labetalol and propranolol

labetalol has been researched along with propranolol in 217 studies

Research

Studies (217)

TimeframeStudies, this research(%)All Research%
pre-1990131 (60.37)18.7374
1990's27 (12.44)18.2507
2000's22 (10.14)29.6817
2010's33 (15.21)24.3611
2020's4 (1.84)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Topliss, JG; Yoshida, F1
Faller, B; Wohnsland, F1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Baker, JG1
Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R1
Artursson, P; Bergström, CA; Draheim, R; Holmén, AG; Wassvik, CM1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Campillo, NE; Guerra, A; Páez, JA1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Glen, RC; Lowe, R; Mitchell, JB1
Ekins, S; Williams, AJ; Xu, JJ1
Akamatsu, M1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Crawford, DH; Fletcher, LM; Li, P; Roberts, MS; Robertson, TA; Thorling, CA; Zhang, Q1
Chavatte, P; Dubois, J; Farce, A; Furman, C; Gilleron, P; Hénichart, JP; Le Broc-Ryckewaert, D; Lemoine, A; Millet, R; Pommery, N; Wlodarczyk, N1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Buckley, DB; Funk, RS; Hensley, T; Kazmi, F; Loewen, GJ; Parkinson, A; Pope, C1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Alam, MA; Drewes, LR; Gurrapu, S; Jonnalagadda, SK; Lueth, EA; Mereddy, VR; Nelson, GL; Ronayne, CT; Solano, LN1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Abouf, M; Abutaleb, NS; Chen, L; Elsebaei, MM; Ghiaty, A; Hegazy, YA; Malwal, SR; Mayhoub, AS; Mohammad, H; Oldfield, E; Seleem, MN; Zhang, J1
Chang, Q; Chen, Z; Hu, G; Hu, L; Li, Q; Long, J1
Brittain, RT; Levy, GP1
Brown, JJ; Fraser, R; Lever, AF; Morton, JJ; Robertson, JI; Rosei, EA; Trust, PM4
Wilcox, RG1
Dobbs, RJ; Prichard, BN; Richards, DA1
Hobson, JD; Jauernig, RA; Moulds, RF; Shaw, J1
Hashimoto, K; Hashimoto, T; Iizuka, H; Imai, S; Matsuda, H; Tsukada, T1
Sommers, DK3
Carey, B; Whalley, ET1
Nencini, P1
Gaddie, J; Palmer, KN; Skinner, C1
Kennedy, I; Levy, GP1
Armstrong, BK; Beilin, L; Nassim, M; Pugsley, DJ1
Cooper, R; Gear, JS; Ledingham, JG; Steiner, JA1
Allonen, H; Kleimola, T; Lehtonen, A1
Nyberg, G; Vedin, A; Wilhelmsson, C1
Anstad, U; Lote, K; Nordøy, A; Svenson, B1
Armstrong, BK; Beilin, LJ; Nassim, MA; Pugsley, DJ1
Boakes, AJ; Joekes, AM; Prichard, BN; Thompson, FO1
Maconochie, JG; Richards, DA; Woodings, EP3
Armstrong, B; Beilin, LJ; Nassim, M; Pugsley, D1
Blankesteijn, WM; Graafsma, SJ; Hectors, MP; Olde Riekerink, EA; Rodrigues de Miranda, JF; Thien, T1
Goldberg, SR; Schindler, CW; Tella, SR1
Demopoulos, CA; Kapoulas, VM; Tsangaris, GT; Tsoukatos, DC1
Cattaneo, BM; Giannattasio, C; Grassi, G; Mancia, G; Perondi, R; Seravalle, G; Zanchetti, A1
Boer, GJ; Botterblom, MH; De Barrios, J; Erdtsieck-Ernste, EB; Feenstra, MG1
Mills, RG; Roberts, MS; Shen, JJ; Wanwimolruk, S1
Latini, R; Mennini, T; Riva, E1
Kato, T; Kinjo, N; Moromizato, H; Noguchi, K; Sakanashi, M1
Hara, Y; Maniwa, T; Miyagishi, A; Noguchi, T1
Bilić, A; Ljubicić, N1
Nakajima, M; Ueda, M1
Richardson, SB; Twente, S1
Davidson, JM; Maurice, J; Richardson, R; Smith, ER; Walter, T1
Hall, WD; Hirsch, A; Massie, B; Porter, V; Szlachcic, J; Tubau, JF; Vollmer, C; Wollam, G1
Davies, G; Hyer, SL; Kohner, EM; Mackay, EM; VandenBurg, MJ1
Døssing, M; Hamberg, O; Loft, S; Olesen, KL; Sonne, J; Thyssen, H; Victor, MA; Vollmer-Larsen, A1
Babov, KD; Il'iash, MG; Kravtsova, LA; Shcherbak, IaIu1
Louis, WJ; Rand, MJ; Story, DF; Tung, LH1
Antonellis, A; Pula, K; Rivelli, M; Sybertz, EJ; Watkins, RW2
Cronin, CJ; Graham, BR; Prichard, BN; Tomlinson, B1
Dangman, KH; Zaim, S1
Bertora, PL; Bevilacqua, M; Bosisio, E; Chebat, E; Norbiato, G; Sardina, M; Savonitto, S1
Cleroux, J; Giannattasio, C; Grassi, G; Mancia, G; Seravalle, G; Zanchetti, A1
Bedsole, GD; Cubbon, J; Davidov, ME; Frishman, WH; Gorwit, J; Michelson, EL; Poland, MP; Schoenberger, JA; Wallin, JD1
Charlap, S; Frishman, WH; Shapiro, W1
Davidov, ME; Frishman, WH; Gorwit, JI; Michelson, EL; Poland, MP; Schoenberger, JA; Wallin, JD1
Davies, G; Hyer, SL; Kohner, EM; Mackay, EM; Vanden Burg, MJ1
Atwood, J; Walsh, M1
Aisa, L; Pelegrí, A; Reguant, M; Romero, R1
Carr, ME; Cubeddu, LX; Fuenmayor, NJ1
Rietbrock, N; Woodcock, BG1
Harron, DW; Riddell, JG; Shanks, RG1
Honda, K; Miyata-Osawa, A; Nakagawa, C; Shiono, K; Takenaka, T1
Calder, AA; Forbes, CD; Greer, IA; McLaren, M; Walker, JJ2
Lepäntalo, M2
Matsunaga, K; Nakamura, K; Ueda, M1
Fishbein, L; Jackson, CD1
Smirnov, GB1
Epstein, M; Oster, JR1
Kanno, M; Nakaya, H; Tohse, N1
Maddox, YT; Mostaghim, R; Ramwell, PW1
Kreutner, W; Rizzo, C1
Bernini, F; Cighetti, G; Corsini, A; Fumagalli, R; Galli, G; Soma, M1
Clerici, C; Harf, A; Macquin-Mavier, I1
Pandhi, P; Sharma, PL1
Fujimoto, T; Fujita, E; Hazu, R; Iwasaki, Y; Nagasaka, Y; Nakajima, S; Tanaka, A; Touda, Y; Tsuya, Y; Uenishi, H1
Proegler, M; Schneider, H1
Viinikka, L; Ylikorkala, O1
Sharaeva, ML; Zaĭtseva, VI1
Bompart, F; Graham, BR; Liu, JB; Prichard, BN; Tomlinson, B1
Hashimoto, T; Kaguchi, Y; Kimura, M; Kuriyama, S; Miyahara, T; Nakamura, K; Tamai, K; Tamura, H1
Ivanova, DK; Mironova, OV; Shkliar, LV; Sirenko, IuN1
Colditz, GA; Delea, TE; Huse, DM; Oster, G; Savage, DD1
Ayuso Gatell, A; Martínez Ferrer, JR; Pujol Colomer, J; Trenchs Verdaguer, X1
Curry, C; Hinds, J; Kong, BW; Medakovic, M; Poland, M; Roper, K; Saunders, E1
Armario, A; Garvey, JS; Hidalgo, J1
Mrakovcić, I; Pahor, D; Polić, L; Radosević-Stasić, B; Rukavina, D1
Glogar, DH1
Pandhi, P; Sharma, BK; Sharma, PL; Wahi, PL1
Matsumura, Y; Morimoto, S1
Kameda, H1
Banim, SO; Butrous, GS; Camm, AJ; Maltz, MB; O'Keefe, J1
Lepäntalo, M; Lindström, BL; Tötterman, KJ1
Berry, DA; Finley, D; Holtzman, JL; Johnson, B; Sirgo, MA1
Due, DL; Giguere, GC; Plachetka, JR1
Seal, DV1
Aslam, S; Pandhi, P; Sharma, BK; Sharma, PL; Wahi, PL1
Flamenbaum, W1
Burford, JG; Chetty, K; Conrad, SA; George, RB; Hudson, LD; Light, RW; Manocha, K1
Carr, AA; Flamenbaum, W; Materson, BJ; McMahon, FG; Poland, M; Weber, MA1
Calder, AA; Forbes, CD; Greer, IA; Walker, JJ1
ten Berge, BS; van der Veur, E; Wesseling, H; Wouda, AA1
Burris, JF1
Giorgetti, F; Re, L; Rossini, L1
Re, L; Rossini, L1
Larsson, K1
Clifton, JE; Collins, I; Hallett, P; Hartley, D; Lunts, LH; Wicks, PD1
Carlsen, JE; Christensen, NJ; Hartling, OJ; Svendsen, TL; Tangø, M; Trap-Jensen, J1
Adam, WR; Barter, CE; Meagher, EJ1
Charyev, KhE; Erina, EV1
Desiatnichenko, VM; Romakov, AIu; Sagirov, AM; Sobol', IuS; Sumarokov, AB1
Bengtsson, C1
Coote, JH; Kubik, MM1
Johns, VJ1
Cherenshchikova, EA; Filippov, AK; Iuzhakov, SD; Mashkovskiĭ, MD; Porotikov, VI1
Bamonte, F; Forlani, A; Monopoli, A; Ongini, E; Parravicini, L1
Abiko, Y; Hosaka, A; Kogure, H1
Ahuja, RC; Nelson, GI; Silke, B; Taylor, SH2
Anand, MP; Dattani, KK; Doshi, BS; Kulkarni, RD2
Anand, MP; Datey, KK; Dattani, KK1
Ahuja, RC; Nelson, GI; Silke, B; Taylor, SH; Walker, C1
Borthwick, JM; Jones, RM; Lovelock, HA; Pollard, BJ; Rowbottom, SJ1
Doyle, AE1
Clanachan, AS; Forbes, R; Moonie, GT1
Ahuja, RC; Nelson, GI; Okoli, RC; Silke, B; Taylor, SH1
Krug, H; Ochotny, R; Poprawski, K1
Bellucci, R; Bonomi, L; Massa, F; Noya, E; Perfetti, S1
Bauer, GE; Hunyor, SN; Larkin, H; Ross, M1
Bjurö, T; Hagman, M; Nyberg, G; Smith, U1
Berg, KJ; Nilsen, OG; Walstad, RA; Wessel-Aas, T1
Berglund, G; Nyberg, G1
Bulpitt, CJ; Butler, AG; Husaini, MH; Nicholls, DP; Stephens, MD1
Chalmers, JP; Graham, JR; Grygiel, JJ; Mulligan, J; Walkley, J; West, MJ; Wing, LM1
Donker, AJ; May, JF; ten Berge, BS; van der Veur, E; Wesseling, H1
Ambrosioni, E; Magnani, B; Malini, PL; Negroni, S; Strocchi, E1
Daneshmend, TK; Roberts, CJ1
Gomez, G1
Agabiti-Rosei, E; Alicandri, CL; Beschi, M; Boni, E; Castellano, M; Fariello, R; Montini, E; Muiesan, G; Romanelli, G; Zaninelli, A1
Agabiti-Rosei, E; Alicandri, C; Beschi, M; Boni, E; Castellano, M; Fariello, R; Muiesan, G; Muiesan, ML; Romanelli, G1
Kogure, H1
Colombo, G; Fea, F; Foti, F; Pelliccioli, I; Planca, E; Salvioli, G1
Berg, KJ; Walstad, RA; Wessel-Aas, T1
Riley, AJ; Riley, EJ1
Larsen, JS; Pedersen, EB2
Harvald, B1
Chew, SL; Grossman, AB; Sheaves, R1
Cho, CH; Yat, PC1
Annane, D; Bellissant, E; Giudicelli, JF; Thuillez, C1
Janssen, BJ; Oosting, J; Struyker-Boudier, HA; Tyssen, CM1
Arner, P; Galitzky, J; Lafontan, M; Nordenström, J1
Botterblom, MH; Erdtsieck-Ernste, EB; Feenstra, MG1
Kemp, GJ; Odoom, JE; Radda, GK1
Kilár, F1
Carrupt, PA; Cheymol, G; Levron, JC; Poirier, JM; Snoeck, E; Testa, B; Weissenburger, J1
Cho, CH; Kaan, SK1
Brocher, N; Copeland, A; Godfrey, J; Thornton, H; Wilson, C1
Lind, L; Millgård, J; von zur Můhlen, B1
Chen, IJ; Chiang, LC; Chiu, CC; Liang, JC; Lin, YT; Tsai, CH; Wu, JR; Yeh, JL1
Enlow, B; Howell, JM; Klein-Schwartz, W; Litovitz, TL; Love, JN1
Dupont, S; Mallefet, J; Vanderlinden, C1
Accinni, R; Bonacina, E; Brenna, S; Pinelli, A; Tomasoni, L; Trivulzio, S1
Asadpour-Zeynali, K; Jouyban, A; Majidi, MR1
Campisi, J; Fleshner, M; Greenwood, BN; Johnson, JD; Kennedy, SL; Nickerson, M; Sharkey, CM1
Arima, Y; Hasegawa, C; Izawa, H; Kumazawa, T; Lee, XP; Sato, K; Umezawa, H1
Ikonen, M; Kontturi, K; Murtomäki, L1
Bao, J; Johnson, PE; Krylov, SN; Krylova, SM; Reinstein, O; Wilson, DJ1
Crawford, DH; Fletcher, LM; Li, P; Roberts, MS; Robertson, TA; Weiss, M; Zhang, Q1
Tohda, Y1
Harken, AH1
Bagcivan, I; Berkan, O; Göksel, S; Korkmaz, O; Saraç, B; Yildirim, S1
Alawi, KM; Aubdool, AA; Brain, SD; Keeble, JE; Liang, L; Psefteli, MP; Vepa, A; Wilde, E1
Chen, W; Duan, L; Lee, MS; Ng, A; Nguyen, J; Shen, AY; Spencer, HT1
Madias, JE1
Tornvall, P; Y-Hassan, S1
Badaoui, M; Dickson, CJ; Hornak, V; Kells, A; Molteni, C; Rosta, E1
Chen, W; Duan, L; Lee, MS; Ng, A; Spencer, HT1
Dingle, LMK; Edkins, AL; Veale, CGL; Weyers, C; Wilhelmi, BS1
Aboul-Enein, HY; Ali, I; ALOthman, ZA; Alsheetan, KM1
Jacobsen, SJ; Kalantar-Zadeh, K; Kovesdy, CP; Lee, MS; Neyer, JR; Shaw, SF; Shi, J; Sim, JJ; Zhou, H1

