival; Chitosan; Drug Carriers; Female; Humans; Iodine; Lactic Acid; Mice; Mice, Inbred BALB C; Nanoparticles; Photochemotherapy; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Porphobilinogen; Tissue Distribution | 2016 |
Construction and optimization of pH-sensitive nanoparticle delivery system containing PLGA and UCCs-2 for targeted treatment of Helicobacter pylori.
Topics: Amoxicillin; Animals; Cell Death; Chitosan; Drug Delivery Systems; Drug Liberation; HEK293 Cells; Helicobacter pylori; Humans; Hydrogen-Ion Concentration; Lactic Acid; Male; Mice, Inbred BALB C; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Stomach; Urea | 2018 |
Intranasal delivery of Huperzine A to the brain using lactoferrin-conjugated N-trimethylated chitosan surface-modified PLGA nanoparticles for treatment of Alzheimer's disease.
Topics: Administration, Intranasal; Alkaloids; Alzheimer Disease; Animals; Brain; Chitosan; Drug Carriers; Drug Delivery Systems; Humans; Lactic Acid; Lactoferrin; Mice; Nanoparticles; Neuroprotective Agents; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Sesquiterpenes; Tissue Distribution | 2018 |
Chitosan Stabilized Gold-Folate-Poly(lactide-co-glycolide) Nanoplexes Facilitate Efficient Gene Delivery in Hepatic and Breast Cancer Cells.
Topics: Breast Neoplasms; Chitosan; Female; Folic Acid; Genetic Therapy; Gold; Humans; Lactic Acid; Nanoparticles; Particle Size; Polyglactin 910; Polyglycolic Acid | 2018 |
Response to the question (Ref> No.: JN2017754).
Topics: Anti-Arrhythmia Agents; Chitosan; Drug Carriers; Green Chemistry Technology; Humans; Lactic Acid; Lidocaine; Nanoparticles | 2018 |
Chitosan whisker grafted with oligo(lactic acid) nanoparticles via a green synthesis pathway and Lidocaine encapsulation: is there any forgotten issue?
Topics: Anti-Arrhythmia Agents; Chitosan; Drug Carriers; Green Chemistry Technology; Humans; Lactic Acid; Lidocaine; Nanoparticles | 2018 |
Antifungal Activity of Chitosan-Coated Poly(lactic-co-glycolic) Acid Nanoparticles Containing Amphotericin B.
Topics: Amphotericin B; Animals; Antifungal Agents; Candida; Candidemia; Candidiasis, Vulvovaginal; Chitosan; Drug Carriers; Female; Humans; Lactic Acid; Microbial Sensitivity Tests; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Trichosporon; Urinary Tract Infections | 2018 |
Evaluation of curcumin loaded chitosan/PEG blended PLGA nanoparticles for effective treatment of pancreatic cancer.
Topics: Apoptosis; Cell Death; Cell Line, Tumor; Cell Movement; Cell Survival; Chitosan; Curcumin; Endocytosis; Humans; Inhibitory Concentration 50; Lactic Acid; Nanoparticles; Neoplasm Invasiveness; Pancreatic Neoplasms; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Signal Transduction | 2018 |
[Experimental Comparison Research between Two Kinds of Modified Poly(lactic acid)Material In Vitro].
Topics: Animals; Biocompatible Materials; Cell Adhesion; Cells, Cultured; Chitosan; Lactic Acid; Neuroglia; Polyesters; Porosity; Rats; Tissue Engineering; Tissue Scaffolds | 2016 |
Chitosan coated PLGA nanoparticles amplify the ocular hypotensive effect of forskolin: Statistical design, characterization and in vivo studies.
Topics: Animals; Cell Line; Chitosan; Colforsin; Cornea; Delayed-Action Preparations; Dexamethasone; Drug Carriers; Goats; Lactic Acid; Nanoparticles; Ocular Hypotension; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rabbits | 2018 |
Therapeutic efficacy of rebamipide-loaded PLGA nanoparticles coated with chitosan in a mouse model for oral mucositis induced by cancer chemotherapy.
