l 741626 has been researched along with haloperidol in 16 studies
| Studies (l 741626) | Trials (l 741626) | Recent Studies (post-2010) (l 741626) | Studies (haloperidol) | Trials (haloperidol) | Recent Studies (post-2010) (haloperidol) |
|---|---|---|---|---|---|
| 76 | 0 | 33 | 20,330 | 1,753 | 3,294 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (6.25) | 18.2507 |
| 2000's | 7 (43.75) | 29.6817 |
| 2010's | 6 (37.50) | 24.3611 |
| 2020's | 2 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Baker, R; Broughton, HB; Curtis, NR; Emms, F; Freedman, SB; Kulagowski, JJ; Leeson, PD; Marwood, R; Mawer, IM; Patel, S; Ragan, CI; Ridgill, MP | 1 |
| Fang, X; Hu, Z; Levant, B; Min, J; Varady, J; Wang, S; Wu, X | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Ablordeppey, SY; Altundas, R; Nkansah, NT; Roth, BL; Setola, V; Sikazwe, DM; Zhu, XY | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Babic, S; Calvin, W; Cui, J; Luedtke, RR; Mach, RH; Taylor, M; Vangveravong, S; Xu, J | 1 |
| Barnaeva, E; Bryant-Genevier, M; Conroy, JL; Doyle, T; Dulcey, AE; Ferrer, M; Free, RB; Hu, X; Marugan, JJ; Miller, B; Sibley, DR; Southall, N; Taylor, MK; Titus, S; Xiao, J; Zheng, W | 1 |
| Jadhav, A; Kerns, E; Nguyen, K; Shah, P; Sun, H; Xu, X; Yan, Z; Yu, KR | 1 |
| Kabir, M; Kerns, E; Nguyen, K; Shah, P; Sun, H; Wang, Y; Xu, X; Yu, KR | 1 |
| Kabir, M; Kerns, E; Neyra, J; Nguyen, K; Nguyễn, ÐT; Shah, P; Siramshetty, VB; Southall, N; Williams, J; Xu, X; Yu, KR | 1 |
| Itkin, M; Kabir, M; Mathé, EA; Nguyễn, ÐT; Padilha, EC; Shah, P; Shinn, P; Siramshetty, V; Wang, AQ; Williams, J; Xu, X; Yu, KR; Zhao, T | 1 |
| Fushiki, T; Imaizumi, M; Takeda, M | 1 |
| Bergeron, J; Courtney, C; McConkey, M; Melch, M; Shrikhande, A; Smith, D; Wong, SK | 1 |
| Hattori, K; Isosaka, T; Iyo, M; Kohsaka, S; Maekawa, M; Sato, T; Uchino, S; Yagi, T; Yuasa, S | 1 |
| Arai, Y; Kikuchi, T; Mitazaki, S; Nakagawasai, O; Nakaya, K; Niijima, F; Onogi, H; Sato, A; Tadano, T; Tan-No, K | 1 |
| Davoodi, N; Langlois, X; te Riele, P | 1 |
1 review(s) available for l 741626 and haloperidol
| Article | Year |
|---|---|
Using in vitro ADME data for lead compound selection: An emphasis on PAMPA pH 5 permeability and oral bioavailability.
Topics: Administration, Oral; Animals; Betamethasone; Biological Availability; Caco-2 Cells; Cell Membrane Permeability; Cells, Cultured; Dexamethasone; Dogs; Dose-Response Relationship, Drug; Humans; Hydrogen-Ion Concentration; Madin Darby Canine Kidney Cells; Mice; Molecular Structure; Neural Networks, Computer; Ranitidine; Rats; Structure-Activity Relationship; Verapamil | 2022 |
15 other study(ies) available for l 741626 and haloperidol
| Article | Year |
|---|---|
3-((4-(4-Chlorophenyl)piperazin-1-yl)-methyl)-1H-pyrrolo-2,3-b-pyridine: an antagonist with high affinity and selectivity for the human dopamine D4 receptor.
Topics: Animals; Cell Line; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Humans; Pyridines; Pyrroles; Receptors, Dopamine D4 | 1996 |
Molecular modeling of the three-dimensional structure of dopamine 3 (D3) subtype receptor: discovery of novel and potent D3 ligands through a hybrid pharmacophore- and structure-based database searching approach.
