labetalol and phentolamine

labetalol has been researched along with phentolamine in 45 studies

Research

Studies (45)

Timeframe	Studies, this research(%)	All Research%
pre-1990	33 (73.33)	18.7374
1990's	3 (6.67)	18.2507
2000's	4 (8.89)	29.6817
2010's	5 (11.11)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
Brittain, RT; Levy, GP	1
Doggrell, SA; Paton, DM	1
Dobbs, RJ; Prichard, BN; Richards, DA	1
Hashimoto, K; Hashimoto, T; Iizuka, H; Imai, S; Matsuda, H; Tsukada, T	1
Agabiti-Rosei, E; Alicandri, C; Fariello, R; Muiesan, G	1
Johnson, BF; LaBrooy, J; Munro-Faure, AD	2
Maconochie, JG; Richards, DA; Woodings, EP	1
Goldberg, SR; Schindler, CW; Tella, SR	1
Aycock, BG; Hawtof, DB; Moody, SB	1
Smirnov, GB	1
Angilivilayil, C; Ibrahim, M; Lunell, NO; Moberger, B; Thulesius, O	1
Abou Hamdam, B; Bernard, R; Jacobs, P; Liebens, I; Renard, M	1
Vidt, DG	1
Holzmann, A; Loupal, G; Stackl, W	1
Kameda, H	1
Bouffioux, CR; Penders, L	1
Booth, RJ; Bullock, JY; Wilson, JD	1
Riley, AJ	1
Cheng, HC; Woodward, JK	1
Clifton, JE; Collins, I; Hallett, P; Hartley, D; Lunts, LH; Wicks, PD	1
Dukes, ID; Vaughan Williams, EM	1
Bamonte, F; Forlani, A; Monopoli, A; Ongini, E; Parravicini, L	1
Abiko, Y; Hosaka, A; Kogure, H	1
Ashbrook, DW; Purdy, RE; Stupecky, GL; Watanabe, MY	1
Ram, CV	1
Galletly, DC; Maling, TJ; Yee, P	1
Isobe, K; Iwatsuki, K; Nakai, T; Okuda, C; Sakio, H; Yamada, R	1
Bernard, R; Renard, M	1
Agabiti-Rosei, E; Alicandri, CL; Beschi, M; Boni, E; Castellano, M; Fariello, R; Montini, E; Muiesan, G; Romanelli, G; Zaninelli, A	1
Agabiti-Rosei, E; Alicandri, C; Beschi, M; Boni, E; Castellano, M; Fariello, R; Muiesan, G; Muiesan, ML; Romanelli, G	1
Kogure, H	1
Gulati, N; Gulati, OP; Huggel, H	1
Agabiti-Rosei, E; Alicandri, CL; Fariello, R; Muiesan, G; Romanelli, G	1
Bowles, R	1
Kemp, GJ; Odoom, JE; Radda, GK	1
Marik, PE; Varon, J	1
Brocher, N; Copeland, A; Godfrey, J; Thornton, H; Wilson, C	1
Bhargava, KK; Gupta, S; Ito, Y; McCuskey, RS; Palestro, CJ; Rajvanshi, P; Slehria, S; Sokhi, RP	1

