labetalol and furosemide

labetalol has been researched along with furosemide in 45 studies

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-19904 (8.89)18.7374
1990's5 (11.11)18.2507
2000's17 (37.78)29.6817
2010's18 (40.00)24.3611
2020's1 (2.22)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Topliss, JG; Yoshida, F1
Faller, B; Wohnsland, F1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R1
Artursson, P; Bergström, CA; Draheim, R; Holmén, AG; Wassvik, CM1
Lombardo, F; Obach, RS; Waters, NJ1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Campillo, NE; Guerra, A; Páez, JA1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Glen, RC; Lowe, R; Mitchell, JB1
Ekins, S; Williams, AJ; Xu, JJ1
Akamatsu, M1
Chen, X; Lin, X; Skolnik, S; Wang, J1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Hannelin, M; Kaukinen, S; Oikkonen, M; Toivonen, J1
Leikin, JB; Zell-Kanter, M1
Millar, JA; Morrison, N; Wilson, PD1
Angelini, A; Dario, C; Mazzucato, A; Pauletto, P; Pessina, AC; Scannapieco, G; Semplicini, A; Vescovo, G1
Langford, H; Maloy, J; Maronde, RF; Michelson, EL; Poland, M; Wallin, JD; Wilson, D; Winer, N1
Bett, N; Boyle, P; Craswell, P; Whiting, G1
Connelly, JF; Zigmont, EA1
Alagna, C; Zeisler, J1
Polonský, J; Sádecká, J1
Bogaru, A; Cachat, F; Guignard, JP; Lepori, D; Micheli, JL1
Ayazifar, M; Murphy, MA1
Hamilton, R; Lim, K; Prasad, GV; Vincent, L1
Chernin, G; Francis, M; Heeringa, SF; Soliman, NA1
Abu-El-Enein, MA; El-Ashry, SM; El-Sherbiny, DT; El-Wasseef, DR1
Cervenka, L; Chábová, VČ; Husková, Z; Kompanowska-Jezierska, E; Kopkan, L; Kramer, HJ; Kujal, P; Malý, J; Netuka, I; Opočenský, M; Rakušan, D; Sadowski, J; Schejbalová, S; Skaroupková, P; Vaněčková, I; Vaňourková, Z; Vernerová, Z; Walkowska, A1
Aboul-Enein, HY; Ali, I; ALOthman, ZA; Alsheetan, KM1

Reviews

2 review(s) available for labetalol and furosemide

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

3 trial(s) available for labetalol and furosemide

ArticleYear
Effects of deliberate hypotension induced by labetalol on renal function.
    European journal of anaesthesiology, 1991, Volume: 8, Issue:1

    Topics: Acid-Base Equilibrium; Adult; Anesthesia, Inhalation; Blood Pressure; Body Water; Creatinine; Enflurane; Female; Fluorides; Furosemide; Humans; Hypotension, Controlled; Isoflurane; Kidney; Labetalol; Male; Middle Aged; Oxygen; Renal Circulation; Sodium; Urine

1991
Oral labetalol in hypertensive urgencies.
    The American journal of emergency medicine, 1991, Volume: 9, Issue:2

    Topics: Administration, Oral; Adult; Blood Pressure; Clinical Protocols; Emergencies; Emergency Service, Hospital; Female; Furosemide; Hospitals, University; Humans; Hypertension; Illinois; Injections, Intravenous; Labetalol; Male; Middle Aged

1991
Treatment of severe hypertension with labetalol compared with methyldopa and furosemide. Results of a long-term, double-blind, multicenter trial.
    The American journal of medicine, 1983, Oct-17, Volume: 75, Issue:4A

    Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Ethanolamines; Female; Furosemide; Humans; Hypertension; Labetalol; Male; Methyldopa; Middle Aged

1983

Other Studies

40 other study(ies) available for labetalol and furosemide

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes.
    Journal of medicinal chemistry, 2001, Mar-15, Volume: 44, Issue:6

    Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water

2001
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
QSAR study on permeability of hydrophobic compounds with artificial membranes.
    Bioorganic & medicinal chemistry, 2007, Jun-01, Volume: 15, Issue:11

    Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship

2007
Molecular characteristics for solid-state limited solubility.
    Journal of medicinal chemistry, 2008, May-22, Volume: 51, Issue:10

    Topics: Chemical Phenomena; Chemistry, Physical; Molecular Structure; Multivariate Analysis; Pharmaceutical Preparations; Regression Analysis; Solubility

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Importance of physicochemical properties for the design of new pesticides.
    Journal of agricultural and food chemistry, 2011, Apr-13, Volume: 59, Issue:7

    Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic

2011
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity

2011
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Management of severe hypertension in pregnancy by a combined drug regimen including captopril: case report.
    The New Zealand medical journal, 1983, Oct-26, Volume: 96, Issue:742

    Topics: Adult; Captopril; Drug Therapy, Combination; Female; Furosemide; Humans; Hypertension, Renovascular; Labetalol; Pregnancy; Pregnancy Complications, Cardiovascular; Pregnancy Trimester, Third; Proline

1983
[Evaluation of the efficacy of various hypotensive drugs in broad-breasted white turkeys as an experimental model of arterial hypertension with high catecholamine levels].
    Bollettino della Societa italiana di biologia sperimentale, 1983, Sep-30, Volume: 59, Issue:9

