labetalol has been researched along with methyldopa in 90 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 28 (31.11) | 18.7374 |
| 1990's | 9 (10.00) | 18.2507 |
| 2000's | 11 (12.22) | 29.6817 |
| 2010's | 36 (40.00) | 24.3611 |
| 2020's | 6 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Glen, RC; Lowe, R; Mitchell, JB | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Gifford, RW; Tarazi, RC; Wollam, GL | 1 |
| Havard, CW; Pearson, RM | 1 |
| Boakes, AJ; Prichard, BN | 1 |
| Davies, DM; Gales, GM; Rao, JG; Rawlins, MD; Routledge, PA; Sanders, GL | 2 |
| Lamming, GD; Symonds, EB | 1 |
| Catto, GR; Edward, N; Gemmell, HG; Innes, A; Smith, FW | 1 |
| Anderson, GD; Mabie, WC; Shamsa, F; Sibai, BM; Villar, MA | 1 |
| Crawford, GA; Gallery, ED; Györy, AZ; Kelly, D | 1 |
| Naden, RP; Redman, CW | 1 |
| Ariëns, EJ; Mohr, K | 1 |
| Durando, C; Gessa, M; Leidi, L; Maina, G; Margaria, E; Medaglia, M | 1 |
| Materson, BJ | 1 |
| Elghozi, JL; Meyer, P; Saad, MA | 1 |
| Breart, G; Maillard, F; Papiernik, E; Plouin, PF; Relier, JP | 2 |
| Vidt, DG | 1 |
| Blazquez, G; Gérard, J; Lardoux, H; Leperlier, E | 1 |
| Rasmussen, K | 1 |
| Murnaghan, DJ; O'Hare, JA | 1 |
| Prichard, BN; Richards, DA | 1 |
| Lund-Johansen, P | 1 |
| Wallin, JD | 1 |
| Drayer, JI; Weber, MA | 1 |
| Prichard, BN | 1 |
| Broughton Pipkin, F; Jadoul, FA; Lamming, GD; Symonds, EM | 1 |
| Langford, H; Maloy, J; Maronde, RF; Michelson, EL; Poland, M; Wallin, JD; Wilson, D; Winer, N | 1 |
| Latham, L; Lorimer, AR; McAreavey, D; McLaren, AD; Ramsey, LE; Reid, JL; Robertson, JI; Robertson, MP; Weir, RJ | 1 |
| Al-Damluji, SF; Al-Khalidi, A; Shaarbaf, H; Tawfiq, NH | 1 |
| Clifton, G; Cruz, F; O'Neill, WM; Wallin, JD | 1 |
| Broughton Pipkin, F; Lamming, GD; Symonds, EM | 1 |
| Abassi, ZA; Cuda, G; Golomb, E; Keiser, HR; Panchal, VR; Stylianou, M; Trachewsky, D | 1 |
| Connelly, JF; Zigmont, EA | 1 |
| al-Fadly, A; el-Qarmalawi, AM; Hashem, M; Morsy, AH; Obeid, A | 1 |
| Clairambault, J; Curzi-Dascalova, L; Eiselt, M; Kauffmann, F; Médigue, C; Peirano, P; Spassov, L | 1 |
| al-Qattan, F; Makhseed, M; Omu, AE | 1 |
| Braude, PR; Khalaf, Y; Midgley, DY; Nelson-Piercy, C | 1 |
| Bolte, AC; Dekker, GA; van Geijn, HP | 1 |
| Rollins, G | 1 |
| Oparil, S; Rosenthal, T | 1 |
| Dennedy, MC; Houlihan, DD; Morrison, JJ; Ravikumar, N | 1 |
| Blasi, I; Facchinetti, F; Gori, GF; Jasonni, VM; Neri, I | 1 |
| Malik, A; Shafi, NA; Silverman, DI | 1 |
| Abdel-Hady, el-S; El-Negeri, M; Fawzy, M; Helal, AS; Nezar, M; Ragab, A | 1 |
| Eskes, TK; Gabreëls, FJ; Pasker-de Jong, PC; Pellegrino, A; van Gelder, MM; Zielhuis, GA | 1 |
| Borrajo Prol, MP; Bravo López, JJ; Iglesias Forneiro, A; Santos Nores, J | 1 |
| Graham, DF; Hadlow, N; Oates, R; Tsokos, N | 1 |
| Koucký, M | 1 |
| Jabeen, F; Malik, AR; Mir, S; Molvi, SN; Rana, VS | 1 |
| Alexander, JM; Wilson, KL | 1 |
| Arulkumaran, N; Lightstone, L | 1 |
| Bateman, BT; Ecker, JL; Fischer, MA; Hernandez-Diaz, S; Huybrechts, KF; Mogun, H; Palmsten, K; Seely, EW | 1 |
| Guo, Y; Krewski, D; Mattison, D; Nerenberg, K; Walker, MC; Wen, SW; Xie, RH | 2 |
| Charlton, F; Hennessy, A; Makris, A; Xu, B | 1 |
| Firoz, T; Gordon, R; MacDonell, K; Magee, LA; Payne, BA; Vidler, M; von Dadelszen, P | 1 |
| Chattopadhyay, S; Das, A; Pahari, S | 1 |