Topics: Alanine; Animals; Anti-Ulcer Agents; Chitosan; Coated Materials, Biocompatible; Drug Liberation; Fluorouracil; Lactic Acid; Male; Mice, Inbred ICR; Microscopy, Electron, Scanning; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Quinolones; Stomatitis; Treatment Outcome | 2018 |
Tunable sequential drug delivery system based on chitosan/hyaluronic acid hydrogels and PLGA microspheres for management of non-healing infected wounds.
Topics: Animals; Bacteria; Biocompatible Materials; Cell Proliferation; Chitosan; Cytokines; Drug Carriers; Drug Liberation; Human Umbilical Vein Endothelial Cells; Humans; Hyaluronic Acid; Hydrogels; Lactic Acid; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Porosity; Rats; Skin Diseases; Vancomycin; Vascular Endothelial Growth Factor A; Wound Healing | 2018 |
The effect of the androstane lung cancer inhibitor content on the cell-selective toxicity of hydroxyapatite-chitosan-PLGA nanocomposites.
Topics: A549 Cells; Androstanes; Calorimetry, Differential Scanning; Cell Line; Cell Survival; Chitosan; Drug Carriers; Drug Liberation; Durapatite; Humans; Lactic Acid; Lung Neoplasms; Microscopy, Atomic Force; Nanocomposites; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Spectroscopy, Fourier Transform Infrared | 2018 |
Mucus-penetrating nanoparticles: Promising drug delivery systems for the photodynamic therapy of intestinal cancer.
Topics: Administration, Oral; Caco-2 Cells; Chitosan; Drug Delivery Systems; Humans; Intestinal Mucosa; Intestinal Neoplasms; Lactic Acid; Mucus; Nanoparticles; Permeability; Photochemotherapy; Photosensitizing Agents; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Porphyrins | 2018 |
Improved design and characterization of PLGA/PLA-coated Chitosan based micro-implants for controlled release of hydrophilic drugs.
Topics: Antimetabolites, Antineoplastic; Chitosan; Delayed-Action Preparations; Drug Design; Drug Implants; Drug Liberation; Hydrophobic and Hydrophilic Interactions; Lactic Acid; Methotrexate; Molecular Weight; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2018 |
Improvement of oral efficacy of Irinotecan through biodegradable polymeric nanoparticles through in vitro and in vivo investigations.
Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Biological Availability; Brain; Caco-2 Cells; Camptothecin; Chitosan; Drug Carriers; Humans; Intestinal Absorption; Irinotecan; Lactic Acid; Male; MCF-7 Cells; Nanoparticles; Neoplasms; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Wistar | 2018 |
Intra-Articular Formulation of GE11-PLGA Conjugate-Based NPs for Dexamethasone Selective Targeting-In Vitro Evaluation.
Topics: Animals; Chitosan; Dexamethasone; ErbB Receptors; Humans; Hydrogel, Polyethylene Glycol Dimethacrylate; Lactic Acid; Nanoparticles; Peptides; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2018 |
Novel docetaxel chitosan-coated PLGA/PCL nanoparticles with magnified cytotoxicity and bioavailability.
Topics: Animals; Antineoplastic Agents; Biological Availability; Cell Survival; Chitosan; Colorectal Neoplasms; Delayed-Action Preparations; Docetaxel; Drug Carriers; Drug Compounding; Drug Liberation; Dynamic Light Scattering; HT29 Cells; Humans; Injections, Intraperitoneal; Lactic Acid; Male; Microscopy, Electron, Scanning; Nanoparticles; Nanotechnology; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats, Wistar; Solubility; Spectroscopy, Fourier Transform Infrared; Taxoids; Technology, Pharmaceutical | 2018 |
Chitosan-functionalized lipid-polymer hybrid nanoparticles for oral delivery of silymarin and enhanced lipid-lowering effect in NAFLD.
