lactic acid has been researched along with alpha-cyano-4-hydroxycinnamate in 77 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (10.39) | 18.7374 |
| 1990's | 18 (23.38) | 18.2507 |
| 2000's | 25 (32.47) | 29.6817 |
| 2010's | 23 (29.87) | 24.3611 |
| 2020's | 3 (3.90) | 2.80 |
| Authors | Studies |
|---|---|
| Coetzee, WA | 1 |
| Best, L; Tomlinson, S; Trebilcock, R | 1 |
| Nikiforov, AA; Ostretsova, IB | 2 |
| Berry, MN; Henly, DC | 1 |
| Conricode, KM; Ochs, RS | 1 |
| Wray, S | 1 |
| Hundal, HS; Kuret, CM; MacLennan, PA; Rennie, MJ; Watt, PW | 1 |
| Mason, MJ; Thomas, RC | 1 |
| Edlund, GL; Halestrap, AP | 1 |
| Rognstad, R | 2 |
| Jacobson, JJ; Prior, RL; Smith, SB | 1 |
| Halestrap, AP; Thomas, AP | 2 |
| Hall, AC; Wilkins, RJ | 1 |
| Hallows, KR; Knauf, PA; Restrepo, D | 1 |
| Crawford, RE; Gladden, LB; Hundal, HS; Watt, PW | 1 |
| Kenyon, E; la Cour, M; Lin, H; Miller, SS | 1 |
| Argilés, JM; Domènech, M; López-Soriano, FJ | 1 |
| Kuchel, PW; Xu, AS | 1 |
| Benz, AM; Izumi, Y; Katsuki, H; Zorumski, CF | 1 |
| Scofield, MA; Shimozono, M; Wangemann, P | 1 |
| Beaudry, M; el Abida, K; Mengual, R; Mouaffak, N; Rieu, M | 1 |
| Liu, J; Scofield, MA; Shimozono, M; Wangemann, P | 1 |
| Pösö, AR; Väihkönen, LK | 1 |
| Faelli, A; Gastaldi, G; Orsenigo, MN; Tosco, M | 1 |
| Grollman, EF; McPhie, P; Philp, NJ; Sauer, B; Ward, RD | 1 |
| Hajduch, E; Heyes, RR; Hundal, HS; Watt, PW | 1 |
| Brown, AM; Farrell, K; Fern, R; Ransom, BR; Swanson, RA; Wender, R | 1 |
| O'Regan, MH; Phillis, JW; Ren, J | 1 |
| Chih, CP; He, J; Roberts, EL; Sly, TS | 1 |
| Benham, CD; Cater, HL; Sundstrom, LE | 1 |
| Miller, JJ; Payne, RS; Rigor, BM; Schurr, A; Tseng, MT | 1 |
| Heinonen, OJ; Hyyppä, S; Nieminen, M; Pösö, AR; Väihkönen, LK | 1 |
| Gozal, D; Gozal, E; Payne, RS; Schurr, A; Tseng, MT | 1 |
| Bansal, N; Glickson, JD; Leeper, DB; Pickup, S; Zhou, R | 1 |
| Carey, A; Hopkins, IB; McKenna, MC | 1 |
| Miller, JJ; Payne, RS; Schurr, A; Tseng, MT | 1 |
| Emoto, A; Inuyama, M; Koyabu, N; Nakano, H; Ohtani, H; Satoh, S; Sawada, Y; Tsukimori, K; Ushigome, F | 1 |
| Bell, P; McClure, B; Meredith, D; Wilkins, R | 1 |
| Evans, RK; Gladden, LB; Schwartz, DD | 1 |
| Kageyama, K; Matsumura, A; Matsumura, K; Mizokawa, S; Murata, T; Nakamura, F; Ochi, H; Shigematsu, M; Tanaka, M; Watanabe, Y | 1 |
| Hayashi, T; Iida, H; Magata, Y; Miyake, Y; Murata, T; Ogawa, M; Teramoto, N; Watabe, H | 1 |
| Aman, RA; Damian, RT; Githui, EK | 1 |
| Cheeti, S; Lee, CH; Warrier, BK | 1 |
| Hayashi, H; Kawamata, K; Suzuki, Y | 1 |
| Colen, CB; Galloway, MP; Marples, B; Mathupala, SP; Seraji-Bozorgzad, N; Sloan, AE | 1 |
| Morris, ME; Wang, Q | 1 |
| Endo, T; Kimura, O; Tsukagoshi, K | 1 |
| Damon, TL; Erlichman, JS; Hart, M; Hewitt, A; Kurascz, J; Leiter, JC; Li, A | 1 |
| Hirasawa, M; Parsons, MP | 1 |
| Cui, W; Gao, D; Li, Q; Miao, DQ; Tan, JH; Wei, DL; Wu, YG; Zhou, P | 1 |
| Chen, G; Ebner, TJ; Gao, W; Peng, YP; Reinert, KC; Wang, X | 1 |
| Colen, CB; Francis, TB; Galloway, MP; Ghoddoussi, F; Koch, BJ; Mathupala, SP; Monterey, MD; Shen, Y; Sloan, AE; Yu, P | 1 |
| Baumann, M; Fabian, C; Kunz-Schughart, LA; Meyer, S; Mueller-Klieser, W; Sattler, UG; Yaromina, A; Zaleska, K; Zips, D | 1 |
| LeBlanc, PA; Rasco, JF; Rhodes, NR; Vincent, JB | 1 |
| Alessandri, B; Heimann, A; Kamada, Y; Kempski, O; Nagata, M; Schwandt, E | 1 |
| Kant, S; Kumar, A; Singh, SM | 1 |
| Buck, J; Choi, HB; Gordon, GR; Levin, LR; MacVicar, BA; Martinez, J; McLarnon, JG; Milner, TA; Rungta, RL; Ryu, JK; Tai, C; Tresguerres, M; Zhou, N | 1 |
| Howell, A; Lin, Z; Lisanti, MP; Martinez-Outschoorn, UE; Sotgia, F; Whitaker-Menezes, D | 1 |
