Compounds > l 694247

Page last updated: 2024-09-03

l 694247 and 5-carboxamidotryptamine

l 694247 has been researched along with 5-carboxamidotryptamine in 11 studies

Compound Research Comparison

Studies (l 694247)	Trials (l 694247)	Recent Studies (post-2010) (l 694247)	Studies (5-carboxamidotryptamine)	Trials (5-carboxamidotryptamine)	Recent Studies (post-2010) (5-carboxamidotryptamine)
32	0	8	392	1	36

Protein Interaction Comparison

Protein	Taxonomy	l 694247 (IC50)	5-carboxamidotryptamine (IC50)
5-hydroxytryptamine receptor 1D	Sus scrofa (pig)		0.004

Research

Studies (11)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	7 (63.64)	18.2507
2000's	2 (18.18)	29.6817
2010's	2 (18.18)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Baker, R; Beer, MS; Davey, WB; Guiblin, AR; Jelley, RA; Reeve, AJ; Routledge, H; Sternfeld, F; Street, LJ; Watt, AP	1
Baker, R; Beer, MS; Castro, JL; Chambers, MS; Guiblin, AR; Hobbs, SC; Matassa, VG; Middlemiss, DN; Reeve, AJ; Street, LJ	1
Audinot-Bouchez, V; Chaput, C; Conte, C; Lavielle, G; Lochon, S; Millan, MJ; Newman-Tancredi, A; Verrièle, L	1
Frölich, D; Göthert, M; Likungu, J; Molderings, GJ	1
Böing, C; Bühlen, M; Fink, K; Göthert, M	1
Alper, RH; Mize, AL	1
Bult, H; Geerts, IS; Herman, AG; Matthys, KE	1
Calama, E; Martín, ML; Morán, A; Ortíz de Urbina, AV; San Román, L	1
García, M; Martín, ML; Morán, A; Ortizde Urbina, AV; San Román, L	1
Hadley, JK; Halliwell, JV	1
García, M; García-Pedraza, JÁ; Martín, ML; Morán, A	1

Other Studies

11 other study(ies) available for l 694247 and 5-carboxamidotryptamine

Article	Year
Synthesis and serotonergic activity of N,N-dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethylamine and analogues: potent agonists for 5-HT1D receptors. Journal of medicinal chemistry, 1995, May-12, Volume: 38, Issue:10 Topics: Animals; Rabbits; Rats; Serotonin Receptor Agonists; Structure-Activity Relationship; Triazoles; Tryptamines	1995
Synthesis and serotonergic activity of 5-(oxadiazolyl)tryptamines: potent agonists for 5-HT1D receptors. Journal of medicinal chemistry, 1993, May-28, Volume: 36, Issue:11 Topics: Animals; Binding, Competitive; Brain; In Vitro Techniques; Oxadiazoles; Rabbits; Receptors, Serotonin; Serotonin Receptor Agonists; Structure-Activity Relationship; Swine; Tryptamines; Vasoconstriction	1993
Agonist activity of antimigraine drugs at recombinant human 5-HT1A receptors: potential implications for prophylactic and acute therapy. Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 355, Issue:6 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Benzopyrans; Binding, Competitive; Cell Membrane; Cricetinae; Dihydroergotamine; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Humans; In Vitro Techniques; Indoles; Lisuride; Methysergide; Migraine Disorders; Piperazines; Piperidines; Pizotyline; Propranolol; Propylamines; Protein Binding; Pyridines; Pyrimidines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Recombinant Proteins; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sumatriptan; Tryptamines	1997
Inhibition of noradrenaline release via presynaptic 5-HT1D alpha receptors in human atrium. Naunyn-Schmiedeberg's archives of pharmacology, 1996, Volume: 353, Issue:3 Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic Uptake Inhibitors; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cisapride; Corticosterone; Desipramine; Heart Atria; Humans; Indoles; Ketanserin; Male; Middle Aged; Norepinephrine; Oxadiazoles; Piperidines; Receptors, Presynaptic; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sumatriptan; Tritium; Tryptamines	1996
Evidence for presynaptic location of inhibitory 5-HT1D beta-like autoreceptors in the guinea-pig brain cortex. Naunyn-Schmiedeberg's archives of pharmacology, 1996, Volume: 353, Issue:3 Topics: Animals; Autoreceptors; Binding, Competitive; Cerebral Cortex; Guinea Pigs; Humans; Indoles; Ketanserin; Male; Methiothepin; Oxadiazoles; Oxymetazoline; Potassium; Radioligand Assay; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship; Sumatriptan; Synaptosomes; Tritium; Tryptamines	1996
Serotonin 5-HT(1B/1D) agonist-stimulated [(35)S]GTPgammaS binding in rat and guinea pig striatal membranes. Brain research, 1999, Jul-31, Volume: 836, Issue:1-2 Topics: Animals; Corpus Striatum; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guinea Pigs; Male; Membranes; Oxadiazoles; Pyridines; Pyrroles; Radioligand Assay; Rats; Serotonin; Serotonin Receptor Agonists; Stimulation, Chemical; Sulfur Radioisotopes; Tryptamines	1999
Involvement of 5-HT1B receptors in collar-induced hypersensitivity to 5-hydroxytryptamine of the rabbit carotid artery. British journal of pharmacology, 1999, Volume: 127, Issue:6 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Braces; Carotid Arteries; Dose-Response Relationship, Drug; Hypersensitivity; In Vitro Techniques; Ketanserin; Male; Methysergide; Oxadiazoles; Piperazines; Potassium Chloride; Rabbits; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Ritanserin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiperone; Sumatriptan; Tryptamines; Vasoconstriction	1999
Effect of 5-hydroxytryptamine on neurogenic vasoconstriction in the isolated, autoperfused hindquarters of the rat. Clinical and experimental pharmacology & physiology, 2005, Volume: 32, Issue:10 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Biguanides; Biphenyl Compounds; Dose-Response Relationship, Drug; Electric Stimulation; Hindlimb; In Vitro Techniques; Infusions, Intravenous; Male; Methiothepin; Oxadiazoles; Perfusion; Piperazines; Pressure; Quinoxalines; Rats; Rats, Wistar; Ritanserin; Serotonin; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Agonists; Serotonin 5-HT3 Receptor Agonists; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists; Tryptamines; Vasoconstriction	2005
Diabetes-induced changes in 5-hydroxytryptamine modulation of vagally-induced bradycardia in rat heart. Clinical and experimental pharmacology & physiology, 2007, Volume: 34, Issue:11 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Animals; Biphenyl Compounds; Blood Glucose; Bradycardia; Cholinergic Agents; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Electric Stimulation; Ergolines; Heart; Heart Rate; Injections, Intravenous; Male; Methiothepin; Oxadiazoles; Piperazines; Pyridines; Rats; Rats, Wistar; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tryptamines; Vagus Nerve	2007
Serotonin modulates glutamatergic transmission in the rat olfactory tubercle. The European journal of neuroscience, 2010, Volume: 31, Issue:4 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Citalopram; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Male; Olfactory Pathways; Oxadiazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists; Synaptic Transmission; Tryptamines	2010
5-HT1D receptor inhibits renal sympathetic neurotransmission by nitric oxide pathway in anesthetized rats. Vascular pharmacology, 2015, Volume: 72 Topics: Animals; Blood Pressure; Heart Rate; Kidney; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT1D; Receptors, Serotonin; Serotonin; Serotonin 5-HT1 Receptor Antagonists; Sympathetic Nervous System; Synaptic Transmission; Tryptamines	2015