Page last updated: 2024-09-03

l 703606 and 7,7-diphenyl-2-(1-imino-2-(2-methoxyphenyl)ethyl)perhydroisoindol-4-one

l 703606 has been researched along with 7,7-diphenyl-2-(1-imino-2-(2-methoxyphenyl)ethyl)perhydroisoindol-4-one in 2 studies

Compound Research Comparison

Studies (l 703606)	Trials (l 703606)	Recent Studies (post-2010) (l 703606)	Studies (7,7-diphenyl-2-(1-imino-2-(2-methoxyphenyl)ethyl)perhydroisoindol-4-one)	Trials (7,7-diphenyl-2-(1-imino-2-(2-methoxyphenyl)ethyl)perhydroisoindol-4-one)	Recent Studies (post-2010) (7,7-diphenyl-2-(1-imino-2-(2-methoxyphenyl)ethyl)perhydroisoindol-4-one)
74	0	12	217	0	16

Protein Interaction Comparison

Protein	Taxonomy	l 703606 (IC50)	7,7-diphenyl-2-(1-imino-2-(2-methoxyphenyl)ethyl)perhydroisoindol-4-one (IC50)
Substance-P receptor	Homo sapiens (human)		0.03
Substance-P receptor	Cavia porcellus (domestic guinea pig)		0.032

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (50.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bollinger, RR; Maggio, JE; Mantyh, CR; Mantyh, PW; Pappas, TN; Vigna, SR	1
Sachs, JR; Wang, DH; Xie, C	1

Other Studies

2 other study(ies) available for l 703606 and 7,7-diphenyl-2-(1-imino-2-(2-methoxyphenyl)ethyl)perhydroisoindol-4-one

Article	Year
Substance P binding sites on intestinal lymphoid aggregates and blood vessels in inflammatory bowel disease correspond to authentic NK-1 receptors. Neuroscience letters, 1994, Sep-12, Volume: 178, Issue:2 Topics: Binding Sites; Biphenyl Compounds; Blood Vessels; Humans; Indoles; Inflammatory Bowel Diseases; Intestinal Mucosa; Intestines; Isoindoles; Lymphoid Tissue; Neurokinin-1 Receptor Antagonists; Quinuclidines; Receptors, Neurokinin-1; Substance P	1994
Interdependent regulation of afferent renal nerve activity and renal function: role of transient receptor potential vanilloid type 1, neurokinin 1, and calcitonin gene-related peptide receptors. The Journal of pharmacology and experimental therapeutics, 2008, Volume: 325, Issue:3 Topics: Animals; Blood Pressure; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Capsaicin; Ganglia, Spinal; Isoindoles; Kidney Pelvis; Male; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Peptide Fragments; Quinuclidines; Rats; Rats, Wistar; Receptors, Calcitonin Gene-Related Peptide; Receptors, Neurokinin-1; Substance P; TRPV Cation Channels	2008

Article

Year

Substance P binding sites on intestinal lymphoid aggregates and blood vessels in inflammatory bowel disease correspond to authentic NK-1 receptors.

Neuroscience letters, 1994, Sep-12, Volume: 178, Issue:2

Topics: Binding Sites; Biphenyl Compounds; Blood Vessels; Humans; Indoles; Inflammatory Bowel Diseases; Intestinal Mucosa; Intestines; Isoindoles; Lymphoid Tissue; Neurokinin-1 Receptor Antagonists; Quinuclidines; Receptors, Neurokinin-1; Substance P

1994

Interdependent regulation of afferent renal nerve activity and renal function: role of transient receptor potential vanilloid type 1, neurokinin 1, and calcitonin gene-related peptide receptors.

The Journal of pharmacology and experimental therapeutics, 2008, Volume: 325, Issue:3

Topics: Animals; Blood Pressure; Calcitonin Gene-Related Peptide; Calcitonin Gene-Related Peptide Receptor Antagonists; Capsaicin; Ganglia, Spinal; Isoindoles; Kidney Pelvis; Male; Neurokinin-1 Receptor Antagonists; Neurons, Afferent; Peptide Fragments; Quinuclidines; Rats; Rats, Wistar; Receptors, Calcitonin Gene-Related Peptide; Receptors, Neurokinin-1; Substance P; TRPV Cation Channels

2008