lacosamide and 3-4-epoxy-1-butene

lacosamide has been researched along with 3-4-epoxy-1-butene* in 1 studies

Other Studies

1 other study(ies) available for lacosamide and 3-4-epoxy-1-butene

ArticleYear
An enantioselective approach to functionalized amino acids: total synthesis of antiepileptic drug (R)-lacosamide.
    The Journal of organic chemistry, 2015, Apr-17, Volume: 80, Issue:8

    A short and highly efficient synthetic approach to enantiopure functionalized amino acids (FAAs) 1 skeleton from racemic butadiene monoepoxide as a starting material and its application to the total synthesis of an antiepileptic drug (R)-lacosamide 2 are described. The synthesis utilizes the palladium catalyzed Trost's Dynamic Kinetic Asymmetric Transformation (DYKAT) as key step.

    Topics: Acetamides; Amino Acids; Anticonvulsants; Catalysis; Epoxy Compounds; Kinetics; Lacosamide; Molecular Structure; Stereoisomerism

2015