lactic acid has been researched along with acetylcysteine in 32 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (12.50) | 18.7374 |
| 1990's | 3 (9.38) | 18.2507 |
| 2000's | 7 (21.88) | 29.6817 |
| 2010's | 17 (53.13) | 24.3611 |
| 2020's | 1 (3.13) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Buckley, BM; Gray, TA; Vale, JA | 1 |
| Weber, AL | 3 |
| Arnold, DL; De Stefano, N; Ford, B; Genge, A; Karpati, G; Matthews, PM | 1 |
| Aalbers, T; Commandeur, JN; de Rooij, BM; Groot, EJ; Hommes, JW; Vermeulen, NP | 1 |
| Demanet, C; Huyghens, L; Spapen, H; Vincent, JL; Vleminckx, W; Zhang, H | 1 |
| Jongsakul, K; Ruangvirayuth, R; Watt, G | 1 |
| Carbonell, LF; Cuevas, S; Díaz, J; Fenoy, F; Hernández, I; Quesada, T; Salom, MG; Valero, F | 1 |
| Bagshaw, SM; Bellomo, R; Buxton, B; Doolan, L; Haase, M; Haase-Fielitz, A; Matalanis, G; Morgera, S; Reade, MC; Seevenayagam, S | 1 |
| Desai, KG; Mallery, SR; Schwendeman, SP | 1 |
| Bhattacharya, R; Hariharakrishnan, J; Satpute, RM | 1 |
| Gerelchuluun, T; Han, K; Im, SA; Kim, K; Lee, CK; Lee, YH; Lee, YR; Park, JS; Song, S | 1 |
| Cekic, B; Coskun, I; Eroglu, A; Erturk, E; Geze, S; Karahan, C; Kerimoglu, S; Kosucu, M; Mentese, A; Ulusoy, H | 1 |
| Garnham, AP; Hargreaves, M; McConell, GK; Merry, TL; Rattigan, S; Stathis, CG; Wadley, GD | 1 |
| Khansuwan, R; Klaphajone, J; Leelarungrayub, D; Pothongsunun, P | 1 |
| Cuenod, M; das Neves Duarte, JM; Do, KQ; Gholam-Razaee, MM; Gruetter, R; Kulak, A | 1 |
| Björnsson, B; Bojmar, L; Gullstrand, P; Sandström, P; Sundqvist, T; Trulsson, L; Winbladh, A | 1 |
| Chou, YC; Guengerich, FP; Huang, C; Kao, FJ; Lai, PS; Lee, HC; Mazumder, N; Nagy, LD; Ueng, YF; Wang, SF | 1 |
| Amezquita, LV; Briceno, JF; Bruton, JD; Caballero, DM; Hernández, A; Katz, A; Kosterina, N; Westerblad, H | 1 |
| Billaut, F; McInerney, BV; McQuade, LR; Petersen, AC; Stepto, NK; Trewin, AJ | 1 |
| Abbasi, S; Amani, A; Faramarzi, MA; Ghazi-Khansari, M; Gilani, K; Karimi Zarchi, AA | 1 |
| Ghannoum, M; Gosselin, S; Grunbaum, AM; Kazim, S; Villeneuve, E | 1 |
| Alqathama, A; Elsaid, N; Elsaid, Z; Jackson, TL; Somavarapu, S | 1 |
| Lampe, KJ; Murphy, NP | 1 |
| Ito, Y; Kimura, M; Kojima, W; Koyano, F; Matsuda, N; Mishima, M; Mizushima, T; Queliconi, BB; Takagi, K; Tanaka, K; Yamano, K | 1 |
| Constantino, L; da Silva, LA; Dal-Pizzol, F; Dall'Igna, DM; de Medeiros, WA; Dos Santos Cardoso, J; Manfredini, A; Michels, M; Ritter, C; Scaini, G; Streck, EL; Vuolo, F | 1 |
| Abdenur, JE; Boyer, M; Di Meo, I; Eftekharian, S; Sowa, M; Steenari, MR; Tiranti, V | 1 |
| Akarsu Ayazoğlu, T; Günay, M; Onk, D; Onk, OA; Özçelik, F; Ünver, E | 1 |
| Bauzá-Thorbrügge, M; Enejder, A; Micallef, P; Olofsson, CS; Palsdottir, V; Paul, A; Peris, E; Wernstedt Asterholm, I | 1 |
| Kim, SY; Lee, JH; Subedi, L | 1 |
9 trial(s) available for lactic acid and acetylcysteine
| Article | Year |
|---|---|
Short-term dichloroacetate treatment improves indices of cerebral metabolism in patients with mitochondrial disorders.
