Compounds > l 163191
Page last updated: 2024-09-05

l 163191 and astemizole

l 163191 has been researched along with astemizole in 3 studies

Compound Research Comparison

Studies
(l 163191)		Trials
(l 163191)		Recent Studies (post-2010)
(l 163191)		Studies
(astemizole)		Trials
(astemizole)		Recent Studies (post-2010) (astemizole)
350171,130117578

Protein Interaction Comparison

ProteinTaxonomyl 163191 (IC50)astemizole (IC50)
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)1.1
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.179
Bile salt export pumpHomo sapiens (human)10
Epidermal growth factor receptorHomo sapiens (human)6.057
Tyrosine-protein kinase FynHomo sapiens (human)2.847
ATP-dependent translocase ABCB1Mus musculus (house mouse)1.7
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)1.375
Muscarinic acetylcholine receptor M2Homo sapiens (human)1.409
Muscarinic acetylcholine receptor M4Homo sapiens (human)1.861
ATP-dependent translocase ABCB1Homo sapiens (human)0.9667
Cytochrome P450 3A4Homo sapiens (human)3.3
Muscarinic acetylcholine receptor M5Homo sapiens (human)0.703
Alpha-2A adrenergic receptorHomo sapiens (human)4.846
Muscarinic acetylcholine receptor M1Homo sapiens (human)1.066
Beta-3 adrenergic receptorHomo sapiens (human)8.06
D(2) dopamine receptorHomo sapiens (human)4.521
Alpha-2B adrenergic receptorHomo sapiens (human)3.839
Alpha-2C adrenergic receptorHomo sapiens (human)1.959
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.767
Muscarinic acetylcholine receptor M3Homo sapiens (human)0.84
ATP-dependent translocase ABCB1Mus musculus (house mouse)1.3
Substance-K receptorHomo sapiens (human)2.986
D(1A) dopamine receptorHomo sapiens (human)4.01
D(4) dopamine receptorHomo sapiens (human)6.087
Sodium-dependent noradrenaline transporter Homo sapiens (human)1.375
Histamine H2 receptorHomo sapiens (human)1.682
Alpha-1D adrenergic receptorHomo sapiens (human)0.769
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.02
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.179
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)0.767
Sodium-dependent serotonin transporterHomo sapiens (human)1.318
Melanocortin receptor 5Homo sapiens (human)2.263
Histamine H1 receptorHomo sapiens (human)0.014
Mu-type opioid receptorHomo sapiens (human)1.492
D(3) dopamine receptorHomo sapiens (human)0.436
Kappa-type opioid receptorHomo sapiens (human)6.616
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.012
5-hydroxytryptamine receptor 6Homo sapiens (human)3.266
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)1.1
Sodium-dependent dopamine transporter Homo sapiens (human)0.998
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.2857
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)1.1
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)1.1
Sigma non-opioid intracellular receptor 1Homo sapiens (human)2.246

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Jadhav, A; Kerns, E; Nguyen, K; Shah, P; Sun, H; Xu, X; Yan, Z; Yu, KR1
Kabir, M; Kerns, E; Nguyen, K; Shah, P; Sun, H; Wang, Y; Xu, X; Yu, KR1
Kabir, M; Kerns, E; Neyra, J; Nguyen, K; Nguyễn, ÐT; Shah, P; Siramshetty, VB; Southall, N; Williams, J; Xu, X; Yu, KR1

Other Studies

3 other study(ies) available for l 163191 and astemizole

ArticleYear
Highly predictive and interpretable models for PAMPA permeability.
    Bioorganic & medicinal chemistry, 2017, 02-01, Volume: 25, Issue:3

    Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Humans; Models, Biological; Organic Chemicals; Regression Analysis; Support Vector Machine

2017
Predictive models of aqueous solubility of organic compounds built on A large dataset of high integrity.
    Bioorganic & medicinal chemistry, 2019, 07-15, Volume: 27, Issue:14

    Topics: Drug Discovery; Organic Chemicals; Pharmaceutical Preparations; Solubility

2019
Retrospective assessment of rat liver microsomal stability at NCATS: data and QSAR models.
    Scientific reports, 2020, 11-26, Volume: 10, Issue:1

    Topics: Animals; Computer Simulation; Databases, Factual; Drug Discovery; High-Throughput Screening Assays; Liver; Machine Learning; Male; Microsomes, Liver; National Center for Advancing Translational Sciences (U.S.); Pharmaceutical Preparations; Quantitative Structure-Activity Relationship; Rats; Rats, Sprague-Dawley; Retrospective Studies; United States

2020