Page last updated: 2024-09-05

l 659066 and isoflurane

l 659066 has been researched along with isoflurane in 17 studies

Compound Research Comparison

Studies
(l 659066)
Trials
(l 659066)
Recent Studies (post-2010)
(l 659066)
Studies
(isoflurane)
Trials
(isoflurane)
Recent Studies (post-2010) (isoflurane)
7940579,7232,1172,666

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's12 (70.59)24.3611
2020's5 (29.41)2.80

Authors

AuthorsStudies
Bennett, RC; Junnila, J; Raekallio, M; Restitutti, F; Salla, K; Vainio, O1
del Castillo, JR; Kaartinen, J; Raekallio, MR; Salla, K; Troncy, E; Vainio, OM1
de Vries, A; Mykkänen, AK; Pakkanen, SA; Raekallio, MR; Salla, KM; Scheinin, M; Vainio, OM; Vuorilehto, L1
Honkavaara, J; Ilkiw, JE; Pypendop, BH1
Honkavaara, J; Ilkiw, JE; Pypendop, BH; Siao, KT1
Bennett, RC; Kuusela, E; Raekallio, MR; Salla, KM; Scheinin, M; Tuns, CI; Vainio, OM1
Hopster, K; Kästner, SB; Raekallio, M; Rohn, K; Vainio, OM; Wittenberg-Voges, L1
Campoy, L; Gleed, RD; Honkavaara, J; Martin-Flores, M; Portela, DA; Sakai, DM1
Ahokoivu, H; Honkavaara, J; Pypendop, BH3
Ahokoivu, H; Honkavaara, J; Jaeger, AT; Pypendop, BH1
Al-Ramahi, D; Hautajärvi, HJ; Männikkö, S; Mykkänen, AK; Raekallio, MR; Scheinin, M; Tapio, HA; Vainio, O1
Hanifeh, M; Junnila, J; Määttä, M; Mykkänen, A; Raekallio, M; Rajamäki, MM; Rossi, H; Tapio, H1
Kästner, S; Kopp, V; Neudeck, S; Twele, L1
Kobluk, K; Pypendop, BH1
Honkavaara, J; Huuskonen, V; Pesonen, T; Raekallio, M; Restitutti, F; Vainio, O1

Trials

12 trial(s) available for l 659066 and isoflurane

ArticleYear
A comparison in dogs of medetomidine, with or without MK-467, and the combination acepromazine-butorphanol as premedication prior to anaesthesia induced by propofol and maintained with isoflurane.
    Veterinary anaesthesia and analgesia, 2014, Volume: 41, Issue:2

    Topics: Acepromazine; Anesthesia; Animals; Blood Pressure; Butorphanol; Cross-Over Studies; Dogs; Drug Therapy, Combination; Female; Isoflurane; Male; Medetomidine; Oxygen; Propofol; Quinolizines

2014
Haemodynamic interactions of medetomidine and the peripheral alpha-2 antagonist MK-467 during step infusions in isoflurane-anaesthetised dogs.
    Veterinary journal (London, England : 1997), 2014, Volume: 202, Issue:2

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Anesthetics, Inhalation; Animals; Cross-Over Studies; Dogs; Drug Combinations; Female; Hemodynamics; Infusions, Intravenous; Isoflurane; Male; Medetomidine; Quinolizines

2014
Detomidine and the combination of detomidine and MK-467, a peripheral alpha-2 adrenoceptor antagonist, as premedication in horses anaesthetized with isoflurane.
    Veterinary anaesthesia and analgesia, 2015, Volume: 42, Issue:5

    Topics: Adrenergic alpha-2 Receptor Antagonists; Anesthesia, Inhalation; Anesthetics, Intravenous; Animals; Arthroscopy; Cross-Over Studies; Female; Heart Rate; Horses; Imidazoles; Isoflurane; Male; Premedication; Quinolizines; Treatment Outcome

2015
Hemodynamic effects of dexmedetomidine, with and without MK-467, following intramuscular administration in cats anesthetized with isoflurane.
    Veterinary anaesthesia and analgesia, 2017, Volume: 44, Issue:5

    Topics: Adrenergic alpha-2 Receptor Antagonists; Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Blood Pressure; Cats; Cross-Over Studies; Deep Sedation; Dexmedetomidine; Hemodynamics; Hypnotics and Sedatives; Injections, Intramuscular; Isoflurane; Male; Quinolizines; Vascular Resistance

2017
Cardiovascular effects of premedication with medetomidine alone and in combination with MK-467 or glycopyrrolate in dogs subsequently anesthetized with isoflurane.
    American journal of veterinary research, 2017, Volume: 78, Issue:11

    Topics: Adjuvants, Anesthesia; Anesthesia; Animals; Blood Pressure; Cardiovascular System; Cross-Over Studies; Dexmedetomidine; Dogs; Female; Glycopyrrolate; Heart Rate; Hemodynamics; Hypnotics and Sedatives; Isoflurane; Ketamine; Male; Medetomidine; Premedication; Quinolizines

2017
Effect of dexmedetomidine and xylazine followed by MK-467 on gastrointestinal microperfusion in anaesthetized horses.
    Veterinary anaesthesia and analgesia, 2018, Volume: 45, Issue:2

    Topics: Adrenergic alpha-2 Receptor Agonists; Anesthesia; Anesthetics, Combined; Animals; Dexmedetomidine; Female; Gastrointestinal Tract; Horses; Isoflurane; Male; Microcirculation; Oxygen; Prospective Studies; Quinolizines; Xylazine

