labetalol and phenylephrine

labetalol has been researched along with phenylephrine in 38 studies

Research

Studies (38)

Timeframe	Studies, this research(%)	All Research%
pre-1990	22 (57.89)	18.7374
1990's	11 (28.95)	18.2507
2000's	3 (7.89)	29.6817
2010's	1 (2.63)	24.3611
2020's	1 (2.63)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Brockmöller, J; Dücker, C; Jensen, O	1
Prichard, BN; Richards, DA; Tuckman, J	1
Brittain, RT; Levy, GP	1
Boakes, AJ; Knight, EJ; Prichard, BN; Richards, DA; Tuckman, J	1
Cohn, JN; Mehta, J	1
Amery, A; Billiet, L; Fagard, R; Lijnen, P; Reybrouck, T	1
Drew, GM; Hilditch, A; Levy, GP	1
Kennedy, I; Levy, GP	1
Graham, BR; Prichard, BN; Tomlinson, B; Walden, RJ	1
Latini, R; Mennini, T; Riva, E	1
Kato, T; Kinjo, N; Moromizato, H; Noguchi, K; Sakanashi, M	1
Nakajima, M; Ueda, M	1
Lathers, CM; Levin, RM; Spivey, WH; Tumer, N	1
Kazierad, DJ; Lalonde, RL; Tenero, DM	1
Chin, WP; Imai, S; Nakagawa, Y; Nakahara, H	1
Louis, WJ; Rand, MJ; Story, DF; Tung, LH	1
Colindres, RE; Cubeddu, LX; Fuenmayor, N; Powell, JR; Varin, F; Villagra, VG	2
Drummer, OH; Louis, WJ; Tung, LH	1
Harron, DW; Riddell, JG; Shanks, RG	1
Honda, K; Miyata-Osawa, A; Nakagawa, C; Shiono, K; Takenaka, T	1
Maddox, YT; Mostaghim, R; Ramwell, PW	1
Bompart, F; Graham, BR; Liu, JB; Prichard, BN; Tomlinson, B	1
Doggrell, SA; Hughes, EW	1
Hlede, M; Morandin, F; Pessina, AC; Rossi, GP; Semplicini, A	1
Elliott, HL; McLean, K; Meredith, PA; Reid, JL; Sumner, DJ	1
Durant, PA; Joucken, K	1
Amery, A; Fagard, R; Lijnen, P	1
McNeill, JH; Simpson, WW	1
Adler, G; Gress, TM; Lerch, MM; Pfaff, D; Turi, S; Weidenbach, H	1
Guy, S; McDermott, BJ; Riddell, JG; Shanks, RG; Tham, TC	1
Guy, S; McKaigue, JP; Riddell, JG; Shanks, RG; Tham, TC	1
Carpenter, RL; Guertin, SR; Kalyanaraman, M; McGlew, MJ	1
Chen, IJ; Chen, SJ; Cheng, CJ; Chiu, CC; Huang, YC; Lin, YT; Wu, BN	1
DeSouza, G; Lee, J; Vallejo, R	1
Brodie, F; Chernova, J; Ford, G; Jagger, C; James, M; Mistri, A; Potter, J; Robinson, T; Wilson, E	1

Reviews

3 review(s) available for labetalol and phenylephrine

Article	Year
A review of the animal pharmacology of labetalol, a combined alpha- and beta-adrenoceptor-blocking drug. British journal of clinical pharmacology, 1976, Volume: 3, Issue:4 Suppl 3 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Autonomic Fibers, Preganglionic; Desoxycorticosterone; Dogs; Electric Stimulation; Ethanolamines; Guinea Pigs; Hemodynamics; Hypertension; Hypertension, Renal; In Vitro Techniques; Isoproterenol; Labetalol; Male; Muscle Contraction; Muscle, Smooth; Myocardial Contraction; Phentolamine; Phenylephrine; Propranolol; Rabbits; Rats	1976
Dilevalol: an overview of its clinical pharmacology and therapeutic use in hypertension. Pharmacotherapy, 1990, Volume: 10, Issue:1 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Dogs; Heart; Hemodynamics; Humans; Hypertension; Labetalol; Lipids; Phenylephrine; Receptors, Adrenergic	1990
Cardiopulmonary compromise after use of topical and submucosal alpha-agonists: possible added complication by the use of beta-blocker therapy. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1997, Volume: 117, Issue:1 Topics: Administration, Intranasal; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Child; Epinephrine; Female; Heart Arrest; Humans; Hypertension; Intraoperative Complications; Intubation, Intratracheal; Labetalol; Male; Phenylephrine; Propanolamines; Pulmonary Edema	1997

