kyotorphin has been researched along with naloxone in 18 studies
| Studies (kyotorphin) | Trials (kyotorphin) | Recent Studies (post-2010) (kyotorphin) | Studies (naloxone) | Trials (naloxone) | Recent Studies (post-2010) (naloxone) |
|---|---|---|---|---|---|
| 168 | 0 | 22 | 20,134 | 1,257 | 3,321 |
| Protein | Taxonomy | kyotorphin (IC50) | naloxone (IC50) |
|---|---|---|---|
| Cytochrome P450 2D6 | Homo sapiens (human) | 2 | |
| Delta-type opioid receptor | Mus musculus (house mouse) | 0.043 | |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0219 | |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0019 | |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | 0.0019 | |
| Mu-type opioid receptor | Homo sapiens (human) | 0.0397 | |
| Delta-type opioid receptor | Homo sapiens (human) | 0.1896 | |
| Kappa-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.05 | |
| Kappa-type opioid receptor | Homo sapiens (human) | 0.0795 | |
| Mu-type opioid receptor | Mus musculus (house mouse) | 0.0154 | |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 0.0089 | |
| Beta-2 adrenergic receptor | Cavia porcellus (domestic guinea pig) | 0.0055 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (77.78) | 18.7374 |
| 1990's | 2 (11.11) | 18.2507 |
| 2000's | 1 (5.56) | 29.6817 |
| 2010's | 1 (5.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hirai, K; Katayama, Y | 1 |
| Chepkova, AN; Zotov, VM | 1 |
| Iwama, T; Satoh, M; Takagi, H; Wada, T | 1 |
| Bean, AJ; Vaught, JL | 2 |
| Ijichi, H; Kizu, A; Nakagawa, M; Shimamura, O; Yamasaki, Y | 1 |
| Balderrama, N; Maldonado, H; Miralto, A; Núñez, J | 1 |
| Akutsu, Y; Kawamura, S; Kisara, K; Sakurada, S; Sakurada, T; Sasaki, Y; Suzuki, K | 1 |
| Akutsu, Y; Kawamura, S; Kisara, K; Sakurada, S; Sakurada, T; Sasaki, Y; Sato, T; Suzuki, K; Watanabe, S | 1 |
| Stone, TW | 1 |
| Chipkin, RE; Vaught, JL | 1 |
| Akaike, A; Kawajiri, S; Satoh, M; Takagi, H; Ukai, Y; Yamamoto, M | 1 |
| Kawamuki, K; Satoh, M; Takagi, H; Yamamoto, M | 1 |
| Baile, CA; Della-Fera, MA; Keim, DA; McLaughlin, CL | 1 |
| Peng, SQ; Qiu, XC; Wang, C; Zhu, Y | 1 |
| Kawabata, A; Takagi, H; Umeda, N | 1 |
| Browning, KN; Kalyuzhny, AE; Travagli, RA | 1 |
| Bocheva, AI; Bozhilova-Pastirova, AA; Dzambazova, EB; Landzhov, BV | 1 |
18 other study(ies) available for kyotorphin and naloxone
| Article | Year |
|---|---|
Effect of the endogenous analgesic dipeptide, kyotorphin, on transmitter release in sympathetic ganglia.
Topics: Acetylcholine; Action Potentials; Analgesics; Animals; Endorphins; Female; Ganglia, Sympathetic; In Vitro Techniques; Male; Membrane Potentials; Naloxone; Neurotransmitter Agents; Rana catesbeiana | 1985 |
[Effect of kyotorphin on the reactivity of hippocampal neurons].
Topics: Action Potentials; Animals; Electric Stimulation; Endorphins; Enkephalin, Methionine; Hippocampus; In Vitro Techniques; Naloxone; Neurons; Rats; Rats, Inbred Strains | 1986 |
Sites of analgesic actions of kyotorphin and D-kyotorphin in the central nervous system of rats.
Topics: Analgesics; Animals; Central Nervous System; Endorphins; Enkephalins; Leucine; Male; Naloxone; Periaqueductal Gray; Rats; Rats, Inbred Strains; Reticular Formation; Spinal Cord | 1985 |
Physical dependence produced by chronic intracerebroventricular infusion of [D-Arg]kyotorphin or thiorphan to rats.
Topics: Amino Acids, Sulfur; Analgesics; Animals; Cerebral Ventricles; Endorphins; Humans; Male; Morphine; Naloxone; Neprilysin; Opioid-Related Disorders; Protease Inhibitors; Rats; Rats, Inbred Strains; Receptors, Opioid; Substance Withdrawal Syndrome; Thiorphan; Tiopronin | 1984 |
Lack of active site for kyotorphin in rat mast cells: assessment by its effect on IgE-mediated 14C-serotonin release.
Topics: Alprostadil; Animals; Endorphins; Immunoglobulin E; In Vitro Techniques; Mast Cells; Naloxone; Narcotics; Prostaglandins E; Rats; Rats, Inbred Strains; Receptors, Opioid; Serotonin | 1982 |
[D-Arg]Kyotorphin-induced ipsilateral rotation: evidence for in vivo effects independent of Met-enkephalin release.
