labetalol and sq-11725

labetalol has been researched along with sq-11725 in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19908 (22.86)18.7374
1990's2 (5.71)18.2507
2000's14 (40.00)29.6817
2010's9 (25.71)24.3611
2020's2 (5.71)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Baker, JG1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Akamatsu, M1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Bellman, K; Knegtel, RM; Settimo, L1
Fishbein, L; Jackson, CD1
Epstein, M; Oster, JR1
Kontić, D; Krieglstein, GK1
Charyev, KhE; Erina, EV1
Desiatnichenko, VM; Romakov, AIu; Sagirov, AM; Sobol', IuS; Sumarokov, AB1
Chung, DC; Laschuk, MJ1
Hopkins, GA1
Mancia, G1
Cho, CH; Yat, PC1
Cho, CH; Kaan, SK1
Akbay, C; Rizvi, SA; Shamsi, SA1
Jenkins, JK; Stamm, PL; Vigrass, HG1
Bragg, W; Norton, D; Shamsi, SA1
Jacobsen, SJ; Kalantar-Zadeh, K; Kovesdy, CP; Lee, MS; Neyer, JR; Shaw, SF; Shi, J; Sim, JJ; Zhou, H1
Ballotari, M; Gottardo, R; Tagliaro, F; Taus, F; Utzeri, C1

Reviews

4 review(s) available for labetalol and sq-11725

ArticleYear
A toxicological review of beta-adrenergic blockers.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1986, Volume: 6, Issue:3

    Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Atenolol; Cocarcinogenesis; Ethanolamines; Female; Kinetics; Labetalol; Lethal Dose 50; Male; Metoprolol; Mice; Mutagens; Nadolol; Neoplasms, Experimental; Oxprenolol; Pindolol; Practolol; Propanolamines; Propranolol; Rats; Sotalol; Timolol

1986
Beta blockers and renal function: a reappraisal.
    Journal of clinical hypertension, 1985, Volume: 1, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Blood Urea Nitrogen; Cardiac Output; Creatinine; Dogs; Glomerular Filtration Rate; Heart; Humans; Hypertension; Kidney; Labetalol; Metoprolol; Nadolol; Propanolamines; Propranolol; Renal Circulation; Renin; Sympathomimetics; Vascular Resistance

1985
The new beta-adrenergic antagonists.
    Canadian Anaesthetists' Society journal, 1984, Volume: 31, Issue:4

    Topics: Adrenergic beta-Antagonists; Atenolol; Humans; Labetalol; Metoprolol; Nadolol; Oxprenolol; Pindolol; Propanolamines; Timolol

1984
Drug treatment of glaucoma.
    American journal of optometry and physiological optics, 1984, Volume: 61, Issue:12

    Topics: Acetazolamide; Administration, Topical; Adrenergic beta-Antagonists; Bromocriptine; Clonidine; Dronabinol; Epinephrine; Glaucoma; Humans; Labetalol; Miotics; Nadolol; Parasympathomimetics; Pilocarpine; Propanolamines; Sympathomimetics; Timolol

1984

Trials

2 trial(s) available for labetalol and sq-11725

ArticleYear
Nadolol and labetalol: comparative efficacy of two beta-blocking agents in glaucoma.
    Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology, 1981, Volume: 216, Issue:4

    Topics: Adrenergic beta-Antagonists; Blood Pressure; Ethanolamines; Glaucoma; Heart Rate; Humans; Intraocular Pressure; Labetalol; Nadolol; Propanolamines

1981
[Comparative evaluation of the therapeutic effect of various classes of beta-blockaders in patients with hypertension].
    Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR, 1983, Volume: 6, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Clinical Trials as Topic; Echocardiography; Heart; Hemodynamics; Humans; Hypertension; Labetalol; Middle Aged; Nadolol; Propanolamines; Propranolol

1983

Other Studies

29 other study(ies) available for labetalol and sq-11725

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
The selectivity of beta-adrenoceptor antagonists at the human beta1, beta2 and beta3 adrenoceptors.
    British journal of pharmacology, 2005, Volume: 144, Issue:3

    Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Algorithms; Animals; Cell Line; CHO Cells; Cricetinae; Dioxoles; Humans; Propanolamines; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Receptors, Adrenergic, beta-3

