Page last updated: 2024-09-05

l 753037 and endothelin-1

l 753037 has been researched along with endothelin-1 in 8 studies

Compound Research Comparison

Studies
(l 753037)
Trials
(l 753037)
Recent Studies (post-2010)
(l 753037)
Studies
(endothelin-1)
Trials
(endothelin-1)
Recent Studies (post-2010) (endothelin-1)
181112,7406323,394

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (25.00)18.2507
2000's5 (62.50)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Clayton, F; Fukuroda, T; Gabel, R; Hara, K; Hayama, T; Ishikawa, K; Kamei, T; Kanoh, T; Kivlighn, S; Krause, S; Lynch, J; Nishikibe, M; Noguchi, K; Nolan, N; O'Brien, J; Ohta, H; Okada, M; Ozaki, S; Pettibone, D; Saito, M; Siegl, P; William, D; Zingaro, G1
Ikeda, T; Kawai, N; Kobayashi, T; Maeda, S; Miyauchi, T; Nakao, R; Nishikibe, M; Ohta, H; Okada, M; Siegl, PK1
Ikeda, T; Kawai, N; Kobayashi, T; Miyauchi, T; Nakao, R; Nishikibe, M; Ohta, H; Okada, M; Siegl, PK1
Abraham, WT; Lamba, S; Suresh, DP1
Hanada, K; Miyauchi, T; Nakao, M; Nakao, R; Nishikibe, M; Ohta, H; Suzuki, J; Tadano, K; Uehara, S1
Kamata, K; Kanie, N; Kobayashi, T; Matsumoto, T1
Gebb, SA; Homma, N; Karoor, V; McMurtry, IF; Morio, Y; Nagaoka, T; Oka, M; Ota, H1
Kimura, K; Kitada, K; Koyama, M; Matsumura, Y; Mori, T; Ohkita, M; Suzuki, R; Tanaka, R; Yui, N1

Reviews

1 review(s) available for l 753037 and endothelin-1

ArticleYear
New developments in heart failure: role of endothelin and the use of endothelin receptor antagonists.
    Journal of cardiac failure, 2000, Volume: 6, Issue:4

    Topics: Bosentan; Carboxylic Acids; Chronic Disease; Endothelin Receptor Antagonists; Endothelin-1; Heart Failure; Humans; Indans; Peptides, Cyclic; Prognosis; Pyridines; Pyrimidines; Receptors, Endothelin; Sulfonamides; Treatment Outcome

2000

Other Studies

7 other study(ies) available for l 753037 and endothelin-1

ArticleYear
Pharmacological properties of J-104132 (L-753,037), a potent, orally active, mixed ETA/ETB endothelin receptor antagonist.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 289, Issue:3

    Topics: Animals; Binding, Competitive; Blood Pressure; CHO Cells; Cloning, Molecular; Cricetinae; Dogs; Endothelin Receptor Antagonists; Endothelin-1; Female; Hippocampus; Humans; Iliac Artery; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Muscle Contraction; Muscle, Smooth, Vascular; Phosphatidylinositols; Pulmonary Artery; Pyridines; Rabbits; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Endothelin; Recombinant Proteins; Renal Artery; Transfection; Uterus

1999
Pathophysiological roles of endothelin-1 in Dahl salt-sensitive hypertension.
    Hypertension (Dallas, Tex. : 1979), 1999, Volume: 34, Issue:3

    Topics: Animals; Aorta; Blood Pressure; Endothelin Receptor Antagonists; Endothelin-1; Heart Ventricles; Hypertension; Kidney; Male; Myocardium; Pressoreceptors; Pyridines; Rats; Rats, Inbred Strains; Receptor, Endothelin A; Receptor, Endothelin B; RNA, Messenger; Ventricular Function, Left

1999
Antihypertensive effects of a mixed endothelin-A- and -B-receptor antagonist, J-104132, were augmented in the presence of an AT1 -receptor antagonist, MK-954.
    Journal of cardiovascular pharmacology, 2000, Volume: 36, Issue:5 Suppl 1

    Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Drug Synergism; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Losartan; Male; Protein Precursors; Pyridines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptor, Endothelin A; Receptor, Endothelin B; RNA, Messenger

2000
Pathophysiological roles of endogenous endothelin-1 in dogs with chronic heart failure produced by rapid right ventricular pacing.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 298, Issue:2

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiac Pacing, Artificial; Chronic Disease; Dogs; Echocardiography; Enalaprilat; Endothelin Receptor Antagonists; Endothelin-1; Heart Failure; Hemodynamics; Pyridines; Receptors, Endothelin; Tissue Distribution; Ventricular Function

2001
Endothelin-1-induced impairment of endothelium-dependent relaxation in aortas isolated from controls and diabetic rats.
    Journal of cardiovascular pharmacology, 2004, Volume: 44 Suppl 1

    Topics: Acetylcholine; Animals; Aorta; Chromones; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Endothelium, Vascular; Free Radical Scavengers; Male; Morpholines; Nitroprusside; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Polyethylene Glycols; Protein Kinase Inhibitors; Pyridines; Rats; Rats, Wistar; Receptors, Endothelin; Superoxide Dismutase; Superoxides; Tissue Culture Techniques; Vasodilation; Vasodilator Agents

2004
Endothelin-1 and serotonin are involved in activation of RhoA/Rho kinase signaling in the chronically hypoxic hypertensive rat pulmonary circulation.
    Journal of cardiovascular pharmacology, 2007, Volume: 50, Issue:6

    Topics: Amides; Animals; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; Enzyme Activation; Hypertension, Pulmonary; Hypoxia; In Vitro Techniques; Lung; Male; Peptides, Cyclic; Perfusion; Potassium Chloride; Pulmonary Artery; Pulmonary Circulation; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; rhoA GTP-Binding Protein; Serotonin; Signal Transduction; Vasoconstriction

2007
Endothelin ETB receptor is involved in sex differences in the development of balloon injury-induced neointimal formation.
    The Journal of pharmacology and experimental therapeutics, 2011, Volume: 336, Issue:2

    Topics: Animals; Catheterization; Endothelin-1; Estrogens; Female; Male; Neointima; Ovariectomy; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Endothelin A; Receptor, Endothelin B; RNA, Messenger; Sex Characteristics; Systole

2011