Compounds > l 694,458
Page last updated: 2024-09-05

l 694,458 and tamoxifen

l 694,458 has been researched along with tamoxifen in 6 studies

Compound Research Comparison

Studies
(l 694,458)		Trials
(l 694,458)		Recent Studies (post-2010)
(l 694,458)		Studies
(tamoxifen)		Trials
(tamoxifen)		Recent Studies (post-2010) (tamoxifen)
2901020,6302,2276,256

Protein Interaction Comparison

ProteinTaxonomyl 694,458 (IC50)tamoxifen (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.46
Serine/threonine-protein kinase D3Homo sapiens (human)1
Bile salt export pumpHomo sapiens (human)10
Epidermal growth factor receptorHomo sapiens (human)3.553
Estrogen receptorHomo sapiens (human)0.9266
Receptor tyrosine-protein kinase erbB-2Homo sapiens (human)2.949
Protein kinase C gamma typeHomo sapiens (human)1
Protein kinase C beta typeHomo sapiens (human)1
Tyrosine-protein kinase LckHomo sapiens (human)8.033
Tyrosine-protein kinase FynHomo sapiens (human)1.195
Progesterone receptorHomo sapiens (human)0.1288
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)1.472
Muscarinic acetylcholine receptor M2Homo sapiens (human)7.793
Muscarinic acetylcholine receptor M4Homo sapiens (human)4.817
ATP-dependent translocase ABCB1Homo sapiens (human)6.4
Muscarinic acetylcholine receptor M5Homo sapiens (human)2.585
Alpha-2A adrenergic receptorHomo sapiens (human)1.935
Adenosine receptor A3Homo sapiens (human)3.701
Muscarinic acetylcholine receptor M1Homo sapiens (human)2.829
Steroid hormone receptor ERR1Homo sapiens (human)0.2
Angiotensin-converting enzymeOryctolagus cuniculus (rabbit)0.967
Beta-3 adrenergic receptorHomo sapiens (human)7.703
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)3.701
Protein kinase C alpha typeHomo sapiens (human)1
Alpha-2B adrenergic receptorHomo sapiens (human)3.518
Muscarinic acetylcholine receptor M3Homo sapiens (human)2.974
Substance-K receptorHomo sapiens (human)3.67
D(1A) dopamine receptorHomo sapiens (human)8.502
Prostaglandin G/H synthase 1Homo sapiens (human)4.391
Sodium-dependent noradrenaline transporter Homo sapiens (human)1.472
Thromboxane-A synthase Homo sapiens (human)0.916
Protein kinase C eta typeHomo sapiens (human)1
Histamine H2 receptorHomo sapiens (human)9.396
Alpha-1D adrenergic receptorHomo sapiens (human)4.982
5-hydroxytryptamine receptor 2AHomo sapiens (human)4.801
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.46
Adenosine receptor A2aHomo sapiens (human)7.099
Sodium-dependent serotonin transporterHomo sapiens (human)2.334
D(3) dopamine receptorHomo sapiens (human)1.072
5-hydroxytryptamine receptor 2BHomo sapiens (human)2.084
Protein kinase C iota typeHomo sapiens (human)1
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)3.701
5-hydroxytryptamine receptor 6Homo sapiens (human)2.679
Estrogen-related receptor gammaHomo sapiens (human)0.0622
Sodium-dependent dopamine transporter Homo sapiens (human)1.841
Protein kinase C epsilon typeHomo sapiens (human)1
Protein kinase C theta typeHomo sapiens (human)1
Protein kinase C zeta typeHomo sapiens (human)1
Protein kinase C delta typeHomo sapiens (human)1
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)1.2759
Platelet-activating factor acetylhydrolaseHomo sapiens (human)0.904
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomeraseHomo sapiens (human)0.012
Serine/threonine-protein kinase D1Homo sapiens (human)1
Nuclear receptor subfamily 3 group C member 3 Bos taurus (cattle)0.967
Estrogen receptor betaHomo sapiens (human)0.7809
Sigma non-opioid intracellular receptor 1Homo sapiens (human)0.021
7-dehydrocholesterol reductaseHomo sapiens (human)0.012

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's2 (33.33)24.3611
2020's2 (33.33)2.80

Authors

AuthorsStudies
Dansette, PM; Fontana, E; Poli, SM1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Glen, RC; Lowe, R; Mitchell, JB1
Burclaff, J; Goldenring, JR; Liu, D; Mills, JC; Osaki, LH1
Fujiwara, H; Furukawa, T; Hata, M; Hayakawa, Y; Hayata, Y; Hirata, Y; Kinoshita, H; Koike, K; Kon, S; Konishi, M; Kurokawa, K; Muranishi, Y; Nakagawa, H; Oya, Y; Tateishi, K; Tomita, H; Tsuboi, M; Wang, TC; Worthley, DL1
Goldenring, JR; Lapierre, LA; Manning, EH; Mills, JC1

Reviews

1 review(s) available for l 694,458 and tamoxifen

ArticleYear
Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity.
    Current drug metabolism, 2005, Volume: 6, Issue:5

    Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Isoenzymes; Structure-Activity Relationship; Terminology as Topic

2005

Other Studies

5 other study(ies) available for l 694,458 and tamoxifen

ArticleYear
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Targeted Apoptosis of Parietal Cells Is Insufficient to Induce Metaplasia in Stomach.
    Gastroenterology, 2017, Volume: 152, Issue:4

    Topics: Animals; Apoptosis; Atrophy; Azetidines; Cell Proliferation; Cellular Reprogramming; Chief Cells, Gastric; Diphtheria Toxin; Heparin-binding EGF-like Growth Factor; Intercellular Signaling Peptides and Proteins; Intrinsic Factor; Metaplasia; Mice; Parietal Cells, Gastric; Peptides; Piperazines; Plant Lectins; Stomach; Tamoxifen

2017
GPR30-Expressing Gastric Chief Cells Do Not Dedifferentiate But Are Eliminated via PDK-Dependent Cell Competition During Development of Metaplasia.
    Gastroenterology, 2020, Volume: 158, Issue:6

    Topics: Animals; Azetidines; Cell Communication; Cell Differentiation; Cell Lineage; Chief Cells, Gastric; Dichloroacetic Acid; Disease Models, Animal; Gastric Mucosa; Helicobacter Infections; Helicobacter pylori; Humans; Intercellular Signaling Peptides and Proteins; Metaplasia; Mice; Mice, Knockout; Piperazines; Pyruvate Dehydrogenase Acetyl-Transferring Kinase; Receptors, Estrogen; Receptors, G-Protein-Coupled; Stem Cells; Tamoxifen

2020
Tamoxifen Acts as a Parietal Cell Protonophore.
    Cellular and molecular gastroenterology and hepatology, 2020, Volume: 10, Issue:3

    Topics: Animals; Atrophy; Azetidines; Cells, Cultured; Disease Models, Animal; Humans; Hydrogen-Ion Concentration; Metaplasia; Parietal Cells, Gastric; Piperazines; Precancerous Conditions; Primary Cell Culture; Protons; Rabbits; Tamoxifen

2020