Page last updated: 2024-09-03

kyotorphin and morphine

kyotorphin has been researched along with morphine in 8 studies

Compound Research Comparison

Studies
(kyotorphin)
Trials
(kyotorphin)
Recent Studies (post-2010)
(kyotorphin)
Studies
(morphine)
Trials
(morphine)
Recent Studies (post-2010) (morphine)
16802244,2705,2008,695

Protein Interaction Comparison

ProteinTaxonomykyotorphin (IC50)morphine (IC50)
Delta-type opioid receptorMus musculus (house mouse)0.2939
Delta-type opioid receptorRattus norvegicus (Norway rat)0.2278
Kappa-type opioid receptorMus musculus (house mouse)0.0828
Mu-type opioid receptorRattus norvegicus (Norway rat)0.0385
Kappa-type opioid receptorRattus norvegicus (Norway rat)0.0545
Mu-type opioid receptorHomo sapiens (human)0.122
Delta-type opioid receptorHomo sapiens (human)0.1199
Kappa-type opioid receptorCavia porcellus (domestic guinea pig)0.9308
Kappa-type opioid receptorHomo sapiens (human)0.655
Mu-type opioid receptorMus musculus (house mouse)0.3305
Mu-type opioid receptorCavia porcellus (domestic guinea pig)0.202
Beta-2 adrenergic receptorCavia porcellus (domestic guinea pig)0.25

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19906 (75.00)18.7374
1990's0 (0.00)18.2507
2000's1 (12.50)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bean, AJ; Vaught, JL1
Balderrama, N; Maldonado, H; Miralto, A; Núñez, J1
Akutsu, Y; Kawamura, S; Kisara, K; Sakurada, S; Sakurada, T; Sasaki, Y; Suzuki, K1
Stone, TW1
Satoh, M1
Shiomi, H; Takagi, H; Ueda, H1
Goto, T; Motoyama, Y; Ochi, T1
Bardaji, E; Castanho, MA; Heras, M; Oliveira, M; Ribeiro, MM; Santos, SM; Santos, SS; Sousa, DSC; Tavares, I1

Reviews

1 review(s) available for kyotorphin and morphine

ArticleYear
[Mechanisms of analgesic action of opioid peptides (author's transl)].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1982, Volume: 102, Issue:1

    Topics: Analgesics; Animals; Cats; Depression, Chemical; Dipeptides; Electric Stimulation; Endorphins; Ganglia, Spinal; Humans; Medulla Oblongata; Morphine; Neurons; Rabbits; Rats

1982

Other Studies

7 other study(ies) available for kyotorphin and morphine

ArticleYear
Physical dependence produced by chronic intracerebroventricular infusion of [D-Arg]kyotorphin or thiorphan to rats.
    European journal of pharmacology, 1984, Oct-15, Volume: 105, Issue:3-4

    Topics: Amino Acids, Sulfur; Analgesics; Animals; Cerebral Ventricles; Endorphins; Humans; Male; Morphine; Naloxone; Neprilysin; Opioid-Related Disorders; Protease Inhibitors; Rats; Rats, Inbred Strains; Receptors, Opioid; Substance Withdrawal Syndrome; Thiorphan; Tiopronin

1984
The stinging response of the honeybee: effects of morphine, naloxone and some opioid peptides.
    Pharmacology, biochemistry, and behavior, 1983, Volume: 19, Issue:16

    Topics: Animals; Bees; Behavior, Animal; Endorphins; Enkephalin, Leucine; Enkephalin, Methionine; Insect Bites and Stings; Morphine; Naloxone

1983
Antinociceptive effect of centrally administered cyclo(N-methyl-L-Tyr-L-Arg) in the rat.
    European journal of pharmacology, 1983, Sep-16, Volume: 93, Issue:1-2

    Topics: Analgesics; Animals; Endorphins; Injections, Intraventricular; Injections, Spinal; Male; Morphine; Naloxone; Peptides, Cyclic; Rats; Rats, Inbred Strains; Reaction Time; Time Factors

1983
A comparison of the effects of morphine, enkephalin, kyotorphin and D-phenylalanine on rat central neurones.
    British journal of pharmacology, 1983, Volume: 79, Issue:1

    Topics: Animals; Brain; Cerebral Cortex; Endorphins; Enkephalin, Methionine; Globus Pallidus; Iontophoresis; Male; Morphine; Naloxone; Neurons; Phenylalanine; Rats

1983
Isolation and identification of an analgesic opioid dipeptide kyotorphin (Tyr-Arg) from bovine brain.
    Neuropharmacology, 1981, Volume: 20, Issue:7

    Topics: Amino Acid Sequence; Animals; Brain Chemistry; Cattle; Cisterna Magna; Dipeptides; Endorphins; Enkephalin, Methionine; Enkephalins; Injections; Male; Mice; Morphine

1981
The spinal antinociceptive effect of FR140423 is mediated through kyotorphin receptors.
    Life sciences, 2000, Volume: 66, Issue:23

    Topics: Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Dipeptides; Endorphins; Enzyme Inhibitors; Guanylate Cyclase; Injections, Intraventricular; Injections, Spinal; Injections, Subcutaneous; Male; Methylene Blue; Mice; Morphine; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pain Measurement; Pyrazoles; Receptors, Opioid; Spinal Cord; Sulfoxides

2000
Side-effects of analgesic kyotorphin derivatives: advantages over clinical opioid drugs.
    Amino acids, 2013, Volume: 45, Issue:1

    Topics: Analgesics, Opioid; Animals; Blood Pressure; Constipation; Endorphins; Ibuprofen; Locomotion; Male; Morphine; Pain; Rats; Rats, Wistar; Tramadol

2013