Topics: Animals; Endorphins; Enkephalin, Methionine; Male; Motor Activity; Naloxone; Rats; Rats, Inbred Strains; Rotation; Substantia Nigra | 1984 |
The stinging response of the honeybee: effects of morphine, naloxone and some opioid peptides.
Topics: Animals; Bees; Behavior, Animal; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Insect Bites and Stings; Morphine; Naloxone | 1983 |
Antinociceptive effect of centrally administered cyclo(N-methyl-L-Tyr-L-Arg) in the rat.
Topics: Analgesics; Animals; Endorphins; Injections, Intraventricular; Injections, Spinal; Male; Morphine; Naloxone; Peptides, Cyclic; Rats; Rats, Inbred Strains; Reaction Time; Time Factors | 1983 |
Comparison of the antinociceptive effects of intracerebroventricular injection of kyotorphin, cyclo (N-methyl-Tyr-Arg) and Met-enkephalin in mice.
Topics: Analgesia; Analgesics; Animals; Endorphins; Enkephalin, Methionine; Injections, Intraventricular; Male; Mice; Naloxone; Nociceptors; Peptides, Cyclic | 1984 |
A comparison of the effects of morphine, enkephalin, kyotorphin and D-phenylalanine on rat central neurones.
Topics: Animals; Brain; Cerebral Cortex; Endorphins; Enkephalin, Methionine; Globus Pallidus; Iontophoresis; Male; Morphine; Naloxone; Neurons; Phenylalanine; Rats | 1983 |
A characterization of kyotorphin (Tyr-Arg)-induced antinociception.
Topics: Analgesics; Animals; Dipeptides; Dose-Response Relationship, Drug; Endopeptidases; Endorphins; Injections, Intraventricular; Injections, Spinal; Male; Mice; Naloxone; Neprilysin; Rats; Rats, Inbred Strains; Time Factors | 1982 |
Effects of tyrosyl-arginine (kyotorphin), a new opioid dipeptide, on single neurons in the spinal dorsal horn of rabbits and the nucleus reticularis paragigantocellularis of rats.
Topics: Animals; Endorphins; Guinea Pigs; Iontophoresis; Male; Medulla Oblongata; Microinjections; Naloxone; Rabbits; Rats; Rats, Inbred Strains; Spinal Cord | 1980 |
Kyotorphin (L-Tyr-L-Arg) inhibits extinction of pole-jumping avoidance response in the rat.
Topics: Animals; Avoidance Learning; Endorphins; Enkephalin, Leucine; Extinction, Psychological; Injections, Intraventricular; Injections, Subcutaneous; Male; Naloxone; Rats; Rats, Inbred Strains | 1982 |
Opiate antagonists and agonists and feeding in sheep.
Topics: Animals; Dipeptides; Drinking; Drug Interactions; Endorphins; Enkephalins; Feeding Behavior; Male; Naloxone; Narcotic Antagonists; Sheep; Water Deprivation | 1981 |
[The permissive action of glucocorticoid on the analgesic effect of kyotorphin and its analogue].
Topics: Analgesics; Animals; Dose-Response Relationship, Drug; Drug Synergism; Endorphins; Female; Hydrocortisone; Male; Naloxone; Pain Threshold; Rats; Rats, Wistar; Stereoisomerism | 1993 |
L-arginine exerts a dual role in nociceptive processing in the brain: involvement of the kyotorphin-Met-enkephalin pathway and NO-cyclic GMP pathway.
Topics: Analgesics; Animals; Arginine; Brain; Cyclic GMP; Endorphins; Enkephalin, Methionine; Injections, Intraventricular; Male; Methylene Blue; Mice; Mice, Inbred Strains; Naloxone; Naltrexone; Narcotic Antagonists; Neural Pathways; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nociceptors; Pain Measurement; Spinal Cord | 1993 |
Opioid peptides inhibit excitatory but not inhibitory synaptic transmission in the rat dorsal motor nucleus of the vagus.
Topics: Animals; Brain Stem; Digestive System; Electric Stimulation; Endorphins; Excitatory Postsynaptic Potentials; Immunohistochemistry; In Vitro Techniques; Motor Neurons; Naloxone; Narcotic Antagonists; Neural Inhibition; Opioid Peptides; Patch-Clamp Techniques; Presynaptic Terminals; Rats; Receptors, Opioid, mu; Solitary Nucleus; Synaptic Transmission; Vagus Nerve | 2002 |
Effects of D-kyotorphin on nociception and NADPH-d neurons in rat's periaqueductal gray after immobilization stress.
Topics: Analgesics; Animals; Endorphins; Male; NADH Dehydrogenase; Naloxone; Neurons; Nitric Oxide; Nociception; Periaqueductal Gray; Rats; Rats, Wistar; Stress, Physiological | 2011 |