lacosamide has been researched along with 3-4-epoxy-1-butene* in 1 studies
1 other study(ies) available for lacosamide and 3-4-epoxy-1-butene
Article | Year |
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An enantioselective approach to functionalized amino acids: total synthesis of antiepileptic drug (R)-lacosamide.
A short and highly efficient synthetic approach to enantiopure functionalized amino acids (FAAs) 1 skeleton from racemic butadiene monoepoxide as a starting material and its application to the total synthesis of an antiepileptic drug (R)-lacosamide 2 are described. The synthesis utilizes the palladium catalyzed Trost's Dynamic Kinetic Asymmetric Transformation (DYKAT) as key step. Topics: Acetamides; Amino Acids; Anticonvulsants; Catalysis; Epoxy Compounds; Kinetics; Lacosamide; Molecular Structure; Stereoisomerism | 2015 |