| Gangooly, S; Jauniaux, E; Muttukrishna, S | 1 |
| Asztalos, E; Gafni, A; Ganzevoort, JW; Gruslin, A; Helewa, M; Hutton, E; Koren, G; Lee, SK; Lee, T; Logan, AG; Magee, LA; Menzies, J; Moutquin, JM; Murphy, KE; Rey, E; Ross, S; Sanchez, J; Singer, J; Thornton, JG; von Dadelszen, P; Welch, R | 2 |
| Sibai, BM | 1 |
| Bobek, G; Hennessy, A; Makris, A; Xu, B | 1 |
| August, P; Podymow, T | 1 |
| Jim, B; Reddy, S | 1 |
| Bracken, H; Easterling, T; Magee, LA; Mool, S; Mundle, S; Parvekar, S; Shochet, T; von Dadelszen, P; Winikoff, B | 1 |
| Karumanchi, SA; Lemoine, ER | 1 |
| Aboul-Enein, HY; Ali, I; ALOthman, ZA; Alsheetan, KM | 1 |
| Badr, H; Dawood, R; El-Shamy, E; Emarh, M; Gamal, A; Masood, A; Rezk, M | 1 |
| Alers, RJ; Cauffman, E; Ghossein-Doha, C; Lopes van Balen, VA; Mulder, EG; Oben, J; Schiffer, VMMM; Smits, L; Spaanderman, MEA; van Kuijk, SMJ | 1 |
| Ashworth, D; Battersby, C; Chappell, LC; Cluver, C; Green, M; Hardy, P; McManus, RJ | 1 |
| Avalos, LA; Badon, SE; Bider-Canfield, Z; Cheetham, TC; Chen, L; Dublin, S; Easterling, TR; Holt, VL; Idu, A; Nance, N; Neugebauer, RS; Reynolds, K; Shortreed, SM | 1 |
| Allegaert, K; Flint, RB; Mian, P; Schoenmakers, S; van de Vusse, D; Versmissen, J; Visser, W | 1 |
17 review(s) available for labetalol and methyldopa
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Antihypertensive drugs: clinical pharmacology and therapeutic use.
Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Clonidine; Diazoxide; Diuretics; Ganglionic Blockers; Humans; Hydralazine; Hypertension; Labetalol; Methyldopa; Minoxidil; Monoamine Oxidase Inhibitors; Nitroprusside; Potassium; Prazosin; Secologanin Tryptamine Alkaloids; Sympatholytics | 1977 |
Antihypertensive drugs in pregnancy.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Diazoxide; Diuretics; Female; Fetus; Humans; Hydralazine; Hypertension; Labetalol; Methyldopa; Nifedipine; Placenta; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Regional Blood Flow; Uterus | 1985 |
[False stereochemical tracks in pharmacotherapy].
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Drug Antagonism; Drug Combinations; Drug Synergism; Drug Therapy; Epinephrine; Humans; Kinetics; Labetalol; Methacholine Compounds; Methyldopa; Molecular Conformation; Optical Rotation; Stereoisomerism; Substrate Specificity; Terminology as Topic | 1985 |
Adverse effects of antihypertensive treatment.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Calcium Channel Blockers; Diuretics; Enzyme Inhibitors; Humans; Hypertension; Labetalol; Methyldopa; Prazosin; Quality of Life; Sympatholytics; Vasodilator Agents | 1986 |
Comparison of labetalol with other anti-hypertensive drugs.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Diuretics; Drug Therapy, Combination; Ethanolamines; Hemodynamics; Humans; Hydralazine; Hypertension; Labetalol; Methyldopa | 1982 |
Central and peripheral blockade of the sympathetic nervous system.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Pressure; Clonidine; Diuretics; Drug Therapy, Combination; Guanabenz; Humans; Hypertension; Indoramin; Labetalol; Methyldopa; Prazosin; Quinazolines; Reserpine; Sympathetic Nervous System; Sympatholytics | 1984 |
Combined alpha- and beta-receptor inhibition in the treatment of hypertension.
