Page last updated: 2024-09-03

l 649923 and histamine

l 649923 has been researched along with histamine in 4 studies

Compound Research Comparison

Studies (l 649923)	Trials (l 649923)	Recent Studies (post-2010) (l 649923)	Studies (histamine)	Trials (histamine)	Recent Studies (post-2010) (histamine)
36	4	0	37,718	1,372	3,457

Protein Interaction Comparison

Protein	Taxonomy	l 649923 (IC50)	histamine (IC50)
Histamine H1 receptor	Rattus norvegicus (Norway rat)		0.1585
Histamine H1 receptor	Homo sapiens (human)		0.1585

Research

Studies (4)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (100.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Barnes, NC; Costello, JF; Piper, PJ	1
Barnes, N; Costello, J; Piper, PJ	1
Ford-Hutchinson, AW; Garceau, D	1
Bell, RL; Regal, JF	1

Trials

1 trial(s) available for l 649923 and histamine

Article	Year
The effect of an oral leukotriene antagonist L-649,923 on histamine and leukotriene D4-induced bronchoconstriction in normal man. The Journal of allergy and clinical immunology, 1987, Volume: 79, Issue:5 Topics: Adult; Bronchial Spasm; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Histamine; Humans; Male; Phenylbutyrates; Random Allocation; Respiratory Function Tests; SRS-A	1987

Article

Year

The effect of an oral leukotriene antagonist L-649,923 on histamine and leukotriene D4-induced bronchoconstriction in normal man.

The Journal of allergy and clinical immunology, 1987, Volume: 79, Issue:5

Topics: Adult; Bronchial Spasm; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Histamine; Humans; Male; Phenylbutyrates; Random Allocation; Respiratory Function Tests; SRS-A

1987

Other Studies

3 other study(ies) available for l 649923 and histamine

Article	Year
Studies of an orally active leukotriene antagonist L-649,923 in normal man. Advances in prostaglandin, thromboxane, and leukotriene research, 1987, Volume: 17B Topics: Administration, Oral; Adult; Bronchi; Drug Evaluation; Histamine; Humans; Male; Phenylbutyrates; SRS-A	1987
The role of leukotriene D4 as a mediator of allergic conjunctivitis in the guinea-pig. European journal of pharmacology, 1987, Feb-24, Volume: 134, Issue:3 Topics: Animals; Capillary Permeability; Conjunctivitis, Allergic; Guinea Pigs; Histamine; Indomethacin; Keto Acids; Male; Phenylbutyrates; SRS-A; Sulfones	1987
Mediators of C5a-induced bronchoconstriction in the guinea pig. International archives of allergy and applied immunology, 1987, Volume: 84, Issue:4 Topics: Acetylcholine; Animals; Atropine; Bronchi; Bronchial Spasm; Chromones; Complement C5; Guinea Pigs; Histamine; Indomethacin; Male; Phenylbutyrates; Pyrilamine; SRS-A	1987