l 694247 has been researched along with methiothepin in 5 studies
| Studies (l 694247) | Trials (l 694247) | Recent Studies (post-2010) (l 694247) | Studies (methiothepin) | Trials (methiothepin) | Recent Studies (post-2010) (methiothepin) |
|---|---|---|---|---|---|
| 32 | 0 | 8 | 494 | 2 | 62 |
| Protein | Taxonomy | l 694247 (IC50) | methiothepin (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 7 | Homo sapiens (human) | 0.0075 | |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | 0.03 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Grånäs, C; Larhammar, D | 1 |
| Böing, C; Bühlen, M; Fink, K; Göthert, M | 1 |
| Araujo-Alvarez, JM; Delgado, A; Oviedo-Chávez, A; Querejeta, E; Quiñones-Cárdenas, AR | 1 |
| Calama, E; Martín, ML; Morán, A; Ortíz de Urbina, AV; San Román, L | 1 |
| García, M; Martín, ML; Morán, A; Ortizde Urbina, AV; San Román, L | 1 |
5 other study(ies) available for l 694247 and methiothepin
| Article | Year |
|---|---|
Identification of an amino acid residue important for binding of methiothepin and sumatriptan to the human 5-HT(1B) receptor.
Topics: Amino Acid Sequence; Amino Acids; Animals; Benzamides; Binding Sites; Binding, Competitive; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Methiothepin; Molecular Sequence Data; Mutation; Protein Binding; Pyridines; Radioligand Assay; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Sequence Homology, Amino Acid; Serotonin Antagonists; Serotonin Receptor Agonists; Sodium; Sumatriptan; Tritium | 1999 |
Evidence for presynaptic location of inhibitory 5-HT1D beta-like autoreceptors in the guinea-pig brain cortex.
Topics: Animals; Autoreceptors; Binding, Competitive; Cerebral Cortex; Guinea Pigs; Humans; Indoles; Ketanserin; Male; Methiothepin; Oxadiazoles; Oxymetazoline; Potassium; Radioligand Assay; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship; Sumatriptan; Synaptosomes; Tritium; Tryptamines | 1996 |
In vivo effects of local activation and blockade of 5-HT1B receptors on globus pallidus neuronal spiking.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Anesthesia; Animals; Behavior, Animal; Denervation; Fluoxetine; Globus Pallidus; Male; Methiothepin; Neurons; Oxadiazoles; Piperazines; Pyridines; Quinolinic Acid; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1B; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists; Tryptamines | 2005 |
Effect of 5-hydroxytryptamine on neurogenic vasoconstriction in the isolated, autoperfused hindquarters of the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Biguanides; Biphenyl Compounds; Dose-Response Relationship, Drug; Electric Stimulation; Hindlimb; In Vitro Techniques; Infusions, Intravenous; Male; Methiothepin; Oxadiazoles; Perfusion; Piperazines; Pressure; Quinoxalines; Rats; Rats, Wistar; Ritanserin; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT3 Receptor Agonists; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists; Tryptamines; Vasoconstriction | 2005 |
Diabetes-induced changes in 5-hydroxytryptamine modulation of vagally-induced bradycardia in rat heart.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Animals; Biphenyl Compounds; Blood Glucose; Bradycardia; Cholinergic Agents; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Electric Stimulation; Ergolines; Heart; Heart Rate; Injections, Intravenous; Male; Methiothepin; Oxadiazoles; Piperazines; Pyridines; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tryptamines; Vagus Nerve | 2007 |