| Brebner, K; Elustondo, PA; Hughes, ME; Kane, DA; Pavlov, E; White, AE | 1 |
| Guo, FC; Wang, LQ; Wang, YS; Zhang, J | 1 |
| Chan, O; Horblitt, A; Paranjape, SA; Sherwin, RS; Zhu, W | 1 |
| Chi, JT; Dewhirst, MW; Kennedy, KM; Landon, CD; Pizzo, S; Ribeiro, A; Richardson, R; Scarbrough, PM; Schroeder, T; Sonveaux, P; Yuan, H | 1 |
| Cambron, M; De Keyser, J; Demol, F; Kooijman, R; Laureys, G; Muscat, R; Valentino, M; Zammit, C | 1 |
| Angamo, EA; Heinemann, U; Kovács, R; Liotta, A; Rösner, J | 1 |
| Hatta, H; Hoshino, D; Kitaoka, Y; Masuda, H; Setogawa, S; Tamura, Y; Yanagihara, D | 1 |
| Liu, YF; Matsui, T; McEwen, BS; Omuro, H; Shima, T; Soya, H; Soya, M | 1 |
| Furugen, A; Futagi, Y; Ideno, M; Iseki, K; Kobayashi, M; Narumi, K; Sasaki, S | 1 |
| Guan, X; Morris, ME; Rodriguez-Cruz, V | 1 |
| Dasari, S; Gopala, S; Klaus, KA; Lanza, IR; Manjunatha, S; Nair, KS; Ruegsegger, GN; Summer, P; Vanderboom, PM; Zabeilski, P | 1 |
| Addison, A; Chan, O; Shah, M; Wang, P; Zhu, W | 1 |
| Gardner, RS; Gold, PE; Korol, DL; Tunur, T | 1 |
| Akhtar, MH; Gurudatt, NG; Hussain, KK; Park, DS; Seo, KD; Shim, YB | 1 |
| C Dias, P; Ferreira, V; Henrique, R; Jerónimo, C; Lameirinhas, A; Lobo, J; Macedo-Silva, C; Miranda-Gonçalves, V | 1 |
| Chao, Z; Li, Q; Lin, L; Meng, H; Tian, L; Wan, F; Wei, Z; Yu, J; Zhang, X | 1 |
77 other study(ies) available for lactic acid and alpha-cyano-4-hydroxycinnamate
| Article | Year |
|---|---|
Regulation of ATP sensitive potassium channel of isolated guinea pig ventricular myocytes by sarcolemmal monocarboxylate transport.
Topics: 2,4-Dinitrophenol; Acetates; Adenosine Triphosphate; Animals; Coumaric Acids; Cyanides; Dinitrophenols; Guinea Pigs; Heart Ventricles; Lactates; Lactic Acid; Membrane Potentials; Myocardium; Potassium Channels; Pyruvates; Pyruvic Acid; Sarcolemma | 1992 |
Lactate transport in insulin-secreting beta-cells: contrast between rat islets and HIT-T15 insulinoma cells.
Topics: 4-Chloromercuribenzenesulfonate; Amiloride; Animals; Biological Transport; Carrier Proteins; Cells, Cultured; Coumaric Acids; Hydrogen-Ion Concentration; Insulin; Insulin Secretion; Insulinoma; Islets of Langerhans; Lactates; Lactic Acid; Monocarboxylic Acid Transporters; Pancreatic Neoplasms; Quercetin; Rats; Tumor Cells, Cultured | 1992 |
Effects of inhibitors of gluconeogenesis on weak organic acid uptake in rat renal tubules.
Topics: Acetates; Animals; Carboxylic Acids; Citric Acid Cycle; Coumaric Acids; Fluorescein; Fluoresceins; Gluconeogenesis; Kidney Tubules, Proximal; Lactates; Lactic Acid; Malates; Male; Phenylpyruvic Acids; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar | 1992 |
Relationship between the stimulation of citric acid cycle oxidation and the stimulation of fatty acid esterification and inhibition of ketogenesis by lactate in isolated rat hepatocytes.
Topics: Animals; Citric Acid Cycle; Coumaric Acids; Esterification; Fatty Acids; Fluorocarbons; Gluconeogenesis; Ketone Bodies; Lactates; Lactic Acid; Liver; Male; Oxidation-Reduction; Palmitic Acid; Palmitic Acids; Propionates; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Succinates; Triglycerides | 1991 |
Vasopressin stimulates pyruvate utilization through a Ca(2+)-dependent mechanism and lactate formation by a protein kinase C-dependent mechanism in isolated rat hepatocytes.
Topics: Adenosine Triphosphate; Animals; Calcium; Cells, Cultured; Coumaric Acids; Epidermal Growth Factor; Fatty Acids; Glucose; Lactates; Lactic Acid; Liver; Protein Kinase C; Pyruvates; Pyruvic Acid; Rats; Type C Phospholipases; Vasopressins | 1991 |
The effects of metabolic inhibition on uterine metabolism and intracellular pH in the rat.