Trials

9 trial(s) available for labetalol and phenylephrine

Article	Year
Hemodynamic effects of labetalol, an alpha and beta adrenergic blocking agent, in hypertensive subjects. Circulation, 1977, Volume: 55, Issue:2 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Amyl Nitrite; Blood Pressure; Cardiac Output; Clinical Trials as Topic; Dose-Response Relationship, Drug; Ethanolamines; Heart Rate; Hemodynamics; Humans; Hypertension; Isoproterenol; Labetalol; Male; Middle Aged; Phenylephrine; Physical Exertion; Renin; Valsalva Maneuver; Vascular Resistance	1977
Clinical pharmacology of carvedilol. The Clinical investigator, 1992, Volume: 70 Suppl 1 Topics: Adrenergic beta-Antagonists; Adult; Angiotensin II; Antihypertensive Agents; Carbazoles; Carvedilol; Dose-Response Relationship, Drug; Double-Blind Method; Hemodynamics; Humans; Labetalol; Male; Norepinephrine; Phenylephrine; Propanolamines; Vasodilator Agents	1992
Mechanism of the vasodilatory effect of carvedilol in normal volunteers: a comparison with labetalol. Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 11 Topics: Adrenergic beta-Antagonists; Angiotensin II; Blood Pressure; Carbazoles; Carvedilol; Half-Life; Heart Rate; Humans; Isoproterenol; Labetalol; Phenylephrine; Propanolamines; Random Allocation; Vasodilation	1987
Comparative effects of adimolol, labetalol and propranolol on heart rate and blood pressure in man. British journal of clinical pharmacology, 1985, Volume: 19, Issue:4 Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Dose-Response Relationship, Drug; Ethanolamines; Heart Rate; Humans; Labetalol; Male; Phenylephrine; Physical Exertion; Propanolamines; Propranolol; Time Factors	1985
Vasodilating mechanism and response to physiological pressor stimuli of acute doses of carvedilol compared with labetalol, propranolol and hydralazine. Drugs, 1988, Volume: 36 Suppl 6 Topics: Adrenergic beta-Antagonists; Adult; Angiotensin II; Antihypertensive Agents; Blood Pressure; Carbazoles; Carvedilol; Cold Temperature; Double-Blind Method; Exercise; Heart Rate; Hemodynamics; Humans; Hydralazine; Isoproterenol; Labetalol; Male; Middle Aged; Phenylephrine; Posture; Propanolamines; Propranolol; Vasodilator Agents	1988
Clinical pharmacology of carvedilol in normal volunteers. Clinical pharmacology and therapeutics, 1987, Volume: 41, Issue:1 Topics: Adult; Angiotensin II; Blood Pressure; Carbazoles; Carvedilol; Dose-Response Relationship, Drug; Heart Rate; Humans; Isoproterenol; Kinetics; Labetalol; Male; Phenylephrine; Propanolamines; Random Allocation; Receptors, Adrenergic	1987
The dose dependency of the alpha- and beta-adrenoceptor antagonist activity of carvedilol in man. British journal of clinical pharmacology, 1995, Volume: 40, Issue:1 Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Blood Pressure; Carbazoles; Carvedilol; Double-Blind Method; Exercise; Heart Rate; Humans; Isoproterenol; Labetalol; Male; Phenylephrine; Propanolamines; Vasodilator Agents	1995
The dose dependency of the alpha-adrenoceptor antagonist and beta-adrenoceptor partial agonist activity of dilevalol and labetalol in man. British journal of clinical pharmacology, 1993, Volume: 36, Issue:3 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adult; Angiotensin II; Blood Pressure; Diastole; Dose-Response Relationship, Drug; Double-Blind Method; Exercise; Fingers; Heart Rate; Humans; Labetalol; Male; Phenylephrine; Systole; Tremor; Vasoconstrictor Agents; Vasodilator Agents	1993
Controlling hypertension and hypotension immediately post stroke (CHHIPS)--a randomised controlled trial. Health technology assessment (Winchester, England), 2009, Volume: 13, Issue:9 Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Cardiotonic Agents; Cost-Benefit Analysis; Deglutition Disorders; Double-Blind Method; Female; Hospitals; Humans; Hypertension; Hypotension; Infusions, Intravenous; Labetalol; Lisinopril; Male; Middle Aged; Phenylephrine; Placebos; Stroke; Survival Analysis; Time Factors; Treatment Outcome	2009

