labetalol and alprenolol

labetalol has been researched along with alprenolol in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19906 (23.08)18.7374
1990's0 (0.00)18.2507
2000's11 (42.31)29.6817
2010's9 (34.62)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Faller, B; Wohnsland, F1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Baker, JG1
Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R1
Artursson, P; Bergström, CA; Draheim, R; Holmén, AG; Wassvik, CM1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Campillo, NE; Guerra, A; Páez, JA1
Akamatsu, M1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U1
Bellman, K; Knegtel, RM; Settimo, L1
Aggerbeck, M; Guellaen, G; Hanoune, J1
Chimura, T1
Fishbein, L; Jackson, CD1
Dean, S; Jack, DB; Kendall, MJ; Laugher, S1
Bengtsson, C1
Hvidt, S; Kjaer, K; Kofod, P; Vejlø, S1
Ikonen, M; Kontturi, K; Murtomäki, L1
Bao, J; Johnson, PE; Krylov, SN; Krylova, SM; Reinstein, O; Wilson, DJ1
Andresen, BT; Chang, A; Chen, S; Cleveland, KH; Guo, L; Huang, KM; Huang, Y; Liang, S1

Reviews

1 review(s) available for labetalol and alprenolol

ArticleYear
A toxicological review of beta-adrenergic blockers.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1986, Volume: 6, Issue:3

    Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Atenolol; Cocarcinogenesis; Ethanolamines; Female; Kinetics; Labetalol; Lethal Dose 50; Male; Metoprolol; Mice; Mutagens; Nadolol; Neoplasms, Experimental; Oxprenolol; Pindolol; Practolol; Propanolamines; Propranolol; Rats; Sotalol; Timolol

1986

Trials

1 trial(s) available for labetalol and alprenolol

ArticleYear
Labetalol and alprenolol. A comparative investigation of antihypertensive effect.
    Postgraduate medical journal, 1980, Volume: 56 Suppl 2

    Topics: Adult; Aged; Alprenolol; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Ethanolamines; Female; Heart Rate; Humans; Hypertension; Labetalol; Male; Middle Aged

1980

Other Studies

24 other study(ies) available for labetalol and alprenolol

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes.
    Journal of medicinal chemistry, 2001, Mar-15, Volume: 44, Issue:6

    Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water

2001
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
The selectivity of beta-adrenoceptor antagonists at the human beta1, beta2 and beta3 adrenoceptors.
    British journal of pharmacology, 2005, Volume: 144, Issue:3

    Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Algorithms; Animals; Cell Line; CHO Cells; Cricetinae; Dioxoles; Humans; Propanolamines; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Receptors, Adrenergic, beta-3

2005
QSAR study on permeability of hydrophobic compounds with artificial membranes.
    Bioorganic & medicinal chemistry, 2007, Jun-01, Volume: 15, Issue:11

    Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship

2007
Molecular characteristics for solid-state limited solubility.
    Journal of medicinal chemistry, 2008, May-22, Volume: 51, Issue:10

    Topics: Chemical Phenomena; Chemistry, Physical; Molecular Structure; Multivariate Analysis; Pharmaceutical Preparations; Regression Analysis; Solubility

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Importance of physicochemical properties for the design of new pesticides.
    Journal of agricultural and food chemistry, 2011, Apr-13, Volume: 59, Issue:7

    Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic

2011
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:1

    Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests

2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Biochemical evidence for the dual action of labetalol on alpha- and beta-adrenoceptors.
    British journal of pharmacology, 1978, Volume: 62, Issue:4

    Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Alprenolol; Animals; Cell Membrane; Dihydroergotoxine; Epinephrine; Ethanolamines; Female; In Vitro Techniques; Labetalol; Liver; Myocardium; Rats; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta

1978
[Effects of beta-adrenoceptor blockade on parturition and fetal cardiovascular and metabolic system].
    Nihon Sanka Fujinka Gakkai zasshi, 1985, Volume: 37, Issue:5

    Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Blood Glucose; Ethanolamines; Female; Fetal Death; Fetal Heart; Fetus; Labetalol; Labor, Obstetric; Maternal-Fetal Exchange; Pregnancy; Rats; Rats, Inbred Strains; Regional Blood Flow; Uterine Contraction; Uterus

1985
Detection of some antihypertensive drugs and their metabolites in urine by thin-layer chromatography: II. A further five beta blockers and dihydralazine.
    Journal of chromatography, 1980, Aug-01, Volume: 196, Issue:1

    Topics: Adrenergic beta-Antagonists; Alprenolol; Atenolol; Chromatography, Thin Layer; Dihydralazine; Humans; Hypertension; Labetalol; Sotalol

1980
Impairment of physical performance after treatment with beta blockers and alpha blockers.
    British medical journal (Clinical research ed.), 1984, Mar-03, Volume: 288, Issue:6418

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Alprenolol; Heart Rate; Humans; Hydrochlorothiazide; Labetalol; Male; Metoprolol; Physical Exertion; Pindolol; Prazosin; Propranolol; Running

1984
Microcalorimetric and zeta potential study on binding of drugs on liposomes.
    Colloids and surfaces. B, Biointerfaces, 2010, Jul-01, Volume: 78, Issue:2

    Topics: Algorithms; Alprenolol; Binding Sites; Binding, Competitive; Calorimetry; Entropy; Kinetics; Labetalol; Liposomes; Models, Chemical; Molecular Structure; Pharmaceutical Preparations; Phosphatidylcholines; Phosphatidylglycerols; Propranolol; Tetracaine; Thermodynamics

2010
Kinetic capillary electrophoresis with mass-spectrometry detection (KCE-MS) facilitates label-free solution-based kinetic analysis of protein-small molecule binding.
    Chembiochem : a European journal of chemical biology, 2011, Nov-25, Volume: 12, Issue:17

    Topics: Alprenolol; Electrophoresis, Capillary; Kinetics; Labetalol; Mass Spectrometry; Orosomucoid; Pindolol; Propranolol; Protein Binding; Proteins; Small Molecule Libraries

2011
Carvedilol inhibits EGF-mediated JB6 P+ colony formation through a mechanism independent of adrenoceptors.
    PloS one, 2019, Volume: 14, Issue:5

    Topics: Adrenergic beta-Antagonists; Alprenolol; Animals; Carvedilol; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Epidermal Growth Factor; Inhibitory Concentration 50; Labetalol; Ligands; Mice; Mice, Inbred C57BL; Receptors, Adrenergic; Receptors, Adrenergic, beta; RNA, Small Interfering; Signal Transduction; Skin; Skin Neoplasms; Ultraviolet Rays

2019