Reviews

9 review(s) available for labetalol and propranolol

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
A review of the animal pharmacology of labetalol, a combined alpha- and beta-adrenoceptor-blocking drug.
    British journal of clinical pharmacology, 1976, Volume: 3, Issue:4 Suppl 3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Autonomic Fibers, Preganglionic; Desoxycorticosterone; Dogs; Electric Stimulation; Ethanolamines; Guinea Pigs; Hemodynamics; Hypertension; Hypertension, Renal; In Vitro Techniques; Isoproterenol; Labetalol; Male; Muscle Contraction; Muscle, Smooth; Myocardial Contraction; Phentolamine; Phenylephrine; Propranolol; Rabbits; Rats

1976
A toxicological review of beta-adrenergic blockers.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1986, Volume: 6, Issue:3

    Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Atenolol; Cocarcinogenesis; Ethanolamines; Female; Kinetics; Labetalol; Lethal Dose 50; Male; Metoprolol; Mice; Mutagens; Nadolol; Neoplasms, Experimental; Oxprenolol; Pindolol; Practolol; Propanolamines; Propranolol; Rats; Sotalol; Timolol

1986
Beta blockers and renal function: a reappraisal.
    Journal of clinical hypertension, 1985, Volume: 1, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Blood Urea Nitrogen; Cardiac Output; Creatinine; Dogs; Glomerular Filtration Rate; Heart; Humans; Hypertension; Kidney; Labetalol; Metoprolol; Nadolol; Propanolamines; Propranolol; Renal Circulation; Renin; Sympathomimetics; Vascular Resistance

1985
Cost effectiveness of labetalol and propranolol in the treatment of hypertension among blacks.
    Journal of the National Medical Association, 1987, Volume: 79, Issue:10

    Topics: Aged; Black People; Clinical Trials as Topic; Cost-Benefit Analysis; Female; Humans; Hypertension; Labetalol; Male; Middle Aged; Propranolol

1987
Beta-blocking drugs for arrhythmias, hypertension, and ischemic heart disease.
    American journal of surgery, 1984, Volume: 147, Issue:6

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Animals; Arrhythmias, Cardiac; Atenolol; Blood Pressure; Coronary Disease; Dogs; Heart Rate; Humans; Hypertension; Labetalol; Myocardial Infarction; Propranolol

1984
Hypertension and calcium antagonists.
    Clinical and experimental pharmacology & physiology. Supplement, 1982, Volume: 6

    Topics: Airway Resistance; Antihypertensive Agents; Calcium Channel Blockers; Humans; Hypertension; Labetalol; Pindolol; Propranolol; Verapamil

1982
[My research on asthma today and in the future].
    Arerugi = [Allergy], 2013, Volume: 62, Issue:11

    Topics: Adrenergic beta-Antagonists; Animals; Anti-Inflammatory Agents; Asthma; Bronchial Hyperreactivity; Disease Models, Animal; Humans; Interleukin-4; Labetalol; Lymphocytes; Phosphoric Diester Hydrolases; Propranolol; Receptors, GABA; Receptors, Muscarinic; Theophylline; Thiadiazoles

2013

Trials

63 trial(s) available for labetalol and propranolol

ArticleYear
Randomised study of six beta-blockers and a thiazide diuretic in essential hypertension.
    British medical journal, 1978, Aug-05, Volume: 2, Issue:6134

    Topics: Acebutolol; Adrenergic beta-Antagonists; Adult; Atenolol; Bendroflumethiazide; Clinical Trials as Topic; Female; Humans; Hypertension; Labetalol; Male; Middle Aged; Pindolol; Propranolol; Random Allocation; Timolol

1978
Comparison of intravenous AH 5158 (ibidomide) and propranolol in asthma.
    British medical journal, 1975, Apr-12, Volume: 2, Issue:5962

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Asthma; Bronchi; Clinical Trials as Topic; Constriction; Ethanolamines; Female; Heart Rate; Humans; Injections, Intravenous; Labetalol; Male; Middle Aged; Placebos; Propranolol; Pulse; Respiration; Spirometry

1975
A controlled trial of labetalol (Trandate), propranolol and placebo in the management of mild to moderate hypertension.
    British journal of clinical pharmacology, 1979, Volume: 7, Issue:1

    Topics: Adult; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Ethanolamines; Female; Heart Rate; Humans; Hypertension; Labetalol; Male; Middle Aged; Placebos; Propranolol; Time Factors

1979
Vascular symptoms in patients with primary Raynaud's phenomenon are not exacerbated by propranolol or labetalol.
    British journal of clinical pharmacology, 1979, Volume: 7, Issue:4

    Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Ethanolamines; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Labetalol; Male; Middle Aged; Propranolol; Raynaud Disease; Skin Temperature

1979
Antihypertensive effect and plasma levels of labetalol. A comparison with propranolol and dihydrallazine.
    International journal of clinical pharmacology and biopharmacy, 1979, Volume: 17, Issue:2

    Topics: Adult; Dihydralazine; Drug Therapy, Combination; Ethanolamines; Female; Heart Rate; Humans; Hydralazine; Hypertension; Labetalol; Male; Middle Aged; Placebos; Propranolol; Time Factors

1979
Effects of labetalol and propranolol on blood pressure at rest and during isometric and dynamic exercise.
    European journal of clinical pharmacology, 1979, Volume: 16, Issue:5

    Topics: Adult; Blood Pressure; Ethanolamines; Fatigue; Heart Rate; Humans; Isometric Contraction; Labetalol; Male; Physical Exertion; Propranolol; Rest

1979
The effects of a combined alpha- and beta-blocking drug, labetalol, on some aspects of platelet function.
    Thrombosis and haemostasis, 1978, Oct-31, Volume: 40, Issue:2

    Topics: Adult; Blood Platelets; Blood Pressure; Ethanolamines; Female; Humans; Labetalol; Male; Middle Aged; Platelet Aggregation; Platelet Factor 3; Propranolol

1978
Controlled comparison of labetalol and propranolol in the management of severe hypertension.
    British journal of clinical pharmacology, 1976, Volume: 3, Issue:4 Suppl 3

    Topics: Adult; Antibodies, Antinuclear; Aspartate Aminotransferases; Blood Pressure; Clinical Trials as Topic; Diuretics; Dose-Response Relationship, Drug; Drug Evaluation; Drug Therapy, Combination; Ethanolamines; Female; Humans; Hypertension; Labetalol; Male; Middle Aged; Propranolol; Pulse; Time Factors

1976
Effect of blood pressure angiotensin II and aldosterone concentrations during treatment of severe hypertension with intravenous labetalol: comparison with propranolol.
    British journal of clinical pharmacology, 1976, Volume: 3, Issue:4 Suppl 3

    Topics: Aldosterone; Angiotensin II; Blood Pressure; Clinical Trials as Topic; Ethanolamines; Heart Rate; Humans; Hypertension; Injections, Intravenous; Labetalol; Propranolol

1976
Some haemodynamic effects of compound AH 5158 compared with propranolol, propranolol plus hydrallazine, and diazoxide: the use of AH 5158 in the treatment of hypertension.
    Clinical science and molecular medicine. Supplement, 1975, Volume: 2

    Topics: Blood Pressure; Cardiac Output; Clinical Trials as Topic; Diazoxide; Drug Therapy, Combination; Ethanolamines; Heart Rate; Humans; Hydralazine; Hypertension; Labetalol; Physical Exertion; Posture; Propranolol

1975
Comparison of the effects of labetalol and propranolol in healthy men at rest and during exercise.
    British journal of clinical pharmacology, 1977, Volume: 4, Issue:1

    Topics: Adult; Blood Pressure; Ethanolamines; Heart Rate; Humans; Labetalol; Male; Peak Expiratory Flow Rate; Physical Exertion; Propranolol; Time Factors

1977
Effects of labetalol and propranolol on histamine-induced bronchoconstriction in normal subjects.
    British journal of clinical pharmacology, 1977, Volume: 4, Issue:2

    Topics: Adult; Blood Pressure; Bronchi; Drug Interactions; Ethanolamines; Forced Expiratory Volume; Histamine; Humans; Labetalol; Male; Propranolol; Pulse

1977
Modification of pressor responses induced by 'cold' [proceedings].
    British journal of clinical pharmacology, 1977, Volume: 4, Issue:3

    Topics: Adult; Blood Pressure; Cardiac Output; Cold Temperature; Heart Rate; Humans; Labetalol; Male; Phentolamine; Propranolol

1977
Effects of intravenous labetalol on blood pressure, angiotensin II and aldosterone in hypertension: comparison with propranolol.
    Clinical science and molecular medicine. Supplement, 1976, Volume: 3