Other Studies

26 other study(ies) available for labetalol and phenylephrine

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Identification of Novel High-Affinity Substrates of OCT1 Using Machine Learning-Guided Virtual Screening and Experimental Validation. Journal of medicinal chemistry, 2021, 03-11, Volume: 64, Issue:5 Topics: Databases, Chemical; Drug Evaluation, Preclinical; HEK293 Cells; Humans; Machine Learning; Octamer Transcription Factor-1; Organic Chemicals	2021
Assessment of alpha- and beta-adrenoceptor blocking actions of labetalol. British journal of clinical pharmacology, 1976, Volume: 3, Issue:5 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Blood Pressure; Dose-Response Relationship, Drug; Ethanolamines; Heart Rate; Humans; Isoproterenol; Labetalol; Male; Phenylephrine	1976
Pharmacological basis for antihypertensive effects of intravenous labetalol. British heart journal, 1977, Volume: 39, Issue:1 Topics: Adrenergic alpha-Antagonists; Adult; Antihypertensive Agents; Blood Pressure; Depression, Chemical; Dose-Response Relationship, Drug; Ethanolamines; Heart Rate; Humans; Isoproterenol; Labetalol; Male; Phenylephrine; Physical Exertion	1977
Response of the systemic and pulmonary circulation to alpha- and beta-receptor blockade (labetalol) at rest and during exercise in hypertensive patients. Circulation, 1979, Volume: 60, Issue:6 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Blood Circulation; Blood Pressure; Ethanolamines; Exercise Test; Female; Heart Rate; Humans; Hypertension; Labetalol; Male; Middle Aged; Phenylephrine; Pulmonary Circulation; Rest; Tachycardia	1979
The relationships between the cardiovascular effects, alpha- and beta-adrenoceptor blocking actions and plasma concentration of labetalol in doca hypertensive rats. Clinical and experimental hypertension, 1979, Volume: 1, Issue:5 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Depression, Chemical; Desoxycorticosterone; Dose-Response Relationship, Drug; Ethanolamines; Heart Rate; Hypertension; Isoproterenol; Labetalol; Male; Phenylephrine; Rats	1979
Combined alpha- and beta-adrenoceptor blocking drug AH 5158: further studies on alpha-adrenoceptor blockade in anaesthetized animals. British journal of pharmacology, 1975, Volume: 53, Issue:4 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthesia; Animals; Blood Pressure; Cats; Cocaine; Dogs; Drug Interactions; Ethanolamines; Female; Heart Rate; Labetalol; Male; Norepinephrine; Phenylephrine; Propranolol; Rats; Spinal Cord	1975
The alpha- and beta-adrenoceptor blocking activities of labetalol and its RR-SR (50:50) stereoisomers. British journal of pharmacology, 1991, Volume: 104, Issue:4 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Cerebral Cortex; Dose-Response Relationship, Drug; Heart; Heart Rate; In Vitro Techniques; Isoproterenol; Labetalol; Male; Myocardium; Phenylephrine; Prazosin; Propranolol; Rats; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Stereoisomerism	1991
Comparative effects of arotinolol, labetalol and propranolol on regional myocardial dysfunction induced by flow-limiting coronary stenosis in anesthetized dogs. Japanese journal of pharmacology, 1990, Volume: 53, Issue:3 Topics: Adrenergic beta-Antagonists; Anesthesia; Animals; Blood Pressure; Cardiomyopathies; Coronary Vessels; Dogs; Female; Heart Rate; Hemodynamics; Isoproterenol; Labetalol; Male; Myocardial Contraction; Phenylephrine; Propanolamines; Propranolol	1990
