l 694247 and oxadiazoles
l 694247 has been researched along with oxadiazoles in 23 studies
Compound Research Comparison
| Studies (l 694247) | Trials (l 694247) | Recent Studies (post-2010) (l 694247) | Studies (oxadiazoles) | Trials (oxadiazoles) | Recent Studies (post-2010) (oxadiazoles) |
|---|---|---|---|---|---|
| 32 | 0 | 8 | 6,057 | 257 | 2,359 |
Research
Studies (23)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 12 (52.17) | 18.2507 |
| 2000's | 6 (26.09) | 29.6817 |
| 2010's | 5 (21.74) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Beer, MS; Heald, A; Middlemiss, DN; Osborne, SA; Stanton, JA | 1 |
| Beer, MS; Bevan, Y; Hargreaves, RJ; Heald, A; Matassa, VG; Middlemiss, DN; Reeve, AJ; Stanton, JA; Street, LJ | 1 |
| Frölich, D; Göthert, M; Likungu, J; Molderings, GJ | 1 |
| Böing, C; Bühlen, M; Fink, K; Göthert, M | 1 |
| Bulcäo, C; Cunha, M; De Castro-e-Silva, E; De Oliveira, IR; Fregoneze, JB; Luz, CP; Marinho, A; Nascimento, TA; Sarmento, C; Soares, T | 1 |
| Colpaert, FC; Dupuis, DS; Palmier, C; Pauwels, PJ | 1 |
| Gean, PW; Lu, KT | 1 |
| Colpaert, FC; Dupuis, DS; Halazy, S; Pauwels, PJ; Perez, M | 1 |
| Durham, PL; Russo, AF | 1 |
| Dupuis, DS; Hall, H; Pauwels, PJ; Radu, D | 1 |
| Alper, RH; Mize, AL | 1 |
| Bult, H; Geerts, IS; Herman, AG; Matthys, KE | 1 |
| Sibella-Argüelles, C | 1 |
| Araujo-Alvarez, JM; Delgado, A; Oviedo-Chávez, A; Querejeta, E; Quiñones-Cárdenas, AR | 1 |
| Calama, E; Martín, ML; Morán, A; Ortíz de Urbina, AV; San Román, L | 1 |
| Odagaki, Y; Toyoshima, R | 1 |
| Barthelmebs, M; García, M; Luisa Martín, M; Morán, A; San Román, L | 1 |
| García, M; Martín, ML; Morán, A; Ortizde Urbina, AV; San Román, L | 1 |
| Hadley, JK; Halliwell, JV | 1 |
| Bruce, G; Clapcote, SJ; Deuchars, J; Deuchars, SA; Edwards, IJ; Howe, L; Lawrenson, C | 1 |
| García, M; García-Pedraza, JÁ; Martín, ML; Morán, A | 1 |
| García, M; García-Pedraza, JA; Martín, ML; Morán, A; Rodríguez-Barbero, A | 1 |
| García-Domingo, M; García-Pedraza, JÁ; Gómez-Roso, M; López, C; Martín, ML; Morán, A | 1 |
Other Studies
23 other study(ies) available for l 694247 and oxadiazoles
| Article | Year |
|---|---|
[3H]L-694,247 labels the 5-HT1D beta receptor in pig caudate membranes.
Topics: Animals; Binding, Competitive; Caudate Nucleus; Frozen Sections; Oxadiazoles; Radioligand Assay; Receptors, Serotonin; Serotonin Receptor Agonists; Structure-Activity Relationship; Swine; Tissue Preservation; Tryptamines | 1994 |
L-694,247: a potent 5-HT1D receptor agonist.
Topics: Adenylyl Cyclases; Animals; Cerebral Cortex; Colforsin; Frontal Lobe; In Vitro Techniques; Oxadiazoles; Potassium; Radioligand Assay; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists; Stimulation, Chemical; Substantia Nigra; Swine; Tritium; Tryptamines | 1993 |
Inhibition of noradrenaline release via presynaptic 5-HT1D alpha receptors in human atrium.
Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic Uptake Inhibitors; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cisapride; Corticosterone; Desipramine; Heart Atria; Humans; Indoles; Ketanserin; Male; Middle Aged; Norepinephrine; Oxadiazoles; Piperidines; Receptors, Presynaptic; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sumatriptan; Tritium; Tryptamines | 1996 |
Evidence for presynaptic location of inhibitory 5-HT1D beta-like autoreceptors in the guinea-pig brain cortex.