    Topics: Aldosterone; Angiotensin II; Depression, Chemical; Ethanolamines; Heart Rate; Humans; Hypertension; Labetalol; Propranolol

1976
Combined alpha- and beta-adrenoreceptor blockade in hypertension: a controlled trial of labetalol (AH 5158) compared with propranolol and placebo.
    Clinical science and molecular medicine. Supplement, 1976, Volume: 3

    Topics: Adult; Aged; Ethanolamines; Female; Humans; Hypertension; Labetalol; Male; Middle Aged; Physical Exertion; Posture; Propranolol; Pulse

1976
Does treatment with beta-adrenergic blocking agents cause a decrease in beta 2-adrenoceptor affinity?
    European journal of clinical pharmacology, 1992, Volume: 42, Issue:6

    Topics: Adrenergic beta-Antagonists; Adult; Albuterol; Blood Pressure; Double-Blind Method; Heart Rate; Humans; Labetalol; Leukocytes, Mononuclear; Male; Pindolol; Propranolol; Radioligand Assay; Receptors, Adrenergic, beta

1992
The effects of selective and non-selective adrenoceptor blockade on the portal blood flow in patients with liver cirrhosis.
    Scandinavian journal of gastroenterology, 1991, Volume: 26, Issue:7

    Topics: Adult; Analysis of Variance; Atenolol; Blood Flow Velocity; Female; Humans; Labetalol; Liver Cirrhosis; Male; Middle Aged; Portal System; Propranolol; Sympatholytics; Ultrasonography

1991
Left ventricular hypertrophy reversal with labetalol and propranolol: a prospective randomized, double-blind study.
    Cardiovascular drugs and therapy, 1990, Volume: 4, Issue:2

    Topics: Adult; Blood Pressure; Cardiomegaly; Double-Blind Method; Echocardiography; Female; Heart Rate; Humans; Labetalol; Male; Middle Aged; Propranolol; Prospective Studies; Time Factors; Ventricular Function, Left

1990
Effects of dilevalol, propranolol and placebo on retinal blood flow, blood pressure and heart rate: a double-blind study.
    Journal of human hypertension, 1990, Volume: 4 Suppl 2

    Topics: Blood Flow Velocity; Blood Pressure; Double-Blind Method; Heart Rate; Humans; Labetalol; Propranolol; Randomized Controlled Trials as Topic; Reference Values; Retinal Vessels

1990
Single dose pharmacokinetics and pharmacodynamics of oral oxazepam during concomitant administration of propranolol and labetalol.
    British journal of clinical pharmacology, 1990, Volume: 29, Issue:1

    Topics: Adult; Drug Interactions; Female; Humans; Labetalol; Male; Oxazepam; Propranolol; Psychomotor Performance; Reaction Time

1990
Haemodynamics of carvedilol in normal subjects compared with propranolol, pindolol, and labetalol.
    Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 11

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Blood Pressure; Carbazoles; Carvedilol; Dose-Response Relationship, Drug; Double-Blind Method; Heart Rate; Hemodynamics; Humans; Labetalol; Male; Physical Exertion; Pindolol; Propanolamines; Propranolol; Random Allocation

1987
Role of the Frank-Starling mechanism in maintaining cardiac output during increasing levels of treadmill exercise in beta-blocked normal men.
    The American journal of cardiology, 1989, Apr-01, Volume: 63, Issue:12

    Topics: Adrenergic beta-Antagonists; Adult; Cardiac Output; Heart; Heart Rate; Humans; Labetalol; Male; Oxygen Consumption; Physical Exertion; Propranolol; Pulmonary Gas Exchange; Respiration; Stroke Volume

1989
Dilevalol compared with propranolol and placebo for systemic hypertension.
    The American journal of cardiology, 1989, Jun-05, Volume: 63, Issue:19

    Topics: Aged; Double-Blind Method; Drug Administration Schedule; Female; Heart Rate; Humans; Hypertension; Labetalol; Male; Middle Aged; Multicenter Studies as Topic; Propranolol; Random Allocation; Supination

1989
Labetalol compared with propranolol in patients with both angina pectoris and systemic hypertension: a double-blind study.
    Journal of clinical pharmacology, 1989, Volume: 29, Issue:6

    Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Exercise Test; Female; Heart Rate; Humans; Hypertension; Labetalol; Male; Middle Aged; Propranolol; Random Allocation

1989
A multicenter double-blind study of the efficacy and safety of once and twice daily dilevalol compared to propranolol.
    American journal of hypertension, 1989, Volume: 2, Issue:11 Pt 1

    Topics: Adolescent; Adult; Aged; Blood Pressure; Double-Blind Method; Drug Administration Schedule; Female; Humans; Hypertension; Labetalol; Male; Middle Aged; Multicenter Studies as Topic; Propranolol; Randomized Controlled Trials as Topic

1989
Effects of two beta-antagonists (dilevalol and propranolol) on retinal blood flow: a double-blind placebo-controlled study.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1989, Volume: 7, Issue:6

    Topics: Adult; Blood Pressure; Double-Blind Method; Female; Heart Rate; Humans; Labetalol; Male; Placebos; Propranolol; Randomized Controlled Trials as Topic; Reference Values; Regional Blood Flow; Retinal Vessels

1989
Beta blockade by oral propranolol and labetalol.
    Clinical pharmacology and therapeutics, 1985, Volume: 37, Issue:3

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Blood Pressure; Double-Blind Method; Ethanolamines; Heart Rate; Humans; Injections, Intravenous; Isometric Contraction; Isoproterenol; Labetalol; Male; Propranolol; Random Allocation

1985
Comparative effects of adimolol, labetalol and propranolol on heart rate and blood pressure in man.
    British journal of clinical pharmacology, 1985, Volume: 19, Issue:4

    Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Dose-Response Relationship, Drug; Ethanolamines; Heart Rate; Humans; Labetalol; Male; Phenylephrine; Physical Exertion; Propanolamines; Propranolol; Time Factors

1985
Beta blockade and intermittent claudication.
    Acta medica Scandinavica. Supplementum, 1985, Volume: 700

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Clinical Trials as Topic; Coronary Disease; Female; Gait; Hemodynamics; Humans; Hypertension; Intermittent Claudication; Labetalol; Leg; Male; Metoprolol; Middle Aged; Physical Exertion; Pindolol; Propranolol; Risk

1985
Comparative effects of beta-, alpha- and combined beta- plus alpha-adrenoceptor blocking agents in stress-induced increase in arterial blood pressure.
    International journal of clinical pharmacology, therapy, and toxicology, 1987, Volume: 25, Issue:6

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Atenolol; Blood Pressure; Cold Temperature; Double-Blind Method; Heart Rate; Humans; Isometric Contraction; Labetalol; Male; Prazosin; Propranolol; Random Allocation; Stress, Physiological

1987
Vasodilating mechanism and response to physiological pressor stimuli of acute doses of carvedilol compared with labetalol, propranolol and hydralazine.
    Drugs, 1988, Volume: 36 Suppl 6

    Topics: Adrenergic beta-Antagonists; Adult; Angiotensin II; Antihypertensive Agents; Blood Pressure; Carbazoles; Carvedilol; Cold Temperature; Double-Blind Method; Exercise; Heart Rate; Hemodynamics; Humans; Hydralazine; Isoproterenol; Labetalol; Male; Middle Aged; Phenylephrine; Posture; Propanolamines; Propranolol; Vasodilator Agents

1988
[Effect of obsidan and labetalol on the course of myocardial infarction].
    Vrachebnoe delo, 1988, Issue:6

    Topics: Adult; Aged; Clinical Trials as Topic; Humans; Labetalol; Male; Middle Aged; Myocardial Infarction; Propranolol

1988
Cost effectiveness of labetalol and propranolol in the treatment of hypertension among blacks.
    Journal of the National Medical Association, 1987, Volume: 79, Issue:10

    Topics: Aged; Black People; Clinical Trials as Topic; Cost-Benefit Analysis; Female; Humans; Hypertension; Labetalol; Male; Middle Aged; Propranolol

1987
Labetalol compared with propranolol in the treatment of black hypertensive patients.
    Journal of clinical hypertension, 1987, Volume: 3, Issue:3

    Topics: Adolescent; Adult; Aged; Black People; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Labetalol; Lipids; Male; Middle Aged; Propranolol; Prospective Studies; Random Allocation

1987
Comparative effect of propranolol and labetalol on isometric exercise and cold stress induced increase in arterial blood pressure.
    International journal of clinical pharmacology, therapy, and toxicology, 1986, Volume: 24, Issue:5

    Topics: Adult; Blood Pressure; Clinical Trials as Topic; Cold Temperature; Double-Blind Method; Heart Rate; Humans; Labetalol; Male; Physical Exertion; Posture; Propranolol; Stress, Physiological

1986
Management of ventricular arrhythmias associated with mitral valve prolapse by combined alpha and beta blockade.
    Postgraduate medical journal, 1986, Volume: 62, Issue:726

    Topics: Adult; Aged; Arrhythmias, Cardiac; Electrocardiography; Exercise Test; Female; Humans; Isometric Contraction; Labetalol; Male; Middle Aged; Mitral Valve Prolapse; Propranolol; Valsalva Maneuver

1986
The effects of single-dose atenolol, labetalol, and propranolol on cardiac and vascular function.
    Clinical pharmacology and therapeutics, 1986, Volume: 40, Issue:3

    Topics: Aged; Atenolol; Cardiac Output; Cardiovascular System; Heart Rate; Humans; Hypertension; Labetalol; Male; Middle Aged; Propranolol; Vascular Resistance

1986
Chronic effects of labetalol, pindolol, and propranolol on calf blood flow in intermittent claudication.
    Clinical pharmacology and therapeutics, 1985, Volume: 37, Issue:1

    Topics: Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Ethanolamines; Heart Rate; Humans; Intermittent Claudication; Labetalol; Leg; Male; Middle Aged; Pindolol; Propranolol; Random Allocation; Vascular Resistance

1985
A double-blind crossover clinical trial of labetalol and propranolol in patients of essential hypertension.
    International journal of clinical pharmacology, therapy, and toxicology, 1985, Volume: 23, Issue:2

    Topics: Clinical Trials as Topic; Double-Blind Method; Ethanolamines; Female; Humans; Hypertension; Labetalol; Male; Middle Aged; Propranolol

1985
Propranolol versus labetalol: interesting differences in efficacy.
    Journal of the National Medical Association, 1985, Volume: 77 Suppl

    Topics: Adult; Aged; Black People; Clinical Trials as Topic; Double-Blind Method; Ethanolamines; Humans; Hypertension; Labetalol; Middle Aged; Propranolol

1985
Comparison of the effects of labetalol and hydrochlorothiazide on the ventilatory function of hypertensive patients with asthma and propranolol sensitivity.
    Chest, 1985, Volume: 88, Issue:6

    Topics: Adolescent; Adult; Aged; Asthma; Clinical Trials as Topic; Drug Evaluation; Female; Forced Expiratory Volume; Humans; Hydrochlorothiazide; Hypertension; Labetalol; Male; Middle Aged; Propranolol; Respiration

1985
Monotherapy with labetalol compared with propranolol. Differential effects by race.
    Journal of clinical hypertension, 1985, Volume: 1, Issue:1

    Topics: Adult; Aged; Black or African American; Bradycardia; Clinical Trials as Topic; Dizziness; Double-Blind Method; Drug Therapy, Combination; Fatigue; Female; Humans; Hydrochlorothiazide; Labetalol; Male; Middle Aged; Propranolol; Sexual Dysfunction, Physiological; White People

1985
Effects of atenolol, labetalol and propranolol on the peripheral circulation in hypertensive patients without obstructive vascular disease.
    European journal of clinical pharmacology, 1985, Volume: 28, Issue:2