Topics: Administration, Oral; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthesia; Antihypertensive Agents; Asthma; Blood Pressure; Clonidine; Diuretics; Drug Therapy, Combination; Ethanolamines; Female; Heart Failure; Humans; Hydralazine; Hypertension; Hypertension, Renal; Infusions, Parenteral; Kidney Failure, Chronic; Labetalol; Methyldopa; Parasympathetic Nervous System; Pheochromocytoma; Pregnancy; Pregnancy Complications, Cardiovascular; Substance Withdrawal Syndrome; Tetanus | 1984 |
Pharmacological treatment of severe hypertension in pregnancy and the role of serotonin(2)-receptor blockers.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Diuretics; Female; Humans; Hypertension; Ketanserin; Labetalol; Methyldopa; Nitric Oxide Donors; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Receptors, Serotonin; Serotonin Antagonists | 2001 |
The effect of antihypertensive drugs on the fetus.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Female; Fetus; Humans; Hypertension; Labetalol; Methyldopa; Pregnancy; Pregnancy Complications, Cardiovascular | 2002 |
[Current perspective of treating hypertension in pregnancy].
Topics: Antihypertensive Agents; Calcium Channel Blockers; Female; Humans; Hypertension; Hypertension, Pregnancy-Induced; Labetalol; Methyldopa; Pregnancy; Pregnancy Complications, Cardiovascular | 2011 |
Hypertensive emergencies of pregnancy.
Topics: Antihypertensive Agents; Calcium Channel Blockers; Creatine; Diuretics; Emergency Medicine; Female; Fetal Monitoring; Humans; Hydralazine; Infusions, Intravenous; Labetalol; Methyldopa; Nifedipine; Nitroprusside; North America; Oliguria; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Proteinuria | 2013 |
Severe pre-eclampsia and hypertensive crises.
Topics: Administration, Intravenous; Administration, Oral; Antihypertensive Agents; Critical Care; Early Diagnosis; Eclampsia; Female; HELLP Syndrome; Humans; Hydralazine; Hypertension, Pregnancy-Induced; Labetalol; Magnesium Sulfate; Methyldopa; Nifedipine; Nitroglycerin; Pre-Eclampsia; Pregnancy; Risk Assessment; Risk Factors; Severity of Illness Index; Treatment Outcome; United Kingdom | 2013 |
Oral antihypertensive therapy for severe hypertension in pregnancy and postpartum: a systematic review.
Topics: Administration, Oral; Antihypertensive Agents; Female; Humans; Hydralazine; Hypertension, Pregnancy-Induced; Labetalol; Methyldopa; Nifedipine; Postpartum Period; Pregnancy; Pregnancy Complications, Cardiovascular; Randomized Controlled Trials as Topic; Treatment Outcome; Vasodilator Agents | 2014 |
New Evidence in the Management of Chronic Hypertension in Pregnancy.
Topics: Algorithms; Antihypertensive Agents; Blood Pressure; Chronic Disease; Female; Humans; Hypertension; Hypertension, Pregnancy-Induced; Labetalol; Methyldopa; Pre-Eclampsia; Pregnancy; Randomized Controlled Trials as Topic | 2017 |
Hypertension and Pregnancy: Management and Future Risks.
Topics: Antihypertensive Agents; Aspirin; Cardiovascular Diseases; Chronic Disease; Diuretics; Female; Humans; Hypertension; Hypertension, Pregnancy-Induced; Labetalol; Methyldopa; Nifedipine; Platelet Aggregation Inhibitors; Pre-Eclampsia; Preconception Care; Pregnancy; Pregnancy Complications, Cardiovascular; Prenatal Care; Renal Insufficiency, Chronic; Risk Factors; Vasodilator Agents | 2019 |
Pharmacokinetics of the most commonly used antihypertensive drugs throughout pregnancy methyldopa, labetalol, and nifedipine: a systematic review.
