l 163191 has been researched along with l 692429 in 8 studies
| Studies (l 163191) | Trials (l 163191) | Recent Studies (post-2010) (l 163191) | Studies (l 692429) | Trials (l 692429) | Recent Studies (post-2010) (l 692429) |
|---|---|---|---|---|---|
| 35 | 0 | 17 | 40 | 5 | 1 |
| Protein | Taxonomy | l 163191 (IC50) | l 692429 (IC50) |
|---|---|---|---|
| Growth hormone secretagogue receptor type 1 | Rattus norvegicus (Norway rat) | 0.06 | |
| Type-1 angiotensin II receptor | Homo sapiens (human) | 3.6 | |
| Growth hormone secretagogue receptor type 1 | Homo sapiens (human) | 2.8 | |
| Growth hormone secretagogue receptor type 1 | Sus scrofa (pig) | 0.063 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 4 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Chaung, LY; Dean, DC; Ellsworth, RL; Griffin, P; Melillo, DG; Nargund, RP; Patchett, AA; Pong, SS; Smith, RG; Van der Ploeg, LH | 1 |
| Bach, MA; Murphy, MG; Nargund, RP; Patchett, AA; Smith, RG | 1 |
| Chan, WW; Cheng, K; Jacks, T; Morriello, G; Patchett, AA; Prendergast, K; Schleim, KD; Smith, RG; Yang, L | 1 |
| Hourai, S; Hume, WE; Kumagai, K; Nagamine, J; Nagata, R; Noguchi, H; Okazaki, K; Seki, H; Taiji, M; Tokunaga, T; Ueki, Y; Umezome, T | 1 |
| Butler, B; Chan, WW; Cheng, K; Hickey, G; Jacks, TM; Lu, Z; Patchett, AA; Schleim, KD; Tata, JR; Wei, L | 1 |
| Ankersen, M; Bondensgaard, K; Bywater, RP; Hansen, BS; Thøgersen, H; Wulff, BS | 1 |
| Bach, A; Brandt, E; Heding, A; Holst, B; Schwartz, TW | 1 |
| Bukhari, SNA | 1 |
2 review(s) available for l 163191 and l 692429
| Article | Year |
|---|---|
Peptidomimetic growth hormone secretagogues. Design considerations and therapeutic potential.
Topics: Amino Acid Sequence; Animals; Drug Design; Growth Hormone-Releasing Hormone; Hormones; Human Growth Hormone; Humans; Hypothalamo-Hypophyseal System; Molecular Sequence Data; Oligopeptides; Protein Conformation; Receptors, Somatotropin | 1998 |
An insight into the multifunctional role of ghrelin and structure activity relationship studies of ghrelin receptor ligands with clinical trials.
Topics: Animals; Clinical Trials as Topic; Ghrelin; Growth Hormone; Ligands; Peptidomimetics; Receptors, Ghrelin; Structure-Activity Relationship | 2022 |
6 other study(ies) available for l 163191 and l 692429
| Article | Year |
|---|---|
Development of a high specific activity sulfur-35-labeled sulfonamide radioligand that allowed the identification of a new growth hormone secretagogue receptor.
Topics: Amino Acid Sequence; Animals; Indoles; Molecular Sequence Data; Radioligand Assay; Rats; Receptors, Somatotropin; Spiro Compounds; Sulfonamides; Sulfur Radioisotopes | 1996 |
Potent 3-spiropiperidine growth hormone secretagogues.
Topics: Animals; Growth Hormone; In Vitro Techniques; Indoles; Piperidines; Pituitary Gland; Rats; Spiro Compounds; Structure-Activity Relationship | 1998 |
Oxindole derivatives as orally active potent growth hormone secretagogues.
Topics: Administration, Oral; Animals; Biological Availability; Body Weight; CHO Cells; Cricetinae; Crystallography, X-Ray; Ethylamines; Female; Growth Hormone; Human Growth Hormone; Humans; In Vitro Techniques; Indoles; Male; Models, Molecular; Molecular Conformation; Pituitary Gland, Anterior; Rats; Rats, Inbred F344; Rats, Wistar; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Ghrelin; Stereoisomerism; Structure-Activity Relationship | 2001 |
Substituted bridged phenyl piperidines: orally active growth hormone secretagogues.
Topics: Administration, Oral; Animals; Biological Availability; Dogs; Growth Hormone; Piperidines; Pituitary Gland; Rats; Structure-Activity Relationship | 2003 |
Recognition of privileged structures by G-protein coupled receptors.
Topics: Amino Acid Sequence; Animals; Binding Sites; Biphenyl Compounds; Cell Line; Conserved Sequence; Cricetinae; Indans; Indoles; Ligands; Models, Molecular; Molecular Sequence Data; Piperidines; Receptor, Angiotensin, Type 1; Receptor, Melanocortin, Type 4; Receptors, G-Protein-Coupled; Receptors, Ghrelin; Receptors, Serotonin; Sequence Alignment; Spiro Compounds; Tetrazoles | 2004 |
Nonpeptide and peptide growth hormone secretagogues act both as ghrelin receptor agonist and as positive or negative allosteric modulators of ghrelin signaling.
Topics: Allosteric Regulation; Amino Acid Sequence; Animals; Arrestin; Benzazepines; Calcium; CREB-Binding Protein; Ghrelin; Humans; Indoles; Inositol Phosphates; Molecular Sequence Data; Molecular Structure; Oligopeptides; Peptide Hormones; Receptors, G-Protein-Coupled; Receptors, Ghrelin; Response Elements; Serum Response Element; Signal Transduction; Spiro Compounds; Tetrazoles; Transcription, Genetic | 2005 |