Topics: Administration, Oral; Animals; Biological Availability; Biological Transport; Caco-2 Cells; Chitosan; Delayed-Action Preparations; Drug Carriers; Drug Liberation; Female; Hep G2 Cells; Humans; Lactic Acid; Lipids; Liver; Male; Mice; Mice, Transgenic; Molecular Structure; Nanoparticles; Non-alcoholic Fatty Liver Disease; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Wistar; Silymarin; Surface Properties | 2018 |
Kinetics of mRNA delivery and protein translation in dendritic cells using lipid-coated PLGA nanoparticles.
Topics: A549 Cells; Chitosan; Dendritic Cells; Humans; Kinetics; Lactic Acid; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Protein Biosynthesis; RNA, Messenger; Stearic Acids; Transfection | 2018 |
Non-invasive textile based colorimetric sensor for the simultaneous detection of sweat pH and lactate.
Topics: Azo Compounds; Bromcresol Green; Calibration; Carboxymethylcellulose Sodium; Chitosan; Color; Colorimetry; Hydrogen-Ion Concentration; Lactic Acid; Sweat | 2019 |
Separate and combined effects of lactic acid, chitosan and modified atmosphere packaging on the shelf life of quail carcass under chilled conditions.
Topics: Animals; Atmosphere; Bacteria; Chitosan; Color; Food Microbiology; Food Packaging; Food Storage; Lactic Acid; Meat; Nitrogen; Quail | 2019 |
Insights on physicochemical aspects of chitosan dispersion in aqueous solutions of acetic, glycolic, propionic or lactic acid.
Topics: Acetic Acid; Acetylation; Chemical Phenomena; Chitosan; Electric Conductivity; Glycolates; Hydrogen-Ion Concentration; Lactic Acid; Molecular Weight; Rheology; Solutions; Viscosity | 2019 |
Microbial production of high value molecules using rayon waste material as carbon-source.
Topics: Aspergillus niger; Biomass; Biotechnology; Carbon; Cellulose; Chitosan; Escherichia coli; Glucose; Lactic Acid; Lacticaseibacillus paracasei; Succinates; Waste Products | 2019 |
Inhibiting hepatic gluconeogenesis by chitosan lactate nanoparticles containing CRTC2 siRNA targeted by poly(ethylene glycol)-glycyrrhetinic acid.
Topics: Animals; Chitosan; Diabetes Mellitus, Experimental; Gene Expression; Gluconeogenesis; Glycyrrhetinic Acid; Hep G2 Cells; Humans; Lactic Acid; Liver; Male; Nanoparticles; Polyethylene Glycols; Rats, Wistar; RNA, Small Interfering; Tissue Distribution; Transcription Factors | 2019 |
Downregulation of A2AR by siRNA loaded PEG-chitosan-lactate nanoparticles restores the T cell mediated anti-tumor responses through blockage of PKA/CREB signaling pathway.
Topics: Animals; Biological Transport; Cell Differentiation; Cell Line, Tumor; Chitosan; Cyclic AMP Response Element-Binding Protein; Cyclic AMP-Dependent Protein Kinases; Down-Regulation; Drug Carriers; Drug Stability; Gene Silencing; Humans; Lactic Acid; Mice; Nanoparticles; Polyethylene Glycols; Receptor, Adenosine A2A; RNA, Small Interfering; Signal Transduction; T-Lymphocytes; T-Lymphocytes, Regulatory | 2019 |
Silencing adenosine A2a receptor enhances dendritic cell-based cancer immunotherapy.