Topics: Antihypertensive Agents; Female; Humans; Hypertension; Hypertension, Pregnancy-Induced; Labetalol; Methyldopa; Nifedipine; Pregnancy; Pregnancy Complications, Cardiovascular | 2022 |
21 trial(s) available for labetalol and methyldopa
| Article | Year |
|---|---|
Labetalol, a cross-over double blind controlled trial.
Topics: Clinical Trials as Topic; Double-Blind Method; Ethanolamines; Female; Humans; Hypertension; Labetalol; Male; Methyldopa; Placebos | 1978 |
A comparative study of methyldopa and labetalol in the treatment of hypertension.
Topics: Blood Cell Count; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Ethanolamines; Female; Heart Rate; Humans; Hypertension; Labetalol; Male; Methyldopa; Middle Aged; Patient Compliance; Time Factors | 1979 |
Use of labetalol and methyldopa in pregnancy-induced hypertension.
Topics: Administration, Oral; Blood Pressure; Ethanolamines; Female; Humans; Hypertension; Injections, Intravenous; Labetalol; Methyldopa; Pregnancy; Pregnancy Complications, Cardiovascular; Time Factors | 1979 |
The short term effects of oral labetalol in patients with chronic renal disease and hypertension.
Topics: Administration, Oral; Adult; Blood Pressure; Chronic Disease; Double-Blind Method; Female; Glomerular Filtration Rate; Humans; Hypertension; Kidney Diseases; Labetalol; Male; Methyldopa; Middle Aged; Renal Circulation; Time Factors | 1992 |
A comparison of no medication versus methyldopa or labetalol in chronic hypertension during pregnancy.
Topics: Adult; Female; Humans; Hypertension; Infant Mortality; Infant, Newborn; Labetalol; Methyldopa; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Outcome; Randomized Controlled Trials as Topic | 1990 |
Comparison of antihypertensive efficacy and perinatal safety of labetalol and methyldopa in the treatment of hypertension in pregnancy: a randomized controlled trial.
Topics: Adult; Clinical Trials as Topic; Female; Fetal Death; Fetus; Hemodynamics; Humans; Hypertension; Infant, Newborn; Labetalol; Methyldopa; Pregnancy; Pregnancy Complications, Cardiovascular; Prenatal Care; Random Allocation; Respiration | 1988 |
[Maternal effects and perinatal safety of labetalol in the treatment of hypertension in pregnancy. Comparison with methyldopa in a randomized cooperative trial].
Topics: Adult; Clinical Trials as Topic; Female; Humans; Hypertension; Labetalol; Methyldopa; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Outcome; Random Allocation | 1987 |
[Randomized, comparative study on the treatment of moderate arterial hypertension during pregnancy: methyldopa, acebutolol, labetalol].
Topics: Acebutolol; Adult; Female; Heart Rate, Fetal; Humans; Hypertension; Hypoglycemia; Infant, Newborn; Labetalol; Methyldopa; Pregnancy; Pregnancy Complications, Cardiovascular; Prospective Studies; Random Allocation | 1988 |
Treatment of severe hypertension with labetalol compared with methyldopa and furosemide. Results of a long-term, double-blind, multicenter trial.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Ethanolamines; Female; Furosemide; Humans; Hypertension; Labetalol; Male; Methyldopa; Middle Aged | 1983 |
"Third drug" trial: comparative study of antihypertensive agents added to treatment when blood pressure remains uncontrolled by a beta blocker plus thiazide diuretic.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Atenolol; Bendroflumethiazide; Blood Pressure; Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hydralazine; Hypertension; Labetalol; Male; Methyldopa; Middle Aged; Minoxidil; Prazosin | 1984 |
A controlled comparison of the antihypertensive effects of labetalol and alpha-methyldopa.
Topics: Adult; Blood Pressure; Clinical Trials as Topic; Ethanolamines; Female; Heart Rate; Humans; Hypertension; Labetalol; Male; Methyldopa; Middle Aged | 1982 |
Comparison of the alpha and beta blocking drug, labetalol, and methyl dopa in the treatment of moderate and severe pregnancy-induced hypertension.
Topics: Adult; Blood Pressure; Creatinine; Ethanolamines; Female; Fetus; Humans; Hydralazine; Hypertension; Labetalol; Labor, Obstetric; Metabolic Clearance Rate; Methyldopa; Potassium; Pregnancy; Pregnancy Complications, Cardiovascular; Sodium; Uric Acid | 1980 |
Labetalol vs. methyldopa in the treatment of pregnancy-induced hypertension.
