l 694247 has been researched along with 8-hydroxy-2-(di-n-propylamino)tetralin in 10 studies
| Studies (l 694247) | Trials (l 694247) | Recent Studies (post-2010) (l 694247) | Studies (8-hydroxy-2-(di-n-propylamino)tetralin) | Trials (8-hydroxy-2-(di-n-propylamino)tetralin) | Recent Studies (post-2010) (8-hydroxy-2-(di-n-propylamino)tetralin) |
|---|---|---|---|---|---|
| 32 | 0 | 8 | 3,530 | 7 | 389 |
| Protein | Taxonomy | l 694247 (IC50) | 8-hydroxy-2-(di-n-propylamino)tetralin (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 1A | Homo sapiens (human) | 0.0012 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.0032 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.81 | |
| D(2) dopamine receptor | Bos taurus (cattle) | 0.8 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 0.81 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.81 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 2.8959 | |
| Lysosomal alpha-glucosidase | Bos taurus (cattle) | 0.0021 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (50.00) | 18.2507 |
| 2000's | 4 (40.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Frölich, D; Göthert, M; Likungu, J; Molderings, GJ | 1 |
| Colpaert, FC; Dupuis, DS; Palmier, C; Pauwels, PJ | 1 |
| Gean, PW; Lu, KT | 1 |
| Dupuis, DS; Hall, H; Pauwels, PJ; Radu, D | 1 |
| Bult, H; Geerts, IS; Herman, AG; Matthys, KE | 1 |
| Araujo-Alvarez, JM; Delgado, A; Oviedo-Chávez, A; Querejeta, E; Quiñones-Cárdenas, AR | 1 |
| Calama, E; Martín, ML; Morán, A; Ortíz de Urbina, AV; San Román, L | 1 |
| Barthelmebs, M; García, M; Luisa Martín, M; Morán, A; San Román, L | 1 |
| García, M; Martín, ML; Morán, A; Ortizde Urbina, AV; San Román, L | 1 |
| Hadley, JK; Halliwell, JV | 1 |
10 other study(ies) available for l 694247 and 8-hydroxy-2-(di-n-propylamino)tetralin
| Article | Year |
|---|---|
Inhibition of noradrenaline release via presynaptic 5-HT1D alpha receptors in human atrium.
Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic Uptake Inhibitors; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cisapride; Corticosterone; Desipramine; Heart Atria; Humans; Indoles; Ketanserin; Male; Middle Aged; Norepinephrine; Oxadiazoles; Piperidines; Receptors, Presynaptic; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sumatriptan; Tritium; Tryptamines | 1996 |
Autoradiography of serotonin 5-HT1A receptor-activated G proteins in guinea pig brain sections by agonist-stimulated [35S]GTPgammaS binding.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoradiography; Brain Chemistry; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Hippocampus; Male; Oxadiazoles; Piperazines; Raphe Nuclei; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Septal Nuclei; Serotonin Receptor Agonists; Sulfur Radioisotopes; Tryptamines | 1998 |
Endogenous serotonin inhibits epileptiform activity in rat hippocampal CA1 neurons via 5-hydroxytryptamine1A receptor activation.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Barium; Epilepsy; Excitatory Postsynaptic Potentials; Fluoxetine; Hippocampus; In Vitro Techniques; Ketanserin; Male; Membrane Potentials; Metergoline; Neurons; Oxadiazoles; Picrotoxin; Piperazines; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Synaptic Transmission; Tryptamines | 1998 |
Autoradiographic studies of 5-HT1A-receptor-stimulated [35S]GTPgammaS-binding responses in the human and monkey brain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoradiography; Binding, Competitive; Brain Chemistry; Female; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Indoles; Macaca fascicularis; Male; Oxadiazoles; Piperazines; Piperidines; Pyridines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfur Radioisotopes; Tritium; Tryptamines | 1999 |
Involvement of 5-HT1B receptors in collar-induced hypersensitivity to 5-hydroxytryptamine of the rabbit carotid artery.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Braces; Carotid Arteries; Dose-Response Relationship, Drug; Hypersensitivity; In Vitro Techniques; Ketanserin; Male; Methysergide; Oxadiazoles; Piperazines; Potassium Chloride; Rabbits; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone; Sumatriptan; Tryptamines; Vasoconstriction | 1999 |
In vivo effects of local activation and blockade of 5-HT1B receptors on globus pallidus neuronal spiking.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Anesthesia; Animals; Behavior, Animal; Denervation; Fluoxetine; Globus Pallidus; Male; Methiothepin; Neurons; Oxadiazoles; Piperazines; Pyridines; Quinolinic Acid; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1B; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Serotonin Antagonists; Serotonin Receptor Agonists; Tryptamines | 2005 |
Effect of 5-hydroxytryptamine on neurogenic vasoconstriction in the isolated, autoperfused hindquarters of the rat.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Biguanides; Biphenyl Compounds; Dose-Response Relationship, Drug; Electric Stimulation; Hindlimb; In Vitro Techniques; Infusions, Intravenous; Male; Methiothepin; Oxadiazoles; Perfusion; Piperazines; Pressure; Quinoxalines; Rats; Rats, Wistar; Ritanserin; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT3 Receptor Agonists; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists; Tryptamines; Vasoconstriction | 2005 |
The nitric oxide synthesis/pathway mediates the inhibitory serotoninergic responses of the pressor effect elicited by sympathetic stimulation in diabetic pithed rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Atropine; Blood Pressure; Diabetes Mellitus, Experimental; Electric Stimulation; Enzyme Inhibitors; Guanylate Cyclase; Male; Muscarinic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Norepinephrine; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1A; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin Receptor Agonists; Spinal Cord; Tryptamines; Vasoconstriction | 2006 |
Diabetes-induced changes in 5-hydroxytryptamine modulation of vagally-induced bradycardia in rat heart.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Animals; Biphenyl Compounds; Blood Glucose; Bradycardia; Cholinergic Agents; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Electric Stimulation; Ergolines; Heart; Heart Rate; Injections, Intravenous; Male; Methiothepin; Oxadiazoles; Piperazines; Pyridines; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tryptamines; Vagus Nerve | 2007 |
Serotonin modulates glutamatergic transmission in the rat olfactory tubercle.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Citalopram; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Male; Olfactory Pathways; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists; Synaptic Transmission; Tryptamines | 2010 |