lactic acid has been researched along with adenosine in 173 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 41 (23.70) | 18.7374 |
| 1990's | 72 (41.62) | 18.2507 |
| 2000's | 39 (22.54) | 29.6817 |
| 2010's | 14 (8.09) | 24.3611 |
| 2020's | 7 (4.05) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Blancas-Torres, PG; Castrejon-Sosa, M; Gutierrez-Juarez, R; Madrid-Marina, V; Martinez-Valdez, H; Piña, E | 1 |
| Baier, H; Brendel, W; Christ, M; Conzen, PF; Goetz, AE; Habazettl, H; Peter, K; Vollmar, B | 1 |
| Chiasson, JL; Coderre, L; Srivastava, AK | 1 |
| Ballard, HJ | 1 |
| Bistrian, BR; Blackburn, GL; Fechner, KD; Palombo, JD; Pomposelli, JJ | 1 |
| Anselone, CG; Bristow, DJ; McFalls, EO; Pantely, GA | 1 |
| Dobson, JG; Fenton, RA; Romano, FD | 1 |
| McKenzie, JE; Schwartz, LM | 1 |
| Hillered, L; Nilsson, P; Pontén, U; Ungerstedt, U | 1 |
| el Khelly, F; Hudlická, O | 1 |
| Barclay, JK; Burton, HW | 1 |
| Blaise, G; Boulanger, Y; Cardoso, M; Gougoux, A; Léveillé, M; Noël, J; Prud'homme, M; Vinay, P; Vinet, B | 1 |
| Ghani, QP; Hunt, TK; Hussain, MZ | 1 |
| Bistrian, BR; Blackburn, GL; Hirschberg, Y; Palombo, JD; Pomposelli, JJ | 1 |
| Downey, HF; Kim, SJ; Murakami, H | 1 |
| Abiko, Y; Haneda, T; Ichihara, K; Onodera, S | 1 |
| Carlsson, S; Hagberg, H; Sandberg, M; Skarphedinsson, JO; Thorén, P | 1 |
| Buc, HA; Claeyssens, S; Lavoinne, A; Matray, F; Pinosa, M | 1 |
| Palmer, GC | 1 |
| Hori, M; Inoue, M; Iwai, K; Iwakura, K; Kagiya, T; Kamada, T; Kitabatake, A; Kitakaze, M; Koretsune, Y; Tamai, J | 1 |
| Mukerji, S; Walz, W | 1 |
| Hue, L; Rider, MH | 1 |
| Challiss, RA; Dimitriadis, GD; Leighton, B; Newsholme, EA; Parry-Billings, M; Vlachonikolis, IG; West, D | 1 |
| Kaufman, MP; Rotto, DM | 1 |
| Fuller, SJ; Sugden, PH | 1 |
| Carroll, MJ; Young, M | 1 |
| Anselone, CG; Bristow, JD; McFalls, EO; Pantely, GA | 1 |
| Gewirtz, H; Most, AS; Olsson, RA | 1 |
| Kao, RL; Magovern, GJ | 1 |
| Budohoski, L; Challiss, RA; Lozeman, FJ; McManus, B; Newsholme, EA | 1 |
| Budohoski, L; Challiss, RA; McManus, B; Newsholme, EA | 1 |
| Arentzen, CE; Bache, RJ; Simon, AB; Vrobel, TR | 1 |
| Bockman, EL; McKenzie, JE | 1 |
| Challiss, RA; Espinal, J; Newsholme, EA | 1 |
| Bray, PG; Howells, RE; Mendis, AM | 1 |
| James, T; Parmley, WW; Sievers, R; Wikman-Coffelt, J | 1 |
| Fredholm, B; Hohlbach, G; Schildberg, FW; Schoenberg, M | 1 |
| Crul, JF; de Bruyn, CH; Gielen, MJ; Oerlemans, FT; van Bennekom, CA; Verburg, MP | 1 |
| Bonifacj, JF; Laborit, H | 1 |
| Berne, RM; Rubio, R; Winn, HR | 1 |
| Brautigan, DL; Brown, P; Gewirtz, H; Most, AS; Olsson, RA | 1 |
| Barry, DN | 1 |
| Apstein, CS; Vogel, WM | 1 |
| Haddy, FJ; McKenzie, JE; Steffen, RP | 1 |
| Bache, RJ; Jorgensen, CR; Vrobel, TR | 1 |
| Erecińska, M; Nishiki, K; Nuutinen, EM; Wilson, DF | 1 |
| Deaciuc, IV; Ilonca, A | 1 |
| de Jong, JW; Harmsen, E; Serruys, PW | 1 |
| Hall, JL; Hamilton, CD; Pizzurro, RD; Reiling, CM; Stanley, WC; Van Wylen, DG | 1 |
| Chujo, M; Hori, M; Inoue, M; Kitakaze, M; Minamino, T; Mori, H; Morioka, T; Node, K; Shinozaki, Y; Takeda, H | 1 |
| Downey, HF; Fan, WL; Gao, ZP; Mallet, RT | 1 |
| Maripu, E; Nilsson, S; Ronquist, G; Waldenström, A; Wikström, G | 1 |
| Engelstein, ED; Lerman, BB | 1 |
| Neild, GH; Patel, VC; Woolfson, RG; Yellon, DM | 1 |
| Buffington, CW; Watanabe, S | 1 |
| Hogan, MC; Kurdak, SS; Wagner, PD | 1 |
| Hammon, JW; Hudspeth, DA; McGee, DS; Nakanishi, K; Sato, H; Van Wylen, DG; Vinten-Johansen, J; Williams, MW; Zhao, ZQ | 1 |
| Brurok, H; Holten, T; Jynge, P; Schjøtt, J | 1 |
| Bardenheuer, HJ; Fabry, A; Höfling, B; Peter, K | 1 |
| Chagoya de Sánchez, V; Díaz-Muñoz, M; Hernández-Muñoz, R | 1 |
| Mikhailidis, DP; Strong, P; Thompson, CS | 1 |
| Baier, H; Christ, M; Conzen, PF; Habazettl, H; Peter, K; Vollmar, B | 1 |
| Henriksson, J; Jorfeldt, L; Rosdahl, H; Ungerstedt, U | 1 |
| Delyani, JA; Van Wylen, DG | 1 |
| Van Wylen, DG | 1 |
| Downey, HF; Van Wylen, DG; Williams, AG | 1 |
| Asimakis, GK; Conti, VR; Inners-McBride, K | 1 |
| Achike, FI; Ballard, HJ | 1 |
| Anderson, R; Coates, J; Ellis, F; Evans, B; Gurden, MF; Johnstone, J; Kennedy, I; Martin, DP; Strong, P | 1 |
| Gutierrez-Juárez, R; Madrid-Marina, V; Piña, E | 1 |
| Fowler, JC | 1 |
| Clanachan, AS; Coulson, CS; Finegan, BA; Lopaschuk, GD | 1 |
| Hori, M; Inoue, M; Kamada, T; Kitakaze, M; Sato, H; Takashima, S | 1 |
| Lasley, RD; Mentzer, RM | 1 |
| Kaloyianni, M; Michaelidis, B; Moutou, K | 1 |
| Beresewicz, A; Cedro-Ceremuåzyńska, K; Karwatowska-Prokopczuk, E; Lewartowski, B | 1 |
| Matsunaga, T; Okumura, K; Tabuchi, T; Tayama, S; Tsunoda, R; Yasue, H | 1 |
| Inobe, Y; Kawano, H; Kojima, A; Kugiyama, K; Morita, E; Okumura, K; Takahashi, M; Tomiguchi, S; Tsuji, A; Yasue, H | 1 |
| Downey, HF; Lee, SC; Mallet, RT | 1 |
| Bernocchi, P; Bregu, R; Cevese, A; Motta, A; Poltronieri, R; Zancanaro, C | 1 |
| Kolb, J; Peters, U; Scheller, D; Tegtmeier, F | 1 |
| Korchazhkina, OV; Pisarenko, OI; Serebryakova, LI; Studneva, IM; Tskitishvily, OV | 1 |
| Dybdahl, A; Gribbestad, IS; Midelfart, A | 1 |
| Ballard, HJ; Mo, FM | 2 |
| Downey, HF; Gao, ZP; He, MX; Mallet, RT; Sun, J | 1 |
| Beller, GA; Camarano, G; Ellis, M; Feldman, MD; Fenster, MS; Johnson, WH; Linden, J | 1 |
| Wikström, BG | 1 |
| Kovács, P; Nosztray, K; Szabó, JZ; Szegi, J; Szentmiklósi, AJ; Ujfalusi, A; Varga, E | 1 |
| Askenasy, N; Navon, G | 1 |
| Kubonoya, K; Power, GG | 1 |
| Burns, W; Collins, G; Esquivel, CO; Garcia-Kennedy, R; Hayashi, M; Tojimbara, T; Wicomb, WN | 1 |
| Bell, MJ; Carcillo, JA; Clark, RS; Jackson, EK; Kochanek, PM; Marion, DW; Mi, Z; Obrist, WD; Wisneiwski, SR | 1 |
| Dahmann, R; Decking, UK; Dolu, B; Kelm, M; Perings, S; Schäfer, S; Schrader, J; Strauer, BE | 1 |
| Asanuma, H; Funaya, H; Hori, M; Kitakaze, M; Kuzuya, T; Minamino, T; Sato, H; Ueda, Y | 1 |
| Dutkowski, P; Junginger, T; Southard, JH | 1 |
| Ebihara, Y; Hasegawa, H; Shinmura, K; Suganuma, Y; Takayama, M; Tamaki, K; Tani, M | 1 |
| Dahms, TE; Pearse, DB; Wagner, EM | 1 |
| Inobe, Y; Kugiyama, K; Morita, E; Motoyama, T; Ogawa, H; Ohgushi, M; Yasue, H | 1 |
| Browning, MJ; Hohl, CM; Jurkowitz, MS; Litsky, ML | 1 |
| Araki, T; Kubonoya, K; Power, GG; Sawa, R; Yoneyama, Y | 1 |
| Earm, YE; Ho, WK; Lee, SH | 1 |
| Carretier, M; Eugene, M; Goujon, JM; Hauet, T; Tallineau, C; Tillement, JP | 1 |
| de Geest, H; Dubiel, J; Dudek, D; Flameng, W; Grodecki, J; Kocurek, A; Pieniazek, P; Trebacz, J; Zmudka, K | 1 |
| Deussen, A; Loncar, R | 1 |
| Beck, B; Burlet, C; Devaux, Y; Halejcio-Delophont, P; Mertes, PM; Richoux, JP; Siaghy, EM; Ungureanu-Longrois, D; Villemot, JP | 1 |
| Matsuda, H; Matsuoka, J; Tanaka, N; Yagi, T; Yamamura, H | 1 |
| Han, C; Lautt, WW; Ming, Z | 1 |
| Feigl, EO; Kroll, K; Richmond, KN; Van Bibber, R; Yada, T | 1 |
| Borger, MA; Cohen, G; Li, RK; Merante, F; Mickle, DA; Mohabeer, MK; Rao, V; Shirai, T; Tumiati, LC; Weisel, RD | 1 |
| Bardenheuer, HJ; Eckstein, HH; Martin, E; Michel, A; Weigand, MA | 1 |
| Carrier, M; Pelletier, LC; Trudel, S | 1 |
| Ballog, R; Biaggioni, I; Costa, F; Davis, S; Heusinkveld, J | 1 |
| Cook, SP; McCleskey, EW; Sutherland, SP | 1 |
| Baumert, H; Carretier, M; Eugene, M; Gibelin, H; Goujon, JM; Hameury, F; Hauet, T | 1 |
| Bell, MJ; Carcillo, JA; Clark, RS; Goodman, JC; Gopinath, SP; Jackson, EK; Kochanek, PM; Marion, DW; Mi, Z; Robertson, CS | 1 |
| Bliss, TM; Sapolsky, RM | 1 |
| Bjerner, T; Henze, A; Ronquist, G; Thelin, S; Waldenström, A; Wikström, G; Zemgulis, V | 1 |
| Okada, Y; Sakurai, T; Takata, T; Yang, B; Yokono, K | 1 |
| Biondi, C; Dalpiaz, A; Forni, F; Pavan, B; Scatturin, A; Vandelli, MA | 2 |
