l 368899 and opc 21268
l 368899 has been researched along with opc 21268 in 3 studies
*OPC 21268: structure given in first source; vasopressin V1 receptor antagonist [MeSH]
*OPC 21268: structure given in first source; vasopressin V1 receptor antagonist [MeSH]
Compound Research Comparison
| Studies (l 368899) | Trials (l 368899) | Recent Studies (post-2010) (l 368899) | Studies (opc 21268) | Trials (opc 21268) | Recent Studies (post-2010) (opc 21268) |
|---|---|---|---|---|---|
| 6 | 0 | 4 | 133 | 3 | 6 |
| 46 | 0 | 30 | 133 | 3 | 6 |
Protein Interaction Comparison
| Protein | Taxonomy | l 368899 (IC50) | opc 21268 (IC50) |
|---|---|---|---|
| Vasopressin V1a receptor | Rattus norvegicus (Norway rat) | 0.44 |
Research
Studies (3)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Harrell, CM; Jasper, JR; O'Brien, JA; Pettibone, DJ | 1 |
| Borthwick, AD | 1 |
| Honda, K; Ikeda, K; Onaka, T; Yamashita, T | 1 |
Other Studies
3 other study(ies) available for l 368899 and opc 21268
| Article | Year |
|---|---|
Characterization of the human oxytocin receptor stably expressed in 293 human embryonic kidney cells.
Topics: Arginine Vasopressin; Cell Line; Drug Tolerance; Embryo, Mammalian; Female; Gene Expression; Guanine Nucleotides; Humans; Hydrolysis; Kidney; Myometrium; Oxytocin; Phosphatidylinositols; Receptors, Oxytocin; Recombinant Proteins; Transfection; Tritium | 1995 |
Oral oxytocin antagonists.
Topics: Administration, Oral; Animals; Biological Availability; Camphor; Humans; Indoles; Oxytocin; Piperazines; Piperidines; Protein Conformation; Pyrrolidines; Receptors, Oxytocin; Sulfonamides; Triazoles | 2010 |
Facilitative role of endogenous oxytocin in noradrenaline release in the rat supraoptic nucleus.
Topics: Analysis of Variance; Animals; Antidiuretic Hormone Receptor Antagonists; Brain Chemistry; Camphanes; Conditioning, Psychological; Dose-Response Relationship, Drug; Drug Interactions; Electrochemistry; Electroshock; Fear; Male; Microdialysis; Norepinephrine; Oxytocin; Piperazines; Piperidines; Potassium; Quinolones; Radioimmunoassay; Rats; Rats, Wistar; Receptors, Oxytocin; Stimulation, Chemical; Supraoptic Nucleus; Synaptosomes | 2003 |