lactic acid has been researched along with 1-methyl-4-phenylpyridinium in 19 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (15.79) | 18.7374 |
| 1990's | 7 (36.84) | 18.2507 |
| 2000's | 5 (26.32) | 29.6817 |
| 2010's | 3 (15.79) | 24.3611 |
| 2020's | 1 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Beal, MF; Brouillet, E; Hyman, BT; Jenkins, B; Miller, JM; Rosen, BR; Storey, E | 1 |
| Basma, AN; Geller, HM; Heikkila, RE; Nicklas, WJ; Philbert, M; Saporito, MS | 1 |
| Carmichael, SW; Daniels, AJ; Reinhard, JF | 1 |
| Booth, RG; Caldera, P; Castagnoli, N; Johnson, EA; Lampen, P; Naiman, N; Rollema, H; Trevor, AJ; Youngster, SK | 1 |
| De Vries, J; Kranenborg, G; Kuhr, WG; Rollema, H; Van den Berg, C | 1 |
| Damsma, G; de Vries, JB; Horn, AS; Kranenborg, GL; Kuhr, WG; Rollema, H; Westerink, BH | 1 |
| Heikkila, RE; Kindt, MV; Nicklas, WJ | 1 |
| Castagnoli, N; D'Engelbronner, J; Igarashi, K; Rollema, H; Skolnik, M; Usuki, E | 1 |
| Samuelsson, EB; Sundström, E | 1 |
| Bennett, JP; Fall, CP | 1 |
| Marini, AM; Nowak, TS | 1 |
| Awaya, T; Chiba, K; Hayase, N; Kimura, K; Matsubara, K; Ogawa, S; Senda, T; Shimizu, K; Uezono, T | 1 |
| Alonso, JC; Fuentes, JM; González-Polo, RA; Rodríguez-Martín, A; Soler, G | 1 |
| Mazzio, E; Soliman, KF; Yoon, KJ | 1 |
| Gille, G; Radad, K; Rausch, WD; Reichmann, H | 1 |
| Mazzio, E; Soliman, KF | 1 |
| Chaudhuri, AD; Choi, DC; Junn, E; Kabaria, S; Mouradian, MM | 1 |
| Bezard, E; Blanchard-Desce, M; Bourdenx, M; Daniel, J; Dehay, B; Genin, E; Soria, FN | 1 |
| Blasco-Agell, L; Ferigle, L; Rabaneda-Lombarte, N; Saura, J; Serratosa, J; Solà, C | 1 |
19 other study(ies) available for lactic acid and 1-methyl-4-phenylpyridinium
| Article | Year |
|---|---|
1-Methyl-4-phenylpyridinium produces excitotoxic lesions in rat striatum as a result of impairment of oxidative metabolism.
Topics: 1-Methyl-4-phenylpyridinium; Adenosine Triphosphate; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Dose-Response Relationship, Drug; Electrochemistry; Energy Metabolism; Lactates; Lactic Acid; Male; N-Methylaspartate; Neurotoxins; Oxidation-Reduction; Rats; Rats, Inbred Strains | 1992 |
1-Methyl-4-(2'-ethylphenyl)-1,2,3,6-tetrahydropyridine-induced toxicity in PC12 cells is enhanced by preventing glycolysis.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Glucose; Glycolysis; Lactates; Lactic Acid; PC12 Cells; Rotenone; Time Factors | 1992 |
Mechanisms of toxicity and cellular resistance to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 1-methyl-4-phenylpyridinium in adrenomedullary chromaffin cell cultures.
Topics: 1-Methyl-4-phenylpyridinium; Adrenal Medulla; Animals; Cell Survival; Cells, Cultured; Chromaffin System; Glucose; Lactates; Lactic Acid; MPTP Poisoning; Tyrosine 3-Monooxygenase | 1990 |
In vivo intracerebral microdialysis studies in rats of MPP+ analogues and related charged species.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Brain; Chemical Phenomena; Chemistry; Corpus Striatum; Dialysis; Dopamine; Kinetics; Lactates; Lactic Acid; Male; Molecular Structure; MPTP Poisoning; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1990 |
MPP+-induced efflux of dopamine and lactate from rat striatum have similar time courses as shown by in vivo brain dialysis.
Topics: 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dialysis; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Lactates; Lactic Acid; Male; Pyridinium Compounds; Rats; Rats, Inbred Strains; Time Factors | 1988 |
The use of in vivo brain dialysis of dopamine, acetylcholine, amino acids and lactic acid in studies on the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 2,4-Dinitrophenol; Acetylcholine; Amino Acids; Amphetamine; Animals; Brain; Dialysis; Dinitrophenols; Dopamine; Lactates; Lactic Acid; Pyridines; Pyridinium Compounds; Rats | 1988 |
Mitochondrial and metabolic toxicity of 1-methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Allylamine; Animals; Brain; Corpus Striatum; Dose-Response Relationship, Drug; In Vitro Techniques; Lactates; Lactic Acid; Male; Mice; Mice, Inbred C57BL; Mitochondria; Pyridines; Pyridinium Compounds | 1987 |
MPP(+)-like neurotoxicity of a pyridinium metabolite derived from haloperidol: in vivo microdialysis and in vitro mitochondrial studies.