Topics: Adenosine A2 Receptor Antagonists; Animals; Breast Neoplasms; Cancer Vaccines; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Chitosan; Dendritic Cells; Disease Models, Animal; Female; Gene Expression Regulation, Neoplastic; Humans; Immunotherapy; Lactic Acid; Mammary Neoplasms, Animal; Mice; Nanoparticles; Polyethylene Glycols; Receptor, Adenosine A2A; RNA, Small Interfering; T-Lymphocytes, Cytotoxic | 2020 |
Biodegradable poly (lactic acid-co-trimethylene carbonate)/chitosan microsphere scaffold with shape-memory effect for bone tissue engineering.
Topics: Chitosan; Dioxanes; Lactic Acid; Microspheres; Polyesters; Porosity; Tissue Engineering; Tissue Scaffolds | 2020 |
Effect of edible composite film based on chitosan and cumin essential oil-loaded nanoemulsion combined with low-dose gamma irradiation on microbiological safety and quality of beef loins during refrigerated storage.
Topics: Animals; Antioxidants; Cattle; Chitosan; Cuminum; Edible Films; Emulsions; Enterobacteriaceae; Escherichia coli; Food Contamination; Food Microbiology; Food Preservation; Food Storage; Gamma Rays; Gastrointestinal Microbiome; Hydrogen-Ion Concentration; Lactic Acid; Listeria monocytogenes; Meat; Nanoparticles; Nitrogen; Oils, Volatile; Particle Size; Red Meat; Refrigeration; Salmonella typhimurium; Temperature; Thiobarbituric Acid Reactive Substances; Time Factors | 2020 |
Near-infra-red fluorescent chitosan oligosaccharide lactate for targeted cancer imaging and photothermal therapy.
Topics: Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Chitosan; Fluorescent Dyes; Humans; Infrared Rays; Lactic Acid; Mice; Oligosaccharides; Optical Imaging; Phototherapy | 2020 |
Codelivery of BV6 and anti-IL6 siRNA by hyaluronate-conjugated PEG-chitosan-lactate nanoparticles inhibits tumor progression.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Chick Embryo; Chitosan; Colonic Neoplasms; Drug Delivery Systems; Drug Liberation; Female; Humans; Interleukin-6; Lactic Acid; Magnetic Resonance Spectroscopy; Mice, Inbred BALB C; Nanoparticles; Neovascularization, Pathologic; Oligopeptides; Polyethylene Glycols; RNA, Small Interfering; Spectroscopy, Fourier Transform Infrared; Xenograft Model Antitumor Assays | 2020 |
Development of biobased multilayer films with improved compatibility between polylactic acid-chitosan as a function of transition coating of SiOx.
Topics: Anti-Bacterial Agents; Chitosan; Food Packaging; Lactic Acid; Oxides; Polyesters; Polymers; Silicon Dioxide; Tensile Strength | 2020 |
Improving cellular uptake and cytotoxicity of chitosan-coated poly(lactic-
Topics: Chitosan; Drug Carriers; Glycols; Lactic Acid; Macrophages; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2020 |
Chitosan Oligosaccharide Lactate-Coated Ultrasmall Gadolinium Oxide Nanoparticles: Synthesis,
Topics: Chitosan; Contrast Media; Gadolinium; Lactic Acid; Magnetic Resonance Imaging; Nanoparticles; Oligosaccharides | 2021 |
Multilayer fibroin/chitosan oligosaccharide lactate and pullulan immunomodulatory patch for treatment of hernia and prevention of intraperitoneal adhesion.
Topics: Abdominal Wall; Animals; Cell Adhesion; Cell Survival; Chitosan; Fibroins; Glucans; Hernia, Abdominal; Humans; Hydrogels; Immunomodulation; Lactic Acid; Mice; Oligosaccharides; Peritoneum; Polypropylenes; RAW 264.7 Cells; Surgical Mesh; Tissue Adhesions | 2021 |
Evaluation of easy-removing antioxidant films of chitosan with Melaleuca alternifolia essential oil.
