l 656224 has been researched along with benzofurans in 8 studies
| Studies (l 656224) | Trials (l 656224) | Recent Studies (post-2010) (l 656224) | Studies (benzofurans) | Trials (benzofurans) | Recent Studies (post-2010) (benzofurans) |
|---|---|---|---|---|---|
| 8 | 0 | 0 | 13,293 | 451 | 4,970 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 6 (75.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anderson, CA; Antonello, JM; Clark, RL; Vetter, CM; Wise, LD | 1 |
| Falgueyret, JP; Gresser, MJ; Lau, CK; Riendeau, D; Rouzer, CA | 1 |
| Bach, T; Bélanger, PC; Dallob, AL; Denis, D; Dufresne, C; Guindon, Y; Lau, CK; Maycock, AL; Scheigetz, J; Williams, HW | 1 |
| Bach, T; Belanger, P; Dollob, AL; Dufresne, C; Ford-Hutchinson, AW; Gale, PH; Guindon, Y; Hopple, S; Lau, CK; Maycock, A | 1 |
| Rainsford, KD; Smith, F; Ying, C | 2 |
| Ben-Menahem, D; Naor, Z; Shraga-Levine, Z | 1 |
| Gyömber, E; Rainsford, KD; Szabo, S; Vattay, P | 1 |
8 other study(ies) available for l 656224 and benzofurans
| Article | Year |
|---|---|
Reversible effects of triamcinolone and lack of effects with aspirin or L-656,224 on external genitalia of male Sprague-Dawley rats exposed in utero.
Topics: Abnormalities, Drug-Induced; Animals; Arachidonic Acid; Aspirin; Benzofurans; Female; Fetal Death; Genitalia, Male; Gestational Age; Hypospadias; Male; Pregnancy; Rats; Rats, Inbred Strains; Triamcinolone; Weaning | 1991 |
Inhibition of human leukocyte 5-lipoxygenase by a 4-hydroxybenzofuran, L-656,224. Evidence for enzyme reduction and inhibitor degradation.
Topics: Adenosine Triphosphate; Alkylation; Arachidonate 5-Lipoxygenase; Benzofurans; Calcium; Humans; Leukocytes; Linoleic Acids; Lipid Peroxides; Lipoxygenase Inhibitors; Oxidation-Reduction; Peroxidases | 1991 |
Synthesis and structure-activity relationships of a novel class of 5-lipoxygenase inhibitors. 2-(Phenylmethyl)-4-hydroxy-3,5-dialkylbenzofurans: the development of L-656,224.
Topics: Adult; Animals; Arachidonate Lipoxygenases; Benzofurans; Bronchi; Chemical Phenomena; Chemistry; Constriction, Pathologic; Humans; Immunoglobulin E; Leukocytes; Leukotriene B4; Lipoxygenase Inhibitors; Molecular Structure; Neutrophils; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1989 |
L-656,224 (7-chloro-2-[(4-methoxyphenyl)methyl]-3- methyl-5-propyl-4-benzofuranol): a novel, selective, orally active 5-lipoxygenase inhibitor.
Topics: Animals; Arachidonate Lipoxygenases; Benzofurans; Blood Platelets; Catalase; Cattle; Cells, Cultured; Eating; Female; Glycine max; Humans; Leukocytes; Lipoxygenase Inhibitors; Neutrophils; Peroxidase; Prostaglandin-Endoperoxide Synthases; Rats; Saimiri; Species Specificity; Swine | 1987 |
Selective effects of some 5-lipoxygenase inhibitors on synovial interleukin-1 (IL-1) production compared with IL-1 synthesis inhibitors.
Topics: Arthritis; Benzofurans; Culture Media; Culture Techniques; Humans; Hydrocortisone; Indoles; Interleukin-1; Leukotriene Antagonists; Lipoxygenase Inhibitors; Quinolines; Synovial Membrane | 1993 |
Arachidonic acid and lipoxygenase products stimulate protein kinase C beta mRNA levels in pituitary alpha T3-1 cell line: role in gonadotropin-releasing hormone action.
Topics: Acetophenones; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Benzofurans; Cell Line; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Gonadotropin-Releasing Hormone; Hydroxyeicosatetraenoic Acids; Indomethacin; Kinetics; Leukotriene C4; Lipoxygenase; Lipoxygenase Inhibitors; Pituitary Gland; Protein Kinase C; Protein Kinase C beta; RNA, Messenger | 1996 |
Effects of 5-lipoxygenase inhibitors on interleukin production by human synovial tissues in organ culture: comparison with interleukin-1-synthesis inhibitors.
Topics: Animals; Benzofurans; Enzyme-Linked Immunosorbent Assay; Hip Joint; Humans; Hydroxyurea; Indoles; Interleukin-1; Knee Joint; Lipoxygenase Inhibitors; Naphthalenes; Organ Culture Techniques; Oxindoles; Pyrazoles; Quinolines; Structure-Activity Relationship; Swine; Synovial Membrane; Tarsus, Animal; Thiazoles; Thiophenes | 1996 |
Effect of lipoxygenase inhibitors and leukotriene antagonists on acute and chronic gastric haemorrhagic mucosal lesions in ulcer models in the rat.
Topics: Animals; Aspirin; Benzofurans; Ethanol; Female; Gastritis; Indomethacin; Iodoacetamide; Leukotriene D4; Leukotrienes; Lipoxygenase Inhibitors; Peptic Ulcer Hemorrhage; Phenylbutyrates; Propionates; Quinolines; Rats; Rats, Sprague-Dawley; Stomach Ulcer | 1996 |