    Topics: Animals; Antihypertensive Agents; Captopril; Catecholamines; Disease Models, Animal; Furosemide; Hypertension; Labetalol; Male; Oxprenolol; Rats; Turkeys; Verapamil

1983
Minoxidil and labetalol: very effective antihypertensive combination.
    The Medical journal of Australia, 1980, Mar-08, Volume: 1, Issue:5

    Topics: Adult; Drug Therapy, Combination; Ethanolamines; Female; Furosemide; Humans; Hypertension; Labetalol; Male; Middle Aged; Minoxidil; Pyrimidines

1980
Intravenous antihypertensive agents for patients unable to take oral medications.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1995, Jul-15, Volume: 52, Issue:14

    Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Calcium Channel Blockers; Enalaprilat; Furosemide; Humans; Hydralazine; Hypertension; Injections, Intravenous; Labetalol; Methyldopa; Nitroglycerin; Nitroprusside; Vasodilator Agents

1995
Incompatibility of labetalol hydrochloride and furosemide.
    American journal of hospital pharmacy, 1993, Volume: 50, Issue:12

    Topics: Drug Incompatibility; Female; Furosemide; Humans; Labetalol; Middle Aged

1993
Determination of some cardiovascular drugs in serum and urine by capillary isotachophoresis.
    Journal of chromatography. A, 1996, May-31, Volume: 735, Issue:1-2

    Topics: Adrenergic beta-Antagonists; Amiloride; Cardiovascular Agents; Electrophoresis, Capillary; Furosemide; Humans; Hydrogen-Ion Concentration; Labetalol; Metipranolol; Metoprolol; Reproducibility of Results

1996
Severe hypertension and massive proteinuria in a newborn with renal artery stenosis.
    Pediatric nephrology (Berlin, Germany), 2004, Volume: 19, Issue:5

    Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Aorta, Abdominal; Blood Pressure; Captopril; Diuretics; Female; Furosemide; Humans; Hydralazine; Hypertension, Renovascular; Infant, Newborn; Labetalol; Magnetic Resonance Imaging; Nitroprusside; Proteinuria; Radiography; Renal Artery Obstruction

2004
Permanent visual deficits secondary to the HELLP syndrome.
    Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2005, Volume: 25, Issue:2

    Topics: Adult; Blood Pressure; Brain Infarction; Drug Therapy, Combination; Eclampsia; Female; Furosemide; HELLP Syndrome; Hemianopsia; Humans; Intracranial Hemorrhages; Labetalol; Magnetic Resonance Imaging; Mannitol; Nifedipine; Occipital Lobe; Pregnancy; Retinal Hemorrhage; Visual Acuity

2005
Minimal change disease in association with fire coral (Millepora species) exposure.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2006, Volume: 47, Issue:1

    Topics: Acute Kidney Injury; Animals; Anthozoa; Barbados; Bites and Stings; Combined Modality Therapy; Diving; Edema; Female; Forearm Injuries; Furosemide; Humans; Hydralazine; Intubation, Intratracheal; Labetalol; Marine Toxins; Middle Aged; Mitral Valve Insufficiency; Nephrosis, Lipoid; Nephrotic Syndrome; Prednisone; Pulmonary Edema; Ramipril

2006
Complete remission of nephrotic syndrome in an infant with focal segmental glomerulosclerosis: is it renin-angiotensin blockade?
    Pediatric nephrology (Berlin, Germany), 2009, Volume: 24, Issue:5

    Topics: Albumins; Amlodipine; Angiotensins; Antihypertensive Agents; Captopril; Drug Resistance; Drug Therapy, Combination; Furosemide; Glomerulosclerosis, Focal Segmental; Humans; Infant; Labetalol; Male; Nephrotic Syndrome; Prednisolone; Remission Induction; Renin-Angiotensin System

2009
Simultaneous determination of labetalol and furosemide by first-derivative synchronous spectrofluorimetry.
    Journal of fluorescence, 2009, Volume: 19, Issue:5

    Topics: Ethanol; Furosemide; Hydrogen-Ion Concentration; Labetalol; Osmolar Concentration; Spectrometry, Fluorescence; Time Factors

2009
Similar renoprotection after renin-angiotensin-dependent and -independent antihypertensive therapy in 5/6-nephrectomized Ren-2 transgenic rats: are there blood pressure-independent effects?
    Clinical and experimental pharmacology & physiology, 2010, Volume: 37, Issue:12

    Topics: Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Creatinine; Diabetic Nephropathies; Diuretics; Drug Therapy, Combination; Furosemide; Hydrochlorothiazide; Hypertension; Indoles; Kidney Failure, Chronic; Labetalol; Losartan; Proteinuria; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Renin; Renin-Angiotensin System

2010
Applications of shun shell column and nanocomposite sorbent for analysis of eleven anti-hypertensive in human plasma.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2020, Jun-01, Volume: 1146

    Topics: Adsorption; Antihypertensive Agents; Chromatography, High Pressure Liquid; Diltiazem; Furosemide; Humans; Hydrochlorothiazide; Irbesartan; Iron; Labetalol; Limit of Detection; Losartan; Metal Nanoparticles; Methyldopa; Nanocomposites; Polyvinyl Alcohol; Prazosin; Propranolol; Reproducibility of Results; Solid Phase Microextraction; Spironolactone; Valsartan

2020