Topics: Animals; Antimetabolites; Coumaric Acids; Cyanides; Female; Glycolysis; Hydrogen-Ion Concentration; Iodoacetates; Iodoacetic Acid; Lactates; Lactic Acid; Oxidative Phosphorylation; Potassium; Pregnancy; Rats; Rats, Inbred Strains; Uterus | 1990 |
L(+)-lactate transport in perfused rat skeletal muscle: kinetic characteristics and sensitivity to pH and transport inhibitors.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; 4-Chloromercuribenzenesulfonate; Amiloride; Animals; Carrier Proteins; Cinnamates; Coumaric Acids; Female; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Monocarboxylic Acid Transporters; Muscles; Perfusion; Rats; Rats, Inbred Strains | 1988 |
A microelectrode study of the mechanisms of L-lactate entry into and release from frog sartorius muscle.
Topics: Animals; Anions; Coumaric Acids; Hydrogen-Ion Concentration; In Vitro Techniques; Lactates; Lactic Acid; Microelectrodes; Muscles; Rana temporaria; Time Factors | 1988 |
The kinetics of transport of lactate and pyruvate into rat hepatocytes. Evidence for the presence of a specific carrier similar to that in erythrocytes.
Topics: Animals; Antimetabolites; Biological Transport; Cell Separation; Coumaric Acids; Erythrocytes; Hydrogen-Ion Concentration; In Vitro Techniques; Intracellular Fluid; Lactates; Lactic Acid; Liver; Male; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains | 1988 |
The role of mitochondrial pyruvate transport in the control of lactate gluconeogenesis.
Topics: Animals; Bicarbonates; Biological Transport, Active; Coumaric Acids; Cytosol; Gluconeogenesis; In Vitro Techniques; Lactates; Lactic Acid; Mitochondria, Liver; Pyruvates; Pyruvic Acid; Rats | 1983 |
14CO2 fixation by phosphoenolpyruvate carboxykinase during gluconeogenesis in the intact rat liver cell.
Topics: Animals; Carbon Dioxide; Carbon Radioisotopes; Coumaric Acids; Gluconeogenesis; Glutamine; In Vitro Techniques; Lactates; Lactic Acid; Liver; Oxalates; Oxalic Acid; Phosphoenolpyruvate Carboxykinase (GTP); Rats | 1982 |
Metabolic pathways involved in lipogenesis from lactate and acetate in bovine adipose tissue: effects of metabolic inhibitors.
Topics: Acetates; Adipose Tissue; Aminooxyacetic Acid; Animals; Cattle; Cerulenin; Citrates; Citric Acid; Coumaric Acids; Fluoroacetates; Kynurenic Acid; Lactates; Lactic Acid; Lipids; Male; Malonates; Phenylpyruvic Acids | 1981 |
The rôle of mitochondrial pyruvate transport in the stimulation by glucagon and phenylephrine of gluconeogenesis from L-lactate in isolated rat hepatocytes.
Topics: Animals; Biological Transport; Coumaric Acids; Glucagon; Gluconeogenesis; In Vitro Techniques; Kinetics; Lactates; Lactic Acid; Liver; Male; Mitochondria, Liver; Phenylephrine; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Stimulation, Chemical | 1981 |
Computer stimulation of the effects of alpha-cyano-4-hydroxycinnamate on gluconeogenesis from L-lactate in rat liver cells.
Topics: Animals; Cinnamates; Computers; Coumaric Acids; Gluconeogenesis; In Vitro Techniques; Lactates; Lactic Acid; Liver; Male; Mitochondria, Liver; Models, Biological; Rats | 1981 |
Control of matrix synthesis in isolated bovine chondrocytes by extracellular and intracellular pH.
Topics: Animals; Cartilage; Cattle; Cells, Cultured; Coumaric Acids; Cytoplasm; Extracellular Matrix; Extracellular Space; Hydrochloric Acid; Hydrogen-Ion Concentration; In Vitro Techniques; Lactates; Lactic Acid; Proline; Sulfates | 1995 |
Control of intracellular pH during regulatory volume decrease in HL-60 cells.
Topics: Anions; Carrier Proteins; Chlorides; Coumaric Acids; Culture Media; Humans; Hydrogen-Ion Concentration; Intracellular Membranes; Ion Exchange; Lactates; Lactic Acid; Leukemia, Promyelocytic, Acute; Monocarboxylic Acid Transporters; Sodium-Hydrogen Exchangers; Tumor Cells, Cultured | 1994 |
Effects of flow and contraction on lactate transport in the perfused rat hindlimb.
Topics: Animals; Biological Transport; Coumaric Acids; Electric Stimulation; Female; Lactates; Lactic Acid; Muscle Contraction; Muscles; Perfusion; Phloretin; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar | 1994 |
Lactate transport in freshly isolated human fetal retinal pigment epithelium.
Topics: Basement Membrane; Biological Transport; Carrier Proteins; Coumaric Acids; Electrophysiology; Fetus; Fluoresceins; Humans; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Membrane Potentials; Mersalyl; Monocarboxylic Acid Transporters; Pigment Epithelium of Eye | 1994 |
Stimulatory effect of ethanol on weak organic acid uptake in rat renal tubules.
Topics: Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Animals; Biological Transport; Coumaric Acids; Cyanamide; Ethanol; Fluorescein; Fluoresceins; Gluconeogenesis; In Vitro Techniques; Kidney Tubules, Proximal; Lactates; Lactic Acid; Malates; Male; Phenylpyruvic Acids; Pyrazoles; Quinolinic Acid; Rats; Rats, Wistar | 1994 |
Alanine as a lipogenic precursor in isolated hepatocytes from obese Zucker rats.
Topics: Acetyl Coenzyme A; Alanine; Alanine Transaminase; Animals; Cells, Cultured; Citrates; Coumaric Acids; Fatty Acids; Glucose; Lactates; Lactic Acid; Leucine; Lipids; Liver; Liver Glycogen; Male; Mitochondria, Liver; Obesity; Pyruvates; Pyruvic Acid; Rats; Rats, Zucker | 1993 |
Characterisation of erythrocyte transmembrane exchange of trifluoroacetate using 19F-NMR: evidence for transport via the monocarboxylate transporter.