2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
QSAR study on permeability of hydrophobic compounds with artificial membranes.
    Bioorganic & medicinal chemistry, 2007, Jun-01, Volume: 15, Issue:11

    Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Importance of physicochemical properties for the design of new pesticides.
    Journal of agricultural and food chemistry, 2011, Apr-13, Volume: 59, Issue:7

    Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic

2011
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
[Comparative study of the action of a series of new beta-adrenergic receptor blockaders in patients with effort angina].
    Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR, 1983, Volume: 6, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Angina Pectoris; Atenolol; Echocardiography; Exercise Test; Hemodynamics; Humans; Labetalol; Male; Middle Aged; Nadolol; Propanolamines; Propranolol

1983
Blood pressure variability at normal and high blood pressure.
    Chest, 1983, Volume: 83, Issue:2 Suppl

    Topics: Adolescent; Adult; Aged; Blood Pressure; Blood Pressure Determination; Clonidine; Heart Rate; Humans; Hypertension; Labetalol; Middle Aged; Monitoring, Physiologic; Nadolol; Propanolamines; Time Factors

1983
Effects of beta-adrenoceptor antagonists on portal vein hypertension and ethanol-induced gastric mucosal damage in rats.
    The Journal of pharmacy and pharmacology, 1994, Volume: 46, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Ethanol; Gastric Mucosa; Hemodynamics; Hypertension, Portal; Labetalol; Male; Metoprolol; Nadolol; Pindolol; Propranolol; Rats; Rats, Sprague-Dawley; Stomach Ulcer

1994
Study of propranolol and its related adrenoceptor antagonists on changes of gastric electrical parameters induced by ethanol in rats.
    Pharmacology, 1999, Volume: 58, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Butoxamine; Dose-Response Relationship, Drug; Electric Conductivity; Electrophysiology; Ethanol; Gastric Mucosa; Labetalol; Male; Metoprolol; Nadolol; Propranolol; Rats; Rats, Sprague-Dawley

1999
Polymeric alkenoxy amino acid surfactants: II. Chiral separations of beta-blockers with multiple stereogenic centers.
    Electrophoresis, 2004, Volume: 25, Issue:6

    Topics: Adrenergic beta-Antagonists; Alkenes; Chromatography, Micellar Electrokinetic Capillary; Cyclodextrins; Electrolytes; Isoleucine; Labetalol; Leucine; Micelles; Molecular Structure; Nadolol; Polymers; Stereoisomerism; Surface-Active Agents; Temperature

2004
Suspected beta-antagonist-induced thrombocytopenia.
    The Annals of pharmacotherapy, 2005, Volume: 39, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Female; Humans; Labetalol; Lupus Erythematosus, Systemic; Nadolol; Splenectomy; Thrombocytopenia

2005
Optimized separation of beta-blockers with multiple chiral centers using capillary electrochromatography-mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2008, Nov-01, Volume: 875, Issue:1

    Topics: Adrenergic beta-Antagonists; Capillary Electrochromatography; Labetalol; Multivariate Analysis; Nadolol; Solvents; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Temperature

2008
β-Blocker Use and Risk of Mortality in Heart Failure Patients Initiating Maintenance Dialysis.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2021, Volume: 77, Issue:5

    Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Atenolol; Bisoprolol; Carvedilol; Cause of Death; Cohort Studies; Female; Heart Failure; Hospitalization; Humans; Kidney Failure, Chronic; Labetalol; Logistic Models; Male; Metoprolol; Middle Aged; Mortality; Nadolol; Proportional Hazards Models; Propranolol; Protective Factors; Renal Dialysis; Retrospective Studies; Risk; Risk Factors

2021
Hair analysis for beta-blockers and calcium-channel blockers by using liquid chromatography-tandem mass spectrometry as a tool for monitoring adherence to antihypertensive therapy.
    Drug testing and analysis, 2022, Volume: 14, Issue:10

    Topics: Adrenergic beta-Antagonists; Amlodipine; Antihypertensive Agents; Atenolol; Bisoprolol; Calcium; Calcium Channel Blockers; Chromatography, Liquid; Hair Analysis; Humans; Labetalol; Metoprolol; Nadolol; Nebivolol; Reproducibility of Results; Sotalol; Tandem Mass Spectrometry

2022