Reviews

5 review(s) available for labetalol and phentolamine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
A review of the animal pharmacology of labetalol, a combined alpha- and beta-adrenoceptor-blocking drug. British journal of clinical pharmacology, 1976, Volume: 3, Issue:4 Suppl 3 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Autonomic Fibers, Preganglionic; Desoxycorticosterone; Dogs; Electric Stimulation; Ethanolamines; Guinea Pigs; Hemodynamics; Hypertension; Hypertension, Renal; In Vitro Techniques; Isoproterenol; Labetalol; Male; Muscle Contraction; Muscle, Smooth; Myocardial Contraction; Phentolamine; Phenylephrine; Propranolol; Rabbits; Rats	1976
Alpha-blockers in the treatment of benign prostatic hypertrophy: physiological basis and review of the problem. European urology, 1984, Volume: 10, Issue:5 Topics: Adrenergic alpha-Antagonists; Clinical Trials as Topic; Double-Blind Method; Humans; Labetalol; Male; Phenoxybenzamine; Phentolamine; Prazosin; Prostatic Hyperplasia; Receptors, Adrenergic, alpha	1984
Hypertensive crisis. Cardiology clinics, 1984, Volume: 2, Issue:2 Topics: Antihypertensive Agents; Brain Diseases; Cerebrovascular Disorders; Clonidine; Coronary Disease; Diazoxide; Eclampsia; Emergencies; Female; Humans; Hydralazine; Hypertension; Hypertension, Malignant; Labetalol; Minoxidil; Nifedipine; Nitroprusside; Phentolamine; Prazosin; Pregnancy; Pulmonary Edema; Trimethaphan	1984
The diagnosis and management of hypertensive crises. Chest, 2000, Volume: 118, Issue:1 Topics: Antihypertensive Agents; Aortic Aneurysm; Aortic Dissection; Clonidine; Diazoxide; Enalaprilat; Female; Fenoldopam; Humans; Hypertension; Labetalol; Nicardipine; Nifedipine; Nitroprusside; Phentolamine; Pre-Eclampsia; Pregnancy; Propanolamines; Trimethaphan	2000

Trials

7 trial(s) available for labetalol and phentolamine

Article	Year
Catecholamines and haemodynamics in fixed essential hypertension. Clinical science (London, England : 1979), 1979, Volume: 57 Suppl 5 Topics: Adult; Aged; Blood Pressure; Cardiac Output; Epinephrine; Female; Heart Rate; Humans; Hypertension; Labetalol; Male; Middle Aged; Norepinephrine; Phentolamine; Vascular Resistance	1979
Comparative anti-hypertensive effects of labetalol and the combination of oxprenolol and phentolamine. British journal of clinical pharmacology, 1976, Volume: 3, Issue:4 Suppl 3 Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Evaluation; Drug Synergism; Drug Therapy, Combination; Ethanolamines; Female; Heart Rate; Humans; Hypertension; Labetalol; Male; Middle Aged; Oxprenolol; Phentolamine	1976
The anti-hypertensive efficacy of combined alpha- and beta-adrenoreceptor blockade with phentolamine-oxprenolol or with labetalol (AH 5158). Clinical science and molecular medicine. Supplement, 1976, Volume: 3 Topics: Adult; Aged; Clinical Trials as Topic; Drug Therapy, Combination; Ethanolamines; Female; Humans; Hypertension; Labetalol; Male; Middle Aged; Oxprenolol; Phentolamine; Physical Exertion; Posture	1976
Modification of pressor responses induced by 'cold' [proceedings]. British journal of clinical pharmacology, 1977, Volume: 4, Issue:3 Topics: Adult; Blood Pressure; Cardiac Output; Cold Temperature; Heart Rate; Humans; Labetalol; Male; Phentolamine; Propranolol	1977
Alpha-blockers in the treatment of benign prostatic hypertrophy: physiological basis and review of the problem. European urology, 1984, Volume: 10, Issue:5 Topics: Adrenergic alpha-Antagonists; Clinical Trials as Topic; Double-Blind Method; Humans; Labetalol; Male; Phenoxybenzamine; Phentolamine; Prazosin; Prostatic Hyperplasia; Receptors, Adrenergic, alpha	1984
Antinuclear antibodies in patients on acebutolol. British journal of clinical pharmacology, 1980, Volume: 9, Issue:5 Topics: Adrenergic Agonists; Blood Glucose; Blood Pressure; Clinical Trials as Topic; Ethanolamines; Humans; Hydralazine; Labetalol; Male; Phentolamine; Placebos	1980
Some further evidence for partial agonist activity of labetalol. British journal of clinical pharmacology, 1980, Volume: 9, Issue:5 Topics: Adrenergic Agonists; Blood Glucose; Blood Pressure; Clinical Trials as Topic; Ethanolamines; Humans; Hydralazine; Labetalol; Male; Phentolamine; Placebos	1980