    Topics: Adolescent; Adult; Atenolol; Blood Circulation; Ethanolamines; Female; Fingers; Humans; Hypertension; Labetalol; Male; Middle Aged; Plethysmography; Propranolol; Regional Blood Flow

1985
Influence of labetalol, propranolol and practolol in patients with asthma.
    European journal of respiratory diseases, 1982, Volume: 63, Issue:3

    Topics: Adolescent; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Asthma; Bronchi; Ethanolamines; Female; Forced Expiratory Volume; Humans; Labetalol; Male; Middle Aged; Practolol; Propranolol

1982
Beta-adrenoceptor blockade and psychic stress in man. A comparison of the acute effects of labetalol, metoprolol, pindolol and propranolol on plasma levels of adrenaline and noradrenaline.
    British journal of clinical pharmacology, 1982, Volume: 13, Issue:Suppl 2

    Topics: Adrenergic beta-Antagonists; Adult; Catecholamines; Epinephrine; Humans; Labetalol; Male; Metoprolol; Norepinephrine; Pindolol; Propranolol; Stress, Psychological

1982
Labetalol, beta blockers, and acute deterioration of chronic airway obstruction.
    Clinical and experimental hypertension. Part A, Theory and practice, 1982, Volume: 4, Issue:8

    Topics: Adrenergic beta-Antagonists; Aged; Atenolol; Ethanolamines; Humans; Hypertension; Labetalol; Lung Diseases, Obstructive; Lung Volume Measurements; Metoprolol; Middle Aged; Propranolol

1982
[Comparative evaluation of the therapeutic effect of various classes of beta-blockaders in patients with hypertension].
    Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR, 1983, Volume: 6, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Clinical Trials as Topic; Echocardiography; Heart; Hemodynamics; Humans; Hypertension; Labetalol; Middle Aged; Nadolol; Propanolamines; Propranolol

1983
Propranolol vs metoprolol vs labetalol: a comparative study in essential hypertension.
    European journal of clinical pharmacology, 1984, Volume: 26, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Double-Blind Method; Female; Humans; Hypertension; Isometric Contraction; Labetalol; Male; Metoprolol; Middle Aged; Peak Expiratory Flow Rate; Propranolol

1984
Beta-blockade in ischaemic heart disease--influence of concomitant ISA or alpha-blockade on haemodynamic profile.
    Postgraduate medical journal, 1983, Volume: 59 Suppl 3

    Topics: Adult; Clinical Trials as Topic; Coronary Disease; Dose-Response Relationship, Drug; Ethanolamines; Hemodynamics; Humans; Labetalol; Male; Middle Aged; Pindolol; Propranolol; Random Allocation

1983
Haemodynamic advantages of combined alpha-blockade and beta-blockade over beta-blockade alone in patients with coronary heart disease.
    British medical journal (Clinical research ed.), 1982, Jul-31, Volume: 285, Issue:6338

    Topics: Adult; Blood Pressure; Cardiac Output; Coronary Disease; Ethanolamines; Hemodynamics; Humans; Labetalol; Male; Middle Aged; Physical Exertion; Propranolol; Random Allocation

1982
Labetalol and propranolol in mild hypertensives: comparison of blood pressure and plasma volume effects.
    Australian and New Zealand journal of medicine, 1980, Volume: 10, Issue:2

    Topics: Adult; Aged; Blood Pressure; Body Weight; Drug Therapy, Combination; Ethanolamines; Female; Humans; Hypertension; Labetalol; Male; Middle Aged; Plasma Volume; Posture; Propranolol

1980
Relation between ST-depression and chest pain in patients with coronary heart disease receiving no treatment and after beta-blockade and combined alpha-beta-blockade.
    Acta medica Scandinavica. Supplementum, 1981, Volume: 644

    Topics: Aged; Angina Pectoris; Blood Pressure; Coronary Disease; Electrocardiography; Ethanolamines; Exercise Test; Heart Rate; Humans; Labetalol; Male; Middle Aged; Propranolol

1981
Labetalol in the treatment of hypertension in patients with normal and impaired renal function.
    Acta medica Scandinavica. Supplementum, 1982, Volume: 665

    Topics: Adult; Aged; Double-Blind Method; Ethanolamines; Female; Half-Life; Humans; Hypertension; Kidney Diseases; Kinetics; Labetalol; Male; Middle Aged; Propranolol

1982
Effects of labetalol and propranolol on the peripheral circulation in hypertensive patients.
    Acta medica Scandinavica. Supplementum, 1982, Volume: 665

    Topics: Adult; Aged; Blood Pressure; Double-Blind Method; Ethanolamines; Extremities; Female; Humans; Hypertension; Labetalol; Male; Middle Aged; Muscle Contraction; Plethysmography; Propranolol; Random Allocation; Regional Blood Flow; Vascular Resistance

1982
Comparison of labetalol and propranolol in hypertension.
    British journal of clinical pharmacology, 1980, Volume: 9, Issue:3

    Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Ethanolamines; Female; Humans; Hypertension; Labetalol; Male; Middle Aged; Propranolol; Time Factors

1980
Comparison of labetalol, hydrallazine, and propranolol in the therapy of moderate hypertension.
    The Medical journal of Australia, 1980, Mar-08, Volume: 1, Issue:5

    Topics: Antihypertensive Agents; Clinical Trials as Topic; Drug Therapy, Combination; Ethanolamines; Female; Heart Rate; Humans; Hydralazine; Hypertension; Labetalol; Male; Middle Aged; Placebos; Propranolol

1980
Comparison of labetalol, propranolol and hydralazine in hypertensive out-patients.
    European journal of clinical pharmacology, 1982, Volume: 21, Issue:6

    Topics: Adult; Clinical Trials as Topic; Drug Therapy, Combination; Ethanolamines; Female; Humans; Hydralazine; Hypertension; Labetalol; Male; Middle Aged; Propranolol; Time Factors

1982
Renal haemodynamics after chronic treatment with labetalol and propranolol.
    British journal of clinical pharmacology, 1982, Volume: 13, Issue:1 Suppl

    Topics: Adult; Aged; Blood Pressure; Ethanolamines; Female; Heart Rate; Humans; Hypertension; Labetalol; Male; Middle Aged; Physical Exertion; Placebos; Propranolol; Renal Circulation

1982
Comparative haemodynamic dose response effects of propranolol and labetalol in coronary heart disease.
    British heart journal, 1982, Volume: 48, Issue:4

    Topics: Adult; Coronary Disease; Dose-Response Relationship, Drug; Ethanolamines; Heart Ventricles; Hemodynamics; Humans; Labetalol; Male; Middle Aged; Physical Exertion; Propranolol

1982
[Comparative study of labetolol and propranolol in patients with untreated hypertension].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1981, Mar-30, Volume: 101, Issue:9-10

    Topics: Adult; Aged; Double-Blind Method; Ethanolamines; Female; Humans; Hypertension; Labetalol; Male; Middle Aged; Propranolol

1981
The effect of labetalol and propranolol on the pressor response to sexual arousal in women.
    British journal of clinical pharmacology, 1981, Volume: 12, Issue:3

    Topics: Adult; Arousal; Blood Pressure; Ethanolamines; Female; Humans; Labetalol; Orgasm; Propranolol

1981
Comparison of the effects of dilevalol and propranolol on systemic and regional haemodynamics in healthy volunteers at rest and during exercise.
    European journal of clinical pharmacology, 1994, Volume: 47, Issue:1

    Topics: Adult; Atrial Natriuretic Factor; Cross-Over Studies; Double-Blind Method; Exercise; Hemodynamics; Humans; Labetalol; Male; Norepinephrine; Propranolol; Regional Blood Flow; Renin; Rest

1994
Pharmacokinetics of beta-adrenoceptor blockers in obese and normal volunteers.
    British journal of clinical pharmacology, 1997, Volume: 43, Issue:6

    Topics: Adipose Tissue; Adrenergic beta-Antagonists; Adult; Area Under Curve; Benzopyrans; Binding Sites; Bisoprolol; Blood Chemical Analysis; Blood Pressure; Cardiac Output; Chromatography, High Pressure Liquid; Ethanolamines; Female; Heart Rate; Humans; Hydrogen-Ion Concentration; Infusions, Intravenous; Labetalol; Male; Nebivolol; Obesity; Propranolol; Regression Analysis; Sotalol; Stereoisomerism; Tissue Distribution

1997

Other Studies

146 other study(ies) available for labetalol and propranolol

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes.
    Journal of medicinal chemistry, 2001, Mar-15, Volume: 44, Issue:6

    Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water

2001
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
The selectivity of beta-adrenoceptor antagonists at the human beta1, beta2 and beta3 adrenoceptors.
    British journal of pharmacology, 2005, Volume: 144, Issue:3

    Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Algorithms; Animals; Cell Line; CHO Cells; Cricetinae; Dioxoles; Humans; Propanolamines; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Receptors, Adrenergic, beta-3

2005
QSAR study on permeability of hydrophobic compounds with artificial membranes.
    Bioorganic & medicinal chemistry, 2007, Jun-01, Volume: 15, Issue:11

    Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship

2007
Molecular characteristics for solid-state limited solubility.
    Journal of medicinal chemistry, 2008, May-22, Volume: 51, Issue:10

    Topics: Chemical Phenomena; Chemistry, Physical; Molecular Structure; Multivariate Analysis; Pharmaceutical Preparations; Regression Analysis; Solubility

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Importance of physicochemical properties for the design of new pesticides.
    Journal of agricultural and food chemistry, 2011, Apr-13, Volume: 59, Issue:7

    Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic

2011
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
Hepatic pharmacokinetics of cationic drugs in a high-fat emulsion-induced rat model of nonalcoholic steatohepatitis.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Cations; Cytochrome P-450 Enzyme System; Disease Models, Animal; Emulsions; Fats; Fatty Liver; Liver; Liver Cirrhosis; Male; Non-alcoholic Fatty Liver Disease; Rats; Rats, Wistar

2011
Potent farnesyltransferase inhibitors with 1,4-diazepane scaffolds as novel destabilizing microtubule agents in hormone-resistant prostate cancer.
    Journal of medicinal chemistry, 2011, Mar-10, Volume: 54, Issue:5

    Topics: Androgen Antagonists; Azepines; Cell Line; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Farnesyltranstransferase; Humans; Hydrophobic and Hydrophilic Interactions; Male; Models, Molecular; Prostatic Neoplasms; Structure-Activity Relationship; Tubulin; Tubulin Modulators

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Lysosomal sequestration (trapping) of lipophilic amine (cationic amphiphilic) drugs in immortalized human hepatocytes (Fa2N-4 cells).
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:4

    Topics: Adrenergic beta-Antagonists; Amines; Ammonium Chloride; Antidepressive Agents, Tricyclic; Atorvastatin; Cell Line, Transformed; Diuretics; Hepatocytes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imipramine; Lysosomes; Monensin; Nigericin; Propranolol; Pyrroles

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Coumarin carboxylic acids as monocarboxylate transporter 1 inhibitors: In vitro and in vivo studies as potential anticancer agents.
    Bioorganic & medicinal chemistry letters, 2016, 07-15, Volume: 26, Issue:14

    Topics: Animals; Antineoplastic Agents; Carboxylic Acids; Cell Line, Tumor; Cell Proliferation; Coumarins; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Humans; Mammary Neoplasms, Experimental; Mice; Molecular Structure; Monocarboxylic Acid Transporters; Structure-Activity Relationship; Symporters

2016
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Alkynyl-containing phenylthiazoles: Systemically active antibacterial agents effective against methicillin-resistant Staphylococcus aureus (MRSA).
    European journal of medicinal chemistry, 2018, Mar-25, Volume: 148

    Topics: Alkynes; Animals; Anti-Bacterial Agents; Half-Life; Methicillin-Resistant Staphylococcus aureus; Mice; Microsomes, Liver; Staphylococcal Infections; Thiazoles

2018
Drug repurposing and rediscovery: Design, synthesis and preliminary biological evaluation of 1-arylamino-3-aryloxypropan-2-ols as anti-melanoma agents.
    Bioorganic & medicinal chemistry, 2020, 05-01, Volume: 28, Issue:9

