l 767679 has been researched along with beta-alanine in 4 studies
*beta-Alanine: An amino acid formed in vivo by the degradation of dihydrouracil and carnosine. Since neuronal uptake and neuronal receptor sensitivity to beta-alanine have been demonstrated, the compound may be a false transmitter replacing GAMMA-AMINOBUTYRIC ACID. A rare genetic disorder, hyper-beta-alaninemia, has been reported. [MeSH]
*beta-Alanine: An amino acid formed in vivo by the degradation of dihydrouracil and carnosine. Since neuronal uptake and neuronal receptor sensitivity to beta-alanine have been demonstrated, the compound may be a false transmitter replacing GAMMA-AMINOBUTYRIC ACID. A rare genetic disorder, hyper-beta-alaninemia, has been reported. [MeSH]
| Studies (l 767679) | Trials (l 767679) | Recent Studies (post-2010) (l 767679) | Studies (beta-alanine) | Trials (beta-alanine) | Recent Studies (post-2010) (beta-alanine) |
|---|---|---|---|---|---|
| 7 | 0 | 0 | 3,177 | 207 | 1,807 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baillie, TA; Breslin, MJ; Gorham, LM; Hartman, GD; Hutchinson, JH; Prueksaritanont, T; Vyas, KP | 1 |
| Gorham, LM; Prueksaritanont, T; Yeh, KC | 1 |
| Cohn, D; DeLuna, P; Gorham, LM; Leung, K; Lin, JH; Ma, B; Pang, J; Prueksaritanont, T; Xu, X | 1 |
| Bednar, B; Bednar, RA; Cook, JJ; Cunningham, ME; Gould, RJ; Hartman, GD; Holahan, MA; Jumes, PA | 1 |
4 other study(ies) available for l 767679 and beta-alanine
| Article | Year |
|---|---|
In vitro and in vivo evaluations of the metabolism, pharmacokinetics, and bioavailability of ester prodrugs of L-767,679, a potent fibrinogen receptor antagonist: an approach for the selection of a prodrug candidate.
Topics: Administration, Oral; Animals; beta-Alanine; Biological Availability; Chromatography, High Pressure Liquid; Dogs; Humans; Macaca mulatta; Male; Microsomes, Liver; Piperazines; Platelet Glycoprotein GPIIb-IIIa Complex; Prodrugs; Species Specificity | 1997 |
Analysis of metabolite kinetics by deconvolution and in vivo-in vitro correlations of metabolite formation rates: studies of fibrinogen receptor antagonist ester prodrugs.
Topics: Animals; beta-Alanine; Dogs; Esters; Macaca mulatta; Male; Microsomes, Liver; Piperazines; Platelet Glycoprotein GPIIb-IIIa Complex; Prodrugs | 1997 |
In vitro and in vivo evaluations of intestinal barriers for the zwitterion L-767,679 and its carboxyl ester prodrug L-775,318. Roles of efflux and metabolism.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; beta-Alanine; Caco-2 Cells; Humans; Intestinal Mucosa; Male; Piperazines; Platelet Glycoprotein GPIIb-IIIa Complex; Prodrugs; Quinidine; Rats; Rats, Sprague-Dawley; Verapamil | 1998 |
Fibrinogen receptor antagonist-induced thrombocytopenia in chimpanzee and rhesus monkey associated with preexisting drug-dependent antibodies to platelet glycoprotein IIb/IIIa.
Topics: Animals; Autoantibodies; Autoimmune Diseases; Azepines; beta-Alanine; Blood Platelets; Disease Susceptibility; Dogs; Epitopes; Female; Fibrinolytic Agents; Humans; Immunoglobulin G; Macaca mulatta; Macromolecular Substances; Male; Molecular Structure; Oligopeptides; Pan troglodytes; Piperazines; Piperidines; Platelet Glycoprotein GPIIb-IIIa Complex; Primates; Protein Binding; Sulfonamides; Thrombocytopenia | 1999 |