Topics: Antioxidants; Benzothiazoles; Biphenyl Compounds; Chitosan; Color; Elastic Modulus; Food Packaging; Lactic Acid; Malates; Picrates; Solubility; Solvents; Sulfonic Acids; Surface Properties; Tea Tree Oil; Tensile Strength; Water | 2021 |
Surface-modified polylactic acid nanospheres with chitosan for antibacterial activity of 1, 2-benzisothiazolin-3-one.
Topics: Anti-Bacterial Agents; Chitosan; Escherichia coli; Humans; Lactic Acid; Microscopy, Electron, Scanning; Nanospheres; Oxidative Stress; Particle Size; Polyesters; Reactive Oxygen Species; Staphylococcus aureus; Thiazoles | 2021 |
[Preparation and Release Properties of
Topics: Chitosan; Glycols; Helicobacter pylori; Lactic Acid; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Recombinant Proteins | 2021 |
Preparation and Characterization of Docetaxel-PLGA Nanoparticles Coated with Folic Acid-chitosan Conjugate for Cancer Treatment.
Topics: Chitosan; Docetaxel; Folic Acid; Humans; Lactic Acid; Nanoparticles; Neoplasms; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2022 |
Simultaneous silencing of the A2aR and PD-1 immune checkpoints by siRNA-loaded nanoparticles enhances the immunotherapeutic potential of dendritic cell vaccine in tumor experimental models.
Topics: Animals; Apoptosis; Breast Neoplasms; Cell Proliferation; Chitosan; Colorectal Neoplasms; Combined Modality Therapy; Dendritic Cells; Female; Humans; Immunotherapy; Lactic Acid; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Programmed Cell Death 1 Receptor; Receptor, Adenosine A2A; RNA, Small Interfering; Tumor Cells, Cultured; Vaccines; Xenograft Model Antitumor Assays | 2022 |
Enhanced Anti-Proliferative Effect of Carboplatin in Ovarian Cancer Cells Exploiting Chitosan-Poly (Lactic Glycolic Acid) Nanoparticles.
Topics: Carboplatin; Chitosan; Drug Carriers; Female; Glycols; Humans; Lactic Acid; Nanoparticles; Ovarian Neoplasms; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2023 |
Theranostic nanoplatforms of emodin-chitosan with blue laser light on enhancing the anti-biofilm activity of photodynamic therapy against Streptococcus mutans biofilms on the enamel surface.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Biofilms; Chitosan; Dental Caries; Dental Enamel; Emodin; Humans; Lactic Acid; Lasers; Photochemotherapy; Photosensitizing Agents; Precision Medicine; Reactive Oxygen Species; Streptococcus mutans | 2022 |
Controlled synthesis of in-situ gold nanoparticles onto chitosan functionalized PLGA nanoparticles for oral insulin delivery.
Topics: Animals; Chitosan; Diabetes Mellitus, Experimental; Drug Carriers; Glycols; Gold; Insulin; Lactic Acid; Metal Nanoparticles; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats | 2022 |
Poly (lactic acid)-based pH responsive membrane combined with chitosan and alizarin for food packaging.
Topics: Anthraquinones; Anti-Bacterial Agents; Chitosan; Escherichia coli; Food Packaging; Hydrogen-Ion Concentration; Lactic Acid; Polyesters | 2022 |
In vitro antimicrobial effects of chitosan on microcosm biofilms of oral candidiasis.
Topics: Acrylic Resins; Antifungal Agents; Biofilms; Candida albicans; Candidiasis, Oral; Chitosan; Chlorhexidine; Humans; Lactic Acid; Miconazole; Nystatin; Stomatitis, Denture | 2022 |
Optimization and Characterization of Low-Molecular-Weight Chitosan-Coated Baicalin mPEG-PLGA Nanoparticles for the Treatment of Cataract.
