Compounds > l 163191
Page last updated: 2024-09-05

l 163191 and pha 848125

l 163191 has been researched along with pha 848125 in 3 studies

Compound Research Comparison

Studies
(l 163191)		Trials
(l 163191)		Recent Studies (post-2010)
(l 163191)		Studies
(pha 848125)		Trials
(pha 848125)		Recent Studies (post-2010) (pha 848125)
3501730125

Protein Interaction Comparison

ProteinTaxonomyl 163191 (IC50)pha 848125 (IC50)
Aurora kinase AHomo sapiens (human)0.5288
Cyclin-T1Homo sapiens (human)7.7
Tyrosine-protein kinase ABL1Homo sapiens (human)0.478
Epidermal growth factor receptorHomo sapiens (human)3.069
High affinity nerve growth factor receptorHomo sapiens (human)0.053
Tyrosine-protein kinase LckHomo sapiens (human)0.209
Cyclin-dependent kinase 1Homo sapiens (human)0.4661
Proto-oncogene tyrosine-protein kinase receptor RetHomo sapiens (human)1.933
Mast/stem cell growth factor receptor KitHomo sapiens (human)0.668
Fibroblast growth factor receptor 1Homo sapiens (human)1.207
Cyclin-dependent kinase 4Homo sapiens (human)0.18
G2/mitotic-specific cyclin-B1Homo sapiens (human)0.4661
Cyclin-A2Homo sapiens (human)0.2855
G1/S-specific cyclin-D1Homo sapiens (human)0.18
G1/S-specific cyclin-E1Homo sapiens (human)0.3881
Cyclin-dependent kinase 2Homo sapiens (human)0.2563
Vascular endothelial growth factor receptor 3Homo sapiens (human)0.92
Cyclin-dependent kinase 7Homo sapiens (human)0.19
Cyclin-dependent kinase 9Homo sapiens (human)7.7
Cyclin-HHomo sapiens (human)0.19
CDK-activating kinase assembly factor MAT1Homo sapiens (human)0.27
Cyclin-dependent-like kinase 5 Homo sapiens (human)0.3467
Cyclin-dependent kinase 5 activator 1Homo sapiens (human)0.3467
Aurora kinase BHomo sapiens (human)4.175
Serine/threonine-protein kinase Nek6Homo sapiens (human)1.065

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Jadhav, A; Kerns, E; Nguyen, K; Shah, P; Sun, H; Xu, X; Yan, Z; Yu, KR1
Kabir, M; Kerns, E; Nguyen, K; Shah, P; Sun, H; Wang, Y; Xu, X; Yu, KR1
Kabir, M; Kerns, E; Neyra, J; Nguyen, K; Nguyễn, ÐT; Shah, P; Siramshetty, VB; Southall, N; Williams, J; Xu, X; Yu, KR1

Other Studies

3 other study(ies) available for l 163191 and pha 848125

ArticleYear
Highly predictive and interpretable models for PAMPA permeability.
    Bioorganic & medicinal chemistry, 2017, 02-01, Volume: 25, Issue:3

    Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Humans; Models, Biological; Organic Chemicals; Regression Analysis; Support Vector Machine

2017
Predictive models of aqueous solubility of organic compounds built on A large dataset of high integrity.
    Bioorganic & medicinal chemistry, 2019, 07-15, Volume: 27, Issue:14

    Topics: Drug Discovery; Organic Chemicals; Pharmaceutical Preparations; Solubility

2019
Retrospective assessment of rat liver microsomal stability at NCATS: data and QSAR models.
    Scientific reports, 2020, 11-26, Volume: 10, Issue:1

    Topics: Animals; Computer Simulation; Databases, Factual; Drug Discovery; High-Throughput Screening Assays; Liver; Machine Learning; Male; Microsomes, Liver; National Center for Advancing Translational Sciences (U.S.); Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Rats; Rats, Sprague-Dawley; Retrospective Studies; United States

2020