Page last updated: 2024-09-03

l 158809 and candesartan

l 158809 has been researched along with candesartan in 3 studies

Compound Research Comparison

Studies
(l 158809)
Trials
(l 158809)
Recent Studies (post-2010)
(l 158809)
Studies
(candesartan)
Trials
(candesartan)
Recent Studies (post-2010) (candesartan)
137071,929412589

Protein Interaction Comparison

ProteinTaxonomyl 158809 (IC50)candesartan (IC50)
Epidermal growth factor receptorHomo sapiens (human)3.2769
Receptor tyrosine-protein kinase erbB-2Homo sapiens (human)5.9472
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)3.0652
Cytochrome P450 3A4Homo sapiens (human)9
Adenosine receptor A3Homo sapiens (human)1.2199
Cytochrome P450 2C9 Homo sapiens (human)3
Beta-3 adrenergic receptorHomo sapiens (human)4.3
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)1.2199
Alpha-2B adrenergic receptorHomo sapiens (human)3.843
Sodium-dependent noradrenaline transporter Homo sapiens (human)3.0652
Thromboxane-A synthase Homo sapiens (human)3.0594
Type-1 angiotensin II receptorHomo sapiens (human)0.0405
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)1.2199

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Goldberg, MR; Greenlee, WJ; Irvin, JD; Prendergast, K; Smith, RD; Timmermans, PB; Wexler, RR1
Berellini, G; Cruciani, G; Mannhold, R1
Giridhar, R; Murumkar, P; Naik, P; Yadav, MR1

Reviews

2 review(s) available for l 158809 and candesartan

ArticleYear
Nonpeptide angiotensin II receptor antagonists: the next generation in antihypertensive therapy.
    Journal of medicinal chemistry, 1996, Feb-02, Volume: 39, Issue:3

    Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Humans; Receptors, Angiotensin; Structure-Activity Relationship

1996
Angiotensin II receptor type 1 (AT1) selective nonpeptidic antagonists--a perspective.
    Bioorganic & medicinal chemistry, 2010, Dec-15, Volume: 18, Issue:24

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Antihypertensive Agents; Humans; Losartan

2010

Other Studies

1 other study(ies) available for l 158809 and candesartan

ArticleYear
Pharmacophore, drug metabolism, and pharmacokinetics models on non-peptide AT1, AT2, and AT1/AT2 angiotensin II receptor antagonists.
    Journal of medicinal chemistry, 2005, Jun-30, Volume: 48, Issue:13

    Topics: Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Binding Sites; Biphenyl Compounds; Kinetics; Losartan; Models, Molecular; Molecular Conformation; Oxidation-Reduction; Pharmaceutical Preparations; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Structure-Activity Relationship; Tetrazoles

2005