Topics: Adult; Blood Pressure; Cesarean Section; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Hypertension; Infant, Newborn; Kuwait; Labetalol; Labor, Induced; Methyldopa; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular | 1995 |
Effect of antihypertensive therapy in preeclampsia on levels of serum interleukin-4.
Topics: Adult; Antihypertensive Agents; Enzyme-Linked Immunosorbent Assay; Female; Humans; Hydralazine; Infusions, Intravenous; Interleukin-4; Labetalol; Methyldopa; Pre-Eclampsia; Pregnancy | 1996 |
Effect of L-arginine on blood pressure in pregnancy-induced hypertension: a randomized placebo-controlled trial.
Topics: Adolescent; Adult; Antihypertensive Agents; Arginine; Blood Pressure; Female; Gestational Age; Humans; Hypertension, Pregnancy-Induced; Infusions, Intravenous; Labetalol; Methyldopa; Middle Aged; Placebos; Pregnancy | 2006 |
Role of antihypertensive therapy in mild to moderate pregnancy-induced hypertension: a prospective randomized study comparing labetalol with alpha methyldopa.
Topics: Adult; Antihypertensive Agents; Cesarean Section; Female; Humans; Hypertension, Pregnancy-Induced; Incidence; Infant, Newborn; Infant, Small for Gestational Age; Labetalol; Methyldopa; Pregnancy; Premature Birth; Proteinuria; Severity of Illness Index; Treatment Outcome; Young Adult | 2012 |
Fetomaternal outcome in severe preeclamptic women undergoing emergency cesarean section under either general or spinal anesthesia.
Topics: Adolescent; Adult; Anesthesia, General; Anesthesia, Spinal; Anticonvulsants; Antihypertensive Agents; Apgar Score; Cesarean Section; Female; Fetal Mortality; Gestational Age; Humans; Infant, Newborn; Infant, Premature; Labetalol; Magnesium Sulfate; Maternal Mortality; Methyldopa; Pre-Eclampsia; Pregnancy; Premature Birth; Prospective Studies; Seizures; Severity of Illness Index; Treatment Outcome; Young Adult | 2014 |
Control of Hypertension In Pregnancy Study randomised controlled trial-are the results dependent on the choice of labetalol or methyldopa?
Topics: Adult; Antihypertensive Agents; Blood Pressure; Clinical Decision-Making; Female; Humans; Hypertension; Hypertension, Pregnancy-Induced; Infant, Low Birth Weight; Labetalol; Methyldopa; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Premature Birth; Prenatal Care; Risk Factors; Treatment Outcome | 2016 |
Do labetalol and methyldopa have different effects on pregnancy outcome? Analysis of data from the Control of Hypertension In Pregnancy Study (CHIPS) trial.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension; Hypertension, Pregnancy-Induced; Infant, Low Birth Weight; Labetalol; Methyldopa; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Outcome | 2016 |
Oral antihypertensive regimens (nifedipine retard, labetalol, and methyldopa) for management of severe hypertension in pregnancy: an open-label, randomised controlled trial.
Topics: Administration, Oral; Adult; Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension, Pregnancy-Induced; India; Infant, Newborn; Labetalol; Methyldopa; Nifedipine; Pregnancy; Pregnancy Outcome; Treatment Outcome; Young Adult | 2019 |
Methyldopa versus labetalol or no medication for treatment of mild and moderate chronic hypertension during pregnancy: a randomized clinical trial.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension; Labetalol; Methyldopa; Pregnancy; Treatment Outcome; Young Adult | 2020 |
52 other study(ies) available for labetalol and methyldopa
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Predicting phospholipidosis using machine learning.
Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Treatment of severe and resistant hypertension.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Clonidine; Diazoxide; Diet, Sodium-Restricted; Diuretics; Humans; Hydralazine; Hypertension; Injections, Intravenous; Labetalol; Methyldopa; Nitroprusside; Patient Dropouts; Trimethaphan; Vasodilator Agents | 1978 |
Labetalol in long-term treatment of hypertension.
Topics: Adrenergic Agents; Adrenergic beta-Antagonists; Adult; Aged; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation; Ethanolamines; Female; Humans; Hypertension; Labetalol; Male; Methyldopa; Middle Aged; Posture | 1976 |
HPLC of urinary catecholamines in the presence of labetalol, captopril, and alpha-methyldopa.