    Topics: Antineoplastic Agents; Apoptosis; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Discovery; Drug Repositioning; Drug Screening Assays, Antitumor; Humans; Melanoma; Molecular Docking Simulation; Molecular Structure; Propanols; Skin Neoplasms; Structure-Activity Relationship; Tumor Cells, Cultured

2020
Labetalol, an alpha- and beta-adrenergic blocking drug in the treatment of hypertension.
    American heart journal, 1977, Volume: 93, Issue:1

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Blood Pressure; Ethanolamines; Humans; Hypertension; Labetalol; Pheochromocytoma; Propranolol

1977
Labetalol (AH5158), a competitive alpha- and beta-receptor blocking drug, in the management of hypertension.
    Australian and New Zealand journal of medicine, 1976, Volume: 6, Issue:3 Suppl

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aldosterone; Angiotensin II; Clonidine; Ethanolamines; Female; Humans; Hypertension; Labetalol; Male; Middle Aged; Pheochromocytoma; Propranolol; Substance Withdrawal Syndrome

1976
Adrenoceptor blockade of the circulatory responses to intravenous isoproterenol.
    Clinical pharmacology and therapeutics, 1978, Volume: 24, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Cardiac Output; Heart Rate; Hemodynamics; Humans; Isoproterenol; Labetalol; Male; Myocardial Contraction; Phentolamine; Propranolol; Stroke Volume; Time Factors

1978
Effects of the beta-receptor antagonists propranolol, oxprenolol and labetalol on human vascular smooth-muscle contraction.
    Clinical science and molecular medicine, 1978, Volume: 55, Issue:3

    Topics: Adrenergic beta-Antagonists; Arteries; Barium; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Labetalol; Muscle Contraction; Muscle, Smooth; Norepinephrine; Oxprenolol; Propranolol; Serotonin Antagonists

1978
Hypotensive and vascular effects of labetalol in the normotensive rat and dog.
    Japanese heart journal, 1978, Volume: 19, Issue:5

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Flow Velocity; Blood Pressure; Dogs; Ethanolamines; Female; Femoral Artery; Heart Rate; Isoproterenol; Kidney; Labetalol; Male; Phentolamine; Propranolol; Rats; Regional Blood Flow; Vasomotor System

1978
Reactivity of the cardiovascular system in the tetraplegic patient.
    Clinical pharmacology and therapeutics, 1979, Volume: 26, Issue:3

    Topics: Adrenergic beta-Antagonists; Atropine; Blood Pressure; Electrocardiography; Guanethidine; Heart Rate; Hemodynamics; Humans; Labetalol; Male; Nitroglycerin; Phenoxybenzamine; Posture; Propranolol; Quadriplegia; Sympathetic Nervous System; Systole

1979
Labetalol possesses beta-adrenoceptor agonist action on the rat isolated uterus.
    The Journal of pharmacy and pharmacology, 1979, Volume: 31, Issue:11

    Topics: Adrenergic beta-Agonists; Animals; Estrus; Ethanolamines; Female; In Vitro Techniques; Isoproterenol; Labetalol; Pregnancy; Propranolol; Rats; Uterine Contraction

1979
The influence of calcium on the antilipolytic action of propranolol, timolol, labetalol, verapamil, procaine, and papaverine in rat adipocytes.
    Pharmacological research communications, 1979, Volume: 11, Issue:9

    Topics: Adipose Tissue; Adrenergic beta-Antagonists; Adrenocorticotropic Hormone; Animals; Calcium; In Vitro Techniques; Isoproterenol; Labetalol; Lipolysis; Male; Papaverine; Procaine; Propranolol; Rats; Timolol; Vasodilator Agents; Verapamil

1979
Combined alpha- and beta-adrenoceptor blocking drug AH 5158: further studies on alpha-adrenoceptor blockade in anaesthetized animals.
    British journal of pharmacology, 1975, Volume: 53, Issue:4

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthesia; Animals; Blood Pressure; Cats; Cocaine; Dogs; Drug Interactions; Ethanolamines; Female; Heart Rate; Labetalol; Male; Norepinephrine; Phenylephrine; Propranolol; Rats; Spinal Cord

1975
Paroxysmal neurogenic hypertension and its prevention in patients with cervical spinal cord lesions.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1979, Jul-07, Volume: 56, Issue:1

    Topics: Adult; Blood Pressure; Ethanolamines; Heart Rate; Humans; Hypertension; Labetalol; Middle Aged; Norepinephrine; Phenoxybenzamine; Propranolol; Pulse; Quadriplegia; Reflex, Abnormal

1979
Adrenoceptor mechanisms in the cardiovascular effects of cocaine in conscious squirrel monkeys.
    Life sciences, 1992, Volume: 51, Issue:9

    Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Blood Pressure; Cocaine; Heart Rate; Labetalol; Male; Phentolamine; Prazosin; Propanolamines; Propranolol; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Saimiri; Yohimbine

1992
Study of the glycogenolytic action of platelet activating factor in Tetrahymena pyriformis.
    Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology, 1992, Volume: 102, Issue:3

    Topics: Animals; Atenolol; Calcium; Cyclic AMP; Glucose; Glycogen; Labetalol; Platelet Activating Factor; Propranolol; Tetrahymena pyriformis

1992
Effect of oral dilevalol on forearm circulation in essential hypertension.
    Journal of cardiovascular pharmacology, 1992, Volume: 19, Issue:3

    Topics: Administration, Oral; Antihypertensive Agents; Blood Pressure; Female; Forearm; Heart Rate; Humans; Hypertension; Infusions, Intra-Arterial; Labetalol; Male; Middle Aged; Propranolol; Regional Blood Flow; Time Factors; Vascular Resistance

1992
Changes in adrenoceptors and monoamine metabolism in neonatal and adult rat brain after postnatal exposure to the antihypertensive labetalol.
    British journal of pharmacology, 1992, Volume: 105, Issue:1

    Topics: Animals; Animals, Newborn; Biogenic Amines; Body Weight; Brain; Labetalol; Organ Size; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic

1992
Response to beta-blockers in maternal and fetal rat hearts in vitro.
    Life sciences, 1991, Volume: 48, Issue:18

    Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Female; Heart; Heart Rate; Isoproterenol; Labetalol; Metoprolol; Pregnancy; Pregnancy, Animal; Propranolol; Rats; Rats, Inbred Strains

1991
The alpha- and beta-adrenoceptor blocking activities of labetalol and its RR-SR (50:50) stereoisomers.
    British journal of pharmacology, 1991, Volume: 104, Issue:4

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Cerebral Cortex; Dose-Response Relationship, Drug; Heart; Heart Rate; In Vitro Techniques; Isoproterenol; Labetalol; Male; Myocardium; Phenylephrine; Prazosin; Propranolol; Rats; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Stereoisomerism

1991
Comparative effects of arotinolol, labetalol and propranolol on regional myocardial dysfunction induced by flow-limiting coronary stenosis in anesthetized dogs.
    Japanese journal of pharmacology, 1990, Volume: 53, Issue:3

    Topics: Adrenergic beta-Antagonists; Anesthesia; Animals; Blood Pressure; Cardiomyopathies; Coronary Vessels; Dogs; Female; Heart Rate; Hemodynamics; Isoproterenol; Labetalol; Male; Myocardial Contraction; Phenylephrine; Propanolamines; Propranolol

1990
Prevention of cerebral stroke by arotinolol in salt-loaded SHRSP.
    Clinical and experimental hypertension. Part A, Theory and practice, 1991, Volume: 13, Issue:5

    Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Brain; Cerebrovascular Disorders; Disease Susceptibility; Hypertension; Labetalol; Male; Pindolol; Propanolamines; Propranolol; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium, Dietary

1991
Effects of dilevalol on adrenoceptors in isolated cat arteries.
    Journal of pharmacobio-dynamics, 1990, Volume: 13, Issue:11

    Topics: Animals; Arteries; Cats; Clonidine; Dinoprost; Electric Stimulation; Female; In Vitro Techniques; Labetalol; Male; Norepinephrine; Phenylephrine; Prazosin; Propranolol; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Vasoconstriction; Yohimbine

1990
Inhibition of hypothalamic somatostatin release by beta-adrenergic antagonists.
    Endocrinology, 1990, Volume: 126, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Cells, Cultured; Clonidine; Growth Hormone; Hypothalamus; Labetalol; Male; Metoprolol; Ouabain; Pituitary Gland, Anterior; Propranolol; Rats; Rats, Inbred Strains; Somatostatin

1990
Effects of four beta-adrenergic receptor antagonists on male rat sexual behavior.
    Pharmacology, biochemistry, and behavior, 1990, Volume: 36, Issue:4

    Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Dose-Response Relationship, Drug; Labetalol; Male; Pindolol; Propranolol; Rats; Sexual Behavior, Animal

1990
[The use of labetalol and propranolol in patients who have had a myocardial infarct].
    Vrachebnoe delo, 1990, Issue:5

    Topics: Adult; Drug Evaluation; Exercise Test; Humans; Labetalol; Middle Aged; Myocardial Infarction; Physical Endurance; Propranolol; Recurrence

1990
Cardiac alpha-adrenoceptors: postjunctional and prejunctional.
    Journal of molecular and cellular cardiology, 1986, Volume: 18 Suppl 5

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic alpha-Antagonists; Animals; Calcium; Dioxanes; Dose-Response Relationship, Drug; Female; Heart Conduction System; Heart Rate; Idazoxan; In Vitro Techniques; Labetalol; Methoxamine; Myocardial Contraction; Myocardium; Norepinephrine; Phenylephrine; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Stimulation, Chemical; Verapamil

1986
Effects of the antihypertensive dilevalol on large artery compliance in anesthetized dogs.
    Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 11

    Topics: Animals; Aorta; Blood Pressure; Compliance; Dogs; Female; Labetalol; Male; Pindolol; Propranolol; Ultrasonography

1987
Effects of the antihypertensive dilevalol on aortic compliance in anesthetized dogs.
    Journal of cardiovascular pharmacology, 1988, Volume: 12, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Aorta, Abdominal; Compliance; Dogs; Female; Labetalol; Male; Propranolol; Vasodilator Agents

1988
Cellular electrophysiology and beta-adrenergic-blocking activity of dilevalol, the R,R-isomer of labetalol, on isolated canine cardiac tissues.
    Journal of cardiovascular pharmacology, 1989, Volume: 14, Issue:3

    Topics: Action Potentials; Adrenergic beta-Antagonists; Animals; Dogs; Electrophysiology; Heart; Heart Rate; In Vitro Techniques; Labetalol; Membrane Potentials; Microelectrodes; Muscles; Propranolol; Purkinje Fibers; Stereoisomerism

1989
Effects of dilevalol on forearm circulation in essential hypertension.
    The American journal of cardiology, 1989, Jun-05, Volume: 63, Issue:19

    Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Adult; Female; Forearm; Hemodynamics; Humans; Hypertension; Infusions, Intra-Arterial; Isoproterenol; Labetalol; Male; Middle Aged; Propranolol; Regional Blood Flow

1989
Cocaine, pulmonary edema, and propranolol.
    Annals of internal medicine, 1989, May-15, Volume: 110, Issue:10

    Topics: Animals; Cocaine; Humans; Labetalol; Propranolol; Pulmonary Edema

1989
Non-resectable phaeochromocytoma: long term follow-up.
    Journal of human hypertension, 1989, Volume: 3, Issue:2

    Topics: Adrenal Gland Neoplasms; Adult; Antineoplastic Combined Chemotherapy Protocols; Aortography; Female; Humans; Labetalol; Phenoxybenzamine; Pheochromocytoma; Propranolol; Time Factors; Tomography, X-Ray Computed; Venae Cavae

1989
[Circadian rise of blood pressure and combined alpha-beta adrenoceptor blockade].
    Deutsche medizinische Wochenschrift (1946), 1985, Mar-08, Volume: 110, Issue:10