| de Talancé, N; Devaux, Y; Grosjean, S; Mairose, P; Mertes, PM; Seguin, C; Siaghy, EM; Ungureanu-Longrois, D; Zannad, F | 1 |
| Kavianipour, M; Ronquist, G; Waldenström, A; Wikström, G | 2 |
| Schenkman, KA | 1 |
| Hagl, C; Haverich, A; Klima, U; Schulze, B; Warnecke, G | 1 |
| Aiba, M; Iwazaki, S; Matsumoto, K; Morishita, Y; Ohwada, S; Sunose, Y; Takeyoshi, I; Totsuka, O; Tsutsumi, H | 1 |
| Takeya, M | 1 |
| Bocking, AD; Fraher, L; Harding, R; Homan, JH; Schaefer, R; Watson, CS; White, SE | 1 |
| Blood, AB; Hunter, CJ; Power, GG | 2 |
| Alanko, L; Heiskanen, S; Kalinchuk, AV; Porkka-Heiskanen, T; Stenberg, D; Suomela, M; Urrila, AS; Wigren, HK | 1 |
| Fuller, BJ; So, PW | 1 |
| Bolli, R; Leesar, MA; Stoddard, MF; Tang, XL; Xuan, YT | 1 |
| ESTLER, CJ | 1 |
| GUENTHER, T; HOELSCHER, B | 1 |
| Bortolotti, F; Brina, B; Dalpiaz, A; Durini, E; Forni, F; Leo, E; Manfredini, S; Pavan, B; Scatturin, A; Vandelli, MA; Vitali, F | 1 |
| Driedzic, WR; Maccormack, TJ | 2 |
| Hagen, JL; Hepple, RT; Kindig, CA; Krause, DJ | 1 |
| Almeida, C; Barros, A; Duarte, IF; Gil, AM; Rodrigues, J; Spraul, M | 1 |
| Dankof, A; Neuhaus, P; Neumann, U; Olschewski, P; Puhl, G; Schöning, W; Settmacher, U; Sredznizki, D | 1 |
| Kalinchuk, AV; Porkka-Heiskanen, T; Rosenberg, PA; Stenberg, D | 1 |
| Duarte, AI; Oliveira, CR; Proença, T; Rego, AC; Santos, MS | 1 |
| Kalinchuk, AV; Lu, Y; Porkka-Heiskanen, T; Rosenberg, PA; Stenberg, D | 1 |
| Bünger, R; Duschek, C; Lasley, RD; Schulze, K | 1 |
| Inuzuka, K; Konno, H; Nishiyama, M; Sagara, D; Suzuki, M; Unno, N; Yamamoto, N | 1 |
| Choi, HB; Ellis-Davies, GC; Gordon, GR; MacVicar, BA; Rungta, RL | 1 |
| Dalpiaz, A; Leo, E; Pavan, B; Vighi, E | 1 |
| Arnaud, P; Bon, P; Déchelotte, P; Kalimouttou, S; Lahiani-Skiba, M; Skiba, M | 1 |
| Alvarez-Ayuso, L; Calero, P; Fernández-García, H; García Gómez-Heras, S; García-Poblete, E; Guardiola, JM; Jorge, E; Millán, I; Roda, JR; Torralba, A | 1 |
| Biber, B; Haney, M; Kavianipour, M; Moritz, T; Ronquist, G; Strandén, P; Waldenström, A; Wikström, G | 1 |
| Blackburn, MR; Daniels, IS; Lee, CC; Miki, T; O'Brien, WG; Tao, Z; Zhang, J; Zhao, Z | 1 |
| Dobson, GP; Rudd, DM | 1 |
| Ishibashi, T; Kaneshiro, T; Machii, H; Maruyama, Y; Saitoh, S; Takeishi, Y; Yamaguchi, O | 1 |
| Aberg, AM; Abrahamsson, P; Ahlström, K; Biber, B; Haney, M; Hauck, P; Johansson, G; Ronquist, G; Waldenström, A | 1 |
| Annecke, T; Becker, BF; Conzen, P; Fischer, J; Hartmann, H; Rehm, M; Sommerhoff, CP; Tschoep, J | 1 |
| Heedfeld, V; Liu, Q; Monbaliu, D; Pirenne, J; van Pelt, J; Vekemans, K; Wylin, T | 1 |
| Ahlsson, A; Bomfim, V; Jansson, E; Kaijser, L; Sobrosa, C | 1 |
| Ayers, C; Cobert, ML; Jessen, ME; Merritt, ME; Peltz, M; West, LM | 1 |
| Basheer, R; Kalinchuk, AV; McCarley, RW; Porkka-Heiskanen, T | 1 |
| Abbasciano, R; Biancari, F; Covajes, C; Dobson, GP; Faggian, G; Fanti, D; Gottin, L; Mazzucco, A; Menon, T; Onorati, F; San Biagio, L | 1 |
| Avanzini, MA; Bruno, S; Canevari, S; Corradetti, V; Dal Canton, A; De Cecco, L; Dugo, M; Esposito, P; Gregorini, M; Libetta, C; Maestri, M; Mantelli, M; Milanesi, S; Pattonieri, EF; Peloso, A; Rampino, T; Rocca, C | 1 |
| Azuma, H; Bochimoto, H; Furukawa, H; Gochi, M; Ishihara, Y; Kanazawa, H; Matsuno, N; Nishikawa, Y; Obara, H; Otani, M; Sakai, H; Shonaka, T; Yoshikawa, R | 1 |
| Ahmad, T; Byun, H; Kim, EM; Lee, J; Madhurakkat Perikamana, SK; Shin, H; Shin, HJ; Shin, YM | 1 |
| Dobson, GP; Granfeldt, A; Jensen, TH; Letson, HL; Mattson, TH | 1 |
| Asami, Y; Fukuuchi, T; Kaneko, K; Kano, H; Saito, C; Yamada, N; Yamaoka, N | 1 |
| Adjei, IM; Cheng, H; Murphy, DA; Yan, X; Yang, T | 1 |
| Bingham, J; Conner, J; Dobson, G; Eckert, M; Holtestaul, T; Jones, I; Kuckelman, J; Lammers, D; Letson, H | 1 |
| Delgoffe, GM; Watson, MJ | 1 |
| Dai, Z; Li, H; Qu, R; Tang, J; Wang, Q; Wu, M; Yang, Y; Yu, C; Zhen, X | 1 |
5 review(s) available for lactic acid and adenosine
| Article | Year |
|---|---|
Metabolic factors involved in regulation of muscle blood flow.
Topics: Adenosine; Animals; Capillary Permeability; Carbon Dioxide; Humans; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Muscle Contraction; Muscles; Osmolar Concentration; Oxygen; Phosphates; Potassium | 1985 |
Cyclic nucleotides in stroke and related cerebrovascular disorders.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Adenosine; Adenylyl Cyclases; Animals; Brain; Brain Ischemia; Brain Neoplasms; Capillaries; Cerebrovascular Disorders; Cyclic AMP; Cyclic GMP; gamma-Aminobutyric Acid; Guanylate Cyclase; Humans; Hypoxia, Brain; In Vitro Techniques; Lactates; Lactic Acid; Norepinephrine; Phospholipids; Protein Kinases; Synaptic Membranes; Tissue Distribution | 1985 |
[Metabolic aspects of myocardial ischemia].
Topics: Adenosine; Animals; Blood Glucose; Coronary Circulation; Energy Metabolism; HSP70 Heat-Shock Proteins; Humans; Lactic Acid; Myocardial Ischemia | 1998 |
Chemical mediators of pain due to tissue damage and ischemia.
Topics: Acetylcholine; Acid Sensing Ion Channels; Adenosine; Adenosine Triphosphate; Afferent Pathways; Animals; Bradykinin; Glutamic Acid; Heart; Humans; Lactic Acid; Membrane Proteins; Myocardial Ischemia; Nerve Tissue Proteins; Neurons, Afferent; Nociceptors; Pain; Potassium; Proton Pumps; Receptors, Purinergic P2; Signal Transduction; Sodium Channels | 2000 |
Fighting in a wasteland: deleterious metabolites and antitumor immunity.
Topics: Adenosine; Animals; Humans; Immunotherapy; Kynurenine; Lactic Acid; Neoplasms; Reactive Oxygen Species; Tumor Microenvironment | 2022 |
3 trial(s) available for lactic acid and adenosine
| Article | Year |
|---|---|
Comparison of coronary hemodynamics during infusions of dobutamine and adenosine in patients with angina pectoris.
Topics: Adenosine; Aged; Angina Pectoris; Blood Pressure; Chest Pain; Dobutamine; Electrocardiography; Female; Heart; Heart Rate; Hemodynamics; Humans; Infusions, Intravenous; Lactic Acid; Male; Middle Aged; Myocardial Ischemia; Myocardium; Oxygen Consumption | 1998 |
Adenosine in cold blood cardioplegia--a placebo-controlled study.
Topics: Adenine Nucleotides; Adenosine; Aged; Biopsy; Cold Temperature; Dose-Response Relationship, Drug; Double-Blind Method; Female; Heart Arrest, Induced; Heart Valve Diseases; Heart Valve Prosthesis Implantation; Humans; Intraoperative Complications; Lactic Acid; Male; Myocardial Reperfusion Injury; Myocardium; Oxygen Consumption; Prospective Studies; Treatment Outcome; Vasodilator Agents | 2012 |
Superior Myocardial Protection Using "Polarizing" Adenosine, Lidocaine, and Mg2+ Cardioplegia in Humans.
Topics: Adenosine; Aortic Valve; Cardioplegic Solutions; Coronary Artery Bypass; Heart Arrest, Induced; Heart Valve Prosthesis Implantation; Humans; Lactic Acid; Length of Stay; Lidocaine; Magnesium; Oxygen; Potassium; Prospective Studies; Troponin I | 2016 |
165 other study(ies) available for lactic acid and adenosine
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Activating effect of adenosine on rat erythrocyte glycolysis.
Topics: Adenosine; Animals; Enzyme Activation; Erythrocytes; Fructosediphosphates; Glycolysis; Kinetics; Lactates; Lactic Acid; Male; Phosphofructokinase-1; Rats; Rats, Inbred Strains | 1992 |
Dilation of coronary microvessels by adenosine induced hypotension in dogs.
Topics: Adenosine; Animals; Arterioles; Blood Gas Analysis; Coronary Circulation; Coronary Vessels; Dogs; Female; Hemodynamics; Hypotension; Lactates; Lactic Acid; Male; Microcirculation; Oxygen; Perfusion; Venules | 1992 |
Effect of hypercorticism on regulation of skeletal muscle glycogen metabolism by epinephrine.
