l 741626 has been researched along with sb 277011 in 13 studies
| Studies (l 741626) | Trials (l 741626) | Recent Studies (post-2010) (l 741626) | Studies (sb 277011) | Trials (sb 277011) | Recent Studies (post-2010) (sb 277011) |
|---|---|---|---|---|---|
| 76 | 0 | 33 | 98 | 0 | 41 |
| Protein | Taxonomy | l 741626 (IC50) | sb 277011 (IC50) |
|---|---|---|---|
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 1.6598 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 9 (69.23) | 24.3611 |
| 2020's | 2 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Jadhav, A; Kerns, E; Nguyen, K; Shah, P; Sun, H; Xu, X; Yan, Z; Yu, KR | 1 |
| Kabir, M; Kerns, E; Nguyen, K; Shah, P; Sun, H; Wang, Y; Xu, X; Yu, KR | 1 |
| Kabir, M; Kerns, E; Neyra, J; Nguyen, K; Nguyễn, ÐT; Shah, P; Siramshetty, VB; Southall, N; Williams, J; Xu, X; Yu, KR | 1 |
| Itkin, M; Kabir, M; Mathé, EA; Nguyễn, ÐT; Padilha, EC; Shah, P; Shinn, P; Siramshetty, V; Wang, AQ; Williams, J; Xu, X; Yu, KR; Zhao, T | 1 |
| Loiseau, F; Millan, MJ | 1 |
| Gross, G; Jongen-Rêlo, AL; Schoemaker, H; Unger, L; van Gaalen, MM | 1 |
| Bernedo, VE; Chen, R; Kilb, W; Kolbaev, SN; Luhmann, HJ; Moser, J; Sharopov, S; Werhahn, KJ | 1 |
| Davoodi, N; Langlois, X; te Riele, P | 1 |
| Di Ciano, P; Diaz, J; Khaled, MA; Le Foll, B; Pushparaj, A | 1 |
| Dulawa, SC; Ho, EV; Klenotich, SJ; McMurray, MS; Server, CH | 1 |
| Newton, CL; Strange, PG; Wood, MD | 1 |
| Jones, SR; McGinnis, MM; Siciliano, CA | 1 |
| Baumann, MH; Humburg, BA; Jordan, CJ; Newman, AH; Schindler, CW; Shaik, AB; Thorndike, EB; Xi, ZX | 1 |
1 review(s) available for l 741626 and sb 277011
| Article | Year |
|---|---|
Using in vitro ADME data for lead compound selection: An emphasis on PAMPA pH 5 permeability and oral bioavailability.
Topics: Administration, Oral; Animals; Betamethasone; Biological Availability; Caco-2 Cells; Cell Membrane Permeability; Cells, Cultured; Dexamethasone; Dogs; Dose-Response Relationship, Drug; Humans; Hydrogen-Ion Concentration; Madin Darby Canine Kidney Cells; Mice; Molecular Structure; Neural Networks, Computer; Ranitidine; Rats; Structure-Activity Relationship; Verapamil | 2022 |
12 other study(ies) available for l 741626 and sb 277011
| Article | Year |
|---|---|
Highly predictive and interpretable models for PAMPA permeability.
Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Humans; Models, Biological; Organic Chemicals; Regression Analysis; Support Vector Machine | 2017 |
Predictive models of aqueous solubility of organic compounds built on A large dataset of high integrity.
Topics: Drug Discovery; Organic Chemicals; Pharmaceutical Preparations; Solubility | 2019 |
Retrospective assessment of rat liver microsomal stability at NCATS: data and QSAR models.
Topics: Animals; Computer Simulation; Databases, Factual; Drug Discovery; High-Throughput Screening Assays; Liver; Machine Learning; Male; Microsomes, Liver; National Center for Advancing Translational Sciences (U.S.); Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Rats; Rats, Sprague-Dawley; Retrospective Studies; United States | 2020 |
Blockade of dopamine D(3) receptors in frontal cortex, but not in sub-cortical structures, enhances social recognition in rats: similar actions of D(1) receptor agonists, but not of D(2) antagonists.
Topics: Animals; Benzazepines; Benzopyrans; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Indoles; Male; Microinjections; Nitriles; Piperidines; Prefrontal Cortex; Pyrroles; Rats; Rats, Wistar; Receptors, Dopamine D1; Receptors, Dopamine D3; Recognition, Psychology; Social Behavior; Tetrahydroisoquinolines | 2009 |
Amphetamine decreases behavioral inhibition by stimulation of dopamine D2, but not D3, receptors.