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Circadian Rhythm; Cold Temperature; Drug Therapy, Combination; Humans; Hypertension; Indoramin; Labetalol; Prazosin; Propranolol

1985
Autonomic and antihypertensive activity of oral amosulalol (YM-09538), a combined alpha- and beta-adrenoceptor blocking agent in conscious rats.
    Japanese journal of pharmacology, 1985, Volume: 38, Issue:1

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Autonomic Nervous System; Blood Pressure; Ethanolamines; Heart Rate; Isoproterenol; Labetalol; Male; Phenylephrine; Prazosin; Propranolol; Rats; Rats, Inbred SHR; Rats, Inbred Strains

1985
Inhibition of thromboxane and prostacyclin production in whole blood by adrenoceptor antagonists.
    Prostaglandins, leukotrienes, and medicine, 1985, Volume: 19, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Atenolol; Epoprostenol; Humans; Labetalol; Pindolol; Propranolol; Thromboxane A2; Thromboxane B2

1985
A comparative study of the effects of adrenoceptor antagonists on platelet aggregation and thromboxane generation.
    Thrombosis and haemostasis, 1985, Aug-30, Volume: 54, Issue:2

    Topics: Adrenergic beta-Antagonists; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Labetalol; Pindolol; Platelet Aggregation; Prazosin; Propranolol; Thromboxane A2; Thromboxane B2

1985
Intrinsic beta-sympathomimetic activity of dilevalol, R, R-isomer of labetalol.
    Journal of pharmacobio-dynamics, 1985, Volume: 8, Issue:9

    Topics: Adrenergic beta-Agonists; Animals; Blood Pressure; Guinea Pigs; Heart Rate; In Vitro Techniques; Labetalol; Male; Muscle Relaxation; Muscle, Smooth; Pindolol; Propranolol; Rats; Rats, Inbred Strains; Stereoisomerism; Trachea

1985
[Effect of beta-adrenergic blockaders and their combination with an alpha-adrenergic blockader on physical exertion tolerance in patients with hypertension].
    Kardiologiia, 1986, Volume: 26, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Blood Pressure; Drug Therapy, Combination; Heart Rate; Humans; Hypertension; Labetalol; Oxprenolol; Oxygen Consumption; Phentolamine; Physical Endurance; Physical Exertion; Pindolol; Propranolol; Time Factors

1986
Electrophysiological effects of amosulalol, a new alpha- and beta-adrenoceptor blocker, in isolated rabbit papillary muscles.
    European journal of pharmacology, 1986, Jun-24, Volume: 125, Issue:3

    Topics: Action Potentials; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Electric Stimulation; Ethanolamines; Female; Heart; In Vitro Techniques; Kinetics; Labetalol; Male; Papillary Muscles; Prazosin; Propranolol; Rabbits; Time Factors

1986
Endothelial potentiation of relaxation response to beta adrenoceptor blocking agents.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:3

    Topics: 5,8,11,14-Eicosatetraynoic Acid; Adrenergic beta-Antagonists; Animals; Aorta, Thoracic; Dinoprost; Dose-Response Relationship, Drug; Drug Synergism; Endothelium; Labetalol; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Propanolamines; Propranolol; Prostaglandin Endoperoxides, Synthetic; Prostaglandins F; Pyridines; Rats; Rats, Inbred Strains; Spiro Compounds; Timolol; Vasodilation

1986
Labetalol protects against the potentiation by propranolol of the bronchospasm to norepinephrine in guinea-pigs.
    Archives internationales de pharmacodynamie et de therapie, 1987, Volume: 285, Issue:1

    Topics: Adrenergic alpha-Agonists; Animals; Bronchial Spasm; Drug Interactions; Guinea Pigs; Labetalol; Male; Norepinephrine; Propranolol

1987
Lipophilic beta-adrenoceptor antagonists stimulate cholesterol biosynthesis in human skin fibroblasts.
    Biochemical pharmacology, 1987, Jun-15, Volume: 36, Issue:12

    Topics: Adrenergic beta-Antagonists; Cholesterol; Fibroblasts; Humans; Hydroxymethylglutaryl CoA Reductases; Labetalol; Metoprolol; Pindolol; Propanolamines; Propranolol; Skin; Stereoisomerism

1987
Failure of enhancement by labetalol of bronchopulmonary effects of histamine in guinea-pigs: independence of alpha-adrenoceptor antagonism.
    British journal of pharmacology, 1987, Volume: 91, Issue:3

    Topics: Adrenergic alpha-Antagonists; Animals; Bronchi; Guinea Pigs; Histamine; Labetalol; Lung; Male; Neural Conduction; Plethysmography; Prazosin; Propranolol; Respiration

1987
[The effect of dilevalol in histamine-induced airway constriction in guinea pigs].
    Arerugi = [Allergy], 1987, Volume: 36, Issue:9

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Airway Resistance; Animals; Guinea Pigs; Histamine; Labetalol; Propranolol; Respiratory Hypersensitivity; Sympathomimetics

1987
Placental transfer of beta-adrenergic antagonists studied in an in vitro perfusion system of human placental tissue.
    American journal of obstetrics and gynecology, 1988, Volume: 159, Issue:1

    Topics: Adrenergic beta-Antagonists; Atenolol; Celiprolol; Female; Humans; In Vitro Techniques; Labetalol; Maternal-Fetal Exchange; Placenta; Pregnancy; Propanolamines; Propranolol; Timolol

1988
Beta blockers inhibit fetal thromboxane A2 production in vitro.
    Biology of the neonate, 1988, Volume: 54, Issue:3

    Topics: Adrenergic beta-Antagonists; Atenolol; Blood Platelets; Female; Fetal Blood; Humans; Infant, Newborn; Kinetics; Labetalol; Metoprolol; Pregnancy; Propranolol; Thromboxane A2

1988
[Comparative characteristics of the hemodynamic and antianginal actions of obzidan and albetol in patients with stenocardia].
    Vrachebnoe delo, 1988, Issue:12

    Topics: Adrenergic beta-Antagonists; Adult; Angina Pectoris; Drug Evaluation; Exercise Test; Hemodynamics; Humans; Labetalol; Male; Middle Aged; Placebos; Propranolol

1988
The effects of vasoactive agents on the proliferation of vascular smooth muscle cells grown in vitro.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1988, Volume: 6, Issue:4

    Topics: Amiloride; Animals; Captopril; Cell Division; Cells, Cultured; Chlorpromazine; In Vitro Techniques; Labetalol; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nifedipine; Norepinephrine; Propranolol; Quinazolines; Rats; Sulfonamides

1988
[Arterial hypertension secondary to Guillain-Barré syndrome. Treatment with a labetalol and chlorpromazine combination. Apropos of a case].
    Medicina clinica, 1988, Jun-11, Volume: 91, Issue:3

    Topics: Aged; Chlorpromazine; Drug Therapy, Combination; Female; Humans; Hypertension; Labetalol; Nitroprusside; Polyradiculoneuropathy; Propranolol

1988
The role of catecholamines and glucagon on serum and liver metallothionein response to restraint stress.
    Revista espanola de fisiologia, 1987, Volume: 43, Issue:4

    Topics: Animals; Catecholamines; Glucagon; Labetalol; Liver; Male; Metallothionein; Propranolol; Rats; Rats, Inbred Strains; Restraint, Physical; Zinc

1987
Modulation of circadian rhythms in antibody and cell-mediated immunity by chemical sympathectomy.
    Annals of the New York Academy of Sciences, 1987, Volume: 496

    Topics: Adjuvants, Immunologic; Animals; Antibody Formation; Circadian Rhythm; Immunity, Cellular; Labetalol; Male; Propranolol; Rats; Rats, Inbred Strains; Sympathectomy, Chemical

1987
[Definition and significance of the area at risk in myocardial infarct and the ischemic border zone in acute myocardial infarct].
    Acta medica Austriaca. Supplement, 1986, Volume: 36

    Topics: Animals; Collateral Circulation; Coronary Circulation; Coronary Disease; Dogs; Electrolytes; Energy Metabolism; Fluorocarbons; Hemodilution; Labetalol; Myocardial Infarction; Myocardium; Oxygen Consumption; Oxygen Inhalation Therapy; Phosphates; Propranolol; Risk

1986
Effects of labetalol on renin release from rat kidney cortical slices.
    Journal of pharmacobio-dynamics, 1986, Volume: 9, Issue:11

    Topics: Animals; In Vitro Techniques; Isoproterenol; Kidney Cortex; Labetalol; Male; Norepinephrine; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Renin

1986
Effects of labetalol on in vitro preparations of the trachea and lung strips and on ventilation overflow in vivo in guinea pigs.
    Japanese journal of pharmacology, 1987, Volume: 43, Issue:3

    Topics: Acetylcholine; Aerosols; Animals; Diphenhydramine; Female; Guinea Pigs; Histamine; In Vitro Techniques; Labetalol; Lung; Male; Phentolamine; Propranolol; Respiration; Trachea

1987
Adrenoceptor blocking drugs and cold feet in intermittent claudication.
    VASA. Zeitschrift fur Gefasskrankheiten, 1986, Volume: 15, Issue:2

    Topics: Aged; Foot; Humans; Hypertension; Intermittent Claudication; Labetalol; Male; Middle Aged; Propranolol; Raynaud Disease; Skin Temperature

1986
Postmarketing comparison of labetalol and propranolol in hypertensive patients.
    Clinical therapeutics, 1986, Volume: 8, Issue:6

    Topics: Adult; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Labetalol; Male; Middle Aged; Product Surveillance, Postmarketing; Propranolol

1986
The effect of ageing and disease on tear constituents.
    Transactions of the ophthalmological societies of the United Kingdom, 1985, Volume: 104 ( Pt 4)

    Topics: Adult; Aged; Aging; Blepharitis; Ceruloplasmin; Eyelid Diseases; Humans; Immunoglobulin A; Immunoglobulin G; Keratoconjunctivitis; Labetalol; Lactoferrin; Middle Aged; Muramidase; Pemphigoid, Bullous; Practolol; Propranolol; Tears; Timolol; Xerophthalmia

1985
Inhibition of platelet aggregation in whole blood by adrenoceptor antagonists.
    Thrombosis research, 1985, Dec-01, Volume: 40, Issue:5

    Topics: Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Atenolol; Collagen; Drug Synergism; Epoprostenol; Humans; Labetalol; Pindolol; Platelet Aggregation; Propranolol; Solubility; Sympatholytics

1985
Hypertensive emergencies.
    American family physician, 1985, Volume: 32, Issue:1

    Topics: Antihypertensive Agents; Blood Pressure; Clonidine; Diazoxide; Emergencies; Humans; Hydralazine; Hypertension; Hypertension, Malignant; Labetalol; Nitroprusside; Propranolol; Risk; Trimethaphan

1985
[Cholinergic antagonism by beta-blockers. I. Spectrum of interactions].
    Bollettino della Societa italiana di biologia sperimentale, 1980, May-15, Volume: 56, Issue:9

    Topics: Abdominal Muscles; Acetylcholine; Adrenergic beta-Antagonists; Animals; Guinea Pigs; Heart; Ileum; Isoproterenol; Labetalol; Male; Metoprolol; Pindolol; Practolol; Propranolol; Receptors, Cholinergic; Sotalol

1980
[Cholinergic antagonism by beta-blockers. II. Sequence of interactions and final steady state effects].
    Bollettino della Societa italiana di biologia sperimentale, 1980, May-15, Volume: 56, Issue:9

    Topics: Acetylcholine; Adrenergic beta-Antagonists; Animals; Drug Interactions; Guinea Pigs; Heart; Isoproterenol; Labetalol; Male; Metoprolol; Practolol; Propranolol; Receptors, Cholinergic; Time Factors

1980
Arylethanolamines derived from salicylamide with alpha- and beta-adrenoceptor blocking activities. Preparation of labetalol, its enantiomers, and related salicylamides.
    Journal of medicinal chemistry, 1982, Volume: 25, Issue:6