Topics: Animals; Autoreceptors; Binding, Competitive; Cerebral Cortex; Guinea Pigs; Humans; Indoles; Ketanserin; Male; Methiothepin; Oxadiazoles; Oxymetazoline; Potassium; Radioligand Assay; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship; Sumatriptan; Synaptosomes; Tritium; Tryptamines | 1996 |
Effect of third ventricle administration of L-694,247, a selective 5-HT1D receptor agonist, on water intake in rats.
Topics: Adrenergic beta-Agonists; Angiotensin II; Animals; Carbachol; Drinking; Injections, Intraventricular; Isoproterenol; Male; Microinjections; Muscarinic Agonists; Oxadiazoles; Piperazines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tryptamines; Water Deprivation | 1997 |
Autoradiography of serotonin 5-HT1A receptor-activated G proteins in guinea pig brain sections by agonist-stimulated [35S]GTPgammaS binding.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoradiography; Brain Chemistry; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Hippocampus; Male; Oxadiazoles; Piperazines; Raphe Nuclei; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Septal Nuclei; Serotonin Receptor Agonists; Sulfur Radioisotopes; Tryptamines | 1998 |
Endogenous serotonin inhibits epileptiform activity in rat hippocampal CA1 neurons via 5-hydroxytryptamine1A receptor activation.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Barium; Epilepsy; Excitatory Postsynaptic Potentials; Fluoxetine; Hippocampus; In Vitro Techniques; Ketanserin; Male; Membrane Potentials; Metergoline; Neurons; Oxadiazoles; Picrotoxin; Piperazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Synaptic Transmission; Tryptamines | 1998 |
Magnitude of 5-HT1B and 5-HT1A receptor activation in guinea-pig and rat brain: evidence from sumatriptan dimer-mediated [35S]GTPgammaS binding responses.
Topics: Animals; Autoradiography; Binding, Competitive; Brain Chemistry; Dimerization; Glioma; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guinea Pigs; HeLa Cells; Humans; Male; Membrane Proteins; Oxadiazoles; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists; Sulfur Radioisotopes; Sumatriptan; Tryptamines | 1999 |
Regulation of calcitonin gene-related peptide secretion by a serotonergic antimigraine drug.
Topics: Animals; Animals, Newborn; Calcitonin Gene-Related Peptide; Cells, Cultured; Colforsin; Cyclic AMP; HeLa Cells; Humans; Inflammation; Kinetics; Models, Neurological; Neurons; Okadaic Acid; Oxadiazoles; Potassium Chloride; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Recombinant Proteins; Serotonin Receptor Agonists; Sumatriptan; Transfection; Trigeminal Ganglion; Tryptamines | 1999 |
Autoradiographic studies of 5-HT1A-receptor-stimulated [35S]GTPgammaS-binding responses in the human and monkey brain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoradiography; Binding, Competitive; Brain Chemistry; Female; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Indoles; Macaca fascicularis; Male; Oxadiazoles; Piperazines; Piperidines; Pyridines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfur Radioisotopes; Tritium; Tryptamines | 1999 |
Serotonin 5-HT(1B/1D) agonist-stimulated [(35)S]GTPgammaS binding in rat and guinea pig striatal membranes.
Topics: Animals; Corpus Striatum; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Male; Membranes; Oxadiazoles; Pyridines; Pyrroles; Radioligand Assay; Rats; Serotonin; Serotonin Receptor Agonists; Stimulation, Chemical; Sulfur Radioisotopes; Tryptamines | 1999 |
Involvement of 5-HT1B receptors in collar-induced hypersensitivity to 5-hydroxytryptamine of the rabbit carotid artery.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Braces; Carotid Arteries; Dose-Response Relationship, Drug; Hypersensitivity; In Vitro Techniques; Ketanserin; Male; Methysergide; Oxadiazoles; Piperazines; Potassium Chloride; Rabbits; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone; Sumatriptan; Tryptamines; Vasoconstriction | 1999 |
The proliferation of human T lymphoblastic cells induced by 5-HT1B receptors activation is regulated by 5-HT-moduline.