Topics: Adenosine; Adrenocortical Hyperfunction; Animals; Epinephrine; Glucose-6-Phosphate; Glucosephosphates; Glycogen; Glycogen Synthase; Lactates; Lactic Acid; Male; Nucleotides; Osmolar Concentration; Phosphorylase a; Phosphorylases; Rats; Rats, Inbred Strains | 1992 |
The influence of lactic acid on adenosine release from skeletal muscle in anaesthetized dogs.
Topics: Adenosine; Animals; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Gases; Hemodynamics; Hydrogen-Ion Concentration; Infusions, Intra-Arterial; Lactates; Lactic Acid; Muscle Contraction; Muscles | 1991 |
Enhanced restoration of adenine nucleotides in rat liver following extended preservation in UW solution by provision of adenosine during reperfusion.
Topics: Adenine Nucleotides; Adenosine; Allopurinol; Animals; Fasting; Glutathione; Hypoxanthine; Hypoxanthines; Insulin; Lactates; Lactic Acid; Liver; Liver Glycogen; Liver Transplantation; Male; Organ Preservation; Organ Preservation Solutions; Perfusion; Raffinose; Rats; Rats, Inbred Strains; Solutions; Time Factors; Transplantation, Homologous | 1991 |
Importance of vasomotor tone to myocardial function and regional metabolism during constant flow ischaemia in swine.
Topics: Adenosine; Animals; Blood Pressure; Coronary Circulation; Coronary Disease; Female; Heart; Lactates; Lactic Acid; Male; Myocardial Contraction; Myocardium; Oxygen Consumption; Swine; Vasomotor System | 1990 |
Increased myocardial adenosine production and reduction of beta-adrenergic contractile response in aged hearts.
Topics: Adenosine; Aging; Animals; Calcium; Coronary Vessels; Guinea Pigs; Inosine; Lactates; Lactic Acid; Male; Myocardial Contraction; Myocardium; Osmolar Concentration; Oxygen Consumption; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Veins | 1990 |
Adenosine and active hyperemia in soleus and gracilis muscle of cats.
Topics: Adenosine; Adenosine Deaminase; Animals; Blood Volume; Cats; Female; Hemodynamics; Hindlimb; Lactates; Lactic Acid; Male; Microspheres; Muscles; Oxygen Consumption; Regional Blood Flow | 1990 |
Changes in cortical extracellular levels of energy-related metabolites and amino acids following concussive brain injury in rats.
Topics: Adenosine; Amino Acids; Animals; Body Temperature; Brain Concussion; Cerebral Cortex; Chromatography, High Pressure Liquid; Energy Metabolism; Extracellular Space; Hypoxanthine; Hypoxanthines; Inosine; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Rats | 1990 |
Metabolic factors from exercising muscle and the proliferation of endothelial cells.
Topics: Adenosine; Animals; Cell Division; Cells, Cultured; Dogs; Endothelium; Female; Hindlimb; Hydrogen-Ion Concentration; Lactates; Lactic Acid; Male; Muscle Contraction; Muscles; Neovascularization, Pathologic; Oxygen; Physical Exertion | 1986 |
Metabolic effects of acetate on the heart.
Topics: Acetates; Acetic Acid; Adenosine; Adenosine Triphosphate; Animals; Chromatography, High Pressure Liquid; Coronary Circulation; Dipyridamole; Glucose; Heart; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Myocardium; Phosphates; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Theophylline; Vasodilation | 1989 |
Inhibition of prolyl hydroxylase by poly(ADP-ribose) and phosphoribosyl-AMP. Possible role of ADP-ribosylation in intracellular prolyl hydroxylase regulation.
Topics: Adenosine; Adenosine Diphosphate Ribose; Adenosine Monophosphate; Animals; Cell Nucleus; Chick Embryo; Enzyme Activation; Fibroblasts; Hydroxylation; Lactates; Lactic Acid; Liver; Mixed Function Oxygenases; NAD; Nucleoside Diphosphate Sugars; Phosphodiesterase I; Phosphoric Diester Hydrolases; Poly Adenosine Diphosphate Ribose; Procollagen; Procollagen-Proline Dioxygenase; Rabbits; Rats | 1989 |
Glycolytic support of adenine nucleotides in rat liver flush-preserved with UW or Collins' II. Importance of donor nutritional status.
Topics: Adenine Nucleotides; Adenosine; Allopurinol; Animals; Glutathione; Glycolysis; Hypertonic Solutions; Insulin; Lactates; Lactic Acid; Liver; Liver Transplantation; Male; Nutritional Status; Organ Preservation; Organ Preservation Solutions; Organ Size; Raffinose; Rats; Rats, Inbred Strains; Solutions | 1989 |
Persistent right coronary flow reserve at low perfusion pressure.
Topics: Adenosine; Animals; Coronary Circulation; Coronary Vessels; Dogs; Female; Homeostasis; Lactates; Lactic Acid; Male; Myocardium; Oxygen Consumption; Pressure; Vasodilation | 1989 |
Release of adenosine and lactate from human hearts during atrial pacing in patients with ischemic heart disease.
Topics: Adenosine; Adult; Cardiac Pacing, Artificial; Coronary Disease; Female; Heart Atria; Hemodynamics; Humans; Lactates; Lactic Acid; Male; Middle Aged; Myocardium | 1989 |
Relative cerebral ischemia in SHR due to hypotensive hemorrhage: cerebral function, blood flow and extracellular levels of lactate and purine catabolites.
Topics: Adenosine; Animals; Brain; Brain Ischemia; Cerebral Hemorrhage; Cerebrovascular Circulation; Extracellular Space; Hypertension; Hypotension; Hypoxanthine; Hypoxanthines; Inosine; Kinetics; Lactates; Lactic Acid; Male; Rats; Rats, Inbred SHR; Xanthine; Xanthines | 1989 |
The mechanism by which adenosine decreases gluconeogenesis from lactate in isolated rat hepatocytes.
Topics: Adenine Nucleotides; Adenosine; Alanine; Animals; Cyclic AMP; Gluconeogenesis; In Vitro Techniques; Ketone Bodies; Lactates; Lactic Acid; Liver; Phosphates; Pyruvates; Pyruvic Acid; Rats | 1987 |
Alpha 1-adrenoceptor activity regulates release of adenosine from the ischemic myocardium in dogs.
Topics: Adenosine; Adrenergic alpha-Antagonists; Animals; Coronary Circulation; Dogs; Hyperemia; Ischemia; Lactates; Lactic Acid; Microspheres; Myocardium; Perfusion; Propranolol; Receptors, Adrenergic, alpha | 1987 |
Lactate release from cultured astrocytes and neurons: a comparison.
Topics: Adenosine; Animals; Astrocytes; Biological Transport, Active; Cells, Cultured; Intracellular Fluid; Inulin; Lactates; Lactic Acid; Neurons | 1988 |
Regulation of fructose 2,6-bisphosphate concentration in white adipose tissue.
Topics: Adenosine; Adipose Tissue; Adrenocorticotropic Hormone; Animals; Carbohydrate Metabolism; Fructosediphosphates; Glycerol; Hexosediphosphates; In Vitro Techniques; Insulin; Lactates; Lactic Acid; Lipolysis; Male; Norepinephrine; Phosphofructokinase-1; Rats; Rats, Inbred Strains | 1985 |
Effects of hyperthyroidism on the sensitivity of glycolysis and glycogen synthesis to insulin in the soleus muscle of the rat.
Topics: Adenosine; Animals; Fatty Acids, Nonesterified; Glucose; Glycogen; Glycolysis; Hexosephosphates; Hyperthyroidism; Insulin; Lactates; Lactic Acid; Male; Muscles; Phosphorylation; Rats; Rats, Inbred Strains; Triiodothyronine | 1988 |
Effect of metabolic products of muscular contraction on discharge of group III and IV afferents.
Topics: 2-Chloroadenosine; Adenosine; Afferent Pathways; Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Cats; Electric Stimulation; Indomethacin; Kinetics; Lactates; Lactic Acid; Muscle Contraction; Muscles; Nerve Fibers; Phosphates; Reference Values | 1988 |
Stimulation of protein synthesis, glucose uptake and lactate output by insulin and adenosine deaminase in the rat heart.
Topics: Adenosine; Adenosine Deaminase; Animals; Glucose; Heart Atria; Heart Ventricles; Insulin; Lactates; Lactic Acid; Male; Myocardium; Nucleoside Deaminases; Protein Biosynthesis; Rats; Rats, Inbred Strains | 1986 |
Observations on the energy and redox state and protein synthetic rate in animal and human placentas.
Topics: Adenosine; Adenosine Triphosphate; Animals; Energy Metabolism; Female; Guinea Pigs; Humans; Inosine; Lactates; Lactic Acid; Oxidation-Reduction; Placenta; Pregnancy; Sheep | 1987 |
Coronary vasodilator reserve persists despite tachycardia and myocardial ischemia.
Topics: Adenosine; Animals; Blood Pressure; Coronary Circulation; Coronary Disease; Coronary Vessels; Heart; Heart Rate; Lactates; Lactic Acid; Microspheres; Oxygen Consumption; Swine; Tachycardia; Vasodilation | 1987 |
Role of adenosine in mediating the coronary vasodilative response to acute hypoxia.
Topics: Acute Disease; Adenosine; Adenosine Deaminase; Animals; Coronary Circulation; Coronary Vessels; Hemodynamics; Hypoxia; Lactates; Lactic Acid; Myocardium; Oxygen; Swine; Vasodilation | 1987 |
Prevention of reperfusional damage from ischemic myocardium.
Topics: Adenosine; Adenosine Triphosphate; Animals; Cardiopulmonary Bypass; Coronary Circulation; Glucose; Heart; Heart Arrest, Induced; Lactates; Lactic Acid; Male; Myocardium; Necrosis; Perfusion; Phosphocreatine; Postoperative Complications; Rats; Rats, Inbred Strains; Temperature | 1986 |
Increased insulin sensitivity in soleus muscle from cold-exposed rats: reversal by an adenosine-receptor agonist.
Topics: 2-Chloroadenosine; Adenosine; Animals; Carbon Radioisotopes; Cold Temperature; Glucose; Glycogen; Glycolysis; Insulin; Lactates; Lactic Acid; Male; Muscles; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, Purinergic | 1984 |
Effects of analogues of adenosine and methyl xanthines on insulin sensitivity in soleus muscle of the rat.
Topics: 1-Methyl-3-isobutylxanthine; 2-Chloroadenosine; Adenosine; Animals; Glucose; Glycogen; Glycolysis; Insulin; Lactates; Lactic Acid; Muscles; Phenylisopropyladenosine; Rats; Theophylline | 1984 |
Abnormalities in myocardial perfusion during tachycardia in dogs with left ventricular hypertrophy: metabolic evidence for myocardial ischemia.
Topics: Adenosine; Animals; Blood Pressure; Cardiac Pacing, Artificial; Cardiomegaly; Coronary Circulation; Coronary Disease; Dogs; Heart Rate; Lactates; Lactic Acid; Myocardium | 1984 |
Tissue adenosine content in active soleus and gracilis muscles of cats.
Topics: 5'-Nucleotidase; Adenosine; AMP Deaminase; Animals; Cats; Female; Hypoxanthine; Hypoxanthines; Inosine; Kinetics; Lactates; Lactic Acid; Male; Muscle Contraction; Muscles; Nucleotidases; Nucleotide Deaminases | 1983 |
Effect of adenosine deaminase and an adenosine analogue on insulin sensitivity in soleus muscle of the rat.
Topics: Adenosine; Adenosine Deaminase; Animals; Glycogen; Glycolysis; In Vitro Techniques; Insulin; Lactates; Lactic Acid; Muscles; Nucleoside Deaminases; Phenylisopropyladenosine; Rats | 1983 |
The mode of action of suramin on the filarial worm Brugia pahangi.