Topics: 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Dopamine; Haloperidol; Lactates; Lactic Acid; Male; Mice; Microdialysis; Mitochondria, Liver; Nervous System; Pyridinium Compounds; Rats; Rats, Wistar; Receptors, Dopamine; Receptors, Serotonin; Serotonin | 1994 |
Comparison of key steps in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxicity in rodents.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Brain; Dopamine; Lactic Acid; Male; Mice; Mice, Inbred C57BL; MPTP Poisoning; Norepinephrine; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Synaptosomes | 1997 |
Characterization and time course of MPP+ -induced apoptosis in human SH-SY5Y neuroblastoma cells.
Topics: 1-Methyl-4-phenylpyridinium; Apoptosis; Cell Cycle; Cell Membrane; Cell Nucleus; DNA Fragmentation; Dose-Response Relationship, Drug; Electron Transport; Flow Cytometry; Fluoresceins; Humans; Lactic Acid; Membrane Potentials; Microscopy, Electron, Scanning; Mitochondria; NAD(P)H Dehydrogenase (Quinone); Neuroblastoma; Neurons; Reactive Oxygen Species; Rhodamines; Time Factors; Tumor Cells, Cultured | 1999 |
Metabolic effects of 1-methyl-4-phenylpyridinium (MPP(+)) in primary neuron cultures.
Topics: 1-Methyl-4-phenylpyridinium; Adenosine Triphosphate; Animals; Cells, Cultured; Cerebellum; Glucose; Herbicides; Lactic Acid; Neurons; Phosphocreatine; Rats | 2000 |
L-Deprenyl prevents the cell hypoxia induced by dopaminergic neurotoxins, MPP(+) and beta-carbolinium: a microdialysis study in rats.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Carbolines; Cell Hypoxia; Dopamine; Dose-Response Relationship, Drug; Extracellular Space; Herbicides; Lactic Acid; Male; Microdialysis; Mitochondria; Monoamine Oxidase Inhibitors; Neostriatum; Neurons; Neuroprotective Agents; Neurotoxins; Pargyline; Parkinson Disease; Rats; Rats, Wistar; Selegiline | 2001 |
MPP(+) causes inhibition of cellular energy supply in cerebellar granule cells.
Topics: 1-Methyl-4-phenylpyridinium; Adenosine Triphosphate; Animals; Cell Survival; Cells, Cultured; Cerebellum; Cytoplasmic Granules; Dopamine Agents; Dose-Response Relationship, Drug; Energy Metabolism; Female; Glucose; Glycolysis; Lactic Acid; Male; Mitochondria; NAD; Neurons; Nucleotides; Rats; Rats, Wistar | 2003 |
Acetyl-L-carnitine cytoprotection against 1-methyl-4-phenylpyridinium toxicity in neuroblastoma cells.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Acetylcarnitine; Adenosine Triphosphate; Animals; Cell Survival; Cytoprotection; Drug Interactions; Glucose; Lactic Acid; Mice; Neuroblastoma; Oxygen Consumption; Protective Agents; Tumor Cells, Cultured | 2003 |
Synergistic effect of alpha-dihydroergocryptine and L-dopa or dopamine on dopaminergic neurons in primary culture.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Carbidopa; Cell Count; Cells, Cultured; Dihydroergocryptine; Dopamine; Dopamine Agents; Dopamine Antagonists; Drug Synergism; Female; Lactic Acid; Levodopa; Mice; Neuroglia; Neurons; Pregnancy; Sulpiride; Tyrosine 3-Monooxygenase | 2006 |
Whole genome expression profile in neuroblastoma cells exposed to 1-methyl-4-phenylpyridine.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Interactions; Gene Expression Regulation, Neoplastic; Genome; Glucose; Glycolysis; Herbicides; Lactic Acid; Mice; Neuroblastoma; Oxygen Consumption; RNA, Messenger; Signal Transduction; Time Factors; Transcriptome | 2012 |
MicroRNA-7 Promotes Glycolysis to Protect against 1-Methyl-4-phenylpyridinium-induced Cell Death.
Topics: 1-Methyl-4-phenylpyridinium; Adenosine Triphosphate; Animals; Cell Death; Cell Differentiation; Cell Line, Tumor; Cell Survival; Deoxyglucose; Glucose; Glucose Transporter Type 3; Glycolysis; HEK293 Cells; Humans; Lactic Acid; Mice; Mice, Inbred C57BL; MicroRNAs; Mitochondria; Neurons; Oxidative Phosphorylation; Oxygen; Parkinson Disease; Phosphorylation; Transcription Factor RelA | 2015 |
Nanoparticles restore lysosomal acidification defects: Implications for Parkinson and other lysosomal-related diseases.
Topics: 1-Methyl-4-phenylpyridinium; Acids; Alkalies; Animals; Cell Death; Dopaminergic Neurons; Humans; Hydrogen-Ion Concentration; Injections, Intraventricular; Lactic Acid; Lysosomal Storage Diseases; Lysosomes; Mice; Models, Biological; Models, Genetic; Nanoparticles; Neostriatum; Nerve Degeneration; Parkinson Disease; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer | 2016 |
Parkinsonian neurotoxicants impair the anti-inflammatory response induced by IL4 in glial cells: involvement of the CD200-CD200R1 ligand-receptor pair.
Topics: 1-Methyl-4-phenylpyridinium; Adenosine Triphosphate; Animals; Antigens, CD; Cells, Cultured; Female; Interleukin-4; Lactic Acid; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Microglia; Pesticides; Phagocytosis | 2020 |