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l-pyroglutamyl-l-histidyl-3,3-dimethylprolinamide and methysergide

l-pyroglutamyl-l-histidyl-3,3-dimethylprolinamide has been researched along with methysergide in 2 studies

Compound Research Comparison

Studies
(l-pyroglutamyl-l-histidyl-3,3-dimethylprolinamide)
Trials
(l-pyroglutamyl-l-histidyl-3,3-dimethylprolinamide)
Recent Studies (post-2010)
(l-pyroglutamyl-l-histidyl-3,3-dimethylprolinamide)
Studies
(methysergide)
Trials
(methysergide)
Recent Studies (post-2010) (methysergide)
138722,9358180

Protein Interaction Comparison

ProteinTaxonomyl-pyroglutamyl-l-histidyl-3,3-dimethylprolinamide (IC50)methysergide (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.0021
Alpha-2A adrenergic receptorHomo sapiens (human)1.631
D(2) dopamine receptorHomo sapiens (human)0.807
Alpha-2B adrenergic receptorHomo sapiens (human)4.763
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.054
D(1A) dopamine receptorHomo sapiens (human)0.943
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.013
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.0021
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)0.054
D(3) dopamine receptorHomo sapiens (human)0.172
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.0006
5-hydroxytryptamine receptor 6Homo sapiens (human)0.162

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Clarke, KA; Parker, AJ; Stirk, GC1
Chi, J; Rogers, RC; Stephens, RL; Varanasi, S1

Other Studies

2 other study(ies) available for l-pyroglutamyl-l-histidyl-3,3-dimethylprolinamide and methysergide

ArticleYear
Potentiation of motoneurone excitability by combined administration of 5-HT agonist and TRH analogue.
    Neuropeptides, 1985, Volume: 6, Issue:3

    Topics: Animals; Anterior Horn Cells; Drug Synergism; Female; Fenclonine; Ketanserin; Methoxydimethyltryptamines; Methysergide; Motor Neurons; Piperidines; Pyrrolidonecarboxylic Acid; Rats; Serotonin; Stimulation, Chemical; Thyrotropin-Releasing Hormone

1985
Methiothepin but not methysergide antagonizes TRH effects at the dorsal vagal complex.
    Annals of the New York Academy of Sciences, 1998, Dec-15, Volume: 861

    Topics: Animals; Methiothepin; Methysergide; Neurons; Pyrrolidonecarboxylic Acid; Rats; Receptors, Serotonin; Thyrotropin-Releasing Hormone; Vagus Nerve

1998