l 649923 and histamine
l 649923 has been researched along with histamine in 4 studies
Compound Research Comparison
| Studies (l 649923) | Trials (l 649923) | Recent Studies (post-2010) (l 649923) | Studies (histamine) | Trials (histamine) | Recent Studies (post-2010) (histamine) |
|---|---|---|---|---|---|
| 36 | 4 | 0 | 37,718 | 1,372 | 3,457 |
Protein Interaction Comparison
| Protein | Taxonomy | l 649923 (IC50) | histamine (IC50) |
|---|---|---|---|
| Histamine H1 receptor | Rattus norvegicus (Norway rat) | 0.1585 | |
| Histamine H1 receptor | Homo sapiens (human) | 0.1585 |
Research
Studies (4)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Barnes, NC; Costello, JF; Piper, PJ | 1 |
| Barnes, N; Costello, J; Piper, PJ | 1 |
| Ford-Hutchinson, AW; Garceau, D | 1 |
| Bell, RL; Regal, JF | 1 |
Trials
1 trial(s) available for l 649923 and histamine
| Article | Year |
|---|---|
The effect of an oral leukotriene antagonist L-649,923 on histamine and leukotriene D4-induced bronchoconstriction in normal man.
Topics: Adult; Bronchial Spasm; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Histamine; Humans; Male; Phenylbutyrates; Random Allocation; Respiratory Function Tests; SRS-A | 1987 |
Other Studies
3 other study(ies) available for l 649923 and histamine
| Article | Year |
|---|---|
Studies of an orally active leukotriene antagonist L-649,923 in normal man.
Topics: Administration, Oral; Adult; Bronchi; Drug Evaluation; Histamine; Humans; Male; Phenylbutyrates; SRS-A | 1987 |
The role of leukotriene D4 as a mediator of allergic conjunctivitis in the guinea-pig.
Topics: Animals; Capillary Permeability; Conjunctivitis, Allergic; Guinea Pigs; Histamine; Indomethacin; Keto Acids; Male; Phenylbutyrates; SRS-A; Sulfones | 1987 |
Mediators of C5a-induced bronchoconstriction in the guinea pig.
Topics: Acetylcholine; Animals; Atropine; Bronchi; Bronchial Spasm; Chromones; Complement C5; Guinea Pigs; Histamine; Indomethacin; Male; Phenylbutyrates; Pyrilamine; SRS-A | 1987 |