Topics: Animals; Anion Exchange Protein 1, Erythrocyte; Biological Transport; Cell Membrane Permeability; Coumaric Acids; Diffusion; Erythrocyte Membrane; Ethylmaleimide; Fluorides; Fluorine; Humans; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Phosphoric Acids; Pyruvates; Pyruvic Acid; Sheep; Trifluoroacetic Acid | 1993 |
Endogenous monocarboxylates sustain hippocampal synaptic function and morphological integrity during energy deprivation.
Topics: Animals; Biological Transport; Cell Communication; Coumaric Acids; Cytochalasin B; Electrophysiology; Energy Metabolism; Excitatory Postsynaptic Potentials; Glucose; Hippocampus; Iodoacetates; Iodoacetic Acid; Lactic Acid; Neuroglia; Neurons; Organ Culture Techniques; Pyruvic Acid; Rats; Rats, Inbred Strains; Synapses | 1997 |
Functional evidence for a monocarboxylate transporter (MCT) in strial marginal cells and molecular evidence for MCT1 and MCT2 in stria vascularis.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Base Sequence; Carrier Proteins; Coumaric Acids; Cricetinae; Cytosol; DNA, Complementary; Electrophoresis, Agar Gel; Gerbillinae; Hydrogen-Ion Concentration; Lactic Acid; Membrane Proteins; Molecular Sequence Data; Monocarboxylic Acid Transporters; Polymerase Chain Reaction; Pyruvic Acid; RNA; Sequence Homology, Nucleic Acid; Stria Vascularis | 1997 |
Lactate transport in L6 skeletal muscle cells and vesicles: allosteric or multisite mechanism and functional membrane marker of differentiation.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Allosteric Regulation; Animals; Biological Transport; Cell Line; Cell Membrane; Citric Acid; Coumaric Acids; Creatine Kinase; Kinetics; Lactic Acid; Muscle, Skeletal; Phenylmercury Compounds; Pyruvic Acid; Rats; Sarcolemma; Succinic Acid | 1998 |
Vestibular dark cells contain an H+/monocarboxylate- cotransporter in their apical and basolateral membrane.
Topics: 4-Chloromercuribenzenesulfonate; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acetates; Animals; Carrier Proteins; Cell Membrane; Coumaric Acids; Cricetinae; Dicarboxylic Acids; Electrophysiology; Gerbillinae; Hydrogen-Ion Concentration; Kinetics; Lactic Acid; Monocarboxylic Acid Transporters; Polymerase Chain Reaction; Pyruvic Acid; Vestibule, Labyrinth | 1998 |
Interindividual variation in total and carrier-mediated lactate influx into red blood cells.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Anion Exchange Protein 1, Erythrocyte; Carrier Proteins; Coumaric Acids; Erythrocytes; Female; Horses; Lactic Acid; Male; Monocarboxylic Acid Transporters; Sex Characteristics | 1998 |
An endogenous monocarboxylate transport in Xenopus laevis oocytes.
Topics: 1-Methyl-3-isobutylxanthine; 4-Chloromercuribenzenesulfonate; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Biological Transport; Carbon Radioisotopes; Carrier Proteins; Cations; Chlorine; Coumaric Acids; Female; Hydrogen-Ion Concentration; Lactic Acid; Oocytes; Pyruvic Acid; Radioisotopes; Sodium; Tetraethylammonium; Xenopus laevis | 2000 |
Determination of transport kinetics of chick MCT3 monocarboxylate transporter from retinal pigment epithelium by expression in genetically modified yeast.
Topics: 4-Chloromercuribenzenesulfonate; Animals; Biological Transport, Active; Carrier Proteins; Chickens; Coumaric Acids; Diethyl Pyrocarbonate; Fluorescent Dyes; Gene Expression Regulation, Fungal; Genetic Vectors; Green Fluorescent Proteins; Lactic Acid; Luminescent Proteins; Phloretin; Pigment Epithelium of Eye; Saccharomyces cerevisiae; Transformation, Genetic | 2000 |
Lactate transport in rat adipocytes: identification of monocarboxylate transporter 1 (MCT1) and its modulation during streptozotocin-induced diabetes.
Topics: Adipocytes; Animals; Biological Transport; Blotting, Western; Brain; Carrier Proteins; Cell Membrane; Cells, Cultured; Coumaric Acids; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Down-Regulation; Glucose Transporter Type 4; Glucose Transporter Type 5; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Liver; Male; Monocarboxylic Acid Transporters; Monosaccharide Transport Proteins; Muscle Proteins; Rats; Rats, Sprague-Dawley; Time Factors | 2000 |
Astrocytic glycogen influences axon function and survival during glucose deprivation in central white matter.
Topics: 4-Chloromercuribenzenesulfonate; Action Potentials; Animals; Astrocytes; Axons; Biological Transport; Cell Survival; Coumaric Acids; Culture Media; Enzyme Inhibitors; Glucose; Glycogen; In Vitro Techniques; Lactic Acid; Optic Nerve; Quercetin; Rats; Rats, Long-Evans; Reaction Time | 2000 |
Studies on the effects of lactate transport inhibition, pyruvate, glucose and glutamine on amino acid, lactate and glucose release from the ischemic rat cerebral cortex.
Topics: Amino Acids; Animals; Biological Transport; Brain Ischemia; Cerebral Cortex; Coumaric Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Energy Metabolism; Ethanolamines; gamma-Aminobutyric Acid; Glucose; Glutamine; Lactic Acid; Male; Pyruvic Acid; Quercetin; Rats; Rats, Sprague-Dawley | 2001 |
Comparison of glucose and lactate as substrates during NMDA-induced activation of hippocampal slices.