Effects of dilevalol on adrenoceptors in isolated cat arteries. Journal of pharmacobio-dynamics, 1990, Volume: 13, Issue:11 Topics: Animals; Arteries; Cats; Clonidine; Dinoprost; Electric Stimulation; Female; In Vitro Techniques; Labetalol; Male; Norepinephrine; Phenylephrine; Prazosin; Propranolol; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Vasoconstriction; Yohimbine	1990
The effect of dilevalol on cardiac autonomic neural discharge, plasma catecholamines, and myocardial beta receptor density associated with coronary occlusion. Journal of clinical pharmacology, 1990, Volume: 30, Issue:3 Topics: Adrenergic beta-Antagonists; Animals; Autonomic Nervous System; Blood Pressure; Catecholamines; Cats; Coronary Vessels; Electrophysiology; Epinephrine; Heart Rate; Isoproterenol; Labetalol; Myocardium; Neurons; Norepinephrine; Phenylephrine; Receptors, Adrenergic, beta	1990
Alpha-blockade and vasodilatation induced by nipradilol, arotinolol and labetalol in pithed rats. Japanese journal of pharmacology, 1985, Volume: 39, Issue:4 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Pressure; Clonidine; Decerebrate State; Labetalol; Male; Phenylephrine; Prazosin; Propanolamines; Rats; Rats, Inbred Strains; Vasodilation; Yohimbine	1985
Cardiac alpha-adrenoceptors: postjunctional and prejunctional. Journal of molecular and cellular cardiology, 1986, Volume: 18 Suppl 5 Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adrenergic alpha-Antagonists; Animals; Calcium; Dioxanes; Dose-Response Relationship, Drug; Female; Heart Conduction System; Heart Rate; Idazoxan; In Vitro Techniques; Labetalol; Methoxamine; Myocardial Contraction; Myocardium; Norepinephrine; Phenylephrine; Prazosin; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Stimulation, Chemical; Verapamil	1986
Actions of dilevalol on adrenoceptors. Journal of cardiovascular pharmacology, 1988, Volume: 11 Suppl 2 Topics: Adrenergic beta-Antagonists; Animals; Aorta, Thoracic; Decerebrate State; Dose-Response Relationship, Drug; Guinea Pigs; Heart Rate; In Vitro Techniques; Isoproterenol; Labetalol; Muscle, Smooth; Phenylephrine; Receptors, Adrenergic; Trachea; Vasodilator Agents	1988
Autonomic and antihypertensive activity of oral amosulalol (YM-09538), a combined alpha- and beta-adrenoceptor blocking agent in conscious rats. Japanese journal of pharmacology, 1985, Volume: 38, Issue:1 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Autonomic Nervous System; Blood Pressure; Ethanolamines; Heart Rate; Isoproterenol; Labetalol; Male; Phenylephrine; Prazosin; Propranolol; Rats; Rats, Inbred SHR; Rats, Inbred Strains	1985
Endothelial potentiation of relaxation response to beta adrenoceptor blocking agents. The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:3 Topics: 5,8,11,14-Eicosatetraynoic Acid; Adrenergic beta-Antagonists; Animals; Aorta, Thoracic; Dinoprost; Dose-Response Relationship, Drug; Drug Synergism; Endothelium; Labetalol; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Phenylephrine; Propanolamines; Propranolol; Prostaglandin Endoperoxides, Synthetic; Prostaglandins F; Pyridines; Rats; Rats, Inbred Strains; Spiro Compounds; Timolol; Vasodilation	1986
Comparison of the effects of labetalol and SCH 19927, the R1R isomer of labetalol, on the rat isolated right ventricle and aorta. Journal of autonomic pharmacology, 1985, Volume: 5, Issue:4 Topics: Animals; Aorta; Cocaine; Dioxanes; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Idazoxan; In Vitro Techniques; Isoproterenol; Labetalol; Male; Myocardial Contraction; Norepinephrine; Phenylephrine; Rats; Rats, Inbred Strains; Serotonin; Stereoisomerism; Vasoconstriction	1985