Topics: Adrenal Gland Neoplasms; Captopril; Catecholamines; Chromatography, High Pressure Liquid; False Positive Reactions; Humans; Labetalol; Methyldopa; Pheochromocytoma | 1990 |
[Hypertension in pregnancy: proposed monitoring and therapy].
Topics: Adrenergic beta-Antagonists; Captopril; Diuretics; Female; Follow-Up Studies; Humans; Hydralazine; Hypertension; Labetalol; Methyldopa; Prazosin; Pregnancy; Pregnancy Complications, Cardiovascular | 1985 |
Baroreflex sensitivity alteration following transient hemispheric ischaemia in rats: protective effect of alphamethyldopa and guanfacine.
Topics: Animals; Blood Pressure; Enalapril; Guanfacine; Guanidines; Heart Rate; Ischemic Attack, Transient; Labetalol; Male; Methyldopa; Nicardipine; Phenylacetates; Pressoreceptors; Rats; Rats, Inbred Strains; Reflex; Tachycardia | 1986 |
Current concepts in treatment of hypertensive emergencies.
Topics: Diazoxide; Drug Therapy, Combination; Emergencies; Humans; Hydralazine; Hypertension; Labetalol; Methyldopa; Nitroglycerin; Nitroprusside; Phentolamine; Reserpine; Sympathomimetics; Trimethaphan; Vasodilator Agents | 1986 |
Fetal haemodynamics before and after treatment of maternal hypertension in pregnancy.
Topics: Blood Flow Velocity; Female; Fetus; Hemodynamics; Humans; Hypertension; Labetalol; Maternal-Fetal Exchange; Methyldopa; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Trimester, Third; Ultrasonics | 1987 |
Failure of anti-hypertensive drugs to control blood pressure rise with isometric exercise in hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Blood Pressure; Diuretics; Drug Therapy, Combination; Female; Humans; Hypertension; Isometric Contraction; Labetalol; Male; Methyldopa; Middle Aged; Physical Exertion; Pulse; Vasodilator Agents | 1981 |
Hemodynamic effects of antihypertensive agents.
Topics: Adolescent; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Benzothiadiazines; Cardiac Output; Clonidine; Diuretics; Follow-Up Studies; Hemodynamics; Humans; Hypertension; Labetalol; Male; Methyldopa; Middle Aged; Risk; Sodium Chloride Symporter Inhibitors; Stroke Volume | 1983 |
Antihypertensives and their impact on renal function.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Captopril; Central Nervous System; Clonidine; Glomerular Filtration Rate; Humans; Kidney; Labetalol; Methyldopa; Prazosin; Renal Circulation; Vasodilator Agents | 1983 |
Renin and aldosterone concentrations in pregnant essential hypertensives - a prospective study.
Topics: Adult; Aldosterone; Female; Humans; Hypertension; Labetalol; Methyldopa; Potassium; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Maintenance; Prospective Studies; Renin; Sodium | 1983 |
Effects of labetalol and methyldopa on renal function.
Topics: Adult; Aged; Double-Blind Method; Ethanolamines; Humans; Hypertension; Inulin; Kidney; Kidney Concentrating Ability; Labetalol; Male; Methyldopa; Middle Aged; p-Aminohippuric Acid; Vascular Resistance | 1981 |
Angiotensin II maintains, but does not mediate, isoproterenol-induced cardiac hypertrophy in rats.
Topics: Actins; Angiotensin II; Animals; Base Sequence; Biphenyl Compounds; Blood Pressure; Captopril; Cardiomegaly; DNA; DNA Primers; Dose-Response Relationship, Drug; Gene Expression; Genes, fos; Heart; Hydralazine; Hydroxyproline; Imidazoles; Isoproterenol; Labetalol; Losartan; Male; Methyldopa; Molecular Sequence Data; Myocardium; Myosins; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; RNA; RNA, Messenger; Tetrazoles; Transcription, Genetic | 1994 |
Intravenous antihypertensive agents for patients unable to take oral medications.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Calcium Channel Blockers; Enalaprilat; Furosemide; Humans; Hydralazine; Hypertension; Injections, Intravenous; Labetalol; Methyldopa; Nitroglycerin; Nitroprusside; Vasodilator Agents | 1995 |
Heart rate and heart rate variability during sleep in small-for-gestational age newborns.
Topics: Basal Metabolism; Birth Weight; Female; Fetal Growth Retardation; Gestational Age; Heart Rate; Humans; Hypertension; Infant, Newborn; Infant, Small for Gestational Age; Labetalol; Male; Methyldopa; Pregnancy; Pregnancy Complications, Cardiovascular; Sleep | 1994 |
Recurrent cholestasis following ovarian hyperstimulation syndrome: case report.
