labetalol has been researched along with acebutolol in 39 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (30.77) | 18.7374 |
| 1990's | 3 (7.69) | 18.2507 |
| 2000's | 13 (33.33) | 29.6817 |
| 2010's | 9 (23.08) | 24.3611 |
| 2020's | 2 (5.13) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P | 1 |
| Baker, JG | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Akamatsu, M | 1 |
| Chen, X; Lin, X; Skolnik, S; Wang, J | 1 |
| Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Wilcox, RG | 1 |
| Amlie, JP | 1 |
| Leloux, MS; Niessen, WM; van der Hoeven, RA | 1 |
| Abrignani, MG; Corda, M; Cosentino, F; Liquori, M; Novo, S; Pinto, A; Strano, A | 1 |
| Palkama, A; Raij, K; Uusitalo, H; Uusitalo, R | 1 |
| Fishbein, L; Jackson, CD | 1 |
| Duchene-Marullaz, P; Kantelip, JP; Wurm, M | 1 |
| Blazquez, G; Gérard, J; Lardoux, H; Leperlier, E | 1 |
| de V Joubert, JJ; Luus, HG; Roelofse, JA; Shipton, EA | 1 |
| Grotepass, FW; Joubert, JJ; Roelofse, JA; Shipton, EA | 1 |
| Hurwitz, MD; Kallenbach, JM; Pincus, PS | 1 |
| Baldwin, CJ; Gribbin, HR; Mackay, AD; Tattersfield, AE | 1 |
| Germond, C; Kallenbach, J; Lewis, M; Muller, F; Steyn, J; Zaltzman, M; Zwi, S | 1 |
| Corvol, P; Lardoux, MD; Thibonnier, M | 1 |
| Castiglioni, P; di Rienzo, M; Frattola, A; Mancia, G; Mutti, E; Parati, G | 1 |
| Enlow, B; Howell, JM; Klein-Schwartz, W; Litovitz, TL; Love, JN | 1 |
| Arima, Y; Hasegawa, C; Izawa, H; Kumazawa, T; Lee, XP; Sato, K; Umezawa, H | 1 |
| Ansorge, M; Dovhunová, M; Galić, N; Habinovec, I; Pocrnić, M; Tesařová, E | 1 |
| Carlo, MJ; Patrick, AL | 1 |
2 review(s) available for labetalol and acebutolol
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
A toxicological review of beta-adrenergic blockers.
Topics: Acebutolol; Adrenergic beta-Antagonists; Alprenolol; Animals; Atenolol; Cocarcinogenesis; Ethanolamines; Female; Kinetics; Labetalol; Lethal Dose 50; Male; Metoprolol; Mice; Mutagens; Nadolol; Neoplasms, Experimental; Oxprenolol; Pindolol; Practolol; Propanolamines; Propranolol; Rats; Sotalol; Timolol | 1986 |
5 trial(s) available for labetalol and acebutolol
| Article | Year |
|---|---|
Randomised study of six beta-blockers and a thiazide diuretic in essential hypertension.
Topics: Acebutolol; Adrenergic beta-Antagonists; Adult; Atenolol; Bendroflumethiazide; Clinical Trials as Topic; Female; Humans; Hypertension; Labetalol; Male; Middle Aged; Pindolol; Propranolol; Random Allocation; Timolol | 1978 |
Regression of structural vascular changes after chronic treatment in hypertensives.
Topics: Acebutolol; Adult; Aged; Blood Pressure; Captopril; Female; Hemodynamics; Humans; Hypertension; Labetalol; Leg; Male; Metoprolol; Middle Aged; Regional Blood Flow; Vascular Resistance | 1991 |
Comparative effects of acebutolol and labetalol on peripheral hemodynamics in healthy volunteers.
Topics: Acebutolol; Adolescent; Adult; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Heart Rate; Hemodynamics; Humans; Labetalol; Leg; Male; Random Allocation; Regional Blood Flow; Vascular Resistance | 1988 |
[Randomized, comparative study on the treatment of moderate arterial hypertension during pregnancy: methyldopa, acebutolol, labetalol].
Topics: Acebutolol; Adult; Female; Heart Rate, Fetal; Humans; Hypertension; Hypoglycemia; Infant, Newborn; Labetalol; Methyldopa; Pregnancy; Pregnancy Complications, Cardiovascular; Prospective Studies; Random Allocation | 1988 |
Comparative trial of labetalol and acebutolol, alone or associated with dihydralazine, in treatment of essential hypertension.
Topics: Acebutolol; Adult; Clinical Trials as Topic; Dihydralazine; Drug Therapy, Combination; Ethanolamines; Female; Humans; Hydralazine; Hypertension; Labetalol; Male; Middle Aged; Renin | 1980 |
32 other study(ies) available for labetalol and acebutolol
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties | 2004 |
The selectivity of beta-adrenoceptor antagonists at the human beta1, beta2 and beta3 adrenoceptors.
