l 687414 has been researched along with dizocilpine maleate in 7 studies
| Studies (l 687414) | Trials (l 687414) | Recent Studies (post-2010) (l 687414) | Studies (dizocilpine maleate) | Trials (dizocilpine maleate) | Recent Studies (post-2010) (dizocilpine maleate) |
|---|---|---|---|---|---|
| 13 | 0 | 4 | 7,741 | 9 | 1,449 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (85.71) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Millan, MJ; Seguin, L | 1 |
| Bristow, LJ; Hutson, PH; Leeson, PD; Rowley, M; Saywell, K; Singh, L; Tattersall, FD; Thorn, L; Tricklebank, MD; Williams, BJ | 1 |
| Hargreaves, RJ; Hill, RG; Rigby, M; Smith, D | 1 |
| Hill, RG; Tortella, FC | 1 |
| Hill, RG; Kemp, JA; Marshall, GR; Priestley, T | 1 |
| Boyce, S; Hill, RG; Mason, G; O'Donnell, R; Rigby, M; Rupniak, NM; Sirinathsinghji, D; Webb, JK; Wyatt, A | 1 |
| Elliot, J; Grimwood, S; Huscroft, I; Hutson, PH; Kennedy, J; Mohnen, K; Murray, F; Russell, MG | 1 |
7 other study(ies) available for l 687414 and dizocilpine maleate
| Article | Year |
|---|---|
Chemically-diverse ligands at the glycine B site coupled to N-methyl-D-aspartate (NMDA) receptors selectively block the late phase of formalin-induced pain in mice.
Topics: 2-Amino-5-phosphonovalerate; Acetates; Acetic Acid; Animals; Anticonvulsants; Cycloserine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Formaldehyde; Indoles; Ligands; Male; Mice; Mice, Inbred Strains; Motor Activity; Pain; Propionates; Pyrrolidinones; Quinolones; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate | 1994 |
The anticonvulsant and behavioural profile of L-687,414, a partial agonist acting at the glycine modulatory site on the N-methyl-D-aspartate (NMDA) receptor complex.
Topics: Animals; Anticonvulsants; Behavior, Animal; Dizocilpine Maleate; Dopamine; Male; Mice; Mice, Inbred DBA; Motor Activity; Phencyclidine; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate | 1994 |
Lack of effect of L-687,414 ((+)-cis-4-methyl-HA-966), an NMDA receptor antagonist acting at the glycine site, on cerebral glucose metabolism and cortical neuronal morphology.
Topics: Animals; Blood Glucose; Blood Pressure; Brain Chemistry; Cerebral Cortex; Deoxyglucose; Dizocilpine Maleate; Glucose; Glycine; Heart Rate; Hemodynamics; Male; Neurons; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1993 |
EEG seizure activity and behavioral neurotoxicity produced by (+)-MK801, but not the glycine site antagonist L-687,414, in the rat.
Topics: Animals; Behavior, Animal; Dizocilpine Maleate; Drug Evaluation, Preclinical; Electroencephalography; Evaluation Studies as Topic; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Male; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate | 1996 |
L-687,414, a low efficacy NMDA receptor glycine site partial agonist in vitro, does not prevent hippocampal LTP in vivo at plasma levels known to be neuroprotective.
Topics: Animals; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Membrane Potentials; Neuroprotective Agents; Patch-Clamp Techniques; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission | 1998 |
Selective NMDA NR2B antagonists induce antinociception without motor dysfunction: correlation with restricted localisation of NR2B subunit in dorsal horn.
Topics: Acetates; Amines; Animals; Anticonvulsants; Cyclohexanecarboxylic Acids; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Lamotrigine; Male; Motor Activity; Pain Measurement; Phenols; Piperidines; Pyrrolidinones; Rabbits; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Spinal Cord; Triazines | 1999 |
Modulation of [3H]MK-801 binding to NMDA receptors in vivo and in vitro.
Topics: Animals; Binding Sites; Binding, Competitive; Brain; Chromans; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Ketamine; Kinetics; Male; Membranes; Mice; Phencyclidine; Phenols; Piperazines; Piperidines; Pyrrolidinones; Quinolones; Radioligand Assay; Rats; Receptors, N-Methyl-D-Aspartate; Tritium | 2000 |