Topics: Adult; Antihypertensive Agents; Cesarean Section; Cholestasis; Female; Fertilization in Vitro; Gestational Age; Humans; Labetalol; Liver Function Tests; Methyldopa; Ovarian Hyperstimulation Syndrome; Pregnancy; Pregnancy Complications; Pregnancy, Multiple; Recurrence; Twins | 1999 |
Guidelines on high blood pressure in pregnancy give new classifications of disease.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Atenolol; Contraindications; Female; Humans; Hypertension; Labetalol; Methyldopa; Practice Guidelines as Topic; Pre-Eclampsia; Pregnancy; United States | 2000 |
Anti-hypertensive therapy and the feto-placental circulation: effects on umbilical artery resistance.
Topics: Adult; Antihypertensive Agents; Dose-Response Relationship, Drug; Female; Fetus; Humans; Hydralazine; Labetalol; Magnesium Sulfate; Methyldopa; Nifedipine; Placenta; Pre-Eclampsia; Pregnancy; Regional Blood Flow; Umbilical Arteries; Vascular Resistance | 2004 |
Management of Takayasu arteritis during pregnancy.
Topics: Adult; Angiography; Antihypertensive Agents; Cesarean Section; Diagnosis, Differential; Female; Glucocorticoids; Humans; Labetalol; Lisinopril; Magnetic Resonance Imaging; Methyldopa; Pre-Eclampsia; Prednisone; Pregnancy; Pregnancy Complications, Cardiovascular; Takayasu Arteritis; Tomography, X-Ray Computed; Ultrasonography, Doppler, Duplex | 2009 |
Is expectant management of early-onset severe preeclampsia worthwhile in low-resource settings?
Topics: Adolescent; Adult; Antihypertensive Agents; Egypt; Female; Fetal Death; Fetal Monitoring; Gestational Age; Glucocorticoids; Hospitals, Teaching; Humans; Infant, Newborn; Labetalol; Length of Stay; Methyldopa; Pre-Eclampsia; Pregnancy; Pregnancy Outcome; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Prospective Studies; Risk Factors; Young Adult | 2010 |
Antihypertensive treatment during pregnancy and functional development at primary school age in a historical cohort study.
Topics: Antihypertensive Agents; Attention; Attention Deficit Disorder with Hyperactivity; Bed Rest; Child; Child Development; Child, Preschool; Female; Humans; Hypertension, Pregnancy-Induced; Intelligence; Labetalol; Methyldopa; Netherlands; Pregnancy; Prenatal Exposure Delayed Effects; Psychomotor Performance; Schools | 2010 |
[HTA-pre-eclampsia-postpartum haemolytic-uraemic syndrome: good results can be achieved].
Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Anti-Inflammatory Agents; Antihypertensive Agents; Cesarean Section; Combined Modality Therapy; Emergencies; Female; Hemolytic-Uremic Syndrome; Humans; Hypertension; Labetalol; Methyldopa; Plasmapheresis; Pre-Eclampsia; Prednisone; Pregnancy; Puerperal Disorders; Remission Induction | 2010 |
A case of hypertension with virilisation during pregnancy.
Topics: Adult; Aspirin; Brenner Tumor; Calcium; Cesarean Section; Dehydroepiandrosterone Sulfate; Dietary Supplements; Estradiol; Fatty Acids, Omega-3; Female; Humans; Hypertension, Pregnancy-Induced; Labetalol; Methyldopa; Multiple Sclerosis; Ovarian Neoplasms; Pregnancy; Pregnancy Complications, Neoplastic; Progesterone; Steroids; Testosterone; Treatment Outcome; Virilism | 2010 |
Outpatient calcium-channel blockers and the risk of postpartum haemorrhage: a cohort study.
Topics: Adolescent; Adult; Antihypertensive Agents; Calcium Channel Blockers; Cohort Studies; Female; Humans; Hypertension; Labetalol; Medicaid; Methyldopa; Postpartum Hemorrhage; Pregnancy; Propensity Score; Risk Assessment; United States; Uterine Inertia; Young Adult | 2013 |
Trends in using beta-blockers and methyldopa for hypertensive disorders during pregnancy in a Canadian population.
