labetalol and timolol

labetalol has been researched along with timolol in 37 studies

Research

Studies (37)

Timeframe	Studies, this research(%)	All Research%
pre-1990	15 (40.54)	18.7374
1990's	1 (2.70)	18.2507
2000's	12 (32.43)	29.6817
2010's	8 (21.62)	24.3611
2020's	1 (2.70)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Faller, B; Wohnsland, F	1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P	1
Baker, JG	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Campillo, NE; Guerra, A; Páez, JA	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U	1
Bellman, K; Knegtel, RM; Settimo, L	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Chang, Q; Chen, Z; Hu, G; Hu, L; Li, Q; Long, J	1
Wilcox, RG	1
Nencini, P	1
Leopold, IH; Murray, DL	1
Lund-Johansen, P	1
Baum, T; Cummins, DP; Glennon, J; Vander Vliet, G; Watkins, RW	1
Hosaka, A	1
Palkama, A; Raij, K; Uusitalo, H; Uusitalo, R	1
Fishbein, L; Jackson, CD	1
Maddox, YT; Mostaghim, R; Ramwell, PW	1
Frame, V; Lathers, CM; Roberts, J; Tumer, N	1
Proegler, M; Schneider, H	1
Seal, DV	1
Chung, DC; Laschuk, MJ	1
Hopkins, GA	1
Bellucci, R; Bonomi, L; Massa, F; Noya, E; Perfetti, S	1
Abuin, L; Cotecchia, S; Lattion, A; Nenniger-Tosato, M	1
Asadpour-Zeynali, K; Jouyban, A; Majidi, MR	1

Reviews

4 review(s) available for labetalol and timolol

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
A toxicological review of beta-adrenergic blockers. Fundamental and applied toxicology : official journal of the Society of Toxicology, 1986, Volume: 6, Issue:3 Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Atenolol; Cocarcinogenesis; Ethanolamines; Female; Kinetics; Labetalol; Lethal Dose 50; Male; Metoprolol; Mice; Mutagens; Nadolol; Neoplasms, Experimental; Oxprenolol; Pindolol; Practolol; Propanolamines; Propranolol; Rats; Sotalol; Timolol	1986
The new beta-adrenergic antagonists. Canadian Anaesthetists' Society journal, 1984, Volume: 31, Issue:4 Topics: Adrenergic beta-Antagonists; Atenolol; Humans; Labetalol; Metoprolol; Nadolol; Oxprenolol; Pindolol; Propanolamines; Timolol	1984
Drug treatment of glaucoma. American journal of optometry and physiological optics, 1984, Volume: 61, Issue:12 Topics: Acetazolamide; Administration, Topical; Adrenergic beta-Antagonists; Bromocriptine; Clonidine; Dronabinol; Epinephrine; Glaucoma; Humans; Labetalol; Miotics; Nadolol; Parasympathomimetics; Pilocarpine; Propanolamines; Sympathomimetics; Timolol	1984

Trials

2 trial(s) available for labetalol and timolol

Article	Year
Randomised study of six beta-blockers and a thiazide diuretic in essential hypertension. British medical journal, 1978, Aug-05, Volume: 2, Issue:6134 Topics: Acebutolol; Adrenergic beta-Antagonists; Adult; Atenolol; Bendroflumethiazide; Clinical Trials as Topic; Female; Humans; Hypertension; Labetalol; Male; Middle Aged; Pindolol; Propranolol; Random Allocation; Timolol	1978
Myopia prevention and therapy. The role of pharmaceutical agents. Japanese studies. Acta ophthalmologica. Supplement, 1988, Volume: 185 Topics: Adolescent; Child; Cyclopentolate; Humans; Labetalol; Myopia; Ophthalmic Solutions; Timolol; Tropicamide	1988