Topics: Adenosine; Animals; Brugia; Female; Filariasis; Filarioidea; Gerbillinae; Glucose; Intestinal Mucosa; Lactates; Lactic Acid; Leucine; Male; Suramin | 1983 |
Energy levels at systole vs. diastole in normal hamster hearts vs. myopathic hamster hearts.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cricetinae; Energy Metabolism; Heart Failure; Lactates; Lactic Acid; Mesocricetus; Myocardial Contraction; Myocardium; Oxygen Consumption; Phosphates; Phosphocreatine; Systole | 1983 |
[Changes of the acid-base status, serum lactate concentration and purine metabolism in reconstructive arterial surgery].
Topics: Acid-Base Equilibrium; Adenosine; Aorta, Abdominal; Humans; Hypoxanthine; Hypoxanthines; Inosine; Lactates; Lactic Acid; Middle Aged; Purines; Pyruvates; Pyruvic Acid; Uric Acid; Xanthine; Xanthines | 1983 |
In vivo induced malignant hyperthermia in pigs. I. Physiological and biochemical changes and the influence of dantrolene sodium.
Topics: Adenosine; Adenosine Triphosphate; Adenylate Kinase; Animals; Creatine; Dantrolene; Inosine Monophosphate; Lactates; Lactic Acid; Malignant Hyperthermia; Muscle Contraction; Muscles; Phosphocreatine; Pulmonary Gas Exchange; Swine | 1984 |
Action of adenosine on energy metabolism and on glucose-6-phosphate dehydrogenase in rat brains.
Topics: Adenosine; Animals; Brain; Energy Metabolism; Glucose; Glucosephosphate Dehydrogenase; In Vitro Techniques; Lactates; Lactic Acid; Male; Oxygen Consumption; Rats; Rats, Inbred Strains | 1984 |
Brain adenosine concentration during hypoxia in rats.
Topics: Acute Disease; Adenine Nucleotides; Adenosine; Animals; Arteries; Blood; Brain Chemistry; Carbon Dioxide; Freezing; Hypoxia, Brain; Lactates; Lactic Acid; Oxygen; Partial Pressure; Phosphocreatine; Rats; Time Factors | 1981 |
Role of adenosine in the maintenance of coronary vasodilation distal to a severe coronary artery stenosis. Observations in conscious domestic swine.
Topics: Adenosine; Adenosine Deaminase; Animals; Coronary Circulation; Coronary Disease; Coronary Vessels; Extracellular Space; Lactates; Lactic Acid; Myocardium; Oxygen Consumption; Swine; Vasodilation | 1983 |
Metabolism of Babesia parasites in vitro. Glucose and energy-metabolism and survival of Babesia rodhaini in a basal medium with and without adenosine.
Topics: Adenosine; Adenosine Triphosphate; Animals; Babesia; Culture Media; Erythrocytes; Glucose; Lactates; Lactic Acid; Rats; Rats, Inbred Lew | 1982 |
Coronary arterial vasodilator effect of ibuprofen.
Topics: Adenosine; Animals; Coronary Vessels; Ibuprofen; In Vitro Techniques; Lactates; Lactic Acid; Myocardium; Oxygen; Rabbits; Vascular Resistance; Vasodilator Agents | 1982 |
Relationships between adenosine and coronary resistance in conscious exercising dogs.
Topics: Adenosine; Animals; Cardiac Output; Dogs; Female; Heart; Heart Rate; Lactates; Lactic Acid; Male; Myocardium; Oxygen Consumption; Physical Exertion; Pyruvates; Pyruvic Acid; Vascular Resistance | 1982 |
Myocardial lactate and adenosine metabolite production as indicators of exercise-induced myocardial ischemia in the dog.
Topics: Adenosine; Analysis of Variance; Animals; Coronary Circulation; Coronary Disease; Dogs; Hemodynamics; Lactates; Lactic Acid; Myocardium; Physical Exertion | 1982 |
Role of mitochondrial oxidative phosphorylation in regulation of coronary blood flow.
Topics: Adenosine; Amobarbital; Animals; Calcium; Coronary Circulation; Hypoxanthines; Hypoxia; Inosine; Lactates; Lactic Acid; Male; Mitochondria, Heart; Oxidative Phosphorylation; Oxygen Consumption; Phosphates; Physical Exertion; Rats; Theophylline | 1982 |
Effect of adenosine on gluconeogenesis in the perfused liver of chicken and guinea-pig.
Topics: Adenosine; Animals; Aspartic Acid; Chickens; Female; Gluconeogenesis; Guinea Pigs; Humans; Lactates; Lactic Acid; Liver; Malates; Perfusion; Pyruvates; Pyruvic Acid | 1981 |
Hypoxanthine production by ischemic heart demonstrated by high pressure liquid chromatography of blood purine nucleosides and oxypurines.
Topics: Adenosine; Angina Pectoris; Chromatography, High Pressure Liquid; Clinical Laboratory Techniques; Coronary Disease; Erythrocytes; Humans; Hypoxanthines; Inosine; Lactates; Lactic Acid; Plasma; Purine Nucleosides; Xanthines | 1981 |
Myocardial interstitial purine metabolites and lactate with increased work in swine.
Topics: Adenosine; Adenosine Monophosphate; Animals; Coronary Circulation; Dobutamine; Extracellular Space; Heart Rate; Lactates; Lactic Acid; Male; Microdialysis; Models, Biological; Myocardium; Oxygen Consumption; Purines; Receptors, Adrenergic, beta; Regional Blood Flow; Swine; Ventricular Pressure | 1995 |
Bidirectional effects of aminophylline on myocardial ischemia.
Topics: Adenosine; Aminophylline; Animals; Coronary Circulation; Dogs; Heart; Lactates; Lactic Acid; Myocardial Contraction; Myocardial Ischemia; Myocardium; Prazosin; Purinergic P1 Receptor Antagonists; Receptors, Adrenergic, alpha-1; Receptors, Purinergic P1; Reproducibility of Results; Theophylline | 1995 |
Does interstitial adenosine mediate acute hibernation of guinea pig myocardium?
Topics: 5'-Nucleotidase; Acute Disease; Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cytosol; Guinea Pigs; Heart; Inosine; Lactates; Lactic Acid; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Stunning; Myocardium; Phosphorylation; Theophylline | 1995 |
Continuous monitoring of energy metabolites using microdialysis during myocardial ischaemia in the pig.
Topics: Adenosine; Animals; Energy Metabolism; Female; Guanosine; Hemodynamics; Hypoxanthine; Hypoxanthines; Inosine; Lactates; Lactic Acid; Male; Microdialysis; Monitoring, Physiologic; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Pyruvates; Pyruvic Acid; Swine | 1995 |
Metabolic determinants of defibrillation. Role of adenosine.
Topics: Adenosine; Animals; Catecholamines; Dogs; Electric Countershock; Lactates; Lactic Acid; Theophylline; Ventricular Fibrillation | 1995 |
Inhibition of nitric oxide synthesis reduces infarct size by an adenosine-dependent mechanism.
Topics: Adenosine; Animals; Arginine; Lactates; Lactic Acid; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Perfusion; Rabbits; Theophylline; Time Factors | 1995 |
Vessel tone affects transmural distribution of coronary flow during hypoperfusion.
Topics: Adenosine; Animals; Blood Pressure; Coronary Circulation; Endothelins; Female; Hemodynamics; Lactates; Lactic Acid; Male; Myocardial Contraction; Myocardial Ischemia; Regional Blood Flow; Swine; Vascular Resistance; Vasoconstriction | 1995 |
Adenosine infusion does not improve maximal O2 uptake in isolated working dog muscle.
Topics: Acid-Base Equilibrium; Adenosine; Animals; Dogs; Electric Stimulation; Female; Infusions, Intravenous; Isometric Contraction; Lactates; Lactic Acid; Male; Muscle, Skeletal; Oxygen Consumption; Sciatic Nerve; Vascular Resistance | 1994 |
Pentostatin-augmented interstitial adenosine prevents postcardioplegia injury in damaged hearts.
Topics: Adenosine; Animals; Creatine Kinase; Dogs; Heart Arrest, Induced; Hypoxanthine; Hypoxanthines; Inosine; Lactates; Lactic Acid; Microdialysis; Models, Biological; Myocardial Reperfusion Injury; Pentostatin; Peroxidase; Premedication; Stroke Volume; Ventricular Function, Left; Xanthine; Xanthines | 1994 |
Ischaemic episodes of less than 5 minutes produce preconditioning but not stunning in the isolated rat heart.
Topics: Adenosine; Animals; Arrhythmias, Cardiac; Conditioning, Psychological; Coronary Circulation; Energy Metabolism; Glycolysis; Heart; Heart Rate; Hypoxanthines; Lactates; Lactic Acid; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Purine Nucleosides; Purine Nucleotides; Rats; Rats, Wistar; Ventricular Function, Left | 1994 |
Adenosine: a sensitive marker of myocardial ischaemia in man.
Topics: Adenosine; Aged; Angioplasty, Balloon, Coronary; Biomarkers; Coronary Circulation; Coronary Disease; Humans; Hypoxanthines; Lactates; Lactic Acid; Male; Middle Aged; Myocardial Ischemia; Nifedipine; Regional Blood Flow; Time Factors; Uric Acid | 1994 |
Possible role of cell redox state on collagen metabolism in carbon tetrachloride-induced cirrhosis as evidenced by adenosine administration to rats.
Topics: 3-Hydroxybutyric Acid; Adenosine; Animals; Carbon Tetrachloride; Collagen; Hydroxybutyrates; Lactates; Lactic Acid; Liver Cirrhosis, Experimental; Male; Mitochondria, Liver; NAD; Oxidation-Reduction; Pyruvates; Pyruvic Acid; Rats; Rats, Wistar | 1994 |
Improvement of ketoacidosis in the diabetic rat after the administration of the oral antilipolytic agent GR 79236.
Topics: Adenosine; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Ketoacidosis; Fatty Acids, Nonesterified; Lactates; Lactic Acid; Lipolysis; Male; Rats; Rats, Sprague-Dawley | 1994 |
Heterogeneous microvascular coronary vasodilation by adenosine and nitroglycerin in dogs.
Topics: Adenosine; Anesthesia; Animals; Blood Gas Analysis; Coronary Circulation; Coronary Vessels; Dogs; Female; Lactates; Lactic Acid; Male; Microcirculation; Microscopy, Fluorescence; Myocardium; Nitroglycerin; Oxygen Consumption; Regional Blood Flow; Vasodilation; Ventricular Function, Left | 1994 |
Interstitial glucose and lactate balance in human skeletal muscle and adipose tissue studied by microdialysis.
Topics: Adenosine; Adipose Tissue; Adolescent; Adult; Blood Flow Velocity; Ethanol; Exercise; Extracellular Space; Female; Glucose; Humans; Isometric Contraction; Lactates; Lactic Acid; Male; Microdialysis; Middle Aged; Muscles | 1993 |
Endocardial and epicardial interstitial purines and lactate during graded ischemia.
Topics: Adenosine; Animals; Coronary Circulation; Dogs; Endocardium; Extracellular Space; Female; Lactates; Lactic Acid; Male; Microdialysis; Myocardial Ischemia; Pericardium; Purines | 1994 |
Effect of ischemic preconditioning on interstitial purine metabolite and lactate accumulation during myocardial ischemia.