Topics: Animals; Biological Transport; Cell Hypoxia; Coumaric Acids; Dose-Response Relationship, Drug; Energy Metabolism; Glucose; Hippocampus; Hydrogen-Ion Concentration; Hypoxia, Brain; In Vitro Techniques; Intracellular Fluid; Lactic Acid; Male; N-Methylaspartate; Neurons; Potassium; Rats; Rats, Inbred F344; Synaptic Transmission | 2001 |
Neuroprotective role of monocarboxylate transport during glucose deprivation in slice cultures of rat hippocampus.
Topics: Action Potentials; Animals; Anion Transport Proteins; Carrier Proteins; Cell Survival; Coumaric Acids; Deoxyglucose; Drug Combinations; Electrophysiology; Energy Metabolism; Glucose; Hippocampus; In Vitro Techniques; Lactic Acid; Neuroglia; Neurons; Rats; Rats, Wistar | 2001 |
Blockade of lactate transport exacerbates delayed neuronal damage in a rat model of cerebral ischemia.
Topics: Animals; Blood-Brain Barrier; Brain Ischemia; Carrier Proteins; Coumaric Acids; Energy Metabolism; Hippocampus; Lactic Acid; Male; Monocarboxylic Acid Transporters; Nerve Degeneration; Neurons; Rats; Rats, Sprague-Dawley | 2001 |
Lactate-transport activity in RBCs of trained and untrained individuals from four racing species.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adolescent; Adult; Animals; Anion Exchange Protein 1, Erythrocyte; Biological Transport; Carrier Proteins; Coumaric Acids; Deer; Dogs; Erythrocytes; Female; Horses; Humans; Lactic Acid; Male; Middle Aged; Monocarboxylic Acid Transporters; Physical Exertion; Running; Species Specificity | 2001 |
Excitotoxic preconditioning elicited by both glutamate and hypoxia and abolished by lactate transport inhibition in rat hippocampal slices.
Topics: Action Potentials; Animals; Carrier Proteins; Coumaric Acids; Excitatory Amino Acid Agonists; Glutamic Acid; Hippocampus; Hypoxia-Ischemia, Brain; Ischemic Preconditioning; Lactic Acid; Male; N-Methylaspartate; Neurons; Neurotoxins; Organ Culture Techniques; Rats; Rats, Sprague-Dawley | 2001 |
Enhancement of hyperglycemia-induced acidification of human melanoma xenografts with inhibitors of respiration and ion transport.
Topics: 3-Iodobenzylguanidine; Animals; Cell Respiration; Coumaric Acids; Glycolysis; Humans; Hydrogen-Ion Concentration; Hyperglycemia; Ion Transport; Lactic Acid; Magnetic Resonance Spectroscopy; Melanoma; Mice; Neoplasm Transplantation | 2001 |
Alpha-cyano-4-hydroxycinnamate decreases both glucose and lactate metabolism in neurons and astrocytes: implications for lactate as an energy substrate for neurons.
Topics: Animals; Astrocytes; Brain; Carbon Dioxide; Carbon Radioisotopes; Cells, Cultured; Coumaric Acids; Dose-Response Relationship, Drug; Down-Regulation; Female; Fetus; Glucose; Lactic Acid; Monosaccharide Transport Proteins; Neurons; Oxidative Phosphorylation; Pregnancy; Pyruvic Acid; Rats | 2001 |
Preischemic hyperglycemia-aggravated damage: evidence that lactate utilization is beneficial and glucose-induced corticosterone release is detrimental.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Animals; Blood Glucose; Brain Ischemia; Corticosterone; Coumaric Acids; Cyclic AMP; Electric Stimulation; Enzyme Inhibitors; Glucose; Heart Arrest, Induced; Hippocampus; Hyperglycemia; Lactic Acid; Male; Metyrapone; Nerve Degeneration; Organ Culture Techniques; Rats; Rats, Sprague-Dawley; Recovery of Function; Reperfusion Injury | 2001 |
Characteristics of L-lactic acid transport in basal membrane vesicles of human placental syncytiotrophoblast.
Topics: 4-Chloromercuribenzenesulfonate; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Biological Transport, Active; Carbon Radioisotopes; Carboxylic Acids; Cell Membrane; Cell Separation; Coumaric Acids; Enzyme Inhibitors; Female; Humans; Hydrogen-Ion Concentration; Kinetics; Lactic Acid; Microvilli; Monocarboxylic Acid Transporters; Phloretin; Placenta; Sodium; Subcellular Fractions; Trophoblasts | 2002 |
Functional and molecular characterisation of lactic acid transport in bovine articular chondrocytes.
Topics: Animals; Biological Transport; Carrier Proteins; Cartilage; Cattle; Cells, Cultured; Chondrocytes; Coumaric Acids; Hydrogen-Ion Concentration; Kinetics; Lactic Acid; Monocarboxylic Acid Transporters; Phloretin; Protein Isoforms | 2002 |
Effect of myocardial volume overload and heart failure on lactate transport into isolated cardiac myocytes.
Topics: Animals; Biological Transport, Active; Blotting, Western; Body Weight; Buffers; Butyrates; Cell Separation; Coumaric Acids; Electrophoresis, Polyacrylamide Gel; Heart; Heart Failure; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Lactic Acid; Male; Monocarboxylic Acid Transporters; Muscle Cells; Myocardium; Organ Size; Rats; Rats, Sprague-Dawley | 2003 |
Role of lactate in the brain energy metabolism: revealed by Bioradiography.