Topics: Adrenergic beta-1 Receptor Agonists; Adrenergic beta-2 Receptor Agonists; Adrenergic beta-3 Receptor Agonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Algorithms; Animals; Cell Line; CHO Cells; Cricetinae; Dioxoles; Humans; Propanolamines; Receptors, Adrenergic, beta-1; Receptors, Adrenergic, beta-2; Receptors, Adrenergic, beta-3 | 2005 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
QSAR study on permeability of hydrophobic compounds with artificial membranes.
Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Importance of physicochemical properties for the design of new pesticides.
Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic | 2011 |
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity | 2011 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
A study of the labetalol-induced changes in conductivity and refractoriness of the dog heart in situ.
Topics: Acebutolol; Animals; Atrioventricular Node; Dogs; Electrocardiography; Ethanolamines; Heart Conduction System; Heart Rate; Labetalol | 1978 |
Thermospray liquid chromatography/mass spectrometry of polar beta-blocking drugs: preliminary results.
Topics: Acebutolol; Adrenergic beta-Antagonists; Atenolol; Gas Chromatography-Mass Spectrometry; Humans; In Vitro Techniques; Labetalol; Sotalol | 1991 |
Comparison of the effects of adrenergic agonists and alpha-, beta 1-, beta 2-antagonists on the intraocular pressure and adenylate cyclase activity in the ciliary processes of the rabbit.
Topics: Acebutolol; Adenylyl Cyclases; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Ciliary Body; Intraocular Pressure; Isoproterenol; Labetalol; Metoprolol; Rats; Timolol; Water | 1985 |
The cardiovascular response to tracheal intubation during anaesthesia for oral surgical procedures. Effects of labetalol, acebutolol and lignocaine on cardiac rhythm.
Topics: Acebutolol; Adult; Anesthesia, Dental; Anesthesia, Intravenous; Arrhythmias, Cardiac; Female; Heart Rate; Humans; Intubation, Intratracheal; Labetalol; Lidocaine; Male | 1986 |
A comparison of labetalol, acebutolol, and lidocaine for controlling the cardiovascular responses to endotracheal intubation for oral surgical procedures.
Topics: Acebutolol; Adult; Anesthesia, Dental; Anesthesia, General; Blood Pressure; Female; Hemodynamics; Humans; Intubation, Intratracheal; Labetalol; Laryngoscopy; Lidocaine; Male; Mouth; Preanesthetic Medication; Pulse | 1987 |
Massive propranolol overdose.
Topics: Acebutolol; Adult; Dose-Response Relationship, Drug; Female; Humans; Isoproterenol; Labetalol; Suicide, Attempted | 1986 |
Bronchial and cardiac beta-adrenoceptor blockade--a comparison of atenolol, acebutolol and labetalol.
Topics: Acebutolol; Airway Resistance; Atenolol; Bronchi; Dose-Response Relationship, Drug; Ethanolamines; Heart; Heart Rate; Humans; Labetalol; Physical Exertion; Propanolamines; Receptors, Adrenergic; Receptors, Adrenergic, beta | 1981 |
Survival following massive overdose of adrenergic blocking agents (acebutolol and labetalol).
Topics: Acebutolol; Adult; Atropine; Blood Pressure; Dopamine; Ethanolamines; Female; Heart Rate; Hemodynamics; Humans; Isoproterenol; Labetalol; Suicide, Attempted; Trimipramine | 1983 |
Beta-adrenergic blocking treatment and 24-hour baroreflex sensitivity in essential hypertensive patients.
Topics: Acebutolol; Adrenergic beta-Antagonists; Adult; Baroreflex; Blood Pressure; Circadian Rhythm; Female; Humans; Hypertension; Labetalol; Male; Middle Aged; Pulse | 1994 |
Electrocardiographic changes associated with beta-blocker toxicity.
Topics: Acebutolol; Adolescent; Adrenergic beta-Antagonists; Adult; Blood Pressure; Electrocardiography; Female; Heart Rate; Humans; Labetalol; Male; Middle Aged; Poison Control Centers; Propranolol; Prospective Studies | 2002 |
Simultaneous determination of beta-blockers in human plasma using liquid chromatography-tandem mass spectrometry.
Topics: Acebutolol; Adrenergic beta-Antagonists; Chromatography, Liquid; Humans; Labetalol; Linear Models; Metoprolol; Pindolol; Propranolol; Sensitivity and Specificity; Tandem Mass Spectrometry | 2008 |
Chiral separation of beta-blockers by high-performance liquid chromatography and determination of bisoprolol enantiomers in surface waters.
Topics: Acebutolol; Adrenergic beta-Antagonists; Atenolol; Bisoprolol; Chromatography, High Pressure Liquid; Labetalol; Metoprolol; Water | 2020 |
Further exploration of the collision-induced dissociation of select beta blockers: Acebutolol, atenolol, bisoprolol, carteolol, and labetalol.
Topics: Acebutolol; Atenolol; Bisoprolol; Carteolol; Chromatography, Liquid; Labetalol; Tandem Mass Spectrometry | 2023 |