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Chemical Phenomena; Chemistry; Dogs; Ethanolamines; Labetalol; Muscle, Smooth, Vascular; Phentolamine; Propranolol; Salicylamides; Stereoisomerism; Structure-Activity Relationship

1982
[Comparative study of the action of a series of new beta-adrenergic receptor blockaders in patients with effort angina].
    Biulleten' Vsesoiuznogo kardiologicheskogo nauchnogo tsentra AMN SSSR, 1983, Volume: 6, Issue:2

    Topics: Adrenergic beta-Antagonists; Adult; Angina Pectoris; Atenolol; Echocardiography; Exercise Test; Hemodynamics; Humans; Labetalol; Male; Middle Aged; Nadolol; Propanolamines; Propranolol

1983
Impairment of physical performance after treatment with beta blockers and alpha blockers.
    British medical journal (Clinical research ed.), 1984, Mar-03, Volume: 288, Issue:6418

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Alprenolol; Heart Rate; Humans; Hydrochlorothiazide; Labetalol; Male; Metoprolol; Physical Exertion; Pindolol; Prazosin; Propranolol; Running

1984
[Role of transmembrane ion currents in the mechanism of action of beta-adrenoblockers].
    Biulleten' eksperimental'noi biologii i meditsiny, 1984, Volume: 97, Issue:6

    Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Heart; Ion Channels; Labetalol; Oxprenolol; Pindolol; Propranolol; Rana ridibunda

1984
Effects of the R, R-isomer of labetalol, SCH 19927, in isolated tissues and in spontaneously hypertensive rats during a repeated treatment.
    Archives internationales de pharmacodynamie et de therapie, 1984, Volume: 272, Issue:2

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Aorta, Thoracic; Blood Pressure; Ethanolamines; Hypertension; In Vitro Techniques; Labetalol; Male; Norepinephrine; Phentolamine; Propranolol; Rats; Rats, Inbred SHR; Stereoisomerism; Time Factors

1984
Hypotensive effect of labetalol on intraocular pressure in rabbits: in relation to its alpha- and beta-adrenergic blocking action on the cardiovascular system.
    Archives internationales de pharmacodynamie et de therapie, 1981, Volume: 250, Issue:1

    Topics: Animals; Blood Pressure; Ethanolamines; Heart Rate; Intraocular Pressure; Labetalol; Male; Phentolamine; Propranolol; Rabbits; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta

1981
Effect of labetalol and propranolol on human cutaneous vasoconstrictor response to adrenaline.
    International journal of clinical pharmacology research, 1984, Volume: 4, Issue:1

    Topics: Adult; Epinephrine; Ethanolamines; Half-Life; Humans; Iodine Radioisotopes; Labetalol; Male; Propranolol; Skin; Temperature; Vasoconstriction

1984
Effects of labetalol and propranolol on responses to adrenaline infusion in healthy volunteers.
    International journal of clinical pharmacology research, 1984, Volume: 4, Issue:1

    Topics: Adult; Blood Pressure; Epinephrine; Ethanolamines; Heart Rate; Humans; Infusions, Parenteral; Labetalol; Male; Propranolol; Pulse

1984
Cold pressor test: a comparative study between labetalol and propranolol.
    The Journal of the Association of Physicians of India, 1983, Volume: 31, Issue:5

    Topics: Blood Pressure; Blood Pressure Determination; Cold Temperature; Ethanolamines; Female; Heart Rate; Humans; Labetalol; Male; Propranolol

1983
Comparison of haemodynamic dose-response effects of beta- and alpha-beta-blockade in acute myocardial infarction.
    International journal of cardiology, 1984, Volume: 5, Issue:3

    Topics: Aged; Cardiac Output; Dose-Response Relationship, Drug; Ethanolamines; Heart Rate; Hemodynamics; Humans; Labetalol; Middle Aged; Myocardial Infarction; Propranolol; Random Allocation; Stroke Volume; Vascular Resistance

1984
The in vitro effect of hypotensive agents on the affinity of haemoglobin for oxygen.
    Acta anaesthesiologica Scandinavica, 1984, Volume: 28, Issue:1

    Topics: Erythrocytes; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Labetalol; Nitroprusside; Oxyhemoglobins; Pentolinium Tartrate; Propranolol; Trimethaphan; Vasodilator Agents

1984
Adrenaline induced dysrhythmias: comparison of the antidysrhythmic effect of labetalol with propranolol during normocarbia and hypercarbia in halothane anaesthetized cats.
    Proceedings of the Western Pharmacology Society, 1980, Volume: 23

    Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Carbon Dioxide; Cats; Epinephrine; Ethanolamines; Halothane; Labetalol; Propranolol

1980
[Vasospastic angina pectoris complicated by ventricular fibrillation during treatment with propranolol and labetalol].
    Kardiologia polska, 1983, Volume: 26, Issue:1

    Topics: Angina Pectoris, Variant; Coronary Disease; Coronary Vasospasm; Ethanolamines; Female; Humans; Labetalol; Middle Aged; Propranolol; Ventricular Fibrillation

1983
Ocular hypotensive action of labetalol in rabbit and human eyes.
    Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie. Albrecht von Graefe's archive for clinical and experimental ophthalmology, 1981, Volume: 217, Issue:3

    Topics: Animals; Dose-Response Relationship, Drug; Ethanolamines; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Labetalol; Male; Ophthalmic Solutions; Pilocarpine; Propranolol; Rabbits; Timolol

1981
The short term effects of propranolol, atenolol and labetalol on antipyrine kinetics in normal subjects.
    British journal of clinical pharmacology, 1982, Volume: 13, Issue:6

    Topics: Adult; Antipyrine; Atenolol; Drug Interactions; Female; Half-Life; Humans; Kinetics; Labetalol; Male; Propranolol; Sympatholytics

1982
The effect of different antihypertensive therapies on plasma lipids.
    The Practitioner, 1982, Volume: 226, Issue:1367

    Topics: Aged; Bendroflumethiazide; Cholesterol; Ethanolamines; Female; Humans; Hypertension; Labetalol; Lipoproteins, HDL; Male; Middle Aged; Propranolol; Triglycerides

1982
Aortic rigidity and plasma catecholamines in essential hypertensive patients.
    Clinical and experimental hypertension. Part A, Theory and practice, 1982, Volume: 4, Issue:7

    Topics: Adult; Aged; Aorta, Thoracic; Blood Pressure; Compliance; Epinephrine; Hemodynamics; Humans; Hypertension; Labetalol; Middle Aged; Muscle, Smooth, Vascular; Norepinephrine; Phentolamine; Propranolol; Sympathetic Nervous System

1982
Adrenergic activity in systolic hypertension.
    Clinical and experimental hypertension. Part A, Theory and practice, 1982, Volume: 4, Issue:7

    Topics: Aged; Epinephrine; Female; Hemodynamics; Humans; Hypertension; Labetalol; Male; Middle Aged; Norepinephrine; Phentolamine; Propranolol; Systole

1982
Effects of Dl- and l-propranolol, labetalol, and phentolamine on rabbit iris blood flow determined by hydrogen clearance method.
    [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1982, Volume: 57, Issue:6

    Topics: Animals; Blood Pressure; Blood Volume Determination; Ethanolamines; Iris; Isomerism; Labetalol; Phentolamine; Propranolol; Rabbits; Regional Blood Flow

1982
[Effectiveness of antihypertensive treatment with labetalol as compared with the combination of hydralazine and propranolol].
    Bollettino della Societa italiana di cardiologia, 1981, Volume: 26, Issue:12

    Topics: Adult; Drug Evaluation; Drug Therapy, Combination; Ethanolamines; Female; Humans; Hydralazine; Hypertension; Labetalol; Male; Middle Aged; Propranolol

1981
Comparison of the effects of propranolol and labetalol on renal haemodynamics at rest and during exercise in essential hypertension.
    European journal of clinical pharmacology, 1980, Volume: 18, Issue:2

    Topics: Adult; Ethanolamines; Female; Glomerular Filtration Rate; Hemodynamics; Humans; Hypertension; Kidney; Labetalol; Male; Physical Exertion; Propranolol; Rest

1980
Effect of propranolol and labetalol on renal haemodynamics at rest and during exercise in essential hypertension.
    Postgraduate medical journal, 1980, Volume: 56 Suppl 2

    Topics: Blood Pressure; Ethanolamines; Female; Glomerular Filtration Rate; Heart Rate; Humans; Hypertension; Kidney; Labetalol; Male; Physical Exertion; Propranolol; Regional Blood Flow

1980
Comparison of labetalol and propranolol in treatment of hypertension.
    Postgraduate medical journal, 1980, Volume: 56 Suppl 2

    Topics: Blood Pressure; Ethanolamines; Female; Heart Rate; Humans; Hypertension; Labetalol; Male; Propranolol; Time Factors

1980
Sympathetic hyperreflexia in tetraplegics. The value of systolic time intervals in assessing drug effects.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1980, Dec-13, Volume: 58, Issue:24

    Topics: Adult; Guanethidine; Humans; Hypertension; Labetalol; Male; Middle Aged; Myocardial Contraction; Phenoxybenzamine; Propranolol; Quadriplegia; Reflex, Abnormal; Systole

1980
The dangers of unopposed beta-adrenergic blockade in phaeochromocytoma.
    Postgraduate medical journal, 1995, Volume: 71, Issue:831

    Topics: Adrenal Gland Neoplasms; Adrenergic alpha-Antagonists; Adult; Aged; Fatal Outcome; Female; Humans; Labetalol; Male; Pheochromocytoma; Propranolol

1995
Effects of beta-adrenoceptor antagonists on portal vein hypertension and ethanol-induced gastric mucosal damage in rats.
    The Journal of pharmacy and pharmacology, 1994, Volume: 46, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Ethanol; Gastric Mucosa; Hemodynamics; Hypertension, Portal; Labetalol; Male; Metoprolol; Nadolol; Pindolol; Propranolol; Rats; Rats, Sprague-Dawley; Stomach Ulcer

1994
Time-dependent efficacy of antihypertensive agents in spontaneously hypertensive rats.
    Chronobiology international, 1993, Volume: 10, Issue:6

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Captopril; Circadian Rhythm; Clonidine; Felodipine; Heart Rate; Hypertension; Labetalol; Male; Metoprolol; Oxazoles; Prazosin; Propanolamines; Propranolol; Rats; Rats, Inbred SHR; Rilmenidine; Thiophenes

1993
Role of vascular alpha-2 adrenoceptors in regulating lipid mobilization from human adipose tissue.
    The Journal of clinical investigation, 1993, Volume: 91, Issue:5

    Topics: Adipose Tissue; Adult; Analysis of Variance; Clonidine; Dose-Response Relationship, Drug; Epinephrine; Ethanol; Female; Glycerol; Humans; Hydralazine; Kinetics; Labetalol; Lipid Mobilization; Male; Nitroprusside; Propranolol; Receptors, Adrenergic, alpha; Time Factors; Yohimbine

1993
Determination of propranolol, labetalol and clenbuterol in rat brain by high-performance liquid chromatography.
    Journal of chromatography, 1993, Mar-05, Volume: 613, Issue:1

    Topics: Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Clenbuterol; Labetalol; Male; Propranolol; Rats; Rats, Wistar; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet

1993
The regulation of total creatine content in a myoblast cell line.
    Molecular and cellular biochemistry, 1996, May-24, Volume: 158, Issue:2

    Topics: Animals; Atenolol; Bucladesine; Butoxamine; Cell Line; Clenbuterol; Creatine; Energy Metabolism; Insulin; Insulin-Like Growth Factor I; Isoproterenol; Labetalol; Methoxamine; Mice; Muscle, Skeletal; Norepinephrine; Phentolamine; Propranolol; Sodium; Triiodothyronine