Topics: Animals; Brain; Coumaric Acids; Dose-Response Relationship, Drug; Energy Metabolism; Fluorodeoxyglucose F18; Glucose; In Vitro Techniques; Lactic Acid; Male; Radiography; Rats; Rats, Sprague-Dawley; Time Factors | 2004 |
Understanding of cerebral energy metabolism by dynamic living brain slice imaging system with [18F]FDG.
Topics: Animals; Autoradiography; Cerebral Cortex; Coumaric Acids; Diagnostic Imaging; Drug Interactions; Energy Metabolism; Fluorodeoxyglucose F18; Glucose; Image Processing, Computer-Assisted; In Vitro Techniques; Lactic Acid; Male; Potassium Chloride; Radionuclide Imaging; Radiopharmaceuticals; Rats; Rats, Wistar; Time Factors | 2005 |
Schistosoma mansoni: biochemical characterization of lactate transporters or similar proteins.
Topics: Animals; Biomphalaria; Coumaric Acids; Lactic Acid; Mice; Monocarboxylic Acid Transporters; Papio; Phloretin; Probenecid; Schistosoma mansoni | 2006 |
The role of monocarboxylate transporters in uptake of lactic acid in HeLa cells.
Topics: Biological Transport; Butyric Acid; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Survival; Coumaric Acids; Dose-Response Relationship, Drug; HeLa Cells; Humans; Hydrogen-Ion Concentration; Ionophores; Lactic Acid; Monocarboxylic Acid Transporters; Nicotinic Acids; p-Chloromercuribenzoic Acid; Protein Isoforms; Reverse Transcriptase Polymerase Chain Reaction | 2006 |
Propionate absorption associated with bicarbonate secretion in vitro in the mouse cecum.
Topics: Acetazolamide; Animals; Bicarbonates; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Cecum; Coumaric Acids; Electrophysiology; Hydrogen-Ion Concentration; In Vitro Techniques; Intestinal Absorption; Intestinal Mucosa; Lactic Acid; Membrane Potentials; Mice; Mice, Inbred Strains; Monocarboxylic Acid Transporters; Propionates; Symporters | 2007 |
Metabolic remodeling of malignant gliomas for enhanced sensitization during radiotherapy: an in vitro study.
Topics: Adaptation, Physiological; Apoptosis; Cell Line, Tumor; Cell Survival; Coumaric Acids; Dose-Response Relationship, Drug; Glioma; Humans; Lactic Acid; Neoplasm Proteins; Radiation Tolerance; Radiation-Sensitizing Agents; Signal Transduction | 2006 |
The role of monocarboxylate transporter 2 and 4 in the transport of gamma-hydroxybutyric acid in mammalian cells.
Topics: Biological Transport; Blotting, Western; Cell Line, Tumor; Coumaric Acids; Dose-Response Relationship, Drug; Gene Expression; Humans; Hydrogen-Ion Concentration; Hydroxybutyrates; Kinetics; Lactic Acid; Monocarboxylic Acid Transporters; Muscle Proteins; p-Chloromercuribenzoic Acid; Phloretin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Sodium | 2007 |
Uptake of 4-chloro-2-methylphenoxyacetic acid (MCPA) from the apical membrane of Caco-2 cells by the monocarboxylic acid transporter.
Topics: 2-Methyl-4-chlorophenoxyacetic Acid; 2,4-Dinitrophenol; Benzoic Acid; Biological Transport; Caco-2 Cells; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Membrane; Cold Temperature; Coumaric Acids; Herbicides; Humans; Hydrogen-Ion Concentration; Lactic Acid; Monocarboxylic Acid Transporters; Sodium Azide | 2008 |
Inhibition of monocarboxylate transporter 2 in the retrotrapezoid nucleus in rats: a test of the astrocyte-neuron lactate-shuttle hypothesis.
Topics: 4-Chloro-7-nitrobenzofurazan; Animals; Astrocytes; Chemoreceptor Cells; Coumaric Acids; Deoxyglucose; Extracellular Fluid; Female; Hydrogen-Ion Concentration; In Vitro Techniques; Intracellular Membranes; Lactic Acid; Male; Medulla Oblongata; Models, Neurological; Monocarboxylic Acid Transporters; Neurons; Rats; Rats, Sprague-Dawley; Respiration | 2008 |
ATP-sensitive potassium channel-mediated lactate effect on orexin neurons: implications for brain energetics during arousal.
Topics: Animals; Astrocytes; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Coumaric Acids; Dose-Response Relationship, Drug; Fluoroacetates; Gene Expression; Glucose; Glyburide; Hypoglycemic Agents; Hypothalamus; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Ionophores; KATP Channels; Lactic Acid; Membrane Potentials; Mice; Mice, Inbred C57BL; Neurons; Neuropeptides; Orexins; Patch-Clamp Techniques; Sodium Channel Blockers; Tetrodotoxin | 2010 |
Glucose metabolism in mouse cumulus cells prevents oocyte aging by maintaining both energy supply and the intracellular redox potential.
Topics: Animals; Cellular Senescence; Coumaric Acids; Cumulus Cells; Energy Metabolism; Female; Glucose; Lactic Acid; Mice; Oocytes; Organic Chemicals; Oxidation-Reduction; Pyruvic Acid; Rotenone | 2011 |
Cellular and metabolic origins of flavoprotein autofluorescence in the cerebellar cortex in vivo.
Topics: Animals; Aspartic Acid; Brain Mapping; Cerebellar Cortex; Coumaric Acids; Dose-Response Relationship, Drug; Electric Stimulation; Evoked Potentials; Excitatory Amino Acid Antagonists; Flavoproteins; In Vitro Techniques; Lactic Acid; Mice; Microscopy, Fluorescence; Neuroglia; Neurons | 2011 |
Metabolic targeting of lactate efflux by malignant glioma inhibits invasiveness and induces necrosis: an in vivo study.