Topics: Acrylamides; Cell Division; Humans; Indoles; Leukemia-Lymphoma, Adult T-Cell; Lipopolysaccharides; Neuropeptides; Oligopeptides; Oxadiazoles; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; T-Lymphocytes; Tryptamines; Tumor Cells, Cultured | 2001 |
In vivo effects of local activation and blockade of 5-HT1B receptors on globus pallidus neuronal spiking.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Anesthesia; Animals; Behavior, Animal; Denervation; Fluoxetine; Globus Pallidus; Male; Methiothepin; Neurons; Oxadiazoles; Piperazines; Pyridines; Quinolinic Acid; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1B; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists; Tryptamines | 2005 |
Effect of 5-hydroxytryptamine on neurogenic vasoconstriction in the isolated, autoperfused hindquarters of the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Biguanides; Biphenyl Compounds; Dose-Response Relationship, Drug; Electric Stimulation; Hindlimb; In Vitro Techniques; Infusions, Intravenous; Male; Methiothepin; Oxadiazoles; Perfusion; Piperazines; Pressure; Quinoxalines; Rats; Rats, Wistar; Ritanserin; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT3 Receptor Agonists; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists; Tryptamines; Vasoconstriction | 2005 |
5-HT-stimulated [35S]guanosine-5'-O-(3-thio)triphosphate binding as an assay for functional activation of G proteins coupled with 5-HT1B receptors in rat striatal membranes.
Topics: Animals; Binding, Competitive; Corpus Striatum; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); In Vitro Techniques; Male; Oxadiazoles; Pindolol; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT1B; Serotonin; Serotonin Agents; Sulfur Radioisotopes; Tryptamines | 2006 |
The nitric oxide synthesis/pathway mediates the inhibitory serotoninergic responses of the pressor effect elicited by sympathetic stimulation in diabetic pithed rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Atropine; Blood Pressure; Diabetes Mellitus, Experimental; Electric Stimulation; Enzyme Inhibitors; Guanylate Cyclase; Male; Muscarinic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin Receptor Agonists; Spinal Cord; Tryptamines; Vasoconstriction | 2006 |
Diabetes-induced changes in 5-hydroxytryptamine modulation of vagally-induced bradycardia in rat heart.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Animals; Biphenyl Compounds; Blood Glucose; Bradycardia; Cholinergic Agents; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Electric Stimulation; Ergolines; Heart; Heart Rate; Injections, Intravenous; Male; Methiothepin; Oxadiazoles; Piperazines; Pyridines; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tryptamines; Vagus Nerve | 2007 |
Serotonin modulates glutamatergic transmission in the rat olfactory tubercle.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Citalopram; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Male; Olfactory Pathways; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists; Synaptic Transmission; Tryptamines | 2010 |
Na+/K+ ATPase α1 and α3 isoforms are differentially expressed in α- and γ-motoneurons.
Topics: Action Potentials; Animals; Animals, Newborn; Anterior Horn Cells; Enzyme Inhibitors; Female; Ganglia, Spinal; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Motor Neurons, Gamma; Ouabain; Oxadiazoles; Parvalbumins; Patch-Clamp Techniques; Serotonin Antagonists; Sodium-Potassium-Exchanging ATPase; Spinal Cord; Tryptamines | 2013 |
5-HT1D receptor inhibits renal sympathetic neurotransmission by nitric oxide pathway in anesthetized rats.
Topics: Animals; Blood Pressure; Heart Rate; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Sympathetic Nervous System; Synaptic Transmission; Tryptamines | 2015 |
5-HT2 receptor blockade exhibits 5-HT vasodilator effects via nitric oxide, prostacyclin and ATP-sensitive potassium channels in rat renal vasculature.
Topics: Animals; Dose-Response Relationship, Drug; Epoprostenol; KATP Channels; Kidney; Male; Nitric Oxide; Oxadiazoles; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT2; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Antagonists; Tryptamines; Vasodilator Agents | 2016 |
Fluoxetine oral treatment discloses 5-HT
Topics: Administration, Oral; Animals; Antidepressive Agents, Second-Generation; Bradycardia; Depression; Disease Models, Animal; Drug Evaluation, Preclinical; Fluoxetine; Heart; Heart Rate; Humans; Oxadiazoles; Phenols; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1D; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Serotonin Receptor Agonists; Sulfonamides; Tryptamines; Vagus Nerve | 2019 |