Alpha-adrenoceptor blockade by labetalol during long-term dosing. Clinical pharmacology and therapeutics, 1983, Volume: 33, Issue:3 Topics: Adrenergic alpha-Antagonists; Adult; Blood Pressure; Dose-Response Relationship, Drug; Ethanolamines; Female; Heart Rate; Humans; Hypertension; Isoproterenol; Labetalol; Male; Middle Aged; Phenylephrine	1983
Comparison of medroxalol and labetalol, drugs with combined alpha- and beta-adrenoceptor antagonist properties. British journal of clinical pharmacology, 1984, Volume: 17, Issue:5 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Blood Pressure; Depression, Chemical; Double-Blind Method; Drug Evaluation; Ethanolamines; Heart Rate; Humans; Isoproterenol; Labetalol; Male; Norepinephrine; Phenylephrine; Posture	1984
Bronchospasm and hypotension during cardiopulmonary bypass after preoperative cimetidine and labetalol therapy. British journal of anaesthesia, 1984, Volume: 56, Issue:8 Topics: Bronchial Spasm; Cardiopulmonary Bypass; Cimetidine; Drug Interactions; Humans; Hypotension; Intraoperative Complications; Labetalol; Male; Middle Aged; Phenylephrine; Premedication	1984
Response of the systemic pulmonary circulation to labetalol at rest and during exercise. British journal of clinical pharmacology, 1982, Volume: 13, Issue:1 Suppl Topics: Adult; Aldosterone; Ethanolamines; Female; Hemodynamics; Humans; Hypertension; Labetalol; Male; Phenylephrine; Physical Exertion; Pulmonary Circulation; Renin; Rest	1982
Blockade of the rate and force responses to phenylephrine on rat atria with labetalol. Research communications in chemical pathology and pharmacology, 1980, Volume: 29, Issue:2 Topics: Animals; Ethanolamines; Heart Rate; In Vitro Techniques; Labetalol; Male; Myocardial Contraction; Phenylephrine; Rats	1980
Vasoactive mediators and the progression from oedematous to necrotising experimental acute pancreatitis. Gut, 1995, Volume: 37, Issue:3 Topics: Acute Disease; Animals; Arginine; Bradykinin; Catecholamines; Ceruletide; Edema; Labetalol; Male; Microcirculation; Microscopy, Electron, Scanning; Necrosis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitroglycerin; Pancreas; Pancreatitis; Phenylephrine; Rats; Rats, Wistar	1995
Eugenodilol: a third-generation beta-adrenoceptor blocker, derived from eugenol, with alpha-adrenoceptor blocking and beta2-adrenoceptor agonist-associated vasorelaxant activities. Journal of cardiovascular pharmacology, 1999, Volume: 34, Issue:1 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Anesthesia; Animals; Aorta, Thoracic; Bradycardia; Dose-Response Relationship, Drug; Drug Interactions; Eugenol; Female; Guinea Pigs; Hypotension; In Vitro Techniques; Isoproterenol; Labetalol; Male; Muscle Contraction; Phenylephrine; Radioligand Assay; Rats; Rats, Wistar; Time Factors; Trachea; Vasodilator Agents	1999
Shy-Drager syndrome and severe unexplained intraoperative hypotension responsive to vasopressin. Anesthesia and analgesia, 2002, Volume: 95, Issue:1 Topics: Adrenergic beta-Antagonists; Aged; Hemodynamics; Humans; Hypotension; Intraoperative Complications; Labetalol; Leg Ulcer; Male; Monitoring, Intraoperative; Multiple System Atrophy; Phenylephrine; Shy-Drager Syndrome; Vasoconstrictor Agents; Vasopressins	2002