Topics: Animals; Antineoplastic Agents; Biological Transport; Brain Neoplasms; Cell Line, Tumor; Coumaric Acids; Disease Models, Animal; Down-Regulation; Glioma; Humans; Lactic Acid; Male; Molecular Targeted Therapy; Necrosis; Neoplasm Invasiveness; Rats; Rats, Nude; Transplantation, Heterologous; Up-Regulation; Xenograft Model Antitumor Assays | 2011 |
Effects of three modifiers of glycolysis on ATP, lactate, hypoxia, and growth in human tumor cell lines in vivo.
Topics: Adenosine Triphosphate; Animals; Cell Line, Tumor; Cell Proliferation; Coumaric Acids; Dichloroacetic Acid; Enzyme Inhibitors; Female; Gene Expression Regulation, Neoplastic; Glycolysis; Humans; Hydrogen-Ion Concentration; Lactic Acid; Mice; Oxamic Acid; Oxygen Consumption; Transplantation, Heterologous | 2012 |
Monocarboxylate transporters are not responsible for Cr(3+) transport from endosomes.
Topics: Animals; Biological Transport; Cell Line; Chromium; Coumaric Acids; Endocytosis; Endosomes; Lactic Acid; Mice; Monocarboxylic Acid Transporters; Transferrin | 2012 |
The neuroprotective effect of lactate is not due to improved glutamate uptake after controlled cortical impact in rats.
Topics: Animals; Brain Chemistry; Brain Injuries; Cerebral Cortex; Cerebrovascular Circulation; Chromatography, High Pressure Liquid; Coumaric Acids; Extracellular Space; Glutamic Acid; Lactic Acid; Male; Microdialysis; Neuroprotective Agents; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Skull Fractures; Stereotaxic Techniques | 2012 |
α-Cyano-4-hydroxycinnamate induces apoptosis in Dalton's lymphoma cells: role of altered cell survival-regulatory mechanisms.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle Proteins; Cell Survival; Coumaric Acids; Glucose; Interferon-gamma; Interleukin-10; Interleukin-6; Lactic Acid; Lymphoma, T-Cell; Male; Mice; Mice, Inbred BALB C; Nitric Oxide; Oncogene Proteins; Thymocytes; Tumor Cells, Cultured | 2013 |
Metabolic communication between astrocytes and neurons via bicarbonate-responsive soluble adenylyl cyclase.
Topics: 1-Methyl-3-isobutylxanthine; 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenylyl Cyclases; Animals; Animals, Newborn; Astrocytes; Bicarbonates; Coumaric Acids; Cyclic AMP; Dose-Response Relationship, Drug; Excitatory Postsynaptic Potentials; Glial Fibrillary Acidic Protein; Glucose; Glycogen; Green Fluorescent Proteins; Hippocampus; In Vitro Techniques; Lactic Acid; Microscopy, Immunoelectron; Microtubule-Associated Proteins; Models, Biological; Monocarboxylic Acid Transporters; Neurons; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Potassium; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Tetrodotoxin | 2012 |
Ketone bodies and two-compartment tumor metabolism: stromal ketone production fuels mitochondrial biogenesis in epithelial cancer cells.
Topics: Acetyl-CoA C-Acetyltransferase; Breast Neoplasms; Caveolin 1; Cell Line; Chaperonin 60; Coculture Techniques; Coumaric Acids; Down-Regulation; Epithelial Cells; Female; Humans; Ketone Bodies; Lactic Acid; MCF-7 Cells; Mitochondria; Mitochondrial Turnover; Monocarboxylic Acid Transporters; RNA Interference; RNA, Small Interfering; Smad2 Protein; Smad3 Protein; Symporters | 2012 |
Physical and functional association of lactate dehydrogenase (LDH) with skeletal muscle mitochondria.
Topics: Animals; Biological Transport, Active; Coumaric Acids; L-Lactate Dehydrogenase; Lactic Acid; Mitochondria, Muscle; Mitochondrial Membranes; Muscle Proteins; Muscle, Skeletal; Oxidation-Reduction; Oxygen Consumption; Pyruvic Acid; Rats; Rats, Sprague-Dawley | 2013 |
[Study on the anti-Lewis lung carcinoma effect of metformin combined with MCT1 inhibitor CHC].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Lewis Lung; Coumaric Acids; Female; Lactic Acid; Lung Neoplasms; Metformin; Mice; Mice, Inbred C57BL; Monocarboxylic Acid Transporters; Symporters; Tumor Cells, Cultured | 2013 |
Lactate-induced release of GABA in the ventromedial hypothalamus contributes to counterregulatory failure in recurrent hypoglycemia and diabetes.
Topics: Animals; Bicuculline; Coumaric Acids; Diabetes Mellitus, Experimental; Diazoxide; GABA Antagonists; gamma-Aminobutyric Acid; Hypoglycemia; Insulin; Lactic Acid; Male; Microdialysis; Oxamic Acid; Rats; Rats, Sprague-Dawley; Ventromedial Hypothalamic Nucleus | 2013 |
Catabolism of exogenous lactate reveals it as a legitimate metabolic substrate in breast cancer.
Topics: Adult; Aged; Alanine; Animals; Breast Neoplasms; Cell Death; Cell Hypoxia; Cell Line, Tumor; Coumaric Acids; Disease Models, Animal; Female; Glucose; Glutamic Acid; Humans; Kinetics; Lactic Acid; Metabolic Networks and Pathways; Metabolomics; Middle Aged; Neoplasm Staging; Rats | 2013 |
β₂-adrenergic receptors protect axons during energetic stress but do not influence basal glio-axonal lactate shuttling in mouse white matter.