2018
Effects of dexmedetomidine, with or without vatinoxan (MK-467), on minimum alveolar concentration of isoflurane in cats.
    Veterinary anaesthesia and analgesia, 2019, Volume: 46, Issue:4

    Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Cats; Cross-Over Studies; Dexmedetomidine; Drug Interactions; Drug Therapy, Combination; Hypnotics and Sedatives; Isoflurane; Male; Pulmonary Alveoli; Quinolizines

2019
Pharmacokinetics of dexmedetomidine during administration of vatinoxan in male neutered cats anesthetized with isoflurane.
    Journal of veterinary pharmacology and therapeutics, 2020, Volume: 43, Issue:1

    Topics: Anesthesia; Anesthetics, Inhalation; Animals; Cats; Dexmedetomidine; Drug Interactions; Hypnotics and Sedatives; Isoflurane; Male; Quinolizines

2020
Cardiopulmonary effects of dexmedetomidine, with and without vatinoxan, in isoflurane-anesthetized cats.
    Veterinary anaesthesia and analgesia, 2019, Volume: 46, Issue:6

    Topics: Adrenergic alpha-2 Receptor Antagonists; Anesthetics, Inhalation; Animals; Blood Pressure; Cats; Cross-Over Studies; Dexmedetomidine; Dose-Response Relationship, Drug; Drug Interactions; Heart Rate; Hypnotics and Sedatives; Hypotension; Isoflurane; Male; Quinolizines; Vascular Resistance

2019
Pharmacodynamics and plasma concentrations of dexmedetomidine with or without vatinoxan as a constant-rate infusion in horses anaesthetized with isoflurane-A pilot study.
    Journal of veterinary pharmacology and therapeutics, 2021, Volume: 44, Issue:5

    Topics: Anesthetics, Inhalation; Animals; Dexmedetomidine; Horses; Isoflurane; Pilot Projects; Prospective Studies; Quinolizines

2021
Effects of dopamine, norepinephrine or phenylephrine on the prevention of hypotension in isoflurane-anesthetized cats administered vatinoxan or vatinoxan and dexmedetomidine.
    Veterinary anaesthesia and analgesia, 2022, Volume: 49, Issue:1

    Topics: Anesthetics, Inhalation; Animals; Blood Pressure; Dexmedetomidine; Dopamine; Heart Rate; Hypotension; Isoflurane; Male; Norepinephrine; Phenylephrine; Quinolizines

2022
Cardiovascular effects of dobutamine, norepinephrine and phenylephrine in isoflurane-anaesthetized dogs administered dexmedetomidine-vatinoxan.
    Veterinary anaesthesia and analgesia, 2022, Volume: 49, Issue:6

    Topics: Anesthetics, Inhalation; Animals; Blood Pressure; Dexmedetomidine; Dobutamine; Dog Diseases; Dogs; Hypotension; Isoflurane; Norepinephrine; Phenylephrine; Saline Solution

2022

Other Studies

5 other study(ies) available for l 659066 and isoflurane

ArticleYear
Cardiovascular effects of dexmedetomidine, with or without MK-467, following intravenous administration in cats.
    Veterinary anaesthesia and analgesia, 2017, Volume: 44, Issue:1

    Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-2 Receptor Antagonists; Anesthesia, Intravenous; Anesthetics, Inhalation; Animals; Blood Pressure; Cardiovascular System; Cats; Desflurane; Dexmedetomidine; Female; Heart Rate; Isoflurane; Prospective Studies; Quinolizines; Vasoconstriction

2017
Hemodynamic effects of MK-467 following intravenous administration to isoflurane-anesthetized cats concurrently receiving dexmedetomidine.
    American journal of veterinary research, 2018, Volume: 79, Issue:7

    Topics: Anesthetics, Inhalation; Animals; Arteries; Blood Pressure; Cats; Dexmedetomidine; Female; Heart Rate; Hemodynamics; Infusions, Intravenous; Isoflurane; Quinolizines; Vascular Resistance

2018
Effects of vatinoxan on cardiorespiratory function, fecal output and plasma drug concentrations in horses anesthetized with isoflurane and infusion of medetomidine.
    Veterinary journal (London, England : 1997), 2019, Volume: 251

    Topics: Adrenergic alpha-2 Receptor Antagonists; Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Blood Pressure; Cardiovascular Physiological Phenomena; Cross-Over Studies; Female; Gastrointestinal Motility; Heart Rate; Horses; Hypnotics and Sedatives; Isoflurane; Male; Medetomidine; Quinolizines

2019
Effects of general anaesthesia in dorsal recumbency with and without vatinoxan on bronchoalveolar lavage cytology of healthy horses.
    Veterinary journal (London, England : 1997), 2019, Volume: 251

    Topics: Anesthesia, General; Anesthetics, Inhalation; Animals; Bronchoalveolar Lavage Fluid; Cross-Over Studies; Horses; Hypnotics and Sedatives; Inflammation; Isoflurane; Medetomidine; Posture; Quinolizines; Serum Amyloid A Protein

2019
Pharmacokinetics of vatinoxan in male neutered cats anesthetized with isoflurane.
    Veterinary anaesthesia and analgesia, 2020, Volume: 47, Issue:1

    Topics: Anesthesia; Anesthetics, Inhalation; Animals; Cats; Infusions, Intravenous; Isoflurane; Male; Orchiectomy; Quinolizines

2020
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