Page last updated: 2024-09-03

l 651392 and leukotriene b4

l 651392 has been researched along with leukotriene b4 in 8 studies

Compound Research Comparison

Studies
(l 651392)
Trials
(l 651392)
Recent Studies (post-2010)
(l 651392)
Studies
(leukotriene b4)
Trials
(leukotriene b4)
Recent Studies (post-2010) (leukotriene b4)
31005,886232717

Protein Interaction Comparison

ProteinTaxonomyl 651392 (IC50)leukotriene b4 (IC50)
Leukotriene B4 receptor 1Homo sapiens (human)0.0019

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19905 (62.50)18.7374
1990's3 (37.50)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Leikauf, GD1
Beck, PL; MacNaughton, WK; Morris, GP; Wallace, JL1
Chan, CC; Dubois, L; Young, V1
Atkinson, JG; BĂ©langer, PC; Dallob, A; DeSousa, D; Dougherty, H; Egan, R; Ford-Hutchinson, AW; Girard, Y; Guindon, Y; Maycock, A1
Charleson, S; Ford-Hutchinson, AW; Garceau, D1
Blair, IA; Butterfield, MJ; Christman, BW; Coggeshall, JW; Lefferts, PL; Serafin, WE; Snapper, JR1
Becker, I; Huber, W; Peskar, BM; Schenck, U; Schepp, W; Trautmann, M1
Christman, BW; Kuratomi, Y; Lefferts, PL; Mueller, RA; Parker, RE; Smith, WG; Snapper, JR1

Other Studies

8 other study(ies) available for l 651392 and leukotriene b4

ArticleYear
Mechanisms of aldehyde-induced bronchial reactivity: role of airway epithelium.
    Research report (Health Effects Institute), 1992, Issue:49

    Topics: Acetylcholine; Acrolein; Air Pollutants; Airway Resistance; Animals; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Epithelium; Epoprostenol; Formaldehyde; Guinea Pigs; Hyperplasia; Inflammation; Leukocyte Count; Leukotriene B4; Lipoxygenase Inhibitors; Neutrophils; Phenothiazines; Phenylbutyrates; Prostaglandins F; SRS-A; Thromboxane B2; Time Factors

1992
Inhibition of leukotriene synthesis markedly accelerates healing in a rat model of inflammatory bowel disease.
    Gastroenterology, 1989, Volume: 96, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Aminosalicylic Acids; Animals; Chronic Disease; Colitis; Colon; Leukotriene B4; Lipoxygenase Inhibitors; Male; Mesalamine; Peroxidase; Phenothiazines; Prostaglandins E; Rats; Rats, Inbred Strains; Rioprostil

1989
Effects of two novel inhibitors of 5-lipoxygenase, L-651,392 and L-651,896, in a guinea-pig model of epidermal hyperproliferation.
    European journal of pharmacology, 1987, Jul-02, Volume: 139, Issue:1

    Topics: Animals; Arachidonate Lipoxygenases; Benzofurans; Calcimycin; Cell Division; Dinoprostone; DNA; Epidermal Cells; Female; Guinea Pigs; In Vitro Techniques; Leukotriene B4; Lipoxygenase Inhibitors; Male; Phenothiazines; Prostaglandins E

1987
L-651,392: a novel, potent and selective 5-lipoxygenase inhibitor.
    Advances in prostaglandin, thromboxane, and leukotriene research, 1987, Volume: 17A

    Topics: Animals; Arachidonate Lipoxygenases; Bronchi; Capillary Permeability; Humans; In Vitro Techniques; Leukotriene B4; Lipoxygenase Inhibitors; Phenothiazines; SRS-A

1987
5-Lipoxygenase inhibitors and allergic conjunctivitis reactions in the guinea-pig.
    European journal of pharmacology, 1987, Nov-03, Volume: 143, Issue:1

    Topics: Animals; Arachidonate Lipoxygenases; Benzofurans; Calcimycin; Capillary Permeability; Conjunctivitis, Allergic; Guinea Pigs; Leukotriene B4; Lipoxygenase Inhibitors; Male; Phenothiazines; Pyrilamine; SRS-A

1987
Effect of inhibition of 5-lipoxygenase metabolism of arachidonic acid on response to endotoxemia in sheep.
    Journal of applied physiology (Bethesda, Md. : 1985), 1988, Volume: 65, Issue:3

    Topics: Animals; Arachidonate 5-Lipoxygenase; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Endotoxins; Female; Granulocytes; In Vitro Techniques; Leukotriene B4; Lipoxygenase Inhibitors; Lung; Lymph; Male; Phenothiazines; Pulmonary Circulation; Respiratory Distress Syndrome; Sheep; Toxemia

1988
Leukotriene B4 and C4 production in isolated rat gastric mucosal cells.
    The American journal of physiology, 1993, Volume: 265, Issue:6 Pt 1

    Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Bucladesine; Calcimycin; Cell Separation; Colforsin; Diglycerides; Female; Gastric Mucosa; Histamine; In Vitro Techniques; Interleukin-1; Interleukin-2; Kinetics; Leukotriene B4; Leukotriene C4; Lipoxygenase Inhibitors; N-Formylmethionine Leucyl-Phenylalanine; Pentagastrin; Phenothiazines; Platelet Activating Factor; Rats; Rats, Wistar; Tetradecanoylphorbol Acetate

1993
Effect of a 5-lipoxygenase inhibitor on endotoxin-induced pulmonary dysfunction in awake sheep.
    Journal of applied physiology (Bethesda, Md. : 1985), 1993, Volume: 74, Issue:2

    Topics: 6-Ketoprostaglandin F1 alpha; Acetates; Animals; Arachidonate 5-Lipoxygenase; Blood Pressure; Dinoprostone; Endotoxins; Female; Gas Chromatography-Mass Spectrometry; Granulocytes; Hemodynamics; Leukotriene B4; Lipoxygenase Inhibitors; Lung Diseases; Lymphatic System; Male; Phenols; Phenothiazines; Respiratory Mechanics; Sheep; Superoxides; Thromboxane B2

1993