l 680833 has been researched along with fibrinogen in 1 studies
*Fibrinogen: Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products. [MeSH]
*Fibrinogen: Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products. [MeSH]
| Studies (l 680833) | Trials (l 680833) | Recent Studies (post-2010) (l 680833) | Studies (fibrinogen) | Trials (fibrinogen) | Recent Studies (post-2010) (fibrinogen) |
|---|---|---|---|---|---|
| 5 | 0 | 0 | 34,477 | 1,707 | 7,083 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brause, K; Chandler, GO; Doherty, JB; Dorn, CP; Finke, PE; Hagmann, WK; Hale, JJ; Kissinger, AL; Shah, SK; Thompson, KR | 1 |
1 other study(ies) available for l 680833 and fibrinogen
| Article | Year |
|---|---|
Chemical, biochemical, pharmacokinetic, and biological properties of L-680,833: a potent, orally active monocyclic beta-lactam inhibitor of human polymorphonuclear leukocyte elastase.
Topics: Amino Acid Sequence; Animals; Anti-Bacterial Agents; beta-Lactams; Biological Availability; Calcimycin; Cricetinae; Fibrinogen; Hemorrhage; Humans; Lactams; Leukocyte Elastase; Lung Diseases; Macaca mulatta; Mice; Molecular Sequence Data; Molecular Structure; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Pancreatic Elastase; Peptide Fragments; Phenylacetates; Rats; Structure-Activity Relationship | 1993 |