Page last updated: 2024-09-04

l 741626 and olanzapine

l 741626 has been researched along with olanzapine in 3 studies

Compound Research Comparison

Studies
(l 741626)
Trials
(l 741626)
Recent Studies (post-2010)
(l 741626)
Studies
(olanzapine)
Trials
(olanzapine)
Recent Studies (post-2010) (olanzapine)
760336,3391,3402,383

Protein Interaction Comparison

ProteinTaxonomyl 741626 (IC50)olanzapine (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.097
Muscarinic acetylcholine receptor M4Homo sapiens (human)0.155
5-hydroxytryptamine receptor 2CRattus norvegicus (Norway rat)0.047
Muscarinic acetylcholine receptor M5Homo sapiens (human)0.04
Alpha-2A adrenergic receptorHomo sapiens (human)0.541
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)2.768
D(2) dopamine receptorHomo sapiens (human)0.118
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)0.047
Alpha-2B adrenergic receptorHomo sapiens (human)0.421
Alpha-2C adrenergic receptorHomo sapiens (human)0.531
Muscarinic acetylcholine receptor M3Homo sapiens (human)0.392
D(1A) dopamine receptorHomo sapiens (human)0.072
D(4) dopamine receptorHomo sapiens (human)0.173
Alpha-1D adrenergic receptorHomo sapiens (human)0.092
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.038
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.021
5-hydroxytryptamine receptor 2BRattus norvegicus (Norway rat)0.047
Sodium-dependent serotonin transporterHomo sapiens (human)1.033
Histamine H1 receptorHomo sapiens (human)0.013
D(3) dopamine receptorHomo sapiens (human)0.078
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.057
5-hydroxytryptamine receptor 6Homo sapiens (human)0.013
D(2) dopamine receptorRattus norvegicus (Norway rat)0.158
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.2028

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abe, M; Egashira, N; Fujiwara, M; Iwasaki, K; Matsushita, M; Mishima, K; Nishimura, R; Oishi, R; Okuno, R1
Davoodi, N; Langlois, X; te Riele, P1
Dulawa, SC; Ho, EV; Klenotich, SJ; McMurray, MS; Server, CH1

Other Studies

3 other study(ies) available for l 741626 and olanzapine

ArticleYear
Aripiprazole inhibits marble-burying behavior via 5-hydroxytryptamine (5-HT)1A receptor-independent mechanisms.
    European journal of pharmacology, 2008, Sep-11, Volume: 592, Issue:1-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antipsychotic Agents; Anxiety; Aripiprazole; Behavior, Animal; Benzodiazepines; Catalepsy; Dopamine Agonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Indoles; Ketanserin; Male; Mice; Mice, Inbred ICR; Olanzapine; Piperazines; Piperidines; Postural Balance; Psychomotor Performance; Pyridines; Quinolones; Quinpirole; Receptor, Serotonin, 5-HT1A; Receptors, Dopamine D2; Serotonin Antagonists; Serotonin Receptor Agonists

2008
Examining dopamine D3 receptor occupancy by antipsychotic drugs via [3H]7-OH-DPAT ex vivo autoradiography and its cross-validation via c-fos immunohistochemistry in the rat brain.
    European journal of pharmacology, 2014, Oct-05, Volume: 740

    Topics: Animals; Antipsychotic Agents; Autoradiography; Benzodiazepines; Clozapine; Dopamine Antagonists; Haloperidol; Indoles; Islands of Calleja; Male; Nitriles; Olanzapine; Piperidines; Proto-Oncogene Proteins c-fos; Radiography; Rats, Wistar; Receptors, Dopamine D2; Receptors, Dopamine D3; Tetrahydroisoquinolines; Tetrahydronaphthalenes

2014
Dopamine D2/3 receptor antagonism reduces activity-based anorexia.
    Translational psychiatry, 2015, Aug-04, Volume: 5

    Topics: Amisulpride; Animals; Anorexia Nervosa; Benzodiazepines; Disease Models, Animal; Dopamine D2 Receptor Antagonists; Eating; Female; Indoles; Mice; Mice, Inbred BALB C; Motor Activity; Nitriles; Olanzapine; Piperidines; Receptors, Dopamine D3; Salicylamides; Sulpiride; Tetrahydroisoquinolines; Weight Loss

2015