Compounds > l 645151
Page last updated: 2024-09-04

l 645151 and ethoxzolamide

l 645151 has been researched along with ethoxzolamide in 5 studies

Compound Research Comparison

Studies
(l 645151)		Trials
(l 645151)		Recent Studies (post-2010)
(l 645151)		Studies
(ethoxzolamide)		Trials
(ethoxzolamide)		Recent Studies (post-2010) (ethoxzolamide)
700357394

Protein Interaction Comparison

ProteinTaxonomyl 645151 (IC50)ethoxzolamide (IC50)
Carbonic anhydrase 1Homo sapiens (human)0.0417
Carbonic anhydrase 2Homo sapiens (human)0.0023
Carbonic anhydrase 9Homo sapiens (human)0.0006

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Anderson, PS; Baldwin, JJ; Best, DB; Christy, ME; Freedman, MB; Gautheron, P; Graham, SL; Habecker, CN; Hoffman, JM; Shepard, KL1
Bicking, JB; Brown, SL; deSolms, SJ; Fishman, DR; Gautheron, PD; Graham, SL; Hoffman, JM; Larson, RD; Schwam, H; Woltersdorf, OW1
Baldwin, JJ; Christy, ME; Freedman, MB; Habecker, CN; Lyle, PA; Ponticello, GS; Randall, WC; Schwam, H; Varga, SL1
Gros, G; Papadopoulos, S; Wetzel, P1
Gros, G; Kleinke, T; Papadopoulos, S; Wetzel, P1

Other Studies

5 other study(ies) available for l 645151 and ethoxzolamide

ArticleYear
Topically active carbonic anhydrase inhibitors. 2. Benzo[b]thiophenesulfonamide derivatives with ocular hypotensive activity.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:12

    Topics: Animals; Carbonic Anhydrase Inhibitors; Chemical Phenomena; Chemistry; Glaucoma; Guinea Pigs; Intraocular Pressure; Ocular Hypertension; Rabbits; Skin; Sulfonamides; Thiophenes

1989
Topically active carbonic anhydrase inhibitors. 1. O-acyl derivatives of 6-hydroxybenzothiazole-2-sulfonamide.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:11

    Topics: Animals; Benzothiazoles; Carbonic Anhydrase Inhibitors; Chemical Phenomena; Chemistry; Cornea; Ethoxzolamide; Guinea Pigs; Humans; Intraocular Pressure; Ophthalmic Solutions; Prodrugs; Rabbits; Thiazoles

1989
Thienothiopyran-2-sulfonamides: a novel class of water-soluble carbonic anhydrase inhibitors.
    Journal of medicinal chemistry, 1987, Volume: 30, Issue:4

    Topics: Carbonic Anhydrase Inhibitors; Chemical Phenomena; Chemistry; Erythrocytes; Glaucoma; Heterocyclic Compounds; Humans; Solubility; Structure-Activity Relationship; Sulfonamides; Water

1987
Inhibition of muscle carbonic anhydrase increases rise and relaxation times of twitches in rat skeletal muscle fibres.
    Pflugers Archiv : European journal of physiology, 2002, Volume: 443, Issue:5-6

    Topics: Acetazolamide; Animals; Benzolamide; Benzothiazoles; Bicarbonates; Buffers; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Ethoxzolamide; Female; HEPES; Hydrogen-Ion Concentration; Muscle Contraction; Muscle Fibers, Skeletal; Muscle Relaxation; Muscle, Skeletal; Rats; Rats, Inbred WF; Sarcoplasmic Reticulum; Thiadiazoles; Thiazoles

2002
Inhibition of muscle carbonic anhydrase slows the Ca(2+) transient in rat skeletal muscle fibers.
    American journal of physiology. Cell physiology, 2002, Volume: 283, Issue:4

    Topics: Acetazolamide; Action Potentials; Adenosine Triphosphatases; Animals; Benzothiazoles; Calcium; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Chelating Agents; Dose-Response Relationship, Drug; Enzyme Activation; Ethoxzolamide; Female; Fura-2; In Vitro Techniques; Ion Transport; Isometric Contraction; Muscle Contraction; Muscle Fibers, Skeletal; Muscle, Skeletal; Rats; Sarcoplasmic Reticulum; Thiadiazoles; Thiazoles; Time Factors

2002