Topics: Adenosine; Animals; Dogs; Extracellular Space; Female; Hypoxanthine; Hypoxanthines; Inosine; Lactates; Lactic Acid; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Purines; Time Factors | 1994 |
Interstitial purine metabolites and lactate during regional myocardial hypoxia.
Topics: Adenosine; Animals; Cardiomyopathies; Coronary Circulation; Dialysis; Dogs; Extracellular Space; Female; Hypoxanthine; Hypoxanthines; Hypoxia; Inosine; Lactates; Lactic Acid; Male; Oxygen Consumption; Purines; Xanthine; Xanthines | 1993 |
Attenuation of postischaemic dysfunction by ischaemic preconditioning is not mediated by adenosine in the isolated rat heart.
Topics: Adenosine; Animals; Blood Pressure; Heart Rate; Lactates; Lactic Acid; Male; Myocardial Infarction; Myocardial Ischemia; Myocardium; Phenylisopropyladenosine; Purinergic Antagonists; Rats; Rats, Sprague-Dawley; Xanthines | 1993 |
Influence of stimulation parameters on the release of adenosine, lactate and CO2 from contracting dog gracilis muscle.
Topics: Adenosine; Animals; Blood Gas Analysis; Carbon Dioxide; Dogs; Electric Stimulation; Hemodynamics; Hydrogen-Ion Concentration; Hypoxia; In Vitro Techniques; Lactates; Lactic Acid; Muscle Contraction; Muscles; Oxygen Consumption; Perfusion; Vascular Resistance | 1993 |
Suppression of non-esterified fatty acids and triacylglycerol in experimental animals by the adenosine analogue GR79236.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Blood Glucose; Cells, Cultured; Dogs; Dose-Response Relationship, Drug; Fasting; Fatty Acids, Nonesterified; Female; In Vitro Techniques; Lactates; Lactic Acid; Lipolysis; Male; Rats; Rats, Inbred Strains; Triglycerides | 1993 |
Adenosine effect on lactate and pyruvate production in the hypoxic guinea pig heart.
Topics: Adenosine; Animals; Guinea Pigs; Heart; Hypoxia; In Vitro Techniques; Lactates; Lactic Acid; Myocardium; Pyruvates; Pyruvic Acid | 1993 |
Glucose deprivation results in a lactate preventable increase in adenosine and depression of synaptic transmission in rat hippocampal slices.
Topics: Adenosine; Animals; Cytochalasin B; Electrophysiology; Glucose; Hippocampus; In Vitro Techniques; Kinetics; Lactates; Lactic Acid; Male; Pyramidal Tracts; Rats; Rats, Sprague-Dawley; Synapses; Synaptic Transmission; Theophylline | 1993 |
Adenosine alters glucose use during ischemia and reperfusion in isolated rat hearts.
Topics: Adenosine; Adenosine Triphosphate; Animals; Coronary Disease; Female; Glucose; Glycogen; Glycolysis; Homeostasis; In Vitro Techniques; Lactates; Lactic Acid; Male; Myocardial Reperfusion; Myocardium; Oxidation-Reduction; Rats; Rats, Sprague-Dawley | 1993 |
Superoxide dismutase restores contractile and metabolic dysfunction through augmentation of adenosine release in coronary microembolization.
Topics: 5'-Nucleotidase; Adenosine; Animals; Coronary Circulation; Dogs; Embolism; Injections; Lactates; Lactic Acid; Microspheres; Myocardial Contraction; Myocardial Ischemia; Myocardium; Superoxide Dismutase; Theophylline; Time Factors; Vasodilation | 1993 |
Adenosine increases lactate release and delays onset of contracture during global low flow ischaemia.
Topics: Adenine; Adenosine; Animals; Glucose; Lactates; Lactic Acid; Male; Myocardial Contraction; Myocardial Ischemia; Rats; Rats, Wistar; Xanthines | 1993 |
Effect of adenosine on glucose metabolism of Rana ridibunda erythrocytes.
Topics: Adenosine; Adenosine Triphosphate; Animals; Blood Glucose; Erythrocytes; Glycolysis; Inosine; Iodoacetates; Iodoacetic Acid; Lactates; Lactic Acid; Ouabain; Rana ridibunda | 1993 |
A protective role of nitric oxide in isolated ischaemic/reperfused rat heart.
Topics: Adenosine; Animals; Arginine; Coronary Circulation; Heart; Lactates; Lactic Acid; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Perfusion; Rats; Rats, Wistar | 1995 |
Role of adenosine in regulation of coronary flow in dogs with inhibited synthesis of endothelium-derived nitric oxide.
Topics: Adenosine; Animals; Atrial Function; Cardiac Pacing, Artificial; Coronary Circulation; Dogs; Endothelium, Vascular; Gases; Heart Rate; Hemodynamics; Injections, Intra-Arterial; Lactic Acid; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxygen Consumption; Theophylline | 1996 |
Role of adenosine in pathogenesis of syndrome X: assessment with coronary hemodynamic measurements and thallium-201 myocardial single-photon emission computed tomography.
Topics: Adenosine; Adult; Aged; Dobutamine; Exercise Test; Female; Hemodynamics; Humans; Lactic Acid; Male; Microvascular Angina; Middle Aged; Oxygen Consumption; Thallium Radioisotopes; Tomography, Emission-Computed, Single-Photon | 1996 |
Endogenous adenosine increases O2 utilisation efficiency in isoprenaline-stimulated canine myocardium.
Topics: Adenine; Adenosine; Adenosine Deaminase; Adrenergic beta-Agonists; Animals; Dogs; Hypoxia; Isoproterenol; Lactic Acid; Myocardial Contraction; Myocardial Ischemia; Myocardium; Oxygen; Oxygen Consumption; Perfusion; Stimulation, Chemical | 1996 |
Biochemical and morphological changes in isolated rabbit hearts after prolonged hypothermic ischaemia: comparison of two cardioplegic solutions.
Topics: Adenosine; Allopurinol; Animals; Bicarbonates; Calcium Chloride; Cardioplegic Solutions; Creatine Kinase; Cryopreservation; Energy Metabolism; Glutathione; In Vitro Techniques; Insulin; Lactic Acid; Magnesium; Myocardial Ischemia; Myocardium; Organ Preservation Solutions; Phosphates; Potassium Chloride; Rabbits; Raffinose; Sodium Chloride; Time Factors | 1995 |
The measurement of extracellular inorganic phosphate gives a more reliable indication for severe impairment of cerebral cell function and cell death than the measurement of extracellular lactate.
Topics: Adenosine; Animals; Brain; Cell Death; Extracellular Space; Lactic Acid; Male; Microdialysis; Neurons; Osmolar Concentration; Phosphates; Rats; Rats, Wistar | 1996 |
Metabolic effects of ischemic preconditioning and adenosine receptor blockade in dogs.
Topics: Adenosine; Animals; Creatine; Dogs; Female; Lactic Acid; Male; Myocardial Ischemia; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline; Vasodilator Agents | 1996 |
Metabolic analysis of the rabbit cornea by proton nuclear magnetic resonance spectroscopy.
Topics: Acetates; Adenosine; Amino Acids; Animals; Choline; Cornea; Creatinine; Glucose; Lactic Acid; Magnetic Resonance Spectroscopy; Rabbits; Taurine | 1996 |
Intracellular lactate controls adenosine output from dog gracilis muscle during moderate systemic hypoxia.
Topics: Adenosine; Animals; Dogs; Gases; Hemodynamics; Hindlimb; Hydrogen-Ion Concentration; Hypoxia; Intracellular Fluid; Intracellular Membranes; Lactic Acid; Male; Muscle, Skeletal; Osmolar Concentration; Rats; Rats, Sprague-Dawley | 1997 |
Adenosine receptor blockade enhance glycolysis in hypoperfused guinea-pig myocardium.
Topics: Adenosine; Animals; Enzyme Activation; Glucose; Glycogen; Glycolysis; Guinea Pigs; In Vitro Techniques; Lactic Acid; Myocardial Ischemia; Myocardium; Oxidation-Reduction; Perfusion; Phosphofructokinase-1; Purinergic P1 Receptor Antagonists; Theophylline; Ventricular Function, Left | 1997 |
Correlation of adenosine thallium 201 perfusion patterns with markers for inducible ischemia.
Topics: Adenosine; Coronary Angiography; Coronary Circulation; Coronary Disease; Echocardiography; Electrocardiography; Heart; Hemodynamics; Humans; Lactic Acid; Myocardial Ischemia; Pulmonary Wedge Pressure; Radionuclide Imaging; Sensitivity and Specificity; Thallium Radioisotopes; Vasodilator Agents | 1997 |
Myocardial protection with special reference to ischemic preconditioning. An experimental study in the pig using a microdialysis technique.
Topics: Adenosine; Adenosine Triphosphate; Animals; Glyburide; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Lactic Acid; Microdialysis; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Potassium Channel Blockers; Potassium Channels; Swine | 1997 |
On the cardioprotective effect of adenosine.
Topics: Adenosine; Adenosine Triphosphate; Animals; Glycogen; Guinea Pigs; Heart; Hypoxia; In Vitro Techniques; Lactic Acid; Myocardium; Phosphocreatine; Reference Values | 1996 |
Intermittent ischemia: energy metabolism, cellular volume regulation, adenosine and insights into preconditioning.
Topics: Adenosine; Animals; Cell Size; Creatine; Energy Metabolism; Glyburide; Glycogen; Glycolysis; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Myocardial Contraction; Myocardial Ischemia; Myocardium; Perfusion; Phosphorus; Phosphorylation; Potassium Channels; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Theophylline | 1997 |
Plasma adenosine responses during repeated episodes of umbilical cord occlusion.
Topics: Adenosine; Animals; Blood Glucose; Blood Pressure; Constriction; Female; Fetal Blood; Heart Rate, Fetal; Hydrogen-Ion Concentration; Kinetics; Lactic Acid; Oxyhemoglobins; Pregnancy; Sheep; Umbilical Cord | 1997 |
Liver transplantation from non-heart beating donors in rats: influence of viscosity and temperature of initial flushing solutions on graft function.
Topics: Adenosine; Alanine Transaminase; Allopurinol; Animals; Chlorpromazine; Disaccharides; Glutathione; Graft Survival; Hydroxyethyl Starch Derivatives; Insulin; Isotonic Solutions; Lactic Acid; Liver; Liver Transplantation; Male; Organ Preservation; Organ Preservation Solutions; Raffinose; Rats; Rats, Wistar; Ringer's Solution; Solutions; Sucrose; Survival Rate; Temperature; Vascular Resistance; Viscosity | 1997 |
Cerebrospinal fluid adenosine concentration and uncoupling of cerebral blood flow and oxidative metabolism after severe head injury in humans.
Topics: Adenosine; Adolescent; Adult; Arteries; Cerebrovascular Circulation; Chromatography, High Pressure Liquid; Coma; Craniocerebral Trauma; Cyclic AMP; Female; Humans; Jugular Veins; Lactic Acid; Male; Middle Aged; Osmolar Concentration; Oxygen | 1997 |
Nitric oxide induced contractile dysfunction is related to a reduction in myocardial energy generation.
Topics: Adenosine; Adenosine Triphosphate; Animals; Coronary Circulation; Cyclic GMP; Dose-Response Relationship, Drug; Energy Metabolism; Guinea Pigs; Hydrolysis; Lactic Acid; Myocardial Contraction; Myocardium; Nitric Oxide; Norepinephrine; Oxygen Consumption; Perfusion; Phosphocreatine; Ventricular Pressure | 1997 |
Effects of ischemic preconditioning on contractile and metabolic function during hypoperfusion in dogs.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Diphosphate; Animals; Blood Flow Velocity; Coronary Circulation; Coronary Vessels; Dogs; Enzyme Inhibitors; Hydrogen-Ion Concentration; Ischemic Preconditioning, Myocardial; Lactic Acid; Myocardial Contraction; Myocardium; Purinergic P1 Receptor Antagonists; Theophylline | 1998 |
[Liver metabolism during cold ischemic incubation in UW solution in the rat model].
