l 687384 has been researched along with alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol in 2 studies
| Studies (l 687384) | Trials (l 687384) | Recent Studies (post-2010) (l 687384) | Studies (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol) | Trials (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol) | Recent Studies (post-2010) (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol) |
|---|---|---|---|---|---|
| 19 | 0 | 10 | 90 | 1 | 2 |
| Protein | Taxonomy | l 687384 (IC50) | alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol (IC50) |
|---|---|---|---|
| Cytochrome P450 3A4 | Homo sapiens (human) | 0.83 | |
| Tryptophan 5-hydroxylase 1 | Rattus norvegicus (Norway rat) | 6.43 | |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 0.83 | |
| Alpha-1B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.8267 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.91 | |
| Alpha-1D adrenergic receptor | Rattus norvegicus (Norway rat) | 0.8267 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 1.5 | |
| 5-hydroxytryptamine receptor 1D | Rattus norvegicus (Norway rat) | 1.5 | |
| 5-hydroxytryptamine receptor 1F | Rattus norvegicus (Norway rat) | 1.5 | |
| Alpha-1A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.8267 | |
| D(2) dopamine receptor | Mus musculus (house mouse) | 2.431 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 6.9225 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 0.06 | |
| Sigma non-opioid intracellular receptor 1 | Rattus norvegicus (Norway rat) | 0.073 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Meier, E; Moltzen, EK; Perregaard, J; Sánchez, C | 1 |
| Meier, E; Moltzen, EK; Perregaard, J | 1 |
2 other study(ies) available for l 687384 and alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol
| Article | Year |
|---|---|
Sigma ligands with subnanomolar affinity and preference for the sigma 2 binding site. 1. 3-(omega-aminoalkyl)-1H-indoles.
Topics: Animals; Binding Sites; Indoles; Ligands; Male; Piperidines; Rats; Rats, Wistar; Receptors, sigma; Sensitivity and Specificity; Structure-Activity Relationship | 1995 |
Sigma ligands with subnanomolar affinity and preference for the sigma 2 binding site. 2. Spiro-joined benzofuran, isobenzofuran, and benzopyran piperidines.
Topics: Animals; Benzofurans; Benzopyrans; Binding Sites; Binding, Competitive; Brain; Male; Piperidines; Rats; Rats, Wistar; Receptors, sigma; Sensitivity and Specificity; Structure-Activity Relationship | 1995 |