Topics: Adrenergic beta-2 Receptor Agonists; Adrenergic beta-2 Receptor Antagonists; Animals; Axons; Central Nervous System Agents; Cerebellum; Clenbuterol; Corpus Callosum; Coumaric Acids; Glutamic Acid; Lactic Acid; Male; Mice, Inbred C57BL; Neuroglia; Propanolamines; Receptors, Adrenergic, beta-2; Stress, Physiological; White Matter | 2014 |
A neuronal lactate uptake inhibitor slows recovery of extracellular ion concentration changes in the hippocampal CA3 region by affecting energy metabolism.
Topics: Animals; CA3 Region, Hippocampal; Coumaric Acids; Energy Metabolism; Extracellular Fluid; Hydroxybenzoates; Lactic Acid; Male; Neurons; Organ Culture Techniques; Rats; Rats, Wistar; Resorcinols | 2016 |
Exercise-induced expression of monocarboxylate transporter 2 in the cerebellum and its contribution to motor performance.
Topics: Animals; Biological Transport; Cerebellum; Cerebral Cortex; Coumaric Acids; Lactic Acid; Male; Mice, Inbred ICR; Monocarboxylic Acid Transporters; Motor Activity; Physical Conditioning, Animal; RNA, Messenger; Symporters | 2016 |
Astrocytic glycogen-derived lactate fuels the brain during exhaustive exercise to maintain endurance capacity.
Topics: Adenosine Triphosphate; Animals; Astrocytes; Brain; Coumaric Acids; Energy Metabolism; Fatigue; Glycogen; Glycogenolysis; Lactic Acid; Male; Metabolomics; Monocarboxylic Acid Transporters; Muscle, Skeletal; Physical Exertion; Rats; Rats, Wistar | 2017 |
Involvement of monocarboxylate transporter 1 (SLC16A1) in the uptake of l-lactate in human astrocytes.
Topics: Astrocytes; Biological Transport, Active; Cell Line; Coumaric Acids; Dose-Response Relationship, Drug; Humans; Hydrogen-Ion Concentration; Kinetics; Lactic Acid; Monocarboxylic Acid Transporters; Pyrrolidonecarboxylic Acid; Symporters | 2018 |
Cellular Uptake of MCT1 Inhibitors AR-C155858 and AZD3965 and Their Effects on MCT-Mediated Transport of L-Lactate in Murine 4T1 Breast Tumor Cancer Cells.
Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Coumaric Acids; Drug Screening Assays, Antitumor; Female; Humans; Hydrogen-Ion Concentration; Lactic Acid; Mice; Monocarboxylic Acid Transporters; Pyrimidinones; Symporters; Thiophenes; Uracil | 2019 |
Insulin deficiency and intranasal insulin alter brain mitochondrial function: a potential factor for dementia in diabetes.
Topics: Adenosine Triphosphate; Administration, Intranasal; Animals; Brain; Coumaric Acids; Dementia; Diabetes Mellitus, Experimental; Drug Implants; Energy Metabolism; Homeostasis; Insulin; Ketones; Lactic Acid; Male; Mice; Mice, Inbred C57BL; Mitochondria; Monocarboxylic Acid Transporters; Nerve Tissue Proteins; Oxidative Stress; Phosphorylation; Protein Processing, Post-Translational; Reactive Oxygen Species | 2019 |
Recurrent glucose deprivation leads to the preferential use of lactate by neurons in the ventromedial hypothalamus.
Topics: Animals; Carbon Radioisotopes; Catecholamines; Coumaric Acids; gamma-Aminobutyric Acid; Glucose; Glucose Clamp Technique; Hypoglycemia; Hypothalamus, Middle; Lactic Acid; Microdialysis; Monocarboxylic Acid Transporters; Neurons; Rats; RNA, Messenger | 2019 |
Involvement of lactate transport in two object recognition tasks that require either the hippocampus or striatum.
Topics: Animals; Corpus Striatum; Coumaric Acids; Hippocampus; Lactic Acid; Male; Monocarboxylic Acid Transporters; Rats, Long-Evans; Recognition, Psychology; Space Perception; Visual Perception | 2019 |
Nano-biosensor for the in vitro lactate detection using bi-functionalized conducting polymer/N, S-doped carbon; the effect of αCHC inhibitor on lactate level in cancer cell lines.
Topics: Animals; Biosensing Techniques; Carbon; Cell Line, Tumor; Coumaric Acids; Electrochemical Techniques; Enzymes, Immobilized; Humans; L-Lactate Dehydrogenase; Lactic Acid; Molecular Probes; Nanotechnology; Polymers; Reproducibility of Results | 2020 |
Lactate Increases Renal Cell Carcinoma Aggressiveness through Sirtuin 1-Dependent Epithelial Mesenchymal Transition Axis Regulation.
Topics: Acetylation; Animals; Biological Transport; Cadherins; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Movement; Chickens; Coumaric Acids; Culture Media, Conditioned; Down-Regulation; Epigenesis, Genetic; Epithelial-Mesenchymal Transition; Histones; Humans; Kidney; Kidney Neoplasms; Lactic Acid; Monocarboxylic Acid Transporters; Neoplasm Invasiveness; Niacinamide; Signal Transduction; Sirtuin 1; Smad4 Protein | 2020 |
Advanced Cancer Starvation Therapy by Simultaneous Deprivation of Lactate and Glucose Using a MOF Nanoplatform.
Topics: Animals; Cell Survival; Coumaric Acids; Glucose; Glucose Oxidase; Imidazoles; Lactic Acid; Metal-Organic Frameworks; Mice; Nanomedicine; Nanoparticles; Neoplasms | 2021 |