Other Studies

34 other study(ies) available for labetalol and phentolamine

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
Effect of labetalol and guanethidine on contractile responses to acetylcholine in the rat anococcygeus muscle. The Journal of pharmacy and pharmacology, 1978, Volume: 30, Issue:7 Topics: Acetylcholine; Animals; Ethanolamines; Guanethidine; Hydroxydopamines; In Vitro Techniques; Labetalol; Male; Muscle Contraction; Phentolamine; Rats	1978
Adrenoceptor blockade of the circulatory responses to intravenous isoproterenol. Clinical pharmacology and therapeutics, 1978, Volume: 24, Issue:3 Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Cardiac Output; Heart Rate; Hemodynamics; Humans; Isoproterenol; Labetalol; Male; Myocardial Contraction; Phentolamine; Propranolol; Stroke Volume; Time Factors	1978
Hypotensive and vascular effects of labetalol in the normotensive rat and dog. Japanese heart journal, 1978, Volume: 19, Issue:5 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Blood Flow Velocity; Blood Pressure; Dogs; Ethanolamines; Female; Femoral Artery; Heart Rate; Isoproterenol; Kidney; Labetalol; Male; Phentolamine; Propranolol; Rats; Regional Blood Flow; Vasomotor System	1978
Adrenoceptor mechanisms in the cardiovascular effects of cocaine in conscious squirrel monkeys. Life sciences, 1992, Volume: 51, Issue:9 Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Blood Pressure; Cocaine; Heart Rate; Labetalol; Male; Phentolamine; Prazosin; Propanolamines; Propranolol; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Saimiri; Yohimbine	1992
Treatment of peripheral ischemia secondary to lidocaine containing epinephrine. Annals of plastic surgery, 1989, Volume: 23, Issue:1 Topics: Animals; Epinephrine; Foot; Ischemia; Labetalol; Lidocaine; Models, Biological; Necrosis; Phentolamine; Rats	1989
[Effect of beta-adrenergic blockaders and their combination with an alpha-adrenergic blockader on physical exertion tolerance in patients with hypertension]. Kardiologiia, 1986, Volume: 26, Issue:3 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Blood Pressure; Drug Therapy, Combination; Heart Rate; Humans; Hypertension; Labetalol; Oxprenolol; Oxygen Consumption; Phentolamine; Physical Endurance; Physical Exertion; Pindolol; Propranolol; Time Factors	1986
The effect of labetalol on contractility of human myometrial preparations. Acta obstetricia et gynecologica Scandinavica, 1987, Volume: 66, Issue:3 Topics: Adrenergic beta-Antagonists; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Labetalol; Methylergonovine; Phentolamine; Pregnancy; Propanolamines; Receptors, Adrenergic, beta; Uterine Contraction	1987
A comparison of the effects of combined or separate alpha- and beta-blockade in the treatment of hypertension in the acute stage of myocardial infarction. International journal of cardiology, 1986, Volume: 10, Issue:2 Topics: Adult; Aged; Blood Pressure; Carbon Dioxide; Female; Heart Rate; Humans; Hypertension; Infusions, Parenteral; Labetalol; Metoprolol; Middle Aged; Myocardial Infarction; Oxygen; Phentolamine	1986
Current concepts in treatment of hypertensive emergencies. American heart journal, 1986, Volume: 111, Issue:1 Topics: Diazoxide; Drug Therapy, Combination; Emergencies; Humans; Hydralazine; Hypertension; Labetalol; Methyldopa; Nitroglycerin; Nitroprusside; Phentolamine; Reserpine; Sympathomimetics; Trimethaphan; Vasodilator Agents	1986
Intracavernous injection of vasoactive drugs in the rabbit. Urological research, 1988, Volume: 16, Issue:6 Topics: Animals; Cavernous Sinus; Injections; Labetalol; Male; Papaverine; Penile Erection; Phenoxybenzamine; Phentolamine; Piperazines; Prostaglandins E; Rabbits; Vasoconstrictor Agents; Vasodilator Agents	1988