1996
Stereoselective interaction of drug enantiomers with human serum transferrin in capillary zone electrophoresis.
    Electrophoresis, 1996, Volume: 17, Issue:12

    Topics: Bupivacaine; Electrophoresis, Capillary; Humans; Hydrogen-Ion Concentration; Labetalol; Pharmaceutical Preparations; Promethazine; Propranolol; Stereoisomerism; Transferrin

1996
Study of propranolol and its related adrenoceptor antagonists on changes of gastric electrical parameters induced by ethanol in rats.
    Pharmacology, 1999, Volume: 58, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Butoxamine; Dose-Response Relationship, Drug; Electric Conductivity; Electrophysiology; Ethanol; Gastric Mucosa; Labetalol; Male; Metoprolol; Nadolol; Propranolol; Rats; Rats, Sprague-Dawley

1999
The effects of atropine and adrenergic antagonists on behavioral arousal in rats.
    The Journal of general psychology, 2000, Volume: 127, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Arousal; Atropine; Drug Synergism; Labetalol; Motor Activity; Phentolamine; Propranolol; Rats; Rats, Sprague-Dawley

2000
Divergent effects of different beta-blocking agents on endothelium-dependent vasodilatation in the human forearm.
    Blood pressure, 2000, Volume: 9, Issue:5

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Atenolol; Blood Pressure; Diclofenac; Endothelium, Vascular; Female; Forearm; Heart Rate; Humans; Injections, Intra-Arterial; Labetalol; Male; Methacholine Chloride; Nitroprusside; Plethysmography; Propranolol; Receptors, Adrenergic, alpha-1; Receptors, Muscarinic; Vasodilation; Vasodilator Agents

2000
Pharmacological effects of an aldehyde type alpha/beta-adrenoceptor blocking agent with vasodilating properties.
    General pharmacology, 2000, Volume: 34, Issue:6

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Aorta; Atenolol; Benzaldehydes; Blood Pressure; Cardiovascular Agents; Depression, Chemical; Dose-Response Relationship, Drug; Guinea Pigs; Heart Atria; Heart Rate; Isoproterenol; Labetalol; Mecamylamine; Models, Animal; Muscle, Smooth, Vascular; Myocardial Contraction; Propranolol; Radioligand Assay; Rats; Rats, Wistar; Regression Analysis; Stimulation, Chemical; Vasodilator Agents

2000
Electrocardiographic changes associated with beta-blocker toxicity.
    Annals of emergency medicine, 2002, Volume: 40, Issue:6

    Topics: Acebutolol; Adolescent; Adrenergic beta-Antagonists; Adult; Blood Pressure; Electrocardiography; Female; Heart Rate; Humans; Labetalol; Male; Middle Aged; Poison Control Centers; Propranolol; Prospective Studies

2002
Effect of beta-adrenergic antagonists on bioluminescence control in three species of brittlestars (Echinodermata: Ophiuroidea).
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2004, Volume: 138, Issue:1

    Topics: Adrenergic beta-Antagonists; Animals; Dose-Response Relationship, Drug; Echinodermata; Epinephrine; Labetalol; Luminescence; Potassium Chloride; Propranolol; Species Specificity

2004
Isoproterenol-induced myocardial infarction in rabbits. Protection by propranolol or labetalol: a proposed non-invasive procedure.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2004, Volume: 23, Issue:3

    Topics: Adrenergic beta-Antagonists; Animals; Electrocardiography; Isoproterenol; Labetalol; Lipid Peroxides; Male; Myocardial Infarction; Myocardium; Partial Thromboplastin Time; Propranolol; Rabbits; Vitamin E

2004
Modeling the electrophoretic mobility of beta-blockers in capillary electrophoresis using artificial neural networks.
    Farmaco (Societa chimica italiana : 1989), 2005, Volume: 60, Issue:3

    Topics: Adrenergic beta-Antagonists; Atenolol; Electrolytes; Electrophoresis, Capillary; Electrophoretic Mobility Shift Assay; Labetalol; Models, Chemical; Neural Networks, Computer; Pharmaceutical Preparations; Practolol; Predictive Value of Tests; Propranolol; Solvents; Technology, Pharmaceutical; Timolol

2005
Catecholamines mediate stress-induced increases in peripheral and central inflammatory cytokines.
    Neuroscience, 2005, Volume: 135, Issue:4

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Brain Chemistry; Catecholamines; Cytokines; Electroshock; Immunohistochemistry; Labetalol; Male; Prazosin; Propranolol; Rats; Rats, Inbred F344; Stress, Psychological; Tyrosine 3-Monooxygenase

2005
Simultaneous determination of beta-blockers in human plasma using liquid chromatography-tandem mass spectrometry.
    Biomedical chromatography : BMC, 2008, Volume: 22, Issue:7

    Topics: Acebutolol; Adrenergic beta-Antagonists; Chromatography, Liquid; Humans; Labetalol; Linear Models; Metoprolol; Pindolol; Propranolol; Sensitivity and Specificity; Tandem Mass Spectrometry

2008
Microcalorimetric and zeta potential study on binding of drugs on liposomes.
    Colloids and surfaces. B, Biointerfaces, 2010, Jul-01, Volume: 78, Issue:2

    Topics: Algorithms; Alprenolol; Binding Sites; Binding, Competitive; Calorimetry; Entropy; Kinetics; Labetalol; Liposomes; Models, Chemical; Molecular Structure; Pharmaceutical Preparations; Phosphatidylcholines; Phosphatidylglycerols; Propranolol; Tetracaine; Thermodynamics

2010
Kinetic capillary electrophoresis with mass-spectrometry detection (KCE-MS) facilitates label-free solution-based kinetic analysis of protein-small molecule binding.
    Chembiochem : a European journal of chemical biology, 2011, Nov-25, Volume: 12, Issue:17

    Topics: Alprenolol; Electrophoresis, Capillary; Kinetics; Labetalol; Mass Spectrometry; Orosomucoid; Pindolol; Propranolol; Protein Binding; Proteins; Small Molecule Libraries

2011
Hepatocellular necrosis, fibrosis and microsomal activity determine the hepatic pharmacokinetics of basic drugs in right-heart-failure-induced liver damage.
    Pharmaceutical research, 2012, Volume: 29, Issue:6

    Topics: Adrenergic Antagonists; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antipyrine; Atenolol; Cell Membrane Permeability; Cytochrome P-450 Enzyme System; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Heart Failure; Labetalol; Linear Models; Liver; Liver Cirrhosis; Liver Diseases; Male; Metabolic Clearance Rate; Metoprolol; Microsomes, Liver; Models, Biological; Necrosis; Nonlinear Dynamics; Perfusion; Propranolol; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction

2012
To block or not to block? That is the question.
    The Journal of thoracic and cardiovascular surgery, 2015, Volume: 149, Issue:4

    Topics: Adrenergic beta-Antagonists; Coronary Artery Bypass; Female; Humans; Labetalol; Male; Nebivolol; Propranolol; Radial Artery; Vasodilation; Vasodilator Agents

2015
Labetalol, nebivolol, and propranolol relax human radial artery used as coronary bypass graft.
    The Journal of thoracic and cardiovascular surgery, 2015, Volume: 149, Issue:4

    Topics: Adrenergic beta-Antagonists; Coronary Artery Bypass; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Humans; In Vitro Techniques; Labetalol; Male; Middle Aged; Nebivolol; Nitric Oxide; Nitric Oxide Synthase; Potassium Channel Blockers; Potassium Channels, Calcium-Activated; Propranolol; Radial Artery; Vasodilation; Vasodilator Agents

2015
The sympathetic nervous system is controlled by transient receptor potential vanilloid 1 in the regulation of body temperature.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2015, Volume: 29, Issue:10

    Topics: Acrylamides; Adrenergic alpha-1 Receptor Antagonists; Adrenergic beta-Antagonists; Animals; Body Temperature; Body Temperature Regulation; Bridged Bicyclo Compounds, Heterocyclic; Fever; Humans; Injections, Intraperitoneal; Injections, Subcutaneous; Labetalol; Male; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Prazosin; Propranolol; Receptors, Adrenergic, alpha-1; Receptors, Adrenergic, beta; Sympathetic Nervous System; Telemetry; TRPV Cation Channels

2015
β-Blocker Exposure in Pregnancy and Risk of Fetal Cardiac Anomalies.
    JAMA internal medicine, 2017, 06-01, Volume: 177, Issue:6

    Topics: Adrenergic beta-Antagonists; Age Factors; Arrhythmias, Cardiac; Atenolol; Body Mass Index; California; Cohort Studies; Confounding Factors, Epidemiologic; Diabetes Mellitus; Eclampsia; Female; Gestational Age; Heart Defects, Congenital; Heart Failure; Humans; Hyperlipidemias; Hypertension; Labetalol; Logistic Models; Metoprolol; Multivariate Analysis; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Pregnancy Complications, Cardiovascular; Propranolol; Retrospective Studies; Risk; Risk Factors

2017
Metoprolol, propranolol, carvedilol, or labetalol for patients with Takotsubo syndrome?
    Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2018, Volume: 28, Issue:1

    Topics: Carvedilol; Humans; Labetalol; Metoprolol; Propranolol; Takotsubo Cardiomyopathy

2018
Reply to: metoprolol, or propranolol, or carvedilol, or labetalol, for patients with takotsubo syndrome?
    Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2018, Volume: 28, Issue:1

    Topics: Carvedilol; Humans; Labetalol; Metoprolol; Propranolol; Takotsubo Cardiomyopathy

2018
Calculating Kinetic Rates and Membrane Permeability from Biased Simulations.
    The journal of physical chemistry. B, 2018, 12-13, Volume: 122, Issue:49

    Topics: Cell Membrane Permeability; Chlorpromazine; Desipramine; Domperidone; Kinetics; Labetalol; Lipid Bilayers; Loperamide; Molecular Dynamics Simulation; Molecular Structure; Propranolol; Thermodynamics; Verapamil

2018
Beta-blocker subtypes and risk of low birth weight in newborns.
    Journal of clinical hypertension (Greenwich, Conn.), 2018, Volume: 20, Issue:11

    Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Atenolol; Birth Weight; California; Female; Fetal Growth Retardation; Humans; Infant, Newborn; Infant, Small for Gestational Age; Labetalol; Male; Metoprolol; Pregnancy; Prevalence; Propranolol; Retrospective Studies

2018
Use of a non-hepatic cell line highlights limitations associated with cell-based assessment of metabolically induced toxicity.
    Drug and chemical toxicology, 2020, Volume: 43, Issue:6

    Topics: Activation, Metabolic; Cell Proliferation; Cell Survival; Chlorpromazine; Cytochrome P-450 CYP3A; Epithelial Cells; HEK293 Cells; Humans; Labetalol; Propranolol; Risk Assessment; Rosiglitazone; Substrate Specificity; Toxicity Tests

2020
Applications of shun shell column and nanocomposite sorbent for analysis of eleven anti-hypertensive in human plasma.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2020, Jun-01, Volume: 1146

    Topics: Adsorption; Antihypertensive Agents; Chromatography, High Pressure Liquid; Diltiazem; Furosemide; Humans; Hydrochlorothiazide; Irbesartan; Iron; Labetalol; Limit of Detection; Losartan; Metal Nanoparticles; Methyldopa; Nanocomposites; Polyvinyl Alcohol; Prazosin; Propranolol; Reproducibility of Results; Solid Phase Microextraction; Spironolactone; Valsartan

2020
β-Blocker Use and Risk of Mortality in Heart Failure Patients Initiating Maintenance Dialysis.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2021, Volume: 77, Issue:5

    Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Atenolol; Bisoprolol; Carvedilol; Cause of Death; Cohort Studies; Female; Heart Failure; Hospitalization; Humans; Kidney Failure, Chronic; Labetalol; Logistic Models; Male; Metoprolol; Middle Aged; Mortality; Nadolol; Proportional Hazards Models; Propranolol; Protective Factors; Renal Dialysis; Retrospective Studies; Risk; Risk Factors

2021