Topics: Acetylcysteine; Adenosine Diphosphate; Adolescent; Adult; Aged; Alanine; Brain; Child; Creatine; Cross-Over Studies; Dichloroacetic Acid; Double-Blind Method; Female; Humans; Lactates; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Middle Aged; Mitochondrial Myopathies; Placebos; Pyruvate Dehydrogenase Complex | 1995 |
Does N-acetyl-L-cysteine influence cytokine response during early human septic shock?
Topics: Acetylcysteine; Adult; Aged; Aged, 80 and over; Antigens, CD; Double-Blind Method; Female; Hemodynamics; Humans; Infusions, Intravenous; Interleukin-10; Interleukin-6; Interleukin-8; Interleukins; Lactic Acid; Lung Compliance; Male; Middle Aged; Oxygen Consumption; Prospective Studies; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Shock, Septic; Tumor Necrosis Factor-alpha | 1998 |
A pilot study of N-acetylcysteine as adjunctive therapy for severe malaria.
Topics: Acetylcysteine; Adjuvants, Pharmaceutic; Adult; Antimalarials; Double-Blind Method; Humans; Interferon-gamma; Interleukin-10; Interleukin-6; Lactic Acid; Malaria; Male; Pilot Projects; Prospective Studies; Quinine; Statistics, Nonparametric; Time Factors; Tumor Necrosis Factor-alpha | 2002 |
Phase II, randomized, controlled trial of high-dose N-acetylcysteine in high-risk cardiac surgery patients.
Topics: Acetylcysteine; Acute Kidney Injury; Aged; Blood Pressure; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Creatinine; Female; Free Radical Scavengers; Humans; Kidney; Lactic Acid; Male; Premedication; Preoperative Care; Treatment Outcome | 2007 |
Comparison of the effect of propofol and N-acetyl cysteine in preventing ischaemia-reperfusion injury.
Topics: Acetylcysteine; Adolescent; Adult; Aged; Anesthesia, Spinal; Anesthetics, Intravenous; Blood Gas Analysis; Double-Blind Method; Female; Humans; Lactic Acid; Male; Malondialdehyde; Middle Aged; Propofol; Prospective Studies; Reperfusion Injury; Tourniquets; Treatment Outcome; Young Adult | 2009 |
N-Acetylcysteine infusion does not affect glucose disposal during prolonged moderate-intensity exercise in humans.
Topics: Acetylcysteine; Adult; AMP-Activated Protein Kinase Kinases; Anaerobic Threshold; Cross-Over Studies; Cysteine; Cystine; Double-Blind Method; Exercise; Exercise Test; Fatty Acids, Nonesterified; Free Radical Scavengers; Glucose; Glutathione; Heart Rate; Humans; Infusions, Intravenous; Lactic Acid; Male; Muscle, Skeletal; Protein Kinases; Reactive Oxygen Species; Signal Transduction; Young Adult | 2010 |
N-acetylcysteine supplementation controls total antioxidant capacity, creatine kinase, lactate, and tumor necrotic factor-alpha against oxidative stress induced by graded exercise in sedentary men.
Topics: Acetylcysteine; Adult; Antioxidants; Creatine Kinase; Exercise; Humans; Lactic Acid; Male; Muscle, Skeletal; Oxidative Stress; Tumor Necrosis Factor-alpha; Young Adult | 2011 |
N-acetylcysteine alters substrate metabolism during high-intensity cycle exercise in well-trained humans.
Topics: Acetylcysteine; Blood Glucose; Double-Blind Method; Exercise; Exercise Test; Humans; Lactic Acid | 2013 |
Assessment of Renal and Hepatic Tissue-Protective Effects of N-Acetylcysteine via Ammonia Metabolism: A Prospective Randomized Study.
Topics: Acetylcysteine; Adult; Ammonia; Blood Urea Nitrogen; Female; Humans; Kidney; Lactic Acid; Liver; Male | 2018 |
23 other study(ies) available for lactic acid and acetylcysteine
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Hyperlactataemia and metabolic acidosis following paracetamol overdose.
Topics: Acetaminophen; Acetylcysteine; Acidosis, Lactic; Adolescent; Adult; Aged; Aged, 80 and over; Female; Humans; Lactates; Lactic Acid; Liver; Male; Middle Aged; Prospective Studies; Suicide, Attempted; Time Factors | 1987 |
Thiol-catalyzed formation of lactate and glycerate from glyceraldehyde.
Topics: Acetylcysteine; Carbon Radioisotopes; Carboxylic Acids; Chemical Phenomena; Chemistry; Glyceraldehyde; Glyceric Acids; Kinetics; Lactates; Lactic Acid; Monosaccharides | 1983 |
Urinary metabolite profile of phenyl and o-cresyl glycidyl ether in rats: identification of a novel pathway leading to N-acetylserine O-conjugates.
