Page last updated: 2024-09-02

l-pyroglutamyl-l-histidyl-3,3-dimethylprolinamide and capsaicin

l-pyroglutamyl-l-histidyl-3,3-dimethylprolinamide has been researched along with capsaicin in 7 studies

Compound Research Comparison

Studies
(l-pyroglutamyl-l-histidyl-3,3-dimethylprolinamide)
Trials
(l-pyroglutamyl-l-histidyl-3,3-dimethylprolinamide)
Recent Studies (post-2010)
(l-pyroglutamyl-l-histidyl-3,3-dimethylprolinamide)
Studies
(capsaicin)
Trials
(capsaicin)
Recent Studies (post-2010) (capsaicin)
1387211,2386613,410

Protein Interaction Comparison

ProteinTaxonomyl-pyroglutamyl-l-histidyl-3,3-dimethylprolinamide (IC50)capsaicin (IC50)
Transient receptor potential cation channel subfamily V member 1Rattus norvegicus (Norway rat)0.019
Lysine-specific histone demethylase 1AHomo sapiens (human)0.6
Bile salt export pumpHomo sapiens (human)10
Cytochrome P450 1A2Homo sapiens (human)3
Prostaglandin G/H synthase 1Homo sapiens (human)2.6755
Transient receptor potential cation channel subfamily V member 1Homo sapiens (human)0.008

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (71.43)18.2507
2000's2 (28.57)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Guth, PH; Kiràly, A; Livingston, EH; St Pierre, S; Sütö, G; Taché, Y1
Kaneko, H; Kato, K; Király, A; Sütö, G; Taché, Y; Yoneda, M1
Kato, K; Taché, Y; Yang, H1
Guth, PH; Király, A; Sütó, G; Taché, Y2
Kurosawa, M; Terano, A; Watanobe, H; Yoneda, M1
Kono, T; Nakamura, K; Sato, Y; Terano, A; Watanobe, H; Yokohama, S; Yoneda, M1

Other Studies

7 other study(ies) available for l-pyroglutamyl-l-histidyl-3,3-dimethylprolinamide and capsaicin

ArticleYear
Central vagal activation by TRH induces gastric hyperemia: role of CGRP in capsaicin-sensitive afferents in rats.
    The American journal of physiology, 1994, Volume: 267, Issue:6 Pt 1

    Topics: Animals; Bethanechol; Biphenyl Compounds; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Capsaicin; Gastric Mucosa; Hyperemia; Male; Peptide Fragments; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Thyrotropin-Releasing Hormone; Vagus Nerve

1994
Intracisternal thyrotropin-releasing hormone-induced vagally mediated gastric protection against ethanol lesions: central and peripheral mechanisms.
    Journal of gastroenterology and hepatology, 1994, Volume: 9 Suppl 1

    Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Dinoprostone; Ethanol; Gastric Acid; Gastric Mucosa; Injections, Intraventricular; Neurons, Afferent; Nitric Oxide; Pyrrolidonecarboxylic Acid; Rats; Stomach; Stomach Ulcer; Thyrotropin-Releasing Hormone; Vagus Nerve

1994
Role of peripheral capsaicin-sensitive neurons and CGRP in central vagally mediated gastroprotective effect of TRH.
    The American journal of physiology, 1994, Volume: 266, Issue:5 Pt 2

    Topics: Animals; Antibodies, Monoclonal; Calcitonin Gene-Related Peptide; Capsaicin; Ethanol; Gastric Mucosa; Male; Motor Neurons; Neurons; Peptide Fragments; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Thyrotropin-Releasing Hormone; Vagus Nerve

1994
Mechanisms mediating gastric hyperemic and acid responses to central TRH analog at a cytoprotective dose.
    The American journal of physiology, 1997, Volume: 273, Issue:1 Pt 1

    Topics: Animals; Blood Pressure; Calcitonin Gene-Related Peptide; Capsaicin; Gastric Acid; Gastric Mucosa; Hemodynamics; Hyperemia; Indomethacin; Male; Peptide Fragments; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Reference Values; Thyrotropin-Releasing Hormone; Time Factors; Vascular Resistance

1997
Peripheral mediators involved in gastric hyperemia to vagal activation by central TRH analog in rats.
    The American journal of physiology, 1998, Volume: 274, Issue:1

    Topics: Animals; Arginine; Atropine; Blood Pressure; Capsaicin; Cisterna Magna; Electric Stimulation; Gastric Acid; Gastric Mucosa; Hyperemia; Male; NG-Nitroarginine Methyl Ester; Pyrrolidonecarboxylic Acid; Rats; Rats, Sprague-Dawley; Stereoisomerism; Stereotaxic Techniques; Thyrotropin-Releasing Hormone; Vagus Nerve; Vascular Resistance

1998
Lafutidine increases hepatic blood flow via potentiating the action of central thyrotropin-releasing hormone in rats.
    Journal of gastroenterology and hepatology, 2003, Volume: 18, Issue:2

    Topics: Acetamides; Analysis of Variance; Animals; Capsaicin; Drug Combinations; Drug Synergism; Gastric Mucosa; Histamine H2 Antagonists; Laser-Doppler Flowmetry; Liver; Liver Circulation; Male; Neurons, Afferent; Piperidines; Pyridines; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; Receptors, Calcitonin Gene-Related Peptide; Thyrotropin-Releasing Hormone

2003
Involvement of calcitonin gene-related peptide and capsaicin-sensitive afferents in central thyrotropin-releasing hormone-induced hepatic cytoprotection.
    European journal of pharmacology, 2003, Oct-08, Volume: 478, Issue:2-3

    Topics: Animals; Aspartate Aminotransferases; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Capsaicin; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cisterna Magna; Injections; Liver; Liver Function Tests; Male; Neurons, Afferent; Peptide Fragments; Pyrrolidonecarboxylic Acid; Rats; Rats, Wistar; Thyrotropin-Releasing Hormone

2003