Page last updated: 2024-09-03

l 655240 and indomethacin

l 655240 has been researched along with indomethacin in 5 studies

Compound Research Comparison

Studies
(l 655240)
Trials
(l 655240)
Recent Studies (post-2010)
(l 655240)
Studies
(indomethacin)
Trials
(indomethacin)
Recent Studies (post-2010) (indomethacin)
260429,5271,8383,396

Protein Interaction Comparison

ProteinTaxonomyl 655240 (IC50)indomethacin (IC50)
Chain A, membrane-associated prostaglandin E synthase-2Macaca fascicularis (crab-eating macaque)1000
Prostaglandin-H2 D-isomeraseMus musculus (house mouse)1.1
Multidrug resistance-associated protein 4Homo sapiens (human)5.8
Prostaglandin G/H synthase 1 Bos taurus (cattle)0.9994
Prostaglandin G/H synthase 2 Bos taurus (cattle)0.7764
Cytochrome c oxidase subunit 2Homo sapiens (human)0.34
Prostaglandin G/H synthase 1Ovis aries (sheep)0.5605
Neuronal acetylcholine receptor subunit alpha-4Rattus norvegicus (Norway rat)0.004
Interleukin-8Homo sapiens (human)0.05
Neuronal acetylcholine receptor subunit beta-2Rattus norvegicus (Norway rat)0.004
Aldo-keto reductase family 1 member B1Homo sapiens (human)6
Aldo-keto reductase family 1 member B1Bos taurus (cattle)5
Prostaglandin G/H synthase 1Mus musculus (house mouse)0.011
Prostaglandin G/H synthase 1Homo sapiens (human)0.4848
Sodium- and chloride-dependent GABA transporter 1Rattus norvegicus (Norway rat)0.2
Thromboxane-A synthase Homo sapiens (human)0.1
Indoleamine 2,3-dioxygenase 1Mus musculus (house mouse)0.082
Nitric oxide synthase, inducibleMus musculus (house mouse)4.5
Substance-P receptorCavia porcellus (domestic guinea pig)5.7
Sodium- and chloride-dependent GABA transporter 2Rattus norvegicus (Norway rat)0.2
Sodium- and chloride-dependent GABA transporter 3Rattus norvegicus (Norway rat)0.2
Prostaglandin G/H synthase 2Homo sapiens (human)1.5128
Prostaglandin G/H synthase 2 Rattus norvegicus (Norway rat)0.5504
Aldo-keto reductase family 1 member C3Homo sapiens (human)3.4486
Sodium- and chloride-dependent betaine transporterRattus norvegicus (Norway rat)0.2
C-X-C chemokine receptor type 3Homo sapiens (human)0.05
Aldo-keto reductase family 1 member C2 Homo sapiens (human)8.97
Prostaglandin G/H synthase 2Ovis aries (sheep)3.4647
Prostaglandin G/H synthase 2Mus musculus (house mouse)0.4233
Solute carrier family 22 member 6Homo sapiens (human)3
Sigma intracellular receptor 2Rattus norvegicus (Norway rat)0.49
Rho-associated protein kinase 2Rattus norvegicus (Norway rat)7.7
Prostaglandin G/H synthase 1 Rattus norvegicus (Norway rat)0.5461
P2Y purinoceptor 12Rattus norvegicus (Norway rat)0.96

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's3 (60.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Calvo, IF; da Rocha, FA; de Falco, V; Fernandes, AJ; Jancar, S; Sirois, P1
Bryan, AC; Burger, R; Fung, D1
Braquet, P; Jancar, S; Lauzière, M; Sirois, P; Thériault, P1
Moreira, E; Weinberg, J; Weinberg, ML1

Other Studies

5 other study(ies) available for l 655240 and indomethacin

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Mechanisms of thrombocytopenia in the acute phase of antigen-induced arthritis in rabbits.
    Prostaglandins, 1991, Volume: 42, Issue:6

    Topics: Animals; Arthritis, Experimental; Diterpenes; Econazole; Female; Ginkgolides; Indoles; Indomethacin; Lactones; Male; Platelet Activating Factor; Rabbits; Synovial Fluid; Thrombocytopenia; Thromboxane A2; Thromboxane B2

1991
Lung injury in a surfactant-deficient lung is modified by indomethacin.
    Journal of applied physiology (Bethesda, Md. : 1985), 1990, Volume: 69, Issue:6

    Topics: Animals; Hypertension, Pulmonary; Indoles; Indomethacin; Leukocyte Count; Lung; Neutrophils; Platelet Count; Pulmonary Surfactants; Rabbits; Therapeutic Irrigation; Thromboxane A2

1990
Paf-induced release of spasmogens from guinea-pig lungs.
    British journal of pharmacology, 1989, Volume: 96, Issue:1

    Topics: Animals; Aspirin; Bronchi; Chromones; Diterpenes; Ginkgolides; Guinea Pigs; In Vitro Techniques; Indoles; Indomethacin; Lactones; Leukotriene B4; Lung; Masoprocol; Muscle Contraction; Muscle, Smooth; Platelet Activating Factor; SRS-A; Trachea

1989
Arachidonic acid products-mediated contraction induced by bradykinin in relaxed mesenteric arterial rings from Holtzman rats.
    European journal of pharmacology, 1997, Feb-12, Volume: 320, Issue:2-3

    Topics: Animals; Arachidonic Acid; Bradykinin; Bradykinin Receptor Antagonists; Dinoprost; Endothelium, Vascular; Enzyme Inhibitors; Imidazoles; In Vitro Techniques; Indoles; Indomethacin; Mesenteric Artery, Superior; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Prostaglandin Antagonists; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Bradykinin

1997