l 645151 has been researched along with acetazolamide in 4 studies
| Studies (l 645151) | Trials (l 645151) | Recent Studies (post-2010) (l 645151) | Studies (acetazolamide) | Trials (acetazolamide) | Recent Studies (post-2010) (acetazolamide) |
|---|---|---|---|---|---|
| 7 | 0 | 0 | 7,604 | 495 | 1,521 |
| Protein | Taxonomy | l 645151 (IC50) | acetazolamide (IC50) |
|---|---|---|---|
| Chain A, Class Iii Chitinase Chia1 | Aspergillus fumigatus A1163 | 164 | |
| Carbonic anhydrase 12 | Homo sapiens (human) | 0.3178 | |
| Renin | Homo sapiens (human) | 8.2 | |
| Carbonic anhydrase 1 | Homo sapiens (human) | 2.3173 | |
| Carbonic anhydrase 2 | Homo sapiens (human) | 1.2619 | |
| Carbonic anhydrase 2 | Bos taurus (cattle) | 0.7 | |
| Carbonic anhydrase 3 | Homo sapiens (human) | 1.95 | |
| Cathepsin B | Bos taurus (cattle) | 0.02 | |
| Steryl-sulfatase | Homo sapiens (human) | 0.025 | |
| Carbonic anhydrase 4 | Homo sapiens (human) | 0.1216 | |
| Carbonic anhydrase 6 | Homo sapiens (human) | 0.2925 | |
| Carbonic anhydrase 5A, mitochondrial | Homo sapiens (human) | 0.1763 | |
| Carbonic anhydrase 7 | Homo sapiens (human) | 1.1737 | |
| Carbonic anhydrase 9 | Homo sapiens (human) | 0.464 | |
| Renin | Macaca mulatta (Rhesus monkey) | 8.2 | |
| Carbonic anhydrase 13 | Homo sapiens (human) | 0.23 | |
| Carbonic anhydrase 4 | Bos taurus (cattle) | 0.07 | |
| Carbonic anhydrase 13 | Mus musculus (house mouse) | 0.77 | |
| Carbonic anhydrase 14 | Homo sapiens (human) | 0.183 | |
| Carbonic anhydrase 5B, mitochondrial | Homo sapiens (human) | 0.23 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Anderson, PS; Baldwin, JJ; Best, DB; Christy, ME; Freedman, MB; Gautheron, P; Graham, SL; Habecker, CN; Hoffman, JM; Shepard, KL | 1 |
| Bicking, JB; Brown, SL; deSolms, SJ; Fishman, DR; Gautheron, PD; Graham, SL; Hoffman, JM; Larson, RD; Schwam, H; Woltersdorf, OW | 1 |
| Gros, G; Papadopoulos, S; Wetzel, P | 1 |
| Gros, G; Kleinke, T; Papadopoulos, S; Wetzel, P | 1 |
4 other study(ies) available for l 645151 and acetazolamide
| Article | Year |
|---|---|
Topically active carbonic anhydrase inhibitors. 2. Benzo[b]thiophenesulfonamide derivatives with ocular hypotensive activity.
Topics: Animals; Carbonic Anhydrase Inhibitors; Chemical Phenomena; Chemistry; Glaucoma; Guinea Pigs; Intraocular Pressure; Ocular Hypertension; Rabbits; Skin; Sulfonamides; Thiophenes | 1989 |
Topically active carbonic anhydrase inhibitors. 1. O-acyl derivatives of 6-hydroxybenzothiazole-2-sulfonamide.
Topics: Animals; Benzothiazoles; Carbonic Anhydrase Inhibitors; Chemical Phenomena; Chemistry; Cornea; Ethoxzolamide; Guinea Pigs; Humans; Intraocular Pressure; Ophthalmic Solutions; Prodrugs; Rabbits; Thiazoles | 1989 |
Inhibition of muscle carbonic anhydrase increases rise and relaxation times of twitches in rat skeletal muscle fibres.
Topics: Acetazolamide; Animals; Benzolamide; Benzothiazoles; Bicarbonates; Buffers; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Ethoxzolamide; Female; HEPES; Hydrogen-Ion Concentration; Muscle Contraction; Muscle Fibers, Skeletal; Muscle Relaxation; Muscle, Skeletal; Rats; Rats, Inbred WF; Sarcoplasmic Reticulum; Thiadiazoles; Thiazoles | 2002 |
Inhibition of muscle carbonic anhydrase slows the Ca(2+) transient in rat skeletal muscle fibers.
Topics: Acetazolamide; Action Potentials; Adenosine Triphosphatases; Animals; Benzothiazoles; Calcium; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Chelating Agents; Dose-Response Relationship, Drug; Enzyme Activation; Ethoxzolamide; Female; Fura-2; In Vitro Techniques; Ion Transport; Isometric Contraction; Muscle Contraction; Muscle Fibers, Skeletal; Muscle, Skeletal; Rats; Sarcoplasmic Reticulum; Thiadiazoles; Thiazoles; Time Factors | 2002 |