Topics: Adenosine; Allopurinol; Animals; Cell Hypoxia; Cell Survival; Cryopreservation; Energy Metabolism; Glutathione; Glycolysis; Insulin; L-Lactate Dehydrogenase; Lactic Acid; Liver Glycogen; Liver Transplantation; Male; Organ Preservation; Organ Preservation Solutions; Raffinose; Rats; Rats, Sprague-Dawley; Tissue Survival | 1997 |
Low concentrations of adenosine receptor blocker decrease protection by hypoxic preconditioning in ischemic rat hearts.
Topics: Adenosine; Adenosine Triphosphate; Animals; Creatine Kinase; Hypoxia; In Vitro Techniques; Ischemic Preconditioning, Myocardial; L-Lactate Dehydrogenase; Lactic Acid; Male; Myocardial Reperfusion Injury; Perfusion; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Theophylline; Ventricular Function, Left | 1998 |
Microsphere-induced bronchial artery vasodilation: role of adenosine, prostacyclin, and nitric oxide.
Topics: Adenine Nucleotides; Adenosine; Animals; Bronchial Arteries; Dipyridamole; Enzyme Inhibitors; Epoprostenol; Lactic Acid; Microspheres; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Sheep; Vasodilation; Xanthines | 1998 |
Adenosine, inosine, and guanosine protect glial cells during glucose deprivation and mitochondrial inhibition: correlation between protection and ATP preservation.
Topics: Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Amobarbital; Anaerobiosis; Animals; Astrocytes; Cell Hypoxia; Cell Survival; Coformycin; Dose-Response Relationship, Drug; Electron Transport; Enzyme Inhibitors; GABA Modulators; Glioma; Glucose; Glycolysis; Guanine Nucleotides; Guanosine; Hybrid Cells; Inosine; Inosine Monophosphate; Ischemia; Lactic Acid; Mitochondria; Neuroprotective Agents; Oligodendroglia; Pentosyltransferases; Purine Nucleosides; Rats | 1998 |
Brain temperature and metabolic responses during umbilical cord occlusion in fetal sheep.
Topics: Acidosis, Respiratory; Adenosine; Animals; Aorta; Blood Gas Analysis; Blood Glucose; Body Temperature; Body Temperature Regulation; Brain; Female; Fetus; Heart Rate; Jugular Veins; Lactic Acid; Ligation; Placenta; Pregnancy; Sheep; Umbilical Cord | 1998 |
Effects of intracellular N+, M2+ and metabolites on C2+-activated K+ channels in pulmonary and ear arterial smooth muscle cells of the rabbit.
Topics: Adenosine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arteries; Calcium; Ear, External; Electrophysiology; In Vitro Techniques; Lactic Acid; Magnesium; Muscle, Smooth, Vascular; Potassium Channels; Pulmonary Artery; Rabbits; Regional Blood Flow; Sodium | 1998 |
Efficiency of trimetazidine in renal dysfunction secondary to cold ischemia-reperfusion injury: a proposed addition to University of Wisconsin solution.
Topics: Adenosine; Allopurinol; Animals; Citric Acid; Cold Temperature; Glomerular Filtration Rate; Glutathione; Humans; Insulin; Kidney; Kidney Transplantation; Kidney Tubules; Lactic Acid; Lipid Peroxidation; Organ Preservation; Organ Preservation Solutions; Perfusion; Raffinose; Reperfusion Injury; Swine; Trimetazidine | 1998 |
Influence of an early adrenergic blockade on thrombotic infarct size and myocardial metabolism.
Topics: Adenosine; Adrenergic beta-Antagonists; Animals; Blood Glucose; Dogs; Fatty Acids, Nonesterified; Female; Lactic Acid; Male; Metoprolol; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Oxygen; Oxygen Consumption; Regional Blood Flow | 1998 |
Increase in myocardial interstitial adenosine and net lactate production in brain-dead pigs: an in vivo microdialysis study.
Topics: Adenosine; Animals; Blood Gas Analysis; Brain Death; Hemodynamics; Lactic Acid; Microdialysis; Myocardium; Swine; Time Factors | 1998 |
Subzero nonfreezing storage of isolated rat hepatocytes in University of Wisconsin solution.
Topics: Adenosine; Adenosine Triphosphate; Allopurinol; Animals; Cell Separation; Cryopreservation; Glutathione; Hypoxia; Insulin; Lactic Acid; Liver; Male; Microscopy, Electron, Scanning; Organ Preservation Solutions; Raffinose; Rats; Rats, Wistar; Tetrazolium Salts; Thiazoles; Trypan Blue | 1999 |
Shear stress-induced nitric oxide antagonizes adenosine effects on intestinal metabolism.
Topics: Adenosine; Animals; Blood Flow Velocity; Cats; Drug Synergism; Enzyme Inhibitors; Female; Hemorheology; Intestine, Small; Lactic Acid; Male; Mesenteric Artery, Superior; Molsidomine; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Oxygen; Oxygen Consumption; Vasodilation | 1999 |
Role of adenosine in local metabolic coronary vasodilation.
Topics: Adenosine; Animals; Coronary Circulation; Coronary Vessels; Dogs; Electrocardiography; Heart Rate; Heart Ventricles; Hyperemia; Lactic Acid; Male; Oxygen; Oxygen Consumption; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Theophylline; Vasodilation; Ventricular Function | 1999 |
Optimal myocardial preconditioning in humans.
Topics: Adenosine; Adenosine Triphosphate; Cells, Cultured; Coronary Artery Bypass; Energy Metabolism; Heart Ventricles; Humans; Ischemic Preconditioning, Myocardial; Lactic Acid; Myocardium; Purinergic P1 Receptor Antagonists; Theophylline | 1999 |
Adenosine: a sensitive indicator of cerebral ischemia during carotid endarterectomy.
Topics: Adenosine; Adenosine Triphosphate; Aged; Brain; Brain Ischemia; Cerebrovascular Circulation; Endarterectomy, Carotid; Evoked Potentials, Somatosensory; Female; Humans; Lactic Acid; Male; Middle Aged | 1999 |
Effect of Celsior and University of Wisconsin solutions on myocardial metabolism and function after warm ischemia.
Topics: Acid-Base Equilibrium; Adenosine; Allopurinol; Animals; Creatine Kinase; Dogs; Energy Metabolism; Glutathione; Insulin; Lactic Acid; Myocardial Ischemia; Organ Preservation; Organ Preservation Solutions; Potassium Compounds; Raffinose; Temperature; Troponin T; Ventricular Function, Left | 1999 |
Estimation of skeletal muscle interstitial adenosine during forearm dynamic exercise in humans.
Topics: Adenosine; Adult; Exercise; Female; Forearm; Humans; Lactic Acid; Male; Microdialysis; Muscle Contraction; Muscle, Skeletal; Reflex | 2000 |
The effect of lactic acid on intracellular pH and adenosine output from superfused rat soleus muscle fibres.
Topics: Adenosine; Animals; Buffers; Carbon Dioxide; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Fluoresceins; Fluorescent Dyes; Hydrogen-Ion Concentration; In Vitro Techniques; Lactic Acid; Male; Muscle Fibers, Fast-Twitch; Muscle, Skeletal; Oxygen; Partial Pressure; Rats; Rats, Sprague-Dawley | 2000 |
Noninvasive monitoring of citrate, acetate, lactate, and renal medullary osmolyte excretion in urine as biomarkers of exposure to ischemic reperfusion injury.
Topics: Acetic Acid; Acetylglucosaminidase; Acute Kidney Injury; Adenosine; Allopurinol; Animals; Biomarkers; Citric Acid; Cold Temperature; Creatinine; Dimethylamines; Glutathione; Glutathione Transferase; Hypertonic Solutions; Insulin; Isoenzymes; Kidney; Kidney Medulla; Kidney Transplantation; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Methylamines; Organ Preservation; Organ Preservation Solutions; Raffinose; Reperfusion Injury; Swine; Transplantation, Autologous | 2000 |
Interstitial brain adenosine and xanthine increase during jugular venous oxygen desaturations in humans after traumatic brain injury.
Topics: Adenosine; Adolescent; Adult; Blood Gas Analysis; Blood Glucose; Brain Chemistry; Brain Injuries; Cerebrovascular Circulation; Chromatography, High Pressure Liquid; Critical Illness; Cyclic AMP; Extracellular Space; Glycolysis; Humans; Hypoxia, Brain; Jugular Veins; Lactic Acid; Male; Microdialysis; Middle Aged; Oxygen Consumption; Prospective Studies; Xanthine | 2001 |
Interactions among glucose, lactate and adenosine regulate energy substrate utilization in hippocampal cultures.
Topics: Adenosine; Animals; Cell Hypoxia; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Energy Metabolism; Glucose; Hippocampus; Lactic Acid; Neuroglia; Neurons; Rats | 2001 |
Energy-related metabolites during and after induced myocardial infarction with special emphasis on the reperfusion injury after extracorporeal circulation.
Topics: Adenosine; Animals; Chromatography, High Pressure Liquid; Dialysis Solutions; Disease Models, Animal; Energy Metabolism; Extracorporeal Circulation; Guanine; Heart Arrest, Induced; Hypoxanthine; Inosine; Lactic Acid; Microdialysis; Myocardial Infarction; Myocardium; Pyruvic Acid; Reperfusion Injury; Swine; Taurine | 2001 |
Effect of lactate on the synaptic potential, energy metabolism, calcium homeostasis and extracellular glutamate concentration in the dentate gyrus of the hippocampus from guinea-pig.
Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Adenosine; Adenosine Triphosphate; Animals; Calcium; Calcium Channel Blockers; Calcium Signaling; Dentate Gyrus; Energy Metabolism; Excitatory Amino Acid Antagonists; Extracellular Space; Glutamic Acid; Glycolysis; Guinea Pigs; Homeostasis; Intracellular Fluid; Lactic Acid; Neurons; Nimodipine; Organ Culture Techniques; Phosphocreatine; Receptors, N-Methyl-D-Aspartate; Theophylline | 2001 |
Poly(lactic acid) microspheres for the sustained release of a selective A1 receptor agonist.
Topics: Adenosine; Cyclic AMP; Delayed-Action Preparations; Drug Stability; Humans; Lactic Acid; Microspheres; Polyesters; Polymers; Purinergic P1 Receptor Agonists; Xanthines | 2001 |
Evidence of functional myocardial ischemia associated with myocardial dysfunction in brain-dead pigs.
Topics: Adenosine; Animals; Blood Flow Velocity; Blood Gas Analysis; Blood Pressure; Brain Death; Cardiac Output; Cardiomyopathies; Coronary Circulation; Heart Rate; Labetalol; Lactic Acid; Microdialysis; Myocardial Ischemia; Myocardium; Oxygen; Oxygen Consumption; Swine; Sympatholytics; Ventricular Function, Left | 2001 |
Pre-conditioning activates adenosine utilization in a cost-effective way during myocardial ischaemia.