Effects of labetalol on in vitro preparations of the trachea and lung strips and on ventilation overflow in vivo in guinea pigs. Japanese journal of pharmacology, 1987, Volume: 43, Issue:3 Topics: Acetylcholine; Aerosols; Animals; Diphenhydramine; Female; Guinea Pigs; Histamine; In Vitro Techniques; Labetalol; Lung; Male; Phentolamine; Propranolol; Respiration; Trachea	1987
beta 2-Adrenergic agonist effects of medroxalol and labetalol on rat and mouse uterine muscle. The Journal of pharmacy and pharmacology, 1982, Volume: 34, Issue:3 Topics: Adrenergic beta-Agonists; Animals; Ethanolamines; Female; In Vitro Techniques; Labetalol; Mice; Phentolamine; Potassium Chloride; Rats; Uterine Contraction	1982
Arylethanolamines derived from salicylamide with alpha- and beta-adrenoceptor blocking activities. Preparation of labetalol, its enantiomers, and related salicylamides. Journal of medicinal chemistry, 1982, Volume: 25, Issue:6 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Chemical Phenomena; Chemistry; Dogs; Ethanolamines; Labetalol; Muscle, Smooth, Vascular; Phentolamine; Propranolol; Salicylamides; Stereoisomerism; Structure-Activity Relationship	1982
Electrophysiological effects of alpha-adrenoceptor antagonists in rabbit sino-atrial node, cardiac Purkinje cells and papillary muscles. British journal of pharmacology, 1984, Volume: 83, Issue:2 Topics: Action Potentials; Adrenergic alpha-Antagonists; Animals; Ethanolamines; Female; Heart; Heart Rate; In Vitro Techniques; Labetalol; Male; Neuromuscular Depolarizing Agents; Papillary Muscles; Phentolamine; Prazosin; Purkinje Cells; Rabbits; Sinoatrial Node	1984
Effects of the R, R-isomer of labetalol, SCH 19927, in isolated tissues and in spontaneously hypertensive rats during a repeated treatment. Archives internationales de pharmacodynamie et de therapie, 1984, Volume: 272, Issue:2 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Aorta, Thoracic; Blood Pressure; Ethanolamines; Hypertension; In Vitro Techniques; Labetalol; Male; Norepinephrine; Phentolamine; Propranolol; Rats; Rats, Inbred SHR; Stereoisomerism; Time Factors	1984
Hypotensive effect of labetalol on intraocular pressure in rabbits: in relation to its alpha- and beta-adrenergic blocking action on the cardiovascular system. Archives internationales de pharmacodynamie et de therapie, 1981, Volume: 250, Issue:1 Topics: Animals; Blood Pressure; Ethanolamines; Heart Rate; Intraocular Pressure; Labetalol; Male; Phentolamine; Propranolol; Rabbits; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta	1981
Qualitative and quantitative differences between the postsynaptic alpha adrenoceptors of rabbit ear artery and thoracic aorta. The Journal of pharmacology and experimental therapeutics, 1983, Volume: 224, Issue:3 Topics: Animals; Aorta, Thoracic; Arteries; Blood Vessels; Ear, External; In Vitro Techniques; Labetalol; Male; Methoxamine; Norepinephrine; Phenoxybenzamine; Phentolamine; Rabbits; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Vasoconstriction	1983
Anaesthetic management of combined caesarean section and phaeochromocytoma removal. Anaesthesia and intensive care, 1983, Volume: 11, Issue:3 Topics: Adrenal Gland Neoplasms; Adult; Anesthesia, General; Atenolol; Cesarean Section; Female; Humans; Labetalol; Nitrous Oxide; Pancuronium; Phentolamine; Pheochromocytoma; Preanesthetic Medication; Pregnancy; Pregnancy Complications, Neoplastic	1983
