labetalol has been researched along with sq-11725 in 35 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 8 (22.86) | 18.7374 |
1990's | 2 (5.71) | 18.2507 |
2000's | 14 (40.00) | 29.6817 |
2010's | 9 (25.71) | 24.3611 |
2020's | 2 (5.71) | 2.80 |
Authors | Studies |
---|---|
Topliss, JG; Yoshida, F | 1 |
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P | 1 |
Baker, JG | 1 |
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R | 1 |
Lombardo, F; Obach, RS; Waters, NJ | 1 |
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Campillo, NE; Guerra, A; Páez, JA | 1 |
García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
Ekins, S; Williams, AJ; Xu, JJ | 1 |
Akamatsu, M | 1 |
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
Bellman, K; Knegtel, RM; Settimo, L | 1 |
Fishbein, L; Jackson, CD | 1 |
Epstein, M; Oster, JR | 1 |
Kontić, D; Krieglstein, GK | 1 |
Charyev, KhE; Erina, EV | 1 |
Desiatnichenko, VM; Romakov, AIu; Sagirov, AM; Sobol', IuS; Sumarokov, AB | 1 |
Chung, DC; Laschuk, MJ | 1 |
Hopkins, GA | 1 |
Mancia, G | 1 |
Cho, CH; Yat, PC | 1 |
Cho, CH; Kaan, SK | 1 |
Akbay, C; Rizvi, SA; Shamsi, SA | 1 |
Jenkins, JK; Stamm, PL; Vigrass, HG | 1 |
Bragg, W; Norton, D; Shamsi, SA | 1 |
Jacobsen, SJ; Kalantar-Zadeh, K; Kovesdy, CP; Lee, MS; Neyer, JR; Shaw, SF; Shi, J; Sim, JJ; Zhou, H | 1 |
Ballotari, M; Gottardo, R; Tagliaro, F; Taus, F; Utzeri, C | 1 |
4 review(s) available for labetalol and sq-11725
Article | Year |
---|---|
A toxicological review of beta-adrenergic blockers.
Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Atenolol; Cocarcinogenesis; Ethanolamines; Female; Kinetics; Labetalol; Lethal Dose 50; Male; Metoprolol; Mice; Mutagens; Nadolol; Neoplasms, Experimental; Oxprenolol; Pindolol; Practolol; Propanolamines; Propranolol; Rats; Sotalol; Timolol | 1986 |
Beta blockers and renal function: a reappraisal.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Blood Urea Nitrogen; Cardiac Output; Creatinine; Dogs; Glomerular Filtration Rate; Heart; Humans; Hypertension; Kidney; Labetalol; Metoprolol; Nadolol; Propanolamines; Propranolol; Renal Circulation; Renin; Sympathomimetics; Vascular Resistance | 1985 |
The new beta-adrenergic antagonists.
Topics: Adrenergic beta-Antagonists; Atenolol; Humans; Labetalol; Metoprolol; Nadolol; Oxprenolol; Pindolol; Propanolamines; Timolol | 1984 |
Drug treatment of glaucoma.
Topics: Acetazolamide; Administration, Topical; Adrenergic beta-Antagonists; Bromocriptine; Clonidine; Dronabinol; Epinephrine; Glaucoma; Humans; Labetalol; Miotics; Nadolol; Parasympathomimetics; Pilocarpine; Propanolamines; Sympathomimetics; Timolol | 1984 |
2 trial(s) available for labetalol and sq-11725
Article | Year |
---|---|
Nadolol and labetalol: comparative efficacy of two beta-blocking agents in glaucoma.
Topics: Adrenergic beta-Antagonists; Blood Pressure; Ethanolamines; Glaucoma; Heart Rate; Humans; Intraocular Pressure; Labetalol; Nadolol; Propanolamines | 1981 |
[Comparative evaluation of the therapeutic effect of various classes of beta-blockaders in patients with hypertension].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Clinical Trials as Topic; Echocardiography; Heart; Hemodynamics; Humans; Hypertension; Labetalol; Middle Aged; Nadolol; Propanolamines; Propranolol | 1983 |
29 other study(ies) available for labetalol and sq-11725
Article | Year |
---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties | 2004 |
The selectivity of beta-adrenoceptor antagonists at the human beta1, beta2 and beta3 adrenoceptors.
Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Algorithms; Animals; Cell Line; CHO Cells; Cricetinae; Dioxoles; Humans; Propanolamines; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Receptors, Adrenergic, beta-3 | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
QSAR study on permeability of hydrophobic compounds with artificial membranes.
Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Importance of physicochemical properties for the design of new pesticides.
Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic | 2011 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
[Comparative study of the action of a series of new beta-adrenergic receptor blockaders in patients with effort angina].
Topics: Adrenergic beta-Antagonists; Adult; Angina Pectoris; Atenolol; Echocardiography; Exercise Test; Hemodynamics; Humans; Labetalol; Male; Middle Aged; Nadolol; Propanolamines; Propranolol | 1983 |
Blood pressure variability at normal and high blood pressure.
Topics: Adolescent; Adult; Aged; Blood Pressure; Blood Pressure Determination; Clonidine; Heart Rate; Humans; Hypertension; Labetalol; Middle Aged; Monitoring, Physiologic; Nadolol; Propanolamines; Time Factors | 1983 |
Effects of beta-adrenoceptor antagonists on portal vein hypertension and ethanol-induced gastric mucosal damage in rats.
Topics: Adrenergic beta-Antagonists; Animals; Ethanol; Gastric Mucosa; Hemodynamics; Hypertension, Portal; Labetalol; Male; Metoprolol; Nadolol; Pindolol; Propranolol; Rats; Rats, Sprague-Dawley; Stomach Ulcer | 1994 |
Study of propranolol and its related adrenoceptor antagonists on changes of gastric electrical parameters induced by ethanol in rats.
Topics: Adrenergic beta-Antagonists; Animals; Butoxamine; Dose-Response Relationship, Drug; Electric Conductivity; Electrophysiology; Ethanol; Gastric Mucosa; Labetalol; Male; Metoprolol; Nadolol; Propranolol; Rats; Rats, Sprague-Dawley | 1999 |
Polymeric alkenoxy amino acid surfactants: II. Chiral separations of beta-blockers with multiple stereogenic centers.
Topics: Adrenergic beta-Antagonists; Alkenes; Chromatography, Micellar Electrokinetic Capillary; Cyclodextrins; Electrolytes; Isoleucine; Labetalol; Leucine; Micelles; Molecular Structure; Nadolol; Polymers; Stereoisomerism; Surface-Active Agents; Temperature | 2004 |
Suspected beta-antagonist-induced thrombocytopenia.
Topics: Adrenergic beta-Antagonists; Adult; Female; Humans; Labetalol; Lupus Erythematosus, Systemic; Nadolol; Splenectomy; Thrombocytopenia | 2005 |
Optimized separation of beta-blockers with multiple chiral centers using capillary electrochromatography-mass spectrometry.
Topics: Adrenergic beta-Antagonists; Capillary Electrochromatography; Labetalol; Multivariate Analysis; Nadolol; Solvents; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Temperature | 2008 |
β-Blocker Use and Risk of Mortality in Heart Failure Patients Initiating Maintenance Dialysis.
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Atenolol; Bisoprolol; Carvedilol; Cause of Death; Cohort Studies; Female; Heart Failure; Hospitalization; Humans; Kidney Failure, Chronic; Labetalol; Logistic Models; Male; Metoprolol; Middle Aged; Mortality; Nadolol; Proportional Hazards Models; Propranolol; Protective Factors; Renal Dialysis; Retrospective Studies; Risk; Risk Factors | 2021 |
Hair analysis for beta-blockers and calcium-channel blockers by using liquid chromatography-tandem mass spectrometry as a tool for monitoring adherence to antihypertensive therapy.
Topics: Adrenergic beta-Antagonists; Amlodipine; Antihypertensive Agents; Atenolol; Bisoprolol; Calcium; Calcium Channel Blockers; Chromatography, Liquid; Hair Analysis; Humans; Labetalol; Metoprolol; Nadolol; Nebivolol; Reproducibility of Results; Sotalol; Tandem Mass Spectrometry | 2022 |