Topics: Adenosine; Animals; Deoxyadenosines; Female; Glycolysis; Inosine; Ischemic Preconditioning, Myocardial; Lactic Acid; Male; Microdialysis; Myocardial Ischemia; Myocardium; Pentose Phosphate Pathway; Swine | 2001 |
Cardiac performance as a function of intracellular oxygen tension in buffer-perfused hearts.
Topics: Adenosine; Animals; Buffers; Female; Guinea Pigs; In Vitro Techniques; Lactic Acid; Male; Myocardium; Myoglobin; Oxygen; Oxygen Consumption; Perfusion; Spectrum Analysis; Ventricular Function, Left; Ventricular Pressure | 2001 |
Improved right heart function after myocardial preservation with 2,3-butanedione 2-monoxime in a porcine model of allogenic heart transplantation.
Topics: Adenosine; Allopurinol; Animals; Calcium; Creatine Kinase; Creatine Kinase, MB Form; Diacetyl; Glucose; Glutathione; Heart Transplantation; Insulin; Isoenzymes; Isotonic Solutions; Lactic Acid; Mannitol; Myocardium; Organ Preservation; Organ Preservation Solutions; Potassium Chloride; Procaine; Raffinose; Swine; Ventricular Dysfunction, Right; Ventricular Function, Right; Ventricular Pressure | 2002 |
Advantages of Celsior solution in graft preservation from non-heart-beating donors in a canine liver transplantation model.
Topics: Adenosine; Alanine Transaminase; Allopurinol; Animals; Aspartate Aminotransferases; Disaccharides; Dogs; Electrolytes; Endothelin-1; Female; Glutamates; Glutathione; Glutathione Transferase; Graft Survival; Heart Arrest; Histidine; Insulin; L-Lactate Dehydrogenase; Lactic Acid; Liver; Liver Circulation; Liver Transplantation; Male; Mannitol; Neutrophils; Organ Preservation Solutions; Raffinose | 2002 |
Intrinsic factors involved in the depression of neuronal activity induced by temperature increase in rat hippocampal neurons.
Topics: Adenosine; Animals; Glucose; Glyburide; Hippocampus; Lactic Acid; Male; Neurons; NG-Nitroarginine Methyl Ester; Pyruvic Acid; Rats; Rats, Wistar; Temperature; Vitamin B 12 | 2001 |
Effect of intermittent umbilical cord occlusion on fetal respiratory activity and brain adenosine in late-gestation sheep.
Topics: Adenosine; Animals; Blood Gas Analysis; Brain; Constriction, Pathologic; Female; Fetal Hypoxia; Gestational Age; Glucose; Hydrogen-Ion Concentration; Lactic Acid; Pregnancy; Pregnancy, Animal; Respiratory Mechanics; Sheep; Umbilical Cord | 2002 |
Poly(lactic acid) microspheres for the sustained release of antiischemic agents.
Topics: Adenosine; Animals; Cardiovascular Agents; Cell Membrane; Cells, Cultured; CHO Cells; Cricetinae; Delayed-Action Preparations; Drug Compounding; Humans; In Vitro Techniques; Lactic Acid; Microscopy, Electron, Scanning; Microspheres; Polyesters; Polymers; Receptors, Purinergic P1 | 2002 |
The role of adenosine in regulation of cerebral blood flow during hypoxia in the near-term fetal sheep.
Topics: Adenosine; Animals; Blood Glucose; Blood Pressure; Carbon Dioxide; Cerebrovascular Circulation; Female; Gestational Age; Heart Rate; Hemoglobins; Hydrogen-Ion Concentration; Hypoxia, Brain; Injections, Intravenous; Lactic Acid; Laser-Doppler Flowmetry; Oxygen; Pregnancy; Purinergic P1 Receptor Antagonists; Theophylline; Vascular Resistance; Vasodilator Agents | 2002 |
Local energy depletion in the basal forebrain increases sleep.
Topics: 2,4-Dinitrophenol; Adenosine; Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Circadian Rhythm; Dose-Response Relationship, Drug; Electroencephalography; Energy Metabolism; Enzyme Inhibitors; Lactic Acid; Male; Microdialysis; Potassium Cyanide; Prosencephalon; Pyruvic Acid; Rats; Sleep; Sleep Deprivation; Sleep Stages; Uncoupling Agents | 2003 |
Enhanced energy metabolism during cold hypoxic organ preservation: studies on rat liver after pyruvate supplementation.
Topics: Adenosine; Adenosine Triphosphate; Alanine; Allopurinol; Animals; Cryopreservation; Dose-Response Relationship, Drug; Drug Combinations; Energy Metabolism; Glutathione; Insulin; Lactic Acid; Liver; Male; Organ Preservation Solutions; Osmolar Concentration; Pyruvic Acid; Raffinose; Rats; Rats, Sprague-Dawley; Succinic Acid | 2003 |
Nonelectrocardiographic evidence that both ischemic preconditioning and adenosine preconditioning exist in humans.
Topics: Adenosine; Angioplasty, Balloon, Coronary; Echocardiography; Electrocardiography; Female; Heart; Humans; Hydrogen-Ion Concentration; Ischemic Preconditioning, Myocardial; Lactic Acid; Male; Middle Aged; Vasodilator Agents; Ventricular Dysfunction, Left | 2003 |
Validity of the microdialysis technique for experimental in vivo studies of myocardial energy metabolism.
Topics: Adenosine; Animals; Biopsy; Energy Metabolism; Hypoxanthine; Inosine; Lactic Acid; Microdialysis; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Reproducibility of Results; Swine | 2003 |
[Changes in the adenosine polyphosphate, creatine phosphate, glycogen and lactic acid contents, as well as in the co-enzyme A activity, of the brain in non-fatal potassium cyanide poisoning].
Topics: Adenine Nucleotides; Adenosine; Brain; Coenzymes; Cyanides; Glycogen; Glycogenolysis; Humans; Lactates; Lactic Acid; Neurochemistry; Phosphates; Phosphocreatine; Polyphosphates; Potassium; Potassium Cyanide | 1961 |
[The behavior of phosphocreatinine, adenosine nucleotides, orthophosphate, glycogen and lactic acid in the myocardium in different forms of heart arrest].
Topics: Adenosine; Coenzymes; Glycogen; Heart Arrest; Lactates; Lactic Acid; Myocardium; Nucleotides; Phosphates; Phosphocreatine | 1961 |
Adenosine mediates decreased cerebral metabolic rate and increased cerebral blood flow during acute moderate hypoxia in the near-term fetal sheep.
Topics: Adenosine; Animals; Blood Flow Velocity; Blood Gas Analysis; Blood Glucose; Brain; Cerebrovascular Circulation; Energy Metabolism; Fetal Hypoxia; Gestational Age; Hemoglobins; Infusions, Intravenous; Lactic Acid; Oxyhemoglobins; Purinergic P1 Receptor Antagonists; Sheep; Theophylline; Xanthines | 2003 |
Development and characterization of biodegradable nanospheres as delivery systems of anti-ischemic adenosine derivatives.
Topics: Absorbable Implants; Adenosine; Animals; CHO Cells; Cricetinae; Cricetulus; Delayed-Action Preparations; Diffusion; Drug Carriers; Humans; Lactic Acid; Metabolic Clearance Rate; Nanotubes; Particle Size; Polyesters; Polymers; Receptor, Adenosine A1; Vasodilator Agents | 2005 |
Cardiorespiratory and tissue adenosine responses to hypoxia and reoxygenation in the short-horned sculpin Myoxocephalus scorpius.
Topics: Adenosine; Animals; Brain; Calcium; Chromatography, High Pressure Liquid; Fishes; Hypoxia; Lactic Acid; Myocardium; Oxygen; Potassium; Respiratory Function Tests; Sodium; Time Factors | 2004 |
Nitric oxide synthase inhibition reduces the O2 cost of force development in rat hindlimb muscles pump perfused at matched convective O2 delivery.
Topics: Adenosine; Aerobiosis; Animals; Hindlimb; In Vitro Techniques; Lactic Acid; Male; Muscle Contraction; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxygen; Perfusion; Rats; Rats, Sprague-Dawley; Vasodilator Agents | 2005 |
Composition of beer by 1H NMR spectroscopy: effects of brewing site and date of production.
Topics: Adenosine; Beer; Dextrins; Environment; Lactic Acid; Magnetic Resonance Spectroscopy; Pyruvic Acid; Reproducibility of Results; Time Factors; Tyrosine; Uridine | 2006 |
24-h storage of pig livers in UW, HTK, hydroxyethyl starch, and saline solution: is microdialysis an appropriate method for the continuous graft monitoring during preservation?
Topics: Adenosine; Allopurinol; Animals; Aspartate Aminotransferases; Cold Temperature; Glucose; Glutathione; Glycerol; Hydroxyethyl Starch Derivatives; In Vitro Techniques; Insulin; L-Lactate Dehydrogenase; Lactic Acid; Liver; Male; Mannitol; Microdialysis; Monitoring, Physiologic; Organ Preservation; Organ Preservation Solutions; Potassium Chloride; Procaine; Pyruvic Acid; Raffinose; Sodium Chloride; Sus scrofa | 2006 |
Inducible and neuronal nitric oxide synthases (NOS) have complementary roles in recovery sleep induction.
Topics: Adenosine; Animals; Arginine; Electroencephalography; Electromyography; Imines; Lactic Acid; Lipopolysaccharides; Male; Microinjections; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Pyruvic Acid; Rats; Rats, Wistar; Sleep Deprivation; Sleep Stages; Wakefulness | 2006 |
Insulin restores metabolic function in cultured cortical neurons subjected to oxidative stress.
Topics: Adenine Nucleotides; Adenosine; Androstadienes; Animals; Cells, Cultured; Cerebral Cortex; Chromones; Flavonoids; Glucose; Insulin; Lactic Acid; Morpholines; Neurons; Oxidative Stress; Phosphocreatine; Pyruvic Acid; Rats; Rats, Wistar; Thioinosine; Wortmannin | 2006 |
The impact of hypoxia on in vivo glucose uptake in a hypoglycemic fish, Myoxocephalus scorpius.
Topics: Adenosine; Animals; Atropine; Blood Glucose; Brain Chemistry; Carbohydrate Metabolism; Cardiac Output; Deoxyglucose; Extracellular Fluid; Fishes; Glucose; Glucose-6-Phosphate; Heart Rate; Hypoxia; Lactic Acid; Muscarinic Antagonists; Phosphorylation; Purinergic P1 Receptor Antagonists; Theophylline; Tissue Distribution | 2007 |
Nitric oxide production in the basal forebrain is required for recovery sleep.
Topics: Adenosine; Animals; Diagonal Band of Broca; Energy Metabolism; Enzyme Inhibitors; Free Radical Scavengers; Lactic Acid; Male; Microdialysis; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Prosencephalon; Pyruvic Acid; Rats; Rats, Wistar; Recovery of Function; Signal Transduction; Sleep; Sleep Deprivation; Up-Regulation | 2006 |
Adenosine enhances cytosolic phosphorylation potential and ventricular contractility in stunned guinea pig heart: receptor-mediated and metabolic protection.
Topics: Adenosine; Adenosine Triphosphate; Animals; Coronary Circulation; Cytosol; Energy Metabolism; Female; Glucose-6-Phosphate; Guinea Pigs; Heart Rate; In Vitro Techniques; Inosine Monophosphate; Lactic Acid; Myocardial Contraction; Myocardial Reperfusion; Myocardium; Pentose Phosphate Pathway; Phosphates; Phosphorylation; Potassium Channels; Ventricular Function, Left | 2007 |
Effect of hyperbarically oxygenated-perfluorochemical with University of Wisconsin solution on preservation of rat small intestine using an original pressure-resistant portable apparatus.