Topics: Amphetamine; Animals; Cell Line, Transformed; Central Nervous System Stimulants; Choice Behavior; Conditioning, Operant; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Humans; Indoles; Inhibition, Psychological; Male; Nitriles; Piperidines; Protein Binding; Radioligand Assay; Rats; Rats, Wistar; Reaction Time; Receptors, Dopamine D2; Receptors, Dopamine D3; Tetrahydroisoquinolines | 2009 |
Dopaminergic modulation of low-Mg²⁺-induced epileptiform activity in the intact hippocampus of the newborn mouse in vitro.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Animals, Newborn; Benzazepines; Data Interpretation, Statistical; Dopamine; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Epilepsy; Hippocampus; Indoles; Magnesium Deficiency; Mice; Mice, Inbred C57BL; Nitriles; Piperidines; Quinpirole; Receptors, Dopamine D2; Synapses; Tetrahydroisoquinolines | 2012 |
Examining dopamine D3 receptor occupancy by antipsychotic drugs via [3H]7-OH-DPAT ex vivo autoradiography and its cross-validation via c-fos immunohistochemistry in the rat brain.
Topics: Animals; Antipsychotic Agents; Autoradiography; Benzodiazepines; Clozapine; Dopamine Antagonists; Haloperidol; Indoles; Islands of Calleja; Male; Nitriles; Olanzapine; Piperidines; Proto-Oncogene Proteins c-fos; Radiography; Rats, Wistar; Receptors, Dopamine D2; Receptors, Dopamine D3; Tetrahydroisoquinolines; Tetrahydronaphthalenes | 2014 |
Dopamine D3 receptors in the basolateral amygdala and the lateral habenula modulate cue-induced reinstatement of nicotine seeking.
Topics: Animals; Autoradiography; Basolateral Nuclear Complex; Conditioning, Operant; Cues; Dopamine Antagonists; Drug-Seeking Behavior; Extinction, Psychological; Habenula; Indoles; Iodine Isotopes; Male; Nicotine; Nicotinic Agonists; Nitriles; Piperidines; Rats; Rats, Long-Evans; Receptors, Dopamine D3; Reinforcement, Psychology; Self Administration; Tetrahydroisoquinolines; Tetrahydronaphthalenes | 2014 |
Dopamine D2/3 receptor antagonism reduces activity-based anorexia.
Topics: Amisulpride; Animals; Anorexia Nervosa; Benzodiazepines; Disease Models, Animal; Dopamine D2 Receptor Antagonists; Eating; Female; Indoles; Mice; Mice, Inbred BALB C; Motor Activity; Nitriles; Olanzapine; Piperidines; Receptors, Dopamine D3; Salicylamides; Sulpiride; Tetrahydroisoquinolines; Weight Loss | 2015 |
Examining the Effects of Sodium Ions on the Binding of Antagonists to Dopamine D2 and D3 Receptors.
Topics: Animals; Binding, Competitive; Biphenyl Compounds; Cell Line, Tumor; Dopamine Agonists; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Humans; Indans; Indoles; Ions; Ligands; Molecular Structure; Mutation; Nitriles; Piperazines; Piperidines; Radioligand Assay; Receptors, Dopamine D2; Receptors, Dopamine D3; Sf9 Cells; Sodium; Spodoptera; Tetrahydroisoquinolines | 2016 |
Dopamine D3 autoreceptor inhibition enhances cocaine potency at the dopamine transporter.
Topics: Animals; Autoreceptors; Cocaine; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Drug Synergism; Female; Indoles; Male; Mice; Mice, Inbred C57BL; Nitriles; Piperidines; Raclopride; Receptors, Dopamine D2; Receptors, Tumor Necrosis Factor, Member 25; Sex Characteristics; Tetrahydroisoquinolines | 2016 |
Newly Developed Dopamine D
Topics: Animals; Blood Pressure; Cocaine; Dopamine Antagonists; Dose-Response Relationship, Drug; Heart Rate; Indoles; Male; Nitriles; Oxycodone; Piperazines; Piperidines; Rats; Rats, Long-Evans; Receptors, Dopamine D3; Tetrahydroisoquinolines | 2019 |