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Female; Humans; Hypertension; Hypertension, Pregnancy-Induced; Labetalol; Methyldopa; Pre-Eclampsia; Pregnancy; Pregnancy Complications, Cardiovascular; Saskatchewan | 2013 |
Association between labetalol use for hypertension in pregnancy and adverse infant outcomes.
Topics: Adult; Antihypertensive Agents; Female; Humans; Hypertension, Pregnancy-Induced; Infant, Newborn; Infant, Newborn, Diseases; Labetalol; Methyldopa; Pregnancy; Retrospective Studies | 2014 |
Antihypertensive drugs methyldopa, labetalol, hydralazine, and clonidine improve trophoblast interaction with endothelial cellular networks in vitro.
Topics: Antihypertensive Agents; Cells, Cultured; Clonidine; Coculture Techniques; Culture Media, Conditioned; Cytokines; Endothelium, Vascular; Female; Humans; Hydralazine; In Vitro Techniques; Labetalol; Methyldopa; Trophoblasts | 2014 |
In-vitro study of the effect of anti-hypertensive drugs on placental hormones and angiogenic proteins synthesis in pre-eclampsia.
Topics: Activins; Angiogenic Proteins; Antigens, CD; Antihypertensive Agents; Chorionic Gonadotropin; Chorionic Villi; Dose-Response Relationship, Drug; Endoglin; Enzyme-Linked Immunosorbent Assay; Female; Humans; Hydralazine; Labetalol; Methyldopa; Placenta; Placental Hormones; Pravastatin; Pre-Eclampsia; Pregnancy; Receptors, Cell Surface; Time Factors; Tissue Culture Techniques; Vascular Endothelial Growth Factor Receptor-1 | 2014 |
The benefits/risks of treatment of non-severe hypertension in pregnancy and choice of drug remain unanswered.
Topics: Antihypertensive Agents; Female; Humans; Hypertension; Labetalol; Methyldopa; Pregnancy; Risk Assessment | 2016 |
Antihypertensive methyldopa, labetalol, hydralazine, and clonidine reversed tumour necrosis factor-α inhibited endothelial nitric oxide synthase expression in endothelial-trophoblast cellular networks.
Topics: Antihypertensive Agents; Cells, Cultured; Clonidine; Coculture Techniques; Culture Media, Conditioned; Endothelial Cells; Endothelium, Vascular; Female; Humans; Hydralazine; Interleukin-1 Receptor-Like 1 Protein; Labetalol; Methyldopa; Nitric Oxide Synthase Type III; Trophoblasts; Tumor Necrosis Factor-alpha; Uterus | 2017 |
Oral regimen management of acute hypertension in pregnancy.
Topics: Antihypertensive Agents; Female; Humans; Hypertension; Labetalol; Methyldopa; Nifedipine; Pregnancy; Pregnancy Complications, Cardiovascular | 2019 |
Applications of shun shell column and nanocomposite sorbent for analysis of eleven anti-hypertensive in human plasma.
Topics: Adsorption; Antihypertensive Agents; Chromatography, High Pressure Liquid; Diltiazem; Furosemide; Humans; Hydrochlorothiazide; Irbesartan; Iron; Labetalol; Limit of Detection; Losartan; Metal Nanoparticles; Methyldopa; Nanocomposites; Polyvinyl Alcohol; Prazosin; Propranolol; Reproducibility of Results; Solid Phase Microextraction; Spironolactone; Valsartan | 2020 |
Preventing Recurrent Preeclampsia by Tailored Treatment of Nonphysiologic Hemodynamic Adjustments to Pregnancy.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Female; Hemodynamics; Humans; Labetalol; Methyldopa; Nifedipine; Pre-Eclampsia; Pregnancy; Secondary Prevention | 2021 |
Which antihypertensive treatment is better for mild to moderate hypertension in pregnancy?
Topics: Antihypertensive Agents; Female; Humans; Hypertension, Pregnancy-Induced; Labetalol; Methyldopa; Nifedipine; Pregnancy; Prenatal Care; Treatment Outcome | 2022 |
Maternal and neonatal outcomes of antihypertensive treatment in pregnancy: A retrospective cohort study.
Topics: Antihypertensive Agents; Birth Weight; Female; Humans; Hypertension, Pregnancy-Induced; Infant; Infant, Newborn; Infant, Newborn, Diseases; Labetalol; Methyldopa; Nifedipine; Pregnancy; Pregnancy Outcome; Premature Birth; Retrospective Studies | 2022 |