Topics: Algorithms; Binding Sites; Computational Biology; Crystallography, X-Ray; Databases, Protein; Humans; Kinetics; Ligands; Lipid Bilayers; Models, Molecular; Molecular Conformation; Mutation; Receptors, Dopamine D2; Receptors, Dopamine D3; Reproducibility of Results; Solvents; Structure-Activity Relationship; Tetrahydronaphthalenes; Water | 2003 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Synthesis and evaluation of ligands for D2-like receptors: the role of common pharmacophoric groups.
Topics: Antipsychotic Agents; Binding Sites; Butyrophenones; Haloperidol; Humans; Indoles; Kinetics; Ligands; Receptors, Dopamine D2; Structure-Activity Relationship | 2009 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Synthesis and characterization of selective dopamine D2 receptor antagonists. 2. Azaindole, benzofuran, and benzothiophene analogs of L-741,626.
Topics: Adenylyl Cyclases; Benzofurans; Cell Line; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Humans; Indoles; Protein Binding; Receptors, Dopamine D2; Thiophenes | 2010 |
Discovery, optimization, and characterization of novel D2 dopamine receptor selective antagonists.
Topics: Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Drug Discovery; HEK293 Cells; High-Throughput Screening Assays; Humans; Structure-Activity Relationship | 2014 |
Highly predictive and interpretable models for PAMPA permeability.
Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Humans; Models, Biological; Organic Chemicals; Regression Analysis; Support Vector Machine | 2017 |
Predictive models of aqueous solubility of organic compounds built on A large dataset of high integrity.
Topics: Drug Discovery; Organic Chemicals; Pharmaceutical Preparations; Solubility | 2019 |
Retrospective assessment of rat liver microsomal stability at NCATS: data and QSAR models.
Topics: Animals; Computer Simulation; Databases, Factual; Drug Discovery; High-Throughput Screening Assays; Liver; Machine Learning; Male; Microsomes, Liver; National Center for Advancing Translational Sciences (U.S.); Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Rats; Rats, Sprague-Dawley; Retrospective Studies; United States | 2020 |
Effects of oil intake in the conditioned place preference test in mice.
Topics: Animals; Behavior, Animal; Benzazepines; Brain Chemistry; Conditioning, Psychological; Corn Oil; Dopamine Antagonists; Eating; Haloperidol; Indoles; Male; Mice; Piperidines; Receptors, Dopamine D1; Reward; Space Perception; Sulpiride | 2000 |
Fully automated radioligand binding filtration assay for membrane-bound receptors.
Topics: Animals; Automation; Binding, Competitive; CHO Cells; Cricetinae; Filtration; Haloperidol; Indoles; Piperidines; Radioligand Assay; Receptors, Dopamine; Reproducibility of Results; Time Factors | 2002 |
Fyn is required for haloperidol-induced catalepsy in mice.
Topics: Animals; Anti-Dyskinesia Agents; Antipsychotic Agents; Blotting, Western; Calcium; Catalepsy; Cells, Cultured; Dopamine; Genotype; Haloperidol; Immunoblotting; Immunohistochemistry; Immunoprecipitation; In Situ Hybridization; Indoles; Mice; Neurons; Phosphorylation; Piperidines; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-fyn; Receptors, Dopamine D2; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Time Factors; Tyrosine | 2006 |
p-Hydroxyamphetamine causes prepulse inhibition disruptions in mice: contribution of dopamine neurotransmission.
Topics: Animals; Benzazepines; Clozapine; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Haloperidol; Indoles; Injections, Intraventricular; Male; Mice; Mice, Inbred Strains; Oxidopamine; p-Hydroxyamphetamine; Piperazines; Piperidines; Pyridines; Pyrroles; Reflex, Startle; Salicylamides; Sensory Gating; Sympathomimetics; Synaptic Transmission | 2010 |
Examining dopamine D3 receptor occupancy by antipsychotic drugs via [3H]7-OH-DPAT ex vivo autoradiography and its cross-validation via c-fos immunohistochemistry in the rat brain.
Topics: Animals; Antipsychotic Agents; Autoradiography; Benzodiazepines; Clozapine; Dopamine Antagonists; Haloperidol; Indoles; Islands of Calleja; Male; Nitriles; Olanzapine; Piperidines; Proto-Oncogene Proteins c-fos; Radiography; Rats, Wistar; Receptors, Dopamine D2; Receptors, Dopamine D3; Tetrahydroisoquinolines; Tetrahydronaphthalenes | 2014 |