Topics: Animals; Cataract; Chitosan; Drug Carriers; Lactic Acid; Nanoparticles; Particle Size; Polyethylene Glycols; Rabbits | 2022 |
Chitosan/Lactic Acid Systems: Liquid Crystalline Behavior, Rheological Properties, and Riboflavin Release In Vitro.
Topics: Chitosan; Ions; Lactic Acid; Liquid Crystals; Rheology; Riboflavin | 2022 |
The optimization of PLGA knitted mesh reinforced-collagen/chitosan scaffold for the healing of full-thickness skin defects.
Topics: Animals; Chitosan; Collagen; Lactic Acid; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Surgical Mesh; Tissue Scaffolds; Transforming Growth Factor beta1; Transforming Growth Factor beta3; Vascular Endothelial Growth Factor A | 2023 |
Inherently acidic films based on chitosan lactate-doped starches and pullulan as carries of nisin: A comparative study of controlled-release and antimicrobial properties.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Chitosan; Delayed-Action Preparations; Lactic Acid; Nisin; Staphylococcus aureus; Starch | 2023 |
Preparation of fully bio-based multilayers composed of heparin-like carboxymethylcellulose sodium and chitosan to functionalize poly (l-lactic acid) film for cardiovascular implant applications.
Topics: Anti-Bacterial Agents; Biocompatible Materials; Carboxymethylcellulose Sodium; Chitosan; Heparin; Lactic Acid; Polyesters; Surface Properties | 2023 |
Multifunctional porous poly (L-lactic acid) nanofiber membranes with enhanced anti-inflammation, angiogenesis and antibacterial properties for diabetic wound healing.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Chitosan; Diabetes Mellitus; Humans; Lactic Acid; Nanofibers; Polyesters; Porosity; Vascular Endothelial Growth Factor A; Wound Healing | 2023 |
Lawsone encapsulated polylactic-co-glycolic acid nanoparticles modified with chitosan-folic acid successfully inhibited cell growth and triggered apoptosis in Panc-1 cancer cells.
Topics: Apoptosis; bcl-2-Associated X Protein; Chitosan; Drug Carriers; Folic Acid; Glycols; Lactic Acid; Nanoparticles; Neoplasms; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2023 |
Bringing pathology to nanomedicine: a comparison of in vivo toxicity of polymeric nanoparticle carriers with and without chitosan coating.
Topics: Animals; Chitosan; Humans; Lactic Acid; Nanomedicine; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Wistar | 2023 |
3D printed Styrax Liquidus (Liquidambar orientalis Miller)-loaded poly (L-lactic acid)/chitosan based wound dressing material: Fabrication, characterization, and biocompatibility results.
Topics: Anti-Infective Agents; Bandages; Chitosan; Humans; Lactic Acid; Liquidambar; Polyesters; Printing, Three-Dimensional; Spectroscopy, Fourier Transform Infrared; Styrax; Tissue Scaffolds | 2023 |
Space Station-like Composite Nanoparticles for Co-Delivery of Multiple Natural Compounds from Chinese Medicine and Hydrogen in Combating Sensorineural Hearing Loss.
Topics: Aminoglycosides; Animals; Chitosan; Cisplatin; Guinea Pigs; Hearing Loss, Sensorineural; Hydrogen; Lactic Acid; Medicine, Chinese Traditional; Nanoparticles; Reactive Oxygen Species | 2023 |
An influence of molecular weight, deacetylation degree of chitosan xerogels on their antimicrobial activity and cytotoxicity. Comparison of chitosan materials obtained using lactic acid and CO
Topics: Anti-Infective Agents; Carbon Dioxide; Chitosan; Escherichia coli; Lactic Acid; Molecular Weight | 2023 |
Valorization of shrimp processing waste-derived chitosan into anti-inflammatory chitosan-oligosaccharides (CHOS).
Topics: Animals; Anti-Inflammatory Agents; Chitosan; Crustacea; Glycoside Hydrolases; Humans; Inflammation; Lactic Acid; Oligosaccharides | 2024 |