[Effects of labetalol and phentolamine on plasma catecholamine concentrations in anesthetized dogs]. Masui. The Japanese journal of anesthesiology, 1983, Volume: 32, Issue:5 Topics: Anesthesia; Animals; Blood Pressure; Catecholamines; Dogs; Ethanolamines; Heart Rate; Labetalol; Phentolamine	1983
[Heart failure and acute myocardial infarct. Current treatment]. Bulletin et memoires de l'Academie royale de medecine de Belgique, 1983, Volume: 138, Issue:11 Topics: Cardiotonic Agents; Dobutamine; Heart Failure; Humans; Imidazoles; Labetalol; Myocardial Infarction; Phentolamine; Vasodilator Agents	1983
Aortic rigidity and plasma catecholamines in essential hypertensive patients. Clinical and experimental hypertension. Part A, Theory and practice, 1982, Volume: 4, Issue:7 Topics: Adult; Aged; Aorta, Thoracic; Blood Pressure; Compliance; Epinephrine; Hemodynamics; Humans; Hypertension; Labetalol; Middle Aged; Muscle, Smooth, Vascular; Norepinephrine; Phentolamine; Propranolol; Sympathetic Nervous System	1982
Adrenergic activity in systolic hypertension. Clinical and experimental hypertension. Part A, Theory and practice, 1982, Volume: 4, Issue:7 Topics: Aged; Epinephrine; Female; Hemodynamics; Humans; Hypertension; Labetalol; Male; Middle Aged; Norepinephrine; Phentolamine; Propranolol; Systole	1982
Effects of Dl- and l-propranolol, labetalol, and phentolamine on rabbit iris blood flow determined by hydrogen clearance method. [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 1982, Volume: 57, Issue:6 Topics: Animals; Blood Pressure; Blood Volume Determination; Ethanolamines; Iris; Isomerism; Labetalol; Phentolamine; Propranolol; Rabbits; Regional Blood Flow	1982
Effect of labetalol on adrenoceptors in the isolated perfused rat mesentery. Archives internationales de pharmacodynamie et de therapie, 1980, Volume: 246, Issue:2 Topics: Animals; Ethanolamines; In Vitro Techniques; Labetalol; Norepinephrine; Phentolamine; Rats; Receptors, Adrenergic; Splanchnic Circulation; Vasoconstriction	1980
Influence of the sympathetic nervous system on aortic compliance. Clinical science (London, England : 1979), 1980, Volume: 59 Suppl 6 Topics: Adult; Aged; Aorta; Compliance; Epinephrine; Humans; Hypertension; Labetalol; Middle Aged; Muscle, Smooth, Vascular; Norepinephrine; Phentolamine; Sympathetic Nervous System	1980
Cardiovascular complications of cocaine abuse. American family physician, 1993, Volume: 47, Issue:5 Topics: Cocaine; Humans; Labetalol; Phentolamine; Receptors, Adrenergic, alpha; Vasoconstriction	1993
The regulation of total creatine content in a myoblast cell line. Molecular and cellular biochemistry, 1996, May-24, Volume: 158, Issue:2 Topics: Animals; Atenolol; Bucladesine; Butoxamine; Cell Line; Clenbuterol; Creatine; Energy Metabolism; Insulin; Insulin-Like Growth Factor I; Isoproterenol; Labetalol; Methoxamine; Mice; Muscle, Skeletal; Norepinephrine; Phentolamine; Propranolol; Sodium; Triiodothyronine	1996
The effects of atropine and adrenergic antagonists on behavioral arousal in rats. The Journal of general psychology, 2000, Volume: 127, Issue:3 Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Arousal; Atropine; Drug Synergism; Labetalol; Motor Activity; Phentolamine; Propranolol; Rats; Rats, Sprague-Dawley	2000
Hepatic sinusoidal vasodilators improve transplanted cell engraftment and ameliorate microcirculatory perturbations in the liver. Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:6 Topics: Adrenergic alpha-Antagonists; Animals; Calcitonin Gene-Related Peptide; Calcium Channel Blockers; Dipeptidyl Peptidase 4; Glucagon; Hepatocytes; Labetalol; Liver; Liver Circulation; Microcirculation; Nifedipine; Nitroglycerin; Phentolamine; Rats; Rats, Inbred F344; Rats, Mutant Strains; Splanchnic Circulation; Vasodilator Agents	2002