Other Studies

31 other study(ies) available for labetalol and timolol

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes. Journal of medicinal chemistry, 2001, Mar-15, Volume: 44, Issue:6 Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water	2001
Cheminformatic models to predict binding affinities to human serum albumin. Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25 Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids	2001
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability. Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7 Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties	2004
The selectivity of beta-adrenoceptor antagonists at the human beta1, beta2 and beta3 adrenoceptors. British journal of pharmacology, 2005, Volume: 144, Issue:3 Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Algorithms; Animals; Cell Line; CHO Cells; Cricetinae; Dioxoles; Humans; Propanolamines; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Receptors, Adrenergic, beta-3	2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19 Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR. European journal of medicinal chemistry, 2011, Volume: 46, Issue:1 Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics	2011
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1 Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests	2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds. Pharmaceutical research, 2014, Volume: 31, Issue:4 Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation	2014
Drug repurposing and rediscovery: Design, synthesis and preliminary biological evaluation of 1-arylamino-3-aryloxypropan-2-ols as anti-melanoma agents. Bioorganic & medicinal chemistry, 2020, 05-01, Volume: 28, Issue:9 Topics: Antineoplastic Agents; Apoptosis; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Discovery; Drug Repositioning; Drug Screening Assays, Antitumor; Humans; Melanoma; Molecular Docking Simulation; Molecular Structure; Propanols; Skin Neoplasms; Structure-Activity Relationship; Tumor Cells, Cultured	2020
The influence of calcium on the antilipolytic action of propranolol, timolol, labetalol, verapamil, procaine, and papaverine in rat adipocytes. Pharmacological research communications, 1979, Volume: 11, Issue:9 Topics: Adipose Tissue; Adrenergic beta-Antagonists; Adrenocorticotropic Hormone; Animals; Calcium; In Vitro Techniques; Isoproterenol; Labetalol; Lipolysis; Male; Papaverine; Procaine; Propranolol; Rats; Timolol; Vasodilator Agents; Verapamil	1979
Ocular hypotensive action of labetalol. American journal of ophthalmology, 1979, Volume: 88, Issue:3 Pt 1 Topics: Animals; Ethanolamines; Female; Intraocular Pressure; Isoproterenol; Labetalol; Norepinephrine; p-Hydroxyamphetamine; Phenoxybenzamine; Pupil; Rabbits; Sympathectomy; Timolol	1979
Comparative haemodynamic effects of labetalol, timolol, prazosin and the combination of tolamolol and prazosin. British journal of clinical pharmacology, 1979, Volume: 8, Issue:Suppl 2 Topics: Adult; Blood Pressure; Drug Combinations; Ethanolamines; Hemodynamics; Humans; Labetalol; Male; Middle Aged; Physical Exertion; Prazosin; Propanolamines; Quinazolines; Rest; Timolol	1979
Comparative effects of SCH 19927 and timolol on intraocular pressure of conscious rabbits and relative systemic beta-blockade resulting from topical administration. Journal of ocular pharmacology, 1985,Summer, Volume: 1, Issue:2 Topics: Animals; Labetalol; Ophthalmic Solutions; Rabbits; Receptors, Adrenergic, beta; Timolol	1985
Comparison of the effects of adrenergic agonists and alpha-, beta 1-, beta 2-antagonists on the intraocular pressure and adenylate cyclase activity in the ciliary processes of the rabbit. Acta ophthalmologica, 1985, Volume: 63, Issue:1 Topics: Acebutolol; Adenylyl Cyclases; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Ciliary Body; Intraocular Pressure; Isoproterenol; Labetalol; Metoprolol; Rats; Timolol; Water	1985
Endothelial potentiation of relaxation response to beta adrenoceptor blocking agents. The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:3 Topics: 5,8,11,14-Eicosatetraynoic Acid; Adrenergic beta-Antagonists; Animals; Aorta, Thoracic; Dinoprost; Dose-Response Relationship, Drug; Drug Synergism; Endothelium; Labetalol; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Propanolamines; Propranolol; Prostaglandin Endoperoxides, Synthetic; Prostaglandins F; Pyridines; Rats; Rats, Inbred Strains; Spiro Compounds; Timolol; Vasodilation	1986
Protection of CGS 10078B against ouabain-induced arrhythmia in the cat. Pharmacology, 1987, Volume: 35, Issue:1 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Blood Pressure; Cats; Dioxins; Female; Heart Rate; Hydroxydopamines; Labetalol; Male; Ouabain; Oxidopamine; Timolol	1987
Placental transfer of beta-adrenergic antagonists studied in an in vitro perfusion system of human placental tissue. American journal of obstetrics and gynecology, 1988, Volume: 159, Issue:1 Topics: Adrenergic beta-Antagonists; Atenolol; Celiprolol; Female; Humans; In Vitro Techniques; Labetalol; Maternal-Fetal Exchange; Placenta; Pregnancy; Propanolamines; Propranolol; Timolol	1988
The effect of ageing and disease on tear constituents. Transactions of the ophthalmological societies of the United Kingdom, 1985, Volume: 104 ( Pt 4) Topics: Adult; Aged; Aging; Blepharitis; Ceruloplasmin; Eyelid Diseases; Humans; Immunoglobulin A; Immunoglobulin G; Keratoconjunctivitis; Labetalol; Lactoferrin; Middle Aged; Muramidase; Pemphigoid, Bullous; Practolol; Propranolol; Tears; Timolol; Xerophthalmia	1985
Ocular hypotensive action of labetalol in rabbit and human eyes. Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology, 1981, Volume: 217, Issue:3 Topics: Animals; Dose-Response Relationship, Drug; Ethanolamines; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Labetalol; Male; Ophthalmic Solutions; Pilocarpine; Propranolol; Rabbits; Timolol	1981
Constitutively active mutants of the beta1-adrenergic receptor. FEBS letters, 1999, Sep-03, Volume: 457, Issue:3 Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Amino Acid Substitution; Betaxolol; Carbazoles; Carvedilol; Cell Line; Cyclic AMP; Epinephrine; Humans; Imidazoles; Isoproterenol; Labetalol; Point Mutation; Practolol; Propanolamines; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Recombinant Proteins; Timolol	1999
Modeling the electrophoretic mobility of beta-blockers in capillary electrophoresis using artificial neural networks. Farmaco (Societa chimica italiana : 1989), 2005, Volume: 60, Issue:3 Topics: Adrenergic beta-Antagonists; Atenolol; Electrolytes; Electrophoresis, Capillary; Electrophoretic Mobility Shift Assay; Labetalol; Models, Chemical; Neural Networks, Computer; Pharmaceutical Preparations; Practolol; Predictive Value of Tests; Propranolol; Solvents; Technology, Pharmaceutical; Timolol	2005