Topics: Adenosine; Adenosine Triphosphate; Allopurinol; Animals; Atmospheric Pressure; Carbon Dioxide; Equipment Design; Glutathione; Hydrogen-Ion Concentration; Ilium; Insulin; Intestinal Mucosa; Lactic Acid; Male; Organ Preservation; Organ Preservation Solutions; Osmolar Concentration; Oxygen; Partial Pressure; Permeability; Raffinose; Rats; Rats, Sprague-Dawley; Time Factors; Transplants | 2007 |
Brain metabolism dictates the polarity of astrocyte control over arterioles.
Topics: Adenosine; Animals; Arterioles; Astrocytes; Brain; Dinoprostone; Glycolysis; Lactic Acid; Male; Organic Anion Transporters; Oxygen; Pressure; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasodilation; Vasodilator Agents | 2008 |
Fabrication via a nonaqueous nanoprecipitation method, characterization and in vitro biological behavior of N(6)-cyclopentyladenosine-loaded nanoparticles.
Topics: Adenosine; Cell Line; Chemistry, Pharmaceutical; Drug Carriers; Drug Compounding; Fractional Precipitation; Humans; Lactic Acid; Molecular Structure; Molecular Weight; Nanoparticles; Nanostructures; Nanotechnology; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solubility; Technology, Pharmaceutical | 2009 |
Sinefungin-PLGA nanoparticles: drug loading, characterization, in vitro drug release and in vivo studies.
Topics: Adenosine; Animals; Delayed-Action Preparations; Drug Compounding; Lactic Acid; Male; Materials Testing; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Wistar | 2009 |
Supplementation of University of Wisconsin solution with Nitroglycerin and Nicorandil in long-term myocardial preservation: effects on the oxidative state, endothelial function and morphology.
Topics: Adenosine; Allopurinol; Animals; Antioxidants; Calcium; Carbon Dioxide; Creatine Kinase; Endothelin-1; Endothelium; Fluorescent Antibody Technique, Indirect; Glucose; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Heart Transplantation; Heart Ventricles; Hydrogen-Ion Concentration; Immunohistochemistry; Insulin; L-Lactate Dehydrogenase; Lactic Acid; Malondialdehyde; Myocardium; Nicorandil; Nitrites; Nitroglycerin; Organ Preservation; Organ Preservation Solutions; Oxygen; Pharmaceutical Solutions; Raffinose; Random Allocation; Swine; Time Factors; Vasodilator Agents | 2009 |
Ischaemic preconditioning is related to decreasing levels of extracellular adenosine that may be metabolically useful in the at-risk myocardium: an experimental study in the pig.
Topics: 5'-Nucleotidase; Adenosine; Adenosine Triphosphate; Animals; Female; Humans; Ischemic Preconditioning, Myocardial; Lactic Acid; Microdialysis; Myocardial Ischemia; Myocardium; Swine | 2010 |
A role of erythrocytes in adenosine monophosphate initiation of hypometabolism in mammals.
Topics: 2,3-Diphosphoglycerate; Adenine Nucleotides; Adenosine; Adenosine Monophosphate; Animals; Chromatography, High Pressure Liquid; Erythrocytes; Female; Hibernation; Kinetics; Lactic Acid; Mammals; Metabolic Diseases; Metabolome; Mice; Mice, Inbred C57BL; Oxygen Consumption; Temperature | 2010 |
Early reperfusion with warm, polarizing adenosine-lidocaine cardioplegia improves functional recovery after 6 hours of cold static storage.
Topics: Adenosine; Adenosine Triphosphate; Animals; Aorta; Blood Pressure; Cardiac Output; Cardioplegic Solutions; Cold Ischemia; Coronary Circulation; Disaccharides; Electrolytes; Glutamates; Glutathione; Heart Arrest, Induced; Heart Rate; Heart Transplantation; Histidine; Hydrogen-Ion Concentration; Lactic Acid; Lidocaine; Male; Mannitol; Myocardial Reperfusion Injury; Myocardium; Oxygen Consumption; Perfusion; Rats; Rats, Sprague-Dawley; Recovery of Function; Regional Blood Flow; Time Factors; Warm Ischemia | 2011 |
Metabolic regulation of coronary vascular tone: role of hydrogen peroxide, purinergic components, and angiotensin.
Topics: Adenosine; Adenosine Diphosphate; Angiotensin Receptor Antagonists; Angiotensins; Animals; Arterioles; Catalase; Coronary Vessels; Hydrogen Peroxide; Imidazoles; In Vitro Techniques; Lactic Acid; Male; Myocytes, Cardiac; Oxygen; Purinergic P1 Receptor Antagonists; Purinergic P2Y Receptor Antagonists; Rats; Rats, Wistar; Superoxides; Tetrazoles; Theophylline; Vascular Resistance; Vasoconstriction; Vasodilation | 2010 |
Ischaemic pre-conditioning means an increased adenosine metabolism with decreased glycolytic flow in ischaemic pig myocardium.
Topics: Adenosine; Animals; Blood Glucose; Body Temperature; Energy Metabolism; Female; Glycerol; Glycogen; Glycolysis; Hemodynamics; Ischemic Preconditioning, Myocardial; Lactic Acid; Microdialysis; Myocardial Ischemia; Swine; Taurine | 2010 |
Shedding of the coronary endothelial glycocalyx: effects of hypoxia/reoxygenation vs ischaemia/reperfusion.
Topics: Adenosine; Analysis of Variance; Animals; Coronary Vessels; Endothelium, Vascular; Glycocalyx; Guinea Pigs; Heparitin Sulfate; Histamine; Hypoxia; Inosine; Ischemia; Lactic Acid; Male; Microcirculation; Microscopy, Electron; Purines; Reperfusion; Syndecan-1; Tryptases | 2011 |
Hypothermic machine perfusion of the liver: is it more complex than for the kidney?
Topics: Adenosine; Allopurinol; Animals; Endothelial Cells; Gene Expression Regulation; Glutathione; Hepatic Artery; Hydrogen-Ion Concentration; Insulin; Kidney Transplantation; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Kupffer Cells; Lactic Acid; Liver; Liver Transplantation; Models, Animal; Organ Preservation; Organ Preservation Solutions; Perfusion; Phenotype; Portal Vein; Raffinose; Swine | 2011 |
Metabolic characteristics of human hearts preserved for 12 hours by static storage, antegrade perfusion, or retrograde coronary sinus perfusion.
Topics: Adenosine; Adult; Allopurinol; Cold Temperature; Energy Metabolism; Female; Glutathione; Heart Transplantation; Heart Ventricles; Humans; Insulin; Lactic Acid; Male; Middle Aged; Myocardium; Organ Preservation; Organ Preservation Solutions; Oxygen Consumption; Perfusion; Proton Magnetic Resonance Spectroscopy; Raffinose; Time Factors; Water | 2014 |
Cholinergic neurons of the basal forebrain mediate biochemical and electrophysiological mechanisms underlying sleep homeostasis.
Topics: Adenosine; Animals; Antibodies, Monoclonal; Basal Forebrain; Cholinergic Neurons; Delta Rhythm; Homeostasis; Lactic Acid; Male; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitrites; Nitroso Compounds; Pyruvic Acid; Rats, Wistar; Ribosome Inactivating Proteins, Type 1; Saporins; Sleep; Sleep Deprivation; Theta Rhythm | 2015 |
Perfusion of isolated rat kidney with Mesenchymal Stromal Cells/Extracellular Vesicles prevents ischaemic injury.
Topics: Adenosine; Allopurinol; Animals; Biomarkers; Energy Metabolism; Extracellular Vesicles; Gene Expression; Gene Expression Profiling; Glucose; Glutathione; Insulin; Ion Transport; Kidney; Kidney Transplantation; L-Lactate Dehydrogenase; Lactic Acid; Malondialdehyde; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Organ Preservation; Organ Preservation Solutions; Perfusion; Pyruvic Acid; Raffinose; Rats; Rats, Inbred F344; Rats, Transgenic; Reperfusion Injury | 2017 |
Impact of human-derived hemoglobin based oxygen vesicles as a machine perfusion solution for liver donation after cardiac death in a pig model.
Topics: Adenosine; Allopurinol; Animals; Aspartate Aminotransferases; Female; Glutathione; Hemoglobins; Hepatic Artery; Humans; Hydrogen-Ion Concentration; Insulin; Lactic Acid; Liver; Liver Transplantation; Mitochondria; Models, Animal; Organ Preservation; Organ Preservation Solutions; Oxygen; Oxygen Consumption; Raffinose; Swine; Temperature | 2019 |
Polydopamine-assisted one-step modification of nanofiber surfaces with adenosine to tune the osteogenic differentiation of mesenchymal stem cells and the maturation of osteoclasts.
Topics: Adenosine; Animals; Cell Differentiation; Cells, Cultured; Humans; Indoles; Lactic Acid; Mesenchymal Stem Cells; Mice; Molecular Structure; Nanofibers; Osteoclasts; Osteogenesis; Particle Size; Polymers; RAW 264.7 Cells; Surface Properties | 2020 |
Adenosine, Lidocaine, and Magnesium Support a High Flow, Hypotensive, Vasodilatory State With Improved Oxygen Delivery and Cerebral Protection in a Pig Model of Noncompressible Hemorrhage.
Topics: Adenosine; Animals; Brain; Brain Chemistry; Disease Models, Animal; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluid Therapy; Glycerol; Humans; Hypotension; Hypoxia-Inducible Factor 1, alpha Subunit; Hypoxia, Brain; Infusions, Intravenous; Injections, Intravenous; Lactic Acid; Lidocaine; Liver; Magnesium; Oxygen; Resuscitation; Shock, Hemorrhagic; Stroke Volume; Sus scrofa; Vascular Resistance; Vasodilation | 2020 |
Species-dependent patterns of incorporation of purine mononucleotides and nucleosides by lactic acid bacteria.
Topics: Adenosine; Adenosine Monophosphate; Bacteria; Biological Transport; Lactic Acid; Species Specificity | 2020 |
Reversing Hypoxia with PLGA-Encapsulated Manganese Dioxide Nanoparticles Improves Natural Killer Cell Response to Tumor Spheroids.
Topics: Adaptive Immunity; Adenosine; Adoptive Transfer; Breast Neoplasms; Cell Hypoxia; Female; Humans; Hydrogen Peroxide; Immune Tolerance; Killer Cells, Natural; Lactic Acid; Manganese Compounds; MCF-7 Cells; Metal Nanoparticles; Nanocapsules; Oxides; Particle Size; Polylactic Acid-Polyglycolic Acid Copolymer; Signal Transduction; Spheroids, Cellular; Tumor Microenvironment | 2021 |
Combatting ischemia reperfusion injury from resuscitative endovascular balloon occlusion of the aorta using adenosine, lidocaine and magnesium: A pilot study.
Topics: Adenosine; Animals; Anti-Inflammatory Agents; Aorta; Balloon Occlusion; Disease Models, Animal; Drug Therapy, Combination; Endovascular Procedures; Hydrogen-Ion Concentration; Lactic Acid; Lidocaine; Magnesium; Protective Agents; Reperfusion Injury; Resuscitation; Shock, Hemorrhagic; Swine; Treatment Outcome | 2021 |
A Sub-6 nm MnFe
Topics: Adenosine; Adenosine Triphosphate; Cell Line, Tumor; Dichloroacetic Acid; Glucose; Immunosuppressive Agents; Immunotherapy; Lactic Acid; Nanocomposites; Tumor Microenvironment | 2022 |