Page last updated: 2024-09-05

l 163191 and sk&f 110679

l 163191 has been researched along with sk&f 110679 in 4 studies

Compound Research Comparison

Studies
(l 163191)
Trials
(l 163191)
Recent Studies (post-2010)
(l 163191)
Studies
(sk&f 110679)
Trials
(sk&f 110679)
Recent Studies (post-2010) (sk&f 110679)
35017701

Protein Interaction Comparison

ProteinTaxonomyl 163191 (IC50)sk&f 110679 (IC50)
Platelet glycoprotein 4Rattus norvegicus (Norway rat)1.82
Growth hormone secretagogue receptor type 1Homo sapiens (human)2.0032

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (75.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chaung, LY; Dean, DC; Ellsworth, RL; Griffin, P; Melillo, DG; Nargund, RP; Patchett, AA; Pong, SS; Smith, RG; Van der Ploeg, LH1
Bach, MA; Murphy, MG; Nargund, RP; Patchett, AA; Smith, RG1
Chan, WW; Cheng, K; Jacks, T; Morriello, G; Patchett, AA; Prendergast, K; Schleim, KD; Smith, RG; Yang, L1
Bakshi, RK; Birzin, ET; Blake, A; Chan, WW; Chen, MH; Feighner, SD; Gao, Y; Howard, AD; Locco, L; Nargund, RP; Parmar, RM; Patchett, AA; Pong, SS; Rohrer, SP; Schaeffer, JM; Smith, RG; Ye, Z1

Reviews

1 review(s) available for l 163191 and sk&f 110679

ArticleYear
Peptidomimetic growth hormone secretagogues. Design considerations and therapeutic potential.
    Journal of medicinal chemistry, 1998, Aug-13, Volume: 41, Issue:17

    Topics: Amino Acid Sequence; Animals; Drug Design; Growth Hormone-Releasing Hormone; Hormones; Human Growth Hormone; Humans; Hypothalamo-Hypophyseal System; Molecular Sequence Data; Oligopeptides; Protein Conformation; Receptors, Somatotropin

1998

Other Studies

3 other study(ies) available for l 163191 and sk&f 110679

ArticleYear
Development of a high specific activity sulfur-35-labeled sulfonamide radioligand that allowed the identification of a new growth hormone secretagogue receptor.
    Journal of medicinal chemistry, 1996, Apr-26, Volume: 39, Issue:9

    Topics: Amino Acid Sequence; Animals; Indoles; Molecular Sequence Data; Radioligand Assay; Rats; Receptors, Somatotropin; Spiro Compounds; Sulfonamides; Sulfur Radioisotopes

1996
Potent 3-spiropiperidine growth hormone secretagogues.
    Bioorganic & medicinal chemistry letters, 1998, Jan-06, Volume: 8, Issue:1

    Topics: Animals; Growth Hormone; In Vitro Techniques; Indoles; Piperidines; Pituitary Gland; Rats; Spiro Compounds; Structure-Activity Relationship

1998
Modeling directed design and biological evaluation of quinazolinones as non-peptidic growth hormone secretagogues.
    Bioorganic & medicinal chemistry letters, 2000, Jan-03, Volume: 10, Issue:1

    Topics: Animals; Binding Sites; Drug Design; Human Growth Hormone; Humans; Inhibitory Concentration 50; Kinetics; Models, Molecular; Quinazolines; Rats; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Ghrelin; Secretory Rate; Structure-Activity Relationship

2000