Page last updated: 2024-09-03

kyotorphin and ubenimex

kyotorphin has been researched along with ubenimex in 8 studies

Compound Research Comparison

Studies
(kyotorphin)
Trials
(kyotorphin)
Recent Studies (post-2010)
(kyotorphin)
Studies
(ubenimex)
Trials
(ubenimex)
Recent Studies (post-2010) (ubenimex)
16802293043182

Protein Interaction Comparison

ProteinTaxonomykyotorphin (IC50)ubenimex (IC50)
Aminopeptidase BRattus norvegicus (Norway rat)6
M1 family aminopeptidasePlasmodium falciparum FcB1/Columbia0.284
Cytosol aminopeptidaseBos taurus (cattle)1.0005
72 kDa type IV collagenaseHomo sapiens (human)6.45
Leukotriene A-4 hydrolaseHomo sapiens (human)1.4742
Aminopeptidase NHomo sapiens (human)2.6333
Aminopeptidase NSus scrofa (pig)3.8211
Angiotensin-converting enzymeRattus norvegicus (Norway rat)2.7
Puromycin-sensitive aminopeptidaseHomo sapiens (human)3.5
Bacterial leucyl aminopeptidaseVibrio proteolyticus1.0005

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19905 (62.50)18.7374
1990's3 (37.50)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Orawski, AT; Simmons, WH1
Akasaki, K; Nakamura, A; Shiomi, H; Tsuji, H1
Imajoh, S; Satoh, M; Takagi, H; Ueda, H; Yoshihara, Y1
Hazato, T; Katayama, T; Ming, G; Takagi, H; Ueda, H1
Iwama, T; Satoh, M; Takagi, H; Wada, T1
Nakamura, A; Satoh, M; Shiomi, H; Takagi, H; Ueda, H; Yoshihara, Y1
Kawajiri, S; Kojima, C; Matsubayashi, K; Ono, K; Takagi, H; Takegoshi, T; Ueda, H1
Awazu, S; Koyanagi, A; Mizuma, T1

Other Studies

8 other study(ies) available for kyotorphin and ubenimex

ArticleYear
Dipeptidase activities in rat brain synaptosomes can be distinguished on the basis of inhibition by bestatin and amastatin: identification of a kyotorphin (Tyr-Arg)-degrading enzyme.
    Neurochemical research, 1992, Volume: 17, Issue:8

    Topics: Animals; Anti-Bacterial Agents; Brain; Chromatography, Gel; Detergents; Dipeptidases; Endorphins; Leucine; Oligopeptides; Peptides; Rats; Rats, Inbred Strains; Substrate Specificity; Synaptosomes

1992
Identification and characterization of two distinct kyotorphin-hydrolyzing enzymes in rat brain.
    Neuropeptides, 1991, Volume: 20, Issue:2

    Topics: Aminopeptidases; Animals; Brain; Chromatography, Gel; Cytosol; Dipeptidases; Endorphins; Immunoblotting; Immunosorbent Techniques; Leucine; Male; Molecular Weight; Peptide Hydrolases; Protease Inhibitors; Rats; Rats, Inbred Strains

1991
Calcium-activated neutral protease (CANP), a putative processing enzyme of the neuropeptide, kyotorphin, in the brain.
    Biochemical and biophysical research communications, 1988, Sep-15, Volume: 155, Issue:2

    Topics: Animals; Brain; Calcium; Calpain; Endorphins; Hydrogen-Ion Concentration; Leucine; Male; Rats; Rats, Inbred Strains; Sulfhydryl Reagents; Synaptosomes; Time Factors

1988
Degradation of kyotorphin by a purified membrane-bound-aminopeptidase from monkey brain: potentiation of kyotorphin-induced analgesia by a highly effective inhibitor, bestatin.
    Life sciences, 1985, May-13, Volume: 36, Issue:19

    Topics: Aminopeptidases; Analgesics; Animals; Brain; Drug Synergism; Endorphins; In Vitro Techniques; Kinetics; Leucine; Macaca fascicularis; Male; Membranes; Mice; Mice, Inbred Strains; Protein Binding; Rats; Rats, Inbred Strains

1985
Sites of analgesic actions of kyotorphin and D-kyotorphin in the central nervous system of rats.
    Neuropeptides, 1985, Volume: 5, Issue:4-6

    Topics: Analgesics; Animals; Central Nervous System; Endorphins; Enkephalins; Leucine; Male; Naloxone; Periaqueductal Gray; Rats; Rats, Inbred Strains; Reticular Formation; Spinal Cord

1985
How is kyotorphin (Tyr-Arg) generated in the brain?
    Neuropeptides, 1985, Volume: 5, Issue:4-6

    Topics: Animals; Brain; Endorphins; Hypothalamus; Leucine; Rats; Rats, Inbred Strains; Subcellular Fractions; Synaptosomes

1985
Hydrolytic deactivation of kyotorphin by the rodent brain homogenates and sera.
    Journal of pharmacobio-dynamics, 1984, Volume: 7, Issue:7

    Topics: Analgesics; Animals; Brain; Drug Stability; Endorphins; Kinetics; Leucine; Male; Mice; Mice, Inbred Strains; Rats; Rats, Inbred Strains

1984
Intestinal transport and metabolism of analgesic dipeptide, kyotorphin: rate-limiting factor in intestinal absorption of peptide as drug.
    Biochimica et biophysica acta, 1997, Apr-17, Volume: 1335, Issue:1-2

    Topics: Analgesics; Animals; Biological Transport; Endorphins; Intestinal Absorption; Intestinal Mucosa; Intestine, Small; Leucine; Metabolic Clearance Rate; Phenanthrolines; Protease Inhibitors; Rats; Tryptophan

1997