Topics: Acetylcysteine; Animals; Biomarkers; Dose-Response Relationship, Drug; Epoxy Compounds; Glutathione; Kinetics; Lactic Acid; Male; Occupational Exposure; Rats; Rats, Wistar; Serine; Structure-Activity Relationship | 1998 |
Prebiotic formation of 'energy-rich' thioesters from glyceraldehyde and N-acetylcysteine.
Topics: Acetylcysteine; Biopolymers; Evolution, Chemical; Glyceraldehyde; Imidazoles; Lactic Acid; Origin of Life; Phosphates; Phosphorylation; Sulfhydryl Compounds | 1984 |
Alanine synthesis from glyceraldehyde and ammonium ion in aqueous solution.
Topics: Acetylcysteine; Alanine; Evolution, Chemical; Evolution, Molecular; Formates; Glyceraldehyde; Glycine; Glycolates; Lactic Acid; Quaternary Ammonium Compounds; Serine; Sulfhydryl Compounds | 1985 |
N-acetylcysteine exerts protective effects and prevents lung redox imbalance and peroxynitrite generation in endotoxemic rats.
Topics: Acetylcysteine; Animals; Coloring Agents; Endotoxemia; Enzyme Inhibitors; Free Radical Scavengers; Lactic Acid; Lipopolysaccharides; Lung; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Oxidation-Reduction; Peroxynitrous Acid; Platelet Count; Rats; Rats, Wistar; Rhodamines; Sulfhydryl Compounds; Thiobarbituric Acid Reactive Substances | 2007 |
Formulation and characterization of injectable poly(DL-lactide-co-glycolide) implants loaded with N-acetylcysteine, a MMP inhibitor.
Topics: Acetylcysteine; Animals; Antineoplastic Agents; Calcium Compounds; Calorimetry, Differential Scanning; Catalysis; Chemistry, Pharmaceutical; Drug Carriers; Drug Compounding; Drug Implants; Drug Stability; Head and Neck Neoplasms; Humans; Injections; Kinetics; Lactic Acid; Magnesium Compounds; Matrix Metalloproteinase Inhibitors; Microscopy, Electron, Scanning; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Protease Inhibitors; Solubility; Technology, Pharmaceutical; X-Ray Diffraction | 2008 |
Alpha-ketoglutarate and N-acetyl cysteine protect PC12 cells from cyanide-induced cytotoxicity and altered energy metabolism.
Topics: Acetylcysteine; Animals; Calcium; Cell Survival; Cyanates; Dose-Response Relationship, Drug; Drug Interactions; Energy Metabolism; Free Radical Scavengers; Ketoglutaric Acids; Lactic Acid; PC12 Cells; Peroxides; Rats; Time Factors | 2008 |
Dendritic cells process antigens encapsulated in a biodegradable polymer, poly(D,L-lactide-co-glycolide), via an alternate class I MHC processing pathway.
Topics: Acetylcysteine; Antigen Presentation; ATP Binding Cassette Transporter, Subfamily B, Member 2; ATP-Binding Cassette Transporters; Brefeldin A; Cell Line; Chloroquine; Dendritic Cells; Histocompatibility Antigens Class I; Humans; Lactic Acid; Nanospheres; Ovalbumin; Phagocytosis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers | 2007 |
N-acetylcysteine normalizes neurochemical changes in the glutathione-deficient schizophrenia mouse model during development.
Topics: Acetylcysteine; Alanine; Animals; Aspartic Acid; Cerebral Cortex; Disease Models, Animal; Free Radical Scavengers; Glutamate-Cysteine Ligase; Glutamic Acid; Glutamine; Glutathione; Inositol; Lactic Acid; Longitudinal Studies; Magnetic Resonance Spectroscopy; Mice; Mice, Knockout; Schizophrenia | 2012 |
N-acetyl cysteine improves glycogenesis after segmental liver ischemia and reperfusion injury in pigs.
Topics: Acetylcysteine; Adenosine Triphosphate; Analysis of Variance; Animals; Apoptosis; Aspartate Aminotransferases; Free Radical Scavengers; Glutathione; Glycogen; Lactic Acid; Leukocyte Count; Liver; Male; Microdialysis; Neutrophils; Nitrates; Nitrites; Reperfusion Injury; Swine | 2012 |
7-Ketocholesterol induces P-glycoprotein through PI3K/mTOR signaling in hepatoma cells.
Topics: Acetylcysteine; Antibiotics, Antineoplastic; Antioxidants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carcinoma, Hepatocellular; Cell Line; Cell Line, Tumor; Cell Survival; Cholesterol; Doxorubicin; Drug Resistance, Neoplasm; Hepatocytes; Humans; Hydroxycholesterols; Ketocholesterols; Lactic Acid; Oligomycins; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Signal Transduction; TOR Serine-Threonine Kinases; Up-Regulation | 2013 |
Effects of N-acetylcysteine on isolated mouse skeletal muscle: contractile properties, temperature dependence, and metabolism.
Topics: Acetylcysteine; Animals; Antioxidants; Female; Hot Temperature; Isometric Contraction; Lactic Acid; Malates; Mice; Mice, Inbred C57BL; Muscle Relaxation; Muscle, Skeletal; Myosin Light Chains; Phosphates; Phosphorylation | 2014 |
Development and optimization of N-Acetylcysteine-loaded poly (lactic-co-glycolic acid) nanoparticles by electrospray.
Topics: Acetylcysteine; Chemistry, Pharmaceutical; Drug Carriers; Drug Stability; Humans; Lactic Acid; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers | 2015 |
Massive acetaminophen overdose: effect of hemodialysis on acetaminophen and acetylcysteine kinetics.
Topics: Acetaminophen; Acetylcysteine; Acidosis, Lactic; Adolescent; Coma; Drug Overdose; Emergency Service, Hospital; Ethanol; Female; Half-Life; Humans; Ibuprofen; Lactic Acid; Liver; Renal Dialysis | 2016 |
PLGA Microparticles Entrapping Chitosan-Based Nanoparticles for the Ocular Delivery of Ranibizumab.
Topics: Acetylcysteine; Cell Line; Cell Movement; Cell Survival; Chitosan; Drug Delivery Systems; Human Umbilical Vein Endothelial Cells; Humans; Hyaluronic Acid; Lactic Acid; Macular Degeneration; Magnetic Resonance Spectroscopy; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polyphosphates; Ranibizumab; Spectroscopy, Fourier Transform Infrared | 2016 |
Fabricating PLGA microparticles with high loads of the small molecule antioxidant N-acetylcysteine that rescue oligodendrocyte progenitor cells from oxidative stress.
Topics: Acetylcysteine; Animals; Antioxidants; Biocompatible Materials; Cell Survival; Cells, Cultured; Drug Carriers; Lactic Acid; Mice; Oligodendrocyte Precursor Cells; Oxidative Stress; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2018 |
Parkinson's disease-related DJ-1 functions in thiol quality control against aldehyde attack in vitro.
Topics: Acetylcysteine; Aldehydes; Amino Acid Sequence; beta-Alanine; Coenzyme A; Glutathione; HeLa Cells; Humans; Inactivation, Metabolic; Lactic Acid; Mutant Proteins; Mutation; Parkinson Disease; Protein Deglycase DJ-1; Pyruvaldehyde; Recombinant Proteins; Sequence Homology, Amino Acid; Structural Homology, Protein; Sulfhydryl Compounds | 2017 |
N-acetylcysteine effects on a murine model of chronic critical limb ischemia.
Topics: Acetylcysteine; Animals; Disease Models, Animal; Hindlimb; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Inflammation; Interleukin-6; Ischemia; Lactic Acid; Male; Muscle, Skeletal; Nitrates; Nitrites; Oxidative Stress; Oxygen; Oxygen Consumption; Peroxidase; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances; Vascular Endothelial Growth Factor A | 2018 |
Response to medical and a novel dietary treatment in newborn screen identified patients with ethylmalonic encephalopathy.
Topics: Acetylcysteine; Amino Acids; Biomarkers; Brain Diseases, Metabolic, Inborn; Cysteine; Diet; Female; Humans; Infant; Infant, Newborn; Lactic Acid; Male; Malonates; Methionine; Metronidazole; Mitochondrial Proteins; Mutation; Neonatal Screening; Nucleocytoplasmic Transport Proteins; Purpura; Sulfur | 2018 |
Antioxidant treatment induces reductive stress associated with mitochondrial dysfunction in adipocytes.
Topics: 3T3-L1 Cells; Acetylcysteine; Adipocytes, Brown; Animals; Antioxidants; Lactic Acid; Male; Mice; Mitochondria; Oxidative Stress; Reactive Oxygen Species; Receptors, Adrenergic, beta-3 | 2019 |
Effect of Cysteine on Methylglyoxal-Induced Renal Damage in Mesangial Cells.
Topics: Acetylcysteine; Animals; Apoptosis; Cell Line; Cell Survival; Cysteine; Guanidines; Humans; L-Lactate Dehydrogenase; Lactic Acid; Lactoylglutathione Lyase; MAP Kinase Signaling System; Mesangial Cells; Mice; Pyruvaldehyde